LOCUS       DBGZHO010000001       160276 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.001, whole genome shotgun sequence.
ACCESSION   DBGZHO010000001 DBGZHO010000000
VERSION     DBGZHO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 160276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 160276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..160276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.001"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(265..2451)
                     /locus_tag="ACN3HL_000001"
     CDS             complement(265..2451)
                     /locus_tag="ACN3HL_000001"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HHC8004917.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2669..3352
                     /locus_tag="ACN3HL_000002"
     CDS             2669..3352
                     /locus_tag="ACN3HL_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HHC8004918.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3433..4152)
                     /locus_tag="ACN3HL_000003"
     CDS             complement(3433..4152)
                     /locus_tag="ACN3HL_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HHC8004919.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4464..4670)
                     /locus_tag="ACN3HL_000004"
     CDS             complement(4464..4670)
                     /locus_tag="ACN3HL_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8004920.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4915..5517
                     /locus_tag="ACN3HL_000005"
     CDS             4915..5517
                     /locus_tag="ACN3HL_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HHC8004921.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5658..6938
                     /locus_tag="ACN3HL_000006"
     CDS             5658..6938
                     /locus_tag="ACN3HL_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HHC8004922.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6951..7679
                     /locus_tag="ACN3HL_000007"
     CDS             6951..7679
                     /locus_tag="ACN3HL_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHC8004923.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7748..9271)
                     /locus_tag="ACN3HL_000008"
     CDS             complement(7748..9271)
                     /locus_tag="ACN3HL_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HHC8004924.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKI
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9523..10704
                     /locus_tag="ACN3HL_000009"
     CDS             9523..10704
                     /locus_tag="ACN3HL_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHC8004925.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10764..12392)
                     /gene="treC"
                     /locus_tag="ACN3HL_000010"
     CDS             complement(10764..12392)
                     /gene="treC"
                     /locus_tag="ACN3HL_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HHC8004926.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12843..15554)
                     /locus_tag="ACN3HL_000011"
     CDS             complement(12843..15554)
                     /locus_tag="ACN3HL_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HHC8004927.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15564..16265)
                     /locus_tag="ACN3HL_000012"
     CDS             complement(15564..16265)
                     /locus_tag="ACN3HL_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8004928.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16451..17050
                     /locus_tag="ACN3HL_000013"
     CDS             16451..17050
                     /locus_tag="ACN3HL_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HHC8004929.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            17131..18144
                     /locus_tag="ACN3HL_000014"
     CDS             17131..18144
                     /locus_tag="ACN3HL_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HHC8004930.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            18252..19169
                     /gene="rbsK"
                     /locus_tag="ACN3HL_000015"
     CDS             18252..19169
                     /gene="rbsK"
                     /locus_tag="ACN3HL_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HHC8004931.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            19197..19592
                     /gene="rbsD"
                     /locus_tag="ACN3HL_000016"
     CDS             19197..19592
                     /gene="rbsD"
                     /locus_tag="ACN3HL_000016"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HHC8004932.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19592..20965
                     /locus_tag="ACN3HL_000017"
     CDS             19592..20965
                     /locus_tag="ACN3HL_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8004933.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21322..23466
                     /locus_tag="ACN3HL_000018"
     CDS             21322..23466
                     /locus_tag="ACN3HL_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HHC8004934.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23518..24558)
                     /locus_tag="ACN3HL_000019"
     CDS             complement(23518..24558)
                     /locus_tag="ACN3HL_000019"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HHC8004935.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24835..26637)
                     /locus_tag="ACN3HL_000020"
     CDS             complement(24835..26637)
                     /locus_tag="ACN3HL_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8004936.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26651..27403)
                     /locus_tag="ACN3HL_000021"
     CDS             complement(26651..27403)
                     /locus_tag="ACN3HL_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8004937.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27412..27774)
                     /locus_tag="ACN3HL_000022"
     CDS             complement(27412..27774)
                     /locus_tag="ACN3HL_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HHC8004938.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27950..28822)
                     /locus_tag="ACN3HL_000023"
     CDS             complement(27950..28822)
                     /locus_tag="ACN3HL_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHC8004939.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28873..29361)
                     /locus_tag="ACN3HL_000024"
     CDS             complement(28873..29361)
                     /locus_tag="ACN3HL_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HHC8004940.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29499..30290)
                     /locus_tag="ACN3HL_000025"
     CDS             complement(29499..30290)
                     /locus_tag="ACN3HL_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HHC8004941.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30345..30953)
                     /locus_tag="ACN3HL_000026"
     CDS             complement(30345..30953)
                     /locus_tag="ACN3HL_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HHC8004942.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30946..31263)
                     /locus_tag="ACN3HL_000027"
     CDS             complement(30946..31263)
                     /locus_tag="ACN3HL_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHC8004943.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31419..32147)
                     /locus_tag="ACN3HL_000028"
     CDS             complement(31419..32147)
                     /locus_tag="ACN3HL_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HHC8004944.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32306..33187
                     /locus_tag="ACN3HL_000029"
     CDS             32306..33187
                     /locus_tag="ACN3HL_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8004945.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33424..34467)
                     /locus_tag="ACN3HL_000030"
     CDS             complement(33424..34467)
                     /locus_tag="ACN3HL_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8004946.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34470..35138)
                     /locus_tag="ACN3HL_000031"
     CDS             complement(34470..35138)
                     /locus_tag="ACN3HL_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8004947.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35280..37616
                     /locus_tag="ACN3HL_000032"
     CDS             35280..37616
                     /locus_tag="ACN3HL_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HHC8004948.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37732..38043)
                     /locus_tag="ACN3HL_000033"
     CDS             complement(37732..38043)
                     /locus_tag="ACN3HL_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8004949.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            38224..39699
                     /locus_tag="ACN3HL_000034"
     CDS             38224..39699
                     /locus_tag="ACN3HL_000034"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HHC8004950.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39746..40330
                     /locus_tag="ACN3HL_000035"
     CDS             39746..40330
                     /locus_tag="ACN3HL_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HHC8004951.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40332..40751
                     /locus_tag="ACN3HL_000036"
     CDS             40332..40751
                     /locus_tag="ACN3HL_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HHC8004952.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(41032..41316)
                     /locus_tag="ACN3HL_000037"
     CDS             complement(41032..41316)
                     /locus_tag="ACN3HL_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HHC8004953.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41548..42258)
                     /locus_tag="ACN3HL_000038"
     CDS             complement(41548..42258)
                     /locus_tag="ACN3HL_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HHC8004954.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42255..43727)
                     /locus_tag="ACN3HL_000039"
     CDS             complement(42255..43727)
                     /locus_tag="ACN3HL_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HHC8004955.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43865..44338
                     /locus_tag="ACN3HL_000040"
     CDS             43865..44338
                     /locus_tag="ACN3HL_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHC8004956.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44491..45042)
                     /locus_tag="ACN3HL_000041"
     CDS             complement(44491..45042)
                     /locus_tag="ACN3HL_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHC8004957.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45147..45677
                     /locus_tag="ACN3HL_000042"
     CDS             45147..45677
                     /locus_tag="ACN3HL_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HHC8004958.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46160..46603)
                     /locus_tag="ACN3HL_000043"
     CDS             complement(46160..46603)
                     /locus_tag="ACN3HL_000043"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8004959.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46619..47779)
                     /locus_tag="ACN3HL_000044"
     CDS             complement(46619..47779)
                     /locus_tag="ACN3HL_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HHC8004960.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48286..49986
                     /locus_tag="ACN3HL_000045"
     CDS             48286..49986
                     /locus_tag="ACN3HL_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8004961.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLHA
                     "
     gene            complement(50088..50921)
                     /locus_tag="ACN3HL_000046"
     CDS             complement(50088..50921)
                     /locus_tag="ACN3HL_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HHC8004962.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51225..53390)
                     /locus_tag="ACN3HL_000047"
     CDS             complement(51225..53390)
                     /locus_tag="ACN3HL_000047"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HHC8004963.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53650..55944
                     /locus_tag="ACN3HL_000048"
     CDS             53650..55944
                     /locus_tag="ACN3HL_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HHC8004964.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55937..56602
                     /gene="pgmB"
                     /locus_tag="ACN3HL_000049"
     CDS             55937..56602
                     /gene="pgmB"
                     /locus_tag="ACN3HL_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HHC8004965.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56595..57602
                     /locus_tag="ACN3HL_000050"
     CDS             56595..57602
                     /locus_tag="ACN3HL_000050"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HHC8004966.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57624..58643
                     /locus_tag="ACN3HL_000051"
     CDS             57624..58643
                     /locus_tag="ACN3HL_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8004967.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58924..60291)
                     /gene="nhaC"
                     /locus_tag="ACN3HL_000052"
     CDS             complement(58924..60291)
                     /gene="nhaC"
                     /locus_tag="ACN3HL_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HHC8004968.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(60400..61821)
                     /gene="tyrP"
                     /locus_tag="ACN3HL_000053"
     CDS             complement(60400..61821)
                     /gene="tyrP"
                     /locus_tag="ACN3HL_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HHC8004969.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(62064..63941)
                     /gene="tdc"
                     /locus_tag="ACN3HL_000054"
     CDS             complement(62064..63941)
                     /gene="tdc"
                     /locus_tag="ACN3HL_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HHC8004970.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64232..65488)
                     /gene="tyrS"
                     /locus_tag="ACN3HL_000055"
     CDS             complement(64232..65488)
                     /gene="tyrS"
                     /locus_tag="ACN3HL_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HHC8004971.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65600..65805)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            66068..67369
                     /locus_tag="ACN3HL_000056"
     CDS             66068..67369
                     /locus_tag="ACN3HL_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHC8004972.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67438..68037)
                     /locus_tag="ACN3HL_000057"
     CDS             complement(67438..68037)
                     /locus_tag="ACN3HL_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8004973.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68292..69173
                     /locus_tag="ACN3HL_000058"
     CDS             68292..69173
                     /locus_tag="ACN3HL_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHC8004974.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69186..70796
                     /locus_tag="ACN3HL_000059"
     CDS             69186..70796
                     /locus_tag="ACN3HL_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8004975.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAKGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70873..71532)
                     /locus_tag="ACN3HL_000060"
     CDS             complement(70873..71532)
                     /locus_tag="ACN3HL_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHC8004976.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71815..72480)
                     /locus_tag="ACN3HL_000061"
     CDS             complement(71815..72480)
                     /locus_tag="ACN3HL_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HHC8004977.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72627..73232)
                     /gene="dhaL"
                     /locus_tag="ACN3HL_000062"
     CDS             complement(72627..73232)
                     /gene="dhaL"
                     /locus_tag="ACN3HL_000062"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HHC8004978.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73260..74270)
                     /gene="dhaK"
                     /locus_tag="ACN3HL_000063"
     CDS             complement(73260..74270)
                     /gene="dhaK"
                     /locus_tag="ACN3HL_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HHC8004979.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74245..74640)
                     /gene="dhaM"
                     /locus_tag="ACN3HL_000064"
     CDS             complement(74245..74640)
                     /gene="dhaM"
                     /locus_tag="ACN3HL_000064"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HHC8004980.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74794..75114
                     /locus_tag="ACN3HL_000065"
     CDS             74794..75114
                     /locus_tag="ACN3HL_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HHC8004981.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75226..76083)
                     /locus_tag="ACN3HL_000066"
     CDS             complement(75226..76083)
                     /locus_tag="ACN3HL_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HHC8004982.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(76191..77495)
                     /locus_tag="ACN3HL_000067"
     CDS             complement(76191..77495)
                     /locus_tag="ACN3HL_000067"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHC8004983.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77492..78001)
                     /locus_tag="ACN3HL_000068"
     CDS             complement(77492..78001)
                     /locus_tag="ACN3HL_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8004984.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78176..80311)
                     /locus_tag="ACN3HL_000069"
     CDS             complement(78176..80311)
                     /locus_tag="ACN3HL_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HHC8004985.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80394..82049)
                     /locus_tag="ACN3HL_000070"
     CDS             complement(80394..82049)
                     /locus_tag="ACN3HL_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8004986.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(82051..82365)
                     /locus_tag="ACN3HL_000071"
     CDS             complement(82051..82365)
                     /locus_tag="ACN3HL_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHC8004987.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82535..82795
                     /locus_tag="ACN3HL_000072"
     CDS             82535..82795
                     /locus_tag="ACN3HL_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HHC8004988.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82809..83123
                     /locus_tag="ACN3HL_000073"
     CDS             82809..83123
                     /locus_tag="ACN3HL_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HHC8004989.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83853..84407)
                     /locus_tag="ACN3HL_000074"
     CDS             complement(83853..84407)
                     /locus_tag="ACN3HL_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HHC8004990.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84533..86462)
                     /locus_tag="ACN3HL_000075"
                     /pseudo
     CDS             complement(84533..86462)
                     /locus_tag="ACN3HL_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86768..87484)
                     /locus_tag="ACN3HL_000076"
     CDS             complement(86768..87484)
                     /locus_tag="ACN3HL_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HHC8004991.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87485..89308)
                     /gene="glpO"
                     /locus_tag="ACN3HL_000077"
     CDS             complement(87485..89308)
                     /gene="glpO"
                     /locus_tag="ACN3HL_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HHC8004992.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89322..90818)
                     /gene="glpK"
                     /locus_tag="ACN3HL_000078"
     CDS             complement(89322..90818)
                     /gene="glpK"
                     /locus_tag="ACN3HL_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HHC8004993.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90954..92414)
                     /locus_tag="ACN3HL_000079"
     CDS             complement(90954..92414)
                     /locus_tag="ACN3HL_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8004994.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92404..93699)
                     /locus_tag="ACN3HL_000080"
     CDS             complement(92404..93699)
                     /locus_tag="ACN3HL_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8004995.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(94031..94708)
                     /locus_tag="ACN3HL_000081"
     CDS             complement(94031..94708)
                     /locus_tag="ACN3HL_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HHC8004996.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94738..95829)
                     /locus_tag="ACN3HL_000082"
     CDS             complement(94738..95829)
                     /locus_tag="ACN3HL_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HHC8004997.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(95930..96364)
                     /locus_tag="ACN3HL_000083"
     CDS             complement(95930..96364)
                     /locus_tag="ACN3HL_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HHC8004998.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96948..98405)
                     /locus_tag="ACN3HL_000084"
     CDS             complement(96948..98405)
                     /locus_tag="ACN3HL_000084"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8004999.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98402..100297)
                     /locus_tag="ACN3HL_000085"
     CDS             complement(98402..100297)
                     /locus_tag="ACN3HL_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHC8005000.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100355..102130)
                     /locus_tag="ACN3HL_000086"
     CDS             complement(100355..102130)
                     /locus_tag="ACN3HL_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHC8005001.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102180..103676)
                     /locus_tag="ACN3HL_000087"
     CDS             complement(102180..103676)
                     /locus_tag="ACN3HL_000087"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8005002.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103870..105492)
                     /locus_tag="ACN3HL_000088"
     CDS             complement(103870..105492)
                     /locus_tag="ACN3HL_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HHC8005003.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105820..107133)
                     /locus_tag="ACN3HL_000089"
     CDS             complement(105820..107133)
                     /locus_tag="ACN3HL_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HHC8005004.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107378..107602)
                     /locus_tag="ACN3HL_000090"
     CDS             complement(107378..107602)
                     /locus_tag="ACN3HL_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005005.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107622..108044)
                     /locus_tag="ACN3HL_000091"
     CDS             complement(107622..108044)
                     /locus_tag="ACN3HL_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8005006.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(108186..108896)
                     /locus_tag="ACN3HL_000092"
     CDS             complement(108186..108896)
                     /locus_tag="ACN3HL_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HHC8005007.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108914..109411)
                     /locus_tag="ACN3HL_000093"
     CDS             complement(108914..109411)
                     /locus_tag="ACN3HL_000093"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005008.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109448..109900)
                     /locus_tag="ACN3HL_000094"
     CDS             complement(109448..109900)
                     /locus_tag="ACN3HL_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHC8005009.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(110035..110640)
                     /locus_tag="ACN3HL_000095"
     CDS             complement(110035..110640)
                     /locus_tag="ACN3HL_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHC8005010.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(111090..111710)
                     /locus_tag="ACN3HL_000096"
     CDS             complement(111090..111710)
                     /locus_tag="ACN3HL_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8005011.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111712..112581)
                     /locus_tag="ACN3HL_000097"
     CDS             complement(111712..112581)
                     /locus_tag="ACN3HL_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HHC8005012.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112604..113011)
                     /locus_tag="ACN3HL_000098"
     CDS             complement(112604..113011)
                     /locus_tag="ACN3HL_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHC8005013.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(113030..114319)
                     /locus_tag="ACN3HL_000099"
     CDS             complement(113030..114319)
                     /locus_tag="ACN3HL_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHC8005014.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(114346..114648)
                     /locus_tag="ACN3HL_000100"
     CDS             complement(114346..114648)
                     /locus_tag="ACN3HL_000100"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8005015.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(114673..116766)
                     /locus_tag="ACN3HL_000101"
     CDS             complement(114673..116766)
                     /locus_tag="ACN3HL_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HHC8005016.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(117255..118019)
                     /locus_tag="ACN3HL_000102"
     CDS             complement(117255..118019)
                     /locus_tag="ACN3HL_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HHC8005017.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(118130..118999)
                     /gene="mdcB"
                     /locus_tag="ACN3HL_000103"
     CDS             complement(118130..118999)
                     /gene="mdcB"
                     /locus_tag="ACN3HL_000103"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HHC8005018.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(119024..120100)
                     /locus_tag="ACN3HL_000104"
     CDS             complement(119024..120100)
                     /locus_tag="ACN3HL_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HHC8005019.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(120124..120717)
                     /locus_tag="ACN3HL_000105"
     CDS             complement(120124..120717)
                     /locus_tag="ACN3HL_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HHC8005020.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(120721..122397)
                     /gene="mdcD"
                     /locus_tag="ACN3HL_000106"
     CDS             complement(120721..122397)
                     /gene="mdcD"
                     /locus_tag="ACN3HL_000106"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HHC8005021.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(122387..122686)
                     /locus_tag="ACN3HL_000107"
     CDS             complement(122387..122686)
                     /locus_tag="ACN3HL_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HHC8005022.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(122788..124434)
                     /gene="mdcA"
                     /locus_tag="ACN3HL_000108"
     CDS             complement(122788..124434)
                     /gene="mdcA"
                     /locus_tag="ACN3HL_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HHC8005023.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(124441..125352)
                     /locus_tag="ACN3HL_000109"
     CDS             complement(124441..125352)
                     /locus_tag="ACN3HL_000109"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HHC8005024.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            125472..126329
                     /locus_tag="ACN3HL_000110"
     CDS             125472..126329
                     /locus_tag="ACN3HL_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8005025.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(126516..126878)
                     /locus_tag="ACN3HL_000111"
     CDS             complement(126516..126878)
                     /locus_tag="ACN3HL_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HHC8005026.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(127067..127249)
                     /locus_tag="ACN3HL_000112"
     CDS             complement(127067..127249)
                     /locus_tag="ACN3HL_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005027.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            127224..128663
                     /locus_tag="ACN3HL_000113"
     CDS             127224..128663
                     /locus_tag="ACN3HL_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005028.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(128670..131222)
                     /locus_tag="ACN3HL_000114"
     CDS             complement(128670..131222)
                     /locus_tag="ACN3HL_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HHC8005029.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(131336..132667)
                     /locus_tag="ACN3HL_000115"
     CDS             complement(131336..132667)
                     /locus_tag="ACN3HL_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8005030.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(132633..134111)
                     /locus_tag="ACN3HL_000116"
     CDS             complement(132633..134111)
                     /locus_tag="ACN3HL_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8005031.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(134416..136251)
                     /gene="tdc"
                     /locus_tag="ACN3HL_000117"
     CDS             complement(134416..136251)
                     /gene="tdc"
                     /locus_tag="ACN3HL_000117"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HHC8005032.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            136721..138148
                     /locus_tag="ACN3HL_000118"
     CDS             136721..138148
                     /locus_tag="ACN3HL_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005033.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(138240..138605)
                     /locus_tag="ACN3HL_000119"
     CDS             complement(138240..138605)
                     /locus_tag="ACN3HL_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HHC8005034.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(138602..138967)
                     /locus_tag="ACN3HL_000120"
     CDS             complement(138602..138967)
                     /locus_tag="ACN3HL_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HHC8005035.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(139159..139407)
                     /locus_tag="ACN3HL_000121"
     CDS             complement(139159..139407)
                     /locus_tag="ACN3HL_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005036.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            139406..139534
                     /locus_tag="ACN3HL_000122"
     CDS             139406..139534
                     /locus_tag="ACN3HL_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HHC8005037.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            139591..141285
                     /locus_tag="ACN3HL_000123"
     CDS             139591..141285
                     /locus_tag="ACN3HL_000123"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HHC8005038.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            141352..141681
                     /locus_tag="ACN3HL_000124"
     CDS             141352..141681
                     /locus_tag="ACN3HL_000124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005039.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFL
                     TWLDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLP
                     RGYEKGV"
     gene            142059..143192
                     /locus_tag="ACN3HL_000125"
     CDS             142059..143192
                     /locus_tag="ACN3HL_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HHC8005040.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            143223..143543
                     /locus_tag="ACN3HL_000126"
     CDS             143223..143543
                     /locus_tag="ACN3HL_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HHC8005041.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(143572..144036)
                     /locus_tag="ACN3HL_000127"
     CDS             complement(143572..144036)
                     /locus_tag="ACN3HL_000127"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005042.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(144167..145420)
                     /locus_tag="ACN3HL_000128"
     CDS             complement(144167..145420)
                     /locus_tag="ACN3HL_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHC8005043.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLASGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(145449..145766)
                     /locus_tag="ACN3HL_000129"
     CDS             complement(145449..145766)
                     /locus_tag="ACN3HL_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHC8005044.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(145792..146112)
                     /locus_tag="ACN3HL_000130"
     CDS             complement(145792..146112)
                     /locus_tag="ACN3HL_000130"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8005045.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(146576..147991)
                     /locus_tag="ACN3HL_000131"
     CDS             complement(146576..147991)
                     /locus_tag="ACN3HL_000131"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8005046.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(148008..149324)
                     /locus_tag="ACN3HL_000132"
     CDS             complement(148008..149324)
                     /locus_tag="ACN3HL_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8005047.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(149474..150172)
                     /locus_tag="ACN3HL_000133"
     CDS             complement(149474..150172)
                     /locus_tag="ACN3HL_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HHC8005048.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(150461..151454)
                     /locus_tag="ACN3HL_000134"
                     /pseudo
     CDS             complement(150461..151454)
                     /locus_tag="ACN3HL_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(151535..152368)
                     /gene="msrA"
                     /locus_tag="ACN3HL_000135"
     CDS             complement(151535..152368)
                     /gene="msrA"
                     /locus_tag="ACN3HL_000135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HHC8005049.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(152602..153345)
                     /gene="truA"
                     /locus_tag="ACN3HL_000136"
     CDS             complement(152602..153345)
                     /gene="truA"
                     /locus_tag="ACN3HL_000136"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HHC8005050.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(153536..154171)
                     /locus_tag="ACN3HL_000137"
     CDS             complement(153536..154171)
                     /locus_tag="ACN3HL_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HHC8005051.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(154318..155538)
                     /gene="sstT"
                     /locus_tag="ACN3HL_000138"
     CDS             complement(154318..155538)
                     /gene="sstT"
                     /locus_tag="ACN3HL_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HHC8005052.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            complement(155880..156557)
                     /locus_tag="ACN3HL_000139"
     CDS             complement(155880..156557)
                     /locus_tag="ACN3HL_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HHC8005053.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(156808..157350)
                     /locus_tag="ACN3HL_000140"
     CDS             complement(156808..157350)
                     /locus_tag="ACN3HL_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HHC8005054.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(157355..157582)
                     /locus_tag="ACN3HL_000141"
     CDS             complement(157355..157582)
                     /locus_tag="ACN3HL_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HHC8005055.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(157661..159541)
                     /locus_tag="ACN3HL_000142"
     CDS             complement(157661..159541)
                     /locus_tag="ACN3HL_000142"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHC8005056.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            159842..160162
                     /locus_tag="ACN3HL_000143"
     CDS             159842..160162
                     /locus_tag="ACN3HL_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHC8005057.1"
                     /translation="MDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLKLLIHT
                     ACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECFFIYDI
                     IASK"
BASE COUNT        47301 a        33237 c        27802 g        51936 t
ORIGIN      
        1 aaaatcaaaa taactgatta tttacgtttg aataatgaga atttttctat atattctcta
       61 ttttgataat agtattctca ttttcaaaat aaataaggga ggtgtgacaa aattcttgtc
      121 acacctccct tttccgaata aactgtgttc cagaaatagc ttcttcgaaa ataagctgaa
      181 atttcacaaa aatttgagaa gcaattttcg tacattcctt cttctttctt gaaactgacc
      241 acttctgtca caccctctct tctatcactt tccttttttc acacgactcc cggtttcttt
      301 gataaatctc gatactttca attttcttga atttttcatt tgaggtacac atagatacag
      361 acgatttctt gctctagtca tcgcaacata aaatagtctt cgttcttctt ctatcgtcgt
      421 tactggttct gcttttattt cattaaagtc gattactttc ttttctgtcg ctccgttata
      481 aggcaaactt ccttcgttac aaccaatcaa aaagacattt cggtaactaa gacctttact
      541 tttgtgaatg ctctggatac atagtgcatc aagttttcct tgtctgtaag caatcaagcg
      601 ggtttttaat tctttagctg tcgcttgggt ttcttgcgat aaggcttgga gtcttctgaa
      661 agtagcatgc tgctttactt cttctcgtat ccattcttga tcactctggt cgatttcctt
      721 agctatacgt ggcagatgaa gatagctttg aacaagcgaa tagatttctt gatgctggtc
      781 tgttttacgc aacgcttcct caaactctcg gatttctgca gatttcgatt ttaaattggg
      841 gcttatcgac aaaatataat ctgcaacggc tatattttga tatttaggag aaaagtattg
      901 atcgcattca ctttttttca ggtagcagtc tgccatcagc tgccggagca attgctggta
      961 ggcctgattt ttcttttgca gattcagtgc tgtttgccaa tgaacaattt tttgatagaa
     1021 atgttggaaa gacttgatac caaagatacc ttcatatgga ctatctgctt ccagtacaaa
     1081 aggaatattc gttttcagca gagattggac aagctgctgc gtttgtgaag ctgatcggta
     1141 taatatgatt gattccttat atttcccatt tttttgaata aatgtctgaa tttgtttgat
     1201 tagccactga ctttctgctt tagtatcaga aaacaaatag gcttccataa cacctgcttc
     1261 tttttgtgct ggaatcatcg cctttggtat ccgatcattt ttattatagc tgatcaatct
     1321 atttgctcct tggacaatag ctgcccgaga acgataatta gttaataaga aaagagtttt
     1381 ggtaggatat tctttttcaa agttcttgat gtatgctggc tctgatcctc tgaatccata
     1441 gatactctga tcatcatctc caacaacaat caacttgatc ctgttttcct ttgtcatccg
     1501 tttcacgatt tcccattgaa gtggattagt atcttgaaat tcatcaatga atagataatc
     1561 atatttttgg ccgatataat gctggatctc ctcattctcc aaagcgcttt tcagattttg
     1621 gagtacatca ttgaactcta gcaattgctg gcttcttttt tgttcttgga gttccgtgag
     1681 caatccatac agtcgttctg atatcggctg tcgtgcattc ttatcaatgg aatcatattt
     1741 ttctttaact aactgaacca tttcttctac tgaaaggttc atattctgcc aatagtctaa
     1801 ccgagaagca atcgtttttt ctccatattg atcaaatata taaagattat atttacgtat
     1861 cagctgttgc aaaacagcat tcactttttg tgcagtatcc tttgaaaagt ctccttgtat
     1921 tccttgcatt gctacttcag gaaattttcg acaaatttca ttgtatatcc taaaaaagat
     1981 actatggaat gttccgatat ggacagcggt ttttctctgg ctgaaattat ctactcgttt
     2041 ttttagttca tttgcagcgt tccttgtaaa agtgatcatt agtatgcgtt cttcgtctac
     2101 ttgtttttgc gtcatcagat aaacagcttt tgcacagatt gtttgcgttt tgccgctccc
     2161 agctcctgct atgattcgaa gatgtttctt catatcatat gtgatagctg ctttttgttc
     2221 ttgattgaag cgattatagg aacgtttctc catcatttta aagaaagagc tgtttccttc
     2281 actttctttt acttgtactt cttcctcaat aagtccgggt gcttcgccat aagccgcttc
     2341 ataggtagca atgatttctt cttgtagccg aaagacttgt tgaagctttt tatacttgtt
     2401 ctcccagcgt ttcaattctt tttgtaatcg gagaatttct ttttcattca actgattgat
     2461 ttccttccca tctttcttct ttgaatttgt ttatttcaag ttggttattt aaagtttcgt
     2521 tgtctatttt ttctttatac taacagacct ttctaaaaat gaaaatggga agcgatatga
     2581 ttttagtttt ctgaaaattt ttcctttttt tcaatcgttt atgctaagat aaggaagaca
     2641 aaaatattca taaaaggtga tgaaaaaaat gcagacttcc tttcacgagg ggcgtacaat
     2701 aggacttttg ctgacattta tcggaggagc catggacagt tatacttata tccaatatgg
     2761 tgcttttgcc tctgctcaaa ctggcaatat cattctatcg atcatccaag catttgacgg
     2821 agaatggcta agtgttggta aaaaagtatt gtctaccctt ttctttttct tagggattct
     2881 tctaacaaag tatctaattg attattttag aaaaaaagaa aaacatttct ggcgcttgtt
     2941 tgttctatat tatgaagcag tgattttttt ctttgttagt ttgacacccg tccatgagca
     3001 tcccgcatta gtaacgattt tgattgcttt tactgcatcg atccagtggg tagcttttga
     3061 taaaatcaac gggcgtgcct acactaattt atttacaact ggaaatttaa aaggggtagc
     3121 aacgaactta tatgattatt gtatttctaa agaaaaagca gattttgatc gatttttcca
     3181 ctatctaagt gtcgttcttg cctttatcgc aggagctatt gtccttgttt tctgtcatca
     3241 tctgtttggc gcccattcga ttttgatcgt ttccatttta tttttgatca tggccctcac
     3301 tcagacattt catttatggc aattttatca tacgaatcgg ttcactattt gatctcaatg
     3361 aatcaaaaaa actaagcaag atgctgctca cagagaaata tctgcgagtg agcaatttgc
     3421 ttagttttta tattatttag ttgtaaagat tccctttgct ttcgggttat ttgtagtgta
     3481 gcggatcgac tgggcatctg cctcttctgt cattttcttt gcccgcatct tgatttcttg
     3541 tacgatttgt tctccacatg ccggatcggc tacgaaatca tatttgtccc catcgatcac
     3601 tattttggga catatatcaa actgttcata ccactcttcg tatcgtcgat tgagttcttt
     3661 atagtaggaa tagagttcag gatcttgttc tagctgttca tattcccggc ctcttttttt
     3721 gattctcgct aacatagttt caaaggatac acgaatataa accagtagat ctggtttctt
     3781 ttgtggcgaa atttcttcta actccttcag catcgtttct aaaagacctt catactgctt
     3841 tacttctact tcagaaacac gccctaaatc tgcattcaaa tgaaacagca tactatcttc
     3901 gtagatggag cggtctagta cgttgtcatc atggctgaaa gcatctttga ttgccaaaaa
     3961 gcgtttgttc aaaaagaaaa tctgtaataa aaaagtatac ttttctggat tagaataaaa
     4021 tagcggcaat acttcattat cttccacgtt ctcataaaaa ggttttgttt ctaaatcttg
     4081 ggcaagcatt tcagttagtg tgcttttccc tgcaccgatc gttcctgcaa caatgatcac
     4141 aattatcggc atccttcctg taataaaatc tgttcttcat tttactactt catttataga
     4201 aataaaagcc ttgactttat ctgctcctta aaagctactt ctctaaaagt agccaaaagt
     4261 aactcctatt catgaaaata aaggctgtga caaaagtctt gtcgcagccc ttttttcaaa
     4321 taaacagtat tctcctgcca acacctcggt cacaaggcaa tattcataaa acatgaaaag
     4381 ctgtttttta acattattcc ttgtaactca gagctaaacg ggagactcac aacctcttta
     4441 tgctctcaac attttatctg tttttattct tctattgtac ttgatttgcg tacaactaac
     4501 tgccagtgca gattatgagc ggtatcattg tcttctactg cgcatttcat gacacgtatc
     4561 atcacactat tttcatagat tttttctatt tttcctttta ttggtgattc aaataaatca
     4621 gatttaaatg catatgtttc gccgacttca aacaattgtt cattttccat aagaatccct
     4681 ccatcacctt ttataaggtc agtaattttt taacataaat cactcgaaaa agcacaaact
     4741 tgtcataaaa agtacttttc gtatcaaaac tgtcactttt tttggtaagg ttcttggaaa
     4801 acgaagattt ttttaggaga tcatgacggt tttgatgtca aaaccacttt ttatgaaaca
     4861 aaagacgttt tttatttttt ttagcataaa atttgtggtg gaggtacgta tgagatgaaa
     4921 gataaagttg tgaacaaatt attagaagcc ttattcagcg gagacaaatc ggaagaagat
     4981 atggtgtatg tccaagtaaa atttgtctta gaagttttat tgaataatct tggaaaacta
     5041 gcggtcgttc tagtcttttc tctggtgaca ggctcatggg cggaaacagg aatcaccttt
     5101 ctttcttata tctgcatccg cagatatgct tatggattgc attccgactc tgaattcgtt
     5161 tgtctgctgt ggacactact ttatttatgg ggcgttccct tggtgatgaa acatctgcaa
     5221 ttgactatct ccttcccaat gatggtcttt ttgttaatca gctgcttttt gttactgctt
     5281 cgctatggat caagaggtac agcaatcaat cccattgaac ccgagaaacg tcccccatta
     5341 ttaaagaagg cgatcagcat gtttctaatt ttttctctca ttacgttatt tttctcagct
     5401 tcttactttt ctacctattt gctacttggg attgttttag aaatagctac gttgcttcct
     5461 attacaaact acttgatgaa ttttggagga atctttcatg aaaaaaacaa tcattaaaca
     5521 attaactaac ttatctgact tttttgtatc tggctgctgc tttggtatga gttctgaatt
     5581 caaaatccct gaaaaattaa aaaaataata cgccaattgt gctataattt ggtaaaaatc
     5641 aatgggagct gtactttatg tttttatggt ccatagcgtt gcaatatttg atttacacaa
     5701 tttgtatctt attgattgac catcacatcc gatacaaata tctgtttgcg ggagtcattc
     5761 tgatttcttg tattttgatt ggatgggtct attcgatttt agggattttt actgctctaa
     5821 ttgctatagg aatgctgatg cttacttttt tcttcttttc gacttcgcgt caacaattgg
     5881 tttacgcgct tccttttggg ttattgacgt cgcttttagg agatcactta acaagcatcg
     5941 gcgatttttt tgttttgaaa tcttcggtta ttgaaccagg agattcattg cagtattttc
     6001 acattgtctt atccgctttt ttatctgctt tattagcttt ttgtttaaaa aaatcgttag
     6061 agacttggtt tcacactgtg gaccgccgta tgatcggtac gatcgggaca ttgatattat
     6121 ttacatacta tatcattatt ttttataccc gtttttctgg tgaaacacct gatgtcttag
     6181 ctttgaatac gagttttttc attctatatc tgtgtgttgg cctgatcatc ttggtttatt
     6241 attggaaaat ctctaataag aaattagctg atcagttatt agagcaacaa gtcaggatgc
     6301 aacaggatta tatcaaagat ctagaaaaaa actatcaaga cttgagagaa ttcaaacatg
     6361 attaccaaaa tctgcttttt tctcttcaca gctatatttc agaaggcgac ttagaaggat
     6421 tacggtctta ttatgatcaa acgatattac ctacacgcca gatgatgaac ctttttccgg
     6481 ccaatctaag tatgttggat aatatgaaag ttcctgagat ccgtagttta ctgtcattaa
     6541 aactcatgat ggcacaggaa aaagggttga tcgtccagct tcattttcct gagccaatcg
     6601 aactggatac gaaacatacg gtaaaccttg tacgtatgct tggtattatc ttggacaatg
     6661 cgattgaagg agctagtgct gcaaagaaga aaaaaatcga attgaccata ctcaagaaga
     6721 atcattccgt gatgattcgt gtgatcaata caacaacaaa tacattaccg ttaaaccagt
     6781 tgaaacaaaa agggttctca acaaaaacaa atccaaaaaa cgaaggcctt ggcttgttta
     6841 tcttggatga attgacaaag accaatcctt atcttttcct tgaaacatca attgaaaacc
     6901 agcgtttttc tcaaacgatt tatatacaaa taaaataaag gagtaatgat atgattccca
     6961 tttatatttg tgaagacgat ccaaaacaat tagaagtttt atcaacggtg atcaaaaata
     7021 gaatcatgat tgaaaactta gacagttatg tccatatttc tacctctgat ccggaagaac
     7081 ttctcaatgc agccaagatc agaacttctt cttttggtat ttacttttta gatatcgaac
     7141 tagaagacag tgaaatggat ggtgtagcga tcggtaaatt gatccgtgaa ttagatcctt
     7201 taggaaaaat aatctatgtg acttcccata cggaaatgtc gatgaaaatc ttaaaaagca
     7261 acatcgaacc gactgattat atcgtcaaag aagatcttta tgatttaaaa gaaaatgtcg
     7321 agcatatcct gagcaaaatt ttcgaagatt ttcaaatgtc ccaaatccaa aaagatatct
     7381 tcaaaataga gtttaatgat gagatcaaat ttttaccgat caaagacatc caatattttt
     7441 ctacttcgct aggagcgcca cataaactgg aagtccattt gactcatgcc caattacaat
     7501 tctatgagaa gatcaaagaa atcgagaaaa tgcatcggaa ttttatccgt tgtcataaat
     7561 cctatgttat caatacacaa aatgtgcggt cgattaataa aaaaaccaga gaagtcacgt
     7621 tggcaaacgg cgagaccatc ccagcctcta tccgtggatt aaagaaattg atttcataaa
     7681 aagaaccgaa tagtttggac cgactaaatg accagccgat ccaaaccctt cggttctttt
     7741 ttgcctatca gtgcaaaagc atttcctgtg caatttcacg tccatccatt gtatctggat
     7801 aaaatgttgg ccaattctcc atttctttca gcaatacttc ttgactttca tttcctgcat
     7861 ataaatgaaa atgttcggag tcagccggtg caatcgtgtg atcactgaat tgaatatatc
     7921 taaaagcgcc actttcctta tcttctgctt cgaatagata ccttacgcca cggtttcctg
     7981 cctcgtaggt caagatttct ttccctacat aacgataatt tgaacgtttc gttgttccat
     8041 tcttaaacgt aaatgccatc tctttctcac tgatcttgat tgaagcaata tctgtttgat
     8101 agcccttcgt ataatattct ttatattctt gtgctgtctt atcctgattc aatttttctt
     8161 tatattcaaa aacaggatca aaagtcccat cttctacata cgtatctact gtttgccaag
     8221 ttcctgccca atctgaaaga gagcgatctt gtacatcctc gtcttcaaaa taaccgttgt
     8281 agacgctctt ttcttttttg ggggtcaaag tatcttctag cgggttttct gtctctgtcg
     8341 tttttttcaa cgcttcgagg tttgcttcca tgatagaaag atagttttct ccattttcta
     8401 tttgttcatt cgtcaatcct tccaaaggat tcaatacttc taaagataca cctgcttcgt
     8461 ttgctaacgt tctggcaata ctatctttgg cgttttcttc aaaataaata tagttgattc
     8521 catgttcttt aacaaagtgt ttcagttcag caattctcgc cgcagacggt tcttcactag
     8581 aagaaagacc agcaatcgat acttgattca atccatattc taacgctaga tagttgaatg
     8641 cagcatgttg cgtgacaaaa gatctttgtt ttgcttgctt aaaggtttct tgataaagct
     8701 gatggagtgc ttgaagtttc tcggtatagg ctgctgcatt ttttgtccat acttcctgtt
     8761 tttctgggta agcttcaatc agctgatcac gtatgtttgc tacctgcttg attgctaaac
     8821 ttggagctag ccatacatgt gggtctagct catgtgtatg gccttcttcc ccgtgttcat
     8881 ggtcatgatc atgtccttct tcacttcccg gaagtaaaag cataccttct gtcgctttta
     8941 tcgtatggac attgccttct tgtaatattt tttggattgc ggggacccat gtttccatgt
     9001 tttcatcatt ataaacaaag atatctgtat cttggatctt tgccatgtct ttagcagaag
     9061 gttcataatc gtgggaatca gtccctgctg gaatcaataa ctctacttct ccttcatccc
     9121 cgacgattgc ttttgtaaaa tcatacatgg gataaaaggt cgtcatcacg ctcaattttt
     9181 ctttactgtc ctcggctttc ccacttgccc cgcaagcagt taacatacct gctaaaacca
     9241 gcatggccaa tatacctatc aatcgtttca tttatgacac tcctcttctc atcttctttc
     9301 atttgaatgt tccgattcgc ttttcgcaaa ccgtaatagt tacgttttag caacaggatt
     9361 taatttatca tatggttaaa agaactgtca agcgttttct tattttaatt gatgagaaag
     9421 tttatatgaa tgattgacga tatttttgca atcaacctct atcattttcc ttttataccc
     9481 gcttttgtct ataatgaagt tatagataaa ggaggaaaaa gagtgaaaaa agaaacagat
     9541 acaacgaatc gtttgatccg ctttttagga ggaaaaacct cttactatgt tttaggaata
     9601 gttatcttac ttgcgctgat catttatttt ttccatcaga tctcgtttat attcaagcct
     9661 gtcggaatca ttatcgctac tatcttgccc ccattattgt ttgcactgat cttgtattat
     9721 cttttggaac cagtcatcaa acgtttgagc aagcaccttt cgaggaactt gtcagtcatt
     9781 atcgtttatg tgattatttt atttttattg gggcttggaa gcatatggct tattcctttt
     9841 cttgaagaac aggcaaagac attgatcagt agtttgccag atttgtttca agattttcaa
     9901 gagagtctcc gacaattttt ggagaaaaca ccttttgccg attcatttaa tcaatttttc
     9961 gcttctattg acgacgtgac gtctgatata gctggattta ttggaaatta ttgggaaagt
    10021 ggcgcacaac ggatcagcaa cattttttca actgttacag ctatttttat tactttattt
    10081 actggtccaa ttgtcgcttt tttccttttg agagatcctc aaaaatttta tcagtcagtt
    10141 ttagcgattg tcccaccagc atttcgtaca gattttaaaa atttgacaaa gattgctaat
    10201 caacaattgg gttcatttct aaaggggcaa atcattgctt catttatcct tggagcagtc
    10261 tactgggttt gtttcttact gatcggatta gaatttgcta gtgttttagc tatttctgct
    10321 gggttgttat gtatcattcc atatattggg ccgtttatcg ccttctttcc aggtttgatc
    10381 attgcattcc aagactctac ttttatggct gtcaaatttg tcattgtctg gtttgccgta
    10441 caacttctcc acggtgactt ggtgattcct cgagtaatgg gtgatcgttt acagatccat
    10501 ccgattacga tcttaatcgt tttacttgtc atgggtgatc taatgggaat tgtgggcgtt
    10561 atttttggta ttcctatcta tacgttagtc aaattactcg ttacttttat tttccgtaaa
    10621 ttcaaacaac gctacaataa attttatggc gataaaggag agtatgaaaa ctcttcattt
    10681 tctgaagaag attattttaa ataaaacaca aaacgtcgat cttacgagaa tagctcgtag
    10741 gaacgacgtt ttgtgttttt gttttaattt ttcagcaaag caattgcctg gtatggtttt
    10801 agctccagac tttgatgaag aacagtatcg gaataattat cgataagaat attggcttct
    10861 gtgaatcctt ctgggatggc gatccttgta tctttatcat agaaatttgt taatacaagc
    10921 agctgctgtc cttcaaattg gcgaagaaag ccataaactt ccggatgatt tgcttcataa
    10981 gcatgataat ctccttgtgc aacgattgga tatgtttttc tcagccgaat caatttcttg
    11041 taataggaca aaatagaatc ttcagaagat agttcttttt ctacattaat ctcttctagc
    11101 ttgcctccaa cttttaacca aggtttccct gtagtaaatc ctgcttgttc tgtgtctgac
    11161 cattgcatgg gtgttcgaga gttatcgcga gattttgctt tgatccgacg aaacgcttct
    11221 ttttctgtga atccttgttc aaggagtaac ttataagcat tcaaactttc tacgtcaata
    11281 tagtcggaaa tcgatgaata gtctgggtcg atcatgccga tttcttctcc catataaata
    11341 tagggcgtcc cacggttcaa atggatcatg gttgctagca tctctgctcc ttgttttcga
    11401 tactgatcga tagctacaaa tcgattgagc gcacgtggct gatcatgatt attaaaaaat
    11461 agagcattcc agccgttacc ctcactcatc ttttctcccc atgtatgaaa tagtcgcttt
    11521 aattctgcaa aatcaaatgg aggagtagac catttattcc cattttcata atcgactttc
    11581 aaatgatgga aattaaagac cattgataat tcttctctac taggttctgt atacaagata
    11641 caattttcga tcgtcgtaga gctcatttca ccgactgtga tgatagtgga atccgtccca
    11701 aacgttgctt ggttcaattc ttttagatac gtatgggtga ttggtttgtc cgtatattca
    11761 ggtttgccat cattttcttt attatttttc aattgttcgt ctttaccgat aacattgata
    11821 acatcgaaac ggaatccttt tacccctttt tccatccaaa aacgaacaac tttgaatagt
    11881 tcctctctta ctgcttggtt ccgccagttc aagtcagctt gtgtccgatc atataagtgc
    11941 aaataatatt tccccgtatc tccaaatggc gaccaagcac ttccaccaaa ttttgatacc
    12001 caatccgttg gctcttctct taaaatgaag aagtcctgat aatgctggtc ccctgctagt
    12061 gcttttttga accattcatg ttctgtcgaa acgtgattca gcaccatatc gagcatgatt
    12121 tctatccggt atttctttgc ttcggctatt agctgttcga attcctccat cgtaccaaag
    12181 ataggatcga tggctgtgta atcagagata tcataaccgt tgtctttttg agggcttgga
    12241 taaatagggt ttagccaaat catgtcgatg cctagatcat tcagatacgg gagtttttct
    12301 ttgattcctt ttaaatctcc aattccatca ccattactgt ctttgtaaga tttgggatag
    12361 atttggtaaa tgactttgtc tttaaatgtc atggatattt acctccattc aactgattta
    12421 ttacctacca caacttatat atacaagtta tcatttatta ttataactga accgaaagcg
    12481 tttgtaaaat ttatctttat acattctaag aggtctgttg cccaataaaa aacaagagat
    12541 cagacatgta tttgtctatc ctcttgttta aaatagcaaa atattcttgt ttcttctata
    12601 aatggtgttc aaaagctttt atctacggca atcagtcttc tcaaatgtaa aacatgagga
    12661 gctaatttta tttgagtatt ctttttgctc gatgcaggac ggctttttta caacctctga
    12721 ttcatggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa aatatgaaaa
    12781 actattttgc cgtttgtttc tctaatactc aggtcaaacc gctgatttca caacctctgt
    12841 ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt gaaatgggta
    12901 acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac ataagcccac
    12961 catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa gatgaagtca
    13021 gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa gatgatattt
    13081 tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt tattgtagat
    13141 aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac gataaaagcc
    13201 agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc cattgattct
    13261 tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc tgtggcaagc
    13321 agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg cagcaaaaat
    13381 gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga catataaata
    13441 aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc tttttgatct
    13501 tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc tactttttgc
    13561 gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc agttaaatgg
    13621 ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact ttgcgaagca
    13681 tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc atttactttt
    13741 tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga tgaatccaat
    13801 gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac agaacttaga
    13861 gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat tccgataatc
    13921 gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt ttgattaaag
    13981 ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc tggcttcggt
    14041 gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa aacgatcatt
    14101 gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg cggccagtca
    14161 taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa aatgatcctt
    14221 ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga ggctagactt
    14281 gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc ctttaatgtc
    14341 ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt gatcaatgcg
    14401 gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg atcagacaga
    14461 tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta tgatggttta
    14521 gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga ggccagttca
    14581 cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg ttgagataat
    14641 gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc tgactgttgc
    14701 gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg tgctttgcca
    14761 tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt cagctcttct
    14821 aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt ttgctccatt
    14881 ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa atcaagatat
    14941 aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa ataatcgacg
    15001 ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa tggagaacgg
    15061 acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat ctgataaata
    15121 tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg gtttggtttt
    15181 tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt gttataagaa
    15241 aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt tcctgtttct
    15301 acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa gccaccagta
    15361 gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat cgttttttgc
    15421 atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat gacaataagg
    15481 atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc tttaagatat
    15541 gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga aggatgatca
    15601 tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc agcgatgggc
    15661 gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct gctagcgttt
    15721 tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt cggttcatca
    15781 cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct ctgctgttcg
    15841 cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac ttgcctcaat
    15901 acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac attttctttt
    15961 gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc tgttcgtcgg
    16021 taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat aatgatctga
    16081 ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt tcctgctcca
    16141 cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat atcgtcattt
    16201 gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac ttcgacatac
    16261 ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat cgaatgcgtt
    16321 ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg aatcctttaa
    16381 tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt tatttgaaag
    16441 aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa aaactgcttt
    16501 tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc cacacactgc
    16561 agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta ccgctgcctt
    16621 gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac aaactgatat
    16681 gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga aggattcttt
    16741 gaaagataca gataatatgt tgactatcac aaaatacaat ccaagtgctt tttttggtac
    16801 ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa gcggtgtagc
    16861 gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt accatatcgt
    16921 gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt tcataaaaaa
    16981 gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag ctatccaaca
    17041 aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt catgggaaaa
    17101 taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac aatcaaagaa
    17161 gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa tggaaatacg
    17221 gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga attaggctat
    17281 cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat tggtgtactc
    17341 gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga ggatatcttg
    17401 tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca aaaagaaatc
    17461 gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc gacttctgct
    17521 gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt cattgttttg
    17581 gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt tcgcggtggt
    17641 tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct tgtctatcct
    17701 gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc tcttgatgtt
    17761 taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa acaaggtggc
    17821 taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc tttaaatgat
    17881 gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat ccctgaagac
    17941 tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc gaaactgaca
    18001 acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt gttagatcgg
    18061 atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt agaaaaaaga
    18121 ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc gaactattaa
    18181 aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg agatagttgg
    18241 aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac actacccttc
    18301 gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt tttcacgctg
    18361 gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca cggacatctt
    18421 ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta ctgacaaaag
    18481 aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga caagcaatga
    18541 ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca aataatgctt
    18601 tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac tttattattg
    18661 ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca aaagacgcag
    18721 gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact gaactacttg
    18781 aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca ggaatcagag
    18841 tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta ggtattggaa
    18901 cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa gaacacggta
    18961 tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat acatttattg
    19021 gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg atcctttatg
    19081 gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct atcccttacc
    19141 gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa acaaacatga
    19201 aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg gggcactttg
    19261 ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa aaaatagatt
    19321 tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt ttagaagaac
    19381 ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg gaaatattgg
    19441 aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat gaagaaatga
    19501 aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca ccttacgcca
    19561 atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc ctgaacagat
    19621 ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag acaatattga
    19681 ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc cagtagccaa
    19741 tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac tcgatagata
    19801 tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga cgcgtcaaat
    19861 cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg gtttgatatc
    19921 ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa aaggtctggt
    19981 tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc atattttgtc
    20041 tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt ctgctgccaa
    20101 aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga ttgaaccgaa
    20161 tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg ggattcctgt
    20221 agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt tcttttattc
    20281 ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag tatttgtacc
    20341 tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc ctgcgggtgt
    20401 ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta acggaccgat
    20461 cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta tccaatgggc
    20521 tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa tcgttccgtt
    20581 gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc tgcgaagtaa
    20641 acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac ttgcgggagt
    20701 gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg ttgctgcttg
    20761 cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag cgatcgcttt
    20821 tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt tctggtactt
    20881 agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta gcgggtttga
    20941 tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag atgtttatca
    21001 catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt gatactttcc
    21061 aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt tatccccaaa
    21121 caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg ctcgttgctt
    21181 atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa aagcttttcg
    21241 acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga aaatcaatga
    21301 aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct agctgctact
    21361 tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga taatcaaata
    21421 gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag tgaaacaacg
    21481 gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc gaccgagcca
    21541 actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac atattccctt
    21601 acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc ggattcccct
    21661 gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt agcggaaacg
    21721 aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt cgctgttaat
    21781 ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa caatttatct
    21841 attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac tgatcctagt
    21901 gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt gggtaataac
    21961 aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa cagcgggaat
    22021 tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca gagagaacca
    22081 aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc tcgtccaaat
    22141 acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt tgttgtaaaa
    22201 tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc aatcgttcga
    22261 gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc aaatactttt
    22321 gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta tatcggtggc
    22381 tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc ccaacctggc
    22441 gacctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat ctatattggg
    22501 aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac ttctatttca
    22561 gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc tgcttcaggt
    22621 tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca tttcagtcaa
    22681 aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga aatcgggcaa
    22741 aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag tggatctgga
    22801 aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg atcatataaa
    22861 ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag ctaccaaatc
    22921 cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta tgccgacttg
    22981 atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa gtcggaaaca
    23041 aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga tcgccaatat
    23101 tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga tgaaccgaaa
    23161 aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc taagcgattc
    23221 gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga attttcaacg
    23281 ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg ggatttgtgg
    23341 aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa agctgcaact
    23401 gttcctgtac taaccttgtt aagtttagac aaatcattct ggcttgatct gcctttaaag
    23461 aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta atttattcta
    23521 tttctttata tttattttgt attccgttac aaactcgcgt acttggttag gttccagagt
    23581 gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct caaatgtgat
    23641 accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc caaaatttgc
    23701 tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt tttcatctgg
    23761 gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa atggatgatc
    23821 gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac ctaatttttt
    23881 aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg taggcgttgt
    23941 atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt cgtcgattga
    24001 ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga atactgtttt
    24061 gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca gcgtataccg
    24121 tacttctaca tctaaagttc caggaaatcc gttttccata tctgggctag tctgatagaa
    24181 aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct tggcttcaaa
    24241 gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta cttcgaacgt
    24301 ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc cgattgaagc
    24361 accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta agatcaactc
    24421 tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa gatcactgac
    24481 agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt cgccaaaatt
    24541 ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac tgattccagt
    24601 atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa aatttactat
    24661 attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca acctcttttt
    24721 ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat
    24781 atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc tttttcacaa
    24841 tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt agatgaaata
    24901 caatacgaag aatatcgtaa acggaaccca aatatctttg tatggatttt gcatgaatag
    24961 accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg gtgctaagaa
    25021 taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg ttcctatctt
    25081 ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct tgaacatcaa
    25141 acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa attcaaaacc
    25201 agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt actctacttt
    25261 ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg gtttcaggtt
    25321 tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt tcagttgatc
    25381 aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca attcatagct
    25441 tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt tttctttcgt
    25501 gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag ccgcaaattc
    25561 acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag cagaaagtgt
    25621 tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca tcactagatc
    25681 atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta atcctaccgt
    25741 caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt gtgtatattc
    25801 acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca atgaaatctg
    25861 ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa tgaaataagt
    25921 tcctaatacg atcgtaacta aggctacccc tataccaaag acttgatagg tccccacgtg
    25981 tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt caaggaaaaa
    26041 caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca atgctaaaat
    26101 cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca aaacagcaaa
    26161 aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg aaatattgag
    26221 atctaactga tccactaata atcggtggac gatacttgtc aatcctacac cgacagctga
    26281 acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca tctgtgcgat
    26341 ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc gcatcgtcat
    26401 caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta aaacagaacc
    26461 gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa aagcttcgtt
    26521 gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc ctgagaataa
    26581 caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc aaagcatagt
    26641 caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga tagaaggaat
    26701 cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg atgaataaaa
    26761 tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc gatacatgat
    26821 cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg gaatccagcg
    26881 cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca cgtgcggcgg
    26941 cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa atatgagaga
    27001 tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt ctgacgcctt
    27061 gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat aaattgaaat
    27121 cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt ccttttaatg
    27181 tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct aatgtggata
    27241 aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca ataaattcgc
    27301 ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca ttgttttttc
    27361 cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc cctacccttt
    27421 aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt catacgaagt
    27481 gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa gcggtcgagt
    27541 caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc caggcaggat
    27601 atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt ttgtaccatc
    27661 tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg cgattttcac
    27721 ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt tcactttttc
    27781 cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct gccttcgaat
    27841 caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa aaagagttca
    27901 agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt cacttacggt
    27961 ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg attgagacaa
    28021 gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct tgtccatctt
    28081 cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg gtttgtcgag
    28141 cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt tctgttgcat
    28201 aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct aaacgctctt
    28261 gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc gtcaaatcat
    28321 tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct gtctcacttt
    28381 ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct gtatcaacga
    28441 ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca ttgactttta
    28501 aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt gccaaaggta
    28561 tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa aacaaaatta
    28621 cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac gtgatcaacc
    28681 aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct aaatagaaga
    28741 aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa ccattgatat
    28801 aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca ataaatatct
    28861 aatgttactt ttttaatttt tttttcgaat acgcgccatt acaccttcta gttctaactc
    28921 tttgtcttca gtgatgtacc aaccgcttgc ctgtgtccct ccggctgcct gcggtaaata
    28981 atccaatttt gttcgaaccc agtgcttttc ttctgtaaaa tagtcttcta ccaagacctc
    29041 tagatccatc cctgctgaaa gaggcaaatc ttcccgaaca gatttaaaga taaatcgttc
    29101 cttcttccca tcatacttca atattcctgt atcgataatc ggtaaagaat aataatccag
    29161 ctctttcttc accgtcaata aatgtttgaa aacttcatgg tacacttgct ctaattggcg
    29221 accttctgaa ttgttcgggt aattaaccat cactttttct ttgtctggat catagaaggt
    29281 ttggcttagt tgagtgatat aagtatgtaa tctttccatt tctgttttta acttttctct
    29341 ttgaccttct tctaccttca tatactcttt caccctgttt tctttttaga tattttcttt
    29401 cttattttac tatagttatg tgcgttaagc gatgaaaaac agcaaagatt ggaaggatct
    29461 ttgctgtttt ttcttaaaat atccagttga gtacaggatc aatctgtttc attgtcctct
    29521 tgatccgtcg taatattgat cgatgtgtct ttagcagtga tctttagctt tttctgtcct
    29581 tgttctaaca aagtatttgt tattggctgg tagtcttttt caatataaga ttcaccagac
    29641 gtttggatag tatagccact gttttccatc tcatgcaaag ataaattgcc accgtttagg
    29701 atgacttttc cttctttgct gatcaaactg tcttctagat ggaagttgct gttttcacct
    29761 gtgacgatca agttatccac attggcctca tctaatcgaa gtgagcctaa ttcatctttc
    29821 gcagttattg ttcctcctgt aaattcattg aacgataccc agccatcatg tgtcttagta
    29881 ttcacttttt tgattgatac ttcgttgata tcaattgcac tattattccc ttcgattgtc
    29941 aattcagata attcatgatc tgcagggaca acaatagtga tttgtgcact tgtgtcttct
    30001 aaactaatga ttgcacctgt tgattttttg actgcattca cagtcaacac gccatttttc
    30061 tcctttattt ctggcttttc tgtcttatca taagtcgttt ttatctcaaa atccaatccg
    30121 cgtatgaccg aaactgtttg attttctgca tggatgacga ttttgtttgc atccttgatt
    30181 ttttttgtct cagtaaccat atcgatcaac cgaggaccat tatcccaagt cagactcttt
    30241 tgagcgccta atgtataagt tgcacctgct aggaggccac cagtaagcat cagaccaata
    30301 ccggtaatca aaaaatgttt caatctcaat ttatgtgtcc tccttcaaac gcccgctgaa
    30361 tgcagatctc tttttgtaat aaaacgtcgt cccatccatt taacaaagtt catcatgaca
    30421 taaaaaagcc cttttgttcc tttcagcaac agtggcgaaa taaatactgc gcttcctgtg
    30481 gcgaacagac cgacaccgat aaagaataat ccactcagaa tcgattgtcc aaacacactg
    30541 attcctgaga tgatcatgaa taggccaaca cctaagatac tgatacataa aacatagata
    30601 ctaaaaatga gcgctagtaa agcaaccaat agtcccccaa taaccaatat aaaccccagt
    30661 gctagtggaa tgaggacagg agaagcaaat aaaccgataa tgattaacca aatcaggcga
    30721 atttgtcttt ttggattttt cactaactcg ttttctgctt gttcttcttc tgaaaagtaa
    30781 ctgattttta attttaaggc aaactgcttt ggtgtaccat attcatcaat gatctgatct
    30841 aatgtttttc cagaatctaa aaaatattcc tcataatact ggatcaaatc aaaacgatcg
    30901 tcttcaggaa tttcttgaag atgatccaca acttcattca aatattcatt catttgtgct
    30961 ctcctccaat aaccggtcta aagaatctcg aaaaacaatc cattcatcaa taatttcttc
    31021 taaatgacga cttcccattg gtgtcaacga gtaatatcga cggtttctgc cttcaaaagg
    31081 ttcatcatag gtctcaagat atccttcttt tttcaatctt ctcaaaaccg gatatagtgt
    31141 agattcactg acagagagac tttcttgtac gatttttgtt aaggcatacc catacatatc
    31201 ttccttgctt aatgctgcta gcacagtacc atcaagaaga acagttggaa tctggatgtg
    31261 cattacgtca ccttctattc tcaagtgtaa tattttattt caatctatat tatacaacat
    31321 ataatatagt ttcaaaatca gtttgtcaaa tacaaaaaaa ctgactaaaa gatttgatcc
    31381 tttttagtca gcaaaaaatg gcttctcttt gatttttatt ataacagtgg cataatccaa
    31441 tttgtccaca tccagctcag tggcatgata acgatcattg caggtatcat gtcagctact
    31501 gggaacattt tcacgttgat cattctaaaa ccggtagcga ccatcaagaa tccgccgcaa
    31561 gctttaaaat ctaagatcat gtctggtgta gtcaatggat aaataaattt tgccaataag
    31621 aacaaaatat aaaaaataat gaattgggga attgctatca cagaaacgac ataccctaaa
    31681 ttacacgcaa aaatagctgc tgtgaaaaaa tcaaggacag atttagaaat caaaatcgta
    31741 ctgtctcctg tcatcccaga atctaaactt ccatagatcc ccgtaccact tgcacaaaat
    31801 agaacaatga ccgtcactaa tgtgctgata aattcatcgt gggtcatacc aagcttttca
    31861 ctagggaaga ttttagaaat aggtacttgc atcagcgcag cccccttatt tatcccatta
    31921 cctaaatgaa caatcaaacc aatcgctgtt cctatcacta aagcaaaaat aacagccggc
    31981 atatttttca tcggcgcaat ggaatagatt cccatcccca tcgaacacac accaaaaacc
    32041 atcgtcagct gtgctttaaa atgttcactt aatttatttc ctactaatcc gccaattagt
    32101 ccgccaaaca aaacggaacc tacattgatc aaaactccag ttggcatcaa aaaactcctc
    32161 tctttttcta cgaagcgaaa aaaatcagaa aaatttctgt aattattgct ttcgctgcaa
    32221 gaaagattgt aacagacaga gaagattaca ccaattcatt ttttgtgtta aagtattctt
    32281 tattggaata agtaggagga atatgatgga tatccataaa ttcgaagttt ttcttgattt
    32341 agccgaaaca atgaatttca ccaaaactgc tgatcgacaa ttcaccaccc aaggaaatat
    32401 ttctaaacag attctttcgt tagaaacaga attagacgtc aaattattcg aacgcgccca
    32461 tagaaaaatc gaattgaccg aagctggaag cttattgctc ccatatgtaa aaaatgtcgt
    32521 agaacaatac catgctatgc aagaagtgct tgaaacctat acgaaagaca acaatctttc
    32581 attaaatatc ttaacgatac cgacaatgat caattataaa ggtttttcca aaatcaccga
    32641 gtttttgaaa cgccatcctg aatttacagt ccagttgaaa gaagtggaaa gtgtcgaatt
    32701 aacttacaat gacgccaatg aacatagtga cacgatccac tttgctagaa gtttccaggc
    32761 cccaccaagt tcgattgagt ggttgcctac tgaaacagac gattttgtag cagttctacc
    32821 taaaaatcat cctttagcta gtaaaaagaa attggatcta agcgaactga aaaaggagaa
    32881 ctttttgctc cttggcccca ctacgaactt gtatcaacct gtactagatc tgtgtcgcga
    32941 agctggattt gaaccaaaaa tctcttataa aggagcaaga atcgacttga tcatcaatat
    33001 gattgcaaat gacatgggga ttgctattgt tatggaaaaa acagtcaaga atctattaaa
    33061 agaaaatact gtgattctcc ctatttctcc aacaacagag agttatcttg catttactcg
    33121 taaagtcggt gagcattctt tggcttcaga tacattttgg gagtatttaa atcaagaaga
    33181 aaactaagcc ctacattttc tgtccatcta tccacccaaa aaaagagagc gacgcatgac
    33241 tttcgctctc tttcttgcat catgtccttg tttcaatgac acctctaaca tttctcgtag
    33301 ttcaataaga aagcagcgat ttttatgcca aaagaaccgt aagaacattt ccctaatcac
    33361 aaaaaaacga ctaaaaaccc ctaaaaacct tcaatagaat ttttaggggt tttattcttt
    33421 ttcctattgt ttacttaacc gtatcattgc tgtcgttcct actccttcga tactgctata
    33481 atcaatacgt ccatcatgca gttctagaat ttttttaacc agtgaaagtc ctagcccatt
    33541 cccagaaatt tgacgacttg tatctccttg ataaaatttt tcaaacattc gatctctggt
    33601 ctcttcattc attcctacac ctgaatcggt cacttccagt acaatctctg tggctgtctc
    33661 aaatagtttg atatgaatct gtccattgat ttgattgtac tttatggcgt tatccatgat
    33721 attcagccac acttggtaca aaaactcttc attgcctgtg taatttactg cagcaagttc
    33781 gatatccaat tctagctgtt ctttctccca tttaggctga aaaaaaacga ttacttctct
    33841 gatttgttca tctaatcgat actctttctt ttccagttgg atacgctggt tttccagttt
    33901 gttcaatttt aagatgttct ctgttaattg tgaaagctgc gtgatacttt cgataatccg
    33961 atataaaaat atttggcgtt cttcgtcaga gagatttggg gcttgtaaca attgaacata
    34021 tccttggatt gttgctagtg gtgttttgaa ttcatgggat acactggaca caaagtcatt
    34081 cctcagtgtc tcgatactat tgagttcttg gaccataacg ttgaaatctt tatacagttg
    34141 ctgtacttct gctactttct gctgttcatc cattcgaatc gaaaaatctc ccgttgctac
    34201 cagactcata tttgtcccta gcgcactgat tggatgcagg atacgccgcc caacaaaaat
    34261 cgatattcct gtacccacga ccatactgaa ccccgcaaag acgaataacg ggtataacgt
    34321 tggttttcca gccgattcag caggcgagat agaatgtcga gacaataaga aaataaaacc
    34381 gagaaaacac agcagtgtca ctaagatcga aatgaagaca atactagcaa aatagatcca
    34441 taattgtgaa aatagctttt ttttcatctt taaataaccg ccttatagcc tagtccccgt
    34501 actgtgatga tttgaaaatc ttccgtcttt tcaaaacggg tccttaaacg tttgatatgt
    34561 acatcgatcg ttcgttcttc tgtattcgta tctaatcccc aaatatcatc catcaactgt
    34621 tggcgagtga agatcttgtt gggataagac agtaatttat acagaagcag aaattctttt
    34681 tgaggcagaa tcaacgaatg ctgatcttgt aacactgtat aagcatctag ctctaatttt
    34741 gtttgtccga ttatcaagct actgctgtaa ttgatctttg aacgtcgaag caatgcttcc
    34801 acacgtagga tcatctcatt gacatcgatg ggttttgtca tataatcatc tgctcctaat
    34861 ttgaacccgc gtttcttatc ctcaaaatcg gcctttgccg taatcattag aacaggtgtg
    34921 tcaaatctgg tgctacgtaa tgagtctagc aagtcatagc catccatttt cggcatcatg
    34981 atatctgtaa tgattaattc tatacgtgtc gcttctagtt ttttcagcgc atcctctcca
    35041 ttcaatgcgg tgatgactga aaagcccgct cgttccaaca cagaacggta aagcaactgt
    35101 aattgcggat catcttctac tactaaaata cgattcattg atctccctct gttttttgaa
    35161 aaatttctag attttttctt gtagttcatc ttcagttaac atttatttcg tatactacga
    35221 tcattgttct gatatactta ttagtatacc gaatatttca atacgggaga agggtgatta
    35281 tgcttcaatt aaaagatata aaaaaatatt ataaagtcgg cgaaaccacc accaaagcat
    35341 tggatggtgt gtctgtcgct ttcagacaaa aagaattcgt agcgatttta ggtcctagtg
    35401 gttctggtaa aacgactatg ctgaatgtga ttggtggact agataattat gattccggtg
    35461 atatggtaat caacggaaag tctactaaag actttaagga cagtgactgg gatgcctacc
    35521 gaaacaactc tatcggtttc atttttcaaa gttacaactt gattggtcat ctaggcatta
    35581 ttgaaaacgt tgaacttggg atgacattaa gtggtgtttc taaagacgaa aaacgaaaac
    35641 gggcagaaga tgcattgcac cgagtcggct tgacaaatca tatgcataaa aagccaaatc
    35701 agttatctgg tggacaaatg cagcgagtgg ccatcgctcg agcactagcc aatgacccag
    35761 atatcctttt gtgcgatgaa ccaaccggag cgttagatac agaaacaagt atccagatca
    35821 tggaattgat ccaagagtta tcgaaagaaa aattagtgat catggtcaca cataatcctg
    35881 aactggccca tcaatacgca gatcgaatca ttgaattttc tgatggtaag atcttaacag
    35941 attcccatcc tcacatcgaa cgaccaaaag atgatcaatt taacttacgc agaacaaaga
    36001 tgagtttttg gacagcgtta aagctttcct tcaacaatat ccgaacaaaa aaaggacgta
    36061 ctttcttgac ctcctttgct tccagtattg ggatcatcgg aatcgcgatc gttctgtccc
    36121 tttcttctgg attccaaaaa caaatcgata acacgcaagc tgaaacgatg gcgaaatttc
    36181 cgattactat ttctaaggta acgactaacc agactcgtga cgatgccgga ttgggtgcaa
    36241 gcaaagcgga ttatccagac agcaaaacga ttactgcaaa agtcagcgaa gaagataaag
    36301 cacagcacac gaataagatt gatcaaacat acgtcgatta cgtaacagac atcgatccta
    36361 acttaagtaa taatatcgga tttacccgta ctacaggaat caatctttta cgtgatgtaa
    36421 atggcaaagt acagcctgtc agcttctcga atcaaaatcc tgatacggaa tctctttctt
    36481 tatctagtac gatgtcagca atgacaggtg tgggagtgtc aagtttccct acacagcttg
    36541 acactagcaa agaaaacttt ttaaaagaca attattcttt acttgccgga agttatccag
    36601 cctcagcaac agatgtcgtg ctgatcgtag acggcaataa taatactaat atcaacgcat
    36661 tgaagaatct tggatttgat gtgaaagaag acgaaaaact tgattttgat gatatcgttg
    36721 gtacaacatt caaattagta aacaacaata cttactatac aaaacttcca actgggaatt
    36781 ttatccctaa tacagattat gatgcgatgt atcagaatgc ttctgatgaa ttgaagatct
    36841 cggggatcct acgcgtgaaa tcttcttcta caatgaatct cttatctcca ggaatcgctt
    36901 atagcgatca attaacgact caaatcgtca acgaaaacaa agaatcagaa atcgtcaaag
    36961 ctcaaagaga cagtggtgta aatgtcttaa ctactgaaaa agttgacgaa aatgccaaac
    37021 aaacattgct tagttattta ggtggagaca gcttgccttc aagtatcatg atttatccga
    37081 acaattttga agacaaagaa aagatcttgg attatctaga tgattacaat aaaggcaaat
    37141 cagatgaaga taaaatcatt tatactgatt tagctggaac gatgactgaa ctgactggcg
    37201 gattgatgga tgctatcact tatgtcctta ttgcttttgc agggatctct ttagtaacaa
    37261 gtatgatcat gatcagtatc attacttata catctgtgat tgaacggaca aaagaaatcg
    37321 gtgtactaaa agctttaggt gcacgtaaaa aagacatcac tcgcgtattt gacgcagaaa
    37381 cgtgtatttt aggtatttct tctgggatat taggtgtgtt tattgcatgg ctagctacgt
    37441 tccctatcaa tagcatctta tacaacatga cggatctaaa aaatgttgct caactaaatc
    37501 ctgtccatgc gattattcta gtgatcgtct ctactatatt gacgatgctt ggcggtcatc
    37561 ttcctgcacg aatggcagcg aaaaaagacg ccgctatcgc tttgcgtgca gaataaggtt
    37621 gtgacaacca catttagatt tgagtcataa gagcgctgaa atagtagaaa acagcaagaa
    37681 acgaggaagt aatatgttcc ttgtttcgcg ctgttttttt ttaattattt tttataattc
    37741 tggtatactt ttctttcctt tgtaccacaa ctcttctggc gtatacctgt cttttccatt
    37801 tatgaatact gttccatctg cttcaatcgt tacttcagtc ccaatccaca tattacgaga
    37861 aagtgcgaga agattttttc tttttcctct tccttttttt ccaaattgca aggcatcggt
    37921 tatctcttct gtccaatgag atttcacgta ttttacttct ccgttttcaa atgtaacttt
    37981 caaaatattc gctatatttt ccacttttac tgctttagga aatgactcct ccattttttt
    38041 cactttcctt cctccaacac taagtatgcg ctttctttta gtgataagta tatcatagtt
    38101 tattctatta tcaaaaaaac gcatccattc cattgtagaa tactttaccg aacaagttga
    38161 attgttttcc tctttttcac cttttactat agataggtaa agacaactaa ggaggaatct
    38221 ctcatgacag atcaaccgta tgatttaaga aaagtcatcg aagaactaaa aacacttcca
    38281 ggtcaatatc acgaaacaga tattgaaatc gatcctgaag cagaattatc tggtgtttac
    38341 cgttatatcg gtgctggcgg tacagtaaaa cgtccgactc aagaaggacc agctatgact
    38401 ttcaacaata tcaaaggttt ccccggcaca cgtgtgaaca tcggaacaat ggctagtcgt
    38461 aaacgtgtag gtgaaatttt gcaccatgat tatcgaacac ttggtcgttt cttgaaagac
    38521 gctgtagaaa atccaatcaa acctgtgaaa gtagacaaag cagacgctcc agcacaagaa
    38581 gtcgttcatc tagctaccga tgcagacttc gatattcgca acattttgcc tgcacctaca
    38641 aatactcctg aagatgctgg tccatacatc acaatgggtg tagtcttagg atcagatcca
    38701 gaaaaaacaa tgagcgatgt aacgatccat cgtatggttc tagaagataa agatacgatc
    38761 ggtatgtaca tcatgcctgg cggacgccac attggtcact tccaaaaaca attcgaagcc
    38821 ttgaataaac caatgcctat cactatcaat attggtttag atccagcaat tgccattggc
    38881 acgactttcg aaccacctac cactccactt ggctacaatg aactatggtg tgcaggagct
    38941 ttgcgtaacg aacctattca aatcgttgat ggtatagcag tcgatgaagt gggtattgct
    39001 cgtgctgaat tcatcattga agcagaaatc atgccaaatg aaacaatgca agaagatatc
    39061 aacacgaact caggaaaagc aatgccagaa tttcctggct atactgggga tgctaatcca
    39121 gctgtacaag tagtgaaagt caaagcagtt actcaccgaa aagacaatcc aatcatgcaa
    39181 acaacgattg gtcccagtga agaacacgta tctatggccg gtattcctac agaagcaagt
    39241 attcttgcct tggtcgataa agctattcca ggaaaagtag taaatgtcta caatcctcct
    39301 gcaggtggtg gtaaattgat gaccatcatg caaatccgta aagaaaacga agcggatgaa
    39361 ggtattcagc gtcaagcagc tattcttgct ttatcagcct tcaaagaatt gaagacagtc
    39421 attttagtcg atgaagatgt tgatattttc gacatgaacg atgtagtttg gactttcaac
    39481 actcgtttcc aaggagataa agatatcatc gtgatcccag gaatgaggaa ccatccattg
    39541 gacccatcag aattaccaga atataatcct ggctctattc gtttccgtgg gataagtgca
    39601 aaaactatct ttgacggtac agttcctttc gatatgaaag aacattttgt acgtgcaaaa
    39661 ttccaagaag tagaagattg ggaaaaatat ttgaaataat gaatgatctg caactgtttt
    39721 gacatcataa aaaggagtgc ggaaaatgga acaattggca caacggaaga aaaaaatcgt
    39781 gattggtgta agtggcgctt caggcaccat ttatgccatc aacctagtga agaaactaaa
    39841 agaatatccg atgatagaaa cacacggaat catcagtcca tgggcaaaac agaacttaaa
    39901 gctggaatcc gacttatcac taactgaatt cgaaagcctg tttgattacc attattcaaa
    39961 caaagattta ggtgctgctg tcgccagcgg atcatttttg accgatggaa tgatcatcgt
    40021 accggcaagt atgaaaacag tcgcaggtat ctctgttggt ttaggcgaca acctgattgc
    40081 acgtgctgct gatgtaacaa tgaaggagca acgaaagtta gtcattgttc ctcgtgaaac
    40141 gccattaaat gccattcact tggaaaactt gactaaatta gcacgactag gtgtgcaaat
    40201 cataccacca attcctgctt tttataatca gcctcaaacg atccaagatc ttgttaatca
    40261 ccatacaatg aaacttttgg atcaatttga aattgtaaat gagcattcaa aacgttggca
    40321 gggtgattaa tatggaaaaa gaaacgatag ttgaagtaac caaactaggt ttcacgatcc
    40381 aagctgctgt taaagtaatc ggtaaagact tattgatcac tttaacaggc ggagatacac
    40441 cacatatcgg aacagtcact acattttctc gtgatacaga gatgcaaact gtacgtttcc
    40501 ctagccacga tggtcggttc cataaagacg atgtcttagc cgaaaaaata gctgtgatca
    40561 tcaaaactgc cgttccggga agttgtacga tcacttccgg tatccatgtt gaccatatct
    40621 ccaatgcaca aatcaacgcc tcttttccga tgtcagaaga gttaggttac aagattttag
    40681 attggttgga aaaaatagat ttccatatca aagaaccagt ttattataaa gatggtgaaa
    40741 aaccattatg aaagaagagg ttgtgaaatc agcgttatga cctgagtatg agagaaaaaa
    40801 atggaaaaat agcttctcat attttgccgt ttttgagcta ataccgaggg acagctgatt
    40861 gaacgccgtt tatcaagagg ttgtgataaa gccgcttcgt ttcgagtagt aagaaaaatt
    40921 ttgtaaacat gggtttccac atttttgcat aaatttgact tactaccgag aaactggctt
    40981 ttgaacaccg tttatcaaga ggttgtgaca cgtcttttgt cacaacctct tttatttttg
    41041 cttcactgta actgctacaa tatcaccgat ttcttttccg atgtttttac gaatatcttt
    41101 tcgtagtcca aggatgtagc agactgaacc atctggattt ttcacgccca tattcacgat
    41161 actgccttca tacggcacat tgtcaaaagt tgcttggact ttaactcttc cagcaccgaa
    41221 ttcttttctt atatcatacg gaaaaataat atatgccccg cccttgccga cttcggaagc
    41281 atagattttt gattcaaaag aataaatttc cctcatttta tttctcctat tttttacatc
    41341 tagtatagca tagcaaaaaa aagaaggaac tgtgacaaaa gtcttgtcgc agttcctttt
    41401 ttcgaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata gtcaacaaac
    41461 atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc aggctcacaa
    41521 cctcttcctt aaacggtgtt caaaatatta ttcgcctttt gcttctttca ctaattttgc
    41581 gaatgcttgt tgttggaatt cagcagctaa ggctttcgta cgttgttctt gctctgcttt
    41641 gctcattttt ggattttcag tcattgcttt taccataccg tcttgaacat aagcttttgc
    41701 ttcactttcc atcgtacttt gctgtttctt cactaattca gctaacttgg ctgcttggtc
    41761 cgtacttaat tctacccatg tctctgggat tttgaatgta ttcactcggc tgtcatattc
    41821 gtgattgtta tcagcaatat tgaaccagaa tttatacatg tcgtttttgt attcccaata
    41881 agtagttttc gtcacttttt cagcatcgcc gtctgtcttt tctactttat ttgtttcgtt
    41941 atccgtacca gttgcttttg gtttttcttg tttttcattt gttcggtaaa gatacacttt
    42001 ttcttttcca ttccctaaag ctttatacaa aagcatatct gctccttggg aatcagcact
    42061 ggaaacaatt ttttctgttt ttgtttccgt tactttttcc attccaaagt gattggacaa
    42121 attagcgacg atcaaactta gtgaagcgac gaagattagt ccgaaaatca aagataaaaa
    42181 ggtttgccat gtttttttag cgaacacgtt cgttaaagca aaagcaagca agctgacaat
    42241 caaaactcca ataatcatgc attatccccc gctttcatta gaacaggttc ttttttcttc
    42301 aataaaaagg caataataaa gccaagaatc ccaaagatga tcgctacgat aaacgcggca
    42361 tggtaacctg acagtgtggc attgattgcc tgatctttat aagctaatgg cgtattatcc
    42421 aatacagatt tgcttgggat atttgctttt gtcacattcg tcaacacact gatcaaaata
    42481 gctgtaccaa tcgagcttgc gatttgacgg aatgtattat ttaccgctgt cccatgactg
    42541 atcaagttat ttggcaatgc attcatacca gaagtcgtta ccggcatcat gaccatggag
    42601 atcccaaaca tacggatcgc ataaaggatc acgatatata aaactggagt cgtttttgtc
    42661 aagaaagcaa atggtgcagt tgccgctgtc aaaatgaaca tccctgtgat ggctaaacgt
    42721 ttcgcgccgt atttatcgaa aatcgcaccc gtcacaggca tcatagcccc catgatcaat
    42781 gcacccggca acaacatcaa gccagaatgg aatgctgatt ctccacgaat attttgaata
    42841 tacaatggta cgaccatttc tgcccctacc atcgccatat ttgttacacc agctaaaaca
    42901 gctgcaatcg tgaatgtaga tgatttgaat acacgaagtt ccaagaatgg atgttccaaa
    42961 tgtaattgac gccatgagaa caaggcgatg aaaatcacac caacaactaa gaaaccaatt
    43021 actttcaagc ttccccagcc gtcatctcct acactagaaa atccgtaaag taaactaccg
    43081 aatccaatcg ttgataaaat agcggataaa atatcaatgc taggatttga caatggaata
    43141 acacttttca ttaggaagaa tgctaaaacc aagacaagaa caacgattgg cagtaccata
    43201 ccaaacaagt cacgccaatg gtagttatca atgatataac cagataatgt agggcctaaa
    43261 gcaggagcaa gtccaataac gatccctgac atccccattg ctgatcctct tttttctggc
    43321 gggaaaatag atagcatgat attttgcaat aatggcatcg atactcccac accgcaagct
    43381 tggatcaaac gaccgattag taatgtacta aaattaggtg ctgtaaagca agtaatcgtt
    43441 ccgatcaaaa agatcgtcat ggcagaaaga tataaatttc ttgaactgaa tttattgatc
    43501 agccatgctg ttattgggat catgatcccg ttgactagca agaaaccagt cgttaaccat
    43561 tgcacatcag acgctgaaat atcgaaagct ttcatcaatg taggaaaagc tgtcgtcaat
    43621 aaggtctgat tcaaaacggt acaaaatgta ccaattaata agacaacaac taaaagtgtc
    43681 cgattatatg gttttccgta aatatctacg ggttggttgt tactcatatt tctccttctt
    43741 tctgaatttt ttctgaaact actagaatac tttagtccta aattcgctat ttgtcaacct
    43801 acttgacaca taagttaata cggatataat taagggaagc aagaggacaa aaggagtgac
    43861 aaaaatggtt ggggcttccc ttaaacgttt gttggaaaat gatcaattgg ttgttggcat
    43921 cagtgaatta agtgatatcg taggtgtgtc tccacgtcaa ttaaggtatt gggaacaaaa
    43981 gggattcatt cgttcgatcg aagctgatgc gaattgtcct agaaaatatc gtttacctac
    44041 agtcataaaa gtagaactga tcaaaaaata tttagatgac ggatttactt tgtcaaaagc
    44101 tgcagaaaag gcagaaatcc gccaaaagaa aatgcaccat gtccgtaaag ttttttcaaa
    44161 agcaatcaaa gatatcgaat tgatcgacga acgctatacg attttacaaa tcggtaactt
    44221 caaagaagag aatgctaaga tgtacatcat tcatgacaac gagacagacg aattaactta
    44281 caagctcctt cctgtcgatg aaaaagctga ctacgaacag ttgttaaaag aactctaaac
    44341 gccactaatc tcctaagtac caagcttttt aataagtaga tgctacataa atacttgaaa
    44401 aaaggcctgt ttgaacataa gaatatccga acggtgatct gcgtttcttt catatagaaa
    44461 ggaattctcc atcactgttc ggatattttt ttattttttt cggttacttt cttctaatac
    44521 atctgttagc caatttgcat attctgtttc ccgattgatc gcatgcgcta aaatcaggta
    44581 gtgtccgtaa ttttcatgtt tttctttttc agtaggaaag atcgtttttt ttcgctctaa
    44641 tagatgaagt cgtttttctt catgaaggtc acgctgctgc tgaataattt ctactaatgc
    44701 cggatcattc acgtctttga cgaaatacaa tttcagaaca aattcgtctc gattaaccgg
    44761 tagttcattg gtgggtgtat gaatccactc tgccaattgt tccttccctt cttctgttaa
    44821 ttcataaact ttcttttcca atttttcacc tgtgatctct acttgatgct gaatgattcc
    44881 ttgctcttcc atttttgcaa gttcaggata aatctgacta tgttttgctt gccaaaattc
    44941 tcctatttca tttttgaacg attgattcaa ttcatatcct gtcatcttct tcttacttaa
    45001 taaccctaac aaaatatatc gaagtgtatt ttttcttgcc atcagttttc cctccttgac
    45061 aaatctttaa atccattcta tcataaatga gtaatcgaaa acatgtagtt tattacatgt
    45121 tttaatttat aaggagatgc ttaaacatga aagaatttaa agaattggaa gattttattg
    45181 gaactcactt tatctatacg tatgacaatg gttgggaata tgaatggtat gccaaaaatg
    45241 accatactgt tgattaccgt atccatggcg gaatggtcaa aggccgttgg gtaaaagacc
    45301 aagaagctga tatcgttaaa ttgacggacg gcgtattcaa aatcacttgg acagagccaa
    45361 cagggacaga cgtggcattg gactttatgc caaatgaaaa gaaacttcac ggaatgatct
    45421 ttttccctaa atgggttgaa gaacatccag aaatcactgt tactttccaa aacgaacata
    45481 tcgcagaaat ggaagcagct cgtgaaaaat atgaaactta tccaaaatta cttgttcctg
    45541 aatttgctac gatcacttat atgggtgatg caggtataga caatgaagat gttattagcg
    45601 aagaaccata cgatggaatg ccagatgata tccgtagcgg aaaatacttc gatgaaaatt
    45661 ataaacgagt aaaataaggt tgtgaaagag aggttgtgaa atcagcgttc tgacctgagt
    45721 attagagaaa gaaacggaaa aatagttcct catgttttgc cgttttttga gctaataccg
    45781 agggtcagct gattgaacac cgtttatcaa gaggttgtga aatcagcgtt atgctttgag
    45841 taataagaac gctagttaga aaatagcttt tcatattttc taggctagtg ggcttattac
    45901 cgagaagcag ccgtttgaac accgtttatc aagaggttgt gaaatcagcg ttttgacctg
    45961 agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt tgagctaata
    46021 ccgagggtca gctgattgaa caccgtttat caaagattgt aacaactgca tattcacaca
    46081 gttaaattag tgacttcaaa atgaaataat gctcccagca aaaaattagg ctgggagcat
    46141 tatttcgtta ttctgttcat caaaaatcag cgttttgatt ccatttcatc acaagttcct
    46201 cctcatttac tgcttcatct ttttgctgtg tttgaattgt aaaaccttgt gaaagataga
    46261 aatgaatagc tgattgattt ttttgataga ctgtcaaagt cagtgtttta ttggtttctt
    46321 ttattttttt cattagttgc gtaccgattc tttgttgccg gtattccctt ttcacaaaga
    46381 ttcctgcgat aaactgatca atcaccccag caaaaccaat aatttcttga tctatttctg
    46441 ctaagtaaat cactgcatct ggtaaagctt tcctaacaga ttctacttga ttctcccaat
    46501 aagttgatgg aatgaattca tgagaatcca agttagcatg cagccaaatc gatagaacag
    46561 attccagttc tttggcagac aattttgttg ttgtgcggat cattttttct ctccttactt
    46621 attcattgat tttaaaataa aaaccatttt tttgaagctc ttttacaagt tttcgcccct
    46681 caaaaaagta tatcttctct tgttttactt ttctaatacc aaaagaaaca gcaactttag
    46741 gatcatcagc tgaaacgatt cgataagttc caccaggcaa ttgatccagc ttgactttcc
    46801 catgatggtc gctttgtact gaaaacggca caccatttct agtaagtgtt tttttcttat
    46861 gtttcaaaat gaatgaacta ccatttaccg gtttccctga cgaatcacta ataataaatg
    46921 aaaaatcaag cactttttta cttaatctat actgatagat tagtcgtccg ataaacacta
    46981 acagtatgac tacagctatt atcgttcctg caagaataaa ccattgccgc atggttcttt
    47041 cctgatttcc ttttccttct tcttttttta ccgattcgtt ataaggaatc cgatgtcctg
    47101 tcactagcaa acgatgcgtg ttgatcatat acggcgtaca tgtaagcaag gtaactaagt
    47161 cttctccttc tgaaatcgtt agaacagacg tgtcatctgg cagtaccact tgtatatttt
    47221 taacttgata agccaatttc tcccccaaaa cagtcaaaat aaacgtgtct ccgttttcta
    47281 aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc gctgtgagca gagatcactg
    47341 aatgcgtcga atttccacca agcgggaaag aggttccttg caagacgcct gctccatttt
    47401 caaggatcct accattgagc cgatcataaa gtgaaatatt taattggatc ttaggtatat
    47461 tgatacttcc gatcagccat tcctctaatt ggctggatgt tgtactttca tttctgttct
    47521 tttcattgaa aggatcagta ccaggattga atccttggtc agttaatcgt tggtttttct
    47581 cctccatttt ctttcgctgc acttcaattt cagctgcggt ccgtttttgt acttgttcga
    47641 tacgtttttg atcaataaaa ctatttaaag aatccacata aaatggatat aaagcgatca
    47701 gtaaccctac gacgatacat attaataaaa acaaacgaaa caaaagtcga cgagactgtt
    47761 tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt tttttgttct ttcttttatt
    47821 atatgggttc aggaaaaaaa tagaaaatga aagccgatga ggttgtgaaa aagctgtcct
    47881 gcatcaagta ataagtacag cccaaaaaaa tagctactca tattttttgt tgggttgggc
    47941 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaaactgcgt
    48001 tatgctttga gtaataagag cgctagtcag aaaatagctt ctcatatttt ctaggctagt
    48061 gagcttatta ccgagaagca gctgattgaa caccgtttac cgagaggtca tgaaaaagct
    48121 actttgtttc gagtattaag aaaaattctg tttcaaaaca aggagatgca acaaaactta
    48181 tgtcgcatcc tctctcctta gaactttcac ttatgttttt cttgtaaaat tcataaatat
    48241 tttcatgaat tttctaattt cttgcctacc tctcgcatag gatatatgat gaatttatct
    48301 aaagtttgca aaggagttcg acaattgaaa aaatatggcc catttttagc aatttttttc
    48361 attgctttgg catttctcat gcctcattta ttcacacata aactaatttt gggtgctgat
    48421 gccccattcc attacaatcg gttctatgat gccgcgcaac aaattaaata tggggatttc
    48481 cattattttc cttcccttta tggattccag caaagtggca ggatcgtgaa tgccgtttac
    48541 ggcccatttt tcgcttattt acaaggattg atcgtgttgc ttgcaggtag ctggtttcat
    48601 tatcagattc tttcaaattt cattctttat cttatttcag gattttctat gctgatttta
    48661 ctgagatatg tcaatgttcg aaattgggta agtgtaccag tagccgtttt attcatgagt
    48721 acgtattcta ttcaatactg gtctatcaac caaggattca ctagctgggg gacttgtttt
    48781 tatcctttat gtatgatccc tattgctgat ttcgtccttc ataaaaagtt ccctgttatc
    48841 aaagtcgctg tctcagtggg acttatgaca cagatccatt tactgtcttc gatcatgtta
    48901 gctttgatgt atatcccttt ttatctttat tactttttta accagactga aaaaggaaaa
    48961 gcactgcttc aactgattaa gtcggtcttg ctttattttg ttctgacagc aaatatttgg
    49021 gcaggattag ctattgttta cagtgggaat aagattcttc ctccctttgt taacagagaa
    49081 atgagtcaaa aggcgataga tctggatggc agttattggc tccattaccc taaggccttt
    49141 cctatattga tattatcagg ttttttgctt tttattttct ttcaacaaaa gaacacctta
    49201 ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt ttctttctac tagcttgatt
    49261 ccatggacga cattgatcga aaaaaatgtg ccttttatta gtttgatcca gtttccattt
    49321 cgatttttcg tgccatttac gctattgctt ctactttacc ttgccctttc actgaaccag
    49381 tggtctgaac aaaagtggtt ccgtctttta agtatatttg gcattcttat tttttcagca
    49441 cagacgatcc agaacttata ccagcatctg gaaaagtggg aaaatgaaac atttgtcagt
    49501 cgacatactt atctattcga tacgccggaa gaagcaagga aaacattctt cagcaaagat
    49561 atgtctacca gcttgttcgt tttccaaaaa accacacctg actatctgcc aatctataag
    49621 gagacaaaag acaataaata cgaccggtat aacgaagaaa tactagaaaa cgaaacaact
    49681 tttataaaaa cacatccagg cggtcttttg acaatcaagt ggaaaaacac tggggacaaa
    49741 actgttcata tccctgttat cgtctacgat cggactgtgc tacagcaaaa tggaaaaaca
    49801 ttgactgatt atgaagtaac agatatcggg accccaatcg tgaagcagca aaaaggaatc
    49861 aacgagctca cgcttcatta tcaaacgcca atctatttct atttcattct ttctcttact
    49921 ttgattggct ggtttacctt gctatgttta tttatttatc atagatacaa gcttttacat
    49981 gcttaggcaa aagggataaa tacatccgat caaaaaactc tccaaacggt ataatcgttt
    50041 ggagagtttt attttaatca gtttttttat gttatatgtt atatttttta ttcgttcaca
    50101 tctaattcga tttccacccc gtagtgatca ctgatgattg gactatcgat cccatcaaaa
    50161 atccgttgat attttttaac ctgcattcct tcagggacga aaataaaatc tatacgcaat
    50221 ttttctgtat tttgttccca accatctatt ttcttttcca cagtagctgc ttttcctttt
    50281 tcattcgcga caacatacga atcttgaaga agaaggcaac tttctcttac agtataataa
    50341 ccttgagagt ctactggatt attgaaatca cctaggaaaa aaagtggtac gcgagtttcc
    50401 aaaaagtagt tttccaagtt tttccactca aaataaaagc cacttttttt atctgtccac
    50461 caagaaaagt ggcagctcga gacaaaaatg tcctgatcat ctatctttgt tttcccaatc
    50521 aagatcttgc gtgtctgata atcttctttc ttttgaaatt gggagacggt aaggacctga
    50581 ctttccaatg tttttttcgt aagcagtgca tttccttctt catatttatc ataaccgatg
    50641 tggctcattt cccaactcca aaaatactct tttccgtgtt cctttaaaag ctgaactaaa
    50701 cggtaggcaa aattatcttt acggataggt acttgattct ttaccggaca gaacttcatt
    50761 agcttcgcag gttctacttc ttcagattcc agtaattggt tgatttcttg taaagcaatc
    50821 acttcataat cttctaacag gatcttatct gctaattctt gcaatttttt ctctggttct
    50881 ggctcaagcc agctatgcgt gttgagtgtc atgaatttca ttggttttct ccttgtcttc
    50941 atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa cctctccagc aaatagtgtt
    51001 ctcctgctaa ctcctcagta ataagctcaa tggaccagga gctatttttt gtttggctgt
    51061 ttttatcact tggtgcaggg cagctttttc acgacctctc cactaaacag tattcaaact
    51121 gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg aggagctatt tttgtttggc
    51181 tgttcttatg acttgatgca ggacagcttt ttcacaacct ctccttacat tttaatggag
    51241 ccgatcactt taccagctgt cactgtacct aattgcttga tcactacttc ttctacttta
    51301 tcgtttgtaa atacgatcat gatcgttgga tctttttctt cgttttggat cacatcaaga
    51361 tccatctcag ctaatttcgt tcctgttcct acttcttggc cttctttgac agcaatctca
    51421 aaagctggct gattcatttg gactgtatcg attcccatat ggatcaaaac ttcgatacca
    51481 tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa tacttgtcac ttttccagcg
    51541 atcggcgcaa caacttctct tgatgttgga ataacagcaa agccgtcacc catcattttt
    51601 tgtgagaata ccggatcttt tacttcagat aaaggaatca cttctccaga agctgcggaa
    51661 actagttctt gttctatacc taagtattgc ttactacctg cttgtccatt tcctgtagaa
    51721 accatttctg gctctggaat ctctgctcct gattgcagca gatcttcgat atctgatttc
    51781 aagacatctg cttttggtcc ataaactgct tggactccat tgtctttgac gatcaatccc
    51841 atcgcccctg ctcgtttcca ggcttcttca gtccctactt tttctcgatc atttacactt
    51901 acgcgtaacc gagtcataca agcatcgaca tctttgatat tttcttttcc tcccagcaaa
    51961 tgaatgatct ggaccacttg ctgatctgct gttcctgttc cgctgttaga tacaacggtt
    52021 tcttcactgt cattgtcgta atttccgtta cgtcccggtg tagcaaagtt gaattttttg
    52081 atcaagaaat ttgctaagaa atacgtaaca acaccaaaag cgatcacaca caacacgaag
    52141 ttgataagat ctccacctag acccgctttg atagctaacg gtgtccgagt cagcaattcg
    52201 atattcccaa atgaatggac ccgcaatggc aagatatctg ccatcgcaaa tgcagcccct
    52261 tggatcactg aataaatgac atataatggc acagcagcaa acataaacat gaactccaat
    52321 ggttctgtta cacctgttag aaagacagcc aacgctgctg aaaaatacat tgatttatat
    52381 cttgctttct tatcaggatc gacattacga tacatcgcaa aagccattcc catcaagata
    52441 cctgaagaac caatcatttg tcctactttg aaacgagccg gcgtccagtt atgcaacaca
    52501 aactcatatt gcgacatatc ccctgcacct ttaagattca ctaaatcagt ggcccaagcc
    52561 aaccataacg gatcttgccc aaatacttgt gtccccgcct gtgcgcctga taaaatctca
    52621 tacgatccgc caagctgtgt atagttgata ggaatcgtca gcatatgatg caatccaaat
    52681 ggcaatagta aacgttctaa tgttccaaat aaaaacggtg ctagaatcgg tgcgctttct
    52741 tgtgattctg caatccataa accaaaatta ttgattccag cctgtacgtt tggccacacc
    52801 acagcaagaa tcaatgccac gattgttgac cataagataa caacaaacgg aacaaagcgc
    52861 tttccattga aaaatgacaa agcatccggc aattttctat aattatagta cttattataa
    52921 gccattgccc cgacaaatcc agcgatgatc cctacgaata ctcccatatt caaagctggt
    52981 gcttccaata cacttgtaaa aaatccttta accatgatct tcgtaccgaa cagagtgtgg
    53041 gtaaatgcat cttcattcgc aagcatgtca cttgtgacac caaagatagc cccagtgatc
    53101 cgattgatta aaataaatga gatcccagct gcaaatgctc cgcctgctct ttcttttgcc
    53161 caacttcctc ctattgctaa agcaaataaa atatgaagat taccaataat tgcccaacca
    53221 atattttcaa ttactccgcc cgttgtgaca agcggcgtcc aatcaggatt gatcaaggga
    53281 attgatttcc ctatactgat catcaaccca gctgccggca taactgctac cacaaccatt
    53341 aaagcctttc caaatttttg ccaaaactca aaactaaata tctttttcat tccgtttagc
    53401 tcctttacgc aatcggtttc gttaaacgta ttatagcgtg cgttttcttt tttgtaaatg
    53461 ctttattttt tatttttctg tctataccat tctataaaac ctataatacg tgtgttccct
    53521 tctataattt tctcctaaaa atttattttt ttaagctttt ttctatgaaa tattttcttt
    53581 tgtctattga cttgtgcaat cggttgcgtt tattatgaac gtataaaaca gctcattagg
    53641 aggagaaaaa tgaaacagat caaacgacta tttgctattg atccatggaa aatcagcacg
    53701 acacaattag ataaaaaaaa tcttcgactg caagaatctt taacaagtat tggaaacggt
    53761 tatatgggga tgcgcgggaa ctttgaagaa acttactcag gggaccacca tcaaggtact
    53821 tatttggcgg gtgtctggta tcccgataag acacgtgtcg gctggtggaa aaatggttat
    53881 ccagaatact ttggaaaagt gatcaacgcc ttgaacttta tcgcgataga tatttcgatc
    53941 aacgatcagc tgatcgactt ggcttctttg gaaccagaag acttttactg ggaattagat
    54001 atgaaaaatg gtgtattatc tcgtacattc acaatcacta cttctactaa taaagtacgc
    54061 atttccttcg aacgttttct gagcattgtc aaaaaagaat cagcttatat ctatttaact
    54121 atagaaatgc ttgaaggtag cggaacagtc aaactcgtat caaaattgga tggaaatgtt
    54181 caaaacgaag acagcaacta tgatgaacat ttttggaatg agattgatcg tggaactata
    54241 gaagaaatcg gctatttgac gactaaaact attccaaaca actttgggat tgaacaattt
    54301 actgttactg cagcaatgcg ccatttcgtt aatggaaaat cagtcatccc tgactatcac
    54361 gaagatactt tagcattaca tggttgcttg tctgcagaat tatctcaagg tgagacatgg
    54421 tcagtggaaa aagaaattat cgttcttact agtagagata ttccagaagc gcagcaagca
    54481 gaaaaagctg tctcagaatt aacgaaccag acaaacaatt atatccaagc aaaagaagag
    54541 caaacagcgg cttgggcaga acgatggaag cttgccgatg tggtcatcga aggagacgaa
    54601 gaagcacaac aaggtattcg attcaatttg ttccaactat tctctactta ctacggcgaa
    54661 gatgaacgat tgaatatcgg ccccaaagga ttcacaggag aaaaatacgg cggagccact
    54721 tactgggata cagaagcgta tgctgtccct ctttatcttg ctttagccaa acctgaagta
    54781 actaagaatc tgctgaaata tcggcataat caactgccgc aagcaatcca caacgctcag
    54841 caacaaggat taaaaggcgc gctttatcct atggtcacct tcactggtgt cgaatgccat
    54901 aacgagtggg aaatcacatt cgaggagatt caccgaaatg gcgcgattgc ctatgcaatc
    54961 tacaattata cgaattacac cggcgatacg gaatatttga aaaatgaagg actggaagtt
    55021 ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt tttcaaaacg agcaaataaa
    55081 tacatgatcc acggtgtgac cggcccaaac gaatatgaga acaatatcaa taacaattgg
    55141 tatacaaata cgatcgcagc ttgggtcttg cgttacacgc gagaaaatta tttaacttat
    55201 caaaaagaag ctgctatcac tatcagcgaa gaagaactag ccaaatggaa agatatcgca
    55261 gagaacatgt acttcccagt tgacgaagaa ttaggaatct ttgtccagca tgacacattc
    55321 ttagataaag atctcatgcc tgtatccgat attcccacaa gcgatcttcc tctgaatcag
    55381 cattggtctt gggacaaaat ccttagatct tgcttcatca agcaggcaga tgtactacag
    55441 gggatttatt tcttcaatga tacttttaca aaagaagaaa agcaaaaaaa ctttgatttc
    55501 tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa gtatccattc gattttagca
    55561 gcagaattag gaatggaaag caaagctgta gaaatgtacc agcgaacagc tcgcttggat
    55621 ttggataatt acaataacga cacagaagac ggcttgcaca tcacttccat gactggtagc
    55681 tggttgtcga ttgtccaagg atttgctcaa atgaaaactg cccatgatca gttgagattc
    55741 gcaccatttc tgccaaaaac ttggaaagct tattctttcc atatcaatta tcgcggacgt
    55801 ttattgttca tctcagtcac agatgaacaa gttactttcg agttattaga aggttctcct
    55861 ctagaaattt acgtctatga acagtcttat tctttagcgg atcgtctaga aataacgcta
    55921 agaaaggagg aagcaaatgt ttaaaggggt attgtttgat ttagacggtg tcattaccga
    55981 tactgctgaa ttccattatc gtgcttggcg aaagcttggt caggaaatcg gcattacgat
    56041 cgaccacaca ttcaacgaac agctaaaagg cgtcagccga gaagactcac tctctttgct
    56101 tttagcttat ggcggaaaag aacactcttt ttcaaaggaa gaatttgcag aattagcgaa
    56161 aagaaaaaac gattattatt tagagatgat ccagacgatc gaaccaaaag atgtcttccc
    56221 cggggtcgtg cctttactgg attctttaaa agaagaaaaa atcaagattg ctcttgcttc
    56281 tgcaagtaaa aacgggccat tcctacttga aaaaatgggt cttacacctt actttgatgc
    56341 tattgccgac ccggcagaag caacaaacgg aaaacctgcg ccagatatct tcctccttgc
    56401 agcaaaagct gtcggactaa aagcagaaga atgtatcggg atcgaagacg cgcaagccgg
    56461 tatccaagcc atcctctcaa gtggcgctca accaattggc gtgggacgtg ctgaagacct
    56521 tggagaggag atcccgcttg tccctgatac gacttttctt acgatcgatt acttgaaaga
    56581 aaagtggcat gaccatggat aatccagaga tctccgtcgt accagttcca gagactgaaa
    56641 taaagaaaat cacattgaag aacgactact tagaagtcgt tcttctcaat tacggtgccc
    56701 gcctgcacca aatcttcgca ccagacaaag aaggaaaatc agaaaatgtt ttattgtctt
    56761 acgatcgttt cgaagatgtt ctaacagaca aaagcttttt tggagcaact gtcggacctg
    56821 tagccggaag gatccgggat gcttcttggg gtgagcatag attggagaaa aactgcggat
    56881 cacaccatat ccacggtggc acgaaaggct ggtctttcca attttgggaa gtagaagttt
    56941 tcaaaactcc atcatcaata ggtgtggtct tttacttaaa agatgaattt tctacctatc
    57001 caggaccaat cactgctacg atcacttacc gtttaacaaa aaacgaatta gagatgacaa
    57061 cctctgctag tagccttgtt gaaaccatct gcaatccgac caaccatgcc tacttcaacc
    57121 tttcaggaaa tggaacaaga gacatctatg aacatcagtt aacggtcttt ttagatggtg
    57181 tgcttgaatt agatcaagaa aaactgccta ctggaaattg gacaaaaaaa gaaaaactgc
    57241 caatcgactt tagaaaatcc ccaacactgc aagagatcct tgcatgttat ccagatggac
    57301 tagatgatgt atttcttttg catcatccta ggctttccaa aacttcctta caattattcg
    57361 agaagcattc tggtcgccaa atgactatag caacttctaa taaaagtatg gtattatttt
    57421 ctacgactgg attcgaagct gatttctctg tcaatggaaa acagatgcat tcaaactacg
    57481 gattagcaat cgaaccgcaa gaaatccctg atatcgttca tttccccaaa tttggatcga
    57541 tcaacctcca tcctggtcaa gaacggatca gtcagacgat ttatcggttc tctgcacaat
    57601 aacaagagaa aggtgttttt atcatggcta ttaccgtaaa agatgtggcg aaaaaagccg
    57661 gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca tcctagtatt tccgagacaa
    57721 caaagaagaa agtccgaaaa attatggatg aactaggtta tgttcctaac atgactgccc
    57781 gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat cttaccccct cttgattcaa
    57841 aagagcggat cggtaaccca ttttatcttg agatcatgga agcaatcaac gaagaagcgc
    57901 ggaattatga tatgactaca gcaatcgcta ctgctaaaaa ttttgaattg ctgttagaga
    57961 acgtccagcg tatgcattta caaaaacaag tagatggttt tattctagtg tattcagata
    58021 gtcaagatac tgtcattgat tatttatacc aaaaccacat ccctttcact ttgatcggac
    58081 agccttatca tcatgagaac gaaatcgttt atgtagataa tgataaccag cttctaggta
    58141 aacaagcaac agaatttttg atccagaatg gacataagaa tatcctgttt gtgacaaaca
    58201 cgactcatga aagtttgtat ttcgaacgat atttcggtta tcaaaaagca atgatgatgg
    58261 ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc ggaggattat ctgtcctttg
    58321 agaaaacgtt gaaagaaaac gaagccacag cattggtggt cattgacgat atcttcgccc
    58381 ttcgcacgat gcagttggcg caaatgtatg gctatgtcat tccagagaca ctctccgtca
    58441 ttagcttcaa caactcgatc ttctcaacat taacacaccc ttaccttaca agtatcgata
    58501 tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct gcgcgaattg atccatgaag
    58561 aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt gatcaaaaga gagacagtcg
    58621 ttcctttaga aaacccatac taaatagctg actcactaaa tacgctgacc atttatccta
    58681 tggtcagctt tttatgtaaa agaagatact acttctaaca cattgtttat ctgtaaaaaa
    58741 gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
    58801 gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttaa aaagcaattt
    58861 tcttgagttt cttcttattt cttggagtta aacgcttctg tcccagcctc ttttttcctt
    58921 ccttcaattt tttacacgtc gacgattcaa taaaaaaccg cctaatattg taaagacagg
    58981 tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac gcgctaactt tcatcgttcc
    59041 cataatgaat gtgccgctga ctccccacgg tacgagagaa ttgacggtcg cacctgaatc
    59101 cgctagtgtt cgtgtcaaat aggtttttga taagccaacg tcatcaaaag aacgcttgaa
    59161 tgtttctcct ggaagaatga tggacagata ctgttctcca acgatcagat tgattccgat
    59221 acagctcaag gcagtaaacc cgactaaacg agaaggtcgg tccatctttt cttttaattc
    59281 ttgaacgatg gtatcaacga tcagatattt gatcagtaac ccacctaatg ccaatgcaag
    59341 taaaatcaaa ctagcagaac ctaacatact catgatcccg cctcgagaaa gcagttcatc
    59401 tagctttgga tcaggtgtat ttgcgacata accattcatc aagatgtctg ctgcttttcc
    59461 gaccgtcaaa cttttctcat ggataaaaga aagaacgaga gcagctgtcg atcccgctag
    59521 taatgtaggg atagccggaa tttttttgat tgccccccca aataaaataa ctagtggaat
    59581 caatgtccaa ggagagatcc aaaagctcgc tttcatgttt tggatcattt cattgatact
    59641 agctagatcg gctgaatgac tgttatgtcc taatatcgta taaaaaatca acgaaaggac
    59701 gaatgctggg aaatccgtat aacgcatacc agcgatatgt tcgaatagat taactcctcc
    59761 aatacccgct gccaagttgg tcgtatctga taaaggcgag cagttattcc ctaaaaaggc
    59821 accggaaacg actgcgcctg tagtcattgc atcattgaat ccaagtaaat gaccgatccc
    59881 caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa ctgccgacag tcactccgac
    59941 aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc acagaaacaa gtttaaatcc
    60001 ataaaccata atcgtaggga tggttccaga taaaatccat gaagcaacta agacaccaat
    60061 caaaagaaaa atcaggattg gaatgatccc tggagtgatt cctttgatga tcccgtcatg
    60121 gatctcatcc catgtgaact ttttaaatct gccataaaac aacaaacaca tgaaagctgc
    60181 aaggatcggg atatgtggcg agagctggaa tccgatgatc agtactccta ggagtgccaa
    60241 caacacgatc aatacagcga tactttcttt taaagaaata tttttattca tcgtcgatct
    60301 cctatttcaa atgaaaaggc cctgccatga aaaaactatt cacttggcag gacctcctac
    60361 taaatcagcg acaaaacgtc ggctgaaaga cttatttttt tatttttctt ctaaactttt
    60421 ttctacctca atcccccaag aatctttctt gaagtgattg atgatcaatg gaataacgaa
    60481 catgaccact gtgatagctg ctactaataa tgcatcactc aatgtcgctg tacctaatgt
    60541 agcaaatacg acaacgatga tagagaagat cagcatgcag ctgactaccc aagctaatcc
    60601 gtttccgttt ttaccaattc ggtaaggacg ttcgaattct ggatgtttct tacgcatttt
    60661 aagcaatgaa acagcaatca aaatgtacac gatacaataa ataacagttg tagcatttgt
    60721 aagtgtcaag aatacagcac ttacgtcatc cattacacca taaagcaaag caaataatga
    60781 aataacgatt gattgtgtta gaacgacatt tctagatacg ccgtatttgt tttctttatg
    60841 gaatccgaat tttggtggaa ggaatccttc acgagctact tggatgattg tttttgatgg
    60901 tccagtaacc caagctgata attgtaaaag cacaccaata aataccatga agctgaagat
    60961 atttccgatc acttctggta agcctaggat ttgacagtca atcaagatag gctgcgtgat
    61021 atttgctaat tccatttttc catctggtac gacatttgct acaagcatcg cattgatgac
    61081 attcaataaa actaatccga tcaaagcgat aaatacgcct tttgtataat tttttgttgc
    61141 gtctttcaaa cgaggcatgt aaacagaact catttcgatc ccaacaaaaa taaatgtgat
    61201 accagctaag tatttcaatg aatcaatatg ttccaagtca gggaaagctt ttgaccatga
    61261 aaagtcacct agatagccgt ttgagactag tccgactttg aaggctgcca aaacacctaa
    61321 aacgaacatg atgactactg ggatatatac ccctagccat acaccgatgt tcccgccgac
    61381 ttttgccata tcgaatttca agttcaagat cgtgatgatc cagtagataa ctaaaataca
    61441 acctaaaacg aaccagtgat tattgccaag ttctacatta ccaaatgtgt ttcctaacaa
    61501 tggtcctaaa gtagaagcga ccattaccat acctgggaac atttgcaccc ataatagcca
    61561 tgcaacgaca aatccccatt tgctgcccag tgctgttttt acccataact gaggaccgcc
    61621 ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt gatatcggac cggcaaaaaa
    61681 caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg actgcggcta acgtaggaat
    61741 actccgaacc gttgcacaca gtgccattgt cagaccgata aaggtcccaa gacccatttt
    61801 acttacttca gatttactca ccgttgacac tctccttgat tttttggata aaataacggt
    61861 gtctttgaag tagtttcagc aataaacgaa acaattcagc gaatatttga ggggattctt
    61921 tgagtttatt gcttgaaggg tttcttcaaa gacaacctca aaacaaaggg atcgaagagc
    61981 ttaggtctcc ccttgctctt cagatccaaa catgcgtcag aaacagttag tattcaagct
    62041 gttttctaac atgattacct tgcttatttt gcttcgcttg ccaataattg gtctgcgtag
    62101 attttttcca atttttcttg aagagctgct ttgatttttt cagcatattc ttcaaagtgt
    62161 tcttctttgt tcatgtatgg tgtcattacg ctggcacgca atacagttac ttttccggca
    62221 cggttccatt cttcatctga gaatcctagt tggttcacaa attgtaatgg gctgttgcca
    62281 tagtctggga tagcaaagtc agtatgtgaa gttaagaact cattaccgta aatgcttcct
    62341 ttcacgtatg aagaataatc atatacgtca tggttcaatt tattcattgc aactaagtca
    62401 tcgttgcctt tttctttgaa tacatagtct accatattga aatctggata agttaatgga
    62461 tgaacttcga tttctttgtc tcctacttta aatgacaagt cattcaagaa gttgtagaaa
    62521 cgatgtgcac cttcgattga tgcacccatt aatttaccat atcctgtgac attcaaaggt
    62581 aagacatggt gtgctgccca aacgctggct gctgttgccc ctgcttttga accttccaag
    62641 atataagccc caagtaatgc tgggatatct gcgccttttt caaatacata tgtcgcaaag
    62701 taagagataa cgtctctcat gcggatatct ttgatgacga taccaccggc agaatatgga
    62761 acatagccca ttttatgtgg gtcaatcgtt acagattctg cttcttcgat tgctttatat
    62821 gcactgtgta cttcttctaa gatataatct ttgttttctg taaagacatt gtatttgtaa
    62881 tgaacatctt ttaaatcttc aaatggaatg aagttgttgt cttcgtctaa gaaaatcgca
    62941 cggccgtatc cgccataagc agcatctacg tgtaagtaga agtaaatacc gtctttttct
    63001 aatacgcgac gcaatgcaac gattttatcg ataccgtcga ttgctccttc ttctgttgat
    63061 cctacaacac cgactacacc taggattggt gttttttcag ctgctagacc acgaacgatt
    63121 ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa ctggcactgg aatcacttgg
    63181 tctaaaccga taccgatgat gtcggcagct tttagccatg aatagtgttt agtttgtgga
    63241 accaaccatt ttcctaattt ttctaaatgt tttccgctac gtgctgagtg agctttgatt
    63301 tcgtcgattt tttctgggac gctgtctaac agattcatga tttcttctgt tgacaagttc
    63361 attaattccc aatcgctttt tccagcaact agttcaggtg tcacttcttt cattgcaagc
    63421 ggcaatgatt tgatgttgcg ggcataccaa agtccttcta agtttgctaa agaaccatca
    63481 gcaacgatgt ggccccagcc atctttatag ctcattaatt ttgcaaattc cattcctact
    63541 tcttcttcca tttggcttgt tgcaggagaa gattcatagg caacgttatt accattccat
    63601 agcatagcaa aattgtacgc tagtaaagat ggcatcaatg tttcagagtt catatgaccc
    63661 cagtaacgtc cggcattatg ccaaggaacg gaatgggtac gcatccgcgc tgaaatttct
    63721 gatagaacat cctttgtttt attcacagtg tgttcaaaac tagcactgct tttttcttct
    63781 ggcgtaataa taggcatgtc ttgaggcatg tagttttgac gccagcctaa atgttcatcc
    63841 accaattcat tcaacaaagc tttatagatt tggccgttct cagctttgtc cccaatgaat
    63901 agggcattta ggtttagatc tttcgacaat gattcactca tagtgaaacc ctcctaaaaa
    63961 aatatttaaa ttttgtcgag ccctacatta cacctgttct tctattctgt aaactaagtt
    64021 ttggcctgat ttttaatcat attttaatat gtatcaatta tccgaattgt tcacactttt
    64081 gaaataatta aaaaaaacga gggaatttac aaatgtaaac tccctcgcaa agattgtatt
    64141 aacgacaacc agcgttctat tttaggatgg gtttcaaaat tggaatgttg taatagtatt
    64201 tccctttttc aaggtaaaaa cttactaaat tctaatcaat tactttggcc aaaaagtaat
    64261 ttttcttacc ttttcgaata accacaaact taccatcgaa ttcatcggat ggatttatga
    64321 caaaatttaa atcggtaacg cggtcaccgt taatacttat agctccgttt gaaacatctt
    64381 cacgtgcttg acgtttagat ggttcaattt ttgtggaaac aagcagttcc acgatatttt
    64441 caggtgtgct tgaaatttca acgttcggca ttttaccgaa tccttgcgcg atttcttccg
    64501 catttagttc tttaatattt ccagagaaca atgcttgcgt tattttttgc gcttctttca
    64561 agtcttcttc actatgcaca aatcttgtaa cttcttctgc caaacggcgt tgtgcttcac
    64621 gtttctcagg ttctgtctct acttttttcg ctaagtcttc gatttcttct tgagacaaga
    64681 aagtaaagaa tttcaagtat ttcactacat cgcgatcatc ttgattcaac cagaattggt
    64741 agaactcaaa tggtgaagtt ttcttcggat caagccaaac ggcaccgcct gcagtttttc
    64801 cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt taaaccgaac gcttctgctt
    64861 ctggtccttc taattttcgg attaggtcta atccagctgt gatatttccc cattggtctg
    64921 ctccaccgat ttgcaattgc acatcgtatg ttttatgcag atgcaaaaag tcgatagatt
    64981 gcaggatttg gtaagtaaac tctgtaaatg agattcctac ttccaaacgg ctggcaacga
    65041 tatcttttgc taacatcgtg ttgatgttga agtttttacc gtagtctctc aaaaattcaa
    65101 gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa tgtgatattt gcatctttac
    65161 caaacaattt tctcatttga ttggaaagtg cgtccacgtt atgttgcact tgttccatcg
    65221 tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc gatcgttcct gttccgccgc
    65281 caatcagaat atatggatga tggcctgcca attggaatct tttcatcatc ataaatggaa
    65341 tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac gccgcaataa agtgaaatgc
    65401 tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt ttgctgatta atggcgtcgc
    65461 gccaagttaa ttcatcaata atattcattt tactgacctc cgtgtagttt ttttatgaaa
    65521 gcaggaacct gctagcatgt gtaattaatt atttcttcag gataggatag gaaataaaaa
    65581 aagtcccttg gcatataagc caagggacga aatctcgcgg taccacccaa tttgtatgtc
    65641 tagatatcca acatacctct cgaacattta acgctgtcgc gtggcaatca ctgccaaaga
    65701 ctcctgaaat gtaattcgct ttaaagcatg tactggtttg cagcgaccac cagctttctg
    65761 aaacattggc tttaacaact acttcgtttc gatcttcgtc ttgttattat taatatgtgt
    65821 ctatcataga gcgcaacttt ttctttgtca acagaaaaag gatatttttt ttaaattcct
    65881 cattttttct tttttgaatc cgctctaatt ccgaacattt tattttcaat tattgttaaa
    65941 agaaataact ttttctgtat tttttctgca atttatcgag aagtcacttt actttgcctc
    66001 ttattctttc ttcgttacaa taaggaatgg gacaagtaaa aaaatgaaaa agcaagggac
    66061 gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc acttctgctt taactatcgt
    66121 tattttaatt ctaagtttgt tttttgtcat ccgatcatct acaaaaaaag aaccaatcat
    66181 tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca gatgataagc aacaactagt
    66241 tactcaagca aaaaatctgg ctcaaagcta cgattatgac caagcgattg cgttattgga
    66301 aaaagatagt aagaacggat ctactgaaac acaacagctt cttcaaacac taaaaaagga
    66361 gaaagaacaa ctgatcgact ggtctgatcc tactcagatc tctcatgtct ttttccacag
    66421 cttgatcgtg gacccgcaaa aagccttcca ctctcaacag gcacaaggat acaaagatta
    66481 tatggtgact gttgaagaat tcaaccgttc gatcgaacaa ctttatcaaa atgattttgt
    66541 tttagttaat ttgaatgatt tgatccaaaa agacgaacaa ggaaatcttt cctttaacgg
    66601 gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca caagatgatg tcagctatta
    66661 tgaatatatg gataattccg gttttcctag ccgattggtc gtatcaaata acaatgaaat
    66721 caaaaatgtc tataaagaga aagataaaga agaaatcggt gactttgaca tggttcctct
    66781 gatcgatgcc tttgtcaaga aacatcctga tttttcttat cgaggcgcaa aaggtacctt
    66841 ggccctgaca ggttacaacg gagttttagg ttatcgaaca tcaaaatctc aatatggaga
    66901 caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa gtggcggaac agttgaagaa
    66961 agacggctgg agctttgctt cccatacatg gggtcacttg aatatgactc aagcttcact
    67021 agaagatgta aaaaaagaca atgaattgtg gcagcaagaa gttgcaccta tcctaggaaa
    67081 aacaaatatt ctgatttatc catttggtgc agacatcagc gactggcagc cttattcagc
    67141 agaaaatcaa aaatttgctt acttgaagag tcaaggtttc gatattttct gtaatgtcga
    67201 tgcttctaca ccagcttggg gacaattagg tacggatttc tatcgaaatg ctcggatcaa
    67261 tatcgatggc attcgttttc aatctgattt agacggaaaa aatcctattc ttgatccatt
    67321 catcaatgtc catgatgtct atgacaaaga agcacgcgaa tctgcttgat tttacgtcat
    67381 ttatgaacca aaaaagccga actgacattt tatcgtcagt ttcggctttt ttatgcttta
    67441 tttcttcttc ggtgcgattc ccttgatcag gacttctgtc cattctgctg tatatggaag
    67501 cagttttgcg tatatctccg gcttagaaat tccttctacc attgcttgaa aatagaggat
    67561 caagaactca tccgaatatt tcaaatccac ttttccttct ttccgccctc gatggaaaag
    67621 atcaagcatg atactgaaac tttcttgcgt atacgcatcc atcgcgtcag aaaattcttt
    67681 tttttctttt tttgtatagt atgtcatcaa atcgatataa aattgtttgt tcactcgatt
    67741 gagataacgg attttgtttt cactcatggc aatcagtgtt tcttcaaatg gaagattttc
    67801 cgcaatcaac gctttcgctt cttgccctaa atcattcata aatgcaaaaa atacttcata
    67861 aatcagccct tccttgctgc caaaatattt aaaaatcgtc gctttactta cctgagcgtt
    67921 ctcagctacc ttatccattg tcactccagc ggttcctatg tctgtgttca tcaagtcaaa
    67981 agctgcttgt aaaatctctt tctttttctc ttgtgctctc ttttcaaaac cgttcatttg
    68041 tagagcctcc cgtaatttta aacttttata atatatatag ttcaaattta ttctgaggtt
    68101 tattataact atctattgag aaagtatcaa gctagcaatt ccttgtttat gaattcattg
    68161 acagaaattt ataaaaagaa tattatgtac taaaataata aaaaaaagtt ttataaaaag
    68221 gtataaaacc tttttattaa actatttaat cttgtttagt atatattttt agaaaaagga
    68281 gtggggtttt tatggcagaa atcgtcaaag tcacacattt gaaaaagagc tttggtcgtt
    68341 tcgaagcttt aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt ggatttatcg
    68401 gaccaaatgg ttctggaaaa tccacgacga ttcggacact tttagggatt ataaaaaaag
    68461 acggcggaac ggcaacgatt tttgggcaag atgtatggga agatagttta tctatccatg
    68521 aacgtctttc ttatgttcca ggcgatatct ctttgtgggg aaatttgact ggaggagcga
    68581 tcatcgatct cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa gatgaactga
    68641 ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa ggaaatcgcc
    68701 aaaaagtggg cttgattgct gctttggctg ttgattcgga tctctattta tttgatgagc
    68761 ctacttctgg tttagatcct ttgatggaaa cgattttcca agaagaagtt gaaaaattga
    68821 aagaacaggg caaatccatc ctactttctt ctcatattct cagtgaagtc gagcgactag
    68881 cggataaagt cgtgatcata cgcgaaggaa cactcgatga agaaggaaca ctcgatgaat
    68941 tgcgtcattt gactcgttcg accatcacta tagaaacaga agcagagaat agtcacttag
    69001 cacaattgaa cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa tttgctgctg
    69061 ataacgaagc tttcgatgtg attttagctg aagcgtccaa attaggtgtg aaaaaatttg
    69121 aatctattcc accgactctt gaggatttat tcatgagaca ttatgaagga tgaggaggaa
    69181 gcgaaatgac tgataaattt tcacgctggt ccaccctttt ttctcaaaac cttagccgtg
    69241 actggaaaaa gatcctgata tggctagtcg gtgtcactgc tttttctggt ggttttgtcc
    69301 ctgcgtttga agaattgact tccggacaag gattagctgg attatacgaa accttgcaaa
    69361 acccggcaat gattgcaatg gtcggaccaa ctccagcttc gaatgctgct gagtatactt
    69421 taggagcgat gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct gctgtgatct
    69481 ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga acttggtctg attgaactta
    69541 ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct gaaagtattc
    69601 tgatcaattt gcttttagca atatcgatca gctgtacgat gatttttttc caagcggatt
    69661 cgatcactgc aaaaggtgct tggctttttg ggctatctgt aggtagtatg gggattttgg
    69721 ggagtgccgt tgcactgttt gctgcacaac tgatgccaag ttcagccagt tcgaatggtc
    69781 tgtctttagc gtttttaggt ggactttacc ttctacgagc aataacagat gtagctgatt
    69841 cctccctttc gatgtggaat cctttaggct ggtcttattt gacctatcca tttacaacta
    69901 acaactggat tcctttgctt tatttgtttt tgttcagtct aatcttgata atcagttcat
    69961 ttgttttaga ggaacatcga gatttgaaca ccggctatat ccccgaacgt gaaggaaaac
    70021 cgtatgctaa acgttctctt ttatccttgc gtggtttatt attctatcta aataaaggga
    70081 tgacaatcag ttggcttatc acttttggtt tgatgggggc ggcatacggc tctatctacg
    70141 ggaatatgca acagttttta gaaagtaacg acttaatgaa acagatgttt atccaatctg
    70201 gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt agtcttgatt tgtctagctg
    70261 ctattttacc aattgctagc atcaatcgtt tatttacaga agaaacccac ggacgtatga
    70321 atcagctgtt cgcaacaaaa atttctagga accaacttta ttggaccaat atgttactag
    70381 ctattctatt tgctatattg gcaatcctga ttagttctgg tgcactaggg ctttctgctt
    70441 tggcttcgat gaaggatgcg aaagacatgg atctattgat gtttcttaaa gccgggttca
    70501 atttcctgcc tgccgtttta gtgtttatcg gaattagtgg ctttctattc ggatggcttc
    70561 ctcgaatcgg taaacttgct tatatctact tagcttactc ctttgcactc aattactttg
    70621 gcggaatttt ggatttacca gaatggtttt ccaaaacagc tgtccctagc tgggttccac
    70681 ggatgccaaa cgattctttt gatctttccg tgttccttac gttatcatgt atcagccttg
    70741 cactgttcgt ccttggttct attggttata ggcgaagaga cttactagaa ggataataaa
    70801 aaagcatgta caatttcatg ctagcctcca aatctgggtc aaaaatccaa catttggagg
    70861 tcattttttt atttacaagt cttctaactg ctctttatca atgatccaga cttctcgatt
    70921 ctttcttttt acataaccat tctcctctaa taatttaaat tttctagata aagtttcggg
    70981 ggtcgtaccg ataaatgcag caagttcttt cattttcatt ggcaggaaaa agtgatcctt
    71041 ccctgtcgct ttagctaagt caagcagata gacagcgact cgttcttcta ctttttccat
    71101 catcaaaaaa gttgtctgct gctgtacttt tgttaatttc tcaacgttga ttgctaaaag
    71161 tttcagacta agggcgggat aatgcagtaa gagttccgag aaatcttttt gtctcaatat
    71221 gcaaatttcc gttttttcta gtgcttcgcc aaataaagac tcatttggaa cgcctagcaa
    71281 ctggctctct ccctcatatc cgcccggctc tattactcgt aaaagctgtt cctttccgct
    71341 agcagataat tgatacactt tcatactgcc ggaggccacg atcactaatt gaggttctcc
    71401 attcggcgca agaatctgtt ctcctttttc cacatagtga tgtttgacaa gtgcgtgtac
    71461 tttttcttga tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa cacataaatg
    71521 atcatgactc ataatctctc ctccttctaa acagctattt ctaataaaga aacataactt
    71581 cccttattcc aactgataat tttcttttat catagcataa acgtcaagcg aaccagatac
    71641 cagcaaatag agtggatttc tttttgtccc ttgctttatt ttccttcttt tgagacctta
    71701 agtaattgat tcctatcaat tttttaaata tttacttttt gaataatcaa aaacaaacct
    71761 tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg ttgtctattg
    71821 aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg tttcagcggt
    71881 tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca tttgaaaggt
    71941 tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca aatagtcaga
    72001 caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat aatccttgat
    72061 atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg ctgcaatgct
    72121 accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt attgtttttg
    72181 attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc ggtacgcgct
    72241 ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag gtttgctcat
    72301 gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc atttttgcca
    72361 gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc tctctttgag
    72421 ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc caagttccat
    72481 tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata tggacaaata
    72541 gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa aaaactgcga
    72601 tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa aagcgttgaa
    72661 aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg ctctcctaga
    72721 taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc ctggtcaatg
    72781 atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca aacatctaac
    72841 atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt tccctgctcg
    72901 atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt cgctttcatc
    72961 atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt cgatatcatc
    73021 gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc ttgaaaagct
    73081 tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc gccaatcggg
    73141 gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa ttgcgtgagc
    73201 cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct tgagattttt
    73261 taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt ctccgtcaag
    73321 tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt accgactttt
    73381 cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt catgaacacg
    73441 aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc ttcttttggt
    73501 aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac tttagaaggc
    73561 tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata ctcgatctca
    73621 tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc tcgaagcgct
    73681 agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa ctcagctagg
    73741 gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt acctgcaact
    73801 ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc tacgatcaca
    73861 ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa gttcaatgca
    73921 tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc ttccttaata
    73981 gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac cgctgcactt
    74041 aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc tccaccagaa
    74101 accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga ttctacacga
    74161 tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac aatattgctt
    74221 ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat tttgtgcttc
    74281 tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg caaaagctcc
    74341 ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt ccaacatgtc
    74401 ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa aataactagc
    74461 tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc cgatctcgcc
    74521 atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct gctcaatcat
    74581 ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac tttttttcac
    74641 aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca ttaatgaaca
    74701 attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt cttgaagttt
    74761 gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac gaacagtgta
    74821 gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat tactgggatc
    74881 catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg ctcaaaaagc
    74941 tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc cgaacgtgca
    75001 aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt attaggcagc
    75061 gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag ataagtaggg
    75121 gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa gaattagatt
    75181 tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt tctttttgcg
    75241 gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat aactgacaga
    75301 agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg gctctgtcgt
    75361 ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg ccgaatgcaa
    75421 aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt caaaatcatt
    75481 agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg ctgtgatatc
    75541 cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta attgctgatt
    75601 gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt ccgcttttgc
    75661 tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt tatttttaag
    75721 atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt ttgcagcttc
    75781 taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat cgatttggtc
    75841 agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt ctcctgaatt
    75901 atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag caccagaaga
    75961 gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa aagctgtctg
    76021 tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca ttcttttttt
    76081 catcactttt cccatcctta ctacttttta actaatttct tattataagc aaaaatgttt
    76141 ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt ttattttttt
    76201 gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt gactgctgga
    76261 atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat atatagtggt
    76321 gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga agctagcaac
    76381 tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt aaaagtaata
    76441 taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc aaaaagaact
    76501 acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat gaagatgatc
    76561 gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt cagccagact
    76621 tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa cgtcacaggt
    76681 acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt taactgatga
    76741 tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc cacatcgatc
    76801 aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc accgaaaaca
    76861 gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt ttgagatttt
    76921 gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc aatatgtctt
    76981 gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc cggtaccgtg
    77041 tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat attaaacgcg
    77101 tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta ttttttcatc
    77161 agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac taatacctca
    77221 tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat cacaatttct
    77281 tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg aacatctacc
    77341 cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat aaaccataca
    77401 aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa acaagtatct
    77461 aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca ttttctttat
    77521 acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa taaaaacgga
    77581 ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca agtaattctt
    77641 gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt ttgtatagat
    77701 ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa aaaatcaata
    77761 caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg tacaaggaaa
    77821 aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa ggaagaacaa
    77881 cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag taattacctt
    77941 ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt acttttttca
    78001 tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt tcatttcttt
    78061 tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc tcatcagcaa
    78121 atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct cttaattatg
    78181 ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg tacatttgtc
    78241 tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca tgatcaaatt
    78301 ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca tatgaatttt
    78361 ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata actgccgctt
    78421 tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct tcagaggatc
    78481 gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg tcgatcttct
    78541 cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa cggtaactat
    78601 ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc ataatatcag
    78661 caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa gtaaagtgag
    78721 tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct tgtacttcat
    78781 caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa tgacgaatag
    78841 ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa gctgagccat
    78901 atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc atttcttcga
    78961 tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa gctacaatac
    79021 tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta tcttctgtca
    79081 acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga tgattcttcc
    79141 attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta ggatgagcag
    79201 gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt ccatttttag
    79261 taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt tttagattat
    79321 cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct cccgtgatac
    79381 gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa accagctgta
    79441 tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc gaaatatagt
    79501 cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc gtatctcgat
    79561 ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca cttcctgcta
    79621 cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt tgttccgatt
    79681 ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag acttctaata
    79741 atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga tctctttcca
    79801 aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga accgtataag
    79861 aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc caatcataaa
    79921 caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag gattcttttg
    79981 gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc aataaacgtt
    80041 cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga tcgatttctc
    80101 tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg tcaaaattca
    80161 atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt gccgtatcca
    80221 tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc ttcagatatg
    80281 cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt taaagtggtg
    80341 gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga gtatcatttg
    80401 ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc accatcaagg
    80461 ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct acgtaatccg
    80521 ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg gtcccgaagt
    80581 tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc ttctgctgtt
    80641 cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg ccattgtacg
    80701 gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt tactggatct
    80761 ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc gaagatcgtc
    80821 aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc ttttgcccca
    80881 acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt cagtaaaata
    80941 tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat gacttcaaaa
    81001 gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc agtcattcca
    81061 aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat tccggaaatc
    81121 gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat aagtgcatct
    81181 tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat atcaggaata
    81241 ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc gattccagcg
    81301 gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa atcagcaggg
    81361 atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc agcgacagca
    81421 tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa agctgccatt
    81481 tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac ttctaaacct
    81541 cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac gatcacggca
    81601 cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac atttctaata
    81661 gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg ttttgcacca
    81721 ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg tacgacttct
    81781 accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac atctaaacaa
    81841 aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc actgatttct
    81901 cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc tttttcaaaa
    81961 acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga cattccacct
    82021 gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc gatcaaacca
    82081 ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta attctttagc
    82141 tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt ctttgtctcc
    82201 atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat gcccgccccg
    82261 gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct tttcctttaa
    82321 ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct gcacctcatt
    82381 tacattttta taaatacctc atggggtata ttaaacagga gctttattaa tatgtcaacc
    82441 agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc gataaggggt
    82501 attatctaat tataaaaata gaggagaatg tgttatggag attgataata aaaatatcct
    82561 gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga tcgaagacga
    82621 aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta ttgatcgcgt
    82681 aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg atagtaatcc
    82741 agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa agtaaaggaa
    82801 tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca gaaacaggga
    82861 aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta tctgtaaatg
    82921 gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat ttgcaaggag
    82981 tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa agttctttac
    83041 ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg caatcccaag
    83101 gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc agcttcaaga
    83161 aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa aggttgtgaa
    83221 aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc
    83281 gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg
    83341 tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc tcctcatatt
    83401 ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta aggaagagat
    83461 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gatttctaca
    83521 tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt ttaaggaaga
    83581 ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa atagctgctc
    83641 atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc gtttaccaag
    83701 aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa acaacttctc
    83761 ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct atttatcaaa
    83821 aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat ctttcggtac
    83881 tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc aaaaatgact
    83941 ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc aacatagatg
    84001 acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt tttagatagc
    84061 ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc aaacaacagc
    84121 caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt caatttatct
    84181 gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg agcaatgacc
    84241 ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat ataaaatgac
    84301 tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat cgataaaaga
    84361 ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt atcgccctac
    84421 ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc aatgatttca
    84481 ctgtttttat ttttctttac agacactgat attatgagct aatttgagat aatcacttgc
    84541 tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt actagtactt
    84601 tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt ttataatcga
    84661 taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa cgcaccagac
    84721 gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca atcgtatctt
    84781 cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat atccgatcac
    84841 cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact gctgtcttag
    84901 gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc tctgcttgat
    84961 ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg ctttctcctg
    85021 tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa agccatagca
    85081 gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata atgggtcgtg
    85141 gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc tagtgcagcc
    85201 ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt attccttttt
    85261 atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact caacgcattt
    85321 tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc aagctctgtc
    85381 ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa accgactgtc
    85441 ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc tcgatagtct
    85501 ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg tctgccttgc
    85561 ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat ttctcggcta
    85621 aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa taaatcgatc
    85681 acttcttcgt tttctgcgat agcaccagtc aatgccgcta ggacttgata ttcttcactg
    85741 atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac agttggttca
    85801 ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat tttattttta
    85861 tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat tgcttcttgg
    85921 atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg gatttctttt
    85981 tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc gtcactgact
    86041 ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc aggaagatgt
    86101 ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa ctttgtgatc
    86161 atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg cagaatcaac
    86221 ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa tggaacatgc
    86281 tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc caagacagtt
    86341 tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt tccaattgct
    86401 cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat ttcgttgtcc
    86461 atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc ctagagataa
    86521 ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga atacaaagat
    86581 attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt ttattggcta
    86641 ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc ttctaggtct
    86701 tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt tagtatgttt
    86761 tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg atcattggac
    86821 ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct attggcaata
    86881 ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat cctgttggcc
    86941 ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg ttcgttccag
    87001 gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat gtaccaatta
    87061 attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca aacgttccta
    87121 aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc caaacaagaa
    87181 tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca agattccaac
    87241 taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga gctgggccca
    87301 tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat gcgatgacaa
    87361 tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac acaccatctc
    87421 caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc atatcactgt
    87481 tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat gcttctaaac
    87541 gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca attgcatcga
    87601 tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga tttgtacgac
    87661 gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa cgtaaccgag
    87721 ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat tcaaagatac
    87781 gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc tctaaaccgg
    87841 ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt ggatcgaagt
    87901 ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt ccgtattctt
    87961 cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg taatcggtga
    88021 ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa ctacctctgg
    88081 aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac acgtcttcta
    88141 cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca actttattga
    88201 agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca gaattaccaa
    88261 tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg atatttgctt
    88321 ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt gtgactttcg
    88381 gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc ttgttttctc
    88441 ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat gtgggttgcg
    88501 gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga cgcattttag
    88561 gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga ccactcgtat
    88621 tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca cgagctttga
    88681 cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta cttactagat
    88741 aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca tcattgttgc
    88801 ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac ggttctcttt
    88861 ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc acatttgcca
    88921 gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt gttgctcctt
    88981 cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg gcaatacttt
    89041 gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat gtcttcagat
    89101 aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct gcaaaatcct
    89161 gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc acaccggcac
    89221 cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt ttttgaatgc
    89281 tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa tgcttgggta
    89341 gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc ctccatttga
    89401 acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc tttccaataa
    89461 ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa gttttctgct
    89521 cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc attgtttgct
    89581 gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg catcgtatcg
    89641 atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat atcttctttt
    89701 gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca ataaggagca
    89761 cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga gcgtttcgct
    89821 gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag ccattgaatc
    89881 gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc atttatgccg
    89941 taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc ggtattcatg
    90001 acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa tgccatttgt
    90061 ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc gcttccataa
    90121 aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt tggtaacatc
    90181 actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg atggatattg
    90241 aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc atcggtcagt
    90301 ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc agctcgttct
    90361 tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa ataggcatcg
    90421 atcactaacc ctgttttttc gtggaaaaat tcttgatagc cttcattttt taagttatct
    90481 gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg acgtcctgta
    90541 tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc agcaatctga
    90601 tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac agaattccag
    90661 atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt gaactctttt
    90721 tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga gctagttgta
    90781 ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc cattatatgc
    90841 aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa ctgtcaaaat
    90901 tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt taatcaattc
    90961 ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta aggtgacgca
    91021 aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt gatcaccaaa
    91081 tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc cctcagttct
    91141 ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa atcgattcca
    91201 atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc atactggatc
    91261 atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg caccgctgtt
    91321 tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg ctgctgttcc
    91381 aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca ttcattgttg
    91441 atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg acgaggacga
    91501 taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg taactttttg
    91561 ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa agaaacaaaa
    91621 aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg actaagatgc
    91681 atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag taatttcttt
    91741 tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt aatcccgagc
    91801 cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac acggtccaat
    91861 cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg ctgatcttcc
    91921 gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc tccgtataat
    91981 tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc tttgatcttt
    92041 cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat ggatacttgc
    92101 tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa taaaaacaat
    92161 agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata ctcatttcgc
    92221 tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc caaatattga
    92281 tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga ggctgttccc
    92341 ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct ttctaataat
    92401 gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg gcacacggta
    92461 ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc cttcttctac
    92521 tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga gctgtgctcc
    92581 aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt gatttattgc
    92641 tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa tgctctcttc
    92701 ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga ctggacgata
    92761 ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc gtgctgtacg
    92821 gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa aagttacttg
    92881 gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt catctaccca
    92941 gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt cgggacgaga
    93001 atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct ctacaatagc
    93061 ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa gcccttgatt
    93121 tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa aaagaattga
    93181 ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt cagctatttc
    93241 gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga tcttttgctg
    93301 aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt ctgcagaaat
    93361 atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat ccaatttttt
    93421 tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt ctgtgtaaac
    93481 atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt gtttttcact
    93541 ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta acttcgattg
    93601 cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa tagccgcatg
    93661 aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc tttcttataa
    93721 ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg ctttcaacct
    93781 tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt ctaggtctgc
    93841 ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga gatgtttcaa
    93901 aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc caaataggaa
    93961 acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag aatagacaca
    94021 tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga tgagcagatt
    94081 gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa aaagctgctc
    94141 cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat ggtacttcat
    94201 tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta cgtccagcta
    94261 aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg tgacaaacag
    94321 ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga tctattgctt
    94381 ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca taatcatttg
    94441 catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa tcttcatctt
    94501 cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct aaaggtacat
    94561 atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat acatcataaa
    94621 aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg tacttttcta
    94681 catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa aattgcgtta
    94741 ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct ctttatatgc
    94801 ttcttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt tctctgccca
    94861 gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt tcaatacctg
    94921 ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct ttccttgaat
    94981 cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac gagctattcg
    95041 atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta atcgttcaag
    95101 aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg gtgagaaacg
    95161 ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa ccgttgttaa
    95221 taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat cctctcgtct
    95281 attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat gcaactcgat
    95341 tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt ggattgtttc
    95401 aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt ttgctgcaac
    95461 tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca ttcgtccacc
    95521 gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg ctagctcact
    95581 taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc cttttccgat
    95641 atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac gttgtttata
    95701 ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg tcgtcatagg
    95761 cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg attgatcaaa
    95821 ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga atcatctatc
    95881 attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt tatttttttt
    95941 gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct tcatttccca
    96001 aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc ttagcaaatt
    96061 ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact gttttgacgt
    96121 atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg gaatagagca
    96181 tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat aaaataaaac
    96241 cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta ttcaacatgc
    96301 gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca attggctttt
    96361 ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt ttgtcaaaaa
    96421 acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag ccatcttcaa
    96481 agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca gaggttgtga
    96541 aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt ccacattttt
    96601 gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata tcagaggttg
    96661 tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt
    96721 ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta ttgagaggtc
    96781 gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag cttctcatgt
    96841 tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt tattcgtaaa
    96901 gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta taggatttcg
    96961 ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa ccgtttcttt
    97021 gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt tgacatttgt
    97081 gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa taaatctact
    97141 ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc aatgcggtaa
    97201 tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc gttttcagct
    97261 atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct caaaccctta
    97321 ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat tcctccagtt
    97381 attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc actagacatg
    97441 tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc atcacctact
    97501 tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc tggataatat
    97561 cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat tgttttttga
    97621 atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat acaaccgact
    97681 tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc tataaactga
    97741 tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc aattactcct
    97801 acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat ccaatatttt
    97861 actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa ctgaataagc
    97921 tttcgattag gccatccacc atattctgta accaaatata acggcatttc ataatgggaa
    97981 agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg atcataaaaa
    98041 aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct tgtccatgcg
    98101 atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc ttctttaaag
    98161 tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt gggatcctgc
    98221 gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt ttctttaggt
    98281 aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc tacatcccat
    98341 gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc tggaaatttt
    98401 ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc ttatgactag
    98461 taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc ggatcatatc
    98521 cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta cgtacttttt
    98581 ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta tcaataccga
    98641 tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt ttcgttggaa
    98701 aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt ggaatgatcg
    98761 caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca gataaatcaa
    98821 ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct tcttcgattt
    98881 catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct aagaaataac
    98941 tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa atacttcttg
    99001 tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat atagctccac
    99061 atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa acagcaggtt
    99121 cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt actttcttat
    99181 ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg gcagtcatac
    99241 atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt actggtacaa
    99301 gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata acagcaccag
    99361 ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc tgacttgcat
    99421 aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg atacaaatga
    99481 atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta ggctcaatat
    99541 aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac cttgctagaa
    99601 tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg acaatcgtag
    99661 gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg aacttttttg
    99721 cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct gctgcattca
    99781 aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat aaggcgagta
    99841 ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa acagcggcga
    99901 tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt ccactagatg
    99961 catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt actgcatttc
   100021 ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct tctagttgct
   100081 ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac cttgttgcac
   100141 aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata tctttcgcta
   100201 attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca atccttctta
   100261 caagataagt atagttctta gaaaacggtt tctccattca attagtaccc cttctaatag
   100321 cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca ctcactgctt
   100381 gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa acacgcttga
   100441 tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt tttgtttcta
   100501 cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc ataactaggt
   100561 cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt tttatttgat
   100621 tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca actatggtca
   100681 gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga acactaggta
   100741 gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa attgcatcat
   100801 attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc cggcattctt
   100861 tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa atactaattg
   100921 gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac gcttcggcaa
   100981 gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa tgtattggga
   101041 agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt tgtacaaaat
   101101 gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata tgggttagca
   101161 aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga ataatcgttt
   101221 gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta atcatcaaat
   101281 aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa aaagaatagg
   101341 gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat aatgtatacc
   101401 tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga taccgagaaa
   101461 atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc tcttttaatg
   101521 tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga ggaaaccttg
   101581 cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt gaattttctt
   101641 cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta ggattgcgct
   101701 cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa agaaagaaaa
   101761 tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac gtcacaatag
   101821 ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct tgtatgattt
   101881 gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta tttgactgga
   101941 taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg atcgttttct
   102001 tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc ttatttctta
   102061 atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac ctcctctttg
   102121 ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag gtttaaaaat
   102181 catttgaaga aagatctata ttcaaggttt ttaccattag actggataat ttgtttataa
   102241 tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt ttgtctatcc
   102301 acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac gatatcgatt
   102361 ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc agcaatttcc
   102421 tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt caattcatct
   102481 ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc ataacggtct
   102541 gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact ccaaggttcg
   102601 ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt atctacgcgc
   102661 atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat ataatctgcc
   102721 gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca gtcttcttcc
   102781 ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc ggagaaaaac
   102841 catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca gtcatatgca
   102901 taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg atcgattttc
   102961 tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc ttgataaatc
   103021 actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa tgtaaccaat
   103081 ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt catccaatat
   103141 ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa aaagtcgatt
   103201 aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt ttcataatga
   103261 ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag tctgtcataa
   103321 aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat tcgtgcccat
   103381 gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat atcctcttca
   103441 aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc gtctaaagca
   103501 atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt catgatcccg
   103561 ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc ttcacattga
   103621 ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg atccataact
   103681 atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat caaaacaaga
   103741 tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt catttttaat
   103801 atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt aaccatctaa
   103861 gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat caactttgcc
   103921 gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt cacgtggaat
   103981 agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct ggtcttcata
   104041 tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat agtctcccca
   104101 gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat aaaaaacaga
   104161 atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat tgactcgaag
   104221 ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca taggcgtcct
   104281 agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg taaatccaga
   104341 agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg cgatatcatc
   104401 gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg tgcctttcat
   104461 catatggagc aagatagcaa acatcttggc actttctttt cgatacacat cgtcatttcc
   104521 ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat tccatccttc
   104581 atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga tactcaaggg
   104641 tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt cgaattggaa
   104701 gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt cggtagttgc
   104761 tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt gattcatttc
   104821 ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg gttctttgcc
   104881 aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc agaaattcat
   104941 catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag gttgacgctt
   105001 gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag cagaaccact
   105061 gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc aaatataata
   105121 gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat gttcatcaga
   105181 agtatgattc accaccagat ccatgatgat acggatattt cttttctttg cttcttcaat
   105241 cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat aattactgat
   105301 atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa ttgcatcaat
   105361 acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc caataccatc
   105421 ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat ggtgccacca
   105481 tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct taatcattta
   105541 ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac cttgttatcg
   105601 gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt ttgaaaggat
   105661 tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg ttcactcagc
   105721 tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt tcgttttttt
   105781 ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat tcaatatcca
   105841 catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt cttttcctct
   105901 tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc catctgaaat
   105961 actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa tctctaagtt
   106021 tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa tcaatgctgg
   106081 tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc ctaacaagaa
   106141 gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga taccagctga
   106201 tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa gcatagctgt
   106261 tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca tgaaacctgc
   106321 ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa gcaagaatgt
   106381 cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta atgcaactaa
   106441 aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg gaatcaaacc
   106501 tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac ctggtacacg
   106561 ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag tagaaccaac
   106621 gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc caccttcgct
   106681 cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt tcaaatctgc
   106741 tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa taaaaatcaa
   106801 agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc ctaaacaaac
   106861 agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg gataacgggc
   106921 taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag taaacactgc
   106981 tccttcatcc attccagaag cacctaatac agttggattt acaaataaga tataagccat
   107041 tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt tcaatttttc
   107101 tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat ccgaacatta
   107161 taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta tcatatacta
   107221 aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac gttccatctg
   107281 attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag aatttcttta
   107341 ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat ttgattttac
   107401 catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc agattattta
   107461 gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt tttcctgatt
   107521 tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc aaataacctt
   107581 ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga cgactcagct
   107641 tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa gatgccattg
   107701 ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa ttcatccgta
   107761 aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg cacaaatact
   107821 tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact cttaaattct
   107881 tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa gaatcggcaa
   107941 atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat catttgaccc
   108001 ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc acgaaagcgc
   108061 aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta ggattgcttt
   108121 cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt cttatttcga
   108181 ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac actagttacg
   108241 ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc acgtgccgct
   108301 tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc cgtcagcatc
   108361 gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc atcatagtag
   108421 atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag gaatgattcg
   108481 ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc ttctccgccg
   108541 caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg attgattggg
   108601 aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga acgtgcacct
   108661 tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc gttttggctg
   108721 aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa taattgatga
   108781 tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga taagatttcg
   108841 atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt tttcatctgt
   108901 tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg ggatcatctc
   108961 ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa aaagcgagcg
   109021 caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt tcttttgctt
   109081 tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat ttttttcgta
   109141 catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga ctcgttcctg
   109201 tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa aaatcggttt
   109261 ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc aagtaatcag
   109321 ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg atactaattt
   109381 gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta ttcacggctt
   109441 cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct tcgctaacat
   109501 tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca gaaagaccat
   109561 ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag atttctgctc
   109621 cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc aaacgttcga
   109681 tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga tctactttga
   109741 tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt actaaataaa
   109801 gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata gaatctagcg
   109861 ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac ctttattttg
   109921 tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat aaaaaaatca
   109981 agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa aagctcaatc
   110041 acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg ttcgcttttc
   110101 tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt cattattctc
   110161 aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat aatactgaaa
   110221 aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact gagtagtttc
   110281 tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag gagacaatcc
   110341 tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt cgattagtag
   110401 gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg gatgtccttc
   110461 tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt cactgatcag
   110521 ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat cttttccata
   110581 atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact tcttgttcat
   110641 tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga agactggttt
   110701 aattacggca aataaatata atgaaatctg caataaataa aagaatgtta aaaaactcga
   110761 gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa agcttgcatc
   110821 tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct ggctgttctt
   110881 attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt ctcctaccaa
   110941 ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt tgaaattgct
   111001 ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc gttcaaaagc
   111061 caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc tttttctaat
   111121 ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa ttcatatagt
   111181 gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa tgcttctttc
   111241 gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg ataatgatcc
   111301 atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg ttgccataac
   111361 acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct atctgctaat
   111421 tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat cactttcttt
   111481 cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt cgtcctttct
   111541 tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta ttccttgatt
   111601 tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt cataagatat
   111661 gtttttcctg taccaggact accagccaga agaatgaaat actttttcat ctcatttatt
   111721 tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct tgacaatttc
   111781 ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga tttctgtttc
   111841 actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc caacattgaa
   111901 tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac ctgttcctcc
   111961 atggataact agggggacat caactactgc atcgatttct ttcagcaagg gaatgtttac
   112021 ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta atgcatccac
   112081 gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct tgtcattttc
   112141 agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt ctacggaaac
   112201 accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt ctttgaaagg
   112261 cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt ctttgatatc
   112321 atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt cttctgcaat
   112381 agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat cgacacttgt
   112441 ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag gaagcatttc
   112501 taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg tttttgttac
   112561 ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg tttcctttga
   112621 tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag taatcgatcc
   112681 cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg ctcatcagtt
   112741 ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa tattggatgg
   112801 cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa agtttcgcta
   112861 atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc tctgattgaa
   112921 tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact tttttcggtt
   112981 ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat taaaatgctt
   113041 tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta tctacatcgg
   113101 ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa gcgggcaata
   113161 atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt ccgccaactg
   113221 cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata ccaggtaaaa
   113281 tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca atcgttgtcg
   113341 taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga caatctaagg
   113401 cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc acgatttcac
   113461 ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat tggatggctt
   113521 gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg aatggttcgc
   113581 ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca gacaaataag
   113641 tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac tttttatttt
   113701 cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg atcgtacaaa
   113761 aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt tgcgctactg
   113821 ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc aatacgatcc
   113881 ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat aaaattgctt
   113941 gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata ttgaatacaa
   114001 aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc attgcttgac
   114061 cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca gtaaagattt
   114121 tcccgaaata agttaaactt ccaacgatga tgctcgaacc agcactcaac acttgaaatc
   114181 ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc tgcagtagta
   114241 gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata ttttcgatga
   114301 taaaattgat aacgcccatg tttttaccct cttttctttt tgtatttaga taactccctt
   114361 atcttgcaga actggggtga ttttttcttc aatttcattt tttgaaacaa tatttttcaa
   114421 atagatcatc gccgttttag gatcaactgc gaacttttcg aactgcgaac gaaaattttc
   114481 tgctgtgatg atcacatctg gtttcatgga aactgcggaa gaaatatcac aatggtccag
   114541 tttggcttct actcctaatt tgttcaaaac atcctcagca gacatctgtg ctgcaaaact
   114601 acttcctaaa cctgcaccgc atacgaataa aatgttcaat ttgttcatct ttgttctccc
   114661 ccgtatcatt tattatttct caactactga aaaaagcagt tgtttgaaat cttcgatatt
   114721 tgtgcattca atcaatcgat ccaacttctc ttcgttgttg atcaattcaa ttagttcttt
   114781 catgatgttc agatgcgagt aggagtctac tgctgccaaa caaaaaataa tctttactgg
   114841 atccatttca ggattaccga aatcgattgg ttgctcaatc gtagctacgc tgactcctaa
   114901 tttattgacc ccatcttctg gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat
   114961 atacggtccg taatcattca ctgcacgaat catcgcttcg acatagcgct cttcgacaat
   115021 gttttcttta accaatggtc tagcagctag ttcaatcgat tcctcccaag tagtggcttt
   115081 ttctttgatc atgatattgc tgtccgtcaa aatatctttt aacataggct ggatctccct
   115141 tttgttgatt tctaaattgt ttgtttcgaa taatttttct aacttgccat agatgattcg
   115201 atctactcgg ccaccacttt ctttcatgac atctattatt tgagtgaata actccgtcga
   115261 ttcatgactg ttaggctcta accgctgtag ttcttcattt cttttcaaaa agtcttctat
   115321 aaccaagata ttcgtctcag ttaaaatcgg atcgacaact aaaagcggct tatttcgata
   115381 attcaattga aaggtgctga aaaccagatt gacatccaat ttatctacta attcgatttc
   115441 ttttgaactt aaaactgcag taatctcgat ctgaggaaac ttttctttca gattctctgc
   115501 taacagattt ccagtagcca tcccatggtt acagacaacg actgatttat aaacataatt
   115561 caagtctcgc ttgattacac tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc
   115621 gtcctccagt atcttgccac caattacttc ttcgatcgta ggaacaaaat gagtgactgc
   115681 gcggtagatt gggaaataat ttgttcggat gttttctttc aatggattca tgacttggat
   115741 atgattcttg attcttacaa tcagtgcagc catgtgctta tagagatttt cgaataaagc
   115801 ttcttccttt agatggaaag gtacgtgtgt ctcgttctct acaaattgga tcaattggat
   115861 cgttagtaat tgagcttgta cccactcgat tgaattggag atatctctag cattgaacgt
   115921 ctcaatagtg aaacgaagat aatttctttc tacttgcggg acattgtcca attgaaattc
   115981 ctcgatcatg tggtcaataa atgcagaaaa gctactgtct tttatttctg tatttttcca
   116041 attaatggca gagataaatt catgtttcct gattcgctgg atccagatca atgtaaaaag
   116101 caggatttgt tttttataaa tatcatcttc ttgtttcaac aacttattgg aatagatctc
   116161 ctgtattttt ttgatttcca ccaaaggaaa ataatggaga aagatttttt gagccggtgt
   116221 taattgtgca tcttgattca taaagaagtc ggtcattccc agattctgat tgataaaatc
   116281 atagatcatc gtacggatag atcgttctga acctttataa accagtcctt gctttccata
   116341 actgacgatc tctatcccat aactgaccag tgttgctcgt aaccgtctca tatcttcatc
   116401 taatgtactt ttagagattt gaaattcttc ttcttttttg tttagatgga tcgggattcg
   116461 gctgtaagca acggctaaaa ctagatcaaa aatacgttcg cgccgattca aaaagccgtc
   116521 tttcacatct tttatttcag tttctaatcg agcttgcttt tccttttcca gcttcaacaa
   116581 aaaacctttg ttgcgaattg tacggatctc cggaagcttt ttactgctca accagatatt
   116641 cgcttcaaga acttcctgac ggatcgtccg ctgactgaca ttgaactcac ttgctagatg
   116701 ttttgctttt actggatatt gggctgtcat gattctgtga agtatttcaa ttgttcttgt
   116761 tttcatagaa atgatctcct tctgatttca agtatatggt tccgcttaca taataaaaag
   116821 tagatatttc tgccacttga agtggaaaga aagtaagcaa agcaaacaaa aaataagcca
   116881 tatgcttttt catctcctca acgaaaaaga catacgccta ttattacaaa aattttgccc
   116941 atctatacaa aaaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa
   117001 actaaaatag tgcttcctat ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt
   117061 taaacaccat ttagtggaga ggttgtgaca gagatgttca gccttgagcg ataagaagcg
   117121 attttgaaaa atcgcttccc atattttaca aaatcgtgcc ttattgccga taggctatct
   117181 ctggcacacc gtttattcag aaaaaggagc tgcgacaagg cttttgtcac aactccgttc
   117241 ataaatattt cctgtcaatc cagcataatc ggctgaataa aatcggcttg ccatcttttt
   117301 tctttctcag aaaaatcaaa ataccatatc tgagaaaaat actgtcgttg tgtcttactt
   117361 cctgagatca atcgcccatc ttttcgatcg actgaataat cacagcatct gaaatcaatt
   117421 cggatggcaa aactattttc gtggatctgt cgataatttc ctacttcctg aatagttatt
   117481 tttttagtat gatttcttac accgtctgct ttgttttttt gcagaacttt ctgatgttcg
   117541 gcaaacagct tgtctgtata acagcttctg gctttttcag gagtttcttc ttcccaagcg
   117601 gattggatct tcatgaatat cttttggatt tccagaaact gtgctttctt ttctttagcc
   117661 gttcctgaca tgcgggacaa tatctccgct ttcagccttt tcttttgtct tttattcttg
   117721 acgatagaaa aagcagaaac ccctcctact gacaaaacag ctaatgcaag aaatcccgtt
   117781 tgctcataac tagaaggacc tgtacctgga ccataatacc cataagaatc tctgccgtaa
   117841 gaacgactgc caaaataact gcccccatat gaacgaccac caaatgaacc tctgcccgaa
   117901 cttcgaccgc tagatgtacc tccaccatga ccacccgcga cagcgaatcc ttgggtcggc
   117961 agagcaaaca aacataggcc cactaacaaa atgattgcta aataattgat ttttttcatt
   118021 gtcttcctcg ttatctttta ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa
   118081 gagtcaataa ccagatgcat aaactgtttt tttagcaatt ttgtcttatt tagtcattga
   118141 gtaacatcgg acaaatgtat gtgtcggcag tccataattc ctctatcttc agcatgaaca
   118201 agcttgcaga caagagatct gcgcttcctc caggagagat ttggttttcc tgacaaaagt
   118261 gcaacagtgc tgtaaatgga cgatttggta aagcactttg actagcagca tgagcaagtt
   118321 tttgcatttc cactaacgtt ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg
   118381 aactcatcaa aactaacaac atatgcattt gtttctgtac atatgaatca ttatctagct
   118441 ccttagctgc ttgaattgca agcctgatat gcggataccc taatatcgct tcttcatatg
   118501 caccatttac gccatatttt tgcttcaccc tatgaccatg agtggttttt ttatgacgat
   118561 attttgtatc aggaaaagca gcaagcttgc tgacatcatc aagtattttc gataaagaaa
   118621 aaggctgttc catactgatt ttttgtgcaa tgacactgat caatagcccc attgcccaaa
   118681 tcgctccttt atgggtattg atgccatttg tagcaatcag cattgccttt tccgcttttc
   118741 gcccaatctc agcaattctt tctcttaact cctgatcaat agcatgatgc catgctattt
   118801 gagccatttc ttcaaaaaaa ggagttagcg tcttagcaga cttaagaaat aaagcatagt
   118861 ccatatcgga atgtgcaccc gcatccagtg catccactaa tccaggtttt ggacttaatg
   118921 ttacttctgc gatcaatgct tcctctacca acgcagcgag ttgctgagtc actgcttttt
   118981 ttcgttcgtc atttatcatg acactcactc cttcttccta ctattacttg ctgaaacctt
   119041 ttttgatagc tacccaaatg atatgaagta accagcttaa agcaaatgca caacttgccg
   119101 tcattagata agctacaaga atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa
   119161 acaataataa cagtacttgg aaaacaaata cattggctaa atacgtacga taagcataaa
   119221 cagacaacca tttgaacaat ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc
   119281 ctatgaagac agcaaagatg atgactaaac tgtataaact ttggatcgta ttcaagtaag
   119341 gtgcattcgc aaagctcaag tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg
   119401 cgataactaa ggcaacaggt aagaaaagat aacgtactct gtccaaatat tgatagactt
   119461 tttcgtgata aacaaatgcg gctaccccat aaatcatgaa actagcaaca aaccgatcta
   119521 ataagtacca gctgtcatga taaggcccag tcaatacttg tgtttgatag aacagatacc
   119581 atgcgacata taaaatcgtt gaaccaatca atactggcca tacatatttt ttattagcaa
   119641 atactttgta accgagccaa acaaaaaacg gcatgaacaa ttggatctgc agcatcataa
   119701 cggtatacca taaatgaggc gctccatcac ctgtgacata tttcagtaaa aagcttgcag
   119761 tatccgtata cggagtttgt tgttggactg ctggaaatag ccaaagataa gccgtcgtcc
   119821 atagaagata cggaacgact agttcaaaaa acttttcttt caaaaattcc caataagaca
   119881 aatgctgact tgtttttacc atattataaa caattgcaaa aataaacatt ggtgctgtgt
   119941 atttaacgat gacgtaaaag gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg
   120001 ccaaagcaaa gctcaatatc gtttgcatca taacagccgt tacagctgat actttctgga
   120061 agtcacttac gttgattttg atttttttgt tttcaaacat ctctttctct ctctttttct
   120121 ttattaccaa agttctttgg ttaatttagg tccttcgact gttttcaata gaattttttt
   120181 ctctggctct ctcaaatact cttttagtga aaaaccgcct tgccgagtca ctacttgggt
   120241 atcgaattgc tcaaaaaaag caggatgcga ttgaattacc tgaattggca attcaatcgg
   120301 tgaatttgcg tacagcagca aatcaaaatc actggtttct tttactgccg gaatcccagt
   120361 cgataattca aatcctaagc tgccgccgat tccccattta catcctgata atatgtttct
   120421 agcagcatga aattgctgat aaacaggata atccatgatt ttctcttgtc tatacgattc
   120481 ttgttcgatg atgtcccacg gatgaatgac ttgtttgacg gcatgttttg agatttctgt
   120541 tgaccatctc tgattgcggg caggtccacg taaaccaatc ggtagtattt ctgcgtgatc
   120601 cgtcgacgca cgacgaactg ttccgaacat cttttcagtt agaacgaccc attcaggcaa
   120661 ggtgaaccct tctatttcat gtttatcaaa aaggacaata tcatgtgctt gaatcatttt
   120721 ttatgcatcc cattcttcgt ccattttggc acggacttta tttgtttcga cacgtccgaa
   120781 tgttttggct gtttcgtttg tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac
   120841 atcttgaatg gcttcattga ttgcttcgat gactttgctg acattttgtt ctgaagcagc
   120901 ttggtcggtg atatcttcta ggaaatgata gatcgctcct agttttgtat aattattgat
   120961 atcgtaagcg atagctggaa ctttttcagc agctgcttcg atttcagcaa ccgaacgttt
   121021 tgtcacacgt gcagcacttt ctttagacat cgcttggacg gtaatttctt tattgtttaa
   121081 agcaatcaag cggcttgatt gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc
   121141 tgcaatcaat ccaataactg gatgtccagc ttgacggagt tttgcataag cagcagcact
   121201 attagccaaa gccacatgga taccgatcaa ttcttcgtta tagccgtatg cttggcttgg
   121261 tacatcgatc acaacgatga ttggccgttt cacttttttg tctttatctt cttcgtaaac
   121321 gtgatccaaa atttgtccca tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac
   121381 acggtacatc gggtttttag gatcaggtac gattgatgtc acgatggctt cttctatgaa
   121441 tttacttgat ttaccataat acacagtact aatagaagaa gttggatttt tcatgccagt
   121501 tagtgccgca aaccaatcgt aaccaacact tgctgcagct ggttcatttc cttctgctac
   121561 ttctggtaag tcaattgatt ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat
   121621 ggccattggt tttgaaagat ctaaagaatc aagtaatgat aaataaaatg ctgagctttc
   121681 actgcgatgc gtgtcttttc gttcgtccat tgctgcgatg acagcagctt tgattgcttc
   121741 tacactatca gtcactaatt catcaatgat ttttgattct acccgttgac gagatcctaa
   121801 tgtattccaa atcaagtctt tgtcactaga atcaaattct cgaacgcctg cttcttgttc
   121861 aataacttct ggtccattca aaccgactct cgcttttttt gttgcgatta aataactcat
   121921 taatgctgaa gtaatcgaca taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat
   121981 gactggtaca tattgtttta gagcaatgat tacatttccg atttctgaaa tagataacag
   122041 tccgtagttt gcttcttgca aacgaacacc acctgtatct agtacaatga ctggaaagat
   122101 ctcatttcct tttttatttt cttctaacac atgttcaagt gcagcaacga tttttgcacc
   122161 ggaaacttca ccgataccgc caccttggaa ttttccttcc atagcgatta ctactgcttg
   122221 tttgccattg atcgtgccac ggctgacaac gatcccgtca tcactttcag ggacgattcc
   122281 ttgtgctggt aaacttggcg cgatgatttg atcgaatgga tcaatcaatt cacgtccatt
   122341 gtcaagtaga gcgttcactc gttctctggc gtttaattct acaaaactat ttttcatctg
   122401 aaagttcctc cattgcttgc gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt
   122461 cattgatcac gatatctgct gaaattggat aacgatcaaa aaatctcgtt aatacattgt
   122521 tccatacttc gccgaagcca tcgcttcctg tacaaatttt tacagtagat tctgtttttt
   122581 ctgttggaaa catcaagatt tccaaatctc ctgaaccgac cactcctaca tggattttct
   122641 tattgatcgg ctgtttcgtt ggatatttat aagctaattg ttccatggat ctctcccctt
   122701 tttgtaaaac agagcataca cgttctgctt attcgtcttt cttcttccat ctgggtaaat
   122761 ggcgacaaaa ggtttttctc gccaatttta tgaccaagtt ctgaatttca ttggtggttc
   122821 atacaggcca tctgaccatt cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg
   122881 tttcgcttca ctacgtttga tgcctagatc ttctggtaat ttcacgatgc cggctgcacg
   122941 caagctatct agtgattctt tcgtgctagt cattccaaga ggtgtaacac cgccaattgc
   123001 tgcaattgct gcttgtcgtt cttcttttgt ttttgctttg tacaaataag caattccttc
   123061 ttctgtcacg atatgtgtag tatcttcgct ataaatcatc actggtgcat tggctaagcc
   123121 tgcttgtttt tgaacagcta gtgcatctaa ttcttcgaca aagactggtt ttttatttga
   123181 accatatgtt tcaaccattt gaacaactaa tttttggcct ttccctaatg gatcatcatt
   123241 gtcgcgaagt gattgccatg ctggtgtaga atgacgacga ccgccaggat tatgtcccat
   123301 gttaggcgca ccgccaaaac cagataaacg tccttttgtt acggtagaag agtttccttc
   123361 gtaatctaat tgcaaggttg aaccgataaa catatcgatg gcatattgtc ctgcagcttg
   123421 tgataatgtt cggttactgc gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg
   123481 agcagcaata tatttttcca taccaacttc gccaccaaaa ctatggatgc tttcaaccca
   123541 acctgattcg atggctggaa tcatcgttgg atgtgggttc aatacccagt tcttcgcgat
   123601 tttccctttt aaccctagtg attcaccata agttggcagt aacaattcga tagctgctgt
   123661 attgaatcca ataccgtgat tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat
   123721 tgccatcatt gccattagaa tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa
   123781 agcttctaat tgataaggtt tatctgcttt cacgacaacg tctacccagt caccagggat
   123841 atctacacgt ggtaaagaat cgacaacttc gttaacttga acgatcacga taccatcttt
   123901 gaaagctgca gcttcgatga ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt
   123961 gccgtcttta tctgctttat ctgcagctac taaaacaaca tttggaatca aatcgatgaa
   124021 taagcgtcca taaagttcca aataagtatg gatatcacct aatttcattg tgccgtcttc
   124081 aatcatttgg gcgacacgca agctttgtgc accagcataa gagaaatcga tcttgcttgc
   124141 gattcctttt tcaaaaatat tcaaatgttc tggtcgtgag atactagaca tgatcaaatg
   124201 cagatcattc actttttctg catctacttt ttcaagactt tctgaaagaa aacttgcttg
   124261 tttttgattg tcgccttcta atacaacttt gtcgccggga gcaatcagtt tttccattac
   124321 ttctacgatt ttttcagttt ctacatactt gccattgagc aagttgctga ttttttccaa
   124381 tcgctgcgct tttttttcgc gtttagaagc ccagttgcgg tttggttttt ccataattag
   124441 tcatctccat ttttgatata gaaacgtggc gtcatcaata ccatgttggt ctagattgat
   124501 cgtacggatc cctttatcta caccaaattt tgtatgaatc agctttgtca aagtattgcc
   124561 ggggggaaat tcaatcgtca gatccattcc taattctttt gccaagtcca tcatttggtt
   124621 ccactgcaca gggaaagcta ggttttccaa caaatcttta cgaatctctt ctgcgtcctg
   124681 agtggctctt ccatccgtat tttttatata caaacatcta gcatcagata gatggacaga
   124741 ctgcatatac ggcttgaatt tcttgaccgt atcattcatc aagagacagt gagatggcac
   124801 agggactttc agcagcttcg ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac
   124861 ggataaacct tcgatactcc cagataacgt atgttgcatc ggacaatttt catttgacag
   124921 ataaactgga tggtcaggat caaatgtttt tgctacaatt tcctcagctt cgcttctcgt
   124981 cacacctact actacgccca ttgcataacc gcttggataa gcttctttca ttaagactgc
   125041 gcggtgatag actagttccg ctgcattctc aaatctcaaa gatcgacaag caacagctgc
   125101 acaaaaagca ccaatcgaat gtcctgctgc aatatcaggc tgaataccgt ttttttccat
   125161 ttcatctaaa taaaatactg cttttgtcag taatgctagc tggataaaaa ccgtatcttg
   125221 atagttttct tctttatcaa ctaaccgata ccccgtcaca ttttctaaac gttccatgta
   125281 catttcaggg atatccgcta acatccctaa cttctgactg ccttgtccag gaaataagaa
   125341 acctgtactc atgagcctcg cctcctcagc acttactttt tccactgcta tcttagtcaa
   125401 tttctgctat aataaaaaat gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg
   125461 gatggataat tatgaaattg cttcatctgc agtattttaa aaaagtattc gaaacaaaaa
   125521 atgttaccca agcagccaaa gaattattta tttctcaacc tgccttgagc cgtgcgatca
   125581 aacatttgga aaacgaatta ggtgtccctt tgttttacca tagcggcaga aacattgaga
   125641 cgaccgttta tgcagaagaa ttttatccat atgcagtcaa gacattagac acattagaag
   125701 aaggaatcaa attattgtct tcggtcaatg agaagatcgt tacttccgtc atattgtatt
   125761 tagaggtagc ctctgtttct attccgaact tggtccgaat ttttatggaa aagcatcctg
   125821 atatccaatt aacgatcatg caacatcatt taccagatga tattaccgat cctgtactgt
   125881 acatcacttc ggagatgaag cctggcatga ccaatattcc tatcatgaaa gaacctgttt
   125941 atgtcgccat tcctaagaaa catcctcttg ctaaaaaaga acatctgcaa ttagaagata
   126001 tccaacgcac ccccatcttg atgctgtcaa agagcaacgc cttccgtcat acactggatg
   126061 cagcacttga agcgaaaagt atcgaattga cgatcagttc gacgacagat gatcctgcga
   126121 cattacgttc tattgtcaag caaggattag ctgttagctt tttcccaaaa gtttcttggt
   126181 cttacgataa aaatgatcct ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa
   126241 caatttattt atcttctagc ttcacagaag atcatccttt gatcaaaatg attgcaaaaa
   126301 cgatgcggga attttattta ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg
   126361 cagctctttt ttcgaacaaa cggtgttcca gaagtaattt cttagaaaat aagccgaaat
   126421 ttcccaaaaa tttgagaagc aattttcgta aattccttct tatttcttga agctaaacat
   126481 ttctgtcaca acctcttctc tattgtccta gacattcatt gcgttgattt aaaacttcca
   126541 tcaatcaaat ctgctagttc atctagcttt tctattttac gtagatcaat agagatccaa
   126601 tgttctttat tcatgtgata ggctggaaaa tacccctctt ttcctcgcaa aattccgcca
   126661 agttcaggat cgaccttcaa atcaagaata ttgatgatcc tatggtcact tgcatcatca
   126721 tagatttttt cttctggaac agacatcagg accccaaacc attttttgct tttttgatgt
   126781 ctgaatacgc aataatcagg aaatttttta aaaatatatt ctggagacaa attgtatgtt
   126841 tcattgatgt gatcgattag ttcttttttc gttagcatct gcttccatct ctttcttatt
   126901 gattcgcttt attcaaagat accacgtaag aatagaaaaa tgaatacaag tagttgctaa
   126961 tcaaatactt cgatattttt cttttttatc aactcttaaa tgttcaatcc gcctgtgttg
   127021 gtcttgctac catctactat taaaatgttt attattgttt gcccacctat tttttgattt
   127081 tagtggtatc atttttcaag ttcatgatga aattcttatc atcagtaaat gctccagaaa
   127141 aataaacaat gattgaaaaa tcagttgaaa cttgaccacc gtttattttc tccgtattct
   127201 tagaatagaa gggagtctga ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag
   127261 atattcgacg tcatgtttct ttagtagaac aattgctgaa tcatacaaag ataaccgtaa
   127321 atgaattagc tgaaatcata gggacaaccg aacgaacgat tttttctgac cttcaatcta
   127381 ttcgctctca gctgcccgaa ggctgggaca tcatcagcga tcaagcagga atcagtttgc
   127441 aaaaccagca aaatttatta acaaatgacc tttgggagat ttttttcaaa caatcagtca
   127501 gtgtcgaact gctgaaaaat ctgcttttta caaaaaaagt tgctgtccct gattttctag
   127561 ccgaccatgg gctttcttat gggacattga aaagacatgt gactaaaatc aatcagcgtt
   127621 tagcaagtta cgacttgcag atcgatttga cgaaatatac agcttgtatt cttggaaaag
   127681 agcgtgcgat tcgtactttt tatcatcgat tgctgattcc tttcactcat aacaactatt
   127741 ttttcgagga ttattcgatc catgaatccc attattttca atttttaaga aacctcagtc
   127801 aaactgaact agcggttgaa acagaagaga ttttcggaac atgttggttc tttatcaata
   127861 cgatccgtat aaaagcgaat tgccgattag attcttctat ccataccaac agcacactct
   127921 cctccctgta tgactctgca ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag
   127981 acactgagct ttcttttgct tctttctgct ttctggaaag ttggaattac aacaataact
   128041 atggacaaga aaccgctcgc tgcctgcatc attctccatt tttagaggtc ctcgaaacgt
   128101 ttgtagagga actagcttca gagctgtctc ttgatcaact aaaaaaaaca tctctgactg
   128161 ataacttggc tctcctcata ttaaaatatc atgaatcgcc gatattgatt gaagcattgg
   128221 accgtcaata ccatcgtttt ttagaaacat atgatcagca atatgcacac ttgtatcaac
   128281 agaaagagaa tttactgaac gatctaaaaa aagaaataga aatcaatgaa ccaaattact
   128341 ttctccaact cttgtctcta ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt
   128401 tcaatgtcta ttttattttc caaggagaac cttcatggaa ggcgttcttg cagcaggaat
   128461 taaaagatta cttaggaaaa cgtgtctgct tcttacctat cgaactaacc gatctttcca
   128521 ctatttcttt tgaaaaaaca gatatcttga tttccaattt ccctctagat tctctagata
   128581 tccctattgt atacatttct tctattccaa cgaaaaatga gctcaatcgt ttgactgaac
   128641 tcactttcaa aactttttta tagtaacggc tagcgactgt attctctagc tgttttttct
   128701 tttttgcgaa acagtttgtt catgatccct ttttctattt ctacaactaa gaatagaaga
   128761 atcacatttg ctccaatcaa taactgttgt gtcatcgtta aacttactgt accgatcagc
   128821 tgctggccga ctggtagaaa aataaccatc ccttgcaata aagcaaggat acctaatgaa
   128881 agaaaaagcg ctttgttttg caaaagacct tggttcaatg acggcttgga caactctctg
   128941 caattgatca tgtaaacagc ttgagctaag acgatatttt gcagaagaat ggtttgctgt
   129001 aagctttgcc cttcaaactg catagccaat aaataggcag gaaccatgat cagtagggag
   129061 acatagatga tccgaaacaa atgataacca gataggattc cttgctttgg atctcttggt
   129121 gggcgcttca tgatttctgg atctggcgac tcgaacccta gtgcataaga taaagtgatt
   129181 gtcgttacca tattgaccca taaaatctgt actggggaca aaggtagcgg gcgattcagc
   129241 ataagtgccc aaatcaagat caatccttga gctaatgcag ttggcaagaa gaaattgatg
   129301 gttttttgca aattatccaa aatccgccgg ccctctttta cggcttttgc aatcgtatgg
   129361 aaattatcat ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt
   129421 cccatagcaa ttcctacatc ggatcttttc aaagcaggtg catcatttac gccgtctccg
   129481 gtcattccga cgatttctcc atttttctgc aaagctttaa caattcgcag tttatgttct
   129541 ggtgtcgttc gagcaaagac atcgactatt ggcacttgct gaatcaactc ttcatcagac
   129601 ataagatcca aatcgatccc ttctaaaact ttggcagtat gttttaagcc aatttgttcc
   129661 gcaatcgctt ttgctgtgtc tttgtgatcc cctgtaatca ttttcactga gatccctgct
   129721 tgttggcatt cctttacagc tttgactgca ctttcttttg gcggatcgat caatccggcg
   129781 atccctgcaa aagttaattg ggttaaagtc tcatgcgtga gttcctgttt cgaatctact
   129841 tttttataag caaatcctaa aacacgctga ccttttctcg caaattctgc agctgtctga
   129901 ctccatgctt cttgttctgc agaagaaaga gttgatttag caaataatac ttctggtgca
   129961 cctttgacgt aaatcaccgc tcctttttcc tccgcatgca tcgttgccat atatttgtat
   130021 tcagaactga acggaatctt tgcttctatt tttttcaaag gtagattggc tgtttctgtg
   130081 tgtcgaatca gcgcaacttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct
   130141 tttgttttta attcctgaca gtttttcata atggacaaca cgcaggcttc ttcttttgca
   130201 gctacatcca caactgtcat ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc
   130261 actgtcatag aacctaatgt ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt
   130321 gccatttcat gtactccaac ggatagaatc atggtcaaaa cagctggcaa tccttcgggt
   130381 accattgaca ccaccaaagc aatcgtagcc gaaagaagaa tatgccaatc cataccatat
   130441 cgaaatgtcg taaaaataac taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt
   130501 ttgtttaatc ggttgatttt tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat
   130561 gcttgattga ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca
   130621 gaaccagatt gtacaagcgt tcctgaaaaa cccatatttt tctggtcgcc gatcgattct
   130681 tcttctgtca aaacggcatg acttttttca gatgcttctg attctcccgt caaaatcgat
   130741 tcttccacta ataaatcatg tgcttcgatt aatcggatat ctgctggaac gacatctccg
   130801 gcacgtaaga caatgacatc tccttttacc agttctttcg cagggatttt ttcttgcatc
   130861 ccgtttgata gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caatgattct
   130921 tccgcttttc tttcttgcca gtaactaacg agtccattga cgatcactac gaataaaata
   130981 atacttcctt caatatattc actagaagca aatttcaaaa aagaggcaat gatcaacacg
   131041 atcatcagca gatcagtaaa atgctttgct atttttttcc atcgttttgt ctgctgcctt
   131101 gcttttattt cattatatcc ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag
   131161 ccttctgttg atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc
   131221 atcctatccc ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg
   131281 tatcgattat ttcagggggg tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac
   131341 tgatatttct attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca
   131401 ataaaaaagg aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa
   131461 aaaacaccaa caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa
   131521 taaattgaac atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca
   131581 tgcctgccaa aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac
   131641 cggcaaaaaa taacattcct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa
   131701 gcgcacaaaa ccaatggggc aaactttttt cttttgctgt ttgatataaa atcctgctag
   131761 tactgtagac tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa
   131821 ttgctgctcc gccttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta
   131881 aatctaaaca atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa
   131941 agagaatacg ccaaggcaga cagttgattg cttttttcaa attcttttgc ggatcacttg
   132001 tctcgccaac ggttaagccg atcatttcaa ttccagcaaa actgaataaa accataggaa
   132061 atgagactac cattccagca aagccaaacg gtagtaattc atcgatctgt ccaaaatttt
   132121 ctttgattcc gatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga
   132181 taaaaaggaa aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc
   132241 acttgactgc aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca
   132301 aagctggtac atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa
   132361 gtccagctcc aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc
   132421 ctaaataata gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat
   132481 cacccatggc ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa
   132541 cagctggccc tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg
   132601 cgccacctaa tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt
   132661 tttccatcaa gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa
   132721 ggtttcttta ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg
   132781 actgcaatta gattgatcca tgttccagct ttcatcgtca gtccgacaga aaatccgatt
   132841 gccgcaaata aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt
   132901 ccaattctaa atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc
   132961 cccatgatga catagacgat acagtagata acagtagttg aatttacgag catcaaaaat
   133021 gcttgattga cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac
   133081 tgagtcaaaa taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt
   133141 ggtggatacg caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa
   133201 gcagataatt ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga
   133261 tgtggcaaac caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc
   133321 atttgtcctt ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat
   133381 ataaaaatta acgcggcaaa tactccgcga atatacgttt taactggatt ttccaatcga
   133441 gtgatataca cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa
   133501 acaaatgagg atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat
   133561 gttccggttg gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc
   133621 gtcaaaggca cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca
   133681 aatttcaaat tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat
   133741 ttgctgttca aaccaagcgg cacattatcg ataatattac caaacaacgg agcgagtgct
   133801 gaagcgacca tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac
   133861 ccccattttt ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac
   133921 attccagcaa attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc
   133981 agcatgtaaa aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt
   134041 gctacaaggg cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca
   134101 gtatctttca tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt
   134161 ttgttcaaga acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga
   134221 aacatccatt gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt
   134281 atagaacgtt ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat
   134341 acaattgttt tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc
   134401 acacaaaaat cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat
   134461 tttttttgta taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc
   134521 acgtagcaga gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc
   134581 aacaaaacga atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat
   134641 aaaccgttca ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt
   134701 taattcattg atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat
   134761 attaaaatca ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt
   134821 cagatgatcg agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg
   134881 accatatccg gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt
   134941 tgctccagct tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga
   135001 tttttcaaac acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat
   135061 tacgattcct ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga
   135121 atccgcttct gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg
   135181 gtggaaaaca tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc
   135241 tgcttcgttt agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata
   135301 gaaatagatc ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc
   135361 tacttgacct tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg
   135421 tccagctaat tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg
   135481 aactgggata gcaaccatct gatctaagcc gactccgcaa atatctaacg ccttcatcca
   135541 agaatagtgt tttgtttgag ggaccagcca tttccctaat ctttggatat tttttccgct
   135601 acgggaagaa gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc
   135661 caaaatttct tcaacagata aattcaaaag ttcccactca gacatttttt tcactttttc
   135721 aggcagcact tccttgacag ctaaaggaat cgatttgatg caacgggcgt accataatcc
   135781 ttcaagatta gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa
   135841 taatgaagca aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc
   135901 caatgcaaca ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat
   135961 caatgtttca gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc
   136021 tgcgcgtaat cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag
   136081 ataatctgga gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt
   136141 ttctctccat ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc
   136201 attttcagct ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc
   136261 ctccatattt tgttggtcaa tgtcttgcag atacatgtgt ttatctgtaa cacctcttca
   136321 ctatagcgcc aaaaatgaga attttttttt tataacatca aatccacgta gatttttaca
   136381 aacaaaaata aataaagtcg gatttttctg ataattcaac gcaaaaaagc gaacaatttt
   136441 tcaataaatc agtcttctaa aatagataac ctaaaaaaag cgaacaaaca aataaaatga
   136501 ctgtccttca ttcactaaac atatttttat ttttttatat tgttaaaaat tcgcaattta
   136561 ttttttaata gaattatctg ttttccaaat tttataacat aaaaaacctt ttttaacggc
   136621 atttatatgc tttttcagaa attaactgat gatttcaaaa agaaaacatg tcataatatt
   136681 tcccatattg tgcaaaaaaa tacaaggcgg aggctctact atgattgaag aatatattga
   136741 gaaaaatatt ttaagacagc tgtttttatg tgggcaattc tatgtaaata aagaagtcaa
   136801 tctagaaaag ctctccaatc tcctgcatgt ttgcaaaacc actttactca atgatatcaa
   136861 taacataaaa aaagaatttg aagaacagat cgcttataca catcgggaaa aggaccgtta
   136921 cactttatat ttttcagaac atatacctcg atgcaagatc atgcagcaat tgtctcaaaa
   136981 ttcgttgttt ttaaaaactt gtctgcttta tttggaagaa gatgaacctg attatcttca
   137041 attaactgaa tgtgaattca tctctgtcag caaagcttat tcattaaaaa aacaagtatt
   137101 agcttatttt aatgactgcg ggatcgaaat cgaccgctac tcccctcgat tcactgaaat
   137161 ggaaagacgt ctgctgcttc ttaatgtgtc gtatcgttta ggcggtttta attcttggga
   137221 gctacctgaa tcgttttttg aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag
   137281 tggcagattt tatgataaag aaaataaaga aatcttatcg attggttttg ctatcagttt
   137341 cctacgccag caagtgtgtg ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa
   137401 acgtcctatt tacaattatg tcgaatcagc atgggaaaac actgatttcc aaacctatta
   137461 taaaaaagaa gaattcgcct ttattttgac actattcaat ctttgtaatt atggtttcca
   137521 ttcttatcag ttgattgcgg aagactttca acagctacac caagtgttta ttgacaatac
   137581 tcccgaaata aaagaactag ttgctacctt tgaatctcac ttcaatcaag aattattcgg
   137641 aaaccaaccg ttcgaacgtg cgctgattca tctgatgcgt tcggcttggg ataactatca
   137701 attattcatg ccagaaaaat tttatctttt aaatgaggaa cagacaaatt tatataaaga
   137761 agtccagaca attttttcca gctggtccag ccagttacct tatgatctac ggttgaatcc
   137821 taattgcatg cgggcttttg tgatcgaatt gagcggaatt ctccgtctga caaaagaaca
   137881 tctgactatc tatatcgtca caaattcgga tgttcattat ctgatttatc gggaagcctt
   137941 ggaagctgta actactttcg attttcaagt tgcaccaaca atttattcaa gtatatctga
   138001 tataaagaag tatgcgcagc agtcctcaaa ccgggtatta tgtgaacgta cattatatac
   138061 accagatgcg gtccaatatg aaaatattat tcctatttcg atcaatacga tcgatcgagc
   138121 tatcatttca gctgtgcaaa acaaataagg ggctgtgaca aaaatcatgt cacagcctct
   138181 tatttgttga agatgcccat ttctgtaaca atctcttgat acacgtcagg ctcacaacct
   138241 cacttatttt ggacatctac gggtccgatc tctttattta aaaaataaga aatgatggtt
   138301 cggataacta ccaacgccgc tagttggaaa atatcctgca aggtaggttt gataatcgat
   138361 tcgatgatcc cagctgaaac aagaatttcc aaacttagaa gtatatagcc tcccaacatc
   138421 tttttaatag cattgttctc gctgactcgg tcgctttgca cttttgtatg gacaaataaa
   138481 tatttcaaaa aatccttgat tgatagacaa acaccccaaa ccaataaaca gatagcaaag
   138541 atatcaagtc ccagtacaag tttttcgaaa tatggaagaa gaaactgcat caactctgtc
   138601 gtcatcctac ctctcctctt ctttgttttt ctttgtcttc tatttcctga ttcaagaaat
   138661 aagaaatgac tgttcgaatg ataataataa gtgcaagctt caaaatatct gtccaagtcg
   138721 gcttgataac tgactcgatg atatcagcaa cgactagtac ttccaagctt aacaaaatat
   138781 aacttgctag cagttttctt gtatctgcat tacgagtatt acgttctgca tagtttttct
   138841 tgacatgaga ccaatcaaaa agtttgaata gaacaagaac gatcccgaca attaagatac
   138901 cgatagaaca aatatttaaa atagcaatga tccattctag aaattcaatt aaatttgagc
   138961 gaaacatata cgctacctac tttcttttaa tttgttccta ttcttttatt gtaaaagaaa
   139021 gttaccttgt tcgtctattt aaaagttgtt ctaatgataa cggttcgctt aaatttttct
   139081 ttttcactct cccatttttc tccctccatc cataaatcgt ggaagtatcc aaaacaacgt
   139141 agcaagttaa aataaggctt agtccgtcat cagcttttca aagaagcact gtctcggtgc
   139201 tttttttgta cccaaatttc taaaaataga accatacacc tcctcaaatc ttttcttctt
   139261 acctacccta tttttattta caggaaaatc agacacttct tcttttttgt caaaatttcc
   139321 tttttcttct cgtcctatca tttggcattc taataaaaac gaactatcct tggatataga
   139381 aagagaaaac aaggaggcgt ttttcatgag taaaaaatta atcaaagtcg gcatcggttt
   139441 aggtttgctt gcccttggcg ctgcatatct aggaaaaaag acaggactat tcgaagatga
   139501 cagtcattta tatgatgaat tcgaatcaat ctagcatcct atttagttga atcactacgg
   139561 acatacttgg aagacattgg aggaatcaca atgagaaaaa gtaaagcaat aatgattggt
   139621 gccggtattg ccaatatggc agcggctgtt tatttgattc aagaaggcaa atggaaaggg
   139681 gatcagatca ccttttattc attggatgat cacggttcaa atgatggtgc accgaccgac
   139741 actgtagtgg atgaatattg gaataaaaac catccattag aaaaccaaaa aggctatatt
   139801 gctcgaggcg gtcgcatgct taattaccgt acctatgtag atttgatgga tctgttaagt
   139861 cgaatacctt ctgttactga gccagggatg actgctgaag aagatacgag agattttgat
   139921 gcaaaacacc gaacctttga caaagcacgt ttgatggaag gtggcaaagg aatcattgat
   139981 ggcggaaaac tgggattcaa taataaagac cgtattcttc tgactaaact gattgctatg
   140041 cctgattcag aagaagaaaa actagacaat atcactatcg aagaatattt caaagatgat
   140101 ccacactttt ttgaaacaaa cttctggttt atgtgggaaa caacatttgc tttcagaaca
   140161 cgtagttctg ctcaagaatt gcgtcgctat atgcatcaaa tgatttatga attcactcaa
   140221 atcgaacatc tagtgggcgt caatcgaaca cgttacaatc aatacgaaag tattatgctt
   140281 cctttgatcg agtacttgaa agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact
   140341 gactgggaat tcaaagaaac accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt
   140401 accaatacac tgactcaaga agaagaatac gttgtggtcg atgaagatac agcagttatt
   140461 ttcactaatg ggtccattac agattcagct actttaggag attacgaaac accagctgta
   140521 gaaaatatgg attatggtgc agcttctagt ctctggaaaa aagccagtga acgtttctac
   140581 aacttgggaa atcctgacaa attctttgct gatcgagatg caagcgaatg ggtcagcttt
   140641 accctgacga cgaaaaacca tttgttgttg aatgaaatca cccgtatcac gactcaagaa
   140701 ccaggaaatg ccttgaattc atttatttca accacaccga tcacgccgtt aggccaaaaa
   140761 gatgtcaata tgtctatcgt cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat
   140821 gaaacagtta tttggggtta tttcctttat ccaagacgac gtggcgaatt tgtggataaa
   140881 cagtatatta aaatgaatgg aaaagaaatg ctagaagaac tgattggaca actttcaaaa
   140941 gtagatcctg gaccagtgaa tattcgtgaa aaagaaacag aaattttcga cagcgtaata
   141001 aataatatcc ctgtctatat gccttatgct tccgcgttgt tcaataatcg tgccaaaagc
   141061 gatcgaccaa aagtcattcc taaacattcg accaatctgg cctttacagg agaatttgtc
   141121 gagcagcctt atcagatgat ctttactgaa caaagtgctg tacgttctgg agaaatcgct
   141181 gctttccatt ttgcgggtat tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa
   141241 gatattccta ctctagctcg tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa
   141301 aaagctgccc tgcatcaagt aataagaaca accaggctaa aacagcttct tatgtttttg
   141361 atttggttgg acttattacc gcagatgcaa gcttttgaac accgtttacc aagaggttgt
   141421 gaaaaagctg ccctgcatca agtaataaga acacccaagc taaaactgct tcttatgttt
   141481 ttgacttggt tggacttatt accgcagatg caagcttttg aacaccattt accaagaggt
   141541 tatgaaaaag ctgccctgca tcaagtaata agagcagcca agctaaaaca gcttcttatg
   141601 tttttgactt ggttagactt attaccgcag atgcaagctt ttgaacaccg tttaccaaga
   141661 ggttatgaaa aaggcgttta gtttcgagta tgaagaaaaa ttttgtgaaa atggttcctc
   141721 acgtttttgc ataaatttga cttaataccg agaaactgat cccttctgtc ataacctctt
   141781 tttatttatg tctgtttctt tttgaaaaca actatttttt caacgtttac tctcttgcca
   141841 atccaacatc atctaacgga tacaactatt tcaatgatta ccattacact aaaaaatcgg
   141901 aaacacacct ctccgaacac aaatacataa gactatagaa tgtttcattt aagaaaaaaa
   141961 gcgtttcatt atcaaaaagg taagatctcc tttaaaatga aattatctgt agtactaata
   142021 atgcagacaa ttttatgaat ctgaaaggag catctccaat gaaagcagtc acttggcaag
   142081 gaaaacagaa aatggaaatc agaaacgtag atgatccaaa aatattagaa ccaacagatg
   142141 caatcatccg tatcacagca acagccattt gcggctccga tctgcatctt taccatcatg
   142201 gtgaagcagt tttggaaaaa gggtatgttg taggacacga accaatggga atcgttgaag
   142261 aagtgggatc tcaagttcaa acattgaaaa aagggcaacg tgtggttatc ccttttaata
   142321 ttagttgtgg tcattgtcat ttctgcctga atcacatgga aagccaatgt gatgaatcaa
   142381 atccagatca gttatatggc gggcttttcg gatttggcaa gttgaacggt aatcattggg
   142441 gtggtcaagc ggaatatcta agagttcctt atgcagactc tacttcattt gttgtaccag
   142501 ataatgatct tcctgatgaa aaagttttat ttctatcaga tattttgccc acagcttatt
   142561 ggagcgttga aaacgcagga gtaaaaaaag gcgatacagt tgtgattcta ggttctggtc
   142621 cagtcggtct attcgctcaa aaattcgctg ttatggctgg agcagagcgc gtaatcgcag
   142681 tagatccagt acagcaccgt ctagataaag cggctaatta caatggggtt gaaacttatt
   142741 tcttagaaga cacggcacaa gctggaacag aattgtatga actggctaaa ggtggcgcag
   142801 atgtcattat cgattgtgta ggaatggacg gattagagcc tgtcaaagaa aaagcgaaaa
   142861 atttagtaag cttacaaagc ggcacaatct ctccattaca gatggcatcg caagctgtca
   142921 aaaaatttgg aacagtccaa gtaactggtg tttatatgac tccagcttct tcttacccgc
   142981 tgcaagaatt ttttatgcgg gatatcgctg tcaagcatgg acaggcacca attatccatc
   143041 taatgccaaa aatttacgca atgattgcag aaggactatt cgatcctaca caaatcatta
   143101 ctcattcgct gccactatca gaagcagcac aagcatatga gatctttgac aaaaaagaag
   143161 ataaaaatat aaaagttgtt ttgaaacctt gaattcagta aaaaatacag gtgattttct
   143221 ttatgcccaa aatcaaacga aatacccatg agatcgaaat aggaaaagaa gaagatatcg
   143281 aaatacgagg acgtcgcttc cgcttctatt tccaaaatcg ttacacattg atctcactgg
   143341 ctgtcgattt attaaccggg attttctata tttttggaag ccttgcttcc ttaactaaaa
   143401 tccccgatcg atatggcacc tatttttatt tggctggtgc tattttcttg acgattcgtc
   143461 ctattctcag aatcgtaagg aacattttta tttacgacga aaaaaaagca atgaagagaa
   143521 caagcaaaaa aaaagaggca tgagaatttt tcaaatctca tgcctctttt ttcaccctat
   143581 cgtatcactt tgatacagac gagcggtcgt cccactttct tccttgacca ttgtcaaaaa
   143641 tgtccactcg tatcgttcat aaaacgtggt atgatctgta attaagtaaa gtttttcgta
   143701 cccaagttga tgcatttctt ttctgatttc cgctaatatc cgcttggcta tcccctgctt
   143761 acgcttttcc ggttcaacaa acagggcaca aagatttggt gtcagatcag ggcggttatg
   143821 gaagtcgttt tcaatgacgc ccgctcctcc gacgatggtt tctttttcat ctaagaccac
   143881 ataccattga ggaatacttt ccttattagc gattccagta cgaatacttt cctcatacac
   143941 aacagcagga actccccatt ttgatgaaaa ccaattcgcg ctttgtttta ctaattctgg
   144001 gtgttctctt aatttgatcc agttatatgt aaccaatgtt taaacctccg actaaaataa
   144061 aacgtttaca aaaattatac aagtctttat gaaaattagc aatgacaaca atagtgatgt
   144121 aaaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt gattaatcaa gcatctaaag
   144181 cttcttttct tctttcttgg atcgtagcta ccttgacgaa cggtagatag atcaaaatag
   144241 aaagaaccaa attgacagcg gctagtacac cacctgcaat actttttgtt gccaatacac
   144301 cgccaataat tggtggagtt acccatggag gcataacggt agctgctggc actaaacctg
   144361 tagaagtcgc aaagtaagca acactaacta agaccattgg tgtcaaaata aatggaatga
   144421 acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta atattgaaga
   144481 cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta cgtcctacta
   144541 aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg acaaagctgt
   144601 caaagaaagg tttgttcacg ataaacggtg cgctatgccc agctgcgatt gcattaacgt
   144661 ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata ttcgctccgt
   144721 gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca gatggataag
   144781 agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct acgatatcat
   144841 caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata gtgatcattg
   144901 ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca ggcattttga
   144961 tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata atcccaacaa
   145021 taatagcaat aaacaaaccg tttgagctca tacctaatgc tccgcctaaa gcgaagaaag
   145081 agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgcta gctaaatgat
   145141 aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa tgtaccgttc caagcagcag
   145201 ccccgaatcc tttccatgat tcaccaccaa aaattgagtt catcaattct tggaacccgg
   145261 gaatcggtaa gttattgatc attactgcta atgctcctaa gatcattaac ggcatactca
   145321 ccataaatga gtcccgaatc gcaactaaat gccgttgtgc accaattttt gatgctacag
   145381 gtataaaatg tttctccata aatgcaacaa atttatccat aaatcttccc tcttttcttt
   145441 actgtagatt acgcgttcaa tcgacgatac agatcaatga tctcttttgc taaatctgta
   145501 aaagctatag atgtcatcag atgatcttga ctgtggaccg tcaaaagcgt gacttcaacg
   145561 tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag agtgatgtgc ttggactaaa
   145621 gattcctctg catctttgat tttttcatct gctaaagtga aatcaccttt tttcgcagca
   145681 gcaatcgctt ccattgcatc gctttttgca tttccgccaa acatgatcag acccatgatg
   145741 gcttctagat ttttttgatc ttccatttat tgtatcctcc gataattttt attatttgtt
   145801 tattagtttt tctgcttggt cgagtacttt ttcaccattc atcatgccat agtcagccat
   145861 attgattaca tctaaaggaa tgcctttagg tgctagcttt tcagcaaatt gattttgcat
   145921 aaagcgtact tgcggtccta aaagtaaaac gtctacattt ttagattcta gttgattatc
   145981 cgcatctgaa gcagatacag caaagatgtc tgcttccatt ccttttgctt ctgctgcctt
   146041 ttgcattttt gtgactagga gacttgtact cattccagct gaacatacaa gcatgattgt
   146101 tttcttttcc attttaaaca cgttcctttc tatacttaca cttgtatata agcaagtagc
   146161 gtgccaactt taaaagcgct ttaaaaagtt gatatcatca catttaaggt ctataccaag
   146221 ttgcatacac actaaaaaag aaagcgcaca ctaaacacac aaattaattt ttattacctt
   146281 ttttctttta acgtgcacaa aaaaagttgt gacacaaaac ttgtcacaac ttttttcaaa
   146341 taaacggtat tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacataag
   146401 atgttgtttt tactttgcta ttcttattac ttgatgcagg acagcttttt cacaacctct
   146461 caataaacgg tgttcaatca gctgaccctg ggtattagct caaaacgctg gattcacaac
   146521 ctcttttatt tcaaataacc agtaaataca atgaacatct acaaaaaact tctatttatt
   146581 tatagatttc gtcaggcaaa tccaattctc tcttatcaat caaagtctga taccacgaag
   146641 cagatttttt caatgttctg cttcgttcat cgttcaattc gattcgaact aatccatatc
   146701 gattcttaaa tgcattcatt ggtgacacac agtcagtgaa tgcccataac atatagcctt
   146761 cgcaatttgc gccttcttct gttgctttga tcaagtaatg caaatgctgt ccgataaatt
   146821 cgatacggta atcatcttgc acgattcctt tctcatccat atactgttct tcatattctc
   146881 ttcccatacc gttttctgtt atcagccaag ggatattatg ataattttct tttagataca
   146941 tggctatatc atacatgatt ttcggataga tttcccatcc cctggaatta ttcattttct
   147001 tcccaggtaa atcaaagact tcataatatc gttcaggatg gaaaggtgtc tcttcattcc
   147061 attgataacg aggggcgcga acgcgtttag gataatattg attgattcca aggaaatcta
   147121 ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg atcgaaataa atcgattgtt
   147181 tttgacacaa ctccaggaac tcttctgtgt agtatccttt taccatcgga tcaaaaaata
   147241 ctcgattata aaacaaatca tacatataag cagctttttg gtcttctgga gaattggatc
   147301 gagcatagac catttcagga tttaaaatac agccaatcct tccaccataa tttccgctgc
   147361 ggtaaatctc tactgcttta gccgttgcta aaactttatg ataattccac atcatccact
   147421 tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa atagcaacgc gtttggggaa
   147481 cgattggttc gttgaatgta aaccagtttt ttaccctatc accgtaacga tcaaaggcaa
   147541 tttgagcata cttagcataa aaatcaacta cttttcttga agaccagcca tcatattttt
   147601 ccaaaagaaa agctgggact tcataatgtt ccaaacaaat catcggttct acgtctgctt
   147661 cgatcaaaga gtcgatcatt tcacttatat gctgagcata ttcttcatct actatacagt
   147721 tctcataatc agtaaaaaaa cgagcccaat tgatagaagt ccgataatgt gtcagatgga
   147781 tggatttcat cagatccaca tcctgctggt attgttccat aaaattagtt gctacggctg
   147841 ggccataccc attatgccaa acaaaatgtt catttttata ccagctatct ataaacgaat
   147901 cctgtccttc tttttttcct ttccaacctt ccgtttgcca agcagaagat gcagcaccaa
   147961 gaataaaatt ttttggaata gtaattttca tgatttcctc ctgtttttta gatcccatca
   148021 ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga aacaataata
   148081 caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata agcattgacg
   148141 atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaatcc taaagcggtt
   148201 gcaaaataac caatcgttcc agtgataaga ggcgttaaga taaacggaat agctaaaatt
   148261 ggattcagca tgatcggcat accaaaaata actggttcat tgatgttgaa gatcccagga
   148321 gcaagggata acttggtgat ttgtttcata tcttcccgtt ttccaactaa caatactgca
   148381 atcagtaaac cgatcgtgac tccagacccg cccatactca tatacatatc ccaaaatggc
   148441 atagtaataa tgttcggtac ttcttttcca gcttcaaaag cttccgtatt tacagcaatt
   148501 gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg gataccaatc
   148561 acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc ttgtacgaca
   148621 ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat tcctgtaagt
   148681 tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt cgggaataaa
   148741 gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag ctgtagtttc
   148801 ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa cattcccaaa
   148861 aataaccctt tcgtatctgt atattgttta gccaatacgt tttctactat aacagtctga
   148921 ttttcattca ctaattcata aacagttgga ttaacagata aataagacat cactgcgatg
   148981 ataccaggga atacaccatc cactttattc agcttggcta attcgatccc tatcagaaaa
   149041 acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc gataggcttt
   149101 aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc cattttccga gtcaaagacc
   149161 attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa tgcagcaaat
   149221 gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac gttccctaaa
   149281 acattggcta atttatccat aaaactcatt ccagatcccc tcattcctgc ttcttctcct
   149341 tgacgtcatc tctttttgtc tattagtcag cgcttacatt tcgatgaaca gaaactattt
   149401 actcctcttt tttaccaaat ataaaacaaa aattcatctg atgtatttat cataaaatac
   149461 atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat tctctccgat
   149521 ttattgccat atggacagtc attgcatcaa acgcagcaag tgcattccgc ctttcgatgg
   149581 cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg atatcataat
   149641 ttttattaaa caaagcaatt gattcattaa tgattgggat aatatgcagc aaggctacgt
   149701 ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca tgttcttgtg
   149761 tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg acgatttgat
   149821 tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa tatctcagtt
   149881 caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg agtgggtcat
   149941 tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact tcaaggatat
   150001 tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc tctaaataat
   150061 cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt tcctttaaat
   150121 atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc aaaccacata
   150181 cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa tcatctgatg
   150241 attttttgta tacaaaattg attaatccgt tcatagacat acaaacgaag aagatattta
   150301 ccataaaaaa gactaggata aaattcactc ctagccttcg atcattttta ttttgaacga
   150361 caaaaaatat gatgttcaat aacagacgat cttcattcga ttcttgatgt catcttttgt
   150421 tttttttaat atatggataa aaagtttgat tacatcgttt ctattctaga atttggtcga
   150481 ttctcaattc ttcttctggt gagaaatcta aattatccat cattcgaaca ctttcttgta
   150541 actgacttaa ccgacttgct ccgaccagta cacttgtaac agatttttgt cgcaaattcc
   150601 atgcaagggc catttgcgct aatgattgtc ctcgtgatac ggcgattgtt tgcagtgctt
   150661 tgattttttc cagagttgat ccaacttgtt cttctgaaag gaatggtatt tccttacgat
   150721 gtgctctaga atcttcagga ataccatgta gataacgatt tgtcagcaac ccttgagcaa
   150781 gcggactgaa cgtgattgcc cctagccctt cttcttctaa tactggagat agatcgtctt
   150841 ctagtagtgc acgagaaaac atattgtagc gcatctgatg aataatgaac ggtgcttcct
   150901 ttctttttaa aatttcagtc atttttttgt atcttctcca ttatagttgg atataccaat
   150961 atataatgct tttccttgtc ttacaagttg catcaacgct tctgctgttt cttccaaagg
   151021 tgtatcaggg tctgggcgat gatgatagaa gatgtcaaca taatctagcc ccattctttg
   151081 gaaactttgg tcacaacttg atatgatgga tttacgagag ccccattccc catatggccc
   151141 ttcccacata tgataacctg ctttgctaga aataatcagt tcatcacggt aggcttgaaa
   151201 atcttctcta aaaatacgcc caaagttttt ctctgcagct ccagcagggc ctccataatt
   151261 attcgcaagg tcgaaatggg taattcccat gtcgaatgcg cctcttaaaa tctctctttg
   151321 attatggata ggatcataat caccaaaatt ttgccataat ccgagaggag agataaaatc
   151381 ggtaatttta aacctgaatg accggattta cgatattcca ttttttcata acgtgcacta
   151441 tctgcaatat acaatttttc tcctcctcat caaatctttt taaaacgctt tcttgttttc
   151501 tatttttagt ttactacatt ttaaagaaaa ggagttaatc aaaatgattt tttcgtatat
   151561 ttttttgcca tttgtttttt actcgttgat agatcagaaa ttgattacgt gcttgctgga
   151621 tttttttata gcgtttcggt tgttttttgt aaaattgctg atgatagttt tctgctggcc
   151681 aaaacgtacc ggctggttcg atttttgtga cgattggttg gtggaaagtt cctgaactgt
   151741 ctagtttctg ttttgattgt tccgctaatt ctttttgtcg ttcgtcttga taaaaaatca
   151801 ctggacgata ttgcttccct ctatcttgaa attgtccaaa tgtatctgtg ggatcagtaa
   151861 tttgccaata gattgtcagc aactcgctat aacttatttc tcttgtgtca taaatgatct
   151921 ccacagcttc cacatgacct gtgtaaccac cacttacttg atcataattc ggtttttcaa
   151981 catgtccgcc cgtgtatcct gacaaaacag ataggatccc ttttttcgat tcaaacggct
   152041 cgaccataca ccagaaacat ccccctgcaa atactgcacg ttcttgatag tcagcatctt
   152101 gcatggcatg cttggaaaag tcatattttt gctccttatc aaatccttcc gtaatcaata
   152161 aataaaagtc cattacatca ggcgtcagat tcattcggat agctaatgga cgtagtgtta
   152221 cttctagttt tgataactgt tctttaacgg atatattttc tcttgtgtca ttctttgtct
   152281 gaatcaatac ttttcgttcc caatctcgtg tattcggatt caaaatcaga ttataaagtg
   152341 tttgaatgaa tatttgttcc tcatccatag attctcctcc tttccgaaga agacaagcta
   152401 gtgactttag ctgtaattta tcataaagtg aggaaataat cgattgaatc gtatttattc
   152461 aaagaagata agcagcttca gatgatataa gatgatcttt atcttaaaaa gcatactcta
   152521 tggtttggtt taactaaaaa acgacctctg aaaaaaggga tgttctccaa ttctcagaag
   152581 tcgagtaaag atgattcttt tttatgagcg ataataaact tcatccaaaa acagaccttg
   152641 tgcagggacg gtttctcctg catgttgccg cactttgctt tcaaatattt catcgattgt
   152701 ttctatcggc atggcacctg tgccgatttc tagtaatgtc cccatgataa tccgcaccat
   152761 tttatataag aatccgtctc cgacaaaagt aaaatgaagc atttctccct ttcgttcgat
   152821 agataattca tcaatcgtac gcactgtgga tttttttgat tttttcaatg cagaaaaacc
   152881 aatgaaatca tgtgtaccca ctaatttttc gcaagctgca ttcagcttgt ccatatccaa
   152941 ctcttgaggg aaataaaagc tgtggtttcg ctcaaatgct gaaggaatca cgttgttcca
   153001 aacataatag ctgtattttt tgcccaccgc attatatctt gaatggaagc gctcaggcat
   153061 ttcttcgatt cttttgatga caatatcccg cggaaggtaa cgattcataa agtcgatcat
   153121 ttctgccagt ccaatttctg tgtttgtttt aaaatttgct acttgtcctc gcgcatgggt
   153181 gccagcatct gttcttcctg atccaataat ttctatctct tcatttgtca tctgatgcaa
   153241 tactttttcg atttttcctt gaatggtttt atcgtcatct ccaagtcttt gccatcctga
   153301 atatcttttt ccgtcatatt cgattgtcaa cttgatgttt ctcatatttt agtggctcct
   153361 ctgtcttcca tttggtcttc tctctacctt tttaagattg tagcacaaaa tatagctcct
   153421 tgcttctcta agacagaagc tatacaagaa aactgtggaa atatatattt cagaaaaaca
   153481 aaaaacagcc accggatgaa gtatccgctg actgttcaat ttgacggctc aagttttact
   153541 gtttgagatg caagatactc aaccaggcaa tgggcacata attaaagaaa aaactgattc
   153601 tttggcaaaa acctatttta ttcagtaatg gccaagaatt tatagaagga attcttgcca
   153661 gtccataaat cgccgcaaaa agcaaactga tcacagacag tccaaggtat aagtggctta
   153721 cgtccatttg cccatttttt cgatagatca agaaaagaag aactggaaac aataaaaaac
   153781 cactgtaacc taaacctgat ccgatattat ggacccatgt cgagacattc cacgaagatt
   153841 catgggtatt gatactgaac aaacctgtaa agatacaatc acctatacca tagaacgcga
   153901 tggctgctgt aactagggta gctaacacac gagatgtact tacaaatgca gcatacaatg
   153961 caggcaatga caggatgaaa aagatccctg aaaccacaga ccaaataaga aacgcttttc
   154021 ttacaggact ggaaacctct ccaaatacac tgatcacgct cttcatttga tctaattcag
   154081 gataatacaa tcctaatacg tacggagtca aaaaatcact cagcacgcct aataataaaa
   154141 agaaaaaacc aaatttacgt aaaaaatcca tgatacgcct ccaataacaa ttacctatgc
   154201 ttttaattgt tattataaac gactttatct tgatttaaca gaaacctcta tttacacgaa
   154261 catctatata actcattaaa aactcgaatc attttaaaaa tactaaatat ctaacgttca
   154321 acgttcactt aatccatcta aacaatcttt caatttgatt ttttccccac ttcttttacg
   154381 cgcgcctagc tctcctattg cagtaaacaa cagatcactt gacgaattta aggcagtttc
   154441 cattgaatcc tggataacac cgataataaa tccaatacca acgatttgca tcgcgacatc
   154501 attagagata ccaaacaaac tacatgctaa tggaatcaat aacagtgaac cgcccgcaac
   154561 acctgaagct ccacaagcag ctaaagcaga caaaatacat aaaaggactt tcaaaacaaa
   154621 tggtgcttca atccctaaag aatgtacagc agtcaacgtc atcaaggaaa tggtaatcgc
   154681 ggcaccgccc atattgatcg tagcacctaa cgggatcgat atggaataag actcttttgt
   154741 caatttcaat ctttcagcca acatcatgtt tatcgggata tttgcggcag aacttcgggt
   154801 aaagaaagcg ggaagtgcgc tttctttcaa acaaaagaaa atcaatggat agggattttc
   154861 tttaataaac aaaaacgtga ggaatgggta cacaactaat gcgacaaaca gcatcgtacc
   154921 gatcaaaaca agtaaaagct gcagatactc tgccaatcca gcgattccag tcgtagcaat
   154981 tgattgataa accaatccta aaatccctat cggagcaaat gcaataatca cttgtacgac
   155041 ttgtgacaac gctatagata tctgatccac caactctttt gtcggttctg aacgtgctcg
   155101 aaaagctagt cccaacaata cagcccagaa taaaacgcca aggtaattcg catcaataag
   155161 agattgaaca ggattttgtg tgacattcgt caacatagta gataaaacac tttccaaact
   155221 ttgcggtgct ttttcagata ctgtttcttg taaagtaata ggaacagtaa aaattgaact
   155281 tacaatgact gctacaagtg cagaaagcaa tgttcccact aaatataaga tcaaaatagg
   155341 cttcacgaat gtcttattcc caattttatg cttggcaatt gacgccatcg tcaagaaaaa
   155401 aaccagaata ggtgcgattg ccttcaagca actgacaaac aacgtcccca atattgaaat
   155461 aaatgtccac gtggggaaaa agataccaaa caatattccg actaaaatac caacaacaat
   155521 acgttgaact aacgacatat ccaaaaactt ctctaacaaa tgaccaccct ttcacaattt
   155581 taacaatcat tgtatcattt tatctaaaga aactaaaggt gcaattttct aaaaattcta
   155641 ataatacaat tggcaattca tgctcttgca acattcaatt ttagtattgg agggtttatt
   155701 caatctctaa agaagtcgag agaaaactat ttatcgttat tattatagtt atccaagtaa
   155761 aacgtaacta agatgaagga cgaaactaga aatttcatcc ttcatcttaa ttcttagaca
   155821 tagcaatcaa ttaatatttt ccactgagtc tcttctttct ctcactctca ctggtttact
   155881 tacccataaa cgatttgatt aaagccattt ttcaattcat tattcgctgt ctcgttaaag
   155941 taaagataat tatcgggatt cccctgattt tgttgtgtca ccaatacttt tggctgattt
   156001 tgctgaaacc cgaatagata gacgtgcttt ttcagatatg gttctgtctc tgcatcggaa
   156061 tagacggctg tgatttgata gtctgcttga cctgtcccac tttctgacca ttctgcagaa
   156121 acaggcactc caccaatagc catcttccac tccccgttca aaataacttg agggacttta
   156181 agaccatata agtccacact catttgattc gtatagcttt tgtattgttg tcccattgtt
   156241 tggccccatg tagccataaa tgcctctaat tgtgcggatt tgtctgcatt ccacagtgtt
   156301 tgttcgactt gttcgctgct ttctgaagat gaagcctcta cagaagaact tgaagtagat
   156361 gtttgagttg tttcagtcgt tttggaagac tctgacgaag tagaggtatc tgctgtttcc
   156421 gtacttgctg cagttggctt gctctctgtg ctagttgttg tagtagttgc aattgttgct
   156481 ttcgctgttt cttttgttga ttcttttttc gattcattcc cgttggtaca accagctaac
   156541 aaaaaagcta gaccaattgt tactaaaatc ctttttttaa attaaaaaac tcctttcgat
   156601 tactcccact tctttattct atcaaataag caatgtgatt ttattgattt tttgtatttt
   156661 ctcatccatc ttttaaacct tttaaaaact aagaagcacc cgctgatgtt gtctgtaata
   156721 catcagcggg tgcttctttt attttaatct tcgcgatttt ccaatttacc tcacgcttta
   156781 tatttgtatt tgaagaaaca tagactttta gtcatcatcg tcttcctcat ccaaatcttg
   156841 tcggacagtt tttccttgga gtctttgtac ttggtagatg atttctttat tgaaacttaa
   156901 aagttcaaca agcaattgtt tcaagccata tttttcttct ttttcagcta atttgattgc
   156961 ccgtgtgata aagacatttt ggaaatcaaa atcttttgca aagttttcca acattgttga
   157021 ggctggtaaa tatttgtttt gaccatgttc gtaaattttt ccataacgca tgacttcttc
   157081 taaagtagac ggaacgattt cattttcaat cactaactca tgagagattt tattgaacca
   157141 tctcgcttct tgatcagcat attctgaaaa aagggtactt aattcttgcg aagatgtacc
   157201 caaaacatac aattgtgctt ggatcaattt catttcttct aatttaaaat ttgccaatac
   157261 atgccccacc atggcgccag cagttggttt atgatgatcg atatctgctt gttttgtttc
   157321 ttgagcaaat ttttcttcca ctatattcac tgatttacgc ctcttttact tttgttgatt
   157381 ggacttcata acctaatttt tccacaactg cagctaattg ttcagggtgg acttcatctg
   157441 gatcaaagtt tgctttgatt ttgctcgcat taaacaaaac tttcgtattg cttaccccag
   157501 gctgttgaga aaccgcatgt tctatttttt gcatacagct tggacaagct agtgtatcta
   157561 attgcataat catttttttc atcgtagttc ttccttcctt tttcttgata gtcttattct
   157621 agattacagc ttccataaaa aaattgattc ttatcaagtt ttacgatttt tcttctttgc
   157681 tttcgtgtcc aaaatacaat aaacgcatcg cgttaaagat aacgatcaag atactagctt
   157741 cgtgaacgaa catcccacta gccatgtaaa taaacccggc aaataagccg atgagtaaaa
   157801 ataagacgac accaatggca atcactacat tttcacgggt attcaaaaca gttttcttag
   157861 ccaaacggta agcatgaacc aacgatccaa aactagattg catcaagaca acgtcactcg
   157921 tttcgatagc gacatccgtt cctgatccca tagcaatccc gatatcagcc gcagccaaag
   157981 agggagaatc attgattcca tctccaatga aagcaacgtg caatccttgt tcttggtatt
   158041 ttttcacaaa ttgaaccttt tcatctggca ataattcagc atggacttca tcaatgccta
   158101 acatgtcagc tacataatca gcagtcatct gattatcacc tgtcagcatc actaaatgtt
   158161 ttgctcctgc ttgtttcaac atagctaatt gttcagcgac ttctggtcga atcacatctg
   158221 acacaccaat gatttgagtg atttttttgt cgattgctac aataatgact gagctgcctc
   158281 tttgttgtaa ttgatgtaaa tcttgtactt gctttggtgt gagagaaagt ttgtgagcgg
   158341 caatcaattt ggtgttgccc gcacaaactg tatgaccatc aatctcagct gtgattcctt
   158401 gtcccttgat cgtctgatta tctttgactg ctaattgttg aaaatcaatg tctttctcct
   158461 gagcataatg gatcacggcg cgccccagag gatgatcgga taacgtttct aatcgagcca
   158521 ctaaagctaa gctgtcccct tcatcctctg tatagttctt gatagtggat acagcagtag
   158581 ttcctttggt caatgtaccg gttttatcaa agacaaaagt atcgattttg gaaaaagtat
   158641 ccattgcttc accgcctttg actaagatgc cccgtttcgc tccattaccg attcctgcta
   158701 cattcgaaac aggcgcacca atgactaaag cgccaggaca accaagaacc aaaacagtga
   158761 tggctaaacg aaaatcacga ctgatcagac caacaagcaa cgcaataagt aaaacggttg
   158821 gagtataata ctgagaaaat tgatcaatga atttttccgc atgtgatttg gtatcttgtg
   158881 cttcttcgac taattctata attttggcaa aggtcgtatc atctccgacc ttagttgctt
   158941 cgatcgtcac gtagccatct gctaaaatcg ttccagaaaa tacgttatct ccactgattt
   159001 tgacgacttg tcgtgattca cccgtcactg cggcttcatc cgcataccct ttcccgtcaa
   159061 tgactcgtcc gtccacagga atagctccac cagtttttac taagacgata tcgccttctt
   159121 ccacgtcatc gatttccact tcttcggtcg ttccatcttc ttggacaacg ctggcagtcg
   159181 atggggccat ctcggtcaaa gccttgattg attcccgcgt tttggtcaat gttttttgtt
   159241 ccagataact accaaacaaa aacaagaatg taacgatagc tgactccttg tattctccga
   159301 tcataaaggc accaagcaca gcaatagtaa cgagtaaatc aattgagata actttgactt
   159361 ttactgcctg atacgcatgg attataatag gtatgaccgc aataatagaa gctatggcta
   159421 gagcaatgtt atagaacaag acaaatccag taaatttccc gataaaacca aaaataatca
   159481 acacagctga taaggcggtg atatgatttc gatgctcttg gatccacttt tgtaatttca
   159541 tctttctccc tcttttcctt ttcattctta cgagactaag tatagatact tatccatcat
   159601 aaaaaattga ccactatcaa gtttattcaa aaaggcggtt ttcttttggt atactgaatt
   159661 cctacagtca ttaaacgatc atatagaaaa aggaagcgcc gaaacgcttc cttaggtagt
   159721 tctatttttt tattcaaaga taagatgctt tgtcatctta cgactgaaga acaacaatca
   159781 aaaaagggca gcagccactc attcacaaga aatatcgttt tttgatatgg gagttgaagc
   159841 agtggacaaa tatctctact tattagctgg gaataagatc caaaaaagct taatggattt
   159901 tatccaagaa ttggaatgta ctttccacaa aaaattcact cattccattc ttttaaaact
   159961 tttgattcat acagcgtgtc taattgagcg tacattgata aacggtcatg aacttaaaat
   160021 tatatcagaa gatgacacaa gaccttctca tgaaacaatt tttcatgtaa aaaaggcctt
   160081 caaaaatatt gaaacagaat ttgggatcac tgtttcttat gatgaatgtt tctttatcta
   160141 tgatattatc gcatctaaat aatctttttt tatgtaaacg agtattttgg gagcgtcaat
   160201 aattttgtgt aaataaattg tcctcctgca aaataattag ttactcagta aacattgaaa
   160261 ctaatgtatc ggttac
//
LOCUS       DBGZHO010000002       136635 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.002, whole genome shotgun sequence.
ACCESSION   DBGZHO010000002 DBGZHO010000000
VERSION     DBGZHO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 136635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 136635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..136635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.002"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="ACN3HL_000144"
     CDS             212..604
                     /locus_tag="ACN3HL_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHC8005058.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACN3HL_000145"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACN3HL_000145"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HHC8005059.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACN3HL_000146"
     CDS             2698..2943
                     /locus_tag="ACN3HL_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005060.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3164..4774
                     /locus_tag="ACN3HL_000147"
     CDS             3164..4774
                     /locus_tag="ACN3HL_000147"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HHC8005061.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4751..4963)
                     /locus_tag="ACN3HL_000148"
     CDS             complement(4751..4963)
                     /locus_tag="ACN3HL_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005062.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKLEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5066..5935
                     /locus_tag="ACN3HL_000149"
     CDS             5066..5935
                     /locus_tag="ACN3HL_000149"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HHC8005063.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="ACN3HL_000150"
     CDS             6100..7371
                     /locus_tag="ACN3HL_000150"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HHC8005064.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="ACN3HL_000151"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="ACN3HL_000151"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HHC8005065.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="ACN3HL_000152"
     CDS             8762..9025
                     /locus_tag="ACN3HL_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HHC8005066.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="ACN3HL_000153"
     CDS             9470..9919
                     /locus_tag="ACN3HL_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8005067.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="ACN3HL_000154"
     CDS             9976..11394
                     /locus_tag="ACN3HL_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HHC8005068.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="ACN3HL_000155"
     CDS             11394..12254
                     /locus_tag="ACN3HL_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HHC8005069.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="ACN3HL_000156"
     CDS             12428..13201
                     /locus_tag="ACN3HL_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8005070.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="ACN3HL_000157"
     CDS             13348..13713
                     /locus_tag="ACN3HL_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HHC8005071.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="ACN3HL_000158"
     CDS             complement(13861..15069)
                     /locus_tag="ACN3HL_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8005072.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVFALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="ACN3HL_000159"
     CDS             complement(15088..15366)
                     /locus_tag="ACN3HL_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005073.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15559..16215
                     /locus_tag="ACN3HL_000160"
     CDS             15559..16215
                     /locus_tag="ACN3HL_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHC8005074.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16657..17454)
                     /locus_tag="ACN3HL_000161"
     CDS             complement(16657..17454)
                     /locus_tag="ACN3HL_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HHC8005075.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="ACN3HL_000162"
     CDS             complement(17451..18635)
                     /locus_tag="ACN3HL_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HHC8005076.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="ACN3HL_000163"
     CDS             complement(18660..19907)
                     /locus_tag="ACN3HL_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HHC8005077.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="ACN3HL_000164"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="ACN3HL_000164"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HHC8005078.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="ACN3HL_000165"
     CDS             21887..22201
                     /locus_tag="ACN3HL_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HHC8005079.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="ACN3HL_000166"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="ACN3HL_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HHC8005080.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /gene="tmk"
                     /locus_tag="ACN3HL_000167"
     CDS             22886..23530
                     /gene="tmk"
                     /locus_tag="ACN3HL_000167"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HHC8005081.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="ACN3HL_000168"
     CDS             23545..23874
                     /locus_tag="ACN3HL_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HHC8005082.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="ACN3HL_000169"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="ACN3HL_000169"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HHC8005083.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="ACN3HL_000170"
     CDS             24862..25686
                     /locus_tag="ACN3HL_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HHC8005084.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="ACN3HL_000171"
     CDS             25679..26026
                     /locus_tag="ACN3HL_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HHC8005085.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="ACN3HL_000172"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="ACN3HL_000172"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HHC8005086.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="ACN3HL_000173"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="ACN3HL_000173"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HHC8005087.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACN3HL_000174"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACN3HL_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HHC8005088.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACN3HL_000175"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACN3HL_000175"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HHC8005089.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31683..32450
                     /locus_tag="ACN3HL_000176"
     CDS             31683..32450
                     /locus_tag="ACN3HL_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005090.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="ACN3HL_000177"
     CDS             32440..34482
                     /locus_tag="ACN3HL_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005091.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="ACN3HL_000178"
     CDS             34763..34912
                     /locus_tag="ACN3HL_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HHC8005092.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="ACN3HL_000179"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="ACN3HL_000179"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HHC8005093.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="ACN3HL_000180"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="ACN3HL_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HHC8005094.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="ACN3HL_000181"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="ACN3HL_000181"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HHC8005095.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="ACN3HL_000182"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="ACN3HL_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HHC8005096.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="ACN3HL_000183"
     CDS             39329..40411
                     /locus_tag="ACN3HL_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HHC8005097.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40411..41214
                     /locus_tag="ACN3HL_000184"
     CDS             40411..41214
                     /locus_tag="ACN3HL_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HHC8005098.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41284..42024
                     /locus_tag="ACN3HL_000185"
     CDS             41284..42024
                     /locus_tag="ACN3HL_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHC8005099.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42035..43039
                     /locus_tag="ACN3HL_000186"
     CDS             42035..43039
                     /locus_tag="ACN3HL_000186"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HHC8005100.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43084..44928)
                     /locus_tag="ACN3HL_000187"
     CDS             complement(43084..44928)
                     /locus_tag="ACN3HL_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005101.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="ACN3HL_000188"
     CDS             45140..45658
                     /locus_tag="ACN3HL_000188"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHC8005102.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="ACN3HL_000189"
     CDS             45786..46469
                     /locus_tag="ACN3HL_000189"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HHC8005103.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="ACN3HL_000190"
     tRNA            46778..46851
                     /locus_tag="ACN3HL_000190"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="ACN3HL_000191"
     CDS             47010..47369
                     /locus_tag="ACN3HL_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HHC8005104.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="ACN3HL_000192"
     CDS             47492..49123
                     /locus_tag="ACN3HL_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HHC8005105.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="ACN3HL_000193"
     CDS             complement(49185..49826)
                     /locus_tag="ACN3HL_000193"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HHC8005106.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50012..50088
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="ACN3HL_000194"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="ACN3HL_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HHC8005107.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="ACN3HL_000195"
     CDS             50443..50787
                     /locus_tag="ACN3HL_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HHC8005108.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="ACN3HL_000196"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="ACN3HL_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HHC8005109.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51527..54334
                     /locus_tag="ACN3HL_000197"
     CDS             51527..54334
                     /locus_tag="ACN3HL_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8005110.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="ACN3HL_000198"
     CDS             54525..55016
                     /locus_tag="ACN3HL_000198"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HHC8005111.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /locus_tag="ACN3HL_000199"
     CDS             55119..56108
                     /locus_tag="ACN3HL_000199"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HHC8005112.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="ACN3HL_000200"
     CDS             56141..56944
                     /locus_tag="ACN3HL_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HHC8005113.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="ACN3HL_000201"
     CDS             56965..57879
                     /locus_tag="ACN3HL_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8005114.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="ACN3HL_000202"
     CDS             57962..58336
                     /locus_tag="ACN3HL_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HHC8005115.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="ACN3HL_000203"
     CDS             58475..58720
                     /locus_tag="ACN3HL_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHC8005116.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="ACN3HL_000204"
     CDS             58892..59956
                     /locus_tag="ACN3HL_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HHC8005117.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="ACN3HL_000205"
     CDS             60202..60627
                     /locus_tag="ACN3HL_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHC8005118.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="ACN3HL_000206"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="ACN3HL_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HHC8005119.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="ACN3HL_000207"
     CDS             61166..62020
                     /locus_tag="ACN3HL_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HHC8005120.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /gene="xseA"
                     /locus_tag="ACN3HL_000208"
     CDS             62021..63358
                     /gene="xseA"
                     /locus_tag="ACN3HL_000208"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HHC8005121.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="ACN3HL_000209"
     CDS             63363..63587
                     /locus_tag="ACN3HL_000209"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HHC8005122.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="ACN3HL_000210"
     CDS             63589..64479
                     /locus_tag="ACN3HL_000210"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HHC8005123.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="ACN3HL_000211"
     CDS             64488..65306
                     /locus_tag="ACN3HL_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HHC8005124.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="ACN3HL_000212"
     CDS             65413..65862
                     /locus_tag="ACN3HL_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHC8005125.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="ACN3HL_000213"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="ACN3HL_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HHC8005126.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="ACN3HL_000214"
     CDS             complement(67617..67733)
                     /locus_tag="ACN3HL_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HHC8005127.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="ACN3HL_000215"
     CDS             complement(67806..68762)
                     /locus_tag="ACN3HL_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHC8005128.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="ACN3HL_000216"
     CDS             68933..69301
                     /locus_tag="ACN3HL_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HHC8005129.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="ACN3HL_000217"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="ACN3HL_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HHC8005130.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="ACN3HL_000218"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="ACN3HL_000218"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HHC8005131.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71294
                     /gene="ftsL"
                     /locus_tag="ACN3HL_000219"
     CDS             70887..71294
                     /gene="ftsL"
                     /locus_tag="ACN3HL_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HHC8005132.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRIRKVK"
     gene            71295..73487
                     /locus_tag="ACN3HL_000220"
     CDS             71295..73487
                     /locus_tag="ACN3HL_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HHC8005133.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73513..74475
                     /gene="mraY"
                     /locus_tag="ACN3HL_000221"
     CDS             73513..74475
                     /gene="mraY"
                     /locus_tag="ACN3HL_000221"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HHC8005134.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74489..75850
                     /gene="murD"
                     /locus_tag="ACN3HL_000222"
     CDS             74489..75850
                     /gene="murD"
                     /locus_tag="ACN3HL_000222"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HHC8005135.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75876..76964
                     /gene="murG"
                     /locus_tag="ACN3HL_000223"
     CDS             75876..76964
                     /gene="murG"
                     /locus_tag="ACN3HL_000223"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HHC8005136.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76979..78199
                     /locus_tag="ACN3HL_000224"
     CDS             76979..78199
                     /locus_tag="ACN3HL_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HHC8005137.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78355..79680
                     /gene="ftsA"
                     /locus_tag="ACN3HL_000225"
     CDS             78355..79680
                     /gene="ftsA"
                     /locus_tag="ACN3HL_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HHC8005138.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79703..80944
                     /gene="ftsZ"
                     /locus_tag="ACN3HL_000226"
     CDS             79703..80944
                     /gene="ftsZ"
                     /locus_tag="ACN3HL_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HHC8005139.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80961..81638
                     /locus_tag="ACN3HL_000227"
     CDS             80961..81638
                     /locus_tag="ACN3HL_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HHC8005140.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81652..82251
                     /locus_tag="ACN3HL_000228"
     CDS             81652..82251
                     /locus_tag="ACN3HL_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HHC8005141.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82332..82553
                     /locus_tag="ACN3HL_000229"
     CDS             82332..82553
                     /locus_tag="ACN3HL_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HHC8005142.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82602..83384
                     /locus_tag="ACN3HL_000230"
     CDS             82602..83384
                     /locus_tag="ACN3HL_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HHC8005143.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83405..84112
                     /locus_tag="ACN3HL_000231"
     CDS             83405..84112
                     /locus_tag="ACN3HL_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HHC8005144.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84374..87172
                     /gene="ileS"
                     /locus_tag="ACN3HL_000232"
     CDS             84374..87172
                     /gene="ileS"
                     /locus_tag="ACN3HL_000232"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HHC8005145.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87221..88747)
                     /gene="zwf"
                     /locus_tag="ACN3HL_000233"
     CDS             complement(87221..88747)
                     /gene="zwf"
                     /locus_tag="ACN3HL_000233"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HHC8005146.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88762..89409)
                     /locus_tag="ACN3HL_000234"
     CDS             complement(88762..89409)
                     /locus_tag="ACN3HL_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HHC8005147.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89593..89922)
                     /locus_tag="ACN3HL_000235"
     CDS             complement(89593..89922)
                     /locus_tag="ACN3HL_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HHC8005148.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90099..90827
                     /gene="sfsA"
                     /locus_tag="ACN3HL_000236"
     CDS             90099..90827
                     /gene="sfsA"
                     /locus_tag="ACN3HL_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HHC8005149.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90843..91856
                     /locus_tag="ACN3HL_000237"
     CDS             90843..91856
                     /locus_tag="ACN3HL_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8005150.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91856..93133
                     /locus_tag="ACN3HL_000238"
     CDS             91856..93133
                     /locus_tag="ACN3HL_000238"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHC8005151.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93196..95898
                     /locus_tag="ACN3HL_000239"
     CDS             93196..95898
                     /locus_tag="ACN3HL_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8005152.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96050..96367
                     /locus_tag="ACN3HL_000240"
     CDS             96050..96367
                     /locus_tag="ACN3HL_000240"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8005153.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96397..96717
                     /locus_tag="ACN3HL_000241"
     CDS             96397..96717
                     /locus_tag="ACN3HL_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHC8005154.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96825..98285
                     /locus_tag="ACN3HL_000242"
     CDS             96825..98285
                     /locus_tag="ACN3HL_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHC8005155.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98353..98574
                     /locus_tag="ACN3HL_000243"
     CDS             98353..98574
                     /locus_tag="ACN3HL_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005156.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98605..98787
                     /locus_tag="ACN3HL_000244"
     CDS             98605..98787
                     /locus_tag="ACN3HL_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HHC8005157.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98787..99200
                     /locus_tag="ACN3HL_000245"
     CDS             98787..99200
                     /locus_tag="ACN3HL_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HHC8005158.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99323..100504
                     /locus_tag="ACN3HL_000246"
     CDS             99323..100504
                     /locus_tag="ACN3HL_000246"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005159.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100575..100739)
                     /locus_tag="ACN3HL_000247"
     CDS             complement(100575..100739)
                     /locus_tag="ACN3HL_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005160.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100893..100966
                     /locus_tag="ACN3HL_000248"
     tRNA            100893..100966
                     /locus_tag="ACN3HL_000248"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100927..100929,aa:Arg,seq:cct)
     gene            complement(101035..102174)
                     /locus_tag="ACN3HL_000249"
     CDS             complement(101035..102174)
                     /locus_tag="ACN3HL_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005161.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            102346..102480
                     /locus_tag="ACN3HL_000250"
     CDS             102346..102480
                     /locus_tag="ACN3HL_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005162.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(102473..103108)
                     /locus_tag="ACN3HL_000251"
     CDS             complement(102473..103108)
                     /locus_tag="ACN3HL_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005163.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103221..103856)
                     /locus_tag="ACN3HL_000252"
     CDS             complement(103221..103856)
                     /locus_tag="ACN3HL_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HHC8005164.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103890..104351)
                     /locus_tag="ACN3HL_000253"
     CDS             complement(103890..104351)
                     /locus_tag="ACN3HL_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HHC8005165.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104481..104912)
                     /locus_tag="ACN3HL_000254"
     CDS             complement(104481..104912)
                     /locus_tag="ACN3HL_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HHC8005166.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104930..105250)
                     /locus_tag="ACN3HL_000255"
     CDS             complement(104930..105250)
                     /locus_tag="ACN3HL_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005167.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105549..106325
                     /locus_tag="ACN3HL_000256"
     CDS             105549..106325
                     /locus_tag="ACN3HL_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HHC8005168.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106340..106543
                     /locus_tag="ACN3HL_000257"
     CDS             106340..106543
                     /locus_tag="ACN3HL_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005169.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106559..106897
                     /locus_tag="ACN3HL_000258"
     CDS             106559..106897
                     /locus_tag="ACN3HL_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HHC8005170.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            106884..107063
                     /locus_tag="ACN3HL_000259"
     CDS             106884..107063
                     /locus_tag="ACN3HL_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005171.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(107106..107576)
                     /locus_tag="ACN3HL_000260"
     CDS             complement(107106..107576)
                     /locus_tag="ACN3HL_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005172.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            107663..108361
                     /locus_tag="ACN3HL_000261"
     CDS             107663..108361
                     /locus_tag="ACN3HL_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HHC8005173.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            108539..108880
                     /locus_tag="ACN3HL_000262"
     CDS             108539..108880
                     /locus_tag="ACN3HL_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005174.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            108873..109544
                     /locus_tag="ACN3HL_000263"
     CDS             108873..109544
                     /locus_tag="ACN3HL_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HHC8005175.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109550..110236
                     /locus_tag="ACN3HL_000264"
     CDS             109550..110236
                     /locus_tag="ACN3HL_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HHC8005176.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            110239..110988
                     /locus_tag="ACN3HL_000265"
     CDS             110239..110988
                     /locus_tag="ACN3HL_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005177.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            111000..111269
                     /locus_tag="ACN3HL_000266"
     CDS             111000..111269
                     /locus_tag="ACN3HL_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005178.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            111274..111438
                     /locus_tag="ACN3HL_000267"
     CDS             111274..111438
                     /locus_tag="ACN3HL_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005179.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            111431..111733
                     /locus_tag="ACN3HL_000268"
     CDS             111431..111733
                     /locus_tag="ACN3HL_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005180.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            111730..111891
                     /locus_tag="ACN3HL_000269"
     CDS             111730..111891
                     /locus_tag="ACN3HL_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HHC8005181.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            111888..112193
                     /locus_tag="ACN3HL_000270"
     CDS             111888..112193
                     /locus_tag="ACN3HL_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005182.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            112193..112549
                     /locus_tag="ACN3HL_000271"
     CDS             112193..112549
                     /locus_tag="ACN3HL_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HHC8005183.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            112509..112754
                     /locus_tag="ACN3HL_000272"
     CDS             112509..112754
                     /locus_tag="ACN3HL_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005184.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            112751..113170
                     /locus_tag="ACN3HL_000273"
     CDS             112751..113170
                     /locus_tag="ACN3HL_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HHC8005185.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            113167..113724
                     /locus_tag="ACN3HL_000274"
     CDS             113167..113724
                     /locus_tag="ACN3HL_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HHC8005186.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            113721..114017
                     /locus_tag="ACN3HL_000275"
     CDS             113721..114017
                     /locus_tag="ACN3HL_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005187.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            114094..114507
                     /locus_tag="ACN3HL_000276"
     CDS             114094..114507
                     /locus_tag="ACN3HL_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HHC8005188.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            114816..114968
                     /locus_tag="ACN3HL_000277"
     CDS             114816..114968
                     /locus_tag="ACN3HL_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005189.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(114965..115240)
                     /locus_tag="ACN3HL_000278"
     CDS             complement(114965..115240)
                     /locus_tag="ACN3HL_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005190.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            115736..115900
                     /locus_tag="ACN3HL_000279"
     CDS             115736..115900
                     /locus_tag="ACN3HL_000279"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005191.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            116096..116263
                     /locus_tag="ACN3HL_000280"
     CDS             116096..116263
                     /locus_tag="ACN3HL_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HHC8005192.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            116289..116633
                     /locus_tag="ACN3HL_000281"
     CDS             116289..116633
                     /locus_tag="ACN3HL_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HHC8005193.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            116638..116919
                     /locus_tag="ACN3HL_000282"
     CDS             116638..116919
                     /locus_tag="ACN3HL_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005194.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            117022..117336
                     /locus_tag="ACN3HL_000283"
     CDS             117022..117336
                     /locus_tag="ACN3HL_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HHC8005195.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            117314..119008
                     /locus_tag="ACN3HL_000284"
     CDS             117314..119008
                     /locus_tag="ACN3HL_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HHC8005196.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            119028..120206
                     /locus_tag="ACN3HL_000285"
     CDS             119028..120206
                     /locus_tag="ACN3HL_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHC8005197.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            120169..120855
                     /locus_tag="ACN3HL_000286"
     CDS             120169..120855
                     /locus_tag="ACN3HL_000286"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HHC8005198.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            120855..122015
                     /locus_tag="ACN3HL_000287"
     CDS             120855..122015
                     /locus_tag="ACN3HL_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HHC8005199.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            122025..122900
                     /locus_tag="ACN3HL_000288"
     CDS             122025..122900
                     /locus_tag="ACN3HL_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005200.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            122897..123208
                     /locus_tag="ACN3HL_000289"
     CDS             122897..123208
                     /locus_tag="ACN3HL_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005201.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            123198..123551
                     /locus_tag="ACN3HL_000290"
     CDS             123198..123551
                     /locus_tag="ACN3HL_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HHC8005202.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            123541..123942
                     /locus_tag="ACN3HL_000291"
     CDS             123541..123942
                     /locus_tag="ACN3HL_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005203.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            123935..124339
                     /locus_tag="ACN3HL_000292"
     CDS             123935..124339
                     /locus_tag="ACN3HL_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005204.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            124351..124959
                     /locus_tag="ACN3HL_000293"
     CDS             124351..124959
                     /locus_tag="ACN3HL_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHC8005205.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            124979..125341
                     /locus_tag="ACN3HL_000294"
     CDS             124979..125341
                     /locus_tag="ACN3HL_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005206.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            125344..125526
                     /locus_tag="ACN3HL_000295"
     CDS             125344..125526
                     /locus_tag="ACN3HL_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005207.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            125543..128974
                     /locus_tag="ACN3HL_000296"
     CDS             125543..128974
                     /locus_tag="ACN3HL_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HHC8005208.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            129025..129762
                     /locus_tag="ACN3HL_000297"
     CDS             129025..129762
                     /locus_tag="ACN3HL_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HHC8005209.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            129772..132063
                     /locus_tag="ACN3HL_000298"
     CDS             129772..132063
                     /locus_tag="ACN3HL_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HHC8005210.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            132087..134213
                     /locus_tag="ACN3HL_000299"
     CDS             132087..134213
                     /locus_tag="ACN3HL_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005211.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            134230..134379
                     /locus_tag="ACN3HL_000300"
     CDS             134230..134379
                     /locus_tag="ACN3HL_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005212.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            134376..134822
                     /locus_tag="ACN3HL_000301"
     CDS             134376..134822
                     /locus_tag="ACN3HL_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005213.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            134824..134961
                     /locus_tag="ACN3HL_000302"
     CDS             134824..134961
                     /locus_tag="ACN3HL_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HHC8005214.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            134999..135292
                     /locus_tag="ACN3HL_000303"
     CDS             134999..135292
                     /locus_tag="ACN3HL_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005215.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            135289..135513
                     /locus_tag="ACN3HL_000304"
     CDS             135289..135513
                     /locus_tag="ACN3HL_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HHC8005216.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            135510..136535
                     /locus_tag="ACN3HL_000305"
     CDS             135510..136535
                     /locus_tag="ACN3HL_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HHC8005217.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
BASE COUNT        45486 a        22768 c        28628 g        39753 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct aatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttgatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgatttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagta gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcaaatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaatacctat ttctgaatat
    40441 cggaaaaaag cacgagtttc tttggaaaat caatggggaa tcaatacttg gcttgttttc
    40501 ttatctataa tatttacgag cgtcatccag aacttttttg acggtttcag tccttttccg
    40561 gaagaaagca tgcagcagca cttattgagt tttctagtcg ataatttact tttattcgca
    40621 ttcaactatg cattgtttta cattgcgcta gtagttgtac ggggtggcag accaaaaagt
    40681 aaccttttat tttcagtttt ccaaagaaag tattttggtt cgatacttgg catcaatttg
    40741 atcaattcag tcatcaactg gctactcaac agtttaatct ttctgcccat gtttttaatc
    40801 agcggagtga gtacttatat gcagctgctt ttcagttcaa atgcggtacc tacgggtgtc
    40861 atgccagaag attttcttga tatcagcttt gttttatcga tgatagggat gatttttgtt
    40921 tcagcactca tcatgagtat tgttggcggt ttattccaat ttgctgcatg gacaaagttc
    40981 gactatcctg atttgtcggt tattcaatgt ttgaaatatg gctggttttt attgaaagat
    41041 agaattggta cgtatatttt gttgcagctg tcttttatcg gctggtattt gctaggagca
    41101 atcgctttgt tcatcggtct tttgtgggtc attgtttatg tgaatgtgtc agttgcagaa
    41161 ttttatgaac aagcacggat tgaaaaagga ggtccagacg cctattttac ttagcatgta
    41221 agcagtttat tcatcaaaaa aataactttt gtggtaggat aaatctttga gggggaatgt
    41281 acgatgaaat taactgtttt aggatgctta ggagcgtatc cttataaaaa tcaagggaca
    41341 acaggttatt tgcttcaatc tgacgggttc aatttgttga tcgatgcagg tagtgctacg
    41401 ctgatcaaat tacaagaaca ccttgatcca cttgatctag atgctgtgat ccttagccat
    41461 tatcatcatg atcatattgc tgaccttggt gtattacagt attactggca acttcatcct
    41521 aagagaaatc cggagacatt gctttcaatt tatggacaca caaaagattc cattcacttt
    41581 gaagaattga cgttggaaaa tgtctcaaaa ggacatcctt attttgaagc tgaagaatta
    41641 aaaattggtc cttttctgat tacttttatg gaaacaatcc atccagtagt atgttacgcc
    41701 atgcgtatcg tagaagaaac aacggggaaa gtattcgtat ttacaggtga ttcaggttat
    41761 ttggaaagtt tcgctgattt tgcgaaagat gctgatttgt ttctagcaga tacctatctt
    41821 tttgaaggaa atgaacatca tcatgcccat ttcacttcaa aagaagctgg agaacttgcg
    41881 aaatcagcta acgtaaagaa acttgtactt acacacctac ctcagtttgg tgatttagaa
    41941 caattgaaaa atgaagcgca aaaggcagca ggcaaaggga ttgatataga acttgctgca
    42001 gttgacaaag tgtttaacat ttaggaggaa gaacatgatt tttgtaccaa atgaaaacca
    42061 cgacccaaga atcaatttag caattgaaca atatttgctg caagaaatgc ctttagatga
    42121 acctattttg ctcttttata tcaatgaacc ttcaatcatc atcggcagaa accaaaatac
    42181 gcttgaagaa atcaatcgag attatgtgga agaaaatggc attcatgttg tccgtcgctt
    42241 aagtggaggc ggagctgtct accatgattt tggaaacctg aactttagtt ttatcatgcc
    42301 tgatgatggg gattcattcc gtgactttgc gaaagtaaca cagccaatca tccaagcact
    42361 tcatgaattg ggtgttgctg gggcggaatt gaaaggccga aatgatctag tcattgatgg
    42421 catgaaattt tctggcaacg cgatgtatgc taccaacggt cggatgtttg ctcatggaac
    42481 aattatgttc gactctgata tcaatgaagt agtcaatgca ttaaaagtaa aaaaagacaa
    42541 aatcgaatca aaaggaatca aatcgatccg ttctcgtgta acgaatatca aaccatttct
    42601 tccagaagaa aagcaaaaaa tgacaacaga agaatttcgt caagaaatct tgttgaaaat
    42661 tttcggcgta gagtcagtag aagaagtaaa aacgtacgaa ttgactgatg aagattggaa
    42721 aaaaatcaat cgaatctctg aggaatatta tcgaaattgg gattggaatt acgggaagtc
    42781 tccagatttc aatttctctc gccaaaaacg tttttctatc ggttcgattg aagtccattt
    42841 gaatgtctca gaaggaatga tcaaagaagc aaaaatcttt ggcgatttct tcggactagg
    42901 agatatctct gacgtggaaa aaaaattggt tggacagaaa tatgataaag catctctatc
    42961 aaaaatagtc agccaaattg atgtgaagaa atattttggt gcgatagaac cagaagaatt
    43021 gcttacctta ctttattgaa aataaaaaat agcggaatcc acatatatgg attccgctat
    43081 tttttataca ggattcgggt aatttcgaga gagttgaaca gtgatccgat caatgaaagt
    43141 atctttttcc tgcgttagtg ttcctgtgta acgatccgct acgtctttca tcatcattaa
    43201 gtcaaaacgt tcctgatcat ctaattcttc tgtgatgcct cgactaaata ggtttgtatc
    43261 gtaatgtgca ctatgttcgc aacaaatgac gaaatgttcc tcttgttcgt gtatcgacaa
    43321 ataaattttt cgatacagtg gattttcgat ggcatgagtt tctctaaagg aatgctctaa
    43381 agcgtggatc aaaagttgag ccagatcgtc atcgttgata ggaagttctt cgggaagatc
    43441 tgcttggaag gttatctgaa tattccgttt ggcagctaac ttctggtaac gcgctaagat
    43501 aagatttgtc acctggtggt tgcaaaaaga acacagcatt tcgaaatttt ttgcttcttc
    43561 taatatcttt tccacatagt ttttagcttt tgtttggtcc gtatgcatta aatcttgcag
    43621 attctccatc tcttggacaa attccaggcg aagtgtattt acttcttgga tatgctgtcg
    43681 aagctgctca taatgttgct ccaacaaatc atttttgatt tttaagaaat ctacttgtct
    43741 ccgatctttg tcggtattta agatgtgatc gattagattg tagctgataa taacgattag
    43801 aatgataata tataaaatcg tagaccaatt gatcgttgtt tgatagatac ctaatgccgt
    43861 ttggatgtaa atcaagcaat ggataatggc taccaagacg atccaaggtg tacaagctac
    43921 ataaaaacgg ttattcttat atgcttcgcc aatgcatgca agtgaagtga ctaaagtgct
    43981 tataacacta gcaatattag caatcggcat taattcagga agttctgcag gagtaaaagt
    44041 tgcataaagc agaacgccga taaaaatcaa aagttggaac gtacaaaaaa ttccgtacca
    44101 ttttttatag taaaacattc ggctccaata gtagcagatg atgaaagctg acgttaagat
    44161 aataaataaa tgagataaaa aagaatgaac gaatggttca aaaagaatac cacttaaaat
    44221 atcttctgat acagcttcaa atcctaatgc caaagcaaag caacttaaga gaataagtga
    44281 gtattcaaga cgtttttgtt tatacatcaa gtagatcgta tagaaaaagg tccctatagc
    44341 gataaaaaca gcgattatca tcgtcaatac ttgcggcact gattgtgaat aaataaaact
    44401 aatcaatggt ccagttgttc ctagataaac tttcggtggc agtccagcat agttctgata
    44461 aggagatgag actgtaaggg tcaatttttt tccgatataa tttgctggta aatctatcac
    44521 agccaatgag agtccgggat tgctttcttc ctgataatct ttccgttggt ataaaatctt
    44581 ttcgcctaga tatacagtaa tccattgatg gtttcctttg attagtaaat ttgcttcgtc
    44641 caacggtttt tcaagtgtcg tttccataat gaatgtttcg tctttatcca cggtaggaat
    44701 cgtacgagtg tacttgctgt caaacttaaa atcaggatca tcttttgtat agaaaaccca
    44761 cgaatctttt atttctttca tttgattgct gtccgcagga gaaaaaataa aataaaagaa
    44821 ataagcaatt cctgttaaaa ataacaatga taatataatg attatgctcc actttatacg
    44881 taaataaaaa gattcttttt tattatatat gttattaaaa aaagacataa aggtattcct
    44941 ttctaaaact tgtaatgtta gggtaaacgt tttttaaact aacgtcaatt atttataata
    45001 aaaaatgaga taaagatgag gaaatagaat tagaaacata taattattaa agggaaacat
    45061 ttttacagct ataatttgaa aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggtg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg tgataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tatattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt gatttttaaa
    69361 aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg gtagaaagtg
    69421 ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggataa
    71281 ggaaagtgaa gtaaatgagt cttaaaaata aaattcggcg gtttatggaa aagaaaaatc
    71341 taaatccgat gaacaatcgc aaaaaagtag gtatcatttt atttgctacg agtattggat
    71401 tgttcttttt atttgccgtc cgtttctcgt atatcgttat tggaggtcat gttgctggta
    71461 cctcattagc tgaaaaaaca aaacagttgt accaaggaag tgaagtagta aaagcaaaaa
    71521 gaggaacgat ttatgatcgt aacggtgtgg cgctcgcaga agatgcctcc tcttattcaa
    71581 ttaaagcgat actctcaaaa acatatacct ctggggataa aaaactgtat gttgaagaaa
    71641 agaattttga taaaatagca gaaatcctgc ataagaatct ttctatagac aaaaaagatg
    71701 cactgaatat tttagaggac ggcgcaaaaa aagagctgta tcaagttgaa tttggtagct
    71761 atgggaaaaa tatctcccaa gaaaccaagc aaaacatcga agcggacatg aaaaaagaag
    71821 gtgtcgctgg tctttatttt gtcgaccatc aggctcggat gtatccaaat ggcgtctttt
    71881 cttctcattt tattggatac gcagttccag acaaagatga gaatggctta gttggtaaac
    71941 taggtttgga gtctgcttac aatgatatct tgagcggtaa agatggtaag attatttatc
    72001 aaaaagataa ttttcaaaat cctctgccag gtacagtggc agaagaagaa aaagctgtcg
    72061 acggacaaga tatctacacg actttagaca gcagactaca aagttattta gaaacactga
    72121 tggatcaagt aaatgaagaa tatcagccag aagaattgac agcagtcctg atgaaagcaa
    72181 aaaccggaga aatcttggca atgggacaac gacctacttt caatcctgaa acaatggaag
    72241 gattgactgg aaaagatgct atctggcgta atttcttggt acaagatagt tatgaaccag
    72301 gatcaaccat gaaagttttc actactgcag ctgctatcga agaaggagaa ttcaacgaga
    72361 atgaaacctt ccaatctgga aaaatccaag tagaagatgc tacgatcaat gaccatgact
    72421 ttggtgaaaa aggtgtgctg accatgcgtc aagctctttc atggtcaagt aacgtcggga
    72481 tggtcatact ggaacagcga ttaggcggac gatggtataa ctatttacaa aaactgggat
    72541 ttggacaaag tactcattct ggattagatg atgaagtaaa cggtgcttta cctacattaa
    72601 atattgtcga ccgagcaatg agtgcttatg gacaagcggt aggtgtgacg aatttccaaa
    72661 tgatgaaagc tttcacttct attgcgaata acggtacaat gattcaacct cgatatatca
    72721 gcaaagtggt ggatccccaa actggagaag agcgaacaac tcaaacagaa gttctagggc
    72781 aacctttttc aaaagaaaca acagaaaaag tccgtgaata tatgagagat gttgtcgaaa
    72841 gcgaaaacta cggtagtgct tatggtgtat atagtgtacc tggatacaat gtatcggcaa
    72901 aaaccggaac agcccaaatc gcttctgata cagggggata tcaaacagga gatacagcct
    72961 acctgtattc gattgtggag atggttcctt ctgaagatcc agactatgtc ttgtatctaa
    73021 caatgaaaca ccctaagaca tatgatcgaa tggcattggc taaaatcgca aatccattga
    73081 tgaaacgggc aatggatttt aaagaaactg aagaagattc agatacagaa acaaaaacag
    73141 aaaaagtatc cgtagccgat tatcgtaatc ttgaagcgga cgttgcagca gctgatgctc
    73201 aaaaaagtgg actgcaacct gtagtgatcg gtaatggtaa aaaagtacaa aaacaatcta
    73261 ctgccaacgg tgatcagttg atctctggag aaaaactgat cctatatact ggtggtgata
    73321 agctgatgcc tgacgtaaca ggatggtcaa aagcagatat catgaagctg gggaaaatcc
    73381 tcggtattga agttagtttt gatggagatg gttattgtgt caaacaagaa cttgctccat
    73441 atgaaaaaat cactgaagac aaacttagtt ttactttaga agaataagaa gagaaatagg
    73501 agagaaaaga gcatggaatg gacacaagca ttgattccca ttgtcagcag ttgtgcaatg
    73561 acaattgccg caatgccgct atttattggt tattttcaaa tgaaaaagca aggtcaggcg
    73621 attcgtgagg agggaccaaa gtggcacaat agcaaagccg gaactcctac aatgggcggc
    73681 ttagtgtttc tgatcggctc tattttgaca ggaatttggg ttggagcttg gcaaaaacag
    73741 ctaactccta ctcttttcat cttgcttttt gtattagcgt tatacggagt aatcggcttt
    73801 cttgatgatt ttataaaaat attcaagaaa agaaacatgg gactgaactc gaagcagaaa
    73861 ttgattggac agattctagg gggaatcatc ttttatcttg tttaccgttc tgaaggttat
    73921 ccaggtgtat tgaatttctt cggactagat ctacctttag gaatcattta tggtattttc
    73981 gctctcttct ggcttgttgg attttcaaat gcagtaaatc tgacagatgg catcgatgga
    74041 ttagttgctg gcttaggaag tatctctttt gcagcttacg gtctaattgc ttggcatcag
    74101 catcagtatg atgtattaat catttgctta agtgttttag gaggtttact gggtttcttc
    74161 gtctacaaca gaaaacctgc caagattttt atgggagatg tcggttcatt agcgttgggc
    74221 ggacttttag cggcaatttc tataatgcta aaccaagaat ggacattgct tttgattggt
    74281 ttgatctatg ttatggaaac agcaagtgtg atgcttcaag ttacttcctt taagcttaca
    74341 ggaaaacgaa tttttaaaat gtctccaatt catcatcact ttgaaatgtg cggatggtcg
    74401 gagtggaaga ttgatacagt tttttggttg atcagcattg tgacttcgtt gatcacatta
    74461 tggatcgttt ggtaggagat gacgggaaat gaaaaaaata tcaacatatg aaaataagaa
    74521 agtgcttgtc ttaggactcg caaaaagcgg agtaagtgcg gccaaattat tacatgaatt
    74581 gggcgcactt gtcaccgtta atgatggaaa accttttgac gaaaatccgg aagcacaaga
    74641 gctgctttct ttagggataa aagtaataac aggtagtcat ccaatcgaat tgttggatga
    74701 agaattttca ttgatggtca aaaatccagg gattccctac agtcatcctt tagtagcaaa
    74761 agcccaagaa atgggtattc cggtaattac ggaagttgag ctagcttacg aagtagcgga
    74821 atgcccaatt attgggatta caggaacgaa cggaaaaaca acgacaacaa cgatgacagg
    74881 actactactg aatgcaggag cagatcaagg aattgcacgt ttagcgggta atattgggta
    74941 tccagcaagt ggtgtagcgc aagaagcaaa atcagaagat aaaattgtga tggaattgtc
    75001 tagcttccaa ctcatgggaa tcacagattt ccgccctcat atagcggtga ttaccaatat
    75061 ctatgaagca catattgatt atcatggtac aagaaaagaa tatgtcaaag ctaaatggaa
    75121 ccttcaaaaa aacatgacag aaaaagatta tctgatcctt aactggaatc agtcagaact
    75181 acaagaatta gcgcaaagaa caaaagcacg cgtactgcct ttctcgacaa aagaagtgtt
    75241 ggaagacggt gtgtatgctg acgattactc aatatactat aaaaaagaaa aaataatgga
    75301 aatatctgaa cttggcgtac caggtaagca taatgtagaa aatgcactag ctgctatttc
    75361 tgtagcaaaa ttgtatggta tatcaaatga agctatacga gaaacgttgc attttttcca
    75421 tggcgtacca catcgtacgc aatatgtagg agaaatccaa ggcagaaaat tttataatga
    75481 ttcaaaagca accaatattt tagcgactaa aatggctcta agtggatttg aaacgtctaa
    75541 ggtcgtgtta ttggctggcg gattagacag aggaaataca tttgatgaat taattccttc
    75601 attaaaagga atcaaagcaa tggtcgtatt tggccaaaca aaagaaaagt tgatggatgc
    75661 tggaaaaaaa gcaggcatcg agacaatagt aacagccgat tctgtagaac aagcagttcc
    75721 tttagcatta gaaaacagta cagatggtga tgtagtttta ttatcaccag cgaatgccag
    75781 ctgggatcaa tacccaaatt ttgaaactag aggaaacaga ttcatggaag ctgtgaaccg
    75841 attaaaatag aaaaagtaga agcgagcgat aaaaaatgaa aattttggtt acaggcggag
    75901 gaacaggggg acatatttat ccagctcttg cctttgtcaa ttatgtaaag actcaagaac
    75961 cgaatgctga attcatgtat gtgggagcaa aacgaggtct agaaaacaaa atcgtccctg
    76021 atacaggaat gcctttccat accttggaga ttcaaggatt taaacgaaaa atttccatgc
    76081 ataacatcaa gacggtccga ttgtttctta agagtatccg tcaagcaaaa aaaatcctca
    76141 gtgattttca accagatatc gttatcggta ctggaggata tgtttccgga gcggtagtgt
    76201 acgctgcagc caaaatgggt attccaacag ttatccatga acaaaacagt gtaccaggtg
    76261 ttaccaataa atttttaagc cgatatgtgg atcggatcgc tctttcattt aaagatgcgg
    76321 cttccttttt tcctgaaaac aaagcagttc ttgtaggtaa tcctcgagca caagaagtag
    76381 cagatactaa aaaatcagat attttgaaaa catttgattt ggatccagaa aagaaaacag
    76441 tcttgatttt tggcggtagt caaggagcac ttaaaatcaa tcaagcagta tcagtttttt
    76501 taagtgaata tattccttct tcttaccaag ttttgtatgc ttcaggagat agatattatg
    76561 aagagatcct aaataaaata aatcctgaaa tacaaaatat tagtgtccag ccttatatca
    76621 aaaatatggc agaggtcatg gcttccagtg atctgctggt ggggcgtgct ggtgcaactt
    76681 cgatcgcaga attcacagct ctggggttac cggcagtgtt ggttcccagc ccatatgtta
    76741 cgaatgatca tcagactaaa aatgcaatga gtcttgttca cgcaggagca gcaaaaatga
    76801 ttgcagataa tgaactaaca ggtgaatcac taagtcagac agtcaacgaa atcatgggtg
    76861 atgaagaatt gcaaaagcaa atgtgccgag cttctaaaga acaaggaatc cctgatgctt
    76921 caaaacgtct ttatgactta gtaaaacaaa taatcaaaaa ataaaggcgg tggtcttagt
    76981 gagtaagaaa aaagaaccaa aaaaattgtc tcatccgtct tctgatgaaa acaatttgac
    77041 tccttggcaa aaggctaacc gaaaatatct ggcagaacaa gagatgaaaa accaagagcc
    77101 aaaaaaagaa gacataacat tagatacacc cctttcagat tctgaagaag aaaaaacggt
    77161 tcaagaggaa cagcaagaag aaagccagtc cgagaaaaaa atcgaatttt ttgaagagat
    77221 caagcaaaag aaaaacggtg gaccatataa cggttctttt ttgaaccggc tgcccaattt
    77281 aaaaagtcaa cggcacaaag tactatttcg tcggttagct ttgatcatca ctgtattggg
    77341 tataccgctg atttttttga tctattatgt ttctccttat agcaaattac aagcagttgc
    77401 agtatcaggc aataagacag tcaacagcca agaaatcatc tctgatacaa aattgtcatt
    77461 aggagaaaat gtttggggac agtattttca tcgatctact tatatcgatc gccttaaaaa
    77521 agcacagcca agaatcgaaa cagcaaatat acatttcaaa gggatgaatg aattcgattt
    77581 ggatgtaaca gaatataaag agattgcttt gatcgcaaaa aacaatcaat actacccagt
    77641 gattgaaaat ggaacagtat tagatgaaaa agtagcaaat cctacaaaaa atctccctat
    77701 cttggaagag ttcaaagact ctgcaaaaat caaagaatta acaaagcaat acaatcagtt
    77761 atcatcagaa ttacaaaaag caatttctga aatcaagtac acgccaagag caagcaataa
    77821 aaatctgatc caattgaata tgaatgacgg caatcaagtt attgtaaata tcaataatct
    77881 tgcgaaccaa atgaaatatt attcgcaagt agccaaagat atggatgaaa aaggtgtgat
    77941 cgacatggaa gttggtatct tctcgcatcc ttacggtagc actcaagaaa cggaagaatc
    78001 gggccaatcg gaagaaacaa ctgaaagtga agaaaatgcg gatcaaacaa acgaatcaag
    78061 tgaagaggca gaaacgcaaa aagcacaaac acctggatcg tctagcacaa acggatcatc
    78121 tgattcaaat gattcaagtg aaacaagtca aatagaagat aatccaagta caactccgtc
    78181 aagtttaaat gaaaattgat aaaacaactt taaaaagtaa gaatgtactt tctaaaaacc
    78241 agtaatttat ggtagaattg gaagcagtga atatatctat taataagtat attttaaaac
    78301 ggacgctagt tgttcgcttg tatatggaat agtaagtagg agggaatccc attcatggca
    78361 aaaacaggaa tgtatgtagg ccttgatatt ggaacgacat ctgttaaagt tgtcgtggct
    78421 gaatatatcg acagccaaat gaatattatt ggagtaggaa acgcaaaatc agaagggatt
    78481 aaccgaggca ttatcgttga tatcgataaa acggtccaag cgatacaacg agcagtacga
    78541 caagcagaag aaaaagcagg tatccagatc aaaggcgtaa gtgtcggttt gccagcaaac
    78601 atgcttgaag tagaaaattg ccagggaatg attgcagtta acggagattc aaaggaaatc
    78661 accgatgaag atgtcagaaa tgtggcttca gctgcccttg ttcgttcaat acctcctgaa
    78721 cgtcaaatcg tgtcaatatt gccacaagat tttactgtcg atgggttcga gggaatcaaa
    78781 gatcctcgtg gaatgatcgg cgtaagatta gaaatgtacg gtctgttgtt tacaggacct
    78841 aaaacgatca tccataacat acgtaaatgc gtggaaaatg ccggattaat cgtcaacgaa
    78901 atggtgatta ctcctttagc gctgactgaa tcaattcttt ctgacggaga aaaagatttt
    78961 ggtacgatcg tcattgatat gggtggcggc caaacaacaa cggctgttat gcatgataag
    79021 caattgaagt ttaccaatct tgaccaagaa ggtggcgaat ttgtcactaa agatatctct
    79081 attgtattaa atacgtcatt taacaatgca gaagcgttga aaataaacta cggggatgca
    79141 tacccagaac ggacatcacc agatgaagaa tttccagtag atgtgattgg tcagtcagaa
    79201 ccagtgaaag tcgatgaacg ctacttgtca gaaattattt cagctcgaat ggaacagatt
    79261 ttcaacaaag caaaagatgc attggaccaa atcgaagcat tagagttgcc aggtggcgtc
    79321 gtattgacag gcggagctgc tagtcttcct ggtgttgtgg acttggcaca agaaatcttc
    79381 ggcgtaaatg taaaattgta tgttccaaat cacatggggc tgagaaaccc ggtatttaca
    79441 aatgtaataa gtatcgtgga ttattcagca aacttgagtg aagtgtatca attggcaaaa
    79501 attgctgtta cgggtgaaac ctcagcagct cgtcaaatgg tagttgaaca agaaacaaca
    79561 aacacatatg agagctatga agcacctgaa gaaacaatct acgatgagcc ggaaccaaaa
    79621 gagtccggag aaaatgtaaa aaataaaatc aagggtttct ttacaaatat ttttgattaa
    79681 ttcatcctgg gaggaataag atatggaatt ctcaattgat aataatatca atgacggcgc
    79741 agtaatcaaa gtcatcggag tcggtggtgg cggtggaaat gctgtaaacc gaatgattga
    79801 agaaaacgtt aaaggtgttg aattcattac agccaacaca gacgtgcaag cattaaaaaa
    79861 ttcaaaagct gaaacagtta tccaattagg ccccaaatat actcgtggtt taggtgctgg
    79921 ttctcagcca gaagttggac aaaaagcggc agaagaaagt gaacaatcct tacgcgaagc
    79981 tttagacggt gcagatatga ttttcatcac tgcaggaatg ggtggaggaa ccggtacagg
    80041 tgctgcacca atcgttgcag gtatcgcgaa agaattgggc gcattgactg ttggtgtcgt
    80101 gacacgtcca ttcacttttg aaggaccgaa acgtggccgt tttgctgcag aaggtatcgc
    80161 tcgtttgaaa gaaaatgtgg atacattatt aattatctca aataaccgtt tattagaagt
    80221 tgtagataaa aagacaccga tgcttgaagc tttccgtgaa gcagataatg ttttacgaca
    80281 aggtgtacaa ggtatctctg atttgatcac agcgccaggt tacgttaacc ttgactttgc
    80341 tgacgtgaaa acagtgatgg aaaaccaagg tacagcattg atggggatcg gtgtggctag
    80401 tggagaagat cgcgtagtag aagcaacgaa aaaagcaatc tcctctccat tgcttgaaac
    80461 atctattgat ggagctgaac aagtacttct taacatcaca ggcggtttgg atatgacatt
    80521 gttcgaagca caagatgctt cagatatcgt agcaaatgca gcaactggcg atgtaaatat
    80581 cattctaggt acatctatca atgaagaaat gggcgatgaa atccgtgtga cggtcatcgc
    80641 aacaggtatc gatgaatcaa aaaaggaacg caagtctagc cgaccagcta gacaagcaca
    80701 aatgcaatca cctgctcaaa agactgtatt agatatggat caagctaaac caacttcttc
    80761 agaagaagaa aacagttttg gcgattggga tatcagacgt gaacaaaatg ttcgtcctag
    80821 agttgatgat tccaattttg acaatatcga aaaaaaagaa tttgatacat tcaaccgcga
    80881 agaaacaaaa tctcatggcg atgatgaatt aaatacgcca ccgtttttcc gtcgtaaaaa
    80941 ataaaggaga ggaagagcac atgattgctg acaacttgca gaaaatcaag caagaaattc
    81001 aggattcgtg tgctcttgtt catcgtgatc cgaaagaagt tacattagta gctgtaacaa
    81061 aatctgttga atccgctcaa gctgaagaat tggttagagc tggcgttatg aattgtgcag
    81121 aaaaccgagt agataaatta ttagaaaaga aacaagattt atttgatttt cctgaaataa
    81181 agtggcattt aattggtaat ttacagcgca gaaaggtaaa attgattgta aatgaaattg
    81241 attactttca tgcgttggac agtttaagat tagcagaaga aatccagaag cggttagaga
    81301 aagaattatc ctgttttatt gaagtaaatg tttctggtga ggaatcaaaa catggaattt
    81361 caccagatga gcttttaccg tttgtggaat ctttagctgc ctgcacaaaa atcaaggttg
    81421 ttgggttgat gactatggcg cctaaagaag cttctgatga gcaaatccat aaagtgtttg
    81481 gtacgctgaa agaattgcgt gatcttgttc aagcaaaagg ttatgcccat gcaccatgta
    81541 gtgaattaag tatggggatg agtcaagact ttcaaattgc gattgaagaa ggtgcaacat
    81601 ttatccgtgt aggaacagcg ctattcaaag acgaataaag gaggaacaaa aatgccgctt
    81661 ttaaacagag gagcaattgc taattttttc ggattagctg atgaggaaga gtacgaatac
    81721 caagattatc ctgaaacaac aaaaaaggct gtacagccaa ctaaaaaaaa tacaacacag
    81781 aatcaatcaa ctcattctgt atctgctgcg aatactcatg aaaaacaaaa aacggcgact
    81841 tcacgtcctg taacgcatga aagtattcag ccggctgaaa agaaaaaagt aattgaacta
    81901 catcaatcac ctacaaaaac tgtagcgaaa gaaagaacag cttcaagaac ctctacacaa
    81961 cctaaagcaa atcttgctgg aaaaatcact gtaatggaac caagagctta ttctgaagct
    82021 atggcgattg ctaaacgaat cattgctgga gaagcaacct tagtgaattt tcatttagta
    82081 gaagaaaaac aagcgagaag aatcgttgat tttctaacag gaacagttta tgcactagat
    82141 ggagatatca aacgtgttgg agatgagatt tttctttgta caccgactgg gatggagatt
    82201 gacagttcaa ccgctcaatc ttttgcagat gcgaatttgt ttgatctgta agaggaggaa
    82261 ctacgattta tactattgca ctattacttc atttacttca acgggcagcc tatttctata
    82321 gcattatctt gatggtatat gcattgctct cttggtttcc aggcgggtat caatcagggc
    82381 taggacgatt attagctaag atctgcgaac cgtatatcag tttgttcgat cgtctgcctt
    82441 tgaggattgg acccttggat ttcacaattt taggggcaat cctgatcttg aacttagccg
    82501 tacaaggttt agcacagatc gttatatgga taactgtcca tttagtttat tgattgaagc
    82561 aacaaaatct ttattctcag aatagatagg aggggaaaat tttggatgca aatgtatacc
    82621 agcactttcg ggcagatgaa cgtacattta tcgattcggt aggcgattgg attgaacagg
    82681 ttcaaggaca atatgcaccc tatctgaccg aatttcttga cccaagacaa tcctatattt
    82741 tagaaacact gattcgacaa agcagtgatt tgcgtttcat gttttatggc ggatatgaac
    82801 aggcagaaag aaaaagatgt ttgattttcc ccgattatta cgaacctgta gaggaagatt
    82861 ttgaaacagc attgtatgaa atccattatc ctagcaaatt tgccagccta agtcatggga
    82921 aaatccttgg aactttagtg ggaacgggga tcaaacgctc ttactttggc gatatcatct
    82981 cggacggtga tcgctggcaa gtatttattg caaatgaggt ggatcatttt gttgctgcac
    83041 aagtaacaaa gattggaaag gttgctgtac gcttggaacc aatcaaatac acagaaatga
    83101 ttatgccgaa agatagctgg acacaagaaa gaggaacagt tagttccatg cgactagaca
    83161 gtgtgatctc tgagatttat aatatttcca gacagcggtc caagcagctg atcgaagctg
    83221 gtaaagtaaa agtgaactgg acagaaaata caagacctga ttttgtactt gaactattag
    83281 atattatttc agtcagaggt tatggcagag tccagatcca agaacttgag gggaagacga
    83341 aaaaagaaaa gtacagggta ctgttcggtg tattacgtaa ataaaataaa aaggtggttt
    83401 actcatggct ttaactccat tagatatcca aaataagaca ttcccgacaa aaatgcgggg
    83461 atataatcaa gacgaagtag atgatttctt agatttagtt gttcgtgact atgaggaatt
    83521 gactcaaaga aatcgagaat tagaaaaagc agtcaaacat tctgaagaaa aacttgagta
    83581 cttcaatgaa ttaaaagatg ctttgaacca atcaatcatc gtagctcaag atacggctga
    83641 taaagtaaaa acaagtgcaa gcaaggaatc cgaagtgatc gttacttctg cacaaaacaa
    83701 agcagatgag ttagttgcga acgctgaaaa acgtgcacat caattaacaa ctgatgcaga
    83761 agaaaaagca agaaaaatct tgacagatgc aacagaaaaa gcaagacagc ttgcgacaga
    83821 aactgaagat cttaagaaaa aaacacgagt attccatcaa cgtatcagct tgatgcttga
    83881 gtctcaatta gaacaagtga aaagtccgga atgggatgaa attttacaac cattctccag
    83941 ctacgtgact gacagccatg aagtgatcaa agaagtttta gcaaaacagc ttgacaatga
    84001 aaatgatact gatgtaaact cagacacagg agtcatagaa gcacctatga cggcatttga
    84061 tacacaggct attgatatct cgatcgtgcc tggtgaaaat gaaaacgagt agaacagaaa
    84121 agcactttgt tattcttaaa gcgagccgat gagagtggaa gttcggtaag acactgcatg
    84181 gtgaaagatc ctctacttga gacctgcttt tccgaaatta gagtaagaag cagcggctga
    84241 cctcgttatt ggtcacagag agtttgcact agatagatgc aactaaattt gggtggtacc
    84301 acggcatgtt cgtcccttgc ggctgaacat gcttttttgt gtccggaaaa caaataaagg
    84361 agtgtatggt tgaatgaaaa tgaaagaaac cttgcaatta ggaaaaacaa aattccctat
    84421 gcgtggtaat ttgccaaacc gagaaggcga gtggcaaaaa gaatgggaag aaaatcgaat
    84481 ctaccaaaaa agacaagagt tgaacgaagg aaaacctagc tttgttcttc atgatggacc
    84541 tccatatgcc aatggtaata tccatttagg acattcattg aataaaatca gtaaagacat
    84601 tatcattcgt tcaaaatcaa tgtctggcta tcgtgcacca tatgttccag gatgggatac
    84661 acatggattg ccgattgaac aagtattggc taataaaggc gtgaaacgta aagaaatgtc
    84721 catggcagaa tacttggaaa aatgtcgtga atatgcactt tcccaagtag ataagcaacg
    84781 agcagatttc aaacgcctag gagttgcagg agattgggaa catccttatg ttacattaga
    84841 tccttcttat gaagctgcac aagtacgcgt atttggtaaa atggctgaaa aaggctatat
    84901 ttacaaagga ttgaaaccaa tttactggtc tccgtcaagt gagtcttctt tagcggaagc
    84961 tgaaattgaa tataaagatg taaaatctcc atctattttt gtagctttca atgtcaaaga
    85021 cggcaaagat attcttgatg aagatacagc ttttgtcatt tggacgacaa caccatggac
    85081 attgccagca aaccaaggta ttgctgtaaa tccaaaattt acgtatgtat tggtggaagc
    85141 cgatggccgt aagtttgtcg tagcgaaaga tttgctagaa acagtccaat cagaaatcgg
    85201 ttgggaaaat gtaacagttc taaaagaatt tgctggacaa gaaatggaat atatgactgc
    85261 aagtcatcca ttctatgaac gtgaatcact tgtgatttta ggcgatcatg ttactttaga
    85321 cgctggtact ggattagtcc atactgctcc aggacatggg gaagatgact atatcgctgg
    85381 tagcaaatat aaactatctg tagtgtcacc tgtagactca aaaggattgt ttacagaaga
    85441 agcacctgga tttgaaggta tcttttatga caaagcaaat cctatgatca ctgatctatt
    85501 aaaagaaaaa ggagctttgc tgaagctaga tttctttact catagttatc ctcacgattg
    85561 gcggacgaaa aagcctgtga tctatcgggc aactccacaa tggtttgcat ctatcgataa
    85621 attccgtcag aatattttgg atgaagtaga aaaagtagag tgggttatcc catggggtaa
    85681 aacacgtttg tataatatga tccgtgaccg cggcgattgg gtaatttccc gtcagcgtgc
    85741 atggggagta ccacttccga ttttctatgc tgaaaatgga gaagcaatca tcacaccaga
    85801 aacaatcgaa catgtggcaa aattatttgc tgaacatgga tcaattatct ggtttgaaaa
    85861 agaagcgaaa gaacttcttc ctgaaggatt tacccaccca ggttctccta atggcgaatt
    85921 tacaaaagaa aaagatatca tggatgtctg gtttgattct ggttcttctc atgaagctgt
    85981 tttacgtcag cgaccagaat tatcattccc agcagatatg tatttagaag gatcagacca
    86041 atatcgtggc tggttcaact caagtatcac gactagtgtg gctatcaatg gtgtagcacc
    86101 atacaaatca gttatttctc aaggatttgc tttagatggt gaaggccgta agatgagtaa
    86161 atctttagga aacatcattg caccagaaaa agtgatcaaa caatttggtg cagatatcct
    86221 tcgcttatgg gtatctagtg tagattatga agcagatgtt cgtgtttcta tggatatctt
    86281 aagtcaagtg gcagaagtat atcgtaaaat cagaaatacg atgcgtttct tattagcgaa
    86341 tacagaagat ttcgatccta aaaaagatac tgtttcgtac aatgatttac gttctgtaga
    86401 caaatatatg accgttcgat tgaaccaagt aatcaaagaa atccgagaag aagggtacga
    86461 caaatataac ttcatgcata tttaccgtac agttatgaac ttcttgacgg ttgatctatc
    86521 gtcattctac ctggattttg ctaaagatgt agtttatatt gaagcagaag atgattatca
    86581 acgtcgttgc atgcaaactg ttttctatca aacagctgta gctttgacaa aattattgac
    86641 tcctatcatt ccgcatacag cagaagaaat ctggtcattc ctgaaagaag aagaggagta
    86701 cgttcagtta agcgagtttc ctggttatga agagtttgca aaccaagaag aattgatgga
    86761 tacctggact gctttcatgg acttccgtga taatgtctta aaagcattgg aagaagcaag
    86821 aaacagcaaa ttgattggta aatctttgga agcaaaacta actgtttatc caaaacaaca
    86881 agttcgtgaa atgttaaaag ctttggatgc agatattgca caattattga tcgtttcacc
    86941 agactacttt gaagttatgg cagcagatga acaagtgcca gataacgcta tggtatttga
    87001 tgatgttgct attacagtgg aaaaagcaga cggggaaact tgcgatcgct gtcgccaagt
    87061 tcgtaaagat gtaggagtag atgaaaaact tcctcatcta tgcggtcgtt gtgcaaaaat
    87121 cgttgaagac ttctatcctg aagctgtagc tgaaggattc gaagaaaagt aaaagggaaa
    87181 agggggtgtg acatgttctt tgtcacaccc ccttttgtta tcaatcgttt aattttccac
    87241 gttcacgata ccagttatct ggttgccaga tccattcgaa tccgtctttt tcaagtagtt
    87301 cgaaagctgc tttaggtccc attgatccag ctttgtagtt gggaaaatcc ggttgtgttt
    87361 ggtcccaagc ttttcgaatg acatccacga tatgccaaga ttgagcgact tcttcccaat
    87421 gagagaagtt cgttccatca ccattcaacg catctaatag taatttttcg taagcttctg
    87481 ggctattttc aaccatttct gcactatttc taaattccaa tttgattggt tccgtttcaa
    87541 atccttgccc tacttctttc ccattcaagg ataaagaaaa tccttcagtt ggctgaatat
    87601 agatcgttag aacattaggt ggaagtgtcg tatcgtcaca tggttcatcg acagatgttt
    87661 tgaatacatt aacaggaact tgtttgaata cgatgttgat ccgagtccct ttttcagtca
    87721 aacgtttgcc tgtacgtaca tagaaaggaa cacctgacca acggaagtta tcgatagtga
    87781 atttgcctgc gacgaatgtt tcagtctctg attgagcatc cactttgtct tcttcgcgat
    87841 agcccttgaa ttgtacacca tccaattcac cttgagcata ttgcccgcga acgaagtttt
    87901 ctaacacttc ttcttcgtta taaatgcgga tagctttcaa tgctttgatc ttttctgtac
    87961 ggatttcttt ttcggaaaat gctactggcg gttccattgc aagtaatgct acaacctgta
    88021 aaatatgatt ttgcaccatg tctttaagtg cgccactatg atcgtagtag cccccgcgat
    88081 cttctacacc gaggttttcg ccaaaagtaa tttggatatt gtcgatatag cgattgttcc
    88141 attgagcctc aaaaatatta ttggcaaaac ggatagctga gatgttttgg atcatttctt
    88201 ttcctaaata atgatcaatc ctgaaaatat cttgttctgg gaatacttct ctgatttgct
    88261 ggttcaattc aaaagcagac tggtaatcag aaccgaacgg tttttctatg atcaaacgat
    88321 tgaagccatt ttttgtcata atattttgtg atttcaaatg agaaacgatc gttccaaaaa
    88381 attgaggtgc catagccaaa taatagacac ggttaccgtt taattgatag tgtccatcta
    88441 atcggtcaga caattctttt aatgtctgat aatgcgttga atcatttaca tcatgggatt
    88501 gatagtaaaa atggcttgca aaggtagttg cttcttcatc tgaaggattc aatgcacgga
    88561 ttgtttcttt gacaacttca cggtagtgct catcgctcca gggacggcga gcggttccga
    88621 ttacagcaaa atgctcgcct aaatttcctt ttctgtaaag gcggaacaaa gacgggtaca
    88681 atttacgctg ggctaggtca cctgtaccgc cgaatatcgt aaacaataca tttttttcat
    88741 tagacatgtg gatacactcc tttatatttt atcgacaaaa atcgtgctgg ccgccttaaa
    88801 gctgacgggg attttctttc tatcattttg gatagtgatc ggtccttcat aagctgcgat
    88861 gtcaacgatc tcatattctt cgttgatatt caggtcaata gtgactaagt aatccaacaa
    88921 ttctttttca tcaagcactc gtgcgatacg cacttttgta ccgacaggat aggactccaa
    88981 tgtttgtcgg cgttcttcat ggacaacttc ctctttttta ggaatcgatc ctccatgagg
    89041 acaatgttca ggatgattca aatagttttc taaatgatct gcaagatgtt ccgaagtcac
    89101 atgttccaat acttcagcat catcatggac ttcattccag ctatagtcta aatgttcaac
    89161 taaaaaaact tcccataagc gatgtttgcg aatcagactg ctagcttttt gcagtccgct
    89221 tgcagtcaat tgtacacctt gataagggga atgttctaca agctcttctt tcacaagttt
    89281 agaaatcatt tcactgacag atgcagctga gacatctaga ctagatacga tttgtttatt
    89341 gttgactttc gttgtatctc cacctagttc taaaatgatt ttcaaataat cttctcgatt
    89401 tggtgtcata ttcgatcatc ctttcatggt aaaaaaccat cattagtaag tgtaacaaaa
    89461 aaaacgttaa ttgactattt ttctaaataa aaaacaaagg atttttagac gtttttacaa
    89521 caaaaaacga aagatgatag agaagactca ttctttcgtt tataaaggat atatatatac
    89581 attgggaggg atctattttt cagataacaa cttatatgaa gtgtctgcag attcgtcata
    89641 aagagtttgt tcgggataag aaaagataag ataaaaacca tactgatcac gtacgactaa
    89701 acgatattca tctatttcta ccacagatgt gccaagagac tgaccgttga tcaaaaacgt
    89761 gtaatcagat gtaatctgta attgttgttt ttgctggcta tcactaaaga accatgtacc
    89821 ttgatacttt gagagtcctt ctgacttttc cgcttgtttt ttctttttca agtaaataaa
    89881 acttgagaga acggtaatga gtgaaccaag aaaatagatc atttttttta tcaccaaatc
    89941 actcctttat gagaaaataa tcgcatagac atattctttc ttctttattt cattgtaccg
    90001 aataaaagct aaaatttctc taagactttc gactggtttt tttactgttt ttctacaaat
    90061 tatgatagga tacatagtag gaagaaaggt gacataattt gaagtatcag caagtggaaa
    90121 tagctttttt tattgaccgc ccgaatcggt ttatagcaca ttgtatgaaa aaagacggag
    90181 aaataattat tgcgcatgtc aaaaatacag gtagaggaaa agaggtcctg ataccaggcg
    90241 ctgaagtggc tattgtattt gctcctggac ctaaacggaa aaccgcctat gatctgattg
    90301 ctgtaaaaaa gaagggtgac tggtttaata tcgatagtca attgcctaat cggctggcaa
    90361 ttgatggtat tttagacggc acgatccttt taccaggatt aactggtcca tttacggtat
    90421 acaagcgtga agtaacttat cttcactcca aatttgatat ttatttagag acggtggtcg
    90481 gacaaaaagc atttgttgaa gtcaaaggta tgacacttga aaataaagcg attggtgctt
    90541 ttcctgatgc gcccacactc agaggattga aacatatagg agaattaacg tatgccgcac
    90601 aagatggtta tgccgcttat gtcttgttta ttgctcagtt cgaacatctt catctggcaa
    90661 cgatccatga agaaatgcaa ccagcactag ctgatatggt tcgacatgcg cagcaaagcg
    90721 gagttcaaat cctcgcctat aattgtcaag tatcggcaga tgaggtaact gtcaagcagg
    90781 ccattccatt tgatgtagat atcccttttg aagatcctat acaatagaaa gaaggtaaaa
    90841 taatgatcaa cttaggtatt atcggaacaa attggattac tcatcaattt gtccaagcag
    90901 ctttaagcac aaaaaaatat gaattgacag cggtatattc tagacatttg gaaaaagcac
    90961 aggaatttgg ttctcattat gaaggggata tcgaattcgc aacagatttg aagacttttt
    91021 tcaatattac tcatatggac accatttata ttgcttctcc gaatagtctt cactttagtc
    91081 aagctaagca agcaattttg gcaggaaaaa atgtgatagt tgaaaagcca gctttttcga
    91141 cgccaaaaga aatggatgaa atcatccatt tggcaaatga acacaatgtg tatttttttg
    91201 aagcagcaag aaatatccat gaatcaggtt ttaaaaagat tgccgattac ttaccattaa
    91261 aagacgagat aatcggtgca aatttcagct atatgaaata ttcttcgcgc tatgaccaag
    91321 tattagatgg agaagaaccg aatatcttct cgactcattt ctcaggtggt gcattgatgg
    91381 atttaggtgt ttaccttgta tatgcagctg ttgcttggtt tggaatgcca aaagaagtcc
    91441 attatttccc aagaaagatt tctactggtg tagatggtct tggatggggg atcttacgtt
    91501 atgagaattt tgatgtatcg atccagccag gtaaaatcgg tgattcttat ttaccgtcag
    91561 agatttattt tgactcagga acgctagtga tgaatggagt caatgcaatt gaacaagcac
    91621 aatttcatga tcgcgcgcat aaagaaatca ttgatttggc ggtaacagct gcagaaaatc
    91681 caatggcaga tgaagcagag gattttgcca atgtcatggc tcatccgaaa gatccagctt
    91741 ggggattgtt gtatgaagag tggatcgagc tagctagaaa tgtgaaccaa gtgatttatg
    91801 atttaagaaa aaatggcggc atcaaattcg atgcagataa tgaggaagat ttttaatgaa
    91861 cgaatttgta caagtatttc ccgaaaattg gcagaaaaaa tatgaggata aagggtttat
    91921 ctcaccttct cttattcaac gagcagtttt tcagccacta agtaataaac aaagtatagt
    91981 agcggtttct cctacaggtt caggtaaaac actggcttat ctttggcctc tactactaaa
    92041 cgtggaacca ggtgaagcaa gtgcgttggt catttttgct tcttctcaag aactagctat
    92101 tcaagtagca gatgttgcac gtgaatgggg aaaagacaaa gagttgaaag tccaatcttt
    92161 ggtgggcgga gccaacgtca aacgtcagat tgagggtttg aaggaaaaac cagaaatctt
    92221 gattggtaca ccaggaagaa tattggaatt gatgaaagca aaaaaaataa aagcacatca
    92281 agtgaaaaca atggtatttg atgaagcaga ccagctattt gacgctggga acagccaaat
    92341 cattgatcaa attcttcatc aagctccaac agagtatcag ctagcttttt tttcagcgac
    92401 agcagatcgt tcccttgaaa gcattgaaaa aatcactggg aaaacgtttg agacaattga
    92461 cgtgacagca gaggacgatt ctcgaaaagg actgagacat tactttttac gtgtaccgat
    92521 acgaaagaaa gatgactact tgagacgtct cacgcatata gaagattttc atggtctgat
    92581 tttctttaat caactgactg aattaggcgt aatggaagaa aaattgctgt atagaggtgt
    92641 accggtagga agtctggcct ctgatcagaa caagctactc cgaaaagcag cgctagaaca
    92701 attcaaaaag aaaatggtca gagcactttt gaccacagat gtggcggcta gaggtttaga
    92761 tattacaggt cttccttatg tagtgaatgc agaagttccg ttaagtgaag aagcttattt
    92821 gcatcgttcg ggaagaactg gtcgaatggg taatgaagga atagtaatta cactcgtaca
    92881 agataataat ctaagagatt taaaacggct tttacgtcca tcaaatataa cacttgaaga
    92941 gattttttta tacggaggta agctgcaaac tgagcagcca accaaagaag atgcagctcc
    93001 tgcagtaaat aaaaagtatg cgaaaacttt ttctggaaag gagcagaacc cagaatataa
    93061 caaagaaaaa ataagaaaaa aagttaaaaa taaatcaaaa aaagagagaa ataaaggagc
    93121 aaggcgcaaa taagcgcctt tttatgctat gattatgaaa acgggaacaa aattggttgc
    93181 cagaggaggg gttatgtgaa agaacgtcaa gaagagatct tgcagctatt gacagaaaac
    93241 caacaaggat tgacagcaag tgatgtagct gagcgcttaa ctatcgatcg aagcaatgca
    93301 agccgatatt taagtgaact atacaaggcc catcatattg taaaaaccgc tggccgacca
    93361 gtcgtttact ctttgccaac ggaaaagtca aaatctgatg aagtgcatgt cgactcttct
    93421 acgcaagtga cttttgaaac actcgttgga gaaaatgatt ctttaaaagt cagcatacag
    93481 caggcaaaag ctgcgattct ttatccaccg cgggggttgc atacgattat ttttggagaa
    93541 actggtacag ggaagtcgat gtttgctgaa tgtatgtatc attttgcaat cgattcagag
    93601 atgctttctg cagatgcgcc atttgtttct ttcaattgtg cggattatgc tcaaaatccg
    93661 caactgctct ttggacacat ctttgggatc aaaaaagggg cttacacagg agcagctcaa
    93721 gatagtcccg gtctaatagc caaagcagac ggcggtatat tgtttttaga tgagatccac
    93781 cgtttaccgc cggaagggca ggaaatgctg tttactttca ttgataaagg tatttaccgt
    93841 ccgcttggag aaagtgcaca agtacatgaa gcatctgttc agatcattgg ggcgacgact
    93901 gaatcttcag aaagtttctt atctacgttc aatcgacgga ttcctatggc aatcaccttg
    93961 ccgaatcttg cttcacgttc actggatgag cgttatgaaa tcatctctct ttttatcaaa
    94021 caagaagcga atcgtttgaa tcaacgtatc gatatcgaaa aagaagcgat tcttgccttc
    94081 atgctttatg atgcggaagg aaatatcggt caagtgaaac gagacttgaa actagtctgt
    94141 gcaaaatctt ttttacatta ccgtactcat catgagaaaa agctaatcat tcgaaaagaa
    94201 gaactttccc ttcaagtaca aaaaggatta ctgaaaatca aggaaatacc ggaacgtctc
    94261 gaccgattca tggacagcaa aagtcagtat ttgacatttg aaccaggatt tgctgatgtt
    94321 gtctggtcac aagatccaga acgaaacatg caggtctata acgatattga ggaaaaagtc
    94381 acttctcttt ccgaaaccgg tgtggagaac attgatctag agaccctcat ttcaaaagat
    94441 gtggatgctt atttccagac atatgtcaaa gaattgacta aaagttcgat tcccaaagat
    94501 cttttgccag atgaaatctg gcggttaacc aatcaattgt atgatgtggc tgaaaaacgg
    94561 ttagaccgta tttataatga aaaagctcgt tttgcttttg ctttgcatct gcaaagtaca
    94621 ttggatcgtg tgagagaagg tcatatgatc gtccacccag atttgaataa cgtacggaaa
    94681 aattttaaga gggaattcca ggtagcaatc gatctttcaa cgatcattga agaagaagaa
    94741 caagttgaga ttccttttga tgaaatcggc tttattagta tgtttctttc tatcaatcta
    94801 ggagaaagtg agcctgttaa agaaaacaaa gtagatgttc tcatattgat gcacggcaga
    94861 cagactgctt caagcatgtt ggagatggca caagaactat taggaacaaa agtagggaaa
    94921 gcttttaata tgccactggt tatggaagtt caaacaatgt atgaagaagt gttacaatat
    94981 gtcaaaaact atcaagagca tttgacgaat ggcctactct tgttaacaga tatgggatca
    95041 ttaaacacct tcagtgattt gatttatgaa gagactggca ttcggacgaa agctatcacg
    95101 atgacaagta ccatgattgt gatagaagcg atacggatgg caagtgttgg aagaagctta
    95161 gaagatattt atcaaaatat ccagctttcc tttgaatcga tcgtacgtga tcagttcaaa
    95221 gcggaaaagt ctgaaacttt acagcgtaaa aaagccgtaa tcgtgacatg ctttactggt
    95281 gaaggagtag ctgccaaatt atatcagcgt attatgccag tgattaatca aaataaggta
    95341 gaactgatcc agatgcagtt tttagaacgt gaatcattca aaaaacacat cgatgcctta
    95401 ttggaagaat atgagatcaa agcaattgcg ggaacagttg atgttgatta tcaaaatatc
    95461 ccattttttt cagcctatga cgtttttgat gatgaaaaac taaatatttt aaagcgtata
    95521 gctgatgatg agatcccgac agctaaaatt gtcgattcac ttgctggatc attaagcgat
    95581 gtcttttcta ttgatgaact gatccgttca ttgcaaaaga cagttcagca gatccagacc
    95641 gatttgtcga ttatcgtgga acctggagta gatactggaa tcgttatcca tttagccttc
    95701 atgttagacg gattgatcaa acaagaaagc catcggcaat ttgagaaact gtctattttc
    95761 tcaaaaattt atcgtttgga aatggatatc gttcgggcaa acttgatggc actagaacga
    95821 aaatatcagg taaaaattcc agaagatgat atcgcatttc ttacacaaat gtttcttgaa
    95881 aataaaataa aaaaatgaac acactaatca tactgtttac acactaaaca tctgtgtgcg
    95941 cactataaaa aagagctaaa aagcatgaaa acgctatttc agctcttttt tttattggca
    96001 tgcttcttgc gttatataaa agtgtaaaaa aataaaagga gtgttaaaaa tggcaaaaaa
    96061 aacaatcatg ttagtttgtt cagcagggat gagtacgagt ttattggtca caaaaatgca
    96121 aaaagcagca gaagaaaaag ggatggaagc cgatattttt gcggtctctg cctcagatgc
    96181 agataataat ttagaatcta agaatgtcga tgtattatta ttaggtcctc aagtacgttt
    96241 catgaaagct caatttgaac aaaaacttgc gcctaaaggt attccattag atgtcatcaa
    96301 tatgcaagac tatggcatga tgaacggaga aaaagttctt gcacaagcag aaaatctaat
    96361 gaaataaatc aagtatgcag ttgggggtat aacaacgtgg aagatcaaca aaatctagaa
    96421 gccatcatgg ggttaatcat gtttggcggt aatgcaaaga gcgatgcaat ggaagcgatt
    96481 gcggctgcta aaatcggtga ttttgagtta gcggatagga aaatcgctga tgcagaagaa
    96541 tcacttatac aagcgcatca tgcacaaaca gacatgttga cacaagaagc acaaggaaat
    96601 catatgcaag tgacattatt gactgttcac agtcaagatc acttaatgac atctattgcg
    96661 tttactgatt tagcaaaaga aatcatcgaa ctttatcgtc gcgtatacag cgaataaata
    96721 caacttcttt tttgaacgga agaagaaaaa tttttgaacg gattttttat tttgttataa
    96781 ggagaactct ctttatataa aaaacttata ggaggaagta aaaaatgaac ggactatcaa
    96841 gttggatgga gaaatacatc ctgccggttg ccgcaaaaat cggagcgcaa aaacatttag
    96901 ttgctttgcg tgatgctttt atcggcacac tgcccgcaac aatggcggga tcagtcgctg
    96961 taatgatcaa tgcaattatt cgtgatttac cgcaacagtt taacagtacc tatgctgaca
    97021 gtttagcagc agacaaagga atctttgccg tattgaatgt catcatcgga atcaatggtt
    97081 ttgtctggaa cggtacacta gcaatcgccg gattgatctt tgccttttct tgggggtata
    97141 atcttgcccg agcttatgga gtaaatgatc tagctggggg gatcgttggt ttagctacct
    97201 tgattcaagg tatttccttt ggtccagcat tatcagcagc attagatgtg aatgttcctt
    97261 caaatgtcgc agatgcaatc aatagttctg agattggtgc aacgattgca gatggcacac
    97321 tgtcagttgg attatggggt tggctaaaac tagatcattt gaatggaaac gcttatttta
    97381 cagttatgat catgggagct atttcagtca ttattttttg taaattgatg cttgccaaca
    97441 ttacgatcaa aatgcctgat tcagtaccac cagcagtatc taaagcattt gcagccattt
    97501 taccagcgac gatcgcttta tacgtcattg ctattatcaa ttatatcgta ggtcgtgtag
    97561 ctgatgggca actgatcatt gatttggtgc aaaaatatat tgcagaacca ttcctaggat
    97621 tatctcaagg gttgggagca gtattgatcg tcacagtatt tgttcaagta ttctggttct
    97681 ttggtattca tggatcaaat gtattggcac cagtgctaga gggaatctgg ggacaagcac
    97741 aactaatcaa tattgatatt ttccaaaaag gttataacgg aaaaactggt acaccagccg
    97801 tgttagatgc aatcgaagat ggaaaagctt atatgtgggt ccgcggatcg ttcgatgctt
    97861 ttgcatggtt tggcggatca ggcggaacga tcgtcttact gatagctatc ttgattttct
    97921 ctaaacgtgc agattatcta acagtagcta aattatccat tgggcctggt atcttcaata
    97981 tcaacgaacc agtgatgttt ggtctgccaa tcgtattgaa tgcaatcatg tttatcccat
    98041 tcttgattgc tccagtagta gcaacagcaa ttggatggac agctacttat cttggcctag
    98101 tcgctccggt atcgcagcaa gtcacatggg tagtaccgcc gttcttattg tcattcttag
    98161 caacaggagc ggattggcgg gcaccgatcg taacattagt atgtatggtc gtgactttct
    98221 tgatttgggc accatttgtc atctctgcaa acaaaatgga ccctgccgca ggcgaacaac
    98281 aataagatga acgtgaggag cgggacgctt taagtttcgt tcctcataat gaattttcga
    98341 ggaggaactg aaatgattac aattgccagt gcaatgcaac aagatgaaat caaagaattg
    98401 ttagaaggat acaatgaaga aggaatgact tttacattta aagaaaaaca aggaatcaag
    98461 ctgttctttg aaacaagtgc agaagatccg gaagttgcgg ctaaaaaagc aaaggaacta
    98521 atcaaagcac agccttgggg aacagtcctt tattttcaat caacagctgt ttagaaaatg
    98581 gtttaaaaag ataggatggt tgagatgata aaaaacggtt tatttttatg tagtattggt
    98641 tctttgatcg tgttgtatag tttgaatcca cattcgcaaa ggtatgattt gtatagtatg
    98701 gtcacaggtc tttttctaac aggattagga atctatttct tcatgaaggg gaaaaaaaga
    98761 gaagaagcaa aggagaaaaa taactaatgg aaatcacgaa aaaattaaat attccagcat
    98821 cgttttttta cgataaagtt atggactctg tccttttcga tgtacgtaaa gcgaccggca
    98881 aatcagtaac tagaaaacag ctgaaaaatt tggagtacgt caaacaattc tcgcaaaata
    98941 accgggctcg cataaaaatc gaagaagtca ttgaaaacca gtcttataag tttcgtacat
    99001 cgacaacgaa gaatgaattc gtcgttcatt atcaaatcaa accattggac gattcgacct
    99061 gtgaggttca ttacacagaa aaaatggagt cttatggcat gcttcaaaag ttgaatgata
    99121 tgcttttagg aacaatcttg atgtatttta aacggagacg tttcaaaaaa atgctagata
    99181 tgatcgaagc aacgtattaa atcaatgaaa catggtacta tttagttatt gaaaaatgaa
    99241 gtaagctaga aggaattttt cataggaaga tagatctttc ctgcgaatcc tcactagctt
    99301 ttttgtagga aggggcagca aaatgacaaa caaagtaaga gagctaggtg tatcttcgat
    99361 tgaggaaatg tttgatttag ccacttatgc atttaatggg gcagatacac ctgaaaggcg
    99421 agaacgtttt cgtacacttg cggagaattc ttggaattac ggattttttg atgaggagga
    99481 tcggctaaca agtcaagtca tggcgacccc ttttccagtg aatttttacg gacaagagta
    99541 cctaatggcc ggcattggct atgttgcttc ttatccagaa gcaaggggac aaggcgggat
    99601 caatcagatc atggaaaaga tccttgaaga ttgccgtgat cgtaaagtaa gcttatctta
    99661 tctggcgcca ttctcctatc ccttctatcg gcgctatggc tatgaacaat catttgataa
    99721 aatcagttat caactaaaca gtcgtgatgt gccgtttatc aaaaaaaaat ctggaaaaat
    99781 aaagcgtatg gattttgaag atgcaaaagc tgcaatcaga agaatttatg aacagatgcc
    99841 ggaaaaccaa cgagctggtc tgaagcgcga agactggtgg tatacgtata aattcaagca
    99901 aaaaggcaat taccagtttg ctttgcattt tgatgataat gaggaagcaa cgggatatat
    99961 cgtttatcag cttgcaacgt cttcctttat tattgcggag tggggatttt tggatcatga
   100021 tgctttttgc agccttgttc gcttcgtaag ttctcacaat ggtgcttttg aaacatttga
   100081 atattcatgc ggctacggcg gtaatgatca aaattatcta ttagaaaatc catttgcttc
   100141 tgtaatgatc acaccttata tgatggcgag gatcgtagat atttctttgt ttttggaaaa
   100201 ttatccattt aaaaagagac aagctgcatt tgccctacaa atagaagaag atcattatgc
   100261 gaaatggaat gaaggaatcg tggaagtaac aatcgaaaat ggaaaaaatc atctctcaaa
   100321 agtagaacaa acaaaactcc caatcgttcg aggaagtatc caacatatca cgcagctatt
   100381 attagggtat cgtaaagtgg aagagttggt attccaagaa agaatacagg tgacaaaaga
   100441 atatgaagaa acgttaagct caatcttgcc acagcaacag ccaattctta atgactattt
   100501 ttgataaaaa acgggtgatg acaatatttt tgtcaccacc cttttgtttt tcatttggca
   100561 tttgaaggaa aatgttaaag taaatcctct tttttcgtaa atttgaattt tttgttttct
   100621 tttgttttag ggttttcttt tttgtggtct tggattgctt ctttcgtaat cttttcccga
   100681 ttttttttag atgaatctaa gcgttctgcg tatacttttt cttttggctt atcattcatt
   100741 ggaaaggacc tccctacatt atttcattct acctctagtt tatcatctgt taaggactag
   100801 tggaaacgtt ttgcctaact tataagctga tttttttagc agataagctt gcaagtaaaa
   100861 aacaaacaag ctacaattga tttattgaaa ttgttcctgt agctcagtag gatagagcaa
   100921 tcgcctccta agcgataggt cgctggttca attccagtca ggaacgtata aataacccct
   100981 gtatcctttg cggtacaggg gtttgttttg tatttgtgcc aaaaatgtgc caaactagtt
   101041 atcattttta tataaactat cgaacacagt attgattttt tctttatcct gatcttcaag
   101101 ctctcgaaca atatgaagat aagtagacat tgtagtttct aaactgctat gtcctaaacg
   101161 tttcgatacg ctaagtatat ttactccttg ataaagtaaa atagatgcat gtgtatgcct
   101221 tagtccatgc aaagtaaatt gcttttcaat ccctaattct tttaattttt tgcgcaaata
   101281 tttgctgacg gcgtttgatg aaactaatcc attttttaag ttgaaaaaaa caaaattatg
   101341 agggtttttg atttcaaaat tctcgaataa ttctttttga ttgattttaa acttttttaa
   101401 gagatcaatc gtatgtttat caatggaaat tttcctattt gaagtttcgt tttttgtttt
   101461 tccccattca tttaatttat aattccatgt tttattaata gtgatgattt gatcttcgaa
   101521 atcgatatct tcccatgtta atcctagaag ttcagcaaat cgcattccag tggcaccagc
   101581 aactaacacg agcataggag aagagtactg cgcagaaagg ttttcttcta cgagtttcat
   101641 taaagattta aattgatcat aatctaaata tttatcttct tttggcttca atgaatcttt
   101701 tcctttgatt actgcttttc tagttggatc aaacggaatt aatccttctt ctacggcatc
   101761 tttcaacgac gctctaatat ggttattaaa cttaataacg gtagatttta catggtcttt
   101821 agcatactta tttaaaaagc gttgatatcc cactctatct aaatcagaaa tcaataccgc
   101881 tggcatatat ttctttatgt tcattaacgt atcttcgtat tttctataag tgataggaga
   101941 tactgttcct tctttataaa gttgcatcca atcctcaaag taatctgata ataatagatt
   102001 tttgcgatcc cctttaaggc ctttgttcaa gttatattct aattcgttgg cggcatcttt
   102061 tgcttctcct tttgtcttaa atcctgattt tcttatcttc gtgtattttc cgtcatcttt
   102121 tttgtatgaa atttcgtatt gccaactatt tccacgtttg actaatcttg ccataattga
   102181 atcagctctc tttctctgat acaataggaa ctataaagaa gcccattgtt tgggttttat
   102241 tattttttgc acatcctttt tgcttgccgg cgcaaggatg tgctatttgt cgttttaatg
   102301 gtataattgg atgtgtatta gatcatccaa tcagaggtgt ttattatgat taaagtgatt
   102361 tttaaaagaa taactgaact tccagagttt agattatttg ttgattattg gtatgtctgg
   102421 ttttttattg ttgcattgct gataggtcta gatgtcatat tagaaagaaa acttaagtaa
   102481 gagttgagtt aataaattga attcctaaat gagatatttt gtagcccata ttttgtttgc
   102541 cgacatcacc taatactatg gagctaatcg ttttttctaa cagaccaaaa tcagataatc
   102601 tatttaagct accatctatt agctcttgtg aatagccaga catgctgata tttccagtga
   102661 aattttcgtt tccacgactc attaagcatg ctaacaattg aatctcaatc gatgttaatt
   102721 gattcagtac aagaagataa tactcctcgt tatcccatga agcgttgtta attcgaagta
   102781 aacaattctt ataaagattt ttatacatat ctattttatt ttgtgccttt gatttttcta
   102841 cctcgtcatt tatcccttcg aatattccaa tgagttggtc cttgttctct aagttgaaaa
   102901 catcttctgg aatttgatcg cgaatgtttt ctaatgattc gtttaaattt ttgtagaatt
   102961 tctcgatgcg tttgaaacgc ttctcgtttt tagacccaaa ataaagtgac tgcacaacgc
   103021 caccaatata aggaattgct ccaataccgc cttcaactat taattcaaga tattcttttt
   103081 tggttagttt ttcattgcta ttatccatag ttacctccta ttttgtcatt tcctttacaa
   103141 gcattgtgac tcctgatggc actcttttgt ataggtttta ttattgtgca caatctaact
   103201 cttagtgggg cgtggttcat ttatttttta cttactttac tattaatcat atcccattga
   103261 gcataggatt tttctatgtt cgatcctctt gaactaattt ctcctgtaaa agttacttta
   103321 tcgccctttg taaaggtatc agcattgttt aagtccttcg caaaaattac atatgaaact
   103381 ttaggtgttg cagaaatatc attccaactt ttatcatcgt actctttgtc tgctataatg
   103441 gctattctag tagtcattga ttcgataaca gttccttcaa aagtatatgt tttaccacta
   103501 atatatttag taaaagctgt attttgctca gtagctggag taatagaata ataactatct
   103561 aagaaagcac cccagtcatg attatttgtc tctaaaaatt cttcaaattg agttaggctt
   103621 ttattgctgc tgttagatgt agtagtttga gtatcagatg atgagctttc ctgtttgtta
   103681 ttgtcatttg cctcgtttga tgaggaaagc gagaaaccta cggtagtaaa aataatcccg
   103741 ataataagga gaatcatagg tgttttctta tttgtttttt tgataaatct tacaattaac
   103801 atgattaaac ctataataaa taaaacaata ccagtaaaac caaatatacc gtccattaat
   103861 agatcctctt tctcttttga tattgaatat tataaaccaa gcaattcttt tttcttaaaa
   103921 tcgaattctt cttgattaat aatcccttca tctaacaact ctttatactt tttaatttca
   103981 tctgcacttg aaatttgtgt ttctttggaa ttattatcta atatagattg ttgcttctct
   104041 atatattttt ttaaattttc catttcattc caatattttt ttgtaaacat aacggtgttt
   104101 tcatctttcg tggccgctaa tatacctccg cgactttcgt ttccgcctag caaggtaaat
   104161 tgtatataac cattactcat acctggtttt tttaattgta cggctgatat atttttaaag
   104221 gggatagttt tttctccttt aataccttga ttaactaaat ttataaatcc ttttctaata
   104281 attgaaatag aatcatcagt tactttaatc aaggtttttc ctggagattt tattaaaatc
   104341 tctttttcca ttttttcttc ctcatttctg tgatatgatt ttttttgtag aagctcatat
   104401 atgaggaaag agcccgtgtt gcagcacggg cttttttaat gttttgctga aatcggtttt
   104461 tttaataatt cttgatgtat tcatacatat tgccttgcgt aagaatattt tttcttaaaa
   104521 tagcattggc agacagcata acaagtgtat ctgagcttat tctgaataga ataatactcc
   104581 ataaattttt cgagattaaa ctgagattca tcagtcagtt cgttctcaat atagatattt
   104641 aataaaatta gaatagctat tttatctgct tctgtttcaa attttgagtg aaaagttgta
   104701 gaagtatcgt acaaaactga aaattcaaaa tgagaggcgc tgaaatgtgc aagttcatga
   104761 gataaatgaa aggcttctgc agtttcaccg tatagatttt cattcaaaaa aatgattctg
   104821 ggttttggat agtagaaacc aggctctttc atctccatat aaactacttt caaattgtat
   104881 tcgctcaaca tttctttcaa tttcaaatac atacaaacca tcactccaac tattcatttt
   104941 cctctaaagc tttagcaatt gcaatcgctt tacgcattgt ctccttagat atttcttttc
   105001 catcaaaaga aaaaacagta tcgtcttctg ataaatccac atgtttaggg gtttctcttt
   105061 cttctctacc tagaaggtag tctacagaga catcgaaata gtcagcaatc cgacttaatt
   105121 catctgaatt aggagtatta tttttccact ttgctagata accgttagaa tatccaaaat
   105181 taatttctaa ctgccgtata gatatctttt tcctcttcgc caagtctttt attatttcat
   105241 aggtattcat cgataaaaca acctttctaa atgtttacaa aaaaagttta gaaaaatacg
   105301 cagaaataat ttgactaatt ctgagtaacg agctatacta tatcttgtaa acagatttaa
   105361 caactaaaaa gacaacaaaa aacactattg atatgtaaat gcagaccgcc aagaaagctt
   105421 taaaatcaat gtttttatgt cttatttaat tatgctctta gtatagagta ttactcagat
   105481 actgtcaatt gaatttagaa aaaagttgtt aaatttgttt acgaatataa aagaaaggaa
   105541 tgagaaatat gaacacaccg caaattttta atttcgaaca aaacgaagtt cggacaattt
   105601 tagtaaatga tgaaccatat tttgtaggca aagacgttgc gagtgttttg ggttattcaa
   105661 acactaaaga tgctttgtcg cggcatgtag atttggaaga taagatgggg tcgcgaatca
   105721 cgacctcagg tcaatcaaga gagatgacaa tcatcaacga atctggtttg tacagtttaa
   105781 tcttaaaatc aaaacttccc tctgccaaaa aatttaaacg ttgggtaaca agtgaagtgt
   105841 tgccagcaat tagaaaacat ggaggttatc taactccaga aaaagtagaa gaagctttgc
   105901 ttaatccaga tacaatcatt caattagcaa ctcaactaaa agaagaaaga actggaagat
   105961 taatcgcaga acaaaagatt gcagagtacg aacctaaaat ctcctattta gatagcatat
   106021 tatcttctac agattcagta acaattagtc agattgcagc agattatggg atgtctccac
   106081 aacagatgaa taaattactt cataaactag gtattcagaa aaaagtcggt aaccaatggt
   106141 tattgtgcaa aaaacacatg aaccaaggat acacaaaatc tcatacaact gagatcccga
   106201 aagccgatgg tggcactaaa attgtaatga ataccaaatg gacacagaaa gggcgtctat
   106261 ttatctacga attactaaaa aaagaaggat attaccctca aatggattta gaggaaattg
   106321 gttagaaagg agttttagta tgactgacat tgcagaaatc actcaacgag atagagaaaa
   106381 aatcaaagaa tatgtcgaaa gttcaaagtt cttaacttac accatgcttg ctgaaagatt
   106441 tggaattagc aaaagctact tatctttaat tttaaacggt aaaaagactt ctgcagaagc
   106501 aaacagaatt atagattcga ttatcactat gtacgaattg taaagggagg aacagctaat
   106561 gcaatatcta gaagcaaaaa tcccaattcc agaaggctat gtaattatct cccaagtgga
   106621 ttatgaggag ttaaaaaaag ctgatgatac tggtagatgg atgacgttgc cagaagtgct
   106681 agaacggatt aacagaaaat atgattggtt tacttctaga gttttaaaga acccaagata
   106741 tagaaatatt atcgatatcg agaaaaacaa aaatggattt gtctattatc cagttgaagg
   106801 aagagacaca tatctatttt taagaagtaa aacacttgaa tttttagaaa caaatttttc
   106861 ggaaatctta aggaggcaag cggatgggaa aatttaatag agcgctagtg ttcagcgcac
   106921 cgctaatcat ctacgcttta ggactttggg gaagcaggca agcgttgata ggaacgattg
   106981 tttacatggt ttggattttt atggggcttg atgaagctga agctgagtac agagcgaaaa
   107041 agccaaccga gggggctgac taaaaatgaa tagaaaagag aaactagaat gtatattact
   107101 attactcagt ttaattcttt cactaatttc tctattggga agtttgtatt tttgatatca
   107161 acaattttgt ggatttgggt tctatttaga gtaaatatca tttttgtttg gtgattaagg
   107221 agtttattaa aattaatttt ccctacttca aatgcaaggt aacaagatat agcactttta
   107281 ggaggaatat ttagcggtac agcttcagag tatattctat tatcatcgac tgatcctcct
   107341 ttagcaatta atttcttaaa tggagtagct gaccatctgc ggtttaagtt agcggatgaa
   107401 agttctaaat taactaacat agctggttct gttgaatagt tagaaatgat tacttttgta
   107461 taaatcatat ctgcagcgaa gtaagaagca ttaagttcaa cttctagttg agggcgcatt
   107521 ccttttattt ttatccctgt taaaaacgta ctcaatataa aacttattat tgacatccat
   107581 tgaaaaattg ttaagtgaaa aaaattcaaa ataaacacca ccagttttta actaaattat
   107641 accaaaaagg agagaagaaa taatgcaaga attagtaatt ttgaaaaata aagaagctgt
   107701 gactacgagc ttacaagtgg cagaaagctt cgagaaaaaa catcaacatg ttttaagaga
   107761 tattgatgca ctaaaaaaag atgtgtccaa ttttggacag atgtttgtag aaggtaatga
   107821 accagattca tatggcagaa atcgacgagt tttcttcatt agtagagatg gatttttctt
   107881 gctggctatg gggtttacag gaaagaaagc tatctacttc aaacaaaaat acattgaagc
   107941 attcaacgaa atggaagatg ttattcgcaa gaatactgtt cctcaaacaa ttgaagatat
   108001 gatgatctat caattagaag aaatgaaaga tgttaaaaaa gatgtttcca tgcttaaaga
   108061 tactatgcga attagcggac aacaagagtt tgaaattaag caaaaaggaa atatgaaagt
   108121 tatgggagtt ctagggggaa aagaaagccg agcttatgaa gaaatcagca aaaaagtatt
   108181 ctcaaaattt tggtctgaat ttaaacgtac cttttcaatc ccaagatatg gcgagttacc
   108241 tcgtaagaga ttcgatgatg ctgtttcatt tattgaaatg tggttgccag aaactgcgat
   108301 ccgtatggaa attgatcaac tgaacagaca acagagactt tttggtgatg acaatgaata
   108361 gagctgaagc gctaagaata gggacggcaa ttgctaattg ctggtggaaa tactataaac
   108421 caatcatcct aagccaacaa catattgaca agcaaaaagc atggcaacaa ataaaaaagt
   108481 gactccgccg gcaagcaaag agtcacaaag aaaacacatc ataaggagat tttagcatat
   108541 ggaaaaagaa ctttccactc tagatcaata tttgattgat cctgattggg gcaagccgaa
   108601 aattgaggaa acaagtggtc gaaaaatcag acgaaatctt ttgacgaatg aagaactagc
   108661 ttgggatcaa gatgatttag gcaaccatgt aactatttgg gatcatgttt atcttatcca
   108721 tctatcgaag cattcgaata aacctgaata tatttacgtc atcgaagatg gcttgattga
   108781 tgcgctagaa gagtacgaca gagataactt gattgatatc tcttattacg gaccaggtaa
   108841 gaaatacatt gctgaaatgg aggcagaatt tgatgagtga aatcaaaggg acaacgaact
   108901 ttgaaaaact ttttagtcgt aagttaaata aaattctcaa gaaaaaagga aattttgatt
   108961 atttatcttg ggctcacgcg tgggagatta tgaaaaagaa tgatccacag gcaacggtaa
   109021 ctattaatga gtacaaacac tacagggttg tttctggaac tcatcaagac tttcttgttg
   109081 aggaatataa accttttctt atggatgaaa ctgggactta tgtatctgtc tcagtaacgg
   109141 ttaaaggaca cacggaaacc gaattatttc ctgttttaga ttatcgaaac caaccagttg
   109201 ttaaaccaaa tgcaatgcaa atcaataact cattgaagcg atgctttgtg aaagcattgg
   109261 ctctacacgg actgggatta tatgtatttc aaggggaaga tattccaaca ccacctagaa
   109321 tcgatacaaa gaaattaaac atgctagaga cgattctaga agctttcaat gagcagatgg
   109381 gtaaagatat gaccaaaacc ttaatcgaat atgttaatga gcagacagat aaattagggc
   109441 tcttagctga taacgttgaa actattgaac agttaagcta tgagcaatgt gccttgatgg
   109501 agcgagcaat agcagctaag agaaaagaat tagataagaa gtgatatgag tgtttaaacc
   109561 attaatcgat tcatattcag cggttctgaa aaagttcaaa ggaaaagaca taagcgcaac
   109621 catcaatgag gaagtgaaca ttgatcgact aaagacgatg tatgacggct acgatggtga
   109681 tcgagtcatt gaaattcgtt ttattgatcc tagacgtttc accgtacagc aacgaaactt
   109741 catctatgcg ctgataggcg atatttttat cgatacaggc atgccaacgg acttctggaa
   109801 ggaattcttc tactttcgtt ttgaaggtgt cacagggcgc aaaataagcc tgaaagacga
   109861 atcgaataca actgtgagtg atgccaatgt cttagcaaat atcatcttag atttcatctt
   109921 tgaacatcat attcctttca aagaaggcta tgagatttta cctgcgaatc aagaatatta
   109981 cttctacaaa tgcatcacaa aaagagtctg ctgcatctgt ggcaaaacag gagctgacat
   110041 cgatcacttt gacaaagcgc taggaagacg aaagcgcaaa gaagttgatc atgcagagta
   110101 cacatttgca gcactctgca gaatccatca cacagagaag cacaaaatag gtgtgattaa
   110161 tttcaaaaat aaatatcaaa tcaaagggat caaattaaac cagaaaacaa tcaaaaagtt
   110221 aaatattgga gggtaaaaat gacagaacat cgaagttatt atgcgattat accagccaac
   110281 gtaaggtacg acaaaagact taaaccaaat actaagttgt tatacggaga gataacggcc
   110341 ttgtgtaatg aaagaggctt ttgttgggca ggcaatgagt actttgcaga tttatatggt
   110401 gtgaataaag agaccatatc gcgatgggta agtgatttga ttaagtttgg atacttgaat
   110461 cgggaaatca tttacaaaga gggtaccaat caaataatca ataggtacct acgaattaat
   110521 caatacccta ttgacgaaaa acgcaatacc cctattgacg aaaaagtcaa agataataat
   110581 acatctatta ataatacatt taataataca aaagaatata taagagagtt accgccttcg
   110641 aaaaaatcga aggctaagcc cgtccgtcat aaatacggag agtataaaaa tgttcttttg
   110701 tcagatgagc agatggagaa actcaaaaca gaattcccta atgattacca agagcgaatc
   110761 gaacgactgt cagagtattg tgaatcatct ggtaagactt ataaaaacta tttggcaact
   110821 attcgaagtt gggcaaggaa agaaaaaagt gaacctaaga acgcaagcag tggatacaag
   110881 cgcacaggaa gacgagagaa gcttcctgaa tgggcaatcg accaagaagc ctatctcaag
   110941 aaaaaagcgc tagaacgagc taatagacaa tcaaaagcac cattctaaga ggtggaaaaa
   111001 tgaagatcga ttatctagaa ctaattaatg aaatagcgaa ttataaaaag ggcgaggaat
   111061 tagacgtcct gagagacgta tatgatcaac tcgaagaagc tggaattgaa ggaattaaga
   111121 atgatcgttc gagttggagt aagctcagat actatttcgc actttatatc gatacaacac
   111181 aattaagaaa tttagcatat accaaattac tatttgttga ttgtgttaaa ggcttgcaaa
   111241 aacatcttaa tgaacttgag caggtgtaat cagatggacc taaagacatt tacagcacag
   111301 attgaactaa tgcatcaaga agctttaaga caaagtgtat cgtacgaaga caagtggctc
   111361 aacacgttcc atggcggacg tgagagcgca cttgatcaag tactcaaatt actgaaagga
   111421 gaatgtcggg atggataaga aagcggcaat gcagcgaatt atcgaattga cttattcaga
   111481 agattggcaa aatgacaaag aagctgcttc agaagtgatg aggcttggaa gagcgatgtg
   111541 ggcagacaag agcaacaagc caagaccacg aaaaatcgca atttggcacg gtgacaaact
   111601 tctagtgata gggacagctg aacagttagc aagtctcaca ggcttgcacg agaaaatcgt
   111661 gaggaaaaga gcaaggtgtg gctacacaga cgctaagaag agaacgttta gatacgtgga
   111721 ggaatcatca tgacaacaga agaagtgatt caaatgcgta ttcgaagcct tcagcgtgag
   111781 attgacgatc tggaacgaac aaaggcagtg atggtcaatg aaacggcgag aaaggcaatc
   111841 gatttgcaca tagagaattt aagaagggaa atccatcgat tggaggaatg agcgtggata
   111901 agaaagcagc aatgaaaaga attgctgaat taaccaagtc agaatcttgg caagaagaca
   111961 aagaaatagt tgcagaagtc caaaagctcg gtaaatcaat gtggactgaa aagcccaaac
   112021 ggagaacgcc gagaaaaatt gcaatctggc atgatgaccg aattttagta acaggtactg
   112081 ctgaacagtt atctgaaatt actggattaa gcaaaaacat tatctgggat agagctagga
   112141 gcttatggat tgattcaaaa ggacgacagt ttaggtatgt ggaggagaga taatggatct
   112201 cattacacaa tacagtgaca tcatcctcaa gaaaatcatg atgaagattc agaaagataa
   112261 aaaatcaaaa gaacgagctg aattagttaa gttagaaatg gctgaaacag gagcaggagt
   112321 gcgaagtagc aggcattgga aagcagcagc aaacattgaa ttttattaca acgaaattca
   112381 aaaagggttc gatcagatgc gtgagctgga tcggcaaaca aattggagca agaaacttca
   112441 tcaagatcgt ttcaaatttg tagagaagta taaagaaata ttagaagagt atttgaggag
   112501 gacagcaaat gataaaaaaa ctcgttcaat tcagcatgga tttatatgat atcgaatcag
   112561 gagcaacact atctgtggaa tcggaccatc taatcataaa ttttggtgga aagcgccaga
   112621 ttattttgtg ggtagttgat gatgtactgt ttccagaaat tgttcatgat ttcgaagaat
   112681 caaaagcggt tgagtttgaa atagtgaaaa aagtaatgga attgattgaa aaatacgagg
   112741 aggacagcga atgataccga agtttagagc gtgggataaa cgaaagaacg taatgagaga
   112801 tgtagccgtc ttgcatttta ctaaaaacgg caaaacaaac tttattgaat attggataaa
   112861 tcctaccgaa ttgaaatcat atcacgtgcg aaacatcgac ctcatgcaat ccacaggaat
   112921 gaaagataag aatggtgtgg atatatttga aggggatata gtattagtca gcgtgcgaaa
   112981 tggcttcgat tacttagata ataaagtctg tattgtcaaa aattcaatag attattccgg
   113041 attagtttgt gccactgttg atgaagactt agagtatcaa atttttaaca cagagctgtt
   113101 tgaagaatac acgtacgaag tcaccggaaa tatatacgag aatagcgagt tattggagga
   113161 acagcgatga ataaacagga agcaatcaaa aagttagaaa gtattaaagc gataggaaat
   113221 gatgcaatag ctgcttgcta taacgagagt ataaattcag gtattacgtt aatgaaaaaa
   113281 atagacgaac cgcagaaacc agttattcca caactcgtgg ccggttggct tgagaaatct
   113341 acggaccctt ttacaaaagc tgaaaaaata gcgtatttaa tcaaatctaa agatggtgat
   113401 tcatattatt tctgtgattg gtttgtacga gatggcatag tgacgcaaga gcaaggagaa
   113461 gaattactcg cttgggcaac aagacaatca tatgaaacac tattgagcct atacaacggc
   113521 tacgaggttg agaaagagcc gttatgggca ataaagaatg ccgatggaaa ctatcttact
   113581 aaatgtgctt tatggggaaa agatggagta aattatagtt ttgaatgcaa tccatctcat
   113641 cgattgcttt tcactgataa agcaacagcg gatgctgcag cattgttggt gaatggaaca
   113701 gtggaagagg tggtagaaag atgaaactaa aagacggatt ttacgctagc agtcacggta
   113761 tcggcggttt aatgctagat atgccgacaa agaaccctaa aacacgcaag aaatcaaaat
   113821 tcaaagtcgg tgacatggtc cgctgtgaag cagaagagtt cgtttatccg ttcagaggat
   113881 acgttaaaaa gatactgtca aactcagcaa tcattcgtat tgaaaataca atgaagtgtg
   113941 atcgttcgac tgcaaaacac aagcattatt tagctgtagc gagattagtt gacatggaag
   114001 taatcaagag caaataaaaa aagccggatc gctccgactg attcaataaa tccaacacat
   114061 ttattatatc acataaagga gcggtttgac ttgatgcaat tgttacgaga ggtagatttc
   114121 aaacagacaa gatgtaatgc gagagatgtg ctgaagaact ttcggcgttt ggagcggatg
   114181 gcaggtcgct ctttgataga tattaagtcg ccgattataa cggatatgcc gaaggcaccg
   114241 aagcatggca ataaggcaga agacgcgatt attcagatga tggatataga aacggagaga
   114301 gatgcgattc tagcggcttt gatggctctt agtctgatta gtcgtcagat actctactac
   114361 agcttctgtg tgccagatag cttctcaaac tacagaatta gccgtgaagt gggttattca
   114421 gaaagaagta tacaacggat gaagtcggaa gctctaatag agtttgcaga agcatataaa
   114481 cacggaaaaa taattgctta taaataattt ggcggttttt tggcggaatg atggcggttt
   114541 ttagacattt accagtgtta ttatggtagt gtcgaaagat taggaaacag gatcgacaaa
   114601 ataaacgaag ggaggcaatc tccctcatcg ttttaaactt cttcttagat agacagcaac
   114661 taattatgaa gaaaaggatg tgaattcaac tcctcctaaa ttcttcatcg gttgctgttt
   114721 attttgatta gacagcagca ctcacaaaac taaacatgtt cttgtcgtct ttcaactgct
   114781 gctgtctatt aatttatgta ttggagggaa gaaaaatgaa attatcagta gaaggcactc
   114841 cagaagaaat acaagaattg ctccaagcta ttggtagtag caaggagcaa aaggtaagtg
   114901 tttctaattc agatattgac ggtatttgca attgtttaaa cagagaaaaa atatctaatc
   114961 cttactaaga gaaaatatgt tcgttaatga atttccaatt ttcctctgta gctctacctt
   115021 gataattttt ttgcagttca cagatgaata aggaatcgtt attatcaagt actgtattta
   115081 atttttcaca catttgattt ggattcaaat tagttttaac taaccaaaaa gatttttgta
   115141 gctttatata tgccccaaat tcttttatta tttcaaatac tttatcatac ttttgccctg
   115201 ggttattaag atcataacta atcatgtagg gtttatacat gttgtcttgc acatccttgt
   115261 tttatatttc agcggaccac tcgctgataa ataaaattat acgcttagta tttattttca
   115321 caatattaat ttatcgtaat aacttttgag taaatagaac aaaaaacctg cactagtttc
   115381 cgctagtaca ggcagtgact atatcggttg ataatctagc atatattaaa aataattgca
   115441 agaaaagaaa tttatagtgg tttataccaa attatcaaag caatgttatt ttgttgctgt
   115501 ctattgtttt ttaattattc acacgataac taaaggtggg tgaagagaaa tgattccatt
   115561 aataatttca atttttgcgc tctgtcttaa tgtctatatg attggattta aaaatgggca
   115621 aaataaaaaa tagtagcagc caagaataat tttatagtgt cactgtggcg gaaagggtag
   115681 acgctaagca tgtgtgctag gtcaatgctt cggcaaccat gcaaggttcg attccttgcc
   115741 agcgacatta aatgcctatg acggttacga ctaccgaaaa aagatcgtta agaagctata
   115801 cggtgctacg tacggcaatg tagtaagtgt gctatctgta caccaccaag cttcggtcac
   115861 tgtggcggaa gtagaagacg cagcggtaaa tggcgagtag cctcgtgaga gcctggtaag
   115921 ttctcgtgag tggtgcaatc ccactccagc gactttaagc aaccgaggca tcggcggttt
   115981 aaaaatatag gggtgcgcaa tttcgtacgc gttttgtgca tcgtgcaagt tactattaca
   116041 tattagatca ctctttgagt ggtcttttta tttttgcaca aaggaggaaa caacaatgta
   116101 tagaccacaa tacttagaac agaagtatga agtaatcact gttcataaag gtaatggcga
   116161 aaaagtatat gagtatagaa gaccaataaa gagcgataca tataaacgaa aggaaaacaa
   116221 tgaagttatt ccattgtatg gcaaaagaat agctaagcat taaataagat tgcgaaagga
   116281 gacggaacat gaccgaggaa ttctatagat ggctattaca gttgacaaga gaagatcgtt
   116341 tggttaagtt ctatcagtct cctaaatggc gcaggcttag agagaaagcg atgaaacgag
   116401 atcactatga atgccaagag tgtagaagac taggtaagta tcatagagta gagaacgttc
   116461 atcatataaa ggaagtcaag gatagacctg acttagcttt agatttagat aatcttattt
   116521 gtttatgtgt tgaacatcat aatgaagttc atggcagata tcttacagca ttagataaac
   116581 aagagaagaa gatagaaagc tttgctaact tcgatgcaag tgaaaggtgg taagtgcatg
   116641 atcatcaatg ataatggcag agagtatgat acagaaaaga ttgaagagta ttcatcttat
   116701 actcagggat taattaaacg tttgatatac gttcgctatg taggtattag ggatctgtta
   116761 tcagataact gttgtagtaa atacaaagtg aatcaagtaa gagaagcgtt gaataaagat
   116821 aataacgtcg aaagaataaa aaatgttttt ggatatagta ttgaagagat taattattac
   116881 attgacttcg ctgaagcttt cattccgatg gtgagataac ccccccttaa aataaatcgc
   116941 aaattttttg ggggtgatga aacggagggg gctgtcagga aaagagattt tttcgaactt
   117001 tatcatgaaa ggagggctaa aatgtttaaa aacgaattgt ctcaaaatcg ctacagagaa
   117061 aaattacgcc gctctttaat aagccaattg gaaagtcaga aaacaaatat tgagccattc
   117121 ttagataatg ttgatcgtta tatcagttta tgggaaacgg cgatatcact ggaagaagat
   117181 atatccgaga acggcattag actggagaat ggtaaaaaga atgaatcagt agcgttgctt
   117241 gtttctgtca acaaacaaat gggattgatg ttggataaac ttgccattac tcctgaattg
   117301 gtaggtgaag caaatgaatc aattcctgag ttataagcat attgaaaatt ggttcaaagc
   117361 tatagaagaa ggcactatca aggtatgcaa agagcaatta ttgctaaaaa attatctaga
   117421 agaaagagtc tttactagag aagatattta cttcgataag cagatggtag aggattcaat
   117481 caatatacca gcacaatact ttccattcga attaattccg tgggaaaaat ttctacaatg
   117541 ttttatttat ggtgttcgat ggaaaaaaga taaaacacta gtgttcaata gatatctttc
   117601 attaatggga cgtggtaatg gtaaaactgg ttttgcttct tggaacaact tctttctact
   117661 aaccgctaaa cacggtatta aaaattatga tattgatatc tatgccaata atgaaagcca
   117721 agcaaagact agttttgatg atgtatttaa agtaattaaa gatcatcctg atttagataa
   117781 aaaagtattt aaagctacga aggaagttat tcaaaatatc gctacaaaca gcaaacttcg
   117841 ttataacacg gcaaatgcta gaacaaaaga tgggaagcga ccaggtgcaa accgctttga
   117901 tgaaattcac gaaaatgaag attattcaat gataaatgtg gctacttctg gtggtggtaa
   117961 aattcgagat tatagagaat tttatgatac aactaatggt catgttcgtg gtggtccgct
   118021 tgatgacatt atagaagaat caaaaatgat tctttctgga gaacttggaa ttgacaagga
   118081 tggagcagaa ttttctagtt tgtttccatt tatttgtcgc ttggataacg ataatgaagt
   118141 tgatgatccc gacatgtggg aaaaagcttg tccaactatt aattacaatg cagatttaaa
   118201 acggaaaatg tttcaagaat actctcaaat gcaacgtaat gctggtttaa gacttacgtt
   118261 catgaccaaa cgaatgaaca gacctatgga agatacacga tttgctgttg cttcatatga
   118321 tgatgttctg catacgaaag aaaaagaatt tcctgaaaaa atggatgaag tgataggaac
   118381 agtcgatttt gctgatagac gagattttgc cagcgttggg ttgctaggaa aatacgataa
   118441 agatgtttat tttacacaac atacttttat ccacgaatca gcccttcgat tacaaaacat
   118501 caaacgagag gttatagata tttctataga tcaaggaaaa tcacagatcg ttcatggaaa
   118561 aaatatagaa gctgattata ttgtaggttg gtttcttgaa atgagtaata aatattatat
   118621 taaaaaaatc gctatggata tgtaccgtgc aaaaatattg aagcccgctt tagaagaagc
   118681 aggttttact gtggaaattg ttcgaagcgg atctgttaca catggtatgt taaaagatct
   118741 ggttgatgac ctttttatta atcaacgttt attttttggt gacgatgcga ttatgcgttg
   118801 gtattgcatg aatgtatatg aagagcatat ttctaatgga aatatacgct atgaaaaaat
   118861 agaacctgaa actagaaaaa cggatggctt tttttcattc cttcatggtt tgaatttttt
   118921 agatgatatt tatgattctg ctcctgtaac agtcacaaat agctcagtag aaaatacagg
   118981 aactggattt actcctctag tattctaact tgaaaggagg tgagaaagtg gggatttttc
   119041 aaaaggcggt aggatacttc acaaaaaaag caacggttcc tttagaagaa tacttttgta
   119101 aattgcaagt tgattttgtg tatcgaaaat ttgcgattga aacttgtatt gatttgattg
   119161 caaatgcgat gagtaaagcg gaattcaagt catatgaaga tggaaaaaat aaaaagaatg
   119221 atctttacta taggctgaat gtagctccta ataagaaaaa taatgcaaca gaatttagaa
   119281 aaaaactgat caggagatta atattctaca atgaagtatt gatcgtttct ccgtctaata
   119341 attctagcga aatatttatt gcggatagtt gggatgtcac agaatatgca ttgaaagatg
   119401 atgtgttttc tcaagtgcaa attaacaaca tagtccttga tagagaattt ctagaaagtg
   119461 atgttatcta tataaaatac gcagatcaac aaattaggca actagtcgat gcgtattatc
   119521 aagcgtatgg gaaactcatt tctagtgcca tgaatgttta caagcgctct aacgctcgta
   119581 gatacgtact gaaagggaat ttattccgac cgcaagacaa tacaacacaa gatcaaatca
   119641 ataaaatgat gacatcacaa tttaaggctt ttatggaagc tgataatgca ggtgcggtat
   119701 ttcaattaca aaatgagtac acattagaag atttcagcgg aaacttccaa agcaattcaa
   119761 gagatataaa aaacttaata gacgacatct ttgagatgac agcagcagcg tttcacgttc
   119821 cgaaaaacct actaaaggga gacatgagtg ggttatcgga tcaagtggac gcttttttaa
   119881 tgttcgaaat cataccgatt gctgaactta ttcaggatgc gtttaacgct agtctctatg
   119941 aagtagaaga atacttgtca gggaattttg tacgtgtgga tacaactatg atcaagatta
   120001 ctagcttcaa agatttggtt gacgctattg atgtaggcat tagaaatgga gtatttacaa
   120061 tcaacgaagg aagagaacgc gttggaaatg atcgctctga taaggcgatg gcagatgaaa
   120121 tatttataac taaaaacaat caacaagtat cgaaaggagg tgaggcgaat gacgacaatg
   120181 aaaacatttc tagcagtaaa gaatgaaggc gcagtaccgc aaatttttat tcagggattt
   120241 attggttcta gttggttctt tgaagggaat actgacaagg gaatcaaaaa tattttggat
   120301 agtctaggtg atcaagaaga aattgaagta gtaattaatt caaacggtgg agacgtattt
   120361 caagggattg ctattgggaa cttacttaag tcaaataaag caaaagttaa cgttgtgatt
   120421 aacggcttag ccgctagtgc tgcttcaatt atcgcaatgg ctggcgatac tataaaaatc
   120481 tacaacaatg cacaattgat gattcaccgc gcttccacat acggagaagg aaatgtcgat
   120541 gacttccgta cgattgctga ccaactggaa tcaattgata aatcggtaaa ggcttcatat
   120601 aaaacacgat tcaatggcac agatgaagca ttgcaagaac ttcttgaaaa agaatcgttt
   120661 atggatgcag aaacagcttt gagttatgga ttggtcgatg aaattatcga tgcagaaaat
   120721 agctcaggta ctgaagctaa aaaagaacaa agcgttgaag aaattttgaa tgacgttaaa
   120781 gaaaaaagag cagaaaaaat tgctgcattt acagcagcat taaataaaac atttggacaa
   120841 ggagatgtaa aataatgaca gttaaaaatt taaaaggtgt aacagctgca agcgaccaat
   120901 tgatgaaagc ttttaaagat ggtaacgaag aatcttttag cgcagctatg gtaagcttat
   120961 ctaaggaaat tcaggataaa attttagaag aagcaacagc aaaaaatcaa gatcaattag
   121021 tattaatgaa ccgtggtcag cgtgtattaa ctacacaaga aacaaaattc tataacgaag
   121081 tagtgaaaaa cgaaggtttt gcaggggtcg aagaattagt gccagctact gtatttgaac
   121141 gtgtatttga agatttagaa caatctcatc cactattgca aaaaattact tttgttaaca
   121201 caactggtgt aacagaatgg attgtgtcac gtggagtcaa tccagcatgg tggggtaaac
   121261 tttgcgaagc tgttaaaaaa gttttagata atggctttga tgtaattaac atgaagcagt
   121321 tcaagctatc aggttatatt cctgtatgta aggcaatgct tgatttaggt ccagtatggt
   121381 tagatcgtta tgtccgtact gttttagtag aatcattgag aattgcatta gaacaagcaa
   121441 ttgttgatgg tactggtaaa gatatgccag tcggaatgat gcgtgacatg agcaaacaaa
   121501 ctagcggaga atatgctgaa aaaaaagcag aacctattac agctttagat gctgtaacta
   121561 tgggcggttt gatggcgcga ctatcaaaat tcaatatcga aggtgtgaat gatccgattt
   121621 atcgtaatgt gaatccttct gatgtggtcc taattgtgaa tccaactgat tactggtcta
   121681 aagtattccc agctaagact gtactaactg ctaatggaga atacgtacaa gtattgccag
   121741 taccagtttc agatttgcag tcaacggctg tgccagaagg aaaagcagtt attggggtag
   121801 cctcagatta cttcatgggt gtaggatcta cactaaaaat tgaagcttca gatgaatacc
   121861 attttgttga agacgaacgc atttatctag ctaaacaata tgcaaacggt caacctaaac
   121921 gtaacgatag tttcattgta ttagatatta gcgctttggg aactactact acaactacaa
   121981 aaccaacaac cacaacaact acaacacaag cgtaggtgat cagaatgaag tatattcttt
   122041 gtcagccggc aatcaatcgg tttaaatggg agcttgaagt ttgtttaact aatctgaaga
   122101 aactaggaat caaagatatc gtattgcttt tcagcagaca cgatgatcag attcctattt
   122161 tttttgagaa ggaatatggt gttgaagttc atgtgtacga tgatctgcgg gacgacaaag
   122221 agtatattcc ttcgattaaa ccatatttat ggtggaaata tttagaagaa gatcattcgc
   122281 gtgaggacga ccgatatttc tatatcgatt cggatgtcat tttcaataaa agaattaatt
   122341 tgcgcaaatt gccttctaaa gatgatgttt ggtattgtag cgactgctgt agttatctaa
   122401 gtcttgatta tattagaagc tgtgaaaacg gagaaaatat tctaaaagat atggcaaaca
   122461 ttgtaaatgt tacagtagaa tctttggaaa ctataaacac taattcagga ggcgcacagt
   122521 gggttattaa ccgtcctaaa gcgaattatt ggaaaaaggt ttatctggat tctaatcggc
   122581 tatatcgcta ccttagaggg caaaaaacaa atatacaaat ctggacagcc gagatgtggg
   122641 cacagctttg gaacatgatg tatttcaata ttggtcctaa agttcacgag gaattagact
   122701 tttgttttgc tactgatcca atagaaaaag ttaaagaagt aaaaatctta cacaatgctg
   122761 gagtaacaac aaacgatgaa gatttatttt tcaaagggag atacgtgact tctacgcctt
   122821 ttgatgaaga tttatcattt gtaaacaaga aaaaatgctc ttacgcatat gttaaagcaa
   122881 ttaaggcggt ggttagatga cgcctgaaca agtgactgaa gaattgctaa tagctgtgaa
   122941 ggataatatt tacgttacct ggaacgaaga agatgagtca attaaaaaga tgatagctaa
   123001 aaatgctgtt tatcttcaaa gtaaagtgag tacaacactt tctttttctc ctgaaagctt
   123061 agaatacgga ttgctaatcg aaagatgtag atacgactgg aatcgtgctt tagatgagtt
   123121 tgaacaaaat ttcgctagtg agttattagg tttcattcaa cattatgcgc tacaagaata
   123181 tattgcaggt gatgtgaatg gcgaataatc gtagactcga agaaacattc aacgatggtt
   123241 ggttaaagat tttgacgcaa actaccaaaa gaaatgaact aggaaaaaag attggtgtag
   123301 aagatacaga aatcacttct ttaaaattta gaaatctttc catgagagat agtgatataa
   123361 cagctatgga tgcgatggga tcgaaattaa ctaagaaagt aaagactcca tttcatccaa
   123421 tcgccaagaa atttaataaa gatcaatatt ttatcgtaat cgatagtatg cgttacaacg
   123481 ttatctatgc cgattacgat aatttttata tctattttta tcttgaaagt gtgggtgaat
   123541 atggtgattg ataattctaa agaaaaagaa cgtttaaata agcaaatttc tgctatcaaa
   123601 acttccttag aagagcattt tggcctcaaa ctctttcaag actccgtagg cgaggatgag
   123661 ctacctgatg attttaatta cttcattctc gaaacaggag aaatagaaat gatcactgag
   123721 ccaaaatata gcgtgggtca aaatctatat ctaactttct attcagaaaa tagagaagat
   123781 ttaacaggag actcactaga tattatttca ttgattcaaa atcgttcgat tcgttttcag
   123841 agaatggatc ccaatcattt aaaactagag aaccaagatc gctatatcga tcaattggta
   123901 tttacgttta gacgattatt gaagagtgat tgtcatggct aaaaatagtt gggagctaaa
   123961 aataaatgga catgatgaac ttcttgtgcg gatggaacgc tattcaagcg agagcgaacg
   124021 actgattaac gaagcattga aatcaaaagg ttcggctatt gcagtggata ggattacaga
   124081 aaaaattcct gtttctgaag cagatttaag aagagggcac caacacgcaa aaaatagtcg
   124141 tccacttaag actcaataca ttaatttggg tttcatcatt agacctacaa gaaaatttga
   124201 gtatttaaaa tatcctgatt tggggatagg tacttctaaa agaaatcagc cggacgaatt
   124261 tatgagaaga ggattaggtc ttgcacttga tccaattaca gaacttctga ttcgtcaatt
   124321 cgataaatta aataaatagg gggaacaaca atggctaaaa caaaaactgt agtaacaacg
   124381 ttcgataacg taagtatcaa acgaattgct tttaatttta agaacgcagg aaatgcaatc
   124441 gcaacgaatt gtaatggaca attagatggc gaaacagaaa tgcaaacggt ggttaaaaaa
   124501 tgtggagcga cagaagtaaa atcaaaatct aaaccaatca atatgacggt aacaattact
   124561 gcacatgtac cgatggaagt ttatcgacgt ttcaatgggt tgaaacaaga tggacgtatt
   124621 aaaccaggca tttactctta cggtcctgat tccgtaggcg aagatttctc acttgctgca
   124681 gagatcgtgg atgacttcga agaaaataga aagttagttg gtatgttagc atgcacttcg
   124741 aatacaggat taacattctc tattgaaaat ggtgcggatg aagtagctgc gttagaacta
   124801 gaaacaaaag ttatgcaaga tgaatttggt aaattttatc atgaagcaat tgttgcagaa
   124861 cttgaagaag acttaacaga tcaatggatg acgaatctat ctgctgatgt gattaaaaaa
   124921 acttcagttg tgacaactac ggccactcaa tcacagtaaa aaaaacggag gtagcgaaat
   124981 gaacgaagat tactcaaaaa ttgaactaaa cgatggaaca attttgaatt tagaacctaa
   125041 actgaatatc aagaaattat tgatgatcaa tagagatttt aacacagacg agtttgcaaa
   125101 aatgactgtg ggaaaaggat ccatggatat ttctgttatt caaggtgcaa aggctgtgta
   125161 tattgcttac cgccaagcga acatgactga ttatatttca ttcgatgaat ttatcgataa
   125221 atgggatttt gatatggcta ctgccagcta tatttatcaa ttgatgatgt tcaaacaagc
   125281 acgcgatgct tatcaaaaag aatttgaaaa agcaaataag gaaaaaaagc ttcaaaagta
   125341 aaaattccaa agctcttagt tgaaacgtgg gtcgatgtct attcgatgtt gaccgacgtt
   125401 ttttctatgc cttcagattt ggttttaagc gatatctgtt tagatgacat tttgcaaatg
   125461 gcttacaaca agagtgctta tgaaggatgg aaaaactatg caataaacca atcccagaaa
   125521 aactaaagaa aggaggtaaa aaatggctaa aaagagaaca gaagcagaag taactttcat
   125581 agctaacgat gacggattga aatctacgtt aaaagaaatc agtgctgaat taactaaaaa
   125641 tagagcagaa ttaaaactag aacaagctca attacaacag actggttctg aatcagacaa
   125701 gttaggaagt aaattatctt ctttagaaaa gcagtatgaa ttacaaagtc aaaaagttga
   125761 agtaactagc caacgtttag ccaatgcgaa aaaatattat ggagaaaatt ccaccgaagt
   125821 tcagaaactt gaaagagaac tgattaatca acaaacagcg caacaacgtt tgtcaaacga
   125881 aattgataaa acgagtaatg cactagctca agcaaaaggc gaaatacaga cgtacgagtc
   125941 tacaatgcaa cagttggata gcgaacaaaa aaatgttcaa gctagtgctt ctctgattga
   126001 atccgaatac aaaaaatggc aagcaactgc tggtcaatca gcttctgaag ccgagaaatt
   126061 agcgaaagcc caagaatatg tttctcaaca atctgaaaat gcggagaaaa cgatagatat
   126121 cctaagacga cagttagaag ctacacagtc tgaatttggc gctacatcca cagaagcaat
   126181 gcagatggaa gcgaagctta atgatgctga acgtgaattt gaagagttag gacaagctgc
   126241 taaaaatgta gatacaacta acttggacga tatcggaagc aaaatagata tgaataattt
   126301 aatggaagct tctgacgttt taagcgacat tggcgataag cttacagaat tagggaaaca
   126361 agcagtggac tctgctaaca gtgtaggtag ttcccagagt aagatacaag ctaattttgg
   126421 tttgtctaaa caagaggctg aagaattaac gaatgtagcc agagacattt attataaagg
   126481 ttttggagaa tcgttagatc agtccacaga tgcattgatt ttggtaaagc gtaatttagg
   126541 agatttaaat aatcaagatt tacaaaatat cacggaacaa gctatggtcc tagaaaacac
   126601 catgggcgct gatatggatg aaacgttacg tggtgtaaat ggcttaatgg tcaatttcgg
   126661 cttgagtgct caagatgcaa tggatttaat ggtttcgggt actcaaaacg gtttagataa
   126721 aacgcacgaa ttaggcgaca atatggcaga atatagccaa ttatggagtc aaatgggata
   126781 ttcagctgat gaaacgttcg gaatgcttca aaatggttta gatgcgggtg cttataacct
   126841 tgataaagtc aatgacttag ttaaggaaat gggaatatcg ttaacagatg gtcgatttga
   126901 gcaaaacatg gatatgttta gtgaaagtac tagaaaagct tttgaagagt ggaaaaatgg
   126961 cggaggaaca caaaaagacg ttattaattc catgattcaa gattttagca atatggatgg
   127021 tcaatacgac caattaaata aagcttcgac aatttggtct gcgcttggcg aagataatgc
   127081 gatgaaagtt gtccaatctt taactgatgt taaccataca tttgatgatg ttagtggatc
   127141 tgcacaaaaa atgaatgaag attctactac tccgttgcaa gagttgaacg ggaaaatagc
   127201 tgaattaaag gattcattag ctcctatagg caacacaatc atagatgcac tcgaaccagt
   127261 aattgatttt ctaggaaaga tggctgatgc gtttaataat cttccacaac cagtacagga
   127321 tttcattgtt gctataggtg gtcttacagc agcatttggc atactgttac cggcaatact
   127381 agccgtgtca tatttatttg gtccgatgat gcttataatt ggaggaatta tagctgttat
   127441 agcaggcgtt attgtggcaa ttaagaactg gggtgcaatt actgactggt ttagtggttt
   127501 atggaaaaaa tttactgatt ggttgggtga tacttgggaa agtataaaag acggagcctc
   127561 atcagtttgg gatggggtta aagaaacctg gtctggattt gtagattggg ttcaagatat
   127621 ttggcaagga gtttctgatt ggtttggaga gctatggagc ggattagttg aaggagcttc
   127681 caacatctgg caaggagtcc aagaaacttg gcaaacattc gttgattggg tttcaaatat
   127741 ttggaacgga gtcaaagaag tatggtcgat tatttgggca gacattgtag gaattgttca
   127801 aataccatgg acattaataa cgtcattgat tcaagctggt attaatatta tcgtgggtat
   127861 ttttgatgta gctggacagt tattgggcgc agcttggcaa gctgtttgga cacctatttc
   127921 tgatttcctt aaaaatactt gggatactat gacacaatgg ataagtatcg cttggaatgg
   127981 gattgtaact acattccata ctatatttga tccagtagtg gcatggtgga atggtatatg
   128041 gacagctatt agtactacgg cttcaaatat ttggaattca attagtgcaa cagcttctag
   128101 tatttggaac agtatcaaga atacaatcac tagcttggta caagcagctg ctacagtaat
   128161 tcaaaatatt tggtcaactg tatctagttg gttaggtgga atttggaatt caatcagctc
   128221 tacagcatca aatatctgga atagtgtgac tagtagtata agcaatgcta taaacgcagc
   128281 taaaagtgcc attcaaagtg tttggaatag tatatcttcg tggattagcg gaatttggaa
   128341 cggtatcaaa aatactgctt tgaatctttg gaatggaatt acaagcacta ttagctctaa
   128401 agtaaacgat ggaaaaaatg caatttcaag cggttggtcc aatctaacag gtattgtttc
   128461 cgacatattc aataatgtta aaagtacaat tgctaacata tgggaaggca tcaaaaagac
   128521 tgttagcgct ccaattgatt ggattagaga caaaatcagt ggcatttttg ataatttgaa
   128581 tatttctata ccacatattc cgttaccgga atttatcatg gaaggcagct ttaacccgct
   128641 aaaaggtcaa atcccccatt tgcgtgtaaa atggcatgct aaaggaggta tctttactaa
   128701 accaacttta ctaggtggaa tgaacggtgt cggtgaagca ggacctgaag cagttttacc
   128761 tttgaaaaga tctgttttgc aagaaattgg tgatcgtatc ttgagtagca catcagtttc
   128821 atctagggca caaacgattc aacctgtgaa taactacgaa ttcaatttca caattgatgg
   128881 taacgcagat gaggttacta tgaagcaaac aactcaacaa atcattgata gcattacaaa
   128941 aattcaaaat gataatgctt cggcatggcg ttaaacagga gagtatttct cctgtttttt
   129001 tagtattaaa aaggatgtga aaaaatgact gattgtatac attctataat cgatggattt
   129061 cctgattatt tgcataaatt ggctttagct gaaagaccaa ccataccttc tccaaaaaga
   129121 cagagagttg aaacttctgt tttaggtagg ttaggtggct tagtacaaga ttactcgttt
   129181 gaagatatgt cgtttacatt gcactataac tatttagagg atgtggaaga ccatcaagcg
   129241 ttcaagcaat cgttttatat catgcgtcat tggttaaact atgcaaagaa attagaattc
   129301 tctgacgatc ccaacgtcta ttacgttatc cagactatcg atattgggga tgcagaaaac
   129361 gatattgttg aatggggaga gttcgatgta aatattactg cgaaaccatt cgcaagagtt
   129421 caagaagatg tacctataac cgtagataaa ccacagtcat ttaacttgct gaataatagt
   129481 ttagaagaaa gttttccaaa gattatcatc actccttcag ctacttcatg ccagttcatc
   129541 ttaaatgatt atgtgtttag tttcgaaggc ttagtagcag gaactgatgt agtcattgat
   129601 agtgatttga tgctttgcta cgaagagcaa tcggacggag atattttaga tcggtccaac
   129661 aaaatgaaga ccatgcaata tccgacattg caagtggata tcaatcattt taattgcact
   129721 ggtttgagca aaatacaaat ttatcgtaac gggttaaggt aggtgaaata gatgatcgat
   129781 aatttaataa ctatttacga taaaaatgac gcgaataatt tagctgaaca tttatatgat
   129841 acgcaaggtt taggcgcttt gtcagactgg ttaacagcta ctgttagcaa taaactaaac
   129901 ggagccgaga tatttcaggg tacttattca ataaacggaa ctaatgcaga tttgattgta
   129961 gacggacgta ttattcagtg ttatgtagat gaaaatcgag caaaacagcg tctacggatt
   130021 tattatgcaa aaacttctgt aataggcaat acgatagaag taaaagctga acctattttc
   130081 aatgatataa gaaaatcggt gttgaataaa tatgacagcg gaacagaaaa gatcactgct
   130141 actcaggcat ggcaaaacgc aaaagtttta gcgaaaccag ctatcccttc gcagttttct
   130201 ttctcgtcat tagtagatac gcttgctaat gtgaagatag aaaaggcgaa ttttttagaa
   130261 ttctttggtg gaaaagaggg atctattcta gatcgatttc atggtgagtt tctaaaagat
   130321 aataacacat tacgtcatga aaaaagtcta ggtacggatc ataaaatcaa agcgatttat
   130381 actaaaaact taactggtct tgacttagag attgatgctc aaagtgtttt agttggagtt
   130441 tatccattca ttagcagctc ttcagaagga gaagacgaga tcactctacc agaagaagtt
   130501 attttcacgg attacgtgga tgattatcct gctggatatg tttcttttgt tgattttaaa
   130561 gacaaagcga ctgatgtagc cacattaagg gaagctgcta aagactggtt gaaaacaaac
   130621 atagataaac aaaaaccaca agtgagtggt tcgattgaat tagtaccatt gaggcatcaa
   130681 agaggctatg aaaaatttgt tgatctagaa aaagtttcga tgggtgacgg agtagatgtg
   130741 tatcatccac agttaaaagt gaatatgtca gcgagaattg tggaatatac gtttaatgtt
   130801 ctaaccaatt catacgataa attagttgta ggaaacgtca aaacaaactt cttagaaaac
   130861 acagagaata atgtcagcaa tttgattaat gatgccattg atcaattgaa aaacggtggc
   130921 gaaatcagtg atttactcaa tgatattgta gatcatcaaa ctgatatgat tactggtcaa
   130981 aatggtggtt atgttttatt agatcctaaa gaagcgccta gtcgtatttt gattatggac
   131041 acaccagata agaataccgc aaggaatgtt ttacaaatca acaatgctgg tattggtttt
   131101 tctaaaactg gcattaatgg aacatatgaa acggcatgga cgttagatgg cggattcaat
   131161 gcctcgttta ttacggctgg tgaaatagta ggaattacta ttagaggtac tacattaatt
   131221 agtgatggtg ctgattatag aacaagtatt gctaatggca aaatgacttg gtactcaaaa
   131281 aaagttaaca aagatattat ggagctagaa gcacgtgatt atgtaagtgc tgatgccggt
   131341 attgtatcat acaccatgaa aactggtggt ggtttcatga ttagaaatcc acagggtaac
   131401 ttggttttta gtacgtggga taatggtaat aacagaccgt ttctatcttt tggtgcgccc
   131461 aatttcaggt atagcaatgc tagttatgta acttctggcg acggtagttc tttaagcatt
   131521 aatggtagtg cgggtaactc atgggaattt aaggtagctg gtaggactat gaaatttact
   131581 agtgatggta tgctaacgtt accaggttgt ttttttggtt catgggaaga tgggaaactt
   131641 gctaggtttg aacaatcaac ggtacaagta tataaagatt ttactgttag aggtactaaa
   131701 aactcaactg taccaacaga acattatgga caacgactat tgaacgctta tgaaactcca
   131761 gaatattatt tcgctgatta tggggaagcc gttacaggtg acaatggtaa agttcgtgtt
   131821 gatattgacc ccatgtttgc tgaaacagta aatctaagtc ggtatatgac acatgtgaca
   131881 cctacagaac tagttttgtg tgctgttact catgaagata ttgaccattt catcattgaa
   131941 actagtaagc caaacgtatt agttagatgg aatttagtgg cacaccgtct agggtatgaa
   132001 gatattagat taaaagagga tacagcatat gatagcacag tgcttgacca aaaacgtttt
   132061 taaaacgaag acaaggaggt atataaatgg ctagcagttt atataatttg gctttagatt
   132121 tcagcaaaga attaaactac accaaagcta ttatggctcg tcaaggtgat aaagggatta
   132181 cggtgacggt taaaccgttt ctaaatggct tgcagatgga tacgagtggc ggaacattta
   132241 ctttaaaagg aacaacacca tctaaccgtt acgtagataa tgttgcaact agtgtaacta
   132301 gtgaagaagt cacgttttct cttgatggca catttatgag tgaagcagga tattataaac
   132361 actgctacgt agaatataga aaagacaatc aaattttaac aacgcaagat atcatttttt
   132421 tctcactagg agtgtctgac atttcgcaag gccaagccga tgaatatgtt tcgcaattag
   132481 aagagttgat tcgaaagtac aacgaaactt ttgatgcttt tatggctgaa atcaaaggta
   132541 gagtggatag cttaaatcaa cagattactg atttaactgg tcaagctaaa acgctacaag
   132601 acaagttaga tgctctgaaa gaagaaattt ctaagttagg taacttacaa gtgatgtaca
   132661 gtaacagcat cgacttcggg gactatgatt attcggagaa cccgaattta atgccatata
   132721 ttacagaacc ttgggttgga cctttgttag gtaatggaca tacagttaaa gatagtgtta
   132781 aaagggttat aactcatact aaaactagaa cagctaattc cggcgacata ttatcgcttg
   132841 gcttaggtat tccgtgtaca gcggaagcta ataataggta tcttataacc actttacgac
   132901 catctacgac atacacatta agcgttacta tgagtgtcgg ttcagattgg actggagaga
   132961 ccaatactat aggggttagg cttagatatt taaatgaaca aggtggtata gaactgccca
   133021 ttaatgcatt aataccagca aatgtagaac gcgataaaat ggtcactcat acatttactg
   133081 gtataacaaa agataatgta actagcataa caaactgtta tgttgaaata ttctcactta
   133141 atagtgaata taaaggaacg gttagtgtca gctatgacgt taagttaaaa gcacactacc
   133201 ctaacttact agatggccct tactggttag gtaaagttcc tttaggcgag aatattgctg
   133261 accctacagt tgtctttcca cacaaaacta gtgaatatat ggtttatggt agacgcaata
   133321 cagaaaacta tatcgctgac caaacatata ccatatcaat gaaagcaact aaactaacag
   133381 ttcaatcgtt tgccgtgtat attgctgctg gccgcgttaa agtaggagac atgaagccta
   133441 ctgaggggtt agctaataca tgggagttaa cttttactgt aactaagcaa catatagata
   133501 gtggggtaac taattatctg gaaatatacc aatacccgtc agctacaaaa ggagctgttc
   133561 aaattgagtg gctcaaacta gaaaaaggca atactcgaac cccgaatatt agtgagtata
   133621 aatatcgtgg tactggtatg cgtgattcaa acaatccaaa agattatgtt tgggatctag
   133681 caccagaata tgtcgaagat aatttggcca cagatattaa aatttctgaa attactggta
   133741 aagcaaacaa ttataccgat gggaaagtat cggagattaa ttcgcagttg actgcttcaa
   133801 ttaatgaagt agacaccaca gctaaggatg ctcaaacaaa agcgaatgct aatgcgactg
   133861 ctatagatga attagacaat aagatcgatg aacgcattaa tgatacagct actaccacat
   133921 taacagttac aaacgggaat accggatcag caaagcttta tcgtgaagga aaaacagttt
   133981 ctatatattt tgtggcttta aacggaaaaa gcagtggtgg aaatgattca acgatactaa
   134041 caattccaga aggctatcgg ccaccaatta gttttgagca actggttggc tcgatagacc
   134101 gttctacttt gaacagtgct cagttatcta ttggtgcaga tggagccatt aaatggcgaa
   134161 gaaactcaag ttatggatcg gattatacct ttgcaattac ttacacgatt tagaaaagcg
   134221 tgaatcgata tgaaggcagc atatagacca attgaacctt acggattcga gcaaatcatt
   134281 gtgaatgatg aagaacattt accggaagaa tgcacagaag tcgaaccacc gattccaaat
   134341 tggaaaccga aattcaatta ctgggaggga aataaatgaa aaacatttgg aaatatggac
   134401 gtactggcgg agagtacgca ggaaaagtat tggacgacat gcttgtatcc gttccttaca
   134461 cagatcagcc accgcttgaa ggaattcgtg ctgatggcga accgttaaca atcgctgatc
   134521 aaatgtttga tcctaaattg aatcaatgga ttattttagc gaacgcacta gatcacaacg
   134581 atttaaacaa tctcaaagca atgtatgagt cgttagaaaa tgagaacggc gatttaaaac
   134641 agatcaatgc caaactcatg ctaagcgatg tagcaattaa acaggaaaat actgcattga
   134701 aagaaaaagc ggatagttta gcacaaatca attcaaaaat gatgcttgct tcgttacaaa
   134761 atagcaaaga catttcagaa attaaagagc aactaaatcc agcttcaaag ggaggtgagt
   134821 agtatgttta gttttagcga tgtgaaaatg atgtatgatt ggggctgttt cactaacgaa
   134881 caagtaatgg ttttcgttcc gttgtgcatt actgaagaaa aagcagataa aatcattagc
   134941 aaagaagaga gcgcatctta attgatgtgc tttttatttt gattcaagga gttgtcacat
   135001 gattaattta ggggaatggg gagcgatagc aggatcaata accgctatcg tttctttgat
   135061 tttattagta ataaaaccaa ttactgcatc tttctcgaag attactgaga ctctttcaaa
   135121 agtaagtcac aatttagatt tgctgactaa agatttagaa tcgagcaaat cagatcgatt
   135181 gatgattcat gaagaactaa agaaacacga tgaaagatta gatacacatg cagaaaaatt
   135241 ggtagaacac acgcaacaaa ttaaaacttt atttagggag agaagaaaat gaataataaa
   135301 acgttcgaag tactaaaatg gttcgcactg gtaattattc ccgcactagc tactttcgtg
   135361 gggttagttg gtaaagcgct caattggcag tacacagata tctgtgttgt catcattact
   135421 ggttttggcg cgtttttagg gagtgtgttg ggtgtatcaa atcgaaccta caaaatgttc
   135481 tcggctgaaa gcgaagaagg aggaaacaaa tgaaaaagaa aattactatt actgcgatga
   135541 gcctgttaac ggctcttttt ttattaccca ttaatacgtt tgcttatact attaatgacg
   135601 agtataattt agcgccgaat caaggagact ccagattagc aattcctaac aaaattattt
   135661 tgcacgaaac tggaatagat gcaccagcaa gaaacgtagc cgccaacatg aaaaataatt
   135721 ataacggaag caattcttat actacagatg ttattggtga cggtgggatt gtttaccgtg
   135781 tgggtgagca aggatatgtt tcgtggggag ctggtaacgc taatccttat gcgcctgtac
   135841 agattgaatt acagcgcaca tatgataaag cattgtttga aaaaaactat cgagcttata
   135901 ttgaatatac aagagatagt gcaaaaaaat atggaattcc attgactctt gatcaaggaa
   135961 cttctttatt tacaaaagga atcatttctc atttgtgggt gacaaattat gtttggggga
   136021 accacacaga tccatatggt tacttatcgc aaatgggagt tagcaaagaa aagcttgctt
   136081 atgatttagc tcatggattt accgatgaaa atccaacaac ttctgaaaac aagcctgtca
   136141 ttgatccaac acgagctggt gcagctaatc ctacgctgac agatggaaca aatcacgccc
   136201 acattgatca gtttggggaa atcgaaaacg caaacttgca tgtggctgga tggcacattg
   136261 ctaactataa atacgagtat attttcatta tggactacaa tactgggaaa gaattagctc
   136321 gagtaagagc tgatggaatt tatagaccag atgtaaacca agcttataat acttctggaa
   136381 atgttggtta tcatgtatct ttcaatatgc gtaattttcc tagtaagaaa gtctatgtaa
   136441 tgatgcgggc aacgaatgat ccagagggaa acactaaagg cggtgcgcaa gatttccatg
   136501 acaaacgttg gtatttaaat attcctaaac gataaaaata gctcctcgtt gaggagcagt
   136561 acataactat attgacaact ataaaaatta ttcgataaaa tagtgatgtt atcgcatatc
   136621 ttcactatca cccat
//
LOCUS       DBGZHO010000003        99755 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.003, whole genome shotgun sequence.
ACCESSION   DBGZHO010000003 DBGZHO010000000
VERSION     DBGZHO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 99755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.003"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(55..498)
                     /locus_tag="ACN3HL_000306"
     CDS             complement(55..498)
                     /locus_tag="ACN3HL_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HHC8005218.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            632..1003
                     /locus_tag="ACN3HL_000307"
     CDS             632..1003
                     /locus_tag="ACN3HL_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8005219.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            complement(1172..1954)
                     /locus_tag="ACN3HL_000308"
     CDS             complement(1172..1954)
                     /locus_tag="ACN3HL_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HHC8005220.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(1951..2922)
                     /locus_tag="ACN3HL_000309"
     CDS             complement(1951..2922)
                     /locus_tag="ACN3HL_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HHC8005221.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            3014..4408
                     /locus_tag="ACN3HL_000310"
     CDS             3014..4408
                     /locus_tag="ACN3HL_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHC8005222.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            complement(4600..5955)
                     /locus_tag="ACN3HL_000311"
     CDS             complement(4600..5955)
                     /locus_tag="ACN3HL_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HHC8005223.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(5985..6620)
                     /locus_tag="ACN3HL_000312"
     CDS             complement(5985..6620)
                     /locus_tag="ACN3HL_000312"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HHC8005224.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            complement(6627..8003)
                     /locus_tag="ACN3HL_000313"
     CDS             complement(6627..8003)
                     /locus_tag="ACN3HL_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HHC8005225.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            complement(7996..9777)
                     /locus_tag="ACN3HL_000314"
     CDS             complement(7996..9777)
                     /locus_tag="ACN3HL_000314"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HHC8005226.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            complement(9799..10110)
                     /locus_tag="ACN3HL_000315"
     CDS             complement(9799..10110)
                     /locus_tag="ACN3HL_000315"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HHC8005227.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            complement(10100..11086)
                     /locus_tag="ACN3HL_000316"
     CDS             complement(10100..11086)
                     /locus_tag="ACN3HL_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HHC8005228.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            complement(11101..11685)
                     /locus_tag="ACN3HL_000317"
     CDS             complement(11101..11685)
                     /locus_tag="ACN3HL_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HHC8005229.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            complement(11706..12176)
                     /locus_tag="ACN3HL_000318"
     CDS             complement(11706..12176)
                     /locus_tag="ACN3HL_000318"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HHC8005230.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            complement(12195..14198)
                     /locus_tag="ACN3HL_000319"
     CDS             complement(12195..14198)
                     /locus_tag="ACN3HL_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HHC8005231.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            complement(14185..14517)
                     /locus_tag="ACN3HL_000320"
     CDS             complement(14185..14517)
                     /locus_tag="ACN3HL_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005232.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     misc_feature    complement(14617..14664)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            14854..15573
                     /locus_tag="ACN3HL_000321"
     CDS             14854..15573
                     /locus_tag="ACN3HL_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HHC8005233.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            complement(15872..17770)
                     /locus_tag="ACN3HL_000322"
     CDS             complement(15872..17770)
                     /locus_tag="ACN3HL_000322"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HHC8005234.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(17933..19195)
                     /locus_tag="ACN3HL_000323"
     CDS             complement(17933..19195)
                     /locus_tag="ACN3HL_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005235.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(19188..20087)
                     /locus_tag="ACN3HL_000324"
     CDS             complement(19188..20087)
                     /locus_tag="ACN3HL_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005236.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(20232..22010)
                     /gene="uvrC"
                     /locus_tag="ACN3HL_000325"
     CDS             complement(20232..22010)
                     /gene="uvrC"
                     /locus_tag="ACN3HL_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HHC8005237.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(22192..22506)
                     /gene="trxA"
                     /locus_tag="ACN3HL_000326"
     CDS             complement(22192..22506)
                     /gene="trxA"
                     /locus_tag="ACN3HL_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HHC8005238.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(22593..24953)
                     /locus_tag="ACN3HL_000327"
     CDS             complement(22593..24953)
                     /locus_tag="ACN3HL_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HHC8005239.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(25068..25615)
                     /locus_tag="ACN3HL_000328"
                     /pseudo
     CDS             complement(25068..25615)
                     /locus_tag="ACN3HL_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            complement(25673..26110)
                     /gene="zapA"
                     /locus_tag="ACN3HL_000329"
     CDS             complement(25673..26110)
                     /gene="zapA"
                     /locus_tag="ACN3HL_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HHC8005240.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            26312..27229
                     /gene="rnhC"
                     /locus_tag="ACN3HL_000330"
     CDS             26312..27229
                     /gene="rnhC"
                     /locus_tag="ACN3HL_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HHC8005241.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(27485..28396)
                     /locus_tag="ACN3HL_000331"
     CDS             complement(27485..28396)
                     /locus_tag="ACN3HL_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHC8005242.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(28799..29377)
                     /locus_tag="ACN3HL_000332"
     CDS             complement(28799..29377)
                     /locus_tag="ACN3HL_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8005243.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(29397..30065)
                     /locus_tag="ACN3HL_000333"
     CDS             complement(29397..30065)
                     /locus_tag="ACN3HL_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005244.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(30080..31150)
                     /locus_tag="ACN3HL_000334"
     CDS             complement(30080..31150)
                     /locus_tag="ACN3HL_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005245.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(31321..32685)
                     /locus_tag="ACN3HL_000335"
     CDS             complement(31321..32685)
                     /locus_tag="ACN3HL_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HHC8005246.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(32682..34241)
                     /locus_tag="ACN3HL_000336"
     CDS             complement(32682..34241)
                     /locus_tag="ACN3HL_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005247.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(34297..36777)
                     /locus_tag="ACN3HL_000337"
     CDS             complement(34297..36777)
                     /locus_tag="ACN3HL_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005248.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            complement(36761..37096)
                     /locus_tag="ACN3HL_000338"
     CDS             complement(36761..37096)
                     /locus_tag="ACN3HL_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005249.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(37110..38144)
                     /locus_tag="ACN3HL_000339"
     CDS             complement(37110..38144)
                     /locus_tag="ACN3HL_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HHC8005250.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(38234..38914)
                     /locus_tag="ACN3HL_000340"
     CDS             complement(38234..38914)
                     /locus_tag="ACN3HL_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HHC8005251.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(39198..40301)
                     /locus_tag="ACN3HL_000341"
     CDS             complement(39198..40301)
                     /locus_tag="ACN3HL_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HHC8005252.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(40930..41400)
                     /locus_tag="ACN3HL_000342"
     CDS             complement(40930..41400)
                     /locus_tag="ACN3HL_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HHC8005253.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            41730..43370
                     /locus_tag="ACN3HL_000343"
     CDS             41730..43370
                     /locus_tag="ACN3HL_000343"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HHC8005254.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43524..44846
                     /locus_tag="ACN3HL_000344"
     CDS             43524..44846
                     /locus_tag="ACN3HL_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HHC8005255.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(44914..45348)
                     /locus_tag="ACN3HL_000345"
     CDS             complement(44914..45348)
                     /locus_tag="ACN3HL_000345"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005256.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(45413..46249)
                     /locus_tag="ACN3HL_000346"
     CDS             complement(45413..46249)
                     /locus_tag="ACN3HL_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HHC8005257.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(46991..47617)
                     /locus_tag="ACN3HL_000347"
     CDS             complement(46991..47617)
                     /locus_tag="ACN3HL_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005258.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(47912..48247)
                     /locus_tag="ACN3HL_000348"
     CDS             complement(47912..48247)
                     /locus_tag="ACN3HL_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HHC8005259.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(48234..48518)
                     /locus_tag="ACN3HL_000349"
     CDS             complement(48234..48518)
                     /locus_tag="ACN3HL_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HHC8005260.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(48574..50097)
                     /locus_tag="ACN3HL_000350"
     CDS             complement(48574..50097)
                     /locus_tag="ACN3HL_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HHC8005261.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(50090..51265)
                     /locus_tag="ACN3HL_000351"
     CDS             complement(50090..51265)
                     /locus_tag="ACN3HL_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HHC8005262.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(51269..51454)
                     /locus_tag="ACN3HL_000352"
     CDS             complement(51269..51454)
                     /locus_tag="ACN3HL_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005263.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(51420..53114)
                     /locus_tag="ACN3HL_000353"
     CDS             complement(51420..53114)
                     /locus_tag="ACN3HL_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HHC8005264.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(53111..53584)
                     /locus_tag="ACN3HL_000354"
     CDS             complement(53111..53584)
                     /locus_tag="ACN3HL_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HHC8005265.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(53653..53808)
                     /locus_tag="ACN3HL_000355"
     CDS             complement(53653..53808)
                     /locus_tag="ACN3HL_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HHC8005266.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(53942..54322)
                     /locus_tag="ACN3HL_000356"
     CDS             complement(53942..54322)
                     /locus_tag="ACN3HL_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HHC8005267.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(54326..54541)
                     /locus_tag="ACN3HL_000357"
     CDS             complement(54326..54541)
                     /locus_tag="ACN3HL_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005268.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(54544..54951)
                     /locus_tag="ACN3HL_000358"
     CDS             complement(54544..54951)
                     /locus_tag="ACN3HL_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HHC8005269.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(55217..56692)
                     /locus_tag="ACN3HL_000359"
     CDS             complement(55217..56692)
                     /locus_tag="ACN3HL_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HHC8005270.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(56682..57530)
                     /locus_tag="ACN3HL_000360"
     CDS             complement(56682..57530)
                     /locus_tag="ACN3HL_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HHC8005271.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(57567..57929)
                     /locus_tag="ACN3HL_000361"
     CDS             complement(57567..57929)
                     /locus_tag="ACN3HL_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005272.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(57930..58088)
                     /locus_tag="ACN3HL_000362"
     CDS             complement(57930..58088)
                     /locus_tag="ACN3HL_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005273.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(58229..58853)
                     /locus_tag="ACN3HL_000363"
                     /pseudo
     CDS             complement(58229..58853)
                     /locus_tag="ACN3HL_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(58850..59161)
                     /locus_tag="ACN3HL_000364"
     CDS             complement(58850..59161)
                     /locus_tag="ACN3HL_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005274.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(59205..59498)
                     /locus_tag="ACN3HL_000365"
     CDS             complement(59205..59498)
                     /locus_tag="ACN3HL_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005275.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            59692..60339
                     /locus_tag="ACN3HL_000366"
     CDS             59692..60339
                     /locus_tag="ACN3HL_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005276.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            60400..61545
                     /locus_tag="ACN3HL_000367"
     CDS             60400..61545
                     /locus_tag="ACN3HL_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005277.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(61984..62802)
                     /locus_tag="ACN3HL_000368"
     CDS             complement(61984..62802)
                     /locus_tag="ACN3HL_000368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005278.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGNSYNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(62902..64227)
                     /locus_tag="ACN3HL_000369"
     CDS             complement(62902..64227)
                     /locus_tag="ACN3HL_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005279.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            complement(64396..65325)
                     /locus_tag="ACN3HL_000370"
     CDS             complement(64396..65325)
                     /locus_tag="ACN3HL_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005280.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            complement(65573..65887)
                     /locus_tag="ACN3HL_000371"
     CDS             complement(65573..65887)
                     /locus_tag="ACN3HL_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005281.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDRIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFREFRNQIIRSSNI
                     EN"
     gene            complement(65964..66458)
                     /locus_tag="ACN3HL_000372"
     CDS             complement(65964..66458)
                     /locus_tag="ACN3HL_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005282.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTIDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKNDTEKPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
     gene            complement(66451..66765)
                     /locus_tag="ACN3HL_000373"
     CDS             complement(66451..66765)
                     /locus_tag="ACN3HL_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005283.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDSESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(66981..68372)
                     /locus_tag="ACN3HL_000374"
     CDS             complement(66981..68372)
                     /locus_tag="ACN3HL_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HHC8005284.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(68357..68968)
                     /locus_tag="ACN3HL_000375"
     CDS             complement(68357..68968)
                     /locus_tag="ACN3HL_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HHC8005285.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(68972..69169)
                     /locus_tag="ACN3HL_000376"
     CDS             complement(68972..69169)
                     /locus_tag="ACN3HL_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005286.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     KMKNEIESDFKCCSLEKNVRG"
     gene            complement(69183..71876)
                     /locus_tag="ACN3HL_000377"
     CDS             complement(69183..71876)
                     /locus_tag="ACN3HL_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HHC8005287.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAK
                     NSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQG
                     TKTIDVRENLQSSSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDV
                     RENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIID
                     SEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDSLLKK"
     gene            complement(71863..72081)
                     /locus_tag="ACN3HL_000378"
     CDS             complement(71863..72081)
                     /locus_tag="ACN3HL_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005288.1"
                     /translation="MIENRLIDQVWCLDQNTDNLELIETICFNTIVLDLRSENDNCVT
                     HIIIDRKTAQKLSESLRKWAEGGNNENS"
     gene            complement(72157..73170)
                     /locus_tag="ACN3HL_000379"
     CDS             complement(72157..73170)
                     /locus_tag="ACN3HL_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HHC8005289.1"
                     /translation="MEEIDKLIAQYAYSKDDVYAEKYLKYPIFLDKHKKYKKMKQSTK
                     KVYMYLKKQNEYSLENSKVDSKGRIFLIFAIEKIAEKSCLTKKTVISALRELEEYKLI
                     TIKKNGFNKKTGKNNPNFYYLLKPEFSEGDFYKKKCIEENLHLPTNQHYSPSEKNTPS
                     DKSTFDGDKSFPLPGEKFLQELNHSSKDFKDFKESQNADFIDSLSVENKKLDEILIES
                     LIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIKSAEKEQKIQLKIIYEI
                     CNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGI
                     DKQ"
     gene            complement(73374..73655)
                     /locus_tag="ACN3HL_000380"
     CDS             complement(73374..73655)
                     /locus_tag="ACN3HL_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005290.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(73706..73912)
                     /locus_tag="ACN3HL_000381"
     CDS             complement(73706..73912)
                     /locus_tag="ACN3HL_000381"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005291.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            74076..74807
                     /locus_tag="ACN3HL_000382"
     CDS             74076..74807
                     /locus_tag="ACN3HL_000382"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005292.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            74861..76006
                     /locus_tag="ACN3HL_000383"
     CDS             74861..76006
                     /locus_tag="ACN3HL_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005293.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(76091..76396)
                     /locus_tag="ACN3HL_000384"
     CDS             complement(76091..76396)
                     /locus_tag="ACN3HL_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HHC8005294.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(76421..76852)
                     /gene="ruvX"
                     /locus_tag="ACN3HL_000385"
     CDS             complement(76421..76852)
                     /gene="ruvX"
                     /locus_tag="ACN3HL_000385"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HHC8005295.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(76849..77115)
                     /locus_tag="ACN3HL_000386"
     CDS             complement(76849..77115)
                     /locus_tag="ACN3HL_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HHC8005296.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(77370..78095)
                     /locus_tag="ACN3HL_000387"
     CDS             complement(77370..78095)
                     /locus_tag="ACN3HL_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HHC8005297.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(78456..78526)
                     /locus_tag="ACN3HL_000388"
     tRNA            complement(78456..78526)
                     /locus_tag="ACN3HL_000388"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78492..78494),aa:Gly,seq:ccc)
     gene            78643..79395
                     /locus_tag="ACN3HL_000389"
     CDS             78643..79395
                     /locus_tag="ACN3HL_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHC8005298.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            79411..79890
                     /locus_tag="ACN3HL_000390"
     CDS             79411..79890
                     /locus_tag="ACN3HL_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HHC8005299.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(80141..81721)
                     /locus_tag="ACN3HL_000391"
     CDS             complement(80141..81721)
                     /locus_tag="ACN3HL_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HHC8005300.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(81714..82457)
                     /locus_tag="ACN3HL_000392"
     CDS             complement(81714..82457)
                     /locus_tag="ACN3HL_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005301.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(82633..83408)
                     /locus_tag="ACN3HL_000393"
                     /pseudo
     CDS             complement(82633..83408)
                     /locus_tag="ACN3HL_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
     gene            complement(83656..84492)
                     /locus_tag="ACN3HL_000394"
     CDS             complement(83656..84492)
                     /locus_tag="ACN3HL_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HHC8005302.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(84503..85432)
                     /locus_tag="ACN3HL_000395"
     CDS             complement(84503..85432)
                     /locus_tag="ACN3HL_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HHC8005303.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            85624..85977
                     /locus_tag="ACN3HL_000396"
     CDS             85624..85977
                     /locus_tag="ACN3HL_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HHC8005304.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(86051..86707)
                     /locus_tag="ACN3HL_000397"
     CDS             complement(86051..86707)
                     /locus_tag="ACN3HL_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HHC8005305.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            86933..88867
                     /locus_tag="ACN3HL_000398"
     CDS             86933..88867
                     /locus_tag="ACN3HL_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHC8005306.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(88953..90176)
                     /locus_tag="ACN3HL_000399"
     CDS             complement(88953..90176)
                     /locus_tag="ACN3HL_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HHC8005307.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(90170..92041)
                     /locus_tag="ACN3HL_000400"
     CDS             complement(90170..92041)
                     /locus_tag="ACN3HL_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HHC8005308.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(92062..93180)
                     /locus_tag="ACN3HL_000401"
     CDS             complement(92062..93180)
                     /locus_tag="ACN3HL_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HHC8005309.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(93263..94096)
                     /locus_tag="ACN3HL_000402"
     CDS             complement(93263..94096)
                     /locus_tag="ACN3HL_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005310.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(94089..95006)
                     /locus_tag="ACN3HL_000403"
     CDS             complement(94089..95006)
                     /locus_tag="ACN3HL_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005311.1"
                     /translation="MIQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(95029..95208)
                     /locus_tag="ACN3HL_000404"
     CDS             complement(95029..95208)
                     /locus_tag="ACN3HL_000404"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005312.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            complement(95233..96357)
                     /locus_tag="ACN3HL_000405"
     CDS             complement(95233..96357)
                     /locus_tag="ACN3HL_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHC8005313.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            96540..97448
                     /locus_tag="ACN3HL_000406"
     CDS             96540..97448
                     /locus_tag="ACN3HL_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005314.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            97589..99202
                     /locus_tag="ACN3HL_000407"
     CDS             97589..99202
                     /locus_tag="ACN3HL_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8005315.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        29637 a        20222 c        16269 g        33627 t
ORIGIN      
        1 tatgtactgt aataaataaa aaaactgaga gaaagctgat ctactcgctt tctttcagtt
       61 tttatttttt tcgatccatc tctcgactgc ccatcggtgg ctaccacgtt tcaatttcac
      121 aagcgcttct tgagggctca cccaccaaat tttattggtc ttttcagttg gttctcctat
      181 acgcttccaa gaatcagcaa caaagaaata tcctggatta taataataag ttgcacgata
      241 attcgagtaa aaatactcat cagcttctcc cagataagaa gaaatttctg ccacaattcc
      301 catttcttct atcagctcac ggacaatcgc ttcttctttc gtctcttctc cttcaatttc
      361 cccgccagga agaaaaaaag caccatttgg agcctcgatt actgcaatct gctgatctct
      421 ttctatgaca atatatgctg cataacgggt ttgataatca gcaaattgct ttttttcacc
      481 aaaaattggt ttatccatga atagtttcca ccttaacagt tttattttct atccatttta
      541 catgagaaat ttctcatgaa caagcacaaa tcaactattt ccttacttct ttttgttatg
      601 attgagtaaa aggaaaagga gagatgaatc tatgaaaatg gctcacacat gtgttcgagt
      661 gaaagatctt gaagcatcaa tcgaatttta tcaaaaggca tttggttttg aagaaagccg
      721 ccgccgtgat tttccagaaa acaaatttac acttgtttat ttgacacttc ctggggatga
      781 ctatgaatta gagttgactt acaactatga tcatggtgcg tatgatctag gagacggcta
      841 tggtcatatc gctatagcag ctgatgatct agaaaaatta cacgagcaac ataaagctgc
      901 cggtcttgag attactgact taaaaggatt acctggcact gcgccttctt actactttgt
      961 cattgaccct gatggttata aaatcgaagt catccgagga tagttagtat ggggcatttt
     1021 actcttgatt gaataaaaaa caaacaccaa taattaaaat gagacgcaaa cttttcatta
     1081 aattgaaaaa gtttgcgtct ttttttaaca accattgtag ctataaggtt gccactctcc
     1141 accaatttat ttttaattca tttgaaagaa atcaaataaa cgaggtacct ttagaaaaca
     1201 aaactgcttt tcctcctatt atcacacgat cttcttttaa ttcacattct agatccccgc
     1261 cccttgatga catttgataa gctgacaatt ttgttttatt cattctttct gcccaataag
     1321 gaataagatt agaatgtgct gatccacata ctggatcttc attgattgtt aattttggaa
     1381 agaaggttct agaaacaaag tctttttgca cactttctgc tgtcacgatg actcctattc
     1441 ctaattcaaa atttttgata gctgtaaaat ctggctgcaa tttagccacc gttttttcat
     1501 cttctaatac gaaaaataaa tcacgtgcta agtaggcttc tttaatctta gccccaatcg
     1561 cttcttcata ttcagacaat atcggcactt ttttcggcat aatactagga aaatccatgt
     1621 aataataatc tttaattctt gtcacaaata gattaccgct ttgagtagaa aatttaatcg
     1681 tttcatcagg tattttgtaa tagttaaata aaacaaatgc tgttgctaat gtcgcgtgac
     1741 cacaaagatc gatttctcga tctggcgtaa accatctaag ctcaaattct tggtttttct
     1801 tcactgtaaa tgctgtttca gataaattgt tttcaatggc aattttttgc atcgtacctt
     1861 ctggcagcca ttcttctagc acataaaccg ctgctggatt tcctttgaac acctcatctg
     1921 caaatgcatc aactacgtaa taatctaagt tcattttaaa gcccctttct ctaatttgtt
     1981 ataaatatat tctgcacaac aaagatcttc aatagctaga ccaactgcgt cgaaaatcgt
     2041 cggcctcgat tctcctttat aaaatgtttt tttctcagaa actaattcgc ctaatgtacc
     2101 aacaatacaa gattcctcta aatctccttc tgccatggct ataagcaggt ccccgctttc
     2161 tgttaaggca gctgagtaat catctacata gatttgagaa gtttccatca acgatgtact
     2221 tatctctctt gtatcaggag taaatgtgcc cacagcattg atatgtgcgt cttcccttac
     2281 ccactctttt tgaagaaatg cctctttact agaggtcaac gtacaaatga tttccgctgg
     2341 acgtactgca tcttctactg atattgcatt tataaacgtt attttaggat actgtttttt
     2401 agctttagcg ataaaagtat ttcgtctttc ttctaaaata tcgtaaacaa acactgtagt
     2461 gatgggacga atggtagaaa tcgcagtcaa atgcgacaat gcttgttgac cagctccaat
     2521 taaagcaagt gtttctgcat gcggatttgc taagtaatct gttgccagcg cagatacagc
     2581 agctgttcga atccaggtga ctgcatttgc gtttatcaat gctttgggta gtccgttttg
     2641 agcatcaaac aagaaaatct ctcctaaatg agaaggtaaa tgatactgat gattatccgg
     2701 aaaagcggta atgacttttg tgccaaaata tctgttctcc cccaaataag caggcatcat
     2761 cgcaaacata tttttgcctt ttccgtcagg taaaatttcc accaatcgag gattttggct
     2821 gattttacca ctttcataat caaaaaaaca ttttttcatt acttgaatcg cttcttcaaa
     2881 actaaaagaa gctactactt cctcaaaatt aataattttc atagacaatt ccctcctcac
     2941 aaaagattaa cttctaaaat caatacaatc aatggtaaaa ttgtatggta tacaatttta
     3001 aggagtggag aaaatgccta ttaattctta tgacaattac ccgttaactt ggcgaccaga
     3061 caaacaaaaa ttgaagcgtc cttattatcg atcgttgatt caacaattag aacaagatat
     3121 tttaaagaat aaattacaga aaaacactca gttaccctcc caaagagagc tagctgatta
     3181 tttagattta aattttacta ccgttggcaa ggcttataaa tatggaattg agaaaggttt
     3241 gctgtatacg aatattggaa gtggcacatt tatttctccc aatgtctttg agtccatcac
     3301 catctctacc aatgaagtaa ccgaacatat cattgatttt ggtctggtta gttcttttga
     3361 agaatgtaat aaattcgttg tcccgtttat tcaatcaact agtaataacc caaatcttgt
     3421 tggtttgctt aattaccaag atcccaaagg cacaaatttt caattgacta ctgcagcaaa
     3481 ttggttaaaa actcaaggag tcattccgtc cttagaatct ctatctattg tttccggtgt
     3541 tcaaaatgga ttggctatca cactttctgc acttttctct ccaggtgata gaatagcaac
     3601 agaccgatat acatacgcta atttcattga attggctcag ttatatcatt tagagatcgt
     3661 tccaattgat tttgacgagc aaggaatgcg acctgatata ttgattcagg aatgtagaaa
     3721 aaagaagatt catggtgtct ttcttatgcc ttcttgtaat aatcctatag ggtttcaaat
     3781 ctctcacaaa agacgagagc aattagccga agtgattgaa aaagaaggtc tatgggttat
     3841 tgaagatgat atccattcat ttttaacaac ttactatcaa catacgatca ttcctccttt
     3901 ccaaaattta ttacctaacc aaacaatcta cttagctgga atgacaaaat ttatttgttc
     3961 tggattgcga gttgcttatc ttgtagttcc agtacatgtc caaagcaaga tagaacaagc
     4021 aatttttaat ataaatgtga aaacttctgg attagatgtg gaagtcatca ctcaaatcct
     4081 ccattcaaat gaagcaaata ggatcttaga aactaaatta agtcttacaa aaagagccaa
     4141 tcagcttttt gattctcttt tcaaagtaga aaaaccaacg aatcgtgtcc cttactatcg
     4201 aattcttcca gttgatcctg agattgaccc taagataatt gagaatgact ttcttgctaa
     4261 cggtatccga ctttatcatt ccagacgctt tactacacgt gcgcaaccag atgcattcgt
     4321 tcgaatttcc ctatcctcta ataaccttga aattttagct tctggactaa gtatcgtaaa
     4381 agaaaaaata aaaaaatatg aattataacc tattgataaa taaaggaatc aaatcttatt
     4441 gattcctttc aataaaaaag aggcactacc cgaggttcaa caacgggtag tgcctcaaaa
     4501 aataaacgaa cattttgcac ttaaagtatc caagaagcaa gaaaaattat tttattttct
     4561 tattttacta aatcactagg tttctgtcag aagatgaaat tatccaatca tgacactttc
     4621 ttctggatat ttgtattttg attgtgttct ttgtgctttt gtcatcagag agaagaccac
     4681 agtcaataca ccaactcgtc caatgtacat aagcgctata atgatcaatt tccctattgc
     4741 agtcaagtct ggcgtcaatc ccatcgtaag acctactgta ccaaacgcag agaagacctc
     4801 aaaagcaata tattcgatgc cagaagtttt aggtatcgtt tcagtcaccg ataaaatcat
     4861 gatggcgact acacacaacg tcaacgtaac aaaaaataaa gtaagtgccc gcaacactgc
     4921 gccttgtcgg atggtacggc caaatgcttc cgctctcgta cgtcctttca acatcgaacg
     4981 catctggatc agcaacacac ctaacgtagt tgttttcaat ccgccggccg tcgacccaga
     5041 tgttccgccg atgtacatca aaaacatcgt taaaatcaga cctgcatggc tcatatggag
     5101 gtaatcaact gaataatatc cagccgttct aggtgtcaca ctcataaaaa aggtgtttgc
     5161 caatcgttga aacatattcc cttccactag cgttgcccca ttgcgctctg tgaaaaagaa
     5221 cacaacgaat ccgcctaata aaagggtacc tgtaacggtt aatgcgattt ttgaatgaat
     5281 cgtcatcttc tttttctgat gatattccag taaatcacgc catacgatga agcctaaccc
     5341 accagaaatg atcaaagcag ataccaccat gatcaaataa acattttgct ggtgattggc
     5401 taaactgtct cctaacaaat caaaccctgc attacaaaaa ctagagattg catggaacaa
     5461 actgtaccag atacctttca accagccaaa ttcaggcaca aatacaaaag ataaagcaac
     5521 cgtaccaatc aattggataa caaaggccaa ttttaggatg taaagcatga gcttcatcac
     5581 acctgatact tcttctagat tcagcgcttc ttttaatata atacgtgtgc tgagactgac
     5641 tttcttcttt atcaatgcaa agcatagaat cggaaccatc ataaaaccaa gaccgccgat
     5701 ctcaatcaaa agcatgatca aaaattgacc agcactgttc caatgctctg ctgtattcaa
     5761 tgttgtcaat cccgttacac agacagcaga agttgcagtg aaaagcgcat cgataaaatt
     5821 tgtcccatgc ccactattac taaaaaatgg tagggtaagt aggccgccgc caactaaaat
     5881 caggagaaaa aatcctaatg cgagaagctg aacagccggc aaacgtttct ttatttgttt
     5941 gctttgttta atcatcgttt tcctctttta aaaaaagata ccacttagtc agtggtaccc
     6001 atatttttta ctttgatcaa ccttgttact tctgcgcgct cgttttcttc cagcttcata
     6061 cgaatataat agatcgtttc ttctaattga gggatcgtca tatattctaa tgcattgact
     6121 cgccgacgtg tcttttcgat ttcactcgcc atcagttgac aagttttttc gatttctgtc
     6181 agttccaaaa gttttggaag cagggtagta aaccgatcga ttgaccgatc cagttcggca
     6241 ctggaattca aatacccgta ttccaaaggt gtgtctgtca gctgttcatc atattcaaaa
     6301 ttcatcacag gtacttttac actcatgata tttttgtcta cgatagacaa atcaacgttt
     6361 tccgccggca aaacaaataa ttcttcgatg aaaggttccg tgatcgaagc atttgccaat
     6421 acaaaatcag acattgcttc tgtcatagac tcttccattt cttgacgcag ctggttgttc
     6481 tttcgaatca acaggatgaa ttgacgcatc agttcatctt gcttatcttt taataattta
     6541 tgccctcttg tggcagttgt caactgtttt ttcaatcgag tcaattccat gcgggtcgga
     6601 ttcacattca atcgtgccat cagaactcac ttcccttctg gcagatattt gtccagcatg
     6661 tcgtctttga ttcgttttaa ttcggttctt ggcaacatcg atagcagttc ccaccctaga
     6721 tcaagtgttt cagtaatcga acggttcgtg tagaatcctt gattgacata ttctttttca
     6781 aaccgctcag caaacttcgc atagatcttg tctacatcag ataaagcaga ttcacctaaa
     6841 actacggcta attcttttgc ctgttttcct tgtgcatagg ctgcaaaaag ctgattcatc
     6901 gtagctgcat ggtcttctct tgtctttccg ggtccagttc ccttatcttt taaccgcgaa
     6961 agagacggga gtacatcaat tggtggctga atcccactct tgtaaagctc tctagtcaag
     7021 atgatctgtc cttctgtaat ataaccagtc aagtcaggga ttggatgagt tttatcgtct
     7081 tctggcattg ttagaatcgg aatttgagta accgatcctt ttagtccgcg gattcttcct
     7141 gctcgttcga ataaagtagc taagttcgtg taaagatacc caggatatcc tcttcttcct
     7201 ggaacttctc gccgtgctgc agaaatctct cgcaatgcct ctgcatagtt ggtcatgtct
     7261 gtcatgataa ccaaaacatg cattcccttt tcataagcaa gatattctgc agcagtcaaa
     7321 gccatacgag gagtagcgat acgttcgatt gcagggtcgt ttgctaaatt cataaacatg
     7381 acagaacggt cgattgcgcc cgtttgacga aaatcttcca tgaaaaattc agcttcttca
     7441 aaagtgattc caatagcagc aaagactacg gcgaaatcat ctgatgaatc gagtaccgtt
     7501 gcttgtcgcg cgatctgagc agctaattct ttatgaggaa gaccagagcc agaaaatact
     7561 ggtaattttt gcccacgaac taatgtattc aaatgatcga ttgcagagat acctgtttgg
     7621 ataaactcat ctggataatc ccgagctact ggattgatta cttctccgtt aatatccaaa
     7681 tgcttttcag gcaggatctc tggtccgtta tctttcggtc gtcccaaacc atcgaatact
     7741 cgaccgatca tgtcttccga tacacctagt tctaaaggat ggcctaaaaa tcgtacagaa
     7801 gagtcacgta aattgatacc acttgttcct tcgaatattt ggaccattgc tttatcttct
     7861 tggacttcca atacttgtcc acgacgaatc tcgccatttt gcatacggac ttcgattaat
     7921 tcttcatatt tgacaccagc aactttttca accgccatca atggaccgac gacttcaccg
     7981 atcgtacgat attctttaat cattgctcat gcctccttct gaaacgatcg tttgcatcgt
     8041 ttgcttgatt tcaccaataa tttgatctag tttttctaat tctgtttccg ggatatattt
     8101 gcttcgtccg atcctttcac gaatcgatac ggtaccgtcc atgatctcac ttaaataagc
     8161 acctaacgac aacgcacggc gtccttcttc accaaaggtc aagatcatct tcaacatttt
     8221 gaattgtttc tctcttgaag tgaatgtatc gacatcatca aaagcatttt gctgcaaata
     8281 atcttcacga atggattttg ccacttctaa tgtcagacgg tcattatctg aaagggaatc
     8341 aatccctacc aaacgcacga tttcattcag ctgctgttct tcctgcaaaa tacgcatgcc
     8401 ctcggtgacc atggatgccc agtcagcttg aaggatatga tccatatact tccctacttc
     8461 tgttgaataa agagaatagc tttgtatcca atcgatcgaa ggaaaatgtc ttttttgggc
     8521 taaactggaa tcaagacccc agaatacttt tacgacccgc aatgtatttt gtgtgactgg
     8581 ttccgaaata tcccctccag acggggatac agcactgatt gcggttatac ttccttcgcg
     8641 accttctgat cctaatgcaa tgactcttcc agatcgttca tagtattccg caagccgtga
     8701 accaagataa gctggataac cttcatcacc aggcatttct tccaaacgtc cgctcatctc
     8761 acgaagtgct tctgcccatc gtgaagtgga gtctgccatg atagcaacgt cataacccat
     8821 gtcacggaaa tattccgcaa ttgtgattcc cgtatagata gaagcttctc gagctgctac
     8881 tggcatgttt gatgtattag caatcaatac cgtacgttcc atcaacgatt ctcctgtatt
     8941 agggtcaatc aattcaggga attcatttaa aacatccgtc atctcatttc cacgctcgcc
     9001 acatcccaca tagacaacca tgtccacatc ggcccatttt gcaatttgat gctgaacgac
     9061 tgttttccct gcaccaaaag gaccaggtac agctgctgct cctccttttg tcactgggaa
     9121 gaatgtatca atcactcgct gtccagtgat catgggtgca tccgggttta atttttcttt
     9181 gattggccga ctacgtctta ctggccattt ttgaagcatc gtcaaatttt tgtcaccatt
     9241 ttcggtttca atgacacata ctgtttcatc aatagtgaat gaaccttttt cgattgtttt
     9301 gatcgttcct tttatcccat ttggcaccat gattttatgt tttataactt ttgtttcttc
     9361 tacgatcccg ataacatctc cagcactcac cgtttctccg gcttctactg ttggttcgaa
     9421 ccaccatttt ttctcatggt ccaatgcggg caattgaact ccgcgcccta agaaattact
     9481 ttgtgtgatt tccataaagg tatctaatgg ccgttggatt ccgtcaaaca tttgtgaaat
     9541 gatccctggt cctaattcaa cagataaagc ttcaccagta gagcgaaccg gttcgcctgg
     9601 accaattcca gaagtctctt catatacttg aatagacgcc acatcgccac gcatctcgat
     9661 aatttctccg ataactccta gatctcccac tagacacatg tcttggatac tggcatcaga
     9721 catgttctca gccattacaa gaggtccgga gacttttatg atttttccaa tttgcaaaat
     9781 ttctatctcc ttttcatact ataagatatt ttgacctact gctttttcta cgtttttttg
     9841 aatttcttcc agccctatcc ctaatgatcc ttgatgattg ggaatcaata cgatagcagg
     9901 tatcatttgt tccttgtaac gttcgatcgt ttctgggctc aatgctgcac attgctctgt
     9961 gacataaatc acgccatact cattctttgc catttcttca attgcctgac gaacggtttg
    10021 cttggttgta ccataacgaa catcaaagcc aaacaatttg aatggcaaaa cagaatcttt
    10081 gtcgccaact acaccgatct tatgcgtcat agacttgtct cacccgcttt ctgattgttt
    10141 ctggttcgaa atggcttctt ttgccgataa ccagtaaacg aaggtttttg ctttctacct
    10201 cttttgcgtt caaaaaggct agtagtggca gtggtccgaa agcctgggtt tgtgcttctt
    10261 gatacaatga acttagataa tcatctttca actgttcaag ctttacgaga tcaagatttc
    10321 cctcacggat gacagggcgc agaaaatcag cataatctgt ctctaataga aaattcgtgt
    10381 aatcttccat atctttatct acaaagttca aaaatacttc tttttcgata cttcccgagc
    10441 tggaaagtac cgtcgtcatg aacccatatg ttcttttctg caatattcct cgagccatcg
    10501 ttgtgatatt ggtcaagtca ataaaagcaa tgacttctgt cagcaattct tgatatccta
    10561 gcttatcggc aagccgtcgc tgctctgtca aaaactgtcg atcataaatc acgtcaattc
    10621 cctgaagaat ggtagactct tcaaaataat cacgtacttc tcgtatactg tccataatgc
    10681 tttcagggag ttcatttgaa acttgcgtat gaatggcatc cttcaaggtt tctaatgaat
    10741 aaaatccatc gtcgatatac aaatggtcca gattttgatt tgtcatctcg gcttttgtca
    10801 aaaccttcag attatggaaa gtatagcgca tcgtatagat ccaaacgatt tcaggctccg
    10861 gtgctgattc ctttaaccag cgaaatagac ggctctgctc ctttaaaaga ttctgttcga
    10921 agtcatattc atatccgtca taaatatatg gactgtaaat cgtggatttc aatatttcac
    10981 caagtgcttc gacagaattt gtttgaatca tccgttcaaa tgtctcattg gacaaaagtt
    11041 caagctctct tccgcgaatc aagggattta gttcgtggta ttccatacac tgatccctcc
    11101 ttattcgaat aattgattgg caatctcaaa actcatcgtt ccttggatat cttgtacaag
    11161 gctgctgaaa agaaaattat actgaactcc ttgatcgttt atcagaaaac ccgcttgatc
    11221 agcaacagtt tcatcactta aaaccatcat aaagggaagt tcattgttcc attcatccag
    11281 caatgtctga gaaagataag ctgctgattt ttctccagca atgaatgtta ctttgcctgt
    11341 caaaggtaat gaatacaatg aatttttgat aaactggatt tgttcagatt catcccaatt
    11401 ctccatttca gctattgcat ctgcaaacaa tcgtcgtaaa aattcctgct tcgcattcaa
    11461 attttcttgt cgtacttcta cttgttggcg attcctaagc tgacggtatt ttttttcaag
    11521 taattcgatt tgtttttctt tttgtttttg atgttctgtt tcgatttgcg tacgtttttg
    11581 ttcaaagttt tgatcgatct tcattcgctc ttcttgctct aacgccgctc tttcttgctc
    11641 tgctgcttca ttcatctgag agatgatttt ttcaatggcg ttcatctgct tttcctcctt
    11701 tatgcttagg cattcaatac taataggaag gaaataacga aacctaaaat cgcatatgtt
    11761 tcaaccatcg cagcaaaaat gattcctttt gtagcatgtt caggtttttt cgctaaaatt
    11821 tggatacctg ctgctgcaac tttcccttgg gcgatacctg aaaacaaacc tgtaaaagca
    11881 atcggcagag aagcgcctag aaagttcaat ccttgtacaa ctgacatatc atttcctaag
    11941 ttgataaaaa tcaaaaaggc gataacgaat ccatacaacc cttgcgtacc tggaagcaat
    12001 tgcagaatca aagcctgtcc gaatttttcg ggttgacttg ttgttaacgc tgctgctgcc
    12061 tcacctgtca ttccaacacc tttagctgaa ccaatccctg aaaaaatcgt cgctgttgcc
    12121 atcgctaata ctgcaaatac cattccacca ttttgactaa ttaagtaatc catcattgta
    12181 taaaaatcct ccaattattt attgtttttt ttcttatgat tgatgttgac gtatttttcc
    12241 gccgttttca gcgggtcaaa ggcacgtccg cctcctgtat aaaattttcc aaaaaattcg
    12301 acatactgca atcgtgcacc atggacatag gcacttaaca gtgtcaaaaa catattcagt
    12361 gcgtgtaaag cgatgatcaa aaggatccct acactgaatc gagcggctgg cggcatgaaa
    12421 gcaactagca tattgaatgc cgcgccaata cttccgcctg aaatacctag tgccatcaaa
    12481 cgtgtataac tgactaaatc accgatataa ccagtcaatc cgtaaagatt atacgctcct
    12541 ttggcagcac ccttgacttt agacggcgat tggataatcg gcacgattaa gatacataaa
    12601 gcagcaatga tcgatagccc cgcgccaaga taaacaaatg ctgtattttt tatcaacatg
    12661 acaccaatca atgcaataac gatcccaatc aggatccctt gccaggcaaa accatcactg
    12721 acagcactca agtaatcttt cctcctgata ttttcctttg ctgccacgaa taatccaacc
    12781 aagatctgta tcagaccgaa aatcacggat aaaatcaaaa tcgtattgac gtcatccgtc
    12841 gtagatagga ttgggaaagg caagcggata ccaaatagtt cttttggtaa tgcctgtccg
    12901 aaaaatgaac tgtagatcaa tccccagatg atcgatggta ccgagagaat ctcaaagaat
    12961 tttacgaaac gtttcatccc gcggggtaaa acaaatagtt tttgagctag tattgtccca
    13021 atgagcatca gcaatccgta accaacatct gcgaccatca tcccgaagaa gacaagataa
    13081 aatggtgtca tccaaggcgt tggatctact tcttcatatt ttggcagact gtacatttca
    13141 gtcagcaatt caaaaggttc gataagcgga tggtttttca atttagtagg gacttcctgc
    13201 tgaatctctt ctgagtttgg tgtttcgaaa ctaacgtata tatcttcttc tgatacagtt
    13261 tcgtttaaca catgcatcaa attctgtttt tcttctgcat ctacccaacc ttgcaaaacg
    13321 atcagataag tggcatggat aaaccgttct tttacttttt cccgttctgc aacggcaagt
    13381 gtgacttctt ctacccattc aaattcttgg atatagccgc tgcactgacc taacgctgtc
    13441 gttatctttt tttgctgctc gtgaacaatg gataattgct gtttggtttc ttgcaatttt
    13501 tctttaggat tttgttcata aggatacgtt tctttattga acccgtattt cccagcaatt
    13561 tcttctatag cagcaactga tttttttaaa gcaacatacg aaagataaac ttgttttggc
    13621 gtataatcta tttcttccat ataaacgtca tcaagcttac ttagttcttc cttgaaactt
    13681 tcaaaatttg ctgcactcac agtccccatc tcaaaaatgg tcgtcttact tgcatacata
    13741 cttggagcaa tatccagctg ttgccaatga agaagccatt cttcctcttc ttctaaacga
    13801 tcacgttttt cagttagctg ttcccacttt tcttttaaat caaggacttc ttctaattta
    13861 ttcatgaaat tttcttcgga ataatttgct tccaagtctt gtaaggaaag ttcttgacgt
    13921 ttcaaatgga gtttcttttg acggctatcg ccgtggtgtt gtatgaattg gatagcttct
    13981 tggatgtctt tcagccgatt gcctaaagcg cttaattttg cttctttatc aataatcgtg
    14041 gtatctggaa aatatttttc tacccactgg ttgtttgttc tattttgata cagatcccgg
    14101 atttcaacat tttggattcc ttgtactgct tgtaaaatcc tctcctgatt tcttttatct
    14161 gaaatgaggg tcactttttc catcttagtg acggccataa gtttctttca ccctttcaat
    14221 gattgcaccg attgcttgac tctgatgctt ttgatattgg tctttcaaag ttgcttgcac
    14281 cttgtctgct tctgctttca atttcatttt ttctttttct aattcttgct tttcgaattg
    14341 ttctttttct tctaccaact gtttcagctg ttgccgactg ttcgtttgga ttatctccaa
    14401 ttcttgctct ttttcttctg cataggtctt caactgctgc cgtagggttc gagcacgctt
    14461 ctcattttct tcttctgctt ttcggatttg ttccaaagct tctaacactt gcttcacttc
    14521 ctttcgattt aaaaaagagg tacatgcttt cttttttcat tgaaagtatg tacctctaaa
    14581 gataacttag tataggcagg ccccttcaat aaaatgtcct tctcacccct tgaagaacta
    14641 gatccttgaa gcttacgccc aaccttttta tttctgctta ctttttatta taacaaatta
    14701 agcaatattt tcaactatcg tcatgaattt cacacgaaaa ttctctttac agatagtaac
    14761 acagcaagaa cagataagta taggggcaag tcttacatag tttaaatttt tttaaatcct
    14821 tgttacaatt agtctacttt agggggaata aaaatgaaac caatcatcgg cattgccggg
    14881 aatcaactga ttcgagcgac agatactttc caaggaaatc aagtaagcta tacaccgcag
    14941 ggatttgtgg atgcagtttt agatgctcaa ggattacctc ttattctgcc agtcatgtct
    15001 ccagattcag cgcctcaact aattgagaaa atcgacaaac tcattcttgc aggcggtcag
    15061 gatgttagtc cgcaacttta catggaagac cctcatccaa aactgacgga aacaaatatt
    15121 caacgagacc aattcgaaca ggcattgatc ttggaagcat tgaaacaaag aaaaccgatt
    15181 tttgcagtct gccgaggact tcaactattg aatgtcgtgt tggagggaac actttatcaa
    15241 gatctttcat tatatccaaa atggtccgta aaacacgaac aacagcccac tgccccgcag
    15301 tttgcaactc acgaagtcaa aatcgtttcg gacagtttat taagtgacct tctccctgat
    15361 tcatactttg tgaattccta tcatcatcag gcagtcaaag atctttctcc tttgttaaaa
    15421 gccatcgcct tttccaacga tggactcatt gaagcagtcc aaagtaaaga taatatgcac
    15481 aaaatccttg gtgtccaatg gcatccggaa ctttctcatc gtgtagattc atctgaacag
    15541 cgtttattcg atttctttgt gaatgaattt taatcgtttt tctgattagg tcgtgagcct
    15601 gccgttcaac tctgagtcac aaggagcaat ttcaaaaaac agcttctcat gtttgttgga
    15661 tattgtgact tgtgaccgag gagttggcag gagaacaccg tttaaggaag aggtcgtgaa
    15721 atcagcgccc tgacctgagt attagagaaa taaacagaaa aatagcttct aatattttac
    15781 cgttttttga gctaattccg aaggagactg cgacacgcct tttgttgcag tcgcttttta
    15841 gtctattgag caatgttggc tagcattttt ctcaatcgtc ctttcgataa tccaacagcc
    15901 tttggagttg agtaatctgt tgctgtaatt ccattccttt tgtcgtattc cgattaagtt
    15961 tgcgtgggag ctgctgctcg atcacttttt ttacattcgt ttgatcagat ttttttgcaa
    16021 attgttgttc aataggcaag aacggataat gtgtcacgat ttggaaaccg taagaattgc
    16081 atagtaatga gtagccagca atcccggttg ttttttgata agctttggat agacctccgt
    16141 caataacaaa tgcttttccg tttgctttga tcggtgactc tccttttttt acttttactg
    16201 gcgtgtgtcc attgatgatt gctgaacctt cttcttttgc atcgaattct gccaaaattt
    16261 tttcactgaa ccactcttca tctcgcaagt gataataggg attgcttttt tcgacgtgcg
    16321 tatgaggctc tgtgagaaaa tagcgctcaa aagttgccat tttactcttg ccgaataaag
    16381 gcgaaaatgg cccgctccac gcataccaaa tcaaatcggt cgccaaatct tcatttgcag
    16441 tcaaatcttt tgcgctttca gttatctgtt tttcaaaaaa tcccagcagt tcttttccgc
    16501 gataagattg gtctaattca aatgctaaga gctgcccctt ttcatctaca ggtatacagc
    16561 catggaacag tacatgctga ttgttcgtga gatacattcc ccctttttcg atcaaaaacg
    16621 tcatgtgttt ttgcattctt aacgagtgct ggaatgaata catcaaacta tcgatcactt
    16681 tttgttcctc ttccaagaat tttttaggat catctggctg gatcgtttga aaacaagtcc
    16741 ctttcaactc atagagctga ccttctaaaa cgatcgttga ttcctcatag ttgatttttt
    16801 ccaacaattt acgatcgtcc attttaaatt caggtcgtcg attcaacaac tgatgttctg
    16861 atttgaattg gaggatagaa agtgcttgat ggatcttttc taattcttct tgctctcttt
    16921 cagatagatc tttcctgttt ttaggggtaa atactggatt cttctgatag gtttgatggg
    16981 caaaagaaaa taatggacgt aaatttaatc catattcttt ctctaattca aataaatagt
    17041 tgtagcgtgc ggcaatccgt aaaagcgtca ataaacatgc ctcagagccg caatacgcac
    17101 caatccacaa aatatcatga ttcccccact ggatatctac agaggaaaaa tccatgattc
    17161 gatccattac tttggctgct tgagttcctc gatcaaaaat atcacccacg atatgcaaat
    17221 gatcgatgac agatttttgg atcgtctgcg caagttttgt taaaaatttt tcttcttcct
    17281 tcatcaagac aagttgttca atgatttttt ttacatagtc ttttttcccg ttgatacgat
    17341 catcgatata caagagttcc tcaatgatat agctatattc tttcggcaat ccttttcgaa
    17401 cttttgatcg agtgtatttg actgtcgtaa accgtaaaag atcgatcaaa cgatggatca
    17461 gctgggattt atcttgtttt ttgtaccaat cagtcgtcaa cacatattct ggataagccg
    17521 taaaaatagt gaattggctg atctccgttt ccgtcatttg ttcagagaaa aggtctttga
    17581 tcttttcttt aagatttcct gaaccgatac gcagaatatg atcaaaagca ggaaattcgc
    17641 catgtatatc gctcaaaaat aactctgttc cttttggaag ctgcaaaatt gcttcgagat
    17701 tgatgatttc cgtgatgaca tcttccgttg tagggaactt ctctgaaagt aaatctaaat
    17761 agcggtccat taaaacgcct ccaaaaattg gtatactcaa cattataaag ttgttatgct
    17821 ctattttcaa tgaatatata tatccaatat aataaaaaaa tagaaatagg tctatacaaa
    17881 aaagaagctg ggaacaataa atgtccagct tccttctata tttttctata ttttatgctt
    17941 tttttcgttc atttctcata attgaaatcg attgtttcaa tgaactccat aatccgcctt
    18001 cgctatacac gagtacattc gatttgtaca tgtttgcaga caagatcatc aataagaatg
    18061 ttacggctac aagtaccaac aaggaaatca atgctccacc cataccgact gtctcatttg
    18121 ctaagcgaac cggcataata tatgaagata agaatggaat atacgaagtg atccgaataa
    18181 cgatattgtt tggatctgaa gctcctagta tcaatccaag catatatccg cctagagata
    18241 gataagtcac tggcaaaatt gcttttgctg tatcttctgc tttgttgacc aaagagccac
    18301 ataaagctgc taaaacagaa aaaatcaaaa tgccaaagat catgaataga agagaatacc
    18361 acaagaatgg tccaatcaag ttatccaatg agataccgtc taatatattt ttgaccattt
    18421 ccatatcttt gaattgactg tatcctatac caaaaataat accgtataat gccatttgcg
    18481 ttaatgcaac aagtaaaaca cctgttagtt ttccgtaaaa atgcttttgt gcagtcgtac
    18541 tggacaggat cacttccatg atccgcgtgc ctttttcaga agcgatctct tgtgcaatga
    18601 tctgcgcata cgtcaaaata ataatgaaca agacaatcgt tgctacataa cttacgacat
    18661 attggactgt cgagttatct tctccaactg tcatttttcc ttttgaatca aaattgactt
    18721 tttgtcgagt caaacttgct tgttggctca agctagctac ttcttctggt gaaatgccta
    18781 attgacttgc tcgaagcatc gattgcaagc cagtcagttg ttgttgtatc agtagttgtg
    18841 tactttgtcc taatgaattt tcgctataaa gcatcccatt tatcttatca ttctcagttg
    18901 agactactaa atacgcatcg attttttctt ccgaaagctc tttttgtgct ttttcttcag
    18961 aatcaactgc tttgaactca aaatcatctg ttttgacttg gctcatttgc tgactgattt
    19021 gctcattatc agccaatacg ccgattttat tgacatcact attttgttga gcaaagtttc
    19081 ctgctacata aatgataccc agcatgataa aagggactaa tatcatgatc aagaaagaaa
    19141 tcgacttaac attttttaaa tagacatctt tggtaataat ccaaaactta cgcatcgatt
    19201 tcacctgctt tcaatttgaa aatctcttcc aaagttggcg gttgctggtt aaacatagga
    19261 atgtagccga actgagtcgc acgagtaaag atttctttcc cagcttcagg atcttctaag
    19321 gtaatctcta acgtattgtc ttcatgaagg atcacttttt tcacgccttc gatttcttct
    19381 acttcctgtt ggcttaaacc agattccaag aataacttcg tacggccaaa tgattcacga
    19441 atctcatgta cttttccatt caaaaccatt tttccgtttc gcaacatgat caaatgatcg
    19501 cagatttttt ctacattatc catattgtgg ctagaaaaaa tgacacatga accatgtttt
    19561 ttcaattcca atattccatc ttttagcaat tcagcattta ccggatctaa cccgctgaat
    19621 ggctcatcca aaatgatcaa tttaggttca tggattaacg tggcgatcag ctggactttt
    19681 tgctgatttc ctttagacaa agattttact ttatccgtct ttttcccttt tacctgaaat
    19741 ttttccatcc aaaaatcgat ttttggttca atctcttttc ttgatttccc tctaagttct
    19801 gcaaaataaa gcagttggtc ttgaatcgtt actttcggat aaagtccccg ttcctccgga
    19861 agataaccga tgacatcata atctttctcc ccaagatgat ggccattcca taacacttct
    19921 ccttggtctt gtgtcaaaaa atccaagatc aaacgaaaag tcgttgtctt cccagccccg
    19981 ttttggccaa ttagccccat gatttttcca tcggggattt ggaaagagac atgatcgaca
    20041 gctgtgtagt tcccaaaagt tttaacaaga tccttgactt ctaacatttc ttcactcctt
    20101 cttcaagaaa tcacatatat ccttagacac cagacgtaag cgatttatta tttaccaaca
    20161 aaacgtaaac gctctttttg ttgtacataa aatgatagga cactttactt tctttgtaaa
    20221 gtgccctttc ctcattcctg atgtaattta tcaaatacgt tttgtgcgac atttttcggc
    20281 agtccgattt cttgtaattc ttctgtcgtg gctgctgtga tatttttcaa cgatttgaac
    20341 tctttaagca gcattttttt tcgttttggt cctaaccctt caatttcatc taatcgggaa
    20401 gcaaaactgt ttttactgcg tagctgccga tggaaagtga ttgcgaatcg atggacttca
    20461 tcttggattc gctggagtaa gaaaaactct ggtgaatttc gctcaagcgg tactacagcc
    20521 aaatctatac cgaatagcaa ctcatttgtt ttatgtttat cgttttttgc catgccagca
    20581 ataggaatat cgattcctaa ttgattttct aagacatctt ttgccacatc tacttgtcct
    20641 tttcctccat cgatcaagat caaatcaggt aaaggcaacc cttcgcgaat cactcgtgaa
    20701 tatctgcgat agatgacttc tctcattgat gcataatcat ccggtccgtt gactgttttt
    20761 attttatatt tccgatattc ttttcttgcc ggttttccat caatgaatac gaccatcgca
    20821 gccacaggat tcgtccccat gatattagag ttatcaaaag actcgatacg tattggggtc
    20881 gggatattca tcgcgtttcc taaacgttca actgctccga tcgtccgttc ctgttttctg
    20941 gcaatcagat caaaccgttc attcaaagca actgaggcat tcttattcgc caattcaact
    21001 aattttttct tttctcctcg ttttggttgc agcactttcg tagctaacaa agcttctaca
    21061 ctgggcttgt cgatcgtatc aggaatcaag acttctttag gaatgaaatg ctcattttcc
    21121 tgataaaact gaccgaggta agtcaagaaa tcttcttctg cttcgttata gaaaggaaac
    21181 attgaaacat ctcgttcaat tagctttcct tgtcttacga aaaacacttg gacacacatc
    21241 catcctttgt caatcgcata accaaataca tctcgatcca gtaaatcagt atttgtcatt
    21301 ttttggcgag tcatgattgt ctcaatggca cggatctggt ctcggtattc tgcagctttt
    21361 tcaaactcca tgttttcagc agctttttcc attttctgat ggatctctga ctcgattttt
    21421 tcgtgtcctc cgtttaaaaa ctttttcact tcatcaacga ttttcgtata gactttcgga
    21481 tctacgtcga aataataagg acacagacat tgtcccaaat gatagtaaag acaaggctcc
    21541 ttcgtctgac taggtttgca ttttctcaga ggaaataatc gatcgaggat cttctttgtc
    21601 tcattcgccg caccgacatc gggatatggt ccaaaataca gtgctttgtc ttttagtact
    21661 ttacgagtaa tcaccaaacg gggatatttt tcattcgtta tcttaaggaa aggataggtt
    21721 ttatcatcct ttaacataat gttgtattta ggatcatttt tctttatcag attgatctct
    21781 aagagcaatg cttcgatatt cgattctgta acgatgtatt caaagtcttc gatttcacta
    21841 acaagccgtt ccgttttcgt attatggctg ccagtaaaat atgagcggac acgatttttt
    21901 aatattttgg ctttgccgac ataaatgatc gttccatttt tatctttcat caagtaacag
    21961 ccgggctgat caggaagtaa agctaatttg tttttgattc gttcgttcat ctggtactcc
    22021 ccttcatatt caattaaagt tattatagca tgtctgtcaa aaaaacaatc cagcctgaca
    22081 acgtaattat actcaaaaaa tattaatttg aataacctta actcaaccgc aaaaaaaccg
    22141 aggacggaac tggattcagt cccaccctca gcttattttt gctgtaagtt tttataaata
    22201 ttgatcgatc atttgacgta gttgttcttt tgaatgaaca ccaacagctt tttctactac
    22261 ttgaccatct tttttcaaca ttaatgttgg aatgctcatg ataccgaatt gttgaggagt
    22321 ttctggattt tcatccacat ccattttagc aattctgaat tcttcttcat catattcttg
    22381 ttccaactga tccaaaatcg gtgcttgcat acgacatgga ccacaccaag ttgcccaaaa
    22441 atcaatcaat acaagtcctt tatctgtttc ttcattaaat gtcttatctg taattacttg
    22501 tgacatatca aagacctcca tttttaaaat ctatgattag tatagcattt ctatacttgg
    22561 atagcgaacc atctgcttac ctttagtaag ctttacttaa atttaacaat tgtcgcacca
    22621 tttccgcctt ggtttgccgg tgcaaactca aagcttttga cgctccgatg gtttttaaga
    22681 taatcagtaa ttcccttgcg aagtgcgcct gttccttttc cgtggacaat agtcacttga
    22741 ggataaccag ctagaatggc agaatccaaa tattgatcta cctcacttag cgcttcttcg
    22801 tatcgttttc ctcgaaggtc caattgattc ggcacgtgac tactagattc agatcgtaca
    22861 gcatggataa ctcgttgtgt cggctctttt tgaggagcaa caggcgtcag ctcgtcttcg
    22921 gacacattca tttttaatat accgatttct acttgccact gattcccgtt tttacgtaaa
    22981 agcgtccctc tttggccgta agtcgtaacc aacacttcgt ctcccggttt caacgttttt
    23041 tgttctttcg ccttcttcaa tactttattt ttcttcaaag tttcttcttg atgtagattt
    23101 gctaattggg tctttgcatc gatcaactga tgctctttca catttccttg cccaatctgc
    23161 tgttgcattt tacgaatatc agcaatgatt ttttctgctt tttcttccgc ctctgacacg
    23221 acttcgtttg cttttttctt tgctttttcc atttcttttt cacgttcttc aaagaaatag
    23281 ctgtaagctt ctttcaaatc atcgtgaagt tcttgtgcct cagaaacaaa atgacgcatt
    23341 tccagatatt cggtctctgc cattttccgg cgattctcta aatctgtgat catttcgttt
    23401 aaatcttggc tctcatcatt catcaactgc ttcgcttcat caataacttc tgtatcaaga
    23461 cctaatcggc tagagatttc aaacgcattg cttcgtccag gaacgccaat cagcaaacga
    23521 tacgttggac ttagtgtatc cacatcgaac tccatgctgg cattaatcgt atttgcccga
    23581 ttgtatccat aaactttcaa ttcaggataa tgcgttgttg ccatcacata agcagacttt
    23641 ttaccaagat catctaagat tgcgattgct agagcagcac cttcttgcgg atctgttcct
    23701 gcaccgagct cgtcaaataa taccagactt ttttcattga cttttgataa aatatctaca
    23761 gtgttcgtca tatgagaaga aaaggtcgat agactttgct caatcgactg ttcgtctcct
    23821 atatccgcaa atacttcctc aaaaataccg atttgacttt cttcacctgc aggaatcggt
    23881 aatcctgctt gccccatcag ttgtaacaga cctaaagtct tcaacgtgat cgttttccca
    23941 cctgtgttag gtcctgtaat gacgatggct tgatagtctt ttccgattgt gatgtcatta
    24001 gaaactactt tttcctgatc gatcagtgga tgtcttgctt gtttcaagac gacatgattg
    24061 tcttcactga ttcccggcac gatggctttt acttctttac caaatcgtgc ttttgcattc
    24121 atcagatcca ttttaccaat cacataagca ttgtggatga tttcttgacg atggggaaca
    24181 agttcagcag aaagttcact taaaatacgt tgaatctcat ttcgttcagc gatttggtat
    24241 tgacgcaaac gattattcaa atccaccact tgttttggtt caataaataa agtctgtcct
    24301 gaagcacttt gatcgtggac tacaccgcca aatacaccgc ggtattcttg tttgactggg
    24361 ataacgtagc ggtcatttcg catggtgatg atcgcatcac ttaaatactt tgcatttttc
    24421 ccacggacga tcccatctaa ctgttcacga acagcttgtt cacttcgccg aatgttctgt
    24481 cttatgctct ttaactcagg agaagcgtca tcagtcacgc gtccgtcttc atcgattgct
    24541 tcctttaaac ggcggctcaa aacagggatc gtgactaact gatctgccca catatacaaa
    24601 cgtgcaaatt cgatttcact gtcagaaaga tcatcaatga aacgattcaa ttcgcttgtc
    24661 gtagacaata ctctggaaac ttgtgcaagc tccactccat tcaagtctgc tccgatctcg
    24721 atccgtttca tatggggacg gatattttca agtttaggta tagggatccc gcctcgcaga
    24781 cgttgcactt tcaatccatc ctcagtttct tgaagccagt ttgtgatcgt ttgtttctca
    24841 ctcactggta ccaattctgc cagttcttct tttccttgtg cagtcactac aaattgtctg
    24901 accatctgtt tgactttttc aaattccaat gtttcaagga ttcggttatt cattttatca
    24961 ccttatcttt cactatgaaa aaagagctgt gccggacata cgctacgcag ccttcttaaa
    25021 taaactactc tgtacaaaaa acgaaatatt ttccagcact attttcctta attcaaaata
    25081 ttcgttacca aagctcatac atcttgttgg taagaaatgg cgttctctca acgataaaac
    25141 gagcgaaact atgctcgccg aattgatttt ggaccacatc taatggaaca aaggcaagta
    25201 actgcaaaat caaaaatata gtaacgtaag ccatgattag tgacaggatg cctcctgcaa
    25261 tccagtctac ctgtctcaag atcggcacat acgtcaatcc atggacaaaa acccccacaa
    25321 atcgggtaag cagccagcca attagcaaaa taatcagaaa agcagttcct gcataaaaag
    25381 cttcatctag gtgaaaagca aatacctgat caaaaaatgc taactttgat gttggggtga
    25441 cagctgggta tggaatgtat aattccaaat gacttgctaa tggtttgtaa aaatgctggg
    25501 cagcaataaa tgacaataca tatccaatcg cgaatatgat ttgcaaagca aacccgcgac
    25561 gtgctccaga aaaaaacgca attagcaata aaaataaaat cagcaaactc agcatgctac
    25621 gttcctttct cttctaactt ttttaaattt ttcttatttt gataaaagga tcttaattag
    25681 aagatttttg tttaatttgt ccttttcgtt tctcgtttaa aatctgttgt gcttccacat
    25741 gatttttaat ggtatgatct gcttgaccat tttctttcaa tacttcccga gcttcgttct
    25801 cgattgcttc aatgcgtttc acacgatttt caagctctgt aaatttgatc atttttttct
    25861 ttaattctgc tgtttcttct tccagctcca agattctttc ttgtttcttc aattgatccg
    25921 aaagcgcatt gacagccatc aagattgctg cttgttcatt atccatttgt ggtgataatt
    25981 gtttcaattc tgctaactgt tcattgatca gcttcgttac gatatccata tgatgcttgg
    26041 tttcccgtcc gataatagta tatgtttggt tggcaatcac tgctttgtag cgtgtttttt
    26101 cgtgcgccat acgaatcatt tcctcctatt tgatgaaagt tttatttagt gtaccatgaa
    26161 gttggttctt tcaccgttct ccacaaatat ttttcacata cttaactatt atatgataaa
    26221 ctttaaaaaa atgctatgtc tcgcaatctc ttagaaaacg aaaagtcgtg agttgcggta
    26281 tagttttatg tataaaaacg aggagaattt tatgagcaac gtcattatca aagcaacaaa
    26341 cgaccaactt agtcaaatga aagcatacta tcgctcttat ttgttaaata aacagattcc
    26401 ttatactagc tttgctgcaa aaaaagacgg gacgaccatt accgcttata catccggaaa
    26461 agtgatgttt caaggtacga atgcagcaat agaagctgat aaatgggggg aggcacagga
    26521 taaacaagcc aagccagcaa aaacagcctc ttctttgcca aaaaatatca gtcaattatc
    26581 cgttttaggt agtgatgagg tcggaaatgg cagctatttt ggtccgctaa cagtatgtgc
    26641 tgcttatgtg aaacgtgatc agcttgcaga attacgtaaa cttggtgtta gagattcaaa
    26701 agagttaaaa gatagccaaa tcatccagct tgctgacatc ttaaaaaaaa ccatccccta
    26761 taaactgctt gtcttatctc cagaaaaata caatgagatc caaccaaaat acaatgccgt
    26821 tcggatgaaa gtcgctttgc acaatcaagc gatccatttg ctgctaaaaa aaatcgagcc
    26881 agaaaaacca gaagcgattt tgatcgatca gtttacgccg gaagcaaatt ttaaaaaata
    26941 tgcgcgttta gaaaaaaatc aattacaaga aaaactgtac ttcgttacta aaggagaaca
    27001 atatcattta gctgttgctg ctgcttctat catcagtcgt gccagctttt tggaagagtt
    27061 acacaaagca tcagctgaag ctggaatcac ccttccatca ggagctggaa cgaaatctga
    27121 ccaagtagcg gcaaaactat tggagaaagg cggcatgcct atgcttgaaa aatatgccaa
    27181 acttcatttt gccaatacag aaaaagcttt gaagctgcta aaaaaataat ggaactgtga
    27241 caaaagtcat gtcacagtcc cttgttccga ataaacggtg ttctcatgcc aactcctcgg
    27301 tcacaagtca caatagtcat caaacatgag aagctgtttt ttgaaattgc tccttgtgac
    27361 gcggagttaa acggcaggct cacaacctct tccttaaacg gtgttcaaaa gcttgcatct
    27421 gcgataataa gcccggccaa acgaaaaata tgaggagcta tttttgtttg gctgggctta
    27481 tttattactg aaaataagtg gtcaatgctt gtgtcaaact tgcagcaatc tgctgctgat
    27541 aactgtctgt tactaattcc tttaaatcac tatcattatt catataaccc atctcgatta
    27601 aaatagaagg ttgaagattt tctcgaagaa cttgatagtt cccagtggag attcctcttg
    27661 aatccagagg cagatcagtg aaggagtcag caattgtctg tgctaatgtt tcctcttgtc
    27721 catagtaata atatgtcgtg attccagttg cttcattcgc atattccgta gagtctgcgt
    27781 gtaaactgat aaagacatct gccttttttt cttcactgta gtcgcatata tctccaagct
    27841 gtactaattc atctgtagta tgggtcaaat aaaccgttgc tccagcatcc tctagcgcct
    27901 tttttacttt tatggctgta cttaatgtta tatctttttc ttctgtttgt tcatcattgc
    27961 ttaatgcccc agtatcattt ccgccatgcc caggatctaa tacaatcact gcatcagata
    28021 gctcttccgg ttttgtttgt atattctttg tgactttggt tccatcttcg agggctaaat
    28081 atccagtata gccatcattt gtcttgatct gataagcatt ttttgtttca gaaagaaact
    28141 ccgccagctc tccgccgttt atagttgcaa gtggggtagt tagcgagtca tctgtatata
    28201 gtgtacggtc attttttccg attttgatta atgtctcttg ttctgtatca tcaaatgatt
    28261 cctttgtctt tgtaaccgta ctgttcgtac tgctgaccgt ttgtccaact atcttttttt
    28321 gaccaaaaac atctatttga aaacagataa taatgataat gattgcaaat acaaaagctc
    28381 caattatttt tttcattctt gactctcacc tcgtagatcc agactaaggg tcaaaactta
    28441 aaatcagctt aagtacgcaa aaaaggggct gtaaaagata taaccgtaga aaataacatt
    28501 actgctaaaa tgattttttt catttttggc atatcctgaa atctcctttt gactattcgt
    28561 ggtgattcat ctacccaata aatagtttcc ttcattctac aaacaattaa tttcttcgtt
    28621 attaaattaa aacacttcct ggaacaccga cataataaat aaaaatatac cctgataatc
    28681 atgagagaat aacaaatttg tatttatgaa aaactaccta tataaaaaaa acaagatata
    28741 acgatcttcg tcatatcttg cttcttcacc taactatttt tctccctata taacagcttt
    28801 acgcttctcc taatacacca ttcaaatata aatcgatcaa ttgcgccaca tttagcggtt
    28861 cttccacagg tcttttcgac cgagtgatgt aaggtgctaa cactaagaaa aaatgccttg
    28921 ctgcgatttc ttttgaaatc ccatttctta gcacagattg gtttgctgaa aagatttctt
    28981 caaaaggttc acgataattt ttcttccata gaaagaaaag atgatctctt gtttcctttg
    29041 aaagattgct ttcaagatcg tgaagcatca gaaacaaatc gaccagatgt gtctcaatca
    29101 aaaactgcgc catttttgtc aaggttactt gaaatcccgt ttcgcttgtt tgaacgattt
    29161 ctctcaaagc ttttccaaca tcttttaagt ggttttctaa aactgccgta tatagttttt
    29221 ctttatcacc gaaataatga tagagattgg gttgggtgat cccaactttt tgtgcgatct
    29281 ctcttgttga agtgccgaga tatcccttgg acataaacaa gtcagtcgct tctttcaaaa
    29341 ttttttgctg tgtatctttg ttgtatcgat ggaccatttt tccacctgct ttttggttat
    29401 tctttttctt tcaatacacc atcttccatc ataaatattc tatcgcattt gtcaatcagc
    29461 cgtgtatcgt gagtaaccat gatcgttgct ttatttttgt cttttgattc ttttgccaag
    29521 atatcgacta cttctcgtgc cttttctgaa tccaaactag cagttggttc atctgctaga
    29581 ataatggacg gatcattgta caatgcacga gcgattgcga ccctttgccg ttctccacca
    29641 gatagttctt ctggatactt gttgatcaac ttatccacgc caagctgctc aaataattct
    29701 tttgcttctt tttgacgatg ttcatgtttg atcttatcta ctaataataa ctgctttttt
    29761 actgtcagaa aaggaaccag attggaagct tgcaaaataa agccaatttc tttaaaacgt
    29821 agtttaacgc gttcactttc tttttgatta ctgaattctt gatcattgat aaatacagag
    29881 ccactgctag gcgtctgcaa tccgcctgcc aaagtcaaaa aagtactttt acctgaacca
    29941 gaaggaccga tgattgcaac aaattcccct ttatcgatac tcatggttgt ttctttcaat
    30001 gctttaacta cttggtcgcc atcttggaaa cttttttcta cttctttaaa ttctattgct
    30061 ttcatgctct tcctccttct tatccaattg ccttcaacgg atcgattttt acgattgtcc
    30121 gaacagaaaa tagtgcgcct aacacagcta ctaccagcat caacaagcta atgacgccaa
    30181 aaaacagcca attgctttgg aatggaaccg catcaggtag aacaagggat gttcccactg
    30241 ttcctaatag accaagaaga ataccaacaa atgataaaat gaatgtttgt gccactacag
    30301 aacgcgcaat aaatcctcct gtgatccctt gtgctttcat tacaccaaag atattaatct
    30361 tttgcatcgt cagtacataa atgaaaatcc cgatcacaat agccgcaata acgatcaaaa
    30421 atccgatcat aaatccaaaa gtcaatactt gcgcattata tccaggtaat tcattgatga
    30481 atttagaaat tttgatctgt tctaaatctt caggtaaatt actgatttta cctctgacaa
    30541 ctattgcgtt aatccgtgca ttttcacttg tatcttcttt ttcgaagcgg atctcttggt
    30601 aagcattgat ggttgtatag agaactggtg agacattgaa tttggcatga tccgtaaagc
    30661 cagttagttt aaacgtcttg tcactaccag ataacttaac tgtatctcct acggctagac
    30721 catattcttc tttcaaacta atatcgccta ctgcctcatc atcgttatca aaagcttttc
    30781 cttcaacaag attgggcatg atgaattgat ttttatcgat accgaagaag ctaacattga
    30841 tttttccttc ttctgtactg tctttactag tcacgactcc aggtgtctgg gcaagatacg
    30901 ccactttccc accttcgact tcttctgcta tcttcttagt aatcatggac atccctagat
    30961 ttgaatttgc atctttcgaa agcacaatcg aatctgcctc ccacttgtcg actgctgttc
    31021 gattatcttg agctaagcca taagctaacc cagtcaaaaa aaataccagg taggcgatca
    31081 aaaacatcac ccctgcaact aacgcataac gtaactttga atgcataatt tcatttaatg
    31141 ctaaaaacat ttaactcctc ctcctgaaat aatcatttta tacaacaatt ttatcacttg
    31201 ataaattttt ggcgaatatt atgctcaaaa aattcttccg ctatttcatt atatgaattt
    31261 tttattctcg attgattaat atttattata tccccacaca ataaaagacc gtgatatttc
    31321 tcacagtctt ttatctactc tattgctatt tgctctctta gctagtactt taaaagctaa
    31381 ctcattgagg tagtgaaaac gagaggtgtg ttcagacaga aatccaaaat cctcaactgc
    31441 tagctgtgga atcgtagttt tgtgtttcac gatatccgca agcaggttca aatctgataa
    31501 taagaattct tggcttatca gctgtccgcc aattatttct aatgtatccg gatggtagat
    31561 cagctttgca tttactgttt tgttttcttc atcgtattgt ggaaatagat caaattctcc
    31621 tgaacacgaa ccggtatttt gttccaagaa tggcgcttca tcttctgtca gccctacagt
    31681 tcctaaaaag tagtctataa tgactgctgc tgttatcttt tgtctgaggt cgtaagcggt
    31741 tggctgacca ctcaaagtta gcgctactgc tcttgccata tgtacagctc gagtaactaa
    31801 aggtaaaaag agatgccgtt tatttttgtc aaaactgact gggacgatat ctccaatcgc
    31861 atagatgtcc ggatcacttg tctgcagata ttcattgact atcacagtct catcctcata
    31921 caaagccact ttttctttta acaatgtcgt attaggacga gtttgggcag aaaaaatgac
    31981 catatctgcc tttattgctt gagatagaag ttgtacggat actactttct cttctgattt
    32041 tttccaatcg atcaagaatt catttggata aaaattgatt tgcttagttt gcagctgatt
    32101 ttgaaaactg ttgatcatat ccttatcgaa atatcttgat aaaacattcg gcatataatc
    32161 aactagatga ataatgtatc ctttatttct caaagcatct gctaattcca atccaatata
    32221 accagcaccg aagatcacta cttcttttgc ttcttttaaa gcggcaagta cttgcttaga
    32281 ttgcactaga tttttatagg tgtagacatt ttcagcttca atttgtttat acaaggtgac
    32341 aggagaggaa cctgttgcta cgattaattt atcataggtt atggtctcgt tttttccttc
    32401 tttggatgcg aggatgagct gatgtttgtc tggatcaagt tcagttactc tccattcggt
    32461 gatcagtttt gccccacttt cttgaagagt ccgcatgtta tgggcaactt cagctaaact
    32521 acgtatcttt ccttttaaat aaaggttgat tccatttgaa acatagccta gtccatcttt
    32581 atgatcttca tcgatcagta aaacttctgc tttcggttga agttttctta gatttagggc
    32641 agctgtgatg cctgcatggg aagcaccaat gatcacgatt ttcatgtttt attcatcctt
    32701 aaattcaatt tttctaaata acattctttt aaaaattggt tcaaataggg gaaatcataa
    32761 ttatattcgt tgctagtgaa tacaaaaact ttagcggact tctgtgacgg gtactctttc
    32821 aattggctag tcaaaatgat atcatactgc ttttctttct cgtattcgac taaatcatat
    32881 ttgatcgtat tcagcaattg ttcctggatg atttctttca cgatatccgc cattagcctt
    32941 tcataaggaa gatcataagc aatttgcaga cgtaattcta actgcttgat cagcgtccgc
    33001 aaaatagatg catagcgagc aaataattca aagcgggcat tttcctcgtc tacttcagta
    33061 aaatcaacaa tagcaaatgt ttgtctgacc aatctttcac ataaaaccag gaattgttta
    33121 tcttctactt cagttaaccg ctgttttaat ccttcttggc caaaaatatt catccatcct
    33181 ctaaaatagg caaaatgagc gtgattttgc atcactgtca acgcaatctt ttgcgaaatc
    33241 tcttctggaa aaacataaaa agagaaatat tcttctatcg attgtttaaa cgttcgattc
    33301 aattgagcta ctacgtcgtc tttgtatttt tcgcttatca aaaactcctg gacatgcgag
    33361 ttatgtgtat ctaatgtaaa gttactgatc atgaaaagat aaaaaaccaa cgtttcattt
    33421 tgattccaag gaaaggcata ttgaaagaag taacgggtca aaaatgtatg gaggtccaat
    33481 aaaaattgtg tcgtttgaaa caatccaaca ggaagattgc tataatctgg tttggatttt
    33541 ttcgtacagc gcattcgctt cttcataatg gaaagccata tttcaaattt caatcgtcct
    33601 tcttctgtaa tagtaaaact aaactctttt tgcagcagat ctaaaaaagt gtttcctgat
    33661 aaatcactgt attctttttt gttttcaaga taaggacgtc caaaccaaaa taattggaaa
    33721 taaaaataac aaatttgact ttctggaccg gtcagccgcc cgctttttat tttcagatga
    33781 aactcattta aagaatcatt taattccttc actctgcgag acaaagtagc cgaactgata
    33841 ttaagttcca tgacaagttt ctgccgatca aatgagccat tttccaacag ataaagaagt
    33901 atctgatatt ttgtagaata gcgcaagtag caatgataat aaacatcgac tgctgctata
    33961 tttccatgtc tgattaataa aatattccct tcttggataa caatttccaa ttgtttgata
    34021 ttttccaagt tagcttgtaa ataaaacaga tcttctttca aggtagcccg atcaactgat
    34081 aagcgggtaa gtacgttatt aacggaaatc tctccttttt cctctaataa aagttggaaa
    34141 agtttgattt gccgttgttc atttttttca agcaaactga aaagttccaa gtccactcct
    34201 ccaagcattt ctgattttaa cagcagaagt ttccttctca tccttgaaaa agaggatctg
    34261 tgacagttat cacagatcca tacaaattct aatcacttag ctggttggcc cagctgtcag
    34321 ttcccatgtg accatgcctt gatacgttgc gccaggttga gcattcgtac tgctatttac
    34381 ctctaagagt aaaccatcgg tatcgggaaa gtcaacgaga acctctcctt tagctgttcc
    34441 atcactctca taaatcaacg tgttttgacc ttgctgaatc aattgttttg atccagaatg
    34501 attgaagtat aattttgttc cgcttaattc ttgaccttga tcattcttaa ataaagaagt
    34561 caatgtccct gtcagttgcc aaggagacgt gcttggaagc cgagtatccc gcacatcaaa
    34621 agaaaaatcg ccttttgctt cataataact tgtcttcaac ggtttgggga gatcgttacc
    34681 aaatgtaaaa tcatctggta cattaactaa tgttaattct tgtttgggga caagaattgt
    34741 tttagcagat gtttggacaa ctgggttagg aagcttagca ccatctgcta atgtaatatt
    34801 gctggaaagt acagctgcct ttgtcagtat gctgacggat tgtacagaag tatctacagt
    34861 atttaattga tagttgtaag taagatgaat ggtatctcct attttgctca atagatctgc
    34921 tgggacagaa actccttgtt gaatgccggt atctgcgata gttgtaccat ttaattttaa
    34981 ggaaccattg atataagtag tattttcagg aagtgagatc gtgatttttt tgtcggttat
    35041 cgcatcccca gattttgtta acgtgaatgt cacattttct tgaatcgtat ctcctgatag
    35101 agcagacagg ggatctcctg tctcaggttg tctgctaagg ttttttagct gactatctgc
    35161 actcacagat ggaaaattag ccactgttat ttgaggaaga gtggtgattc cagcttgttc
    35221 agactgccat ttgtacgcaa aagacggata catgttagta agtacatcgt ccaccaagcg
    35281 ataatcaaaa taatattgcc ctgaagccaa tgcaggtagt gtagaagtag ctgtatttac
    35341 acccccgtta tttgattgga tcgtttggaa aagttgatct gtccatcctg tcgctaattt
    35401 ttgggttcct ttcgaataaa gcctgtaatg gatcgaaccc ttttttagtt cagttgctga
    35461 ccaattggcc gtgacttggt acgatgcaga agaaaggagc tttccccact gactatcggc
    35521 tgttaagttt gttggtaaaa ccgttccgtc tagcttgtac tgctccaata cctttaaagc
    35581 aacaggagaa agcaatccgc cttgcgcatc tttcccactg tacacgatat tggctgtctg
    35641 attcaatcca cttgtgcttg ctggagtatg agtcagtatt gctccttgtg taacgttttt
    35701 tcctgtaaaa tagttgacta cgcgatcaaa gcgactaaat ggcaactgat caaaacgtcc
    35761 ttcagtcagc cccatcgtca atgtccgact attggtagag cctggaaggt tctggttatt
    35821 tccatccacg tattctgtgg tatcagcaaa tgtattatat tttcctgttg aatcacttgt
    35881 tgagatgtaa ctattccacg tatttatctc tgcacttgca gaaaatgcat atgctcctgg
    35941 attcaagttt ccgccagtta atttaggata aaatctacct gcagctggag ctaaaatcga
    36001 attgaacata cgatcttgga taatattatt cgaatcataa aaatcaacag aaaaaacggc
    36061 ctttttagac atagaaggtt gtaatttacc cttggtcaaa attttgtttg gactcgtatc
    36121 atatttatct ccgttttctg tcatcttcgc gacattagct gtaacatcaa attgaagcgg
    36181 gatatcgtcc acgttgaatt cgcctcgcgt aataatagca ataatatctg ccaatagagt
    36241 atttgtatcc cacgacccca tcccaaaacg caaggtatgg cttcctgctg ataataaact
    36301 accgctagta accttgatgg gggcaccggc aatatacaag taggcgttgt tccagtcaat
    36361 tgcttttaat acatcactgc ttgatacatg ttccggcaaa ttgatgatcg ccacaaatgc
    36421 aaatccttgt gcagtgatat tcaccaaatc aagtacattt gttagtttca catggctttc
    36481 ccaatgaaaa cggaccgtgc cacctttcca aggatcattt gaaccatcgt tcaaataagt
    36541 agcagtcaat ttaggcaatt ggttagcccc agttagttgg acaagcttcc cgccattgac
    36601 tgcactacgt ccaccatttg gaggtacgat attttcatac gtgtatggat cataagaaat
    36661 ggcaggaggc gttgctccaa cagcttctgc cgaaggtgaa aagataaata tacttaaaac
    36721 aaaaagcgaa gtaaaaaaga aggagcgaaa aaatgaaaat ttattttgta gcaacatgtt
    36781 catcctcctt ttcctttctt ctccataaca acaaccacgc aagaagccat aattctatac
    36841 caatgatcaa ataaagaaaa cggatctttt cttcattcgt ctccgggaat acgccatgtt
    36901 gattagattc tttataaatc ggtagctgtg tctgctgttt tgatgcgcca ttgactgaac
    36961 cacttggatg cggaactgga cttagatcat aaaatgtaat cgtacctgaa cttttggtat
    37021 ctgcttggac tggctcttgc cagctgaaga acagcaaact tgcaataatc cctcccaata
    37081 agatcgatgt tttcaacgaa atcacctcat catgttgttt ctcctttttt ctttttcttg
    37141 tggacccaca aaaacagcaa aatcaaccat aacactagaa ctgcagcaac caatcctgca
    37201 taaagccatg ggaaagattg ttcttgtact gcaaaaacgg aattttcatt tactttttgt
    37261 gctttttctt ttttgatcgt aaagttttgt gtaaatcgcc attcattact gtcgcctgat
    37321 tttgctatga tttctgcgcg gtaatcgccg gcttttgctt tatcaccagc taaatcaaga
    37381 ttcaagtgaa aattcgaatt tggtgcaact aaaaattcat tagacgtatt ttcaatataa
    37441 agctgatttt cataaaagat cttgctcgta aatatcaaat tgctgataat cctaggctga
    37501 ggattttgga aacgaagctg aacagttggc tttgcgttga cctcgtccaa atctcctgat
    37561 aaaagtttca gatccggttc tatcgtctct tgactttctt gtaaaacgac tgcgagatta
    37621 taagcaatac gatttttgat ttgtgctcct tctgtagcat tttctgtttc agcttcttct
    37681 ttaggtgaaa catgaatacc cgctaataca cgtcccttaa agctttttgc tgggattttc
    37741 acttctatag gtatagttgt ttctgcatgt gctgatacat tgatttcctt tttcgcaatg
    37801 agcaaaacgt cacggacatc aaacggcaat gtctcatcta acgttgggtt tttttgacta
    37861 taatcgatcg ttccaccatc actcgttacc gccggattga cagagacctc aaatgttcgt
    37921 tcttcatctg aagaattgct gataattact tctagtgtct gattttgttc cggtgccact
    37981 aataaatcaa aataaccgat tgctttatct atttggttct ctggaaatac cggtttgatt
    38041 ccaaagtctc ctgctgaatc ctttgcttgg ctgattgacg gaaaaatgaa aaatagactt
    38101 aaaatagaaa aaaacgaaac aaacagtcgt ttactttgat tcattgtcca ccacatcctt
    38161 tcaacaacaa ctgcggtaaa aaatccttca cctatagtat tttcaccgca gtttgttgaa
    38221 tttatttcat actctatgct actgggccag ccacgaggtt ccaagtcaaa tcagccgtga
    38281 atgttccagc tgctgctttc ggcactttca gtgtgatatt tgctggatca taaacagaaa
    38341 gccatgttcc cagaccttga tcttttgctg ctgtaaatat tggtgtcgct gcacttgctt
    38401 tactcaaccc agttacagtt tgactagttg gtccagtgga ttcgttatct gacgtacttt
    38461 taacagtgga tgttccaaaa tctaattcag cgccttgcaa aacttgtgaa ccgtttacaa
    38521 aatctgaaac cgaaactgtc acgttccacc cttgtgcttg gccatctgca cctacacctc
    38581 gacgatctga tacttggaga taaggtgtat cgttttttga agcgtctact tgatacgttt
    38641 ttgttccgct ttcaatctcg tgtgtaccaa atggcaattc aggaactaca tccaatgtta
    38701 aagaacctgt ctggccagtt gctggatttt ccggatctgc tggctctact ggttttgaag
    38761 gatcagtagg gttaagaggc tcaacggtat ttgttggttc agtaaaggta atatctcctt
    38821 ttgaagtcgc ttgaccctca gcaaaagctg gtgttgccaa gccgcctaga agaagtgttg
    38881 aaagtaataa tgtcccaatc atgttctttt tcataataaa tcactccttt ttcttagtga
    38941 cctaagtata gtagagacag tatgcaaaaa atcctcatga attcatccgc ttacttgaaa
    39001 ttatgaccct ttttgtataa aagagaaaaa aacaataaaa tcgtttacat gaatattctt
    39061 ccttttttat taagtatgaa aaaatatttc aattttattt tttcgtttca aattattcta
    39121 ttagtgacat ccttgaacta taaaaatagg agtacggcat catctgccgc actcctattt
    39181 ttttcgtcat ttatttctta aataaaacga ttctcacgca attttatttt tttgatatct
    39241 tctactgttt gtgttccagc taattgcatg accatttcca attctgtttt aaagaaatca
    39301 aacacttgat ggactcctgt acttcctcct aaagacaatc cataaataac gggtctgcca
    39361 atagcaacaa gatcggcacc tgatgcgatt gctttgaaaa catgttgtcc acgtcgtaca
    39421 ccgctgtcaa acacgattgg tacacgttta tctactgctt ctgccacata ttgcaacgaa
    39481 tcaaacgcag caggcccccc atctaattga cggccaccat ggttagatac ccaaattcca
    39541 ccagcaccag attctaatga tcgatagaca tcttcttctg attgaacacc tttcacgtag
    39601 actggcaaat cagaatgagc agcgataaat tctacatctt ttggactaag tttttgtttg
    39661 gaagatttat atacagcatc catcgtttgg cctactcctg attgataagc ctgaacgatc
    39721 ggcattggca gcgggaaggt aaacccgttt ctgcggtctg tttcacggtt tccgccaact
    39781 gttgcatccg ctgtcaatac gattgctttt gctccattac gcttggccac ttcaagaata
    39841 tccaaattga ttccattatc tttgctcata taaaattgaa accattgcgg tgctttctcc
    39901 ccgcctgctt ctcttatctc ttctaaagta caagaagcgt aagaacttgc tgtatagatc
    39961 gtcccaaaat ctgctacacc ttttgcagaa gctttctccg ccttcacatg agctaatcca
    40021 tgagcagcaa ctggtgccat gatgattggt gcagtcagca tttcttcgtc aaaatgtgta
    40081 gttgtatcgg gtaattctac atctcttaat acatgaggaa taatcaaacg atgattgaat
    40141 gcccgttcat tttcttgata agtaaataag tcgccagcac cactgctgat gtaaccataa
    40201 ccaccagctg gaatcacttg tgaagccgcg atttctaaat cttccatatt gataaaatct
    40261 actattcctt catttgtacc tgcttgatat gttttttcca tctcaatgcc ttctctctat
    40321 aaaatttgaa tgatgaacaa tatgatagcg tttacacttt ttatattact cttcgacatt
    40381 gatacaggca aataatctgt ttacatttca gccattccag atgtcactac tctggaagaa
    40441 atgattgtaa taaaaataga taaaaaaccg atgggacttt gacaaaagta gtgtcaaagt
    40501 cccttttttt gaataaacgg tgttcaaaag ccattttctc ggtattaagt caaatttatg
    40561 caaaaatgtg gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt
    40621 ttcacaacct ctcgataaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    40681 tggcaaaata tgaggaacta ttttgccatt tgtctctcta atactcaggt cagaacgttg
    40741 acttcacagt ctcttcctta aacggtgttc aaaaacttgc atctgcggta ataagcccaa
    40801 ccaaacgaaa aataggagga gctatttttg tttggctgtt cttattactt gatgcagggc
    40861 aggtttttca cgacctctga ttcacggtgt ttctttttca tcaacatttt tacgaaatac
    40921 tgtggaagac tattgaaata agtgtggatt gtttctttgt gtttcaatcg tttcttgcca
    40981 ttcttcattt aattttggat taccgttttc ttccttgaac tcataaggtc ctaattcaaa
    41041 aatcccagac agtatttgat tcacgatttc atatagttca gtgtgatcag acacatgatt
    41101 cttgaagatc atctcattat caccacgttt gaacctcaca ttcgggctct catgatgaac
    41161 ctctatgcat ttttctcctt tttttaactg acggacttct gaaaacatct cataaatatc
    41221 ttctccagta aaaccttcag caagcgccag actgtccaca agaccgccta ctgtcagttc
    41281 agagattatt gcttgattgg aatctaattt taatgtatag cttgtcgctt ctactacgcc
    41341 acatgcattg caaccgcctt ctgatagttc gctttttcta atcaattgaa cttctttcat
    41401 tttctcttcc tcctcttaat tttctactta tgtattttta tcacctgaca taggtgactc
    41461 ctatcaacgc tatcatgtgc ttttttcctc agaaatccta tttatccatt ccatctatcc
    41521 cttattcttc tacttttctt tctctagcat ataagagata cgcatagtat tcaagcaagg
    41581 attgtcgata taaaaagaac aaatactgct attttgattt cttttggcta tattacatat
    41641 aaataaaatt tatcatacct gctctttttg actatatcat catctgactt ctatacttcg
    41701 tttgtattaa aacttaggag gaatcattca tgcttacagg gttaaactta ttaaataatc
    41761 cttttctaaa taaaggaaca gcttttacaa aagaagaacg ggcaaaatat ggaatcactg
    41821 gtatgcttcc aagtactgtc caaacactgg aacaacaatc tgttcaagct tatggtcaat
    41881 acttaagcaa acaaacagat ttggaaaaac gtatcttctt aatgaatcta ttcaatacga
    41941 atcggacatt gttttataaa ttgatgggcg aacatttagt tgaattcatg cctgtcgttt
    42001 atgatcctgt cgttgcggat tcaatcgaac aatacaacga aattttcttg aaaccgcaag
    42061 atgctgcatt tctttcaatc gacgaaccag aaaacatcaa agcaagtttg aagaacgcgg
    42121 cagatggacg agacattcgt ttgattgttg tgactgatgc agaaggaatc ttaggtatgg
    42181 gcgactgggg tgtgaacggt gttgacatcg ctatcggcaa attgatggtc tatactgctg
    42241 ctgctggtat taatccagca caagttttgc ctgtatcgat cgacgctggt actaataatg
    42301 aagaattatt gaataatccc ttatacttag gcaatcgtca tgctcgtgta gaaggcgaaa
    42361 cttactatga attcatcgat caattcgttc aatcagctac cgaattattc ccagaattgt
    42421 tattgcattg ggaagatttt ggacgaggaa atgctgcagc gatcttagaa aaatacgaag
    42481 atcaaatcac tactttcaac gacgatatcc aaggtacagg aattgttgtc ctagcaggtg
    42541 tattaggcgg attgaatata tccggtgaac aattgaaaga tcaaataatt ttgacatttg
    42601 gtgctggtac tgctggtgtg ggtatcgcaa acatcctttt agatgagatg atccgtcaag
    42661 gtgtacctga agaagaagca cgccaacatt tctatcaagt agataaacaa ggtttattgt
    42721 ttgaagatac agaaggattg actcctggtc aaatcccatt cgctcgcaaa cgctcagatt
    42781 tcactaatgc tgatgaattg acaaacttag aagcagttgt aaaagcgatc catccgacaa
    42841 tcatgattgg tacttctacc caacctggag cattcactga agaaatcgtg aaagaaatgg
    42901 ctgctcatac accacgtccg atcatcatgc ctttgtctaa tccaacaaaa ttggcagaag
    42961 caaaagcaaa agatttaata gaatggacgg acggaaaagc attagttgga acaggtatcc
    43021 ctgctgctga tgttgaatat aatggtgtaa cttaccaaat cggtcaagca aataatgctt
    43081 tgatgtaccc aggtttagga cttggtttga ttgcttcaac agctacacga gtaaatgctg
    43141 aaatcatttc tcaagctagt cgagcattag gcggaatcgt tgatgtaaca aaaccaggag
    43201 cagctatctt gcctccagta gcaaaaatca ctgaattttc tcaaacgatt gctgaaactg
    43261 tcgcaaaatc agttgtcgca caaaacttga atcgtgaaga aatcacggat atcaaagaag
    43321 cagttgaatc tgctaaatgg gttcctgaat ataaatcttt agaagattaa gatcgttata
    43381 gtaaaagaac atacagaaac tttgtatgac gtctaaaaag aaaaaagcga ctgcggcaaa
    43441 acagcggcca gccaactcct gctcttttgt cgcttttctt tggctttttt catatgatac
    43501 agaataagaa aggatctgta aaaatggcac aaaaaacaac aactgcaact gcagttgagg
    43561 aaaagaaaaa agaaggtttt tggtccacaa aaatcaccgg cgtaagtttg ccactttatt
    43621 tgatcatggt ccttgtcctg atcattgcaa tggctttagg gaaattaccg acgaatatga
    43681 ttggaccaat cgcagttttg gttattttcg gtaatttatt tcattttatc gggacaaaaa
    43741 tccctatcgt caaaagttat ttgggtggtg gttccgtttt tgcgatcttc gcttctgctg
    43801 cgattgctac atttgggatc ttacctgaat atgtagtgaa atccacagaa aactttgtca
    43861 gcaatatggg cttttgggac ttttatattg ctgccttgat tactggtagc atccttggta
    43921 tgaaccgtaa tctattgatg aaagcttctg ttcgttttat tcccgttgca cttatttcaa
    43981 tggtcgtctc cttttttgcc gtaggactcg tgggcatgct tatcggaaat ggttttgcaa
    44041 attccgtttt atacatctca ttacctgcga tggctggtgg tgttggagcc ggagccgttc
    44101 ctttatcaac gatttatgca aatgttttag gtacggatgc ttcttctatc atttcccgcc
    44161 tgattcctgc gacagcaatg acaaatgtct tagctatcat cggtgcagca ttagttgctc
    44221 gtgctggaca atcaatgcca aaattcaacg gcaatggtaa attaatggaa aaaggcgatc
    44281 ttggcgatgg aaaacctcga actgtgaaac cttccattcc acagttaggt gttggtttga
    44341 tggtatcatt gactttcttc atcttaggac aaattggtaa ctattttgtt cctaaagtcc
    44401 atgcttacgc atttatgatt attatcgttg tcatctgtaa aatcgccaac ctattaccag
    44461 agtattatga agatgcagct atcatgttca ataacttgat tgtcaaaaac ttgacagcag
    44521 ctgttcttgc cggtatcggt attgcgttgc tgaatctgaa tgtattagct tctgctttga
    44581 catggcaatt tgttgtctta tgtctgacaa gtgttatcgc gatttcagtt gtttcaggat
    44641 ttgtcggtcg tttgtttggt ttatatccaa ttgaatcaac tattactgct ggcttatgca
    44701 acaactcgat gggcggaaca ggaaatgtag ccgtcttatc tgcagctaat cggatggaac
    44761 ttattgcttt tgctcaaatg ggcaatcgac ttggtggtgc catcgttttg atcatctctg
    44821 gtttcttgat gcaattactt tcttagtcaa aaaaacaaaa atacctgatc atcaagtatc
    44881 ggcttggtga tcgggtattt ttttgataaa gatttacagg attttcaaaa atcttttttg
    44941 cattttatcg gaatgataac cgatgtgttc ataaaattgg tgtgcttcta ctctgtattc
    45001 tgcagaatta agccttattg tcgttattcc tcgttttttc gcttcttctt ctacgccagt
    45061 catcaaagcc tttccgatgc ctcttttttc agcatattta gacacagcaa gtgccataat
    45121 attgaacatt ggatcgctaa aaatcgattc ataggactcc gcttgtacat agccagctgc
    45181 ttttttagaa gtaggatctt cataaaccaa gaaaaaattt ttctctggct ccttcagcag
    45241 tttcttcatt tgtctcaccg taacggttaa tggtatatca taccctaatt gatccgcatt
    45301 gatttcacgt agtgcttctg catcttctaa acgcatttcc cgtaacatcc aaatcaccag
    45361 ccaatttctg attttttaaa atgaattttt ttatcatagt atactctttt tttcatttag
    45421 aacaatatgt ttcagtgatt ttgacttgcg ttagtctaga ttctcctaat gtttgtaaga
    45481 tgacaaaggc attgtaacaa ttgaccaaaa gaaccacgag gacaattact tgaaaaataa
    45541 aggtcacttt ttttggagac aaaaccctgc taaatcttgc tccccacaaa cctccaataa
    45601 cagcagcggg gataacataa aacaacatag ataaatcaaa gcgcataaag ctacttgtta
    45661 aagcaatcgt taccaatttt gccagttgag aaaagaaaat cgtagataga gaatatagtg
    45721 ttgcttcttt tattggcaat gcaaacatca gcatcaacaa agaaacattg actggtccac
    45781 caccaatacc taaaaaacta gctaaaaagc ccagaacccc cccacatata aggtaccaag
    45841 tccatgacgt caaatgaaat tttggctgat gatgcttggt gtagaagaac gcaaaaacca
    45901 aggtcaatac cgtcaaaaaa atttggatca gctgcacatg cttctcgttt tcaaataact
    45961 gtaaaaaaac ttcgaataca atgttgccga ctactcctcc aacaacagct ccactagata
    46021 cccaaccgac aatctgccaa ttcagtgatt tcccgcttga tacttgtcgc acagtcgaaa
    46081 caatggacat cgtgaatacc gcaactgttg agtaaaaaga aatccctgca acagaatggg
    46141 cgccgataag atcaagaatc ggtttgatca acacgcctcc acccatcccg gaaatagcgc
    46201 caactgtgtt cgccagaacg atcaccacaa aataaatcag accaatcatc ttgtatttcc
    46261 tttctcttgt ttatatcttt tagcgattgt tactcttttc ttttattata cagtaaaaga
    46321 aacaaacgag gcttcgaaag cttttctact ttttaaggaa atttagtgct aaacgaaaag
    46381 aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagctcct
    46441 cataattttc gtttggttga acttattacc gcagatgcaa gcttttgaac accgtttaag
    46501 aaagaggtcg tgagcctgcc gttcagctcc gagtcacaag gaacaatttc aaaaaacagc
    46561 ttctcatgtt tgttgaatat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
    46621 aaggaagaga ctgtgaagtc aacgttttga cctgattatt agagaaacaa atggcaaaat
    46681 agttcttcat atttcgccgt ttttcgagcg aatgccgagg ggcagctgat tgaacatcgt
    46741 ttatttggaa aaagggattg tgacaagacg tttgtcacaa tccctttttt tatatcttat
    46801 taattcattc ttttgttcta ttcttcttct tccgccatga atgagaaacc catatcaaag
    46861 aactataaag gttatcaaaa cagcgtttat gactaaatga attagagtta tctatcacta
    46921 tttttcaagc gatttaaacc aaatggcata caatatggca tacaaaaact tcaataagcc
    46981 gtgggggttt ttaaatttct tcttgttctt taaaatcaat gagtggagct acataatttg
    47041 aatccacttt ttcaaacgtc actttttgca tcgacgaatg ttttctttcc caagataacg
    47101 taaatagatt tgactctgga cttataaagt ctacttcacc ttctagtatt actttcttat
    47161 gcaaatattc ctctaataaa tatagacttg ctaaagcata caacacattt tccaaatttg
    47221 cttccttata atttgaagaa cgaccatgtt ttactctgtt atatattttc caccaatctg
    47281 gtgtatcttc aggccaccca tctccaaaag gttttagtga agtcaatgtt aaagaattca
    47341 taaccctaac accattatcc aaacacatta attcgctaga tttaataaca gctttaaaat
    47401 cagttatgct tttattgcta ctgctatcaa atccgcaaag ttctttgaaa ataatctcac
    47461 actccgaacc aatcgctagt agtagttttt gatattcaat agagaatgtt ttgaaattat
    47521 tctcatcgag catcacaaaa tctgtggtat taataaactc attttctaaa tgtagataat
    47581 acttccaata aaaatttgta aactctgctt tgtccattaa atcacctctt ttgaattata
    47641 acaaaaaaaa cacgtccaca acagacgtgt tctttgattt ctacacaatc agcttgccaa
    47701 aaccatccaa tcagtcctag catgcctgta ttaaaattga acgttcatca tctatcatct
    47761 ttcttagtcc agcatgtttg caaccacacc tacaattttc agtccaacaa tagatttcga
    47821 ctagctaagt cttgcaaaat tcaggcagct aacccttcat ttactacctt aattatacta
    47881 aatacccaca acgtttacaa gtgtaatcat tctaagaaat ctgtttagct atgatcgttg
    47941 tataatcttt aaacgccgtt ccttcattga ttgaaataat tttataactc ttgtttttcc
    48001 aagctacttt catatcgttt gttagttcat aatcttgatc gtatcgaata ataaacgtca
    48061 acgttccttc aagaatggta cctacactag caagcacgtc ttttagcatt tgtgaacgca
    48121 cattagccca acattcaaat acagtttctt cactatccac catctgccca tcttcatctt
    48181 ttacccgttt tgtcttttta aacttgactc tctcagtcaa ttcatttaca ttcttaatga
    48241 ttggcataat aagcacctct catttgttgt actaatgctt gtaccgttac tggtatccgt
    48301 tcgctgctgg cttcttgacg gttcaaatac caatgttgag taagtaatga caccgccaaa
    48361 tcaaattgct gataattatc catatcttta tccgttgcgc tactatcaat agcacttttt
    48421 atatattcgc ctgctgtatc aatcaattgt tgaataaagt catcatcaat agtgtgatcg
    48481 atccgcatac ttttttttat gctatccaaa attaccattt tatctctcct aatgaaaaaa
    48541 aggcagtggg ataaaccgcc gcccaatatt tttctatact tttggtgtta caactggcgt
    48601 aaactcaata tacactgaag cattttgatc aattttctta taatcgttgc gaacgatcac
    48661 tgcaagtcct tgtgagtagt aatcgaattt ttcccattga gtcgttactt gatttctacg
    48721 agcaacaaag atagattgtg caatatcccc cataatcata gggaatgttc cagctttagg
    48781 attggcaaac aatgtatctg caatcaatac tactggcata ccgaataatg atttaccact
    48841 aggtgctgtc acatcgggtt gtaaaatgta acgtccatct gaatctttca atgtatctag
    48901 gtggtaatat ccgctttggt ttagaattac cattttattt aatgctgggt ctaatgccac
    48961 attgtatagt tgtttcaaat cgtccaacgt agcagccgtt ttcttagtga atgtttttaa
    49021 taaatccatg atatgcttat tgtcagtgtt ttctaccaat ttcgctaact gatctttgac
    49081 ctcttgtaca atattcactg ctgaatcttc cacaacctca tttgataagg caatcttacc
    49141 agcacgagtt tctactttat aatcaactga agtaaacatt tcagcgtcaa tatcaccaat
    49201 ttcagcaagt tcagcttttg ttgctaacac tgcttgttgg ttagttgcta ctggatattt
    49261 accttgtcca tttgatactg tttttactgt tgcatattga gctaagttat aatttgaacg
    49321 tttcaaatca aagacttcac cgattacttc ttcgggaaca actgccgctg catttacagt
    49381 agtgactcca tcacgcactt cgccttgtga acggatatat tcttcatacc cacgcaattc
    49441 tgttttttcg ttatcgatta aagttttttc catgttatta ctctcctttt gtgctttaga
    49501 agtggattct aagctattgt ttgtttgttt tgcttggttg ttactcataa acgattcgta
    49561 agaacgctta tttacttgga catttgatga atcataagcg ggaacggtca cgacactaat
    49621 ttcattaagt gctttgattt tatctattga tcgttcaatt gtgccatctt cttttttgtc
    49681 gaatgaatct aatccaagca cgaacccaaa ggacatagaa tcaacaaccc cttttgagat
    49741 attctcatac acatcatttg aataggtcgt gtcggttagc tctgcttcaa aatgtaatcc
    49801 tgtatcatcg acattcaatt tcaacgtacc tgctttgaca ctagctagtg gctttgaata
    49861 atcgtgtcca tataataaga acacatttga taaatccacc tcttttaatg cttcgggtgt
    49921 aatcacttct acaaagccgc ctaaatcttt tgacggttgc ccgaatttca acgcatagcc
    49981 tgaaatagtt ttgccgtctg ttggttgttt ttcattttct ttctctactt tgggagaatc
    50041 ggctgttagc tcagcttctt ctgtcagccg tttttccttt tcttcttcat tattcaactg
    50101 gtgtaactcc ttcctgttct tttaattgat atttctccaa cgtatctaaa tacgtaaagt
    50161 tcaaacttgc tagtaaacga tcgccaccat ccatgggggg tagccccatt ttcgaccgcc
    50221 cctcattaat cgtgagaagt gaccctttga cctgatccaa tacatttttt acttttgttt
    50281 caggatcagt ctctagtaac tgatcggaat taaagcggat attggtttca agtttcgtat
    50341 ctaattcact cacaaacaca ttaaagtaat gaatcagcgt actttggata tactggagat
    50401 tactttgaac ggtgctagaa tgttcatttt caacgcctaa acgctcaatc ggtacaccaa
    50461 acgccttggc aatttgtttt gtgttccaat cattggaatt gataagcttc aaaacatcgg
    50521 tgtttatttc taatgttttg tagtccattg tttcatcaag aatgatcgtt ctaagagcat
    50581 tatctccact acttgaaccg ttggcttctt caaacttttc acgaattgcg ttctttgctg
    50641 atccgtctaa atctgactta tgaaccttca aaatacctga cccactgaca ccacgagtaa
    50701 agaaattgtg caatgtgcgg ttgccagctt gttgaatttt cagttcatca cgtaacgcat
    50761 aaagtggtgg taatcctgtt aaaccatctt gggtgaaata tttgaagtgc aaaatatcgc
    50821 tagacttcac acgtcttttt ttatcaccaa tctgataaga caacgtacca ttatctaatt
    50881 gagtaaccgt tacacttgag ttaggtaata agtgaatttc ttctaccttt tcaccgttgc
    50941 gtttaatctc tgcaaagcta ttaccgttta gcaacatatt gaccgccaaa gcaaacttta
    51001 aatgccaacc atccatttct gaattaggtt tctcgtttag taacttcacc agttcattat
    51061 cagcttgtgg catattgttt ttgaccaatt gaatcggact tgaagcaata tcactagcaa
    51121 taattcgaac ggctgcaaac acatcactat ttcttaatgc acgaacgctt gtaaagctgg
    51181 tggtgtaatc atccgattgg attgatacca catgttgtag gaaaggatct cccgttgtat
    51241 tttgtctcgc tttaaaaaat gccatctttt aacctccctt ctgttctgta tttagcatga
    51301 ccgctacccc aataagcact atgcccagcg ctaacaagcc atagtagaca tttgttagta
    51361 aggtgatagc aaccaacaca cacaccaatc caagaagtaa aagaacggta tgaatgtaat
    51421 tagaaagaaa attcttcact tgtataaaat tcattgtctg ctttcgctcc ttccgttgtg
    51481 gtgaagtaat ccattgcaaa cacataggca ttgattaatg cagctattgg atcaattttg
    51541 ttactgttct ttgatttatt aatctgaatg ccgttgttat ccgtttttaa aatagcgttg
    51601 ttcactgcat gggtgagaat cgtattttta ttgtgaataa cgttgccttc ataaacttgt
    51661 tctctaaaag ttcgggtcgg aacgtttaga gtaatcgttc cttgtcttac ttctaacatt
    51721 gggtagttgg ctttttcagc tttactgata agcgaattag cgttatacgg gtcataacaa
    51781 atccccatac attccaaatc attttcttga atcaaatctt gaataaactg aaatacttgg
    51841 tcatagtcca cgattccact ttctaattga gtaatggaac actcaccagc tttttctagt
    51901 tctcgataag gcaaaccgtc gcgcttttct ttgtcttgaa gcccatattt ggtggctaca
    51961 aagctatgtg aatcacaata aagttcgccg ttatctagcg gtacgatcca tgaaacgcta
    52021 gttaaatcat ctgttttaga taaatccact ccgatataaa cgggcttgcc tgtaatatct
    52081 tgtggttcta cttcggttgc ctgccagtct tcagcaatca tatagctgtc ctcactcgct
    52141 tgtctccata aattgaagtt tttcaccaat acagaattaa ggttattttg tttcaaagca
    52201 aggttcacat catcttgaat ggttggaatc attacttttt tgatttcttc actttcaaaa
    52261 atcggattgg ctttgatcca tttctcttga tcgtgaattt cttcgggatc gtccaattcc
    52321 catatcgcta taaagtacct gtcggcttgt tcttcgcctt ttagcacacg atctaacaat
    52381 aagtattcct cgtacatagg aacgtttaaa tcaagcccag cggtactaat aacacacaat
    52441 aagccgttct tttgttgggt cattcctgac ttaatgacgt tgtacgtttt acgagttttt
    52501 gcttcgtgcc actcgtcaag aattgcggtt gttggtgcaa acccatctag cgtgctggtt
    52561 tcactagcca gtgccatagc gaacgaatta gagggcaagt gctgaatctt agagttcata
    52621 attttcagtt gtggtcttaa aaacttacta gacttgacca cgtttctaag tgaattagac
    52681 agcatatcat agcccaattt agcttgtttc aaagcgttac ttacaaacaa tacttgcctt
    52741 gcttctgctg gttcttgttc cataatcaac gcattggcag ccatgccact tgcgatatac
    52801 gttttcccat tcttacggct catactggta aacgctcgat tgaatcgcct gtaattccct
    52861 tctttagtac gccagccata aagactgcct agaatgaatt tttgaaatcc taacatcttg
    52921 attgctttac cgtccgtaga tggtagcaac tcaatgaatt taatcgcttt ggtggcttgt
    52981 tcttcatcga acacataagg gaagctatct gacttagaac gctccaaatc gcttatatga
    53041 cgctcacacg cttggataat tttcttgggt gcaatcagct tacctgatag gactttctca
    53101 atgtaatcat tcatgaattc atcaactctt tgaacgggtc ttcgggttca tcatttttaa
    53161 ccttgttcaa agctagtttt gatcgtgatt ctaaggtcat acctagtgag gtggcttgtt
    53221 ttttcaaatc actcatagct tgtgattgaa cccgaaccgc tggattggct ttctttactc
    53281 cgttttcgca tgtgataaac gtacctgatt ttcttatctc ggcttcggct gttttcattc
    53341 gagcaaaggc taaacaatag gctaccaatg aaccataatc tgcttcactc aatggataat
    53401 ctttttttaa tgttggtacg atacgattcc attcacttct agcgctcgct gccatccagt
    53461 cagggggcgt gatatttatt aatggttgct gcttgaacaa ttcttctcta gcgtccacac
    53521 ggattgcttt ttcttcactt gatatattgc cttttgtatc gtgtaatatt ttagggtgtc
    53581 ccatgttgtc ctcctttcag acaaaagaaa aaggaacgta agcaattaag ctcacattcc
    53641 ttcgtttttc gatcagaatt tttctttatc taatttatct atataaatga tttttccgtt
    53701 ctgcatttga atggtcactt gaccaaaatg aggtaactca atggtgcgct gtttccctgt
    53761 tttatcagta ataacaattg tatttttcaa taaatctcct actttcatta tatacttttt
    53821 cacttgtgat tacaagtgta atcgttattt gtaattaccc ttatgccttt tcacaacggt
    53881 tatttgtacc aaaatgagta ggcatcgatt gtcagtaagt ttcacactat gcccccttaa
    53941 ctcaaagggt actcttttct cgtctttgtc tttcattggc tgtcttggaa ttatggtgtg
    54001 catggcataa agaacgaaaa ttagtttcat ctaaccgtct attccaatca tcttttagtt
    54061 caattttgtg atctacaaca tcagctttcc ttatcaagcc ttcttctagg caatcctcac
    54121 atactggatg atttaaccga tacaagtatg aagcctttcg ccatgttcta ctttgataga
    54181 attgaaaata tttaccttcg ctttgctttc tttcttcacg cttaattgcc gtttgctttg
    54241 ctttatgctt cccacaatac ttctgcctat aatcaatcaa tgttttacat ccagcatgat
    54301 tacattgttt tttaactgcc atagattacc aaccaaagcg atctcgttcg tcagaatcat
    54361 cttgttccca ttttgatttg tattcaatat aaggcgaaac tatcttcaag cacgttccgt
    54421 ctttaaaatt aactttagtg attttatctt cctcaaaact aataaagtct acatcttctt
    54481 gagtgtttga atactcaatg tgtttctcac catcgaagta tctaatactt tccatatgca
    54541 taattattct acctccaata aattagttat caattcatca tctgttagta gcaaagccaa
    54601 gaacttatca tggatgttta aaaacaaatt atcctcattc gatgtaagct ctcgttgtct
    54661 cgctcgatca tataggttaa gcagacaatt aaattcatcc attagctcac ctgtatcatc
    54721 atagttgcca ctatctacca atgatcccac tactagcgat tgacaccacg ctactgactc
    54781 ctgcagccaa tcaggttctt cttccattat ctttaatact tctggatcaa atgtggaata
    54841 atcttctgtt accaatccca cactaaatgc cagcgtgttc attagaaacc gatccatttc
    54901 atctgtatat tgaaagttcg gtgctttgtt tgttgaaata atattgagca tttactttcc
    54961 tccttgattc gtaacacgtg gtaacaccta cgtaacaggt acccgttacc actcaatccc
    55021 aacggggaca agggttctag cgttttggta acaggtaacg ggtaaaatcc agtaacatta
    55081 ttccccagca tattagctaa ctatttcaaa agttttaagg aaataaggtg ttaccccgtt
    55141 accaaattgc tgtatccctt ggggcagtaa gggtaaacta gtaacgggct aggtgttact
    55201 gacccgttac tacccgttac tttttgtact ttccagctcg atttttattt tcataggcat
    55261 ttgacttatt gtaaaatcct cgtcgtttat ttctttttgg cagttgcttc cgttcccaac
    55321 caggaatact gctaataatc aaggcaatct ttttagtttc tgcatctgat cgaccattca
    55381 ataaatcctt tgcttgttta tcaaaaacag cttccaaaat atcagcggtg agtacgctat
    55441 caactaaata aaactcttgt tgcatagtag ctccattata gaaatgctgt aaatttttct
    55501 cattacattt actgtcagga tagttctgat aataagaacg tctcgcccac gctggagctt
    55561 cttcccattt atacgggatt tccatttcca aatatttagt gattgcttct ttaattggat
    55621 tctccatctt ggcatcctct tgatagtctt ttgcaatttc taagacttct ttatcttcat
    55681 cgggactaaa atagattcgt tgtcctttat caaaaagcac ctttgcttca gctaacactt
    55741 gaagaaaata ttcatccttt gttttaaacg gattcatctt tggcttattc ttacaaggca
    55801 aaggataaaa acggcggttt cctgtatcat ctttcaaata ctgcccatca ttcgacgttc
    55861 caataaatac acattgcctt gcccaagcta tgacattccg accataagga ggtctaattt
    55921 tatcgatctt ggcactgatg aagtttttta tctgttcaat tttagttttg ttcattgaag
    55981 ataattctcc aagttcaata attacattgc cttgaagctg catataatca tctttctttt
    56041 cacctagcga atctaatgaa tcggtgaaaa aatcatccgt gtaaagtaat gctggaacgg
    56101 tactcttacc aatcccttgc ggtccatcca aaactggaac gatctcaaac tttattcctg
    56161 gtttatagat acgtgcgact gatccgacta tccaacgttt tgttacttct cgtgtgtaaa
    56221 ggttgtcgtc tacccctaaa aggtcaataa acagtgtttc cagtctaggc tgttgatccc
    56281 atttaacttt ttcgatacgt tcttttactg ggttgaaaac attctttcta gccacattta
    56341 ctactgcttt gtgtattttg ttgtcatcaa aaactacatt gtagttttct tcaatatatg
    56401 ccgttaaggc atcctcaaaa ctgtcttccc attctccagc ggtacgattg atccaaggag
    56461 aatcttttaa taggtgaatg tatccgctaa attcgttata agcaattgtt ccagctaaat
    56521 tgctatcatt ggttaaaatc aattctgcat tcacaacact gttactttta atctgatcgt
    56581 ctttattgca tcttaatcgt gacatccagg ttttcaattc aatgatattg tcttcacgct
    56641 cgctggcttc gggaaagtct aaaatactat ctaatttatg cttatgagcc atgagctttc
    56701 cccctcaaat cttttttaat catcgatcga ataatttgat tcacttcttt atcttttagc
    56761 ggtggttcat tgtacgcatt tgctgtataa atcaattctg ctaaagtttg attatctaca
    56821 ccgtgccata gtaaccaacc gcataactta gttaaatgat cgtttctact accttcgcca
    56881 gcgccttgaa caatcatatc taattttttt gctgtccctg tttttgctac gggtcggtat
    56941 tgagtcttta tttcttgcgg tttttttagc agtaggttca ctagccaatc gggagctggt
    57001 gcaatattat ttagagatac gttttcaata ggttcatatg ctctcccaac acttcttgaa
    57061 ataatcatag ttggcgctat tggaactcct ttagtgataa tatcaatccc gcttaaactt
    57121 ttacctttat catcacgccc gaagatatca gcaaatgcac ctgtttcttg ttggataatt
    57181 acaccatcag gaattttaaa gaagaaatgg attcctttac ctggtgtgat ttccgtataa
    57241 gtagaaggaa atggatcata cattgaagca agttttttat aattctcaac gccgtttcgt
    57301 gtttcagaat gttgatctag gtcaactacc accatttgat gatcttcaag cattaaccca
    57361 atatttctag ttgcatcttc cgtccaccat tcattaattt gattagaatc gttagttgca
    57421 tcattccaac cactagagcc ttttattgga attttagttc caggagataa gggataaatt
    57481 gaccatcccg acttttgtaa ttccgttgct gcttgataat tatttgccaa taaacctctc
    57541 ctcctttttc aaaatactgg tataaatcat tcagacacct ccatgagctt caactgctca
    57601 agttcgtatt tcaacccatc ccgaacaaat tcagcacctt ttaattgatt ctgatacttt
    57661 acccatgtat taaatgtttt cacccttgct tcttgcatat cagtaatgtt taaccatgcg
    57721 gttaaaatct gattttttag ctcgttgatt tctcgacaaa ttattttgtg ttctgcatgt
    57781 tttttgagta catacaaaac tgttagtttt tcattgaatg aatttccaaa gtaggttttc
    57841 ccgatattat tttctagttc agcgatccct tgattaattt cctctaattc aaggctatcg
    57901 agttggttta atagttttgt tttgtacatc tacttatgcc ctccagttct taattgatag
    57961 tcgtactcgt cataagcagt gaagagatat aacgctaatc ctgcaaagat agctattttt
    58021 gcaattaatg gtaataagcc gaaaattccg ccgattaaaa tgcttcctat aattaagttt
    58081 cgtttcataa tggttccctc cgatttttta atatggtata atcggaacaa agaatatcgg
    58141 gttttatccc aattaagttg cctttatcct gtccgccaag actgttatgg ataaggcttt
    58201 ttctttgttc tcgatcatgt taatgctcct aagttgtctg caattcagca gaacgattat
    58261 aaattttctc actcactgaa aactgcaacc catatttttc tttaacagtc attaattcta
    58321 ctgtctcatc taaaataggt tcacgatcaa ccaacatttc aggagtcata tctttctttt
    58381 ttaccatttt ggaatgacca taaatagttg atacagcttt attggctatc acattcgctt
    58441 taatgtagtc tactggtttt ggttcagtaa tagcgtggct taatttagtc attgcttctt
    58501 tttggtgttc tttgtctagc atgcggaata cttgaaagcc ttcaagtcct gtggactggc
    58561 gtagttcttt gatgatgtcg aaaatccagt cttgaaatgc ctcggcttct tttttacggc
    58621 ttttgaatgc catgcggtaa atattttttt tcgttgatga tgtttacatc ttgtgttctg
    58681 cccaatgaat cgatgacctt actagtagta accccatctt taggcaaaga gtgaatggct
    58741 ctagtaacct gtttaagacc taacgcttcc gcaacatctt tcgccactgc ccaccattca
    58801 tcattaatat cgacaaatct tataatgtgt ccgttccaaa tttcagtttt cattcaacgt
    58861 cctccagttc aagccctagc aagctcgcta acaactcaac ttgctgatac aaaatttctt
    58921 gatactcttc aatagaaagt cgttctttaa actctgcttg tactaaatcg ttcaagccac
    58981 gcaatactcc gcttaccgtt ggttcttgtg gtagcaattt ttgatagtcc atttgttcgt
    59041 acaaacattc aaacgtttct tctagcgctt tgccttccaa gtttgctaat tctgccgctg
    59101 tgtcttctgt aagaattgtt gataatactt tttcgattgc tttattttgt gtcgattcca
    59161 ttattatttc ctcctattaa tccctttgcc cccacggctt gcgtttattt ttggtattct
    59221 tccataaagc gatcacattc atcttgtgaa attcttacga ctccatcaac tataatcaac
    59281 tttaaaccgt taggaacata tttctgcatc atagtattgt atgaaacgtt catatactta
    59341 gcagcttgtg ccttgttcat atattttgga aactggtact ttttttctaa taatgaaagt
    59401 aacgttcctt gagtttgctc tacttgttga acaactcgat cgtcaataat tttaaaagct
    59461 ggatcatcaa gcgtgagttt gtcaattttt aattccatat ttatcccccc tcgttagcat
    59521 acatttctat acaaagattt taaaaaaatg caagaggctc ttgaatacat ttctatacct
    59581 cttataaact caatatacca tcataccttt tcatttgcaa gaattttaac atactttttt
    59641 gaacttttat gtttcacaca tatttaaatc gtgatatagt agagaaaata tatgaatggt
    59701 ggtgaaaatg tggctagaaa aaaatacccc gaagcagtgg agacaggaca aagaattaga
    59761 ctggctagaa ttgaaaaggg actctcaatg gaacaacttg gaggtaaatt atccccaccg
    59821 gccagtaaag gtgccgttag taattgggaa aatggctata atcttcccaa taacaccagg
    59881 cttaaacaac tttcaaaggt attagatgta tccactacct atctattaaa cggatcttat
    59941 acattaagag atatgcatat gatgcccgaa attaagcgaa atgtgcttga aaagcaattg
    60001 aaaaaaacta ttgaaaaaaa taactctata attgattcta atctttctaa tgctatcaat
    60061 aacatcgaag aagataacct gactgtctca cagaagattt atttaacaaa cgcaataaaa
    60121 tatcttaaaa caggatctcg aattgaattt cctgacggga gtaccccaat tgcttatctc
    60181 gcagctcttc taaatacgct tttacgatat gactcattaa ttaatgattc agaaaaaaat
    60241 acagatgaga aaaaagagta tcaagaattt tatgaaaatg atcttctaaa agagttcaca
    60301 gctcttgtta ctgagctaaa taaacactat tcaaaataat aataaactgc ctcctccaac
    60361 cgcccccacg gcttgctaca ctatggaggg aaaactatta tggcaacatt caagcaatat
    60421 gaaactaaaa aaggtaaatt ttggctctat gaagcctatc ttggaatgaa caaaatgact
    60481 ggcaaacctg ataaggttcg tagacgaggt tacaaaacaa aaaaagaagc ccagcttgcc
    60541 ttgtcacgct tgcaagtgga ctacgataaa aacggtatta aaaaagcgaa caacgaaacg
    60601 tttaaagaag tttatgactt gtggctagaa acatataaaa ccactgtccg agaagccacc
    60661 ttcatgaaaa ctgaaatcaa gtttagaaag tggattcttc caaaatatgg aaatcttcgt
    60721 gtgaatgaag tcacggtaaa aaaagcccaa caaattgtaa atagctgggc tgaaactact
    60781 gaccaataca aggtacttca ttcaacttct aagcgtattt ttagctacgc tatcaatctt
    60841 gggattattg agactaatcc actagacaac gtattaatgc ctaaaagaac caccactaag
    60901 cataaagaaa aggtcaaagt ttacagtaaa gaacaactga tcaccttgtt tgattaccta
    60961 aacagcaaac ctgaaactta tcgaaacgac tttgataaaa cgttactacg ctttctcttt
    61021 tatagcgggg ttaggatcag tgaagccctt gcattgaatt ggtcagacat tgattttcaa
    61081 gaaaatacgg tcaccatcaa taaaacacta agccaatcca aaaatggcta taaaatcagt
    61141 gatcctaaaa ctgattgtag tgctggggtt cttccactag atgaaagaac aatttctata
    61201 ttaaaaaaat ggcagattaa tcagcggaaa tatatgctga cacttggtgt aactgatccg
    61261 actatgattt tttgtggtat ctataaagaa ctaatcacac accacgctat ttatgcaaga
    61321 ttgattacta tttgtgaaaa agctatggtt ccatttctcg gtgtgcatgt agcaagacac
    61381 actcatgctt caatgctctt ggacgctgga gctactatgg tagaagttca aactagatta
    61441 cggcatacaa aaattagtca gacgatcgat tgttacggtc acttggcaaa agaaacgaaa
    61501 gaaaagactg ttgaaaaatt agtacaacac ttaaatattg actagatggc atacaatatg
    61561 gcatacagta aaaaataaaa aaaggagaaa ccctatcata tcaaggtttc tcctagcttt
    61621 atagtctatt cttcttcttc cgccatgaag ttaagctcat taaagataat tgacgatagt
    61681 tggtatttca acgatttttg aatagaacta atcactttat taagtctaat tcaccttaag
    61741 tggtttttta gtcgtattca aaaacgtatt caagttgcgt ggcgtgcttt tgataagaaa
    61801 tcgtaagaac tagttaatca aacgacttat aaataatgta acaccactga ttaatcagct
    61861 atatccaaaa aaacaagcat tcattcagat acatcaatct ctatagaata caaagctttc
    61921 attatctcaa accattacca caacttggca agtcggttaa ttgaagaaca cctcattctc
    61981 cacttatagc agtggagcaa caagttgagc tattgttgca acagaagcta agaattctgt
    62041 actccattta agttttttta gactatctac cgcaaacctc agcatagttt ttttaggctt
    62101 ttctttaata gcttcatctt taatggtttc gatatactcc tgagcctctt ctacctcttc
    62161 ttcaggtaag gaatcattca aattctccaa aagcaaatca agctttgata ataattccga
    62221 catatcatca atagaaacaa tcatattatt attgtggcct tgctgtatat tagtgttgta
    62281 actatttcca aatatattta ctttattata tattgaattg ttgctcatat agtcctccag
    62341 tcgtcctgct gcattacttg catcttgtaa cgtcacaaaa aaatctctcc catgttggta
    62401 aattgattca acgatttcaa attctggatt tccatattcg cgccattcgt attcttcctt
    62461 aaagtatttt ccgtaactat ggttaaattg cacagaattt ttaccaattt tccttagaag
    62521 ttttatctct ctctcagaaa taaaattttc ctcaaaagct gattcaacta tctgaaaatc
    62581 actaagaaat gttcctaaac agaagattga ttcattaata gtttgttgaa aattccatgg
    62641 tattttgttc caaaaaccat tcttaattaa agcctctttt ttttcaacaa tctgtgattt
    62701 tacattttct gtatatatct tccaattatt gacgtcttcc ttaatgtccg aaatcgattg
    62761 accttcataa gaagtccctc caccaaaaag tccttgaacc attttatctc atcctctcta
    62821 taataattac tctaaatcca atacttgcta caaatgatag catttcgtgt ggtaacatga
    62881 ttgccatcgt tcctgtttta tttactctga cttcaatact tggtttgttg atgaaatttt
    62941 accaattgat tccatcgatc gtttcatgga atctgtattt actattttca ttgattgtag
    63001 agattgattt attccctctg ttgcacttct gataccttta gtatcaaagt tttgcatgat
    63061 tgctcgctga gctgataaag ctgataatgt ttgacctatt gactctatcg acctcttcat
    63121 ggaatctgta tttaatattt ttattgattg tagagattga tttattccct ctgttgccct
    63181 tctgatacct tcagtatcaa agttctgcat aatttcttgc tggactgata atgtttgacc
    63241 tattgactcc atcgactttt tcatggaatc tgtatttaat actttcattg ctgatagaga
    63301 ctctgacaat ttagtaacac ctgctaaatc gatattacta aaataatttc caatatatcc
    63361 ttcaaaatca tctgacatat cactaaggtc ctcaccagca atatctccag ccaatatttt
    63421 ttgaaaagct ttctctagtt gatttgtata tctcttcaat ttctttatta atttttggta
    63481 taaagccatt tctatttctt tgttatggct tacaatattc ctaccttctc tgattaaact
    63541 catgtctgtt tgaatttctt ctagcttaac atccatatat ttactaaata cttcactcca
    63601 caaagaatat gaatcagata tagtgtgact gttatcttga aataacttca ataattgatc
    63661 ctgagatatt tctttatacc ttacaatatt ctcttcattt tcttgtgtaa ctaaaatata
    63721 attttctcca aagagatatt cttcaaaatc atataaatct atccattgta aaagattctt
    63781 tgagtcaaac tttcctattg cttgtatttg ttttcttttt attgacgaaa tgatttcatt
    63841 tggaattgat tcctctgccc agttatcaga aaaatatgcc ggagctaata aatagattaa
    63901 ttttcttaat gcccattcgt aactatgcaa atacggtaat agttttttcg aaaaaaacaa
    63961 cgcatttgta tctaaaaggg tagtgtagtt taattttgat ttacttgctt caatattgac
    64021 cttagctagg aaaatttgaa atatatgtac ctcttttatt cctatcttac cagtcttatt
    64081 atattgaaat actacgtgta acgaatcatt atagttcttt atgtcaaagc caaatttata
    64141 atttttttcc tgctcctgaa atcttaagat agaatcacta atatatggtg acaacacttt
    64201 cagaaaggtt tcttcgatat tttccattct tcctttttta ggataatata aatattcaac
    64261 aacttgctta ctaatatgtc atcaacttct ttcctttcaa caattttaat tttcctatta
    64321 acttgatatt tgctacataa gccacaacta gcaaacagaa agagaacttt ttctttacct
    64381 tgataactgt gttaattact ggtttctttt ttctatttct ttatagtatt gttcttctac
    64441 ttttaatatt tttttaactt ctctttttat gtcagcatac atagatatac tgttgtcctt
    64501 tcggttgaag cagtgataat tctcaccatc aaactcataa aaaagcatat cacttgagct
    64561 tccatctgaa ttaattaact gaaatttggt attgagtagt aattcatttt tctcgtcatt
    64621 caactttatt aaaataggtt tgatctcttt taaataattg aaatatattt cggttattac
    64681 taaattaaat ttcgctactg tataaacata agagatacgt ggggaatctc taaattggtt
    64741 atatatatct ttccttaaaa catctaactc cttttttaat tgtccgttaa aatcaaaatg
    64801 aggcattgct agaatttcat ccaaatcaaa gtacactctt tgttgatgaa tatttactgg
    64861 cagatgacca tgctgagaat aatttctcat atgtaataaa aacctatacg aaaaatgctc
    64921 atcataaggc ttactcagaa ttttattctt aaaagattta aaatcttttt ctgctaaaaa
    64981 gtttttcata caaacttcaa tggattcagt caaagttttg gctgaactaa ttaagtttat
    65041 cgtcaaagca tttatctgat aataatactg gtcttccgtt aatttttcac ctgtactttc
    65101 aattaaatca ttagtaaaaa ttgtgaagtg tttgagcaaa ttagttaaat tatatctaaa
    65161 cacattaaaa agtttatcca actctataat atgacgtgtt aattctacat aatttaaaaa
    65221 tattctttta tcagattctg ttattgtttc taataatgaa tcaatctgcc ttattagctc
    65281 gtcatcttgt aaattactga caaaaaacct actatcactt ctcataatta tattctccta
    65341 atatgatttt ttcaaaataa tcaatatgta acatagaagt atactctatt gttacatacc
    65401 ttatttctta ttatatcagt atttctctgt gacacataag ggtgtaacat aattatttta
    65461 aacgaaatga ctacaagtag tcattgaagc aaatctccat aagacatttg taaaatcttt
    65521 taaaaagaag cgtcgaaaga aggaactttt cttcaacgct tcttttattg actcaatttt
    65581 caatattact tgaacgaata atctgatttc taaactctcg aaaaacttct tgtggttgat
    65641 aatagtctgg atctatttca aatgtttctg agaataattc attgaatttt tctactgaaa
    65701 taatgatttt accattcttc tctcgactgt tttctattat ttctgcttct aattcaaata
    65761 aatctagtga cgaactaaaa tcataaatcc tgtcatattg aataaaaaaa tcaagaaaaa
    65821 gttgctcaaa ctcttcctta tttatcacta atgtttcaaa cggaacaact ttattttctt
    65881 cagccattct tccaatttcc tcactttcat tttcaaaaat cacaaaaatg atattaactt
    65941 aaaagccact aacaaaataa gacttacaaa gtaaagggta atccaacaaa ataaccattc
    66001 gctctacgta ctacgatttg gtagtcctgc ctttcaatcg gtaattcata atagtaattt
    66061 actgtttctt ctttgtcact ttcaatatac tctggattat ctaatatcat agcatactca
    66121 taaagctctt caccatcctt attttcaatc gaccattgtt gtggacgtat tggtttttct
    66181 gtatcatttt taagtgtata ggtcacttgt aatacacgat catgttgtgc aaattcattt
    66241 cttttttcgg tcacttcaat atttttaaat gttagttcaa ccccatctgc ctgataagtt
    66301 tcacctattt ttaaatctat tgttacaatt tttattggct tttcttctgg aaaatgtctg
    66361 gctttaattg ttagataact tccaaaaaga atcaatccta gtagcactaa aagaattcct
    66421 ttaacgagcc actgaaacgg gaagtaaact ttaaacatct tttttctcct ccgttttgta
    66481 tttgtttttt agagaatacg ataacttttg atcaatgtca tcaagctttt caattacttc
    66541 attacttatc attgattcta gttctgaaat tttttgttca aatttaatgc tttcagaatc
    66601 attaaattta ttatttgatg gactagctaa cactggtaaa tttgaaacca taacacgaaa
    66661 catatttgcc ttggaaccaa aaactccttt gttttggttg taaaaattgt tgaatatttc
    66721 tttagtttct tctgaagccg agactttaaa atatggatag ttcatttttt tcttccacct
    66781 ttcttttttt gggagggagt ctgtagggag cttgctccct cagagattta cccaccatct
    66841 gacttgccag aaagtagcct agcgtgagcg gggcggattg actggcaagt agatgggtag
    66901 ctggcgtatg tcctaaaaac tgcttctttc caagcaactc ttcataggca aaaaactgga
    66961 aagtccacta acaagcccat tcagaattcc atttcaaaat tttgttgcct tttttgctga
    67021 ttttcaatca tttgttgtgt gaattcataa tcctttttag cacgatacat ttttacatcg
    67081 tcattcatta tgcgactgat ttgatagtga atctgtttag cagaaggtgt atgagaacaa
    67141 ttttcaaaac cctttgccgg tagaaataac tctttctgat cagtcttttt aatagaaatt
    67201 gttttacttt tcgcactacg taaagtttga ggattcacat ccgtatgaag tttaatcgtg
    67261 tattcttgat catcttctaa agacattgtg tttacaaaat gcttgtctac ctctcgcaag
    67321 aagtcatcat atttaatgaa tttttcatcg ccttcacggt cgctaaattg cttttgtgcg
    67381 atggaatcta attccacaaa aggtacattt aactcaccag ttttgtaatt tactccacta
    67441 attagcgaca taacttgctc tctttccata ttaaaaaaat tttttatatg tgattcttct
    67501 aaattctttt caagttgttc agaaacagat tcaaatgaat atcttttccc taactttctt
    67561 gcactaaaag tacgttcgac atactgactt ttttcttttc tagattgttt atctcttcct
    67621 aaagtaatta actcacctct acgctcatag aaatttacac cttgtttgta aagaacatag
    67681 ccaagtttgt tatttgtttt tgaaaattga taaacttcaa tgttatattc ttttgccaaa
    67741 tgatccgaaa aatcttcaaa agaattcact tcgcattttt ccaacgttgc ttcgatcgca
    67801 ttttgcacaa actcttgata attaattttt ccatatttca tcttagaagg atcgtttgaa
    67861 taaagattgg ttctcttttc taagttttca tagtactcat tattcactga ttcaagacca
    67921 tgttcattga ggacttgatc gttaattttt cgcattagtt ctaaatcttt agggtcaata
    67981 cgcaaccttt tacatgtttc catgttaata ttattaatga caagatgact atgaaaatga
    68041 tctttatcat tgtgacttgc aacaatgatt tgcgaatttg gaaaagcttt ctctgcaaat
    68101 tcgacagcta tttcgtgcat tttatcaata cttaactctt tagaagtact cttatcaaac
    68161 gaatgaataa catgaaacgc ttgtgctata tctttagatt tattcatctt ggtacgtact
    68221 aaattcattt cttgcagtgc ttcctcacta tcatcactac aatttattcc tgagactgca
    68281 acacattttt ctttttttga aggattagct gcatattgta atagcgagga taaatttttc
    68341 ttgcgtcctt tcgatgttat agtagctccc aaagttgttt cacctcatct tttaaacttg
    68401 caataatctg aattgagtga attaaattcc gatcaacttt ttgggaatac tcttctttcg
    68461 tacccggtct agtttgcttt tctatccaat attcgaaata ttctttttct acttctgata
    68521 atttaaaaaa agagggggca ctccgattgg actccaaaaa aatgtcatct ggataactaa
    68581 tcatcaactt ttttgctatg ctattcgcaa gttcatcttt aaaaatgttg taacggctag
    68641 catcaaaact aaaatgtagg ctcttttctt ttttatcttc agattcttct ctaaaatatt
    68701 tagcaatgat atttaatgcc tttaccgctt gattcaaatt gttaccaatt tgatttaact
    68761 gtttggttaa aactacccta tcatcttcag ctaacaacgg cggttcatat ttgagtccct
    68821 ttaaccgctc acggcaaacg tctgctctag aaattcccct ttgttttgca atcaatgtca
    68881 gttcaagata agtcttttta tcgacacgaa aatttaaggc ctcactatgt ttgcgatttt
    68941 tttcgtacat tttttgttta tcatccattg attatcccct cacatttttt tctagagagc
    69001 aacatttgaa atcgctctct atttcatttt tcatctttaa ttcttcttga atcatcagtt
    69061 caatataatt agtgaccgtg attttttcat ttgttgcttt ctttactgat tcacataatt
    69121 cgtcaagttc taagaaatca tgtgtactaa tctgtagaat taattgcatg acaatcacct
    69181 ctttattttt taagtaaact atcgaaaagt ggattaggat cattaagtgt atctctgaat
    69241 aactcgttgt cttcataggt aaaccttcgt cttggttttg atcccttatc attttcacgg
    69301 atttcactat caataatcac tgtttcatga tttgaatcaa attttttcgc tgactttctg
    69361 tcttcaacga tattgatttt ttgtgttttt tctttcattt ctccactatc tttttgaacg
    69421 ttctcccgaa catctactgt tttgaatcct tgactacttg tagaactttg tacattttct
    69481 cgaacatcta ctgtttttgg ttgacttgca ctgctacctt gcacattctc tcggacatcc
    69541 actgatttaa acccttgact acttgtagaa ttttgtacat tttctcgaac atctactgtt
    69601 tttggttgac ttgtactgct actttgcaga ttttctcgaa catcaattgt cttagtacct
    69661 tgagcatttg aagaactttg taaattctct cttacatcaa cattccgtcc aacatgacca
    69721 ttcagtgaac cttgaatatt ttctcggaca tctactgatc ggccaccatg actacttgta
    69781 gaattttgtg gattttcttt gactaatttt tctaatcctg tatttgaatt tttagcttct
    69841 tgaattcttt ctttggtcaa cgcttctttt ccgtcaatat tagcgcctgt ccgcccttct
    69901 acacgtttcc ttaacattat ttcctcgcga ttcattgctt caggcgtgta tttcgcttca
    69961 tgacgcttct gattaattaa ttcttcagca gacttagctt gaccgtgcat agcattttta
    70021 cgttcttcaa tatcttgttg gactttttgc tgaattgcac ttacaggatt attattcgat
    70081 tcagcattat ttttcattgc ttcacgcata cgttcagaac tagacataat actatcggca
    70141 ttttcaacct tagcaccatc ttttctatcc gaaagacgtg ttggcatgga atcagcatat
    70201 tttccagttt catcttcttt atttttagct aacataggtt tgctattttt attaatagcg
    70261 gacacagtac catcatctaa accttcttta aacttactct tggtatcatt agctatatca
    70321 cgcatactct taaatggttt tgttgctctt tcactagcca ttgtagatcc atctgaagct
    70381 aaacctgata atccacgttc atgagcatac ccaagcgctt tccccgtttt attagctttt
    70441 ttagaaagtg attgtccaaa gttgcgttca ggttttcgtt cttccccttc agcttgatcg
    70501 tttccaccat tatttttccc acctttagac cggttcatac cacctgttcc tttacggaat
    70561 agcattgcac ccattccaaa agcagaagca agttgcccat agccttcttt gagtccaata
    70621 tccacaccaa agtatctcat gactgttcca ctgcctttga ttaaaacaaa cacagcacag
    70681 atataagcaa ttgtttttat aaaaatattt gctgagatac cttcgccagt atttaggtaa
    70741 tttatgaaca ttgcaaacat agataaaccg aacccttgaa atccgactgt caaatagcac
    70801 tgtaaaatat ctgacaaaac ttgttttgat cgttgtcctg tttctaagtc agtagcaaat
    70861 actaaaactc cgagtacacg tttaaatgct aactcgagta ttgctgtaat tataatgaaa
    70921 gcactaaaaa catacgctac cgctaaagca atcaatccaa aagaaattcc ccacaggttc
    70981 gcttgatagc gataatatcc tgatttgata ccatcaacaa aggttgataa aaaattatct
    71041 gaaaatttag tagcaacaaa ttcattatca gaattttcaa ctaattcata acgcagatta
    71101 tcagctgttg ggttctcttt ttccatttta tcaattacat tatctgtcaa tacttgcgta
    71161 agatccgttt tccagaaatt ttcttttgtt agattatttc ggtcatttgt tttatcaatt
    71221 gtcgaatatt gatctgtctt attaatataa gctaaatctg tcactccctg ctcaatcaat
    71281 gaccatgcta caccgccatc ttgattattg atactagttg cgtcattata aagagtcttt
    71341 gcaaacatta ttcctgaaag tttttctgtt gatccaatca aagtcggcat taaaagaatt
    71401 aatgctacag acatcactac gttcattcca accgatttta aatccactgt tccttttcca
    71461 gtaatcattt tgtaaccaac aaacatcagt gaaagtatca ttaaaccaat aacaactgta
    71521 cttaagaccg attgataaac tttattcatt cccgtacttt caataaagct aaacaaatct
    71581 aacacttcgg gaatcatatt ttgaatacca tctacaattg caaacatcga ttttataaca
    71641 gaccacccta tccacaatcc aaactgactg taaaaatttc cgttatattt ttttaaatac
    71701 gattgataga caggattatt caaaaattca gtttgacttt ccgtgtcatc aaaccaattg
    71761 aaaatgcttg cttggacaac attaccggtg aaaacaacga taaacattaa aacaagtatg
    71821 ctcaaagcta accagtgtat ttttctactg gcaatctttt ctttaactat tttcattatt
    71881 acctccctca gcccattttc tgagactctc agagagcttc tgagctgttt ttctgtcaat
    71941 tatgatatga gttacacaat tgtcattttc agatcttaaa tcgagaacta tagtgttgaa
    72001 gcaaatagtc tcgattaatt cgagattatc tgtattttga tctagacacc aaacttgatc
    72061 tattaaacga ttttcaatca aaataacccc tcctatattc aaagttctca aatgaagcgg
    72121 agatacccct ccacttcatt tgactcaatt ctattcttat tgcttatcta ttccttcact
    72181 gatttgcaat tcaattagtt ctaacgcttt attttttaga gaagcaaaga tataatcgtc
    72241 tttttgtttg atacggtgat ctgtttttgc tcttcgtatc aagtcacgta aagtcattga
    72301 tagctgttct ctaacataat ctacaaaata cttgttatta cagatttcat agataatttt
    72361 cagttgaatt ttttgttctt tttcagcaga tttaatcgca tatttgaatt ttttatacca
    72421 gtcataaaat tgactgtaat cgttattacc cactaatttc agacagttta caatattatc
    72481 cccccatacc tgataaagcc attctttttc aattaatgat tcaattaata tttcatctaa
    72541 ttttttattt tcaactgaaa gtgaatcaat aaagtcagca ttttgagatt ctttaaaatc
    72601 tttaaaatct ttagaagaat gattaagttc ttgtaaaaat ttttcacctg gaagcgggaa
    72661 tgacttatca ccatcgaatg ttgatttgtc ggaaggtgta tttttttcac ttggactgta
    72721 atgttgattt gtcggaaggt gtaaattttc ctcaatgcac ttttttttgt agaaatctcc
    72781 ttcgctgaat tctggtttca ataaataata aaaatttgga ttattcttcc cagttttttt
    72841 gttaaatcca ttttttttaa tcgtaattaa tttatattct tctagctctc tcaaagcgct
    72901 tattaccgtt ttctttgtta aacaagattt ttcagctatt ttttctatag caaaaatcaa
    72961 aaaaattctt cctttgctgt caacttttga attctctaaa gaatattcat tttgtttttt
    73021 caaatacata taaacttttt ttgtactttg tttcatcttc ttatattttt tatgtttatc
    73081 taaaaaaatc ggatacttca agtatttttc agcatatacg tcatcttttg agtatgcata
    73141 ctgagcaatt aatttatcta tttcttccat ttattcctct tctttctaat aaatgttaaa
    73201 atgtagtcaa ataaagtttt cttagaactt tattgtcgag tgtttcctgt ggtcgccaaa
    73261 ctgtcgggaa cactcctttt aatttttttc aaagtatttt tatattttct atacttcatc
    73321 attattcaaa caaacacttc cttttttcta tcaaaagcac gccacgcaac tttttatact
    73381 tcatattctt tgataaacct tgctaattct tcttttctaa taaattgaca atctccgatt
    73441 atgcttactt ttaaaccttt ctctctgata aattttttta atgtacttct gctacagctt
    73501 aaatacttac aagcttcccc caatctaaaa acttctttgc ttagagatgt ttcaattcga
    73561 acttgatcta ctgcttcttt tgcaactcga tagaaatatc ttcgcaattc ttgatctaaa
    73621 tccgatggaa gaataacttg aatctcagat ttcattttct ttgcccccac taatttgact
    73681 acatgtattc aaattcaact tttcgtcact tttcattaaa aaaaatttga tcaattgtga
    73741 tattttcaat tcctttttct ttcacaagat acttcaaaat aatcatttct tctggagaat
    73801 agtttgtttt accgctttct ttgtttctta ccgcttgtac tgaaatgcca tatttttcag
    73861 caagttcaga ttgtgataat ccacaaaact ttctaaaatc tttaggcttc atgactcctc
    73921 actcctcctt cttttcaact tttcgtcact aaaagaataa catatattta ttcataccgc
    73981 aacgtaaaat tcaactttta tctacttttt catttcatta tatgagaatg tagtgtaaac
    74041 tgtagaatag aatagatgaa ggtggtgaaa ccattttgtt tgataaaaac attaattctg
    74101 aaattggaaa acgaatacaa gaaatacgtg tttctttagg gtatactctt gaagaatttg
    74161 gcgaaaatct gacacctccc gcaagcaaaa gcaatgtttc tagatgggaa aaaggaaaga
    74221 acatacccaa caaagcgcgg ctactaagta ttgctaaact tggtggtgtt tctactgaat
    74281 atctactgac aggtaattct caaaaaacta agaaatatat caagtattta ttcaatgaga
    74341 ttttttttga caacggtacc ttccataaca aattcaaaga tttcggtaaa gacagagata
    74401 ggcttggtct atatgactta tttttagcag tatcgaaaac atatagtcta gataaatcac
    74461 cttctttaaa agataacttt gtagaaatga ttatagatga tgtatataaa aaactcttgc
    74521 aaactgataa atcagatgac caactcatcc tgggtttcat atatatttgt cttgatgaaa
    74581 aactttcaaa cagacagaaa agtcttaaaa gtatcaatta tgaggtattc aattatttag
    74641 gtgttgcatt tggtttaatt gatagcgaaa tcaaatctac aaacgcaggt aacgatgaag
    74701 atttattaaa ttatttaaaa gaattaacat cttttattga tgaaataaaa acaactacat
    74761 tcaacaaaaa aaaatatttt caaaatcaat atgatataga agaataaaga ttacattttc
    74821 ctatcaaaag cacgccacgc aactgatagg aggaaaaaca atggcaacaa ttaaacaata
    74881 tgaaaagaaa gacggaacca aagcttggat gtttcaaaca taccttggaa tcagcccgct
    74941 aactggtaaa gaagtccgta ctacacgtag aaattttaaa acaaaaaaag aagctcaaat
    75001 agagcttaat agactacttg tagactttga agagaatgga cttaaaaggg aaacgaacga
    75061 aactttccaa gaagtgtatg atctctggta tgaaagctat aaaactactg taaaagaagt
    75121 cactcaatta aaaattgaga tcaagtttaa taaatggatt cttccaaaat atgggcagtt
    75181 tagaattaaa gaaattacta caaaacatgt tcagaagata ttgaatcagt gggctaaaac
    75241 aacagatcaa tataaagtcc tacattctac cgtaagccgt attttcaaat acgcaatgac
    75301 tctagggctg atcactaaaa atccctgtga gctcgtaatc atgcccaaca gaaatgttga
    75361 aaaaaagaag gatactgtca aaatttattc acgagatcaa ttagaaacct tatttcaata
    75421 tttggaatcc aaaagaagta cgtatagggc agagtacgat aaaactttac tgcgctttct
    75481 attttttagt ggctgtcgaa tcagtgaggc tttagcctta gactggtcag atattgactt
    75541 tgattcaaac accgtcacta taaacaaaac cttaagccaa acaaaatatg ggtacaaaat
    75601 ttcaagtcca aaaacgagaa atagctatgg ttccctatct ttagacaata aaaccattaa
    75661 ttggctaaag aaatggcaaa tcaatcaaaa aagatatatg ttaaccctcg ggattactga
    75721 tccaacaatg attttttgtg gaatctacaa agaaatcatt actaaacacg ctatctattc
    75781 tcgtatgatc acaatctgca agaattctgg tattccattt ctaggtaacc atgtaaccag
    75841 acacactcat gctagtatgc tgttagagtc gggagtctcc atgaaggaag ttcaagaacg
    75901 ccttagacac tcatcaatca aattaacaat ggatacctat gctcatctaa ctaaagaaac
    75961 caaagaaaaa accgttgaaa agcttgcaga gcacctaaat ttctagcgga acgtattcaa
    76021 tcccgtattc aattcaaaac aaaaaaaagc tgaaccctta tctaccaagg gttcagctat
    76081 catttacagc ttattcttct tcttccgcca tgaatgtatt gaatacttct tcaatcatgt
    76141 cccattctgc gtctgtttcg atttgttcta actcgccttc tgttccatct tcgttttcga
    76201 tgtatgcata agcttgtaat tctacatctt catcttctga aacaccagca ggatataaaa
    76261 gaacatagtt acgtccaaat tcttcttgtc cgtcaactgt tagtaggatt tcatataatg
    76321 tttcatttcc ttggtcatcc accaatgtga tgtgttcgtg tccttcatgg tcgtgggaat
    76381 ggttatgttc tgtcataaga ttacctcttt tcttttatta ttaaaataat tgcttacctg
    76441 agccgtctaa ataattttgt aagatcatca cagctgctaa tttatcgatg actttttttc
    76501 gtttggctct tgaagtattt gcctgctcta ctagcatacg ttctgcctga acagtggtta
    76561 atcgttcatc ttgataatca actggcaagg agaatagttc tttgatcttt tctccgtatg
    76621 acatggaagc ttctgccctt ggtccgatgg aattgttcat atttttaggt aatccaacta
    76681 caaaccggtc tacttcatat tgtgctacta attccttcaa ccgatcaaag ccaaactctt
    76741 cttctgcttc attgatccga atgatctcta ctccttgagc tgtccagcca aaggggtcac
    76801 tgatagcaac acctactgtc ttagaaccga catccaagcc cattactctc ataaattcac
    76861 tccatgattt gagaggtagt ccttgacaat tacttccatg atctcatcgc gttcgtgacg
    76921 gcgaatcaaa tttcgagcat cacgataacg aggaatgtag gccgggtctc cagaaagcaa
    76981 gtagccgaca atctgattga ttggattgta gcctttttct tccaaagccc gataaacaat
    77041 cgctaatgtt tcgctcactt cttttttgcg actatcgtca aaaccaaaac gtacggtttc
    77101 atctgtaaaa cccatgattc tacacctctt tcccgcaagg taattccagc ttaccttcta
    77161 caaccttatt ttactcgaag aaagggaaaa ctacaaacaa atattccaaa cttccgaata
    77221 aattaagaaa cactatttgt atgttttttt ccttttttct gtagctttat caaaagtact
    77281 cttttcataa agtatacgct atatttcttt gaatgtatgt ttttacacaa ttttttcata
    77341 atattcataa aaaattcgaa tagctgctac taattttttg tttttgttgc ttgtcctgtc
    77401 tcataattga tcgtgtagcc atcttgaaca ttgtagataa agacattgaa ttcaattttt
    77461 ttgtcttcaa tgctttctgc ttccaattgc actcccctgg ctaccagttc attcccctca
    77521 aaatgaggag tgacacggta gcgtacatga tgatttgttt ctttgatata tgccgcaata
    77581 tcattttcgt gagcaagcat gtatggagca ttcaacgaac gtgtccctgt catcaagttt
    77641 ttaatgttgt tattttgacc agtcagctgg aaaccaatta aatggctgcg attatataac
    77701 cattgcccgt cacttaattt cttttgtttc caacctgtcg ggtcaatata caaaggctct
    77761 ctcttttcag tagggaacaa atcttttcca agcatagcat tggcttgtcc tactctgttc
    77821 aatttatcaa tatttgaata gctttcccat gttcctttgg aaaggctaag atcctctttt
    77881 gtaaattccg gctgattccc attgatttct atttcttgat gttttccatc atattctggc
    77941 acatccgcta cttgagaagc ttgtggtgtg gaatcaaaaa tagttgtaat ctgctgaaag
    78001 atatctgaat ctttttgtgt ggtggaaaca ccgaatgccc ctgcaatcac agcagcgacg
    78061 atccccacga tcgccttggt tgtttttttg ctcatttctt tactccttta ctaacagctc
    78121 cctaaatctt aacatatgtt cccctataaa taaatactag aaagaaatag aaacagcaaa
    78181 aaataaaacc tgttttaaga tggcttaaaa atacaaaaaa gagacggatt cctcgtctct
    78241 aatcagtcac cactctatct gtaaggtatt tattattatt caaaaatttt cttcatactc
    78301 aagacaatac actgatttca caaccgcttg gtaaacggtg cgcaaaagct tgcatctgcg
    78361 gtaataagtc catccaagtt aaaaacataa gaagttgttt ttgcttggct gttcttatta
    78421 cttgttgcag agcagctttt tcacaaccta ttttaagcgg gtgacgggaa tcgaacccgc
    78481 gacatcagct tgggaagctg ggattttacc actaaactac acccgcaata caaaaacagt
    78541 atacgcctct tttattcctt cctcaagttt ttttattctt tacgcttctg gtatgttttg
    78601 tagtaaaata aaactaatca atcaattatt ggagaagatg ctatgacggg aaaagaatta
    78661 gatctgttgc tggacacttg tttactcgct gggaaaatca tgatggaaag caatgcggag
    78721 atgtatcggg tagaagatac gatgagtcga attgctttag cttctggaaa tttccgtttg
    78781 gtcagctatg tcactcaaac cggtctcttt attggtcttg atcgtacctc gaccatccga
    78841 atggaacaaa ttaccaaccg ttcgattaat ttagaaaaag tagtaaaagt aaatgatctt
    78901 tcacgtaaat atgttgcttc agagctaaca ttagaagaac tttactgcga actgcaagca
    78961 atcgaccgag accgttcttt ctttcctgtc tggttgcaaa tcgttagcgc ggcagtgatc
    79021 agtggaacaa ttatggtgtt atttggcgga aagatgaccg atttacctgt gactttagtc
    79081 attggaggat tgggatacgc agcttatcta tatagtttga aattttttag aatcaaattt
    79141 ttatcggaat ttttatcttc tttattgatt ggcatagccg ctatctacag cgtacgtttt
    79201 ggcttaggaa gcaatcagga tctaatcatt atcggatgtg tgatgccttt agttcctgga
    79261 gttcaaatta cgaacgctat ccgtgatttg ctagctggac attatgtctc aggagtttct
    79321 cgcggaacag aagcgatgat gactgctacg atgatcggtt ttgcgattgc ttttattttc
    79381 cagctttttt attaggaaag gaacacaagt atggggacga tatttattca gttttctttt
    79441 agttttttag cgactgcggc atttgccgtt attacaaatg tacctaggcg ttcattgatt
    79501 tgttgtggtc tttctggtgc ttttggctgg atgatctact ggatctgtgt tcaaataggc
    79561 ggatctgctg cttttggttc attgcttggt tctttaggag tagcattcat cagcgatctt
    79621 ttctctaaac gtttgaaaat gcccgtaacg attttcaata ttcccgggat ggttcctcta
    79681 gtccctggtg gtttagctta tcaagcggtt cgaaatctcg ttactgaatc ctatcgagaa
    79741 gcggctcatt atgcggtcca agcaattatg attgctggag caatcgcttt aggtcttgta
    79801 ttatcagaag tctttaacca taacatccgt aatttcaaag taaagcgtga cgcaatcatg
    79861 atgaaacgaa aaaaacggct ttttaaataa acgaagtgta acaaagaaaa ggttgtgaaa
    79921 gagacgttca gccttgagcg atgacaaaat atctcacaaa cattgcgaca agtaaccgca
    79981 ggagcaataa gaagtaatta tgagtattaa aaaaagtttt gtaaaaatag cttctcacat
    80041 ttttacataa aattgactta atactgagaa actgactttt gaacaccctc tatctgtaaa
    80101 aaaggggctg cgacatgatt tttgtcacgg cccctcttct ttattcaaat tttttccaaa
    80161 acgttcgttg ataataaacg atccatagag cggaaagtat tagaactaaa ccgatcacag
    80221 gaatattcac taaccaaaat ggataaaaca aagccaacat tccgtataag acgataagaa
    80281 taatactgat gatcaatgaa cccatcatag ttgcgactaa acccaaactt cctgaacctc
    80341 tgttaaataa ttggttaata ttggtccagt tcagcagcag caaccgataa tctctagcga
    80401 aataacgtag tgacaataag tagcagccga ataaagaacc aaatagcaag ctagggataa
    80461 aaaacaaagg cagctgaaaa gacagtccgc ttaataatgc gatcccacca gttaaaaaac
    80521 tctgcaatat ccatccgaat ctgaactttt cttttaaata ttggttcata gagattggca
    80581 aagaacggat aaacagaaaa ttttcttgat ccaaagaaat aagattgctg ataaaagaag
    80641 tctgattaac tgttaagaaa gccaatgcga tccctaccag gaaaacaaca ccgattaact
    80701 tattatctaa atcagttaat tttatttcgc ctcctagggc aaaagcaaga ataaaaatga
    80761 ttggagttaa caaggaagaa gaaagaactt gcataatcaa attaggttct tttactaatt
    80821 gagcattgta actaaataaa agctgatgca cattttggtt ctttttatgg gttcttttta
    80881 ttttgaactc actgtttgaa tcagtcagtt gctctgtaag ctttggtact atcagctgtt
    80941 ttacagcaag gaaaaatccc agagccgtga tagctagtat tccccaaccc aataaacctt
    81001 gttgagaaag tggctgactg gcagcatcat agaatggcaa taatatcgaa atcggatgcc
    81061 gatctgttaa ctcattttca atagtccccg tttgatgatt catccacatg attccagcaa
    81121 atgcgatcag catcgagctg ccaagcaaga tactagaaac tgtttttcta tgttttttaa
    81181 acactgctgt tcgagccaaa ccaaaaacaa tcaaactagc cagacaaaaa agaataatca
    81241 aaaatagaga aaacaaaagg attgagataa tgatagtaag caaaatccct agatcagctc
    81301 gccatccggt taaaataaac atgactagaa gcggaaaaac aaaaggaatg atggtcaaag
    81361 caactaccaa aatctttgct gaaaaaacct gttcttgtcc aaaaggcaga ggcaaaaata
    81421 cttgcaggtc atttccttca aaaaagatat tataaatgac tgatatactt tgagttaaac
    81481 ctaacatacc aaaaagtgcc acgtaataag taaagaaacc tggcaattta acaaagttca
    81541 tagcaaacat agcaaatccg taaatcagta aaaaaatcag ccctgaaaaa agattttgag
    81601 acaaaagata gatagttaat cgctttccct tttttccttt ctctcttgct ttattcgtga
    81661 gctgtggatt aacatataaa agattaactc gaattaattc taataattgt cgcttataca
    81721 tacggtccat ctcctgtcgc ttgccttcca gccattttca aataaatctt ttctagcgtt
    81781 tcatcaggtg agccattcaa taattcacta actgccccct gataaatcaa ttcacctttc
    81841 ttcaaaatag ccagtttatc gcataactgt tgtgcggtat ccaatacatg tgtagaaaaa
    81901 atgactgttt ttccttttgc ggcatgagcc ttcatcattt ctttcaaatc aaatgctgct
    81961 tgaggatcaa gtccttgcaa aggttcatcc aatacccaaa tatctggatc tggcagcaac
    82021 gtgccgatca aaatcgtttt ttgacgcatt ccatgtgaaa aacttgcgat tgtttcattt
    82081 tgatgactat acatatcaaa aagcgctgtc aattctgcta aacgcttttc ttttttttgt
    82141 gtgtctaatt cataggcagc tgaaatcaag tcccaatatt ctccagccgt caattgtaaa
    82201 aaaatatctg gggaatcagg cacataaccg attttttgtt tgatactcaa tcgattttcc
    82261 gtcaatttca ttccatctac taaaatcgtt cccgatgatg gttcaataat actaactaaa
    82321 cttttaatcg tagttgattt tccggcacca ttatgtccta aaaatccaaa aatttcccct
    82381 tgtcttatcg agagagacaa gtcttttaat gcttgttttt tcccgtaact tttacttaca
    82441 ttgatgaatt caatcatttc tgtactcctt ttgtttgtta ttacttttta ttgtaccctt
    82501 cgttattggt ggagtaaatg tcaaaaagag tgcataacaa aaaaggatag aaacgactag
    82561 gctgctactt gggttgttct cttctacagg aaaacactct tctaacaggt aagatatgag
    82621 tctttgtttt ctttaaaatg attcattttc tatcttttct tgcataaaat tctttagttt
    82681 atcaatactt ctctttccca tctctagttg ttctccattt gcaaatgtta ctatttcgtt
    82741 tactctgcta atagatgtaa tgttttcagt attaatgata taagctttta aatctttaca
    82801 taaatactca tattcgagtg attttttata ttttttaatt gtgccgttta cgagaatctc
    82861 ttcatctttc aatactaggc ctattttatt tttataacct ggcatgctca ttagataaag
    82921 gatttcatcg taatggatat agtgatcgct attaccataa cggacagttg tccacctttt
    82981 tttcgtagca tgttgaacag gatagttttc tttttctttc aataagtaac tttggatgct
    83041 ttttttattt ttttcataag tgaattcttt tatcaaataa ccactaggcg taatctttcg
    83101 attaataaca gttattgctt tattcggatg agacgttaga taaacaattt tacacttttc
    83161 attcttttct ctaagcattt cgcctagttc gataccgcta taataggcgt tcaaatcgat
    83221 gtctaggaaa aaatatctga ggaatagatt tcattatttt taatgaattc aacaaattgt
    83281 ataacgttca atccctgaac gatctcaaat ttccaaggac ttaataaaat tctggattct
    83341 tccaaaattt ctactagcat tttttcaaaa accaaactat catccaaaat aaatatacgc
    83401 gttaccataa aaagtacctc cactcgatat tttactatca aaatcatttc atacaacttt
    83461 tcaacataca tgttaggaat aaattgtaat tctcttcaca atcttttcca acacctttga
    83521 aaccgatatc aaatactttc aggatgctgc ttctaaaata aatatcaaac aaatgaatac
    83581 atcatgcaaa aaaagccaga caaccgacgt ccttgcgtgt cagctgtctg agctatgttt
    83641 atttattttg ttcttttaaa aagaacgata cacatactga tttttcggag cagagacttt
    83701 ctcagcgttt gtaacaacta cagatgggat ttcacgcttg aatggttgat aatagtctga
    83761 ttggatggtt ccttctattt tataccattc atcattttta accgttactc cttccggcat
    83821 atgcgtcaac aaaccaaaga ctcctgaatc tgccacacaa tggataatgc cgaatcggaa
    83881 caagaagata tctgtattgc tatcgttcgg tgtttggtaa acaaatcctt catagctgat
    83941 ttttttgcca atgaattcgc tagggtaatt ataaattagc tccataactt ctaaatagtt
    84001 ttcatctgtg atcttgatag tttgcttatc cccatacttt tctttcaact cattcatttg
    84061 gtctaagtag tctgatttgt tgaaataaat actggtatcc ggctttaagt attgtgtctg
    84121 catctccgga tcccctactg attctttact tactgggaaa ttaaatcctt tggcttctac
    84181 gatcgtagtg tcgagactaa ctgttggaaa caacgtcccc acgattactg gcaaagctag
    84241 cagtacataa gcgattccac gttgataagg ttttgacaac ccatggtcat gatcgtgctc
    84301 gtgtgccttt tcttctgctt ttccgttttt gacccacaaa tacagctgaa ctaaagccaa
    84361 aagagcagat aaaatcattg aaagaatagc taagtagcga taatggacat tgatatattg
    84421 atcgagtttg ccagaaactt gcaagtacat catcaattcg aaatacccag ataaaatcaa
    84481 aaaccgcagc atattttccc tcctaaataa ataatgtgaa tccaataacg ctaagggcaa
    84541 tcagtccgat cagcgataaa ataaagcgtc ctgtaaaata tcgtttcatc atcagtagat
    84601 ttttgatatc gaccattggg ccaaagacca aaaaggcagc tacaggtgct gtgccgaaca
    84661 gacttaacaa agaagatcct ataaacgcat ctgcttctga gcaaagagac atcgtaaagg
    84721 ccaataacag catgatgata atggctaaaa tctttgttga gccgagcgtt agcataattc
    84781 tagttggtaa ataagtctgc atcgcagctg cgattaatcc gccaatgatc aaataacgac
    84841 ctgtatcaaa aaattcgtcg attgaatgtg tcaacacatg cccagtttga tggatcagct
    84901 gattttttgg ttcattcttc tcactttgtt cttcttcatg gacatgatga tggtgatttt
    84961 ctgctacttt agacgtgatt ttttctttca atacagcgtc tttttgaaaa taggcaagcc
    85021 agacaccaat cacaagggca acaaaaaagc tgcctatcac ccgccagctt gccatctgcc
    85081 aagaattgcc aaatgcgata aaagtggaaa aaatcacgat tggattgatg atcggagcag
    85141 tcagcataaa agcaaacgct gtgtgaactg gtacgccttt tttaacaaat tgatgaacga
    85201 tcggtacgat gccgcattca catgaaggaa agaaaaatcc taagatcgaa ccagtaaaaa
    85261 tagagaagat acgattttca ggaagccatc tcttcacacg ttctggggtc aaaaatactt
    85321 gtaaggcgcc tgagataaga cagcctaata atacgaaagg taatgcttca ataacgatcg
    85381 ataagaaaat cgtactcatc tgcaaaaccg aatttggaat aaaagaaaac atgagtttcc
    85441 tcctttttat ttctagttca ttcgctttgc aaatatacgc ttttattcaa aaaaaacaag
    85501 ttgctctgta aatttttaca caactcttat tttttaccaa agcacttcaa ttgacttttt
    85561 ctgttattcc cattaaatta aggtctcata catatcactt ctatcataaa agggagaata
    85621 aaaatgaaac aaaccactaa cttgactgaa gttcaagaca tactgcaaca gtcatccgtt
    85681 gccgtcattt atctttcgat gcctaattgc agtgtttgtc acgctgttcg tccacgacta
    85741 gaggaacttc tcacacatta tgatattccg gcacttcatt tggatgcatt tgaaacacca
    85801 gaagtagcta gtaaatttga agtgctgact gcgccagttg tcctgatttt tcatcaagga
    85861 aaagaagtct ttcggcaagc acggttcatc gactttaaaa aaatccgtta tctactagat
    85921 gaactgacag cagaagatga ttccctttct tatgaagaaa tcttccgaac aaaataatcg
    85981 ttgtccaaac agaaaaaagc gattgaacaa gtgaaagttt tgccttcatt tgttcaatcg
    86041 ctttttattt ttattctgct gtattttcgg aatgcgcatt tgcgtcagaa tgcaagaaat
    86101 agatcaaggt ttgcaattca ttcgtcaaat caacattttg gatcaataca tctgacggag
    86161 cattcaatcg agcagcggta aagttcaaga ttcctttgat tcctgcttcc gttaactgat
    86221 tgactacttc ttgtgctctt tcagcgggta tcgttaaaat tgctacttcg atttgttgga
    86281 tcttgatttg ttctgacata tcttccattg gataaacggg gataccgtct acgatgcgcc
    86341 caacgatttc ctcattcaca tcaaaagcac aactgatacg tatgctatta ctttgatgga
    86401 atttgtattt tagtaaagca cttcccaagt tccctacacc gatcagcgca acatttgtca
    86461 attgatcgtc gtttaatgtc tttgcaaaaa agtgcataag atcttctaca tcataaccat
    86521 acccacgttt tcctaattcg ccaaaataag aaaaatctcg acggatcgtt gcactatcta
    86581 cttgaacggc ttcacttaat tcagttgaag acactttttt ctttccagca ttatttaaaa
    86641 tccttaaata gcgataatac aaaggcagtc ttttagctgt cgcctttgga ataatatgat
    86701 ctttcacgaa atgacctcca cgtattgtct aattacatct ttgatttctc catcatagca
    86761 gtatttatag gaaaaaatca attccattgc tcagatattg tgaaatttta ttctttattc
    86821 atttatttat catttctgca aatctcgcag tataatggaa tttatggtag actactaatt
    86881 gaaaaatagt tttttatttg aggagaattc acaaagtaga aaagaggatt ccatgatatt
    86941 attacaagcc aatcagattg ctcgccattt tggtgcagaa gtcttatttg aaaacataca
    87001 tttagaaatc agtacaggcg ctcgtgtcgc tttagttggc agaaatggcg ctggaaaatc
    87061 gactttatta aagatcattg ctggaattga agcacctgat gaaggaaaga tcgctaaaaa
    87121 taaaacagcg actctcggat acctcgctca ggacacagga cttgattcca atgaaacagt
    87181 ttggaacgag atgctgaaag cttttgaaca agttagacaa atggaagagc ggatgcgcga
    87241 gctagagatt ttcattagcg aaggtacgcc agacacacct gcttatagtt cttatttaaa
    87301 agaatacgac cggctgcaac acgatttttc agatcgaaac ggctatggtt atgaaaatga
    87361 aattcgttcc gtattgcatg ggtttaaatt cgattcttca ttttatgatc agaaaatcga
    87421 tactttatca ggcggacagc gcacacgttt agctttagct cgcatgcttt tgcaacaccc
    87481 tgacattttg attctagatg aaccaacgaa ccatttagat atcgagacac tttcctggct
    87541 tgagaattat ctgcaaagct atactggtgc attattgatt gtttcccatg accgttattt
    87601 tttagataaa gtagtcaatg aagtctatga attaagcaga agaaaaatgc gccattacaa
    87661 aggtaactat tcgaaatatc tagatttgaa agcagaacag ttagcaagtg aatggaaggc
    87721 ttatgaaaag cagcaaacag aaatccataa attagaagac ttcgttgctc ggaaccttgt
    87781 tcgcgcctct accacaaaac gagcgcaaag ccgcagaaag acattagaaa aaatggaccg
    87841 gctggatcgt cctcaagggg atgaaaaaca agcaaacttt ctattcagta tagaaaagcc
    87901 ttctggaaat gtagtcttgc aaatcgaaga tgccgctatc ggatatgata atgtcacctt
    87961 atctgaacca atcaatctag atatccgtcg tcaagaagcg attgctctag taggtccgaa
    88021 tggtatcggg aaatcgacgt tgctgaaatc aatcattcac cagatccctt ttatccgtgg
    88081 aaaagaaacg ctagggacaa atgtcaccat cggctattac gatcaaggtc aagctgatct
    88141 gcatacaaac aagacgatcc tagcagaatt gtgggatgag catcctacca ctccagaaaa
    88201 agagatccga agtgctttag gtgctttctt attttctggc gaagatgtag aaaaaccaat
    88261 ccctctgcta agtggcggtg aaaaagcacg ggttgcttta gccaagttag cgatgaacaa
    88321 agaaaatttt ttgattttgg atgaaccaac aaaccattta gatattgaca acaaagaagt
    88381 attagaaaat gcattgatcg attatgacgg cacactgctt tttgtttccc atgaccgata
    88441 tttcatcaat cggatcgcga caaaagtcgt cgaactctct gaaaatggca gcaaagtcta
    88501 tctaggagac tatgattatt atttagagaa aaagcaggaa gaagaagaaa tcgccgaatt
    88561 gttggcacaa gatgagccag aatctgctcc tgctcccacg aacaaatctg attattacca
    88621 aagcaaagaa cagcaaaagc ttatccgtag ccttcaacga aaaattactc aggttgaaga
    88681 agaaatggcg cggatcgatg aatggatcga tcagttggaa caagaaatgg tcgcgccaga
    88741 aaacctggaa gatcacgtaa aactcaatga gctgaaccaa gatttagaag ctgctagaca
    88801 agatcaagaa acaaaattga cggaatggga agaactaagc ttggaattag aagaatatga
    88861 aaattaacga aaaaaccaaa acagaaacca ttcatgctgt tttggttttt ctttttttat
    88921 tttatcaaac aaaaattcca tatttacctt tttcaccaat aagaagacca attactagtc
    88981 attctcacta aagcttctaa ataatagtaa tcaccccaaa tacaaggtgt atttacccca
    89041 ttatttttgg gcttattata aacagactgt gttaaaaagc catcttcttc ttccgttgta
    89101 gcatatcttt ctttcaattg tcgcataatt ttccaaacag cagactggta taagttcttt
    89161 tctgttttgt ctaatagacc tgattctatt aattctaata atccacaaac catgatcacc
    89221 atactagatg tatctttttc ttctctgcta gaatcatcaa agatcaaatc ccaataacaa
    89281 atggtatctt ctggcaaccg attcataaaa taattggcta atattttgct taaatcaaaa
    89341 tatttttgtt ctttcaaata acgataactt aatgcaaaac cgtaaatccc ccatgcttgg
    89401 cctctagccc aacaggaatt atcactataa ccttgatgcg tacttccata tcttggtttt
    89461 ccatctttga catccatata aaatgtatga taagttgaac catcttctct tactaaataa
    89521 tctgctgcat tttgaatatg agcctgagca gcttttttat atttttgatt tccagtttct
    89581 tcactcgccc aatacaataa tggaagattc atgcaacaat ccatgatcat tctaccttgt
    89641 tgtgaaggat cactaggatc tccccaagct tgtataactc ctgccttctc ccaaaaacgc
    89701 tgaagtaatg tttctgcagc atcaattgaa gcttccttca tttttcgatt tcccgttatt
    89761 ttataatctg ctacggttga taaagaatac aaaaaaccaa gatcgtgatg attagtgata
    89821 atttgacagt caatcctgtg gataaaatct atatctgctt tttcagctgt ttgttgaaat
    89881 aaaggatcac ccgtcttctc aaataacaac caattaattc ctgtccaaaa tccttctgtc
    89941 caaccaatat tgtctcttaa tggataacgt ccttttatag gacactcgct tgggaattga
    90001 tactgactgt tactgatacg tttgattaac ctctccgtgt gtctgcgaca acgctcgatc
    90061 tcattattcc attctttttc cattaattct ttataacatt catttatcca tttttctgga
    90121 tgtattatct cttcaaacat cactttatca agcatttccc caccagcctt tagcataatt
    90181 ttagtctttt tttattgttt ttattttgga tagttagccc ggttgtccca tcaaaatcaa
    90241 ttttgggacg attgttccat acttctaaac tataatcccg atcttgatga gcaaccactc
    90301 ctgttccgag ccaatgggtt ccttttccaa atgtaccctc taatccagga ataaaagtgt
    90361 tttcccatgt catcaagttt gtattgggca aacccataat agctgtggat tttcgtttaa
    90421 tagtatcgtc acttaaacag ataatacctg aaaagccagc ttcactcacc ctatagtttt
    90481 ccttgtcttc ttctatgatt attccttctt tctcaggaga acattcaata gcaaaccctg
    90541 tctcatatag aacatattct gtatctaatt ctactttgtg tacgcgaatc tgccagcctt
    90601 caaaaggaat aagccaagtt ctgatttttg cctgtaaagt aggttcccat gtagaggcaa
    90661 gtacctcttt cttacataca atgtctcgta cattatttcg aacgatgaac tgtccatagg
    90721 ttttgatgct ctcattctta aaactggtcg tgatatatgt gtccgctcgc tgaatcccta
    90781 gcattgaatc cattgccatt tctgctttca attgattcgc tcgcggtatc gaaaaaccaa
    90841 attgactaga ataagcaaat tttaaatatt tttcattggt caatgtatgg aaatttggcc
    90901 ctaattgtcc cgcattcaaa aaaaatgtat gtccattatc atgttgtatg agcaaattgg
    90961 cttctgaaag aagtttagtt ccttcacgaa taggcatagg catttcttta gccgtccaat
    91021 actcatggtc ttcaggtagc gccaacaata aaaaaatctt attcagccat aatggagata
    91081 acgtactatt atagggttca gtcaatgtca attgagggta ggtataacca atattcagga
    91141 tacctttttc atcaaatatt tctttttgca tccaccatct tatattccga ttgactaacc
    91201 ccttgatttc acctaattta aaaggcaaaa gatcggccca caacatagct gaccaaaagc
    91261 ttgaaactgc aaaacgataa atcatgcttc gaccaaaagg cacatttgca ccatcttccg
    91321 caaaaaaatg aatatagtct ctagaaaaat caatagctcg gttcttatat atctggctaa
    91381 tgggcttttc tggttctagt acgctataaa tcaaaccata ataatgaaat gcaaaaggat
    91441 tataataatc ttggcgacct cttgaactgt ctcgatacca gccattttga agataacaat
    91501 tttctatatt atcaaatgct tctttcagtg ctgattcttt aactggataa ccaaattttt
    91561 ggataattgt tccgacaatt atcttaaaaa attgccaatt accatctgca cattcatatt
    91621 caaaaatttg cgagaaccaa tgaataatct ggcttttttc tcctgtatct aattttttcc
    91681 ataataattg ttcatgatga tataacgcta ataacattgc gggcatttct accatacgct
    91741 ggtctctttc atgtatttct ccccaataat cgggatggga aggatctgtt ccagctttta
    91801 ttcctgatag aattaatttc aaccatcgtt catctaattg gtcaattgcg ggccccgctc
    91861 cccataaaac ccgagagaat ccttccattc ctgcaatttt atttccatat cctacccctt
    91921 gatgtatata atcaatttgt gcgccacttg ctcgataaaa cggctggagt ggttgattta
    91981 tctttttaaa taagtcaaag taatcctgtc tggtccttaa tagtggtact ggatgtttca
    92041 ttgtattttc tcctcttttt actaccaaat agctaattcc gactgttcta atcgaagtaa
    92101 gccttcaata aaaaaataat cagaatagat cagtggcaca ttataagtca gttctctatg
    92161 gtatgcttct gctccgcctc caatgatccc atcttcatcc atattccaat ttgcatagtg
    92221 cttttctgtc ttttggagta tattgatagc agcttcatga tacatttttg atcgtacaga
    92281 ggaaacatat cctgctaatt ccagaagacc gcatgcagcg catactccag cactggtatc
    92341 aatattcgaa tcttttacag caaaatcaat gagaggaata taaccagttt tttcgatttt
    92401 ctgaataaaa tttactgcta tcttttctgc tatagctaga tagtacggat tttttgtgta
    92461 acgataactt aacgcgaatc catataaagc ccatgcattt cctctgctcc aacaagaatt
    92521 ctcattgtat ccttgcccgc caagtaaccg aatatatttc cctgattctg catcaaattc
    92581 tgcgatatgc ccggttgatc catctttcct cactagatac ttagctgttg tatctgcatg
    92641 ctgccgagca attttagaga acctcggatc accagtttcc ctcgaagccc aatacagtaa
    92701 tggtaaattc atcatactat caataatcat ccaaccaggt ttatggtcat tccatgctac
    92761 taaatagttc cctgaaatat tatagcgtcc agcaagtacc gtagctgcat gtaaccctag
    92821 ttgtcgacta tgtttgtttt gagactgttg ataatgtgca atagccgatg gtaagaataa
    92881 aaaacctaca tcatgatgaa cgtctgaaaa atggtacagg gcagattcta ataattgttc
    92941 ttgttgtatt gctgcctctt tgaacttttc tcgttttgtc ttgtgaaaga gctgccataa
    93001 aataccactc caaaaaccat tggtccacca gtcgattcct ctgtccttta ttacgtctgt
    93061 atattttccg ttgtaagaaa tatatggaat tttattcccc attctgtcta attccgcatc
    93121 tatcttttca gaagctacat tcaaaatttt tcttgaccat tccttcgtct gttcattcat
    93181 ggatatcccg ccattctttt aatttttatg aatgtggagt tgctcctaga acgaactaga
    93241 tggttaacat tcgttatttt ttttacttat ttgcagctcc aatgtcattc tccttaaatt
    93301 tagactgcgc ccacacataa atcaagacca ttgggatcac tgaagttgct aaaattagca
    93361 taattgcgcc ataattaatt ggctcacctg tactagaaac cgtcatattt ttgataatta
    93421 agggaaccgt atatttatct ttatctgaaa gcatgactaa tggaaataga tattgattcc
    93481 aacttcccat aaagataagt aaaccactag taataatcgt aggtgataaa atcggtacag
    93541 cgattttcgt aaaaatcacc cactcattgg caccatcgat tctggcagcc tccatcagtg
    93601 ctgtaggaaa ttgactgcta tattgtcgca tcataaacac tgaagttgta ctggcaatcg
    93661 aagggatgat cacacctgca taagtattcg ataatcctaa acgactcata atgtaaaata
    93721 aaggaatcaa tgtggtaaaa aaaggcacca tcctagatag cataactgta ttgaacaaca
    93781 gtttattccc cataaaacga tactttgcta atgcataacc cgccattgta gaactggctg
    93841 tagctaaaac tgtactgatt acagcaataa caatcgaatt ccaaataatc aagggataat
    93901 tatatctcgc catgatggct tgccagtttt ttaatagcat atccccaaac ttgaaattga
    93961 ttccgccact taaaatttct tgattacttt gcgttgaagc tacaatcata tataaatatg
    94021 gcatcaaaaa tattaaggca ccaaacacaa taatgacgta cgtaaaaatt ctgctttgta
    94081 tcttttgttt agtcattttt atcacctccg aatttaaatt gaatagccga taatataaca
    94141 gatacaaaca ccatcgtcca ggcaatagca gaggcttttc caaaatcaac catttcaaaa
    94201 cttgttttat ataaattgac tcctacgacc aaagctgaat tttctggtcc attggaagtc
    94261 ccaaagaata tatttgggat attgaaatta cccaagccat tgatagtggc taaaactgtg
    94321 gccattaaaa tgattggctt tagcatgggg atcgttaata aaaagaattg ccgaaatttc
    94381 gatgctccat ctatttcagc actttcgtat atctctttag aaatcccttg aagaccagct
    94441 aaaaataaaa tagtgttata tcctacacta agccaaatca tcgtgatgat cattgatatt
    94501 cgtatccaaa aaggatttgt taaccactgt acaccgttaa ttcctagcgc attcaaaaat
    94561 ccattgaata acccagtcgg attgaaaaaa gtcatgaata cggaagctac agccaccgtt
    94621 gatgtaatgg ttggaatata atagacagtt ctaaaaaatc cttttccttt taactgtgct
    94681 gaattcaata aaacagcaaa gtaaatagct aatagcatcg ttattggaat tgatcctgcc
    94741 atgataatca aaacattcgt gtaagattta ataaacaatg gatctcggaa gatagctaga
    94801 taattgtcaa atccaacaaa ttcaaatgag tagccaattt tcataaaact aaaagcaaac
    94861 gagataatga tgggaatcaa aatcgtcaca ataaagaaaa taacaaaagg tgtgaccaat
    94921 ccataagcac tttttttatg agacgtatct gttgcttttt tcttgctgtt ctttattgtc
    94981 ttgcttggta acgaagattg tatcatcgtt aagtcctcct aatatttttt aatcaccagt
    95041 taattttacg ccgtacttat gagcaaaatt ttctgcttct tttagatatg aattttcaaa
    95101 atcacctgtt tgccaatagt tatatgcagc ggtagtcaaa taagacgtag catctgaata
    95161 agtggctggt aaaacagtat ttgatgtatt ttcattgatt ttattcaata gttcatagta
    95221 tttttgtcct ccttagtagt caaacttttt ctcagctgct tctgtttgat aggccaatga
    95281 gttagatgta gccacgccca gctccagtgc gttggctaag cattcttcat ctgtcagcat
    95341 aaatgtaaga aattgttgtg ccacttgtgg atttttggca tctttaggga cataaaaact
    95401 tgatcctcct gatactgcac cttttcctgg attttctttt gaaaaaggaa tcagtggagc
    95461 catgcgccat ttgtcagatg catcaggaaa attcaaagac atattcgtag cataccagcc
    95521 gccagcaaca aacattgcag attcttgaaa tgctttctca gcatcttgtg caccgtagaa
    95581 atgtacaata tctgagtcga tcatttcttt gattaacttt gcagcatgtt tcgcttcttt
    95641 agtattcaga cggatatttc cttcttcatc aagcaaagat tgattctgct gggctagcat
    95701 gttgataaac aattcttggt ccccagattc tggcaaggca attccaaaac taccagtttt
    95761 ttcttttaat gcttttgcca cctggatata ttcttcccaa gaactgattt cttcaaaatc
    95821 tacacctatt tcagcaaatt tttttggttg ataataacaa agtgctgggg taaaatcact
    95881 agcccaagga ataatcgttt cattactcgt ttgttgacgc aaaatattca atttttgatc
    95941 ataaaactga tcgccatatt tgtcataaaa tccatattca tcagcactat aaaaagcatc
    96001 ttgaaatttt tccagcacac ctgctgctga agtgtctgcc atggagataa tatccggcat
    96061 atcttcgtgt gttaccaatt ttggggtgat catttgtact gttgctgttc ccgaagctac
    96121 attcacaatt tttaagtcaa tatttgctcc agttttgcgg ttatagattt ttgcagcatt
    96181 ttcaacatag tttgtcagtt tgccgtttgc gacatatact tctaatgtag tggctttttt
    96241 tatcattgga tctgcgatgt ttgctgttac ttcttcgtta gtttttccac atgcacttaa
    96301 gctgaataat agggtaatgt ttagcaaagc tatcaccaat ttgtatcttt ttttcatgtc
    96361 tatcccttct ttcttttcaa gttcttatat aaaacgcttt cacttatgta tattaacgga
    96421 attagtaaca caaatattta tataaaaaaa tattttactt gtcgttttgg cttttcattt
    96481 ttgttataat agtcattaat tataaataga aagcttttta tataaaaaga gaaaggaaag
    96541 tggttctttt gttaacaaac aaccaatcct ccaatcttgt caaaaaaaca ctaacctatt
    96601 ccatagatac ccatcttcat ttatctgctg ctccctattt tcgactacta ataaatgaaa
    96661 gcgctaattt atatgctgaa tttgcacata aatctataga actagataat ccttcccttt
    96721 tattcattga taaacagcaa gaagtccaaa tcttttctac tcaaaaggaa acacaaactt
    96781 ttatcattat ccagttttat tttgatgagc aattattagc acatattacg ggacaatctt
    96841 tttctataga tcaagaaata acatctatca ttacttttct gaaaaatgaa cagttcaaaa
    96901 ttgattatct aaaacatagt aagccagcta tttcctatga tcaggaaatc aattcttttt
    96961 tcatactatg ccaacagatg agcattcatt tgctttcctt attagttact tattgtctgc
    97021 aaaaaattca attgtcttcc ttaccaaggc attatcaaca ggaacttgct ttattgacaa
    97081 taccttcaaa tgagaaagtc attcctaaaa aaaagcatat tctttattca gatgaattag
    97141 ttgatccaat catacgatat ttagaagaac atctttcaga aaattttttg cttgaacaat
    97201 tagcccaaat tttttttatc agtccagcca gcttaaaaaa acattttaga aaagtgaatg
    97261 gaaaaagtgt tattagctat tttaaagaac taaaaatgga aaaagcaaaa cgtctcgtgc
    97321 tagaaaatga attaacctat acagaaattg cagatatatt aggatttcat tcgatccatc
    97381 atttttcttc agcttttaaa aaatatacag ggttatcccc ttcaaagtat tatctatcct
    97441 taaaatagaa aaaaattttt aggttttatc cacaaattat ttctctatat tttctgtcta
    97501 ttcaaaataa acaataattt tccggcacaa ttatttgctg ttttttacca taacatagta
    97561 cgatcaacgt agaaaaggag atgtttttat gaaagttgtt gtcattggcg gtgtagctgg
    97621 cggtccttca tttgccactc gtttccgtcg attgaatgaa gcgcacgaaa tcattatcta
    97681 tgaacgcgga gaaaatattt cttatgcaag ttgtgctttg ccttattatt taggaggtgt
    97741 gatcactgac cgtgactcgc tgatcgaacg tacaccagaa atattgaaaa caaaaaacaa
    97801 catcgatgtc tttactaaac acgaagtaac agcaatcgat ccttctacta agcgattaac
    97861 agttaaagac ctatccacaa atgaagaaat aaaaacagat tacgataagt tgatcatctc
    97921 ttctggtgct agaccagatt atccggatat tcccggagtt tttgaagcag aaaacggctt
    97981 tgtcctccgt agtgtgacgg atgcggatcg aatcaaatcg ttccttgaag aaaaaaatcc
    98041 acaacatgtc gtcattcttg gtgcaggtgt tatgggtctg gaattagctg agaatttcaa
    98101 gcatcgcggc ttagacgtga ctttaatcga tcaattgcca caagtcgctt tcccttatga
    98161 tccagaaatt gctaatttag tttatgacaa attgctgaaa gaaggattag ccgttcattt
    98221 agaaacaaga gttactgaga tccgtgataa aggtcgagaa atagtattat cagatggctc
    98281 cgtcctttct gctgatatgc taatttttgc tgttggtgtt tctccgaaga atgaagtggt
    98341 gaaagcaacc ggcatacaat tatcagatac aggtcagatc attgttgatg accagttaca
    98401 aaccaatctg ccggacatct atgcgattgg cgatattatc gaaacgacta gtgtagtgac
    98461 tggtcagccg atccaaagta tgctttccag tgcggccaat cgtcaaggac atatgctggc
    98521 agatatttta aatggtacgc ctatgcgcta tcgcggatat attggtgcag gtgtcgcaaa
    98581 aatctttgat catacagcaa gttatgcggg aatgacagaa catgaattaa aagcatcagg
    98641 cataacaaat tataaaactg tttttatcac tccctttgac catgcctatt tctatccaga
    98701 agctacaaga ttaaatctaa agctgatttt tgatgcagat agcggtcgta ttttaggtgg
    98761 acaagcattt ggagaaaaag gtgtcgataa acggatggga gaactttctg tagcaatcac
    98821 cggaaacttg acagtctttg atttgcctga tttggagttg ccttactctc caccgtattc
    98881 tactacccgt gacccgttga atatagctgg ttatgtcgca atcaatcaaa tgacgaatat
    98941 cgtagaaacg atcaaagcaa gtgatatacc cgaaaacgat ttgaaagaag cgttcttttt
    99001 agatatacgt gaacctaata aagcaccttc tggcagtatc tcggcaacaa aaaatattcc
    99061 aatgaatgag ttacgagatc gaatcaatga aatcccaaaa gataaaaaag tttacattac
    99121 tttcagaaga ggattgaata cttatacttc tgcccgaatc ttggcaggtt tgggtatcaa
    99181 agcgattttg attgaagaat aaaaaaacga ccgcggtggg tagccgcggt ctaggagtta
    99241 tttttacttg aggagtaaaa atgaaaaagt atatagggtt gttggttggt atgtatatag
    99301 aatagaagat aaatgtgaag aaattgtgca ttatttcttc acatttatta ggttatagtt
    99361 taagaaagtt taaacattgc gcaatttaat tattttagct gtttcttttc ataaaaaaac
    99421 atgttgtgac tctgagacaa atcatagtcc atagtgatgt ctctagagta actacgccta
    99481 atattacgag gcatcatatt aatctatcag cactagtacc taaactagca tccctttcga
    99541 atattttttc ttatataata aagtttgctt tcactcctct aatctcacca aatcgactgg
    99601 cttgcgttgt gtgatactag gaactgattg gtttagaacg acttttctat tgtaatcata
    99661 tttttcgcca tcctcgttgt cttctaatcc ttcaatgaat gatccctaat gtgtgtatta
    99721 aataatttaa tttttttgtt cctatttatt taaca
//
LOCUS       DBGZHO010000004        90125 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.004, whole genome shotgun sequence.
ACCESSION   DBGZHO010000004 DBGZHO010000000
VERSION     DBGZHO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 90125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.004"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="ACN3HL_000408"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="ACN3HL_000408"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HHC8005316.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="ACN3HL_000409"
     CDS             1011..2258
                     /locus_tag="ACN3HL_000409"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HHC8005317.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="ACN3HL_000410"
     CDS             2334..2678
                     /locus_tag="ACN3HL_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005318.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="ACN3HL_000411"
     CDS             complement(2795..3121)
                     /locus_tag="ACN3HL_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005319.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4695)
                     /locus_tag="ACN3HL_000412"
                     /pseudo
     CDS             complement(3494..4695)
                     /locus_tag="ACN3HL_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            4812..5327
                     /locus_tag="ACN3HL_000413"
     CDS             4812..5327
                     /locus_tag="ACN3HL_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHC8005320.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5526..5972)
                     /locus_tag="ACN3HL_000414"
     CDS             complement(5526..5972)
                     /locus_tag="ACN3HL_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HHC8005321.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6019..7497)
                     /gene="msr(C)"
                     /locus_tag="ACN3HL_000415"
     CDS             complement(6019..7497)
                     /gene="msr(C)"
                     /locus_tag="ACN3HL_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HHC8005322.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7851..8480)
                     /locus_tag="ACN3HL_000416"
     CDS             complement(7851..8480)
                     /locus_tag="ACN3HL_000416"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHC8005323.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8464..8928)
                     /locus_tag="ACN3HL_000417"
     CDS             complement(8464..8928)
                     /locus_tag="ACN3HL_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHC8005324.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9415..10683)
                     /locus_tag="ACN3HL_000418"
     CDS             complement(9415..10683)
                     /locus_tag="ACN3HL_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HHC8005325.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10914..11651)
                     /locus_tag="ACN3HL_000419"
     CDS             complement(10914..11651)
                     /locus_tag="ACN3HL_000419"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8005326.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11718..12287)
                     /locus_tag="ACN3HL_000420"
     CDS             complement(11718..12287)
                     /locus_tag="ACN3HL_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HHC8005327.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12415..13287
                     /locus_tag="ACN3HL_000421"
     CDS             12415..13287
                     /locus_tag="ACN3HL_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8005328.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13629..14501
                     /locus_tag="ACN3HL_000422"
     CDS             13629..14501
                     /locus_tag="ACN3HL_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHC8005329.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14498..16456
                     /gene="nagE"
                     /locus_tag="ACN3HL_000423"
     CDS             14498..16456
                     /gene="nagE"
                     /locus_tag="ACN3HL_000423"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HHC8005330.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16707..17558)
                     /locus_tag="ACN3HL_000424"
     CDS             complement(16707..17558)
                     /locus_tag="ACN3HL_000424"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8005331.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17681..18148
                     /locus_tag="ACN3HL_000425"
     CDS             17681..18148
                     /locus_tag="ACN3HL_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HHC8005332.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18411..18893)
                     /locus_tag="ACN3HL_000426"
     CDS             complement(18411..18893)
                     /locus_tag="ACN3HL_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHC8005333.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18993..19856)
                     /locus_tag="ACN3HL_000427"
     CDS             complement(18993..19856)
                     /locus_tag="ACN3HL_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHC8005334.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20454..21302
                     /locus_tag="ACN3HL_000428"
     CDS             20454..21302
                     /locus_tag="ACN3HL_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HHC8005335.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(21473..21814)
                     /locus_tag="ACN3HL_000429"
     CDS             complement(21473..21814)
                     /locus_tag="ACN3HL_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HHC8005336.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            21900..22607
                     /locus_tag="ACN3HL_000430"
     CDS             21900..22607
                     /locus_tag="ACN3HL_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HHC8005337.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            22594..22917
                     /locus_tag="ACN3HL_000431"
     CDS             22594..22917
                     /locus_tag="ACN3HL_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HHC8005338.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(23006..24043)
                     /locus_tag="ACN3HL_000432"
     CDS             complement(23006..24043)
                     /locus_tag="ACN3HL_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HHC8005339.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(24490..25473)
                     /locus_tag="ACN3HL_000433"
     CDS             complement(24490..25473)
                     /locus_tag="ACN3HL_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HHC8005340.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(25889..26659)
                     /locus_tag="ACN3HL_000434"
     CDS             complement(25889..26659)
                     /locus_tag="ACN3HL_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005341.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(26652..27587)
                     /locus_tag="ACN3HL_000435"
     CDS             complement(26652..27587)
                     /locus_tag="ACN3HL_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005342.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(28181..29830)
                     /locus_tag="ACN3HL_000436"
     CDS             complement(28181..29830)
                     /locus_tag="ACN3HL_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HHC8005343.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(30025..30921)
                     /locus_tag="ACN3HL_000437"
     CDS             complement(30025..30921)
                     /locus_tag="ACN3HL_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHC8005344.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(30914..31594)
                     /locus_tag="ACN3HL_000438"
     CDS             complement(30914..31594)
                     /locus_tag="ACN3HL_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8005345.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(31595..32377)
                     /locus_tag="ACN3HL_000439"
     CDS             complement(31595..32377)
                     /locus_tag="ACN3HL_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHC8005346.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(32370..33287)
                     /locus_tag="ACN3HL_000440"
     CDS             complement(32370..33287)
                     /locus_tag="ACN3HL_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHC8005347.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(33290..33574)
                     /locus_tag="ACN3HL_000441"
     CDS             complement(33290..33574)
                     /locus_tag="ACN3HL_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005348.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(34402..35523)
                     /locus_tag="ACN3HL_000442"
     CDS             complement(34402..35523)
                     /locus_tag="ACN3HL_000442"
                     /inference="COORDINATES: protein motif:HMM:NF019371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HHC8005349.1"
                     /translation="MAKLKLQLEEEERVNQVSEELSEEIKDLCKKAKNKEIFSITDQI
                     KYARFKGIEISESDESIVQDILLYRTYYFKVTAYRKNFEKDINGKYIDLSFVKLADLA
                     KIDMYLRMILSRMIFELEHSLKTLIISSITNSLTEDGYKIVEDYDMYMQNKFIDSQRK
                     KGNTKTNEEILSEYTQASEKILDKVKGKFGYDFDFYNHHHDKISIWALLEVMTLGNLE
                     RFITFYFEEEHFGYLGLKTAQKLLKYVTNVRNASAHSRPLIYNIVEPYQFGRADSNLK
                     KRRPVIQLTQFATNAGLDSELIARALTNMKMNDIVATIYLHEKYVQTQKLKTTNFEAL
                     SDLLDRIKVNGKMYEKNHELVEVFHFFEKIVMEYGKLIT"
     gene            complement(35573..37189)
                     /locus_tag="ACN3HL_000443"
     CDS             complement(35573..37189)
                     /locus_tag="ACN3HL_000443"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HHC8005350.1"
                     /translation="MSNASEITAKLWAMANKLRGTMDASEYKNYILPFMFYRYLSENQ
                     DEYLEKNGLDEYYEVTDSEEKEDYLEEISRGIGYAIAPEYTWEQLVSKIENHQIKASD
                     FQDMLDSFNLNAKRNPVAEDDFANVFSDINLGDTRLGSNTNERAKALNDVVLMVNDFT
                     FKDDSGHDILGDVYEYLIGQFAANAGKKGGEFYTPHEVSQVLAKIVTKDAKADDTQFR
                     VYDPAMGSGSLLLTVKNELPDGNKQGSVDFYGQELNTTTYNLARMNLMMHGINYRNMN
                     LKRGDTLDADWPFAEKDGMQIPLKFDAVVANPPYSAKWDIKNVDREKDTRFKGYGVAP
                     ASKADYAFVLHGLYHLDKTGTMAIVLPHGVLFRGASEGRIRKNIIDNNLLDTVIGLPA
                     NLFYGTSIPTAVLVFKGRESRRTKDILFIDASSEFVKGKNQNKLSPENIDKIIETYEK
                     REDVEKYAHVATLDEIKENDYNLNIPRYVDTFEEEEVTPLPHLAQELADVKQEIEKST
                     DKLFEMLGELHGTTDEAQEELRKFMEMLGR"
     gene            complement(37205..38419)
                     /locus_tag="ACN3HL_000444"
     CDS             complement(37205..38419)
                     /locus_tag="ACN3HL_000444"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHC8005351.1"
                     /translation="MSNEITKEPEIRFDGYEGDWEERKVGEVFSERSERSGEGELISV
                     TINSGVVKASELDRKDNSSDDKSNYKKVEVGDIAYNSMRMWQGASGYSPYNGILSPAY
                     TVIIPKKDIDSKFFAYDFKRYDMIQTFKRNSQGLTSDTWNLKFPTLKSVKVMVPSIEE
                     QKQISTFFESLDTTITLHQRELDLLEQTKQTYLKKMFPKTGEDKPEIRFAGFTDAWEQ
                     RKLGEVATRVTRKNKKLESTLPLTISAQFGLVDQNTFFNKQIASKDVSGYYLLKKGEF
                     AYNKSYSNGYPWGAVKRLDKYDMGVLSTLYICFRPVDINSDFLASYYDTDRWYKEVSK
                     HAAEGARNHGLLNIAASDFFETELMIPKNNNEQEKIADFFKSLDTTITLHQRELDSLK
                     EMKKTLLQKMFV"
     gene            complement(38416..39417)
                     /gene="rhuM"
                     /locus_tag="ACN3HL_000445"
     CDS             complement(38416..39417)
                     /gene="rhuM"
                     /locus_tag="ACN3HL_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010621011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RhuM family protein"
                     /protein_id="HHC8005352.1"
                     /translation="MNEIQFLIYEDSDKVEVLIREETIWATQKTISQLFDVGVPAISK
                     HLKNIFESGELDEEVVVSILENTTQHGAIDGKTQTNKVKYYNLDAIISIGYRVNSQKA
                     TKFRIWATDILKDYIQKGFKIDVERMKQGENAFGKDYFRELLETVRSIRASERRIWQQ
                     ITDVFAEISYDYDKNSEITKQFYATVQNKFHYAITGKTAAEIVFNGADKTKENMGLTT
                     WKNSPDGRILQSDVSVAKNYLSEKQIRSLERNVSSYFDYVERLLEDETLLGMEDFAKS
                     IDEFLTFNRYQILDGNGKISSKAAKRKAVDEYKEFNKHQHIVSDFDKEITKIEGELK"
     gene            complement(39424..42498)
                     /locus_tag="ACN3HL_000446"
     CDS             complement(39424..42498)
                     /locus_tag="ACN3HL_000446"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HHC8005353.1"
                     /translation="MTKQFGIKSQSELRFEQEVVDYLTRIGGVKQWEYKAEIKTTEQL
                     WNNFKKILEQNNQARLDEPLSATEFNQVKKIITNINTPYQAGQFLYGVNGVSEIEVDL
                     DNGKHVFLTVFDQAQVGGGNTVYQVVNQIQRPKVVDGKPNRRFDITLLINGLPIIQIE
                     LKKALHNATEALNQMEQYIAEKQFSGIFSTLQILIAMTPFDIRYMANTTLQNFNRAFA
                     FNWQDEETAHPVRSWKLFADKVLSIPMAHDLSTRYMVLDGTKNKESIKVMRPYQVYAT
                     KRVLDKVRKFDFKHDEGKLGYIWHTTGSGKTITSFKTAWLASRLSNVDKVIFLVDRIA
                     LTNQTADAYRAYDPIAGFEGKTGVVSDTANISDLHRKLTKKSDKNIIVTSIQKMSRYV
                     TRDSFQPLTENVLFIVDEAHRSTGDGTKNEGMLESIRKALPNSAWVGYTGTPKFPETR
                     EIFGDLLHAYTIKEAIADKNVLGFKVEFKETIEAPADPTEEDIDDNLRGSVYDHSPEH
                     VELVVEDIFDNWKERSNNRKYNALFTVHVGGNRASTPRAMEYFDKFMEENNKRSIEDQ
                     IKVAISFSMDTSNSSHQLKTNENLHRAIQSYNRLFGTAFDMTTVKSYTEDLARRLNKT
                     ADDGNYLDLVIVVDQLLTGFDAPELNTLYIDRTLKGGNLIQAYSRTNRIHDRDAKPQG
                     NIVNYRWPIQNEYEMNKSFAIYSNRDSAAEQLSLDELKKDNEESGILSKSFSKIESET
                     KEVIQKLAELTDNFIQLPPSEKAQEEVFEGLQEYNRLLNQLKQFTEDDEKNPVSVYDE
                     PELFYDRLGITEDQEVMLTTVLANELRERRAQIENIDISQVNLEMTHIHDVTINYDYL
                     IELIARMADEVHEDKMDQAELTKNEIDVEIAKSDSDKEITKVRNFVSKIFTKEFIFDK
                     YPAPRDVEEMNQAMEQSQKDSNIKLYTEFVRTWGLDNSVKPKDLAKLISRHRVGQEDM
                     DKQGELTAMMNDARTDYKEIAAAEVANLSWVKYRIEFRKAFYQMADETKKGE"
     gene            complement(42502..43080)
                     /locus_tag="ACN3HL_000447"
     CDS             complement(42502..43080)
                     /locus_tag="ACN3HL_000447"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHC8005354.1"
                     /translation="MEMRKLSEFVTFVQGINQSRAEKQFGNQEIDYYDQASFEEDHKY
                     YNEATQEERVNYLFDQEVSLDKRDVVISNSLQRATMVSGQNVGKVLSLNFTKVEFKSD
                     LLDKRYFLYLFNNHKDIQRQKDRGLQGTGPVLRLTKQSLEQLVIPLPLIEEQRKIGGI
                     YTESLKLQSKLSIYTRLLEQFTNSMLEKSLEE"
     gene            complement(43383..43628)
                     /locus_tag="ACN3HL_000448"
     CDS             complement(43383..43628)
                     /locus_tag="ACN3HL_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005355.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            43733..44506
                     /locus_tag="ACN3HL_000449"
     CDS             43733..44506
                     /locus_tag="ACN3HL_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005356.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(44736..44939)
                     /locus_tag="ACN3HL_000450"
     CDS             complement(44736..44939)
                     /locus_tag="ACN3HL_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death protein"
                     /protein_id="HHC8005357.1"
                     /translation="MLQEVVHSNSEIEITRDSKNGLNDGVIMISKRKWELLQEELYLQ
                     RTGTWAYVSDLMKNEKEDDFKVV"
     gene            45020..46146
                     /locus_tag="ACN3HL_000451"
     CDS             join(45020..45248,45248..46146)
                     /locus_tag="ACN3HL_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHC8005358.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNTLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(46334..46648)
                     /locus_tag="ACN3HL_000452"
     CDS             complement(46334..46648)
                     /locus_tag="ACN3HL_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005359.1"
                     /translation="MTEENKVDLLETLVINKKEFEQLFLDFFVQYDRIYDFNSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(46725..47219)
                     /locus_tag="ACN3HL_000453"
     CDS             complement(46725..47219)
                     /locus_tag="ACN3HL_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005360.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(47212..47514)
                     /locus_tag="ACN3HL_000454"
     CDS             complement(47212..47514)
                     /locus_tag="ACN3HL_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005361.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(47537..48874)
                     /locus_tag="ACN3HL_000455"
     CDS             complement(47537..48874)
                     /locus_tag="ACN3HL_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HHC8005362.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQRTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEDGLILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSEEVLTEIAIRYL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(48859..49356)
                     /locus_tag="ACN3HL_000456"
     CDS             complement(48859..49356)
                     /locus_tag="ACN3HL_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005363.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(49505..49843)
                     /locus_tag="ACN3HL_000457"
     CDS             complement(49505..49843)
                     /locus_tag="ACN3HL_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005364.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(49847..50032)
                     /locus_tag="ACN3HL_000458"
     CDS             complement(49847..50032)
                     /locus_tag="ACN3HL_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005365.1"
                     /translation="MQLILQISTQDFLELAELCDSVKKATNEKITVTNYIELMIQEEL
                     VMKNELMNELSHIQKGA"
     gene            complement(50046..52799)
                     /locus_tag="ACN3HL_000459"
     CDS             complement(50046..52799)
                     /locus_tag="ACN3HL_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HHC8005366.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFVESTGLNKVYQSVLSTIVVGLMILSLVIIGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIHSGIEFSKTFYNDTTTITNSDEGVAWSLIEQGVTDLAYINKTDQYSMINKT
                     NDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERRLSGLASDGATMASERATK
                     PFKSMRDMANDTKNKFKEGLDDGTMSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNINPASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKSVKENPQNSTSSQDRRSVDVRENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDV
                     RENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDIRENLQNTTSSQNGNRTVDVREN
                     VQSSASNQPRTIDVRENLQNTTSSQSGNRTVDVRENVQGSASNQPRTVEVRETRAEAS
                     QGDKTQKINIVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSL
                     FKK"
     gene            complement(52786..53004)
                     /locus_tag="ACN3HL_000460"
     CDS             complement(52786..53004)
                     /locus_tag="ACN3HL_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005367.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(52997..53737)
                     /locus_tag="ACN3HL_000461"
     CDS             complement(52997..53737)
                     /locus_tag="ACN3HL_000461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005368.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(53870..54745)
                     /locus_tag="ACN3HL_000462"
     CDS             complement(53870..54745)
                     /locus_tag="ACN3HL_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HHC8005369.1"
                     /translation="MAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNSQDQ
                     TNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKDSIE
                     REYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIAKQE
                     KASRLDMLETLKKIG"
     gene            complement(54915..55196)
                     /locus_tag="ACN3HL_000463"
     CDS             complement(54915..55196)
                     /locus_tag="ACN3HL_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005370.1"
                     /translation="MEQIGVSVMLNTDQTNQLKTHVFEVTKEAIDQARIDSGLERPFL
                     KGKEMAKFLNVSYGTFLKFKRLGLPIIVVDTIELYSKEEVKKWMLQHQI"
     gene            complement(55251..55448)
                     /locus_tag="ACN3HL_000464"
     CDS             complement(55251..55448)
                     /locus_tag="ACN3HL_000464"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8005371.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            55615..55989
                     /locus_tag="ACN3HL_000465"
     CDS             55615..55989
                     /locus_tag="ACN3HL_000465"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005372.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            56079..57245
                     /locus_tag="ACN3HL_000466"
     CDS             56079..57245
                     /locus_tag="ACN3HL_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005373.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(57344..57736)
                     /gene="rpsI"
                     /locus_tag="ACN3HL_000467"
     CDS             complement(57344..57736)
                     /gene="rpsI"
                     /locus_tag="ACN3HL_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HHC8005374.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(57752..58180)
                     /gene="rplM"
                     /locus_tag="ACN3HL_000468"
     CDS             complement(57752..58180)
                     /gene="rplM"
                     /locus_tag="ACN3HL_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HHC8005375.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(58714..59181)
                     /locus_tag="ACN3HL_000469"
     CDS             complement(58714..59181)
                     /locus_tag="ACN3HL_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HHC8005376.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(59301..60839)
                     /locus_tag="ACN3HL_000470"
     CDS             complement(59301..60839)
                     /locus_tag="ACN3HL_000470"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HHC8005377.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            60919..61605
                     /locus_tag="ACN3HL_000471"
     CDS             60919..61605
                     /locus_tag="ACN3HL_000471"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HHC8005378.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(61806..62333)
                     /gene="msrA"
                     /locus_tag="ACN3HL_000472"
     CDS             complement(61806..62333)
                     /gene="msrA"
                     /locus_tag="ACN3HL_000472"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HHC8005379.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(62417..63094)
                     /gene="pgmB"
                     /locus_tag="ACN3HL_000473"
     CDS             complement(62417..63094)
                     /gene="pgmB"
                     /locus_tag="ACN3HL_000473"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HHC8005380.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(63091..64221)
                     /locus_tag="ACN3HL_000474"
     CDS             complement(63091..64221)
                     /locus_tag="ACN3HL_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HHC8005381.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(64221..66404)
                     /locus_tag="ACN3HL_000475"
     CDS             complement(64221..66404)
                     /locus_tag="ACN3HL_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HHC8005382.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(66401..67426)
                     /locus_tag="ACN3HL_000476"
     CDS             complement(66401..67426)
                     /locus_tag="ACN3HL_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8005383.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(67471..68298)
                     /locus_tag="ACN3HL_000477"
     CDS             complement(67471..68298)
                     /locus_tag="ACN3HL_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HHC8005384.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(68295..69362)
                     /locus_tag="ACN3HL_000478"
     CDS             complement(68295..69362)
                     /locus_tag="ACN3HL_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HHC8005385.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(69388..70224)
                     /locus_tag="ACN3HL_000479"
     CDS             complement(69388..70224)
                     /locus_tag="ACN3HL_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005386.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(70221..71090)
                     /locus_tag="ACN3HL_000480"
     CDS             complement(70221..71090)
                     /locus_tag="ACN3HL_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005387.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(71160..72443)
                     /locus_tag="ACN3HL_000481"
     CDS             complement(71160..72443)
                     /locus_tag="ACN3HL_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8005388.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(72457..74142)
                     /locus_tag="ACN3HL_000482"
     CDS             complement(72457..74142)
                     /locus_tag="ACN3HL_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HHC8005389.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            74417..75442
                     /locus_tag="ACN3HL_000483"
     CDS             74417..75442
                     /locus_tag="ACN3HL_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8005390.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(76037..79690)
                     /gene="rpoC"
                     /locus_tag="ACN3HL_000484"
     CDS             complement(76037..79690)
                     /gene="rpoC"
                     /locus_tag="ACN3HL_000484"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HHC8005391.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(79769..83386)
                     /gene="rpoB"
                     /locus_tag="ACN3HL_000485"
     CDS             complement(79769..83386)
                     /gene="rpoB"
                     /locus_tag="ACN3HL_000485"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HHC8005392.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            84114..85082
                     /locus_tag="ACN3HL_000486"
     CDS             84114..85082
                     /locus_tag="ACN3HL_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8005393.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            85100..86005
                     /locus_tag="ACN3HL_000487"
     CDS             85100..86005
                     /locus_tag="ACN3HL_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005394.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            86002..86808
                     /locus_tag="ACN3HL_000488"
     CDS             86002..86808
                     /locus_tag="ACN3HL_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005395.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            86965..87933
                     /locus_tag="ACN3HL_000489"
     CDS             86965..87933
                     /locus_tag="ACN3HL_000489"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HHC8005396.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(88250..88774)
                     /locus_tag="ACN3HL_000490"
     CDS             complement(88250..88774)
                     /locus_tag="ACN3HL_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HHC8005397.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            89061..>90125
                     /gene="scm"
                     /locus_tag="ACN3HL_000491"
     CDS             89061..>90125
                     /gene="scm"
                     /locus_tag="ACN3HL_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HHC8005398.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        26429 a        18758 c        15545 g        29393 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gttttttcaa
     4441 accgatccga ctagataaga aacctgtaaa tagcatcacc acaccagtga ctaacatgta
     4501 actagtaaat aacagggtcg tttcagctgg cgtagcgttt aactgtgcag caatcgtttt
     4561 taagattggg tctactagac ccactcccat aaaagcgatc atacaggtag ctgctacaac
     4621 tagcgctgaa cttttcccct ttgtttcttc atttgtttgt tcttgtatat ctatttgatt
     4681 ctccaatatt tccatccctt tctctctatt agcatcatac atgatttatt ttacatgtaa
     4741 atatgcacat gtaaaacgtg gaaactttac tgtgatataa taaagaaaat aagacgagag
     4801 gtaggatttt tatgaatact ttagcctata tattattatg cgtgctttta tccaaaccac
     4861 gttctgggta tgaattgaag cagctgatca caattttttg ggaagcccat cacagtcaga
     4921 tctatacaac gcttgccaag ttagaccagc agggttatgt gaccgttttg gacaaagacg
     4981 agcactctca aaaaaagatc taccacttga ctgatgaagg acgtgctctt gtagaggaat
     5041 ggatcaaaga ggaaactccc gctcctacgc aaaaagatga atttctagca aaaatctatg
     5101 ctttttcgac gctcgataaa acaacagcta ctggactgct attcactaga gaacaacagc
     5161 tgaacaaaat catgcaaaaa aatcaaaaaa aattgaatga cctctcgcta gacaagaaac
     5221 aagaatttgg acgttatgtt gtgatccagc gcagaattat gctttgtcag caggaactcc
     5281 aatggtgtca gcaagtaaga gaacaaatgc agcagttttt tgagtaaggg ataaacagaa
     5341 cctttctaga aatatctatt gaagagcaaa ttatcttcaa taaaagagca atacagttgg
     5401 aaaagaaaaa gcgatccgaa cgacaggcca aaacctatcg ttcggatcac tatttttcta
     5461 gaactgcatt caagagacta tgacaaaaag catgccaagg ccttttttca aataacagtg
     5521 ttccatcatt cattactttg aattgctttt agcacacttc ttgaaagcgg gccaacgatg
     5581 atcaactgca acggtaaagc ggcaatcaca ttcattttcc aagcattcat ataagcagag
     5641 aataattgat caggtattcc ttgttccatg atcacaccga ataaagacat acatgtcacc
     5701 attcctaaaa ccatcaagca tgaaatagtt aagatcattt ggaccttgct ttctggattt
     5761 actggtagtt taaaggcaat ttttttcgcc agcacaccga tgatgaagac atccaaaatg
     5821 aaagccacca cgaatccagg cactagacca atcaacaaac ttgataaatg aagatcttga
     5881 tgcagccata aattatacgc gctcatcccc aagaccatca aaaaacacat cattgttgta
     5941 aaaattattc cttctttttt atttgtaggc aatctgtacc actcctttaa atttgtcacg
     6001 aaaatcatcg tagcacattt aaaaatttct cgtaagtact ttttttattt tctgcccttt
     6061 tatttcataa acttcatcag ccgtacgctc gacaaagtaa gaatcatgag aagtaaacaa
     6121 aatcgttccc ggatatattt gcattagctt ctctaaagct tcgatcgttg ccatatcaat
     6181 aaaattagtc ggttcatcta acagcaacac attacttggc ttagtaaaaa gcaaagcaat
     6241 cgtcagacgg gtcgcttctc ccccacttaa tgtacataac ggtttcgtca aagtttcctg
     6301 agcaaaccct aagtgattca gcaaactacg gacaagcgat tctgaaaact ctgtttgtct
     6361 catgacaaaa cgaatgatgg attcttcaga tgtcatttga taaccctttt gctgatatac
     6421 ttgaaagctt actttcggag agagaaggat tccttctcct tgtttgcgga tatgttctaa
     6481 taaggttgtc ttacctgaac cattttcacc gacaatcgcg atttttttac ctaaagaaaa
     6541 ctgaaaatca ccatttacca gtaatgttct cccacttctt tccaattgga cattttgtcc
     6601 catgatggga tagcggctgt ggagttcaag agattttggt actggaaaac ggatttgttt
     6661 catctgctgc ggcttggttg tttctcctat tttttggagt cttctctcta atgttttcgc
     6721 attcttttgg atggcttttt gtacactgtc tttttgttta gaggaagaca accgatccgg
     6781 tctgatttgt tgctttttct ttttactgga cactttttcc aacttttccg cttgtttttt
     6841 cttttcttgg atcgattttt ccaatcgttt tttctctttc atgatcgact ctgcttctcg
     6901 tagctgagtc tttttctcca attccttttg agtgagatag gcactataat tccccgaaaa
     6961 ctctcggatt tctccgtctt ttacttccca gattttcgat gctagctcat ctagaaaata
     7021 gcgatcatga ctaacaaaaa ccagcgtacc ataataataa cgaagctctt caatcagtcg
     7081 atcaatactt tttctatcta gatgggttgt tggctcgtct agaagcatcc cttgttcata
     7141 agaagaaaga agacgtatca actcgatctt tcgttcttcc cctccgctcc atttccgctc
     7201 tgaagtttct tccagtctta actggaaatg actggctaat tccaaattta ggtcctttgc
     7261 ttcagcgaga taggttaatt gaggcaggta gttgaaggtg atctctgttt ggattttccc
     7321 atgatcggga aaaagttcac cggctattag tttgagcaaa gtcgatttac cgacaccatt
     7381 ttctcctatg atccctatac gatcttgctg atagacacga agagaatcaa tagatagttc
     7441 tagctggttg ccaaagctga cttgtagatt tgttatattt actgctaaat tttccatatg
     7501 ttttacactc ctatttcatg taaaacaaca attatcgata ctaaaaaaga gcagaaaaat
     7561 ctgtttgcaa aaaaactgca tcacatcttt tcctactctg aacgaaataa ctatgactaa
     7621 atcaccaaat ctgtcatagc tttcacctat tctactgtcg ttcgaaaaaa tggacatact
     7681 ccatccatga aattgttgtt tatacatgtc ttttgaattt atttagttgt tattcaaaag
     7741 ttcgaaacgt aatttcatcg atgcagtcat ttttccgacc tcctttttta ttaggttacc
     7801 acacacgatt caaaaaaagc aatagctact gaatagtaac tgaaaacctt ttattcgaac
     7861 gtagtgatct tttctggtgc taaacgaaca gactcgtaac cttcttctac cgcttttcct
     7921 attgataaaa taataactgg aacataacgg tctttatcca aaccaaatgc ctctgccaac
     7981 tgatctgctt cgaatccacc aattggattt gtttcatagc catgatcacg cgcaactaac
     8041 atgaattgca tagccgctaa gctagaatcg actttgacta catcgttcat ttcttctctt
     8101 gaaaaactct tgtaataagg aatgatcgca gctaattgtt gatctctgac ttcttttggc
     8161 atcttccctg attcgtaagc ttggttatag atttcttcgc catattcgta acattgcata
     8221 tcgccaaaaa tcatgaccat tgcagaagaa gtatcatttt gtctcgtatt gaaacggatc
     8281 aaaggacgca agatttcttt tgcttcctcg ctttcagcga ccacaaagcg ccatggttgc
     8341 atattgacag aagaaggtgc agtcgtcgct tctttgatca tttccagcat ttcttcgtgt
     8401 gggattttgt atgtttcatc atatacgcga acggatcttc taccagtcat aattgttgaa
     8461 aaatcatttt tttgttccat tattattaac ctctttcgtt tctgttgtta tattgcaaag
     8521 ttgggtattc aatttatcta aaagtgttag aaattgtttc atttctacat cgctgaaagc
     8581 cggggatagc acggaacctg tatctttatg gtccatttca caatgctcga ttttcttctg
     8641 ggctttttct gttagcgcta catacacttc ccggttgttc tgaggatttc tctgacgcga
     8701 aacatagcca tttgcttcca ataccttcag atgacgagta actgctcctt gatcaatctg
     8761 caacttttct tgcaaactgc tttgtagcaa tggattttct tctttcagtc tcatcatgat
     8821 ctcgtatcta gtaagactta taccgatatt ttcttcaaag atctggacga ttttttgatc
     8881 ggctaatttg atttgatata aaaggtgact aatctcttct aaagacataa tttcctcctt
     8941 tctaataatt gactcgtcaa cgattgactt gtcaataata gaataaaaaa agaaaaaagt
     9001 caaagaatca gctgtgtaat aaaaaaaacg ctctcaatag aaaagtatag agaaaagaaa
     9061 ttttttgtag aatgaacgga aaaaatgata aagaaagcac aacgctaaaa ccaagattat
     9121 tgattcttat caaactatag aagatagctc ttctgcagta gaaaatttta caccgccaaa
     9181 aatttccgaa atcgcctttt gcaagaatcc cgtcgaatat tagaaattgg atcagtatgc
     9241 ttaaacagta ataaaaaagt tatgacaaga tgttgtcaca accttttttg agtaaacggt
     9301 gttcaaaaac ttgcatctgc ggtaataagt tcaaccaaac aaaaaacatg aaaatctgtt
     9361 tttgtttggc tgttcttact acttgatgca gggcagcttt ttcactacct ctttttaata
     9421 accataaaat cctattcctt catatctcca gcccatcggt gttagccaat ctctttcctt
     9481 agcactcaag gtatagtgat gggtaccagt tttttcattt ggattaaata gtcgataaat
     9541 tggcttggaa ccaccagaat aaaaacttag accttcataa cgccaaccga tttttgttaa
     9601 agagttgatc tcagattgtg ccattgtgta atgatggtct ccactgtaag gattgtataa
     9661 acggtagaca ggttgtccgc tgtttggtgc ttgccaagca atcccttcat attcccagcc
     9721 tacagttggc agataatttt tttctccggc attcaatgta tataaatgtt ctcctgtatg
     9781 acggttatac agacgataca tcggagaagt tgaagttggt gctgtatcat actgtgtcag
     9841 attataggtt tcgattacat tgttcaatgt agaaccataa ttaggcgcag tggcataacg
     9901 acctgttagc caagccgtag catctttgta agagttcgta ttgcttttcc atgcaccgga
     9961 atagtagtaa acgcctggct gaaaagaagt cgtcttcaat accgttacgt tatcttgcaa
    10021 tgattctttg tacgaaggat attttctaaa agcggcattc accgtaatcc attgcccatt
    10081 cacatattcc gaagtaggca tcgtaacaga ttggccatta tagcttcctt taatcccaaa
    10141 tagattgtaa ttaggggcag aagccaaagt actgttcccc cagccacttt caacgatggc
    10201 ttgagcaatc atgactgatg catataagtc attggcactt gccaaacttt gtgcagttga
    10261 ggcaatacta tcaatgaacg cttgttgaga attagcagat gagcgagcat aaaaagcata
    10321 gccagtatag ttttcgaatt cagacaaatc tgcttgatgg gtatgtgtca atgtttgccc
    10381 atctgtcaat tggttcgtga tttcttctgc attctctgga ttgttctgag cttctgctga
    10441 tgtactgtct tcggtttgtg tttgttctgt tgtttcagtt gttggttctt cggttgaaat
    10501 tgtattttct gagacagtag ctgactgcaa agtactctct gtatcgtttt caattcctgt
    10561 ttctgaagaa ctcgatgtct gagttgcgac agtttctgtc gattcttcag ctagcactgt
    10621 tgtgttggca actgctagat ttcctaaaag aataacgcta aataataaat tctttgcttt
    10681 catctttttt ctcctttgaa ttatgaaact tttcctaaat aacagtgtaa ctaaaaaagt
    10741 aaaagcaagt caatgtccat atttaaataa catttgtttc tttttgataa atttgctttt
    10801 tctacataaa aagacgtaaa tgaagaatat tcttctccat tcacgcctta aattgatggt
    10861 cgtttgaata actatttaac aagtaattct ctttggatat tatccgttat ggattatact
    10921 tcctgtgtcg tcggacggat aatcatgtta ctgacagaca tccggtctgg cgtttctatc
    10981 gcaaatgcta cagcagaagc tatatcttcg gaggtcaatc cccattcttt ttgcgcttca
    11041 tgaagttcaa gagcagcctt tttgtcgctg atggtttgat ataattcagt ttgaacagct
    11101 cctggagaga tgatcgtaga tttgatgtta ttttgccgtt gctcttgacg taatccttcc
    11161 atgattgcac ggacagcaaa ttttgttccg caataaacgg cggaatcagg ataaacaaca
    11221 tgtcccgcca cagaatcagt tgaaatgata tgcccagatt tttgtttttc catgattgga
    11281 agtacggcgg aaattccatt taacacaccc atgatgttga tatcaagcat attttgccat
    11341 tcatcacggt gaccttcaac taatggagcg gttggcatga ttcctgcatt attgtacaat
    11401 acatcgattc gaccgaactt ttccatcgct aaatcgataa ctgcttggac ttgtgcaaaa
    11461 tctcttacat ctgctgtttg aatatatagc tcagcttctg gtaaagattc ttttattgct
    11521 tttaggcgat cttctcggcg tgcagctata actagtttag cccctttttc tgctaatagc
    11581 ttcgttgttg cttcaccgat tccgcttgaa gcgcccatga tgacaatcac tttttctgat
    11641 aaatcattca ttctattctc ctcctgtttt gaaaaatctc ttgcttatac tcactatctc
    11701 ttatttcatc ttactgttca aataatccgt tcgacaggtt tgacgatttt ggcagggatt
    11761 cctgcaacga tggtattgtc tgggacatct ttcgtaacag ttgcattcgc tgcaacaatg
    11821 gcattctcgc caatcgttac gcctggcaga atagttgctc ctgctccgat ccaagcattt
    11881 ttcttgatgt ggattggctt tactgacaag cctcttcgtt cttttggatc ggttagatgg
    11941 ttcaccgtga tgaggttgac acgaggacca atcaatactg aatcttctaa acagatgcca
    12001 cctaagtcaa cgaacatcac ttgacgattg ataaagacat ttttccctat actaatatgt
    12061 ttgccgaaat ctgtataaaa aggcagcaga acagtcaccg tatcatctac tttgtcacta
    12121 atgatatttt ctagccgttt gcggatatct gctggttcat ggtacccagt attcagcgct
    12181 gctaaaggct cttcgttttc agcttggatc tgatggatca cttcaaagag cggatccgtt
    12241 actcgaatct ctttattgac gatttgtttt tcgatgaggc ttgtcatttt gctccctcct
    12301 tttatcctta ctttataacg gacggcttat catgtctaat acttataaaa catacttaac
    12361 tattcctttt aactatactt agtggtatgc ttttttaaaa acaggaggga aaaaatggat
    12421 attcgtatac tgacgtattt tttagcagta gctagagaaa aaaatatcag ccgagcagca
    12481 aaatctctgc atatcacgca acctactctc tcaaaacaac tgaaagattt agaagaagaa
    12541 cttggtgtga cacttttcac tcggggctcc cgagagatac agttgacgga ttctggtcga
    12601 tatctttatt caaaaggaaa agaaatcttg tcgttggtag aaaaaacggc gaacaattta
    12661 acaaatgacg caatcatctc tggagaaatc tacattggcg gaggcgaaac taaagcaatc
    12721 tctttcattt ctgatagcct tcattcgttg atcaaggcgc atcctgatat ccagtttcat
    12781 ttatatagcg ggaatgcaga tgatatcata gacaaactgg atagcggatt acttgatttt
    12841 ggactcgtaa tcgaaccgac aaacaaacaa aaataccagt catttcgact gccagcccaa
    12901 gatcgttggg gacttttgat acatcgaaat catcctttag caaagcaaac cgtcatccat
    12961 ccgcaggaac tgaaaactgt tcctttgatc atttcccggc aaacgtcagt ggacagtcaa
    13021 ctagctgaat ggctaggttt cagcatagat cagttatcga tcgtcggaac atataactta
    13081 ttgtacaatg cttctttgat ggtcgataac gggacttttg gtgcattagc tctagatggg
    13141 atcatcaata cttatgggac ggaaaaaata ttcatcccac tcgatccgcc attacaagct
    13201 tcactgaatc tcatttggaa aaaagaccag cctctttctc ctgctgctcg taaattttta
    13261 gatgtcctaa cggagaaata cagttaagta gagttttttt ccttcgcttt cagcttttta
    13321 acaacgaata agataagcaa aagatccaac gattaaataa cataagtttc ttaatttatt
    13381 tcttcctttt atttctgata attccagtaa attactataa ttataaaaaa agaattgaca
    13441 aaacataact gtctatataa aattgattac gttaacaata attcgtttca tgtgactaga
    13501 tcatactagg catgaaaaat ctctgaggaa catggtttcc ctaggaggtt tttcgtgtct
    13561 atttttgttt ggccgcaatc aactggtcta gcaaacgtga aaaccaaatc ttcaaaaagg
    13621 gtgcgcgcat gaaaatcaaa aagatcttta atcaaaatgc agtattggta gatgacggtg
    13681 gacaggaaaa agtagctatt ggaaaaggga ttggatttga cagaaaaaga aatgatttga
    13741 tttttgatcg tgatgtcgaa cggatatttg tcatggaacc agaaggtcaa atcaagttgc
    13801 aaaatttact taatcagatt gatgaacgct ttttatttgc agcagaaacg atcattgatc
    13861 atgcggaaac tgttttgatg gaaaagttga atgaacatgt attgatcgct ttgaccgacc
    13921 acattgcttt ttctgcggag aacattaata acggtatcgt catccgcaac aaacttttaa
    13981 gagaaatcga agtgctttac agtgatgaat tcagtattgc tcaatgggca gtagagtatc
    14041 tgacaaaaga gcttgggatt ccatatactt atgacgaagc aggatatatc gcaatccata
    14101 ttcacagcgg acgaagcggt cggaacaata accatcgcag tatccgtgaa gtgacgattg
    14161 tatctgacat catccattta gtggaatcag aattggaaac agatatccat tcagaaccat
    14221 tttcactgaa ttattcaaga ctggtgaatc atttacgact gcttctacaa cgaacccatg
    14281 cgcaacaata tgctgtttta gacacggaaa tcgtagaaat ggtcaaacga aaatacccag
    14341 aaagctataa gatttctaaa aaaatccgtg tgttgctgac caaagaatac cagctcgcga
    14401 tcacgaaaga agaactgggt tacttggcca tccatatcga gcgtttaaga agcgcaatcg
    14461 tacaaacaaa tgttaacaat catgaggagg aaaaaaattg aaagcatatc tacaacgaat
    14521 gggacgttcc cttcaacttc cagttgcggt cttacctgct gctgctttac tagtagggat
    14581 cggaaactgg tgggcatctt atagtaacga cattgtcgct cattttttac aagctggcgg
    14641 taacgcagtt ttaggtcaat tacctttgct gtttgccgtt gggttagcac tagggatgtc
    14701 agtggacaaa tcaggtgctg ctgccttggc aggtttggtc gcatttgaag ttccagtaaa
    14761 tgttttaaaa actgattcag tagctacttt attgaatatc aaaccagaat cagttgatcc
    14821 atcttttgct cagatcagta acgtatttat tggtattatt gccggattga ttgcggcagc
    14881 tctttataat cgtttccacg aagcaaaatt accgatggct ttatctttct ttagcggcaa
    14941 gcgtctagtg ccaatcttgg ctgcctttgt catgttgctg atcagtgcag tgctactgct
    15001 cgtatggcct ccggtttact ctgctttagt ttcttttgct aaattcattt tgagtttagg
    15061 ctggggtggt gcaggtcttt atggcttctt caaccgttta ctgatcccta caggattgca
    15121 tcaagcaatg aactccgtgt tctggtttga cgtagcagga atcaatgata ttggtaaatt
    15181 tttggcttct gaaggaacaa aaggcgtaac aggaatgtat caagctggat ttttcccaat
    15241 catgatgttc gggcttccag caggagcata tgctatttac agaaatgcac gtccagaaaa
    15301 caaagcaaaa acagcttcct tgatgctagc agcagctttt gcttcattct ttactggtgt
    15361 gacagaacca cttgaatttt catttatgtt cgttgcttgg ccattatatg tcttgcatgc
    15421 aattttcact gggatttctt tagcagtgag tgcattcttc cattggacag caggatttgc
    15481 ctttagtgcc ggatttgtcg attacttcct atctttgaaa aatccgattg cgaatcagcc
    15541 attgatgttg atcgtccaag gattagtaac agcagtgatt tactactttg gctttaactt
    15601 tgctatcaaa aaattccatc tgatgactcc tggccgcgag gaagcagatc tttcagatga
    15661 cgatactgca acgactaatt cagacaataa atatgcggca caagcaagca aaatctacgc
    15721 tgcattaggc ggagccgaca atgtaacttc gatcgataac tgtactacac gccttcgttt
    15781 gcaagtcaaa gatacaggcc tgatcgatca aaataaaatc aaagccactg gcgtacctgg
    15841 tatgaagatc atcgacggaa aaaatgcgca agtcatcgta ggtacagaag tacaattcgt
    15901 tgcagatgag atggcaaaac tacatggtgg tgctgcagca cgacctgcac aaacaaacac
    15961 cgtggttaaa acagaaacat ttgccggtga aacgatcgaa caagatattt acgctatcgc
    16021 aaatgggaaa ctgattccaa tcactgaagt ttcagatgat gtattcgcgg aaaaaatgat
    16081 gggtgacggc tatgctgtat taccagaaaa tggagaaatc ttctctccaa tcgctggtac
    16141 gatcacaaac attttcccaa cgaaacatgc tgtcggaatc caaacagatg ctggtatcga
    16201 agtcttgctt catatgggca tcaacactgt tgacttaaaa ggcgaaccat tcactttata
    16261 tgtagaagaa ggtcaaaaag tcgcaagagg tcaattgatt gctttagttg atcttgccgc
    16321 tattcaatct gcaggcaaaa acacggatat ggtcgttgta ttcacaaatg gcgacaaagt
    16381 ccaaagctta gaaatcgaac ccgcacgtga tgtaaaagca aatgataaaa tcggctctgt
    16441 ttccaacaaa gcctgagcca tcgtcttccc cagacttttt tatcgataaa caaacaggag
    16501 ctgagacaaa aatcttgtct cagctccttt ttccgaataa aaacggcgtt ctcctgccaa
    16561 ctccgcggta ataagtccag ctaaacgaaa catatgaaga gctatttttt atttgactct
    16621 tcttattact tgatgcagaa cagctttttc acaaaatttt tcttcatact caaaactaat
    16681 cggctttttc acaacctctt tatacattat tcctgatcca atatttcttt taatgctgct
    16741 tcaagagaag ttaatggttt tcccaatact ttttctaaat catcagagga aatagctaac
    16801 tgatcctttt taatatcatg ttggatcgct aaaaacatgt cagctgcttc ttgagggaat
    16861 ccggcttctt ttagattttc gacaaacgct gcatcacttg cttcaataat ttctaactct
    16921 ttacctgtcg cacgctctaa tgccttggct aattcttcat agtcagttag attgccggat
    16981 aattctaaga tttctggaga gtcactttct actagtactt ttgctgcagc ttctgcatat
    17041 tcacgtttca atgcccaacc tgtttttcca tttcctgcag cataaacgaa ttgaccagtt
    17101 tttaaagcct gcccaatgat aggtaattca ttctctacat accaattatt ccgtaaaaat
    17161 gtatgggaaa tacctgaatc cttaatcatt ttttcagtga attggtgatc tggcgctaat
    17221 acactgatcg agtgatcggc atctgcaaaa cttgtataag cgatataaga taccccagct
    17281 gcttgtgctg ccttcactac attcttatgt tcggcttgac gatttcctgg aacgccagag
    17341 acaaaaagca atcgatctat tcctttcaac gcttctttca ttgagtctaa atcatcataa
    17401 tcaccaatac gtatattaaa tccagcttct ttcagtgctt ctcctttttc ttcactacgt
    17461 actagtacat agatttcatt ttgtggaacc atctttttta agaattccag cgcataacca
    17521 ccaaaacctc cagttgctcc tgttactaaa taatgcatat ttgccactcc ctattctttt
    17581 tatttgttaa gatttacagc tgtacattta taaattacac ctttatcata aagagtgtgg
    17641 taagataagt caagcaaaaa aaatgaaagg atgacaactg atgaagtatt ctctgcaatt
    17701 tagtgatgca atccatgtac ttgcctatat tgaaatgttt caagataccc gatcactttc
    17761 tagtgagatg attgccagta gtatcgaaac aaatgcagca aatgtacgta aaatcatgag
    17821 tcagctcaaa aaatccggtt tgatctttac aaaaaccgga aaaccgcagc cttcccttgc
    17881 caaaagtcca gatcagattt ctttactaga tgtctatcgc agcatcgaag gtaatacaca
    17941 gcttatccaa gtcgatccaa aaacaaatcc aaattgcgtc gttggtgcga atatccaaga
    18001 agctttagaa gaaagctacg ctcggctgca gaaaaaggca gaagaagaaa tggctaagat
    18061 cacacttgat agtctgatac ataaaatagc cgttttggaa aaagaaaaaa gaccagaaaa
    18121 cacaggcctc gtagagagat ttttataatt ctctctactg tgcctgcatt tttctgatcg
    18181 gaatcgtcta cataaattct tttattctcc gggggacaaa agccttgtca tgcccctttt
    18241 tcctctctaa tgctcaggtc aaagcgctga agtcatgacg tcttgataaa cggtgttcaa
    18301 gtagctgacc ctcggcatta gttctgaaaa atgcaaaata tggaaagcta tttcccattt
    18361 ttcctctcta atgctcaggt caaagcgcta ctttcacgac ctctatatta tcatggttta
    18421 ttgactaccg gtatccagat ttctcccata tatttcccgt tggtaactcc catttcgact
    18481 acagcatttg gacccccaac ataggcgtaa tcttctactt ctcttaaaac atgcccaaag
    18541 gccgtattcg tcaaatcatt tcttaattct tcaggcgatt ctgctaaagc gcttacaaca
    18601 agatacgttc cttttgggaa tgggatgatt cgcgtagtgt ttggaacatc ctgactcgtt
    18661 tgaacaccga catagtacat cattttcccg ttatagggtt cgttgactgt aaagaaataa
    18721 tgattttcag cagcttgttt caatgcatct attgttccat taccgataac tttttgctca
    18781 aatgcttgtt tctctgcagc caaaccgaca aaatccgtat tgctactctt caattccaca
    18841 ccaatacccg tcaccgtaaa atctggtttt tcttcgatcc tatactttgc catttctccc
    18901 accctttcta ttatattaag ttcatcttac ataaaattaa agggaaatga cacgattacg
    18961 ctcttttttc tagggatatt tttatttttt aactattttt ttgctttcac tgcaatccaa
    19021 atctcactgt aaacattact gaaatcctct ccccattttg taaaagagat ctcgggagct
    19081 tcgactaacc cataatctga agaaggaagc cattctgcat agattttccc ccaagtatct
    19141 tgtaaagttt ggggaaatgg ccctttatta ggaaaaatgg cccaagtgtg ttcttctata
    19201 gcaagcattt ctaaatcagc gtacggattt tcttttgtcg tagcaaagcc aatcatgtgc
    19261 atcaaactgc ccttttcttc caagcggtct ccatcaaatc cataagaaac gttgattact
    19321 tgatttggat ataaatctcc taacttatgc atctcttccc tttgagtctc cgtgatcgtc
    19381 tgcgctaact tttgtatttc ttgattgact ccttcaaatt tgacaggaac ttttttcgcc
    19441 acacctgcca cataaaactg ttctttcttt tcgatacgaa attccatcga ttttcctcct
    19501 ctgacatcaa taaaaaatgt caagcgtgga aaagattttt gtatgccgta tctactgatt
    19561 tctgaaggca gatatcctga ccaatcacga aaagctcttg aaaaaccttc gactgtttca
    19621 tatccatatc taaacgccgt ttctgtcact cttgatccat ctagaagatc gcgattagcc
    19681 aaagccaatc tacggttttt gatatagtcc attagcgaca tccctgcaat aaacgtaaag
    19741 atgcgtttta attgatattc agagattcct gtattttcgg ctattatttt ataggaaagt
    19801 ccttctgtca aatgttcttc gatgtaatcg atcaattggt tcagatcttt aagcatattt
    19861 atcttcctcc ttgattgcct ttttatcata ttatcaaaga aagtcaatta cttgatgaat
    19921 caggaaccaa tttagtcaga tgtagaaaat gttgtatgga tctaaagaaa attctcaagc
    19981 agcgtttcgt aacggataat tggtattatc tgcctatcta tgttttacct ttagaaaaat
    20041 aaattttggg gaagacagat tctaagtaaa caaagcggta aaaatatctt ttattccctt
    20101 agttaatccg cttactacct actgtacaaa gcaaattgtt gttcaaactg ctgatcagaa
    20161 cgctgcttgg atttttcttt gcgatacatc atacctcttt tatcaattgg aacaattatt
    20221 tatttctaac aaaatcactt catttttgtc agataaataa aaaacaaaaa aagttccatc
    20281 tttaaaacac gctattcttt tactttttct cacattctct aagaaaagaa aaggagaatg
    20341 aatttttgac aattcgagca aaagtgatta tcaaatatgt aaaatcagct acttttttct
    20401 taaacgtttc tttatactaa atataaataa gtgtttcatg aaaggagaac tagatgaata
    20461 attggcttga gtattttcct gaaaacgttt tggaacgcgg ttacagctat catctgcacg
    20521 gttttgtccg tcatttgaac tatacaagca agtacttgtc cgcaacagtt tctggcacgg
    20581 aagattataa ggtagtgatc acttgggatg aaaagaccaa catgacttgt gattgtctat
    20641 atgccataga aggaaaaaaa tgcaaacaca tggctgctgt cttattcgct tacgaagaac
    20701 gtccaataaa aaaatccaac tactcacttt ccgaactctc gtcccttgtt tcctccgcta
    20761 gttcctctct tgtacgggag cttttaacag agattcttat agaacatccg cactttatcg
    20821 aacgcttcaa agttaagatg ccatttcatg caataaatta ttcagataaa ttaacaacta
    20881 tcatccataa atacgatcat attatcaaga aaaacaaaaa caggaaaaca gcgaagttca
    20941 tcatggagat gcgaaagttc atccaagaag cagttgaatc gcttattcag caaaatgcct
    21001 atcttcccgc attcgaattg atcaatgaag tgattgctac tctcgaaaca ttctattggg
    21061 agcctgagga tgaacgaacc cttcttctga tagaggactg ttattattta tggaaagaat
    21121 tattagcaga agcacctcat gcagaaaaaa ggcaaatgtt ctcttggttc gtctgccaag
    21181 tcgatcatac tgacgcctct tattcaaaac gctactctat aaaaatcctg aaagaagact
    21241 ttcgggaaaa agaattttct aaccaaaaga aaaaaataga taaaaaacta aagaaacggt
    21301 aaagaaagac gatttcaatg aaaaatagca agtaaacgat aacaaccatc ctaaatccac
    21361 aagaaataca gcagaccttg ctttaaaaac acgaatcatg caaaggatga agtaaagaag
    21421 acttaacgcg tacccaatat tagtcatttg actattaggt acgcgttttg ttttataagt
    21481 catgacaaat ttccttcgtt gctggataga ttttccggca ttgttgatag attttatgat
    21541 acttttctac attttgtaag agaggttccg ctgcatctgt atattggata aaattctgac
    21601 aacaactttc aggtgtgtcg aaccacccta accctagtgc agcaatcatt gttgcgccta
    21661 atgcaggtcc ttcctccata cttaaacaat agaccgttgc atcgaaaata tcagcttgga
    21721 tttgtagcca tgcaagattt ttcgcgcctc ctcccaccga aacaatacgt gtaaatctgc
    21781 gacccgctag ttctttacgt ttcaatccca ccattgacaa atgctcatta aaaatttaga
    21841 atattcacaa gtttaacgac aattatgaaa atttatgtcg tgctaaagga gttttgttat
    21901 tggatgaaaa gttagatata aaaactgcga tcaaagacac gttacctacc gttttcggtt
    21961 atatcggtat tggacttgca tttggtatcg ttgggaaagc tgccggattt catccactag
    22021 tcgtcacgtt gatgtccctg ctggtctatg ctggttctgc ccaatttatc acagtcagca
    22081 tgcttgctag tcacagccca ttgctttcca tcgttttctc gacctttcta gtcaattccc
    22141 gaatgattct gatgagtatg acgattgctc cttatttcaa gaaaaatcgg ctgcttcaaa
    22201 atctgctgat tggcacattg ctgacagatg aaagtttcgc actgggaatg aataaattga
    22261 actatactgg acaaaagtta aactttcgtt ggatgaatac agctaattgg atttcttatt
    22321 tgacgtgggt gggttcttct cttgttggcg cacttttagg gaattttatt actgatccga
    22381 aaaagtttgg tttggatttc gccatcgtcg ctatgtttat cgggttactt tatcttcaag
    22441 tcatttctga tagaaacacc tctaaacgat tacagttgat cctgattggt ctcactttga
    22501 ttctggtata tgtcggactg atttttatcc caagcaactt agtgattgta gttgtaacac
    22561 tgattgggtg cggattgggg gtgtggatca aacatgcctt cttttgagtt tacattgctg
    22621 actattttag gttgtacttt agcaacttgg ctttctaggg tcctaccatt tgtcttactg
    22681 aaaaaattcg atttaccgca accgttgctt gagtatttaa gttttgtccc gatcgtcatt
    22741 atgtctgctt tatggttcag cagtctattt acccaaaata tcggacatct gccgcagatc
    22801 aatctcgaaa atgctttggc ttcagttcct acacttttag ctgctattct ttcaaaaagc
    22861 ttattggtga tcgtcttggc aggaattctt tccctttcgt tgattcgctt attataaata
    22921 aaaaaacaag agcttatggc aaattactgt catgcgctct tgtttttatc aaagtcaaat
    22981 aagaaaaaaa tcggcgtatt cttgcttatc cgttgaacgg accactaaca acgacttttc
    23041 ctaacatatg tcctgtttct acgtctttgg ttgcttgttt caagttcttc gcattcatcc
    23101 catctgaata gaccttgctc aatgtactgc ggataatccc ttcatttgct aaagcagcaa
    23161 tgtgcgctaa agcttctcct tgcgtttcga tttcatagtt atagtctgtt ttagcgaaca
    23221 tatactccca gtcgaagctg atagattggt ttttccaaac acctatatct aacggctctt
    23281 tgatccctac gatcgttccc acatgtccaa atggtcggac aaggtgcttg atttgatcaa
    23341 agtagcgggt aatatcgaat aatacagcga catactctac ttgatcgatt cctaattcac
    23401 gaaaactttt acttaagtcg tgatgataat cgattggata gtctacacct gtttttttca
    23461 gccattcaaa attcttcgga cttgcagtcg cgtagacttc taggccagcc caatgcgcta
    23521 gttgattcaa aatcgaaccg acgcccccgg atccgttgat cactaagatt tttttcccgc
    23581 gattggcatt ttcttctgga gttagaccaa atttttcaaa taacaattca taagcggtca
    23641 atgaggtcaa cggcaaggct gcagcttctt catctgaaag attttttggt gcaagagcga
    23701 caatacgttc gtcaactagt tggtattctt gattgcttcc tgctcttgtt gttgtacctg
    23761 cgtaaaaaac gcgatcgccg acagaaaatt tttgcacttc gtcacctaca gcaacaactt
    23821 tcccgactcc atcaaaacct aagatacgta aagcatttct tatcccgtta tcttggcgaa
    23881 gtttcgtatc gacaggatta acagatactg cgttgacttt taccagaaga tcccgtgaac
    23941 tgggtacagg tatctgttct ttttcatcaa taaagctttt tggatcatcg atcggcaacc
    24001 cttcataaaa accgactacc ttcattaatt ccttttctga catacgaatt cctccttagc
    24061 ttcatcaagt tggagcatcc atacagtgtt catttcaata tatatagtat gctatttgtt
    24121 ccaccttttt tattcatcat aattattctc ttacttaaag taaactattt gcactttttt
    24181 ggttaaaaaa gaggttgcga caagactttt gtcacaacct cttataaacg gtgttctcct
    24241 accaactctt cggtcacaag tcaaaatatt catcaaacat gagaagctgt tttttgaaat
    24301 tgctccttgt gactcagagt taaacggcag gctcacaacc tctgatataa acggtgttca
    24361 atcaactgac cctcggtatt agctcaaaaa acgacaaaat atgaagagct atttttgttt
    24421 ggctgttctt attacttgat acaggacagc tttttcacga cctctaattc acggtgttca
    24481 agcaagaaat cattgttcac tgaaaagcgt tggatgttct ttttcaaagg tctctaagat
    24541 ctctcgtact tcatcagtag atttcgtatt catcaactga actcgcaagt catttgctcc
    24601 tggaaatcct ttgatataga ttttaaagaa acgatgtagt cctgtgatgg aacgcgggat
    24661 gatttctgaa taatgatctt gcagatctag ttgcagacga agtagtccga tcagttcttt
    24721 ttctgtatgt tccctcgggt ctttttcaaa tgcataagga ttcttgaaaa tccctcggcc
    24781 aatcatgatg ccatcaacgc catatttctc ggccaattct tctcctgtct ggcgatcggg
    24841 gatatctcca ttgatcgtga ttagtgtttg tggagcgatt tggtcacgta aagcaatgat
    24901 tttaggaatg acttcccaat gtgcatctac tttactcatc tctttacgcg tacgcaaatg
    24961 gacagaaaga ttggctatat cttgatgaag taggtgactg atccattctt ccatctcaga
    25021 catttccgta tagccgatac gcgtcttgac gctgacaggc aaaccgccag ctttagctgc
    25081 ttcaatcaat tgtgccgcta cttctggacg aaggatcaag ccactgcctt ttccacgttc
    25141 tgctacatta gggactgggc agcccatgtt gatatcgatt ccttggaagc ccatttctgc
    25201 catagcaatg ctcatttctc taaaaaattc tggcttgtct ccccaaatat gggcaaccat
    25261 cggctgttca tcttctgtaa atgttaatct tcctcgtaca ctgtcttttc catctggatg
    25321 acagaaactg tctgagtttg taaactcagt aaagaagaca tccggtgctg ctgcatgctt
    25381 tacgacatgg cgaaatacaa catctgttac atcttccatt ggtgctaaaa caaaaaaagg
    25441 ctttggcagc tctttccaaa aattagtagt catttatttg ttactctcca ttctatcaag
    25501 cagtgaagtc gcaatctttc tcaaaaacat tgtcattata ctaggaaaca aaaaaagaag
    25561 caaagtgaac agcttaaaag atgtttctga ttgagcaaaa aaaagactgt gacaaaaatc
    25621 ttatcacagt ccattttccg gaataaatgg tgttcaaaag cttgcatttg cggtaataag
    25681 tccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
    25741 agaacagctt tttcacaacc tctccactaa acggtgttca atcagctgac cctcggtatt
    25801 cgctcaaaaa acaacaaaat atgaggaact attttcccgt ttgtttctct aatactcagg
    25861 tcaaaacgct gatttcacaa cctcttttct aacttctcaa tcctcttcct ttattgatca
    25921 aataccaagt aacggcgtac aaaacaacga tgaataacac aagtacgatc atcgatgttg
    25981 ctactggcac atcgatcgtt ccaaggaatc cgtaacggaa accggagatc atataaacga
    26041 tcggattgac ttttgaaaca gcttgccaaa agggcggtaa catagagatg gcatagaaaa
    26101 cgccacctag ataagttaac ggctgcaaga caaatgtagg cacgatcgat acatcatcat
    26161 aagactgagc aaaaatcccg ttgagcagtc ctgctaatga aaacaagatt gccgtcatca
    26221 ataatgtaat gatgaccatg aaccatgaat acacatgaag tggtacaaag aacaaggaaa
    26281 tgatcgttac gagagagccg acgagaatac tgcgacccac accaccaatc acaaagcccc
    26341 aaataatcac atgcgtagga acaggtgcta ccaagatttc ttcgatattt ttctgaaatt
    26401 tttgagagaa gaaggacgaa gaaacattgg catacgaact agtgatagca gacatcataa
    26461 tcaaaccagg aacgatgaat tccatatatg aaaaaccacc catgtcaccg atccgcccac
    26521 cgatcatttt tccgaaaata acaaaataca aggatgtcgt gatcactggc ggaaccagtg
    26581 tttggaccca tatacgcaaa tagcggttcg tttccttgat agctaaactt tttaatgcag
    26641 taaaataaag attaaacatt tttctcctcc gtatgattat tttcttctgt gattttcaag
    26701 aacagttctt ctaaacgatt cgacttattc ctcatagaaa gaactttgat tccttgtctt
    26761 gtaagctgat cgaagattcc gttcacccct tgatttcgtt caacttcgac agcgattgtc
    26821 tgctcatctt caaatgtaca agcatatcct tcaatcacag gtttggtatc atatggcgct
    26881 aaatcaaaga taaatgtttc aaattgcagt tttgacagaa gctctttcat acttgtattc
    26941 tcgatcagtt cacccgattg gatgattccg atgttgcgac aaagcatttc agcttcttct
    27001 agataatgcg tcgtcaaaat gatcgttgta ccattttcgt tcaattctcg tagaaactcc
    27061 cacatctcgc gtctcaactc gatgtcaact cctgctgttg gttcatccaa gatcagcaaa
    27121 cgtggttcat gcatcaatgc cctagcaatc atcagtcttc gcttcattcc cccggaaagc
    27181 atacgtgcac ggacatttct cttttcccaa agattggact gcttcaaata tttttcgctg
    27241 cgtttcatcg cttctttgcg agagacaccg tagtagcctg cttgattcac gacgatttgc
    27301 tggaccgttt caaaagggtt aaaattgaac tcttgtggaa ccaatccaat ctgttgcttt
    27361 gctcgaacta gatccttgtc cagatcataa ccgaagacat tcacttttcc agatgtttta
    27421 ttgactaaag aagtaataat cccgatcgtt gtagacttcc cagctccatt tggccctaat
    27481 agcgcataga aatctccttc tttcaccgaa agatcgattc cccgcaatgc ttcgacccca
    27541 cttccataga tctttttcaa attatttatt tcaagcgcat ttgccattta tttcctatct
    27601 ccttatagac atgattctta attgtatcat ggaatacagc agatgaaaaa acaacttggc
    27661 ttccacacaa aaacacacct gctaacaaag aggagatgtg ttttctagtt catgatcatc
    27721 ttcgatagaa taactatcta aacaactctg gaacttttaa aatcataaaa gtaccgacag
    27781 caactactac gatgacatat agaagatcct tataactgag gttcttgtct tttttattca
    27841 tgttaagctt tcctccgtcc ttttatcgaa agcttttttc ttttatttta accgaaataa
    27901 ataaaatgga aatagttatt ttcaatttct gttttcgctg tttgttttac ggagaacttt
    27961 gccatggaac gtgcgtctcg tcgctgatgc taagtttttt cgataaaagc tgctagaagg
    28021 aagacagcgt ggtttatttt gtatcgtctt ttgctaaatc ttccaagatc atctggacag
    28081 cagactcgtt cccattgaat tctgccactt ttttggcatc aatgtacttc ttttgataat
    28141 cgtctttttg gacccacgca tcatgcttcg tttgataaag ttaatcaaac ggataccact
    28201 gacgctgttc atcgaacaac aaactttctt tttgggcctg ttcaactatg gatttaggat
    28261 aattcaaaac tttcagcaag gcaatcgcat ttcgggtcct tgaaggtcct tcttttaatt
    28321 tgaaatcaaa actgattcct tttccttctg ttacttgttc ttcaaagtgg acattctcac
    28381 aataattctt taaaatctct gtcaattcga tatcatgtgt ggcgacaaat gctaaagatg
    28441 gatactccgc aagccaccga acgactgaag cggaagaagc aatccgttcg atcgtatttg
    28501 ttccttttaa aatctcatct acgaagcagt agcagcgttc tttggaagcc acttggtcca
    28561 gcaaacgttt gatcgatttg atttctgaaa caaaataact gtcgccttca aataaatcat
    28621 cttcgattgc catggaagtc aacacatgtc caggttgcag ggtaaactgt tctgcaatcg
    28681 ctgtttggat cgtctgtgct agaatacagc tgatggctat acttttgaca tacgtagatt
    28741 ttcctgatgc attggaaccc gtgactaatg tattcttctg ccagttgact ggattaacta
    28801 ccgcttcttt taacaatgga tgatagatat ctttcgctgt cacaccgccc tcagtaaact
    28861 ctggtcggca agtgatcggc atataggtgc gataattcaa aacggctgct gcaacttcca
    28921 attctcccag caattcccac agcttgatgg cttcagttga atgcttttct aatttagtga
    28981 gaacgaaatg ataggagata aatggcagca tgaacatgat gttgacatat tcaaaaatca
    29041 attctgcttc actcccgctc ttcattcgaa atgaaaaacc taatttaggg atgtctctta
    29101 atggtttagt ttgctgtttc agctcttttt gaagtggtgt cgtcattttt gctaactgat
    29161 tggcggctga aatcgttgaa accaaataac tcatgctatt cagctctgtt tctagtgttt
    29221 gtttcttcac tagataatag accgtattga atactaagcc accgattgct agatagattc
    29281 ctagtacttg ccctaaaaga agcaaaccta cacccaccag cggaagcaag ccaagaaaaa
    29341 taaataaacc tacgcgtcca atctttttac tttttccatc cgctagatat tgttttgcaa
    29401 aattatgatc tttttttcct aaacgagcga attgatattg gattctttct ctcagttgag
    29461 gattttcctg ataaaaagca attagttttt ctaactgata atcttctcca aaatcaaagc
    29521 tacgtaaacg ctgatacaac gcttctgaac ctacactaga ataggtactg ttgatccctt
    29581 caaatacttc gaacatatcc aagtcatacc aagtaagatc gtcgatttca ctatcccatg
    29641 aacggaattt tttctccgtg agccacgcat ccttcaaact ttcttcttta tcaaatctcg
    29701 gttgataagg aatttttccc caattactac gaactgtttc ctttactttc aaacgtgaaa
    29761 aaatgtctaa aacaactaat aaaataacaa ctgcaataat aattaaaacg ataaattctc
    29821 tttggcccat atccctctcc gttccttgat ttgttagttt tagtatagca ctgttgcgct
    29881 atttgaaaag ggggtacaaa aataactgtc ttcgttacct aattcgtatc aatcacacca
    29941 aaataaaaac accttccaaa aaagaagatg tctttaaaac gagatacaat tttttgtcat
    30001 tcacttcagg taaattagag ccaattaaac cctccgcaac ttgacggaga tggagaagat
    30061 gcccccgtct aatctagcgg tcatctctcc tcccattcct tccaccaatt tttttgacag
    30121 gtaaagcccg attccgctag attccgtatt tgtgcggctg gtattttcgg tataaaaacg
    30181 ctggaagact ttttcaacag aggtttgcgc tcctggtttg ataggattgg ccactgttaa
    30241 tcgaatgaat gaatcctctt ttgaaaatgt cacctttgct tgtccatctg cataacgcaa
    30301 taaattctgt atgatatttt gcagcactcg cagcaacatg agcggatctg ctaatacagt
    30361 tgtatttatc gagtgttcag cgaacgctac ctcgatattt ttctcagaaa attgttcata
    30421 aaaagagaaa aatacttctt ccacctcttt agaaaaagaa agcgtatgga gatccatttc
    30481 tttttgcttc gtctctattc gagcaagatc ataaaactga tccgtcatac tgagtaatct
    30541 tgcaacagat tgtttgatga tcgttaaata cttctcccgt ttctccgtat cctctacctg
    30601 ttccagtaat tgtacataac cgttaatagc agtcaaagga gttctgagat catgagaaag
    30661 gccgacgatc gatagtctga tgttttcttc catttcttga aatgcttgtc ctttttgttc
    30721 attttcatcc acccatgtat tcagtgcatc tactaggtcc attagattct tttctcgaaa
    30781 ttcgactgaa agacgaccac catattcttg tcgttcagaa agagtggcga ttttcttagt
    30841 taatctcttg atttcccttt gcaggaagaa aataaaactt cccataaaga taacaacgag
    30901 aagcaacagc cacttaatca aatctaaacc ccactcccca caccgtatga atatacacag
    30961 catgtgcctt tgctagtttc cctcgaagat tggaaatatg catattcact gttttctcac
    31021 tatcaaaata tggttcttgc caaactgttt cataaagatt tgctcgcgaa aatacttttt
    31081 tcggatgttc taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa tggacagcca
    31141 caccattcac atttacatcc ctcgactctt tgtccagtaa gatttccttg taatagatgc
    31201 gttgcgacag atcttttact tggacagaag tctgatgacg aagttggatg ccgattcgta
    31261 acaacagttc ttcgatatca aatggtttcg tcacatagtc atccgctcct gctgccaaca
    31321 aggaaacttt atctctttga tcgctttttg ctgaaagaac gatgatcgga acattcgatg
    31381 tctgtcggat ttctgctaac aatgcttcac ctgaaagccc tggaagcatg agatctagaa
    31441 ggatcaaatc gacaggatat gtgcttaaca ataattttcc ttccgtacct gaataagcat
    31501 caagaagttt gtatctctgt tcaagaacct cctccagtaa agaatgaaca gcttcatcgt
    31561 cttcgataat caaaatagtt tccagcagga acacctactt aatgtcagat ttttggaaaa
    31621 taaacattcc tagagctgat gataccacga ttgttactag actgaccaga atcattttcg
    31681 gtgcttgcga ataagttgct tgttgcgcaa agtccgtata catgagccac gtttccgtaa
    31741 accactccgt tagaaattcc aagcctttga tttttgcgaa aacaccggga acgaaggccg
    31801 ttcccatgat ataaagaaaa gaaagaagca aactgacact ggtacttcta gtgatgaatg
    31861 tcaaagccac tggaacagat aatgtcgcta atatcagcag aagcaataca ggaaatactt
    31921 ttagaacata atttccatag tttttgattc cctcaacttc accaaatccg aaagcaagtg
    31981 tgtaagcaat catggctagc cccgtaatca aaaccacgcc aagtgttgtg atcaaaagcg
    32041 taacgagaag tttcgacaca taataagtca ttcgattccg tcctaaagat aacgtattgc
    32101 gaatcgtacc gttttgaaat tcttccccaa tataaaagca cgcaaatgct gcgaaagcca
    32161 gaagaatcca tgcagccatt ttttccacca ttaaaatccc tgttgcaccg ttgatgactg
    32221 tatccgttgc ttggtttaat tcattgccgt attttgtatg catataccat tcgttccaag
    32281 aataaaaaag cggaagtacg accatcagtc ctagtgagac ccacatttta cggctcttcc
    32341 atacttttat tttttcagca gttaatagat taaacatgtg gattgcctcc agttaattgt
    32401 aagaaataat cttccagttt ttgcccaact aggtggatac catccacagg aacttttgcc
    32461 tctaccaatg cttgattgat ggctgctact tggtcaattc cttcaaaaag ctggataaca
    32521 cggctagatt ggacaaaata atccctataa ccaagagagt cgagaaccgt tactgcttgt
    32581 tccgtcgccg aagtgtcaat ttttataaat tgacgagatt cttgtgccaa ttcttctttc
    32641 gataattctt tgatcaagtg tccttcatgc aaaataccgt agtgagtggc gatctgtgac
    32701 aattcatcta gcaagtggct agaaagcaag acggtgatgc cccgttcttt taccaaacgt
    32761 tggatgattt ctcgcatttc tgccatccct gctggatcca tcccattcgt cggttcatcc
    32821 aaaatcaaaa attctggatt cgtgatcagt gcatttgcaa tagctaaacg ctggcgcata
    32881 cctaaagaga aattctttgc tttctttttc cctgtatttt ccaatcgcat cattttcagc
    32941 aggtcttcga tttctctatc cgacacaccg ccgttcgctg cttggatacg taggttatct
    33001 cttgcagtta attctggata aagagcaggg gtttcaatcg attgacccat acgtcgtctt
    33061 gctgcctgca aatccgtcgt tccaaataat tcgatcgaac cttcatcaat cgagatcaaa
    33121 cccataatag ttctcataaa ggtagactta cccgctccat tctccccaat caaaccatag
    33181 atcattccac gtttgatttc gatcgatact ttatctaatg ctttggcagc accgtatttt
    33241 ttggttatac cagttgcttt caagaccgtt tcatttccaa aatccatact tatccttctt
    33301 tcttattgat aagtgaagta tagttgacgg gtataaagaa agcagccaga aatgtataaa
    33361 gaaagtgtaa attttccaat tgaatttcaa gaaaaatcag actgtctcgc agacgtggtt
    33421 gagttgtctg ccaatcaaag agcgcaccaa acagtgctaa tccaagtgga ctggccacca
    33481 tggtaatcgt tgttatcgtt gacatcagac gtccttgtat atgcgttgga acttctcgct
    33541 gaagccagac catataaaaa gcaaaagaaa acattaatcc ttaaaaacgg acttatgaaa
    33601 aataatacat gccgtttggg atttacaatt agctaccaaa taagaggtta tgacaaaaga
    33661 cttttcacaa tcccttcttc cgaataaacg gtgttctcct gccaactcct cggtcacaag
    33721 tcacaatatt tatcaaacat gagaagcaat ttttgtaaat tccttcttat ttcttgaagc
    33781 tgaccacttc tgtcacaacc tcagaagcgg ataaataata ttgtttgatg atactttatc
    33841 tttttcccgt ttgtttatag atcgaatgat attatagacc aagaatccta cctattaaca
    33901 tagctaaaaa cacaaaaaag gcactttcca aattgtggaa agtgccagaa aagttaggat
    33961 taaggtaact gcgctcagca ttgcttcgcc cagtacgatt ctcgtaactc gtgaactcga
    34021 acgataatcg caattaacgt tttgagaact gtgaagcttt acgggctttc ttaagacctg
    34081 gttaaacaaa cttttgtttt ataatgtttt acagagaaag aaatcgtgta aaatcagcat
    34141 ttaatgattc atataattct acttagttaa ataaagttat atcctgtcat tacctcaaat
    34201 cattaccaca acttggcgag ttggctgatt gaagaatatt ctgtgccaaa taaaaaaaat
    34261 gatgccaaaa ataagtacac tactcaatac ttattttcaa catcattaat cctaaaatag
    34321 cttcgctttt acccgttact atctaccctt tcggaagggg tatttcatct gactaaagaa
    34381 tagcatccaa gataccaata gtcaagtaat taatttacca tactccatta caattttttc
    34441 aaaaaagtgg aaaacttcta caagttcatg attcttttcg tacattttac cattaacttt
    34501 tatgcgatca agtaaatcag atagagcctc aaagtttgtt gttttcaact tttgtgtttg
    34561 aacatatttt tcgtgaagat atatagtagc cacaatatca ttcattttca tattggtgag
    34621 tgctctggcg attagttcag aatcaagacc cgcattggtt gcaaactgtg ttaattgaat
    34681 aacaggcctt cttttcttca agttgctgtc agctctacca aattgataag gttcaacaat
    34741 attataaata agaggtctac tatgtgcaga ggcatttctg acattcgtaa catattttaa
    34801 taatttttga gctgttttta atcctagata tccaaaatgt tcttcttcaa aatagaaggt
    34861 gataaatctc tctaaatttc ctagggtcat aacttctaat aaagcccaaa ttgaaatctt
    34921 atcatgatga tgattataaa aatcaaaatc atatccgaac ttccctttca ctttatctag
    34981 aatcttttca gaagcttgtg tatattcaga caagatttct tcgtttgttt tagtattacc
    35041 tttttttctt tgactatcaa taaatttatt ttgcatatac atatcgtaat cttcaacaat
    35101 tttatatcca tcttcggtta atgaattagt gattgaactt attatcaaag ttttcaaaga
    35161 atgttcaagt tcaaaaatca ttctactcaa aatcattctt aaatacatat caatctttgc
    35221 taaatcagct aattttacaa atgataaatc tatatacttt ccatttatat ctttttcaaa
    35281 attcttacgg tatgcggtta ccttaaaata atacgttcga tataataaaa tatcctgaac
    35341 aatactttca tccgattcag aaatttctat tcctttaaat ctagcatatt taatttgatc
    35401 cgtaattgaa aaaatttcct tgtttttagc ttttttacaa agatctttaa tttcttctga
    35461 taattcttca gagacttgat taactctctc ttcttcttct aactgcaact ttaatttagc
    35521 caatttgtcg cttttaataa aaacacacct cctttatctc tttattttta tactatcttc
    35581 ccaacatctc cataaacttc cgcaattctt cttgcgcttc atctgttgtc ccgtgcaatt
    35641 cacctagcat ttcaaataat ttatctgtcg atttttctat ctcttgcttc acatctgcta
    35701 attcttgtgc aaggtgtggt aatggagtca cttcttcttc ctcaaacgtg tctacatatc
    35761 ttggaatgtt taggttataa tcattctctt taatttcgtc taaagttgct acatgtgcat
    35821 atttttcaac atcttcacgt ttttcatagg tttcaataat tttgtcaatg ttttctggtg
    35881 ataatttatt ctgatttttc cctttgacaa attcactaga agcatcaata aatagaatat
    35941 cttttgttct cctagattct cttcctttga ataccaacac agcagttgga atacttgtcc
    36001 cataaaatag atttgccggc aatccgataa cagtgtctaa caagttatta tcaatgatat
    36061 ttttccggat tctcccttca gaagctcctc ggaatagtac accatgaggc aatacaatcg
    36121 ccatcgttcc agttttatct aagtgataca ggccatgtag cacaaacgca tagtctgctt
    36181 tagaagcggg tgctacgcca taacctttaa accgtgtgtc tttttctcga tccacattct
    36241 ttatatccca cttagcagaa tatggcggat tagccactac agcatcaaat tttaatggaa
    36301 tttgcatacc atctttttct gcgaatggcc agtctgcatc aagggtatca ccacgtttca
    36361 aattcatatt tcgataatta ataccatgca tcatcagatt catacgagct aagttatagg
    36421 ttgtcgtatt caactcttgc ccatagaaat caacactgcc ttgcttattg ccatcgggta
    36481 gttcattttt cactgtcagc agcaacgagc ctgatcccat tgctggatca taaactcgaa
    36541 attgagtatc atccgctttc gcatctttgg ttacaatctt tgctagtact tggcttactt
    36601 catgtggggt ataaaattct ccaccttttt tccctgcatt ggcagcaaat tgaccaatta
    36661 agtattcata cacatcaccc aggatatcgt gaccagaatc atctttaaag gtaaaatcgt
    36721 tcaccatcaa aacaacatca ttcaaggctt ttgctcgttc attcgtattt gatcctaacc
    36781 gagtatctcc aagattaatg tccgaaaaaa cattggcaaa atcatcttcg gcaactggat
    36841 tccgtttcgc attcaaattg aacgaatcaa gcatatcctg aaagtcactc gctttgattt
    36901 ggtggttttc aatctttgat actaactgtt cccaagtata ttccggagca atcgcataac
    36961 cgattcctcg actgatttct tccaagtaat cttctttttc ttcagagtca gtgacttcgt
    37021 agtactcgtc taacccattt ttttctaaat actcgtcttg attttctgat aagtagcggt
    37081 agaacataaa tggtaaaata taatttttat actcacttgc atccattgtt ccacgtaatt
    37141 tattggccat tgcccataat tttgctgtaa tctcacttgc attactcatt aattttctct
    37201 ccttttagac aaacattttt tgtagcaatg tttttttcat ttcttttagt gaatccaact
    37261 cacgctgatg aagggtgatg gtggtgtcga gacttttaaa gaagtccgca attttttctt
    37321 gctcgttatt attttttgga atcatgagtt cagtttcaaa aaaatcagat gcagcaatat
    37381 ttaaaagccc atgattccta gctccctcag cagcatgctt agaaacctct ttataccaac
    37441 gatctgtatc ataatatgac gctaaaaaat ctgaatttat gtcgaccggt ctaaaacaaa
    37501 tatacaatgt tgataataca cccatgtcat acttatctag tcgcttaaca gcaccccaag
    37561 gatagccatt ggagtagctt ttattatagg caaactcacc tttcttcagc agataatatc
    37621 cgctaacatc cttactggca atttgcttat taaaaaaagt attctgatca actaatccaa
    37681 attgtgctga tatagtcagt ggaagtgttg attcaagctt tttgttcttt ctggtcaccc
    37741 tagtggcaac ttcccccaac ttacgctgtt cccaagcgtc agtaaatcca gcaaaacgaa
    37801 tttctggttt atcttcacct gttttaggaa acattttttt taaataagtt tgttttgttt
    37861 gctctaacag atcaagctca cgctgatgaa gggtgatggt cgtgtcaagg ctctcaaaaa
    37921 aggtagaaat ttgcttttgt tcttcaatac taggaaccat tactttaact gattttagcg
    37981 ttggaaattt caaattccat gtatcagatg ttaagccttg tgagtttctc ttgaacgttt
    38041 gaatcatgtc atatcgcttg aaatcatacg caaagaactt cgagtcaata tctttttttg
    38101 gaatgataac tgtgtatgca gggcttagaa tgccattata aggggaatat ccgcttgcac
    38161 cttgccacat tctcattgag ttgtatgcaa tatcaccaac ttcaactttc ttgtaatttg
    38221 acttgtcatc actggaatta tcttttctat caagttcgct tgcctttaca actcctgaat
    38281 taatagtgac cgagataagc tctccttcgc cactacgttc tgaccgttca gagaacacct
    38341 ccccaacctt acgctcttcc caatctccct cgtatccgtc aaatcgaatt tcaggttctt
    38401 ttgttatttc attgctcatt ttaactctcc ttcgatcttc gttatctcct tatcaaaatc
    38461 agaaacgata tgctgatgtt tattgaactc cttgtactca tcaaccgctt ttctcttagc
    38521 tgctttactg ctaatttttc cgtttccatc aagaatttga tagcgattaa atgttagaaa
    38581 ttcatctatg cttttggcaa aatcttccat acctaaaagt gtttcatctt ccaataatcg
    38641 ctcaacataa tcaaaataag aagatacgtt ccgttcaaga ctgcgaattt gtttttctga
    38701 taaataattt ttagcaactg atacatctga ctgtaggatt cttccatctg gagagttttt
    38761 ccaagtcgtc agtcccatgt tctcttttgt tttatctgca ccattaaaaa caatctccgc
    38821 agctgttttt ccagtaatag catagtgaaa tttattttgt acagtggcat aaaactgctt
    38881 cgtaatttca gagtttttgt cataatcata agagatttct gcaaatacat cagtaatttg
    38941 ttgccaaatt cttcgttcac tggcacgaat tgagcgaacc gtttctaata actctcggaa
    39001 gtaatccttt ccaaaagcat tctcaccttg tttcattcgc tctacgtcaa ttttgaagcc
    39061 cttttgaata tagtctttca gaatatctgt tgcccagatt cgaaattttg ttgctttttg
    39121 agaattaact cggtaaccaa tagaaataat cgcatcgaga ttataatatt tgaccttatt
    39181 tgtttgtgtt tttccatcta ttgcgccatg ttgagtggta ttttccaaaa tggaaacaac
    39241 cacttcttca tctaattcac cagactcaaa tatatttttt aaatgcttgc taattgctgg
    39301 taccccaaca tcaaaaagtt gtgaaatcgt cttttgcgtc gcccaaattg tctcttctcg
    39361 aataagcact tcgactttat cactatcttc ataaattaaa aactgaattt cattcaatag
    39421 aacttactcc cctttcttag tctcgtccgc catctgatag aaagctttcc gaaattcaat
    39481 tcgatactta acccatgaaa gattcgccac ttccgctgct gcgatttctt tataatctgt
    39541 tcgtgcatcg ttcatcattg ctgttagttc accttgtttg tccatatctt cttgaccaac
    39601 tcgatgccgt gaaattaatt tggctaaatc ttttggcttc acactattat ccaatcccca
    39661 tgtgcgaaca aattctgtat atagtttgat attgctatct ttttgagatt gttccatcgc
    39721 ttgattcatt tcttcaacat ctctaggagc cggatactta tcaaagatga attccttcgt
    39781 aaagatcttg gaaacaaaat tgcgaacttt cgtaatctcc ttatcgctat ccgattttgc
    39841 aatttcaaca tcgatctcat tttttgtcag ctcagcttga tccattttat cttcatgaac
    39901 ctcatctgcc attcgtgcga tcaattcaat cagataatca taattgatcg tcacatcgtg
    39961 aatatgcgtc atctctaaat tgacttgcga tatatcgata ttttcgattt gggctcggcg
    40021 ttcacgcaac tcgttagcaa gtaccgttgt cagcatgacc tcttgatcct ctgtaattcc
    40081 taagcggtca tagaacagtt ccggttcatc ataaacagaa acaggatttt tttcatcgtc
    40141 ctccgtgaat tgcttcagtt gatttagtaa tcgattgtac tcctgtaatc cttcaaatac
    40201 ttcctcttgc gctttttcac ttggaggtaa ttgaataaaa ttatctgtta gttcagctaa
    40261 tttctgaatc acttctttgg tttctgattc gattttacta aatgatttcg ataaaattcc
    40321 cgactcttca ttgtcttttt ttaattcatc tagcgatagt tgctctgctg ctgaatctcg
    40381 atttgaataa atagcaaaag acttattcat ttcgtattca ttttggatgg gccaacgata
    40441 attaacaata tttccttgtg gctttgcatc cctatcatgg attctattcg tacgtgaata
    40501 tgcttgaatt agattgccac cttttaacgt acgatcaatg tacaatgtat taagctccgg
    40561 tgcatcaaaa cctgttaata gttgatccac gacaatgact agatccaaat aatttccatc
    40621 gtcagctgtt ttgttcaaac gtctagctaa atcttctgta tatgatttaa ctgtcgtcat
    40681 atcaaaagca gtaccaaaca atctattata agattgaatt gctcggtgaa gattttcatt
    40741 tgtttttagc tgatgactac tatttgatgt atccatcgaa aaactaatgg caacttttat
    40801 ctgatcctca attgaccgtt tattattttc ttccataaat ttatcaaaat attccattgc
    40861 tcgaggagta ctagcacgat ttccccctac atgtactgta aataacgcat tgtatttccg
    40921 attattagag cgttctttcc agttatcaaa aatatcttca acaacgagtt ctacatgctc
    40981 gggactatga tcatacacac tgccacgaag attgtcgtca atatcttctt ctgtaggatc
    41041 tgctggtgct tcaatcgtct ccttaaactc cactttgaat cccaaaacgt ttttatcagc
    41101 gatagcttct ttaatcgtat aagcatgtaa taagtcacca aaaatttctc gcgtttctgg
    41161 aaacttaggt gtacctgtat aaccaaccca agcagagtta ggcaaggctt ttcgaataga
    41221 ttctagcatc ccttcatttt tagtcccatc acctgttgaa cgatgtgctt catcaacaat
    41281 aaataataca ttctcagtta atggttgaaa gctgtctctt gttacatatc gagacatttt
    41341 ttgaatactt gttactatga tgtttttatc actttttttg gtaagtttac ggtgcaagtc
    41401 agaaatattg gcagtatcac ttacaacacc agttttccct tcaaatccag cgattggatc
    41461 atatgctcta taggcatctg ctgtctggtt tgtcaatgca attcggtcta ccaagaaaat
    41521 aaccttgtct acatttgata agcgactcgc taaccatgcc gttttaaaac ttgtaatcgt
    41581 ttttcctgaa cctgtcgtat gccaaatata gcctagcttg ccctcgtcat gcttaaaatc
    41641 aaatttccta actttatcaa gtacccgttt tgttgcatag acttgatacg gacgcatgac
    41701 tttgatactt tctttgttct ttgtaccatc caacaccata tatcgagtag ataaatcatg
    41761 ggccatggga atagacaata ctttatctgc aaacagtttc catgaacgta ctggatgagc
    41821 tgtttcttca tcttgccaat tgaaagcaaa tgcacgattg aaattttgta atgtagtatt
    41881 tgccatgtaa cgaatatcaa acggggtcat cgcaatgagt atctgtaagg tagaaaaaat
    41941 cccactaaat tgtttctcag caatatattg ttccatttga tttaaagctt ctgtcgcatt
    42001 atgtagcgcc tttttcaact caatttgaat aatcggtaac ccattaatca aaagcgtaat
    42061 atcaaaccga cgattgggct taccatcaac aacttttgga cgttgaattt gattaacgac
    42121 ttgatagact gtatttccgc cgccaacttg ggcttgatca aaaacggtca aaaaaacatg
    42181 ctttccgtta tcaagatcaa cttcaatttc tgatacacca tttacaccat ataaaaattg
    42241 tccagcttga taaggcgtat taatattggt aataattttt ttcacttgat tgaactctgt
    42301 tgcagataac ggttcatcta gccgagcttg attattttgt tctagaattt ttttgaagtt
    42361 gttccataat tgttctgttg ttttaatttc agctttatat tcccattgtt ttacgccacc
    42421 gattcttgtt agataatcca caacttcttg ctcgaacctt aattcagatt gactttttat
    42481 accgaattgc tttgtcataa tctattcctc caaacttttt tctaacatag aatttgtaaa
    42541 ttgctctaac aagcgagtat atatacttaa cttactttgt aatttcaatg attcagtgta
    42601 aatcccccct atttttcttt gttcttctat aagaggtagc ggaataacaa gttgttccag
    42661 agactgtttt gttaacctta aaactggacc tgttccttga agacctcgat ctttttgacg
    42721 ttgaatatct ttatgattgt taaataagta aagaaaatag cgcttgtcta gcaaatcact
    42781 tttaaactct acttttgtaa aatttagaga cagaacttta ccaacattct gtccacttac
    42841 cattgttgcc cgttgaagtg aattactaat aacaacatcg cgtttatcta aagatacttc
    42901 ttgatcaaat aaatagttta ctctttcctc ttgagtcgct tcattataat acttatgatc
    42961 ttcttcaaat gaagcttgat cgtaataatc aatttcttga ttgccaaact gtttttcagc
    43021 tcttgattga ttaattcctt gaacaaaggt tacaaactca gaaagctttc tcatttccat
    43081 atatacttcc tcctaaaata caattcaggt ctcatttaaa cgatttatcg aaataatcat
    43141 atatttcttt ttcgtttctg cgtttttata ataaacctta tacagtaatt cgtcaatgga
    43201 aataatttta tattacaaaa aatccgcaaa aaatgcggat tcctttaaat atttaatctt
    43261 tattctagtg tagtacaagc ctatacccta acgttacata tctcattcat tattatacca
    43321 gtatttcttc atgacacata agggtgtaac ataataattt taaacgaaat gactacaagt
    43381 agtcattgaa gtaagtcttc ataagatacc tgtaggatat ccctaattgc tctcaattga
    43441 tctaacttaa tgtgttgccg gccaccttca attttaacca atgtttccct agttatagca
    43501 attttatgaa gctgtaggtc tctaatcagc tcggtttgac caattccttt ttctaatcgg
    43561 attcgtctaa tattgctacc gattacattt tctttatcaa taattttttc ctctttcaag
    43621 aatagcacac cttttggact aaaattagtc ctttttctta ttaatcttaa agattcggta
    43681 tgctacaatg ggactagtat tagtccacat tcaattttaa ggaggaattt ttttgaagaa
    43741 atttgcaatc attctaacct gcgctttact catcggaact ataagcgggt gtaccacttc
    43801 tgaaacaagt tctacaagta cggaaactag tacaacaacc tcagaaaaga attacccaat
    43861 acattttttt ccggttccag atggatttga agcttattat catgataaaa aactagatgt
    43921 ccctttatca gaaactgaat ctactgaaaa gattttgcca attgaaattg aaagaaatca
    43981 agacgatata aaactaaaag ctgatcttcc cttactgaac agcacacaaa ttgatagaca
    44041 tgaaaatatt aaagttaata ttgaaaaagg agcgttagca aaactttata ctgaaaaagt
    44101 tgaacaattt tttaagtctg gtgccaataa agacttttca aaaataagcg attattcgga
    44161 gaactttttt aatgaaaccc aagatgaaat catgaactca acttttatgg ctgaagatat
    44221 gtacaatatg acattaaaaa aaataaaagc ttacgaccat ccgttaaatc tgacactaaa
    44281 taatggactg ctttcttttg tattagcagg ttacgttgac tatgaatatt caccagatta
    44341 tttggagaaa cctcttcaac acgagaacaa tgatattaat tttagatttg tctacgagtc
    44401 aaaaagtaaa acatggttag ttgatcaatt aagcacgata aacacaagct tccatgaatt
    44461 acctaaacct gaaaatgaag ttgagatggt cattaaaatc ttctaaaaaa gaagcgttga
    44521 aggagaaata ttcctttcaa cgctcttttt tatatgctta gaaacataaa taaattgtat
    44581 actttctttt tagcccctat tacttttcac gaaaaatatc tttttttcga cgctagcgtt
    44641 tctctacttc taatactgta cacagttttt gtattattga aaaattactc attatttagc
    44701 attaatccac atcgttttat caatcgacct tcatactaaa ctactttaaa gtcatcttcc
    44761 ttctcgtttt tcattaaatc agatacataa gcccatgtac ccgttcgttg taaataaagt
    44821 tcttcttgta acaactccca ttttctctta gaaatcataa tgacgccatc gttcaatcca
    44881 tttttagaat ccctagtaat ttctatttca gaatttgaat gaactacttc ttgcaacact
    44941 tggtgttagt atcaaatctt agacagcttt tcgtagagac aagaataaat taaacttatc
    45001 tacgagagga tgaattttta tgacccgata tgaagaaaat tttaaacaaa tgattgttga
    45061 actgaatcaa actggacgtt ctgttcgagg gttagcgaaa gaatatggct tatctgaagc
    45121 aacgatttac aaatggaaga atttatattt acctgatcag tccacaggac tgactggaaa
    45181 agaagtagct gaactgagaa aagaaaatgc tcgtttaaat gaggaacttg aaatcttaaa
    45241 aaaagccgca gccatattct ctcggaaaac ctaaattcgc ttgttcaatt tattgaaaaa
    45301 tggtgtaagg attacactgt ttctttgttg tgtcggttat tagaaatccc tagaagtgtc
    45361 tattattttt ataagaataa accgttgaca gctacagaaa tcagaaataa tacgttgaaa
    45421 aagaagattt caacaatttt ttttacgaat aaacaacgct atggtgccac aaagatccat
    45481 caagttttat taaaagaagg gatttcagta tctcttaaac atgtccaaaa gctaatgaaa
    45541 caattaaatt taaggtcgat tgtagttaaa aaatatagac ctcaaaggtc taataaaccg
    45601 atcatttcaa aagagaatct cttaaatcag gacttttcta ctgaaacgat ctgtgagaaa
    45661 tgggcagctg acattacgta cattcctact aagaaaaatg gttggtgtta cttatcttca
    45721 atcatggatt tacacacgaa aaaaattatt agttatacat tttcaaaacg aatgactgtg
    45781 gattgtgtca ttcaaacatt gaataaagca aaaatacatt atcacattcc agaaggaatg
    45841 attctacaca ctgacttggg cagccaatac acagcaagag aagtggaaca atggcttaaa
    45901 accaacaaaa taaggcattc ttatagtaga aaaggaacac cttatgataa tgctggaatc
    45961 gaatctttcc atgcctcatt gaaaaaagaa gaagtctaca cgactagcta ctcagatttt
    46021 gaagaagcaa atcgagcgct atttagctac attgaaggat tttataaccg aaatcgaatc
    46081 catagctcga ttcactatct aaccccacag gaatttgaag aattagcaaa agaaaaaatg
    46141 gcttaaccgt ctctactaaa atgtgtccaa gatattgact caaatccaac tttacctata
    46201 ttttctttga agtttgttgg agtaatagta tccaaaatga acacctctct tctctatacc
    46261 tctattatga agcgcccatc aaataaagca agcgttgagg aataattcta tcaacacttg
    46321 ctttattaag ctttcatttt gtagtttgac taaaaccaat aatcttattt ctaaactctc
    46381 gaaaaacttc ttgtggctga taatagtctg catctatttc aaatgtttct gagaataatt
    46441 cattgaattt ttctactgaa ataatgattt taccattctt ctctcgactg ttttctatta
    46501 tttctgcttc taattcaaat aaatctagtg acgaattaaa atcataaatc ctgtcatatt
    46561 gaacaaaaaa atcaagaaaa agttgctcaa actctttctt atttatcact agtgtttcaa
    46621 gcagatcaac tttattttct tcagtcattc ttccaatttc ctcactttcg ttttcaaaaa
    46681 tcacaaaaat gatattaact taaaagccac taacaaaata agacttacaa attaaagggt
    46741 aatccaacaa aataaccatt cgctctacgt actacgattt ggtagtcctg cctttcaatc
    46801 ggtaattcat aatagtaatt tactgtttct gatttaccac tttcaatata ctcaggatta
    46861 tccaatatca tagcatactc ataaagctct tcaccatcct tattttcaat cgaccattgt
    46921 tgcggacgta tcggattttc tgtatcattt ttcattgtat aggtcacttg taatacacga
    46981 tcatgctgtg caaattcatt tcttttttcg gtcagttcaa tatttttaaa tgttagttca
    47041 accccatctg cctgataagt ttcacctatt tttaaatctt ttgttacaat ttttattggc
    47101 ttttcttctg gaaaatacct ggctttaatt gttagataac ttccaaaaag aatcaatcct
    47161 agtagcacaa aaaaaattcc tttaacgagc cactgaaacg ggaagtaaac tttaaacatc
    47221 ttttttctcc tccgttttgt atttggtttt tagagaacac gataactttt gatcaatacc
    47281 atccaacttt ttcattatac ttgattctag ttctgaaatt gtttgttcaa gtttaatgct
    47341 ttcaggatca ctaaattttt tatttgattg actagccaac attggtaaat ttgaaaccat
    47401 cacacggaac atatttgctt tcgttccaag agttccttta ttcttctcat aaaagctgtc
    47461 aaacaatttt tttgtttcct ttgaacaata tactttaata tacggatcag acattctttt
    47521 ccctctccct gtttacttaa aaatccatat catattgatt ttgttgtttt tgataatcaa
    47581 ttcctcttgc tgtttcttca tactctctcc gagctttttc aatcgtacca tcatcaattg
    47641 cacgattaaa taaataaaga acacgttttg tttcttgaat ataacgcttc ttaaaattac
    47701 gttttaaagc gggttcagta tcttgaatgt taaattggtc ataatcagtt gataaactct
    47761 ctgcgatatc ataaacaact tttttataca ccaaatttac acatttcttc ttatatttta
    47821 aaggttcctc ttccactgca aatccaaaga attggttttt attctcacca aaaacatcca
    47881 ataaattttc tattctgtcc tctatttcaa atttatattt atcataaaat tcttcataat
    47941 cttttgatga tctaagaaat ggtatattct cattatctaa ttcaaagcgt tgcgctcgtt
    48001 cttgccaatt aaatctacta tccgctctac catttaacga tttaccaaga tatcgaatag
    48061 caatttcagt gagtacctct tcagattgaa tttgctccgc ttttttattt tctgtgaaca
    48121 aatcatcaag ataattcata tcatagtttt gccctaaacg ctttccgcca atctttaaga
    48181 ttaacccatc ttcagaatct aagagtttgt acccaatacg ctgatttttg gcaaaccggt
    48241 aagtctcaat agaatggttt ttcttcaatt ccgcatgaaa atcatcataa tttttcgcat
    48301 actgagcaac ttcagaaaca gctagtttta ttttttctcg atttgaaatc ttattttcag
    48361 ttctaaattc acgttctttc caattttcac gatctgcaac taaatgatta tacttataca
    48421 tatcaagtgg gttaattcca ttatcaataa gtatattatc attccaagcc tgcaaaactc
    48481 gaatatcatt ctttcgaata tccattttct ttcctgttcg ctgatcgttt ggcgaaatac
    48541 caaagtgatt gtgaacatgc cctttgtctg tgtgtgtgac aaccaaaatt gactggttag
    48601 gaaacatttt ttctgcccac ttaacaccca actcatgtgc tttttcagcg gaaatatctt
    48661 ctagtggatc aaagctttgt gtaaaatgcc aaagctttat tttcccttta tcaccaaaaa
    48721 tttcattggt tcgtttaaat tcctcaatag catttaaatc attcgatacg ccaattcctg
    48781 tcacgagttc agaatcttct tgtttattta acatatatga aattgtatta tgaatactcc
    48841 tactttttga agcaattttt ataatcgagc ccataactta ttcaactctt tttccaagcg
    48901 attcaatgga tcacttattg attttatttg tatcattaag tcattttttt cagcatatag
    48961 ccgctttaat cgctcttgct tagttgtaaa agataagtaa acactctgat gttcttcttt
    49021 ttgtatctcg gtatcttttt tatttaactg aacacgcaaa taatttgctg ttttcactaa
    49081 ttgattcaaa tttcttccta ttgctagtaa atgaaaatta atttctttat attgtcgatc
    49141 ggtatatttt agacttttcc ctgcgttgtc tactgcgatt ttcttcacgt acattggaac
    49201 agataaacca aaaatgtctg ctgttttttc tagctcttgg tactgataat cgtctactcg
    49261 aaactttatc ggcctatttt gtcgtcgact atcttcatta cgtttatatc gctttctcct
    49321 ttcttctaat ggtagtttac tgacatcaat tgccatgcgc acttctcctt tgcaatatta
    49381 tttttaagtt caaaagaagc aagcgagggg aaagggaacc cttccccgct tgtcgaggga
    49441 gtaaactccc tacgagcacc ctcatgctcc gcattttatc gagattagat agccgataaa
    49501 tcagctacct aacactttct tcttgcgcct cttctcgata gaaaattcga tacgctgtct
    49561 ctccttttct tctcaaaaat tgttggaatt tcgtttccat caattgatcg cttgcaagaa
    49621 attcgtgtac tagggtaaat tcgctattcg cgaaatttac cgccttttgc catttttctt
    49681 gagtaccttt ttgattaatt tcaaaagttt cttcaaactc ttttactgat gaaattcctg
    49741 ttttttcata gacatacttt cccagttcgg gataaagttt tctctccaac tcggcgagtt
    49801 cttttttcaa atctgcaatt gacttttgtt ttttccttgc catttttcat gctccttttt
    49861 gtatgtgact aagttcattc ataagctcat ttttcatcac taattcttct tgaatcatca
    49921 gttcaatata atttgtgacc gtgatttttt catttgtcgc tttctttact gagtcgcata
    49981 attcggcaag ttctaagaaa tcctgcgtac taatctgtag aattaattgc atgacaatca
    50041 cctctttatt ttttaaatag actatcaaac agcggatttg gtttatcaga aatatcctga
    50101 aacagtggat tattttcata agtaaatcgt tgacgtttct tctccttcac ttcttgttct
    50161 actatcactt tttcattagg tctttctttt cgttcctcga caatatttat tttttgcgtc
    50221 ttatctccct gacttgcttc agctcttgtt tcacgtactt ctaccgttct tggttgattt
    50281 gacgcactac cttgtacatt ttctcgtaca tctactgttc gatttccgct ttgactactt
    50341 gtagtattct gcaagttttc tcgtacatct atcgttctcg gttgatttga cgcactactt
    50401 tgtacatttt ctcgtacatc tactgttcga tttccatttt gactacttgt agtattctgc
    50461 aagttttctc gaatatctac cgttcttggt tgacttgtcc cactactttg tacattttct
    50521 cgtacatcta ctgttcgatt tccattttga ctacttgtag tattttgcaa gttttctcga
    50581 acatctaccg ttctcggttg gcttgtccca ctactttgta cattttctcg tacatctact
    50641 gttcgatttc cattttgact acttgtagta ttttgtaagt tttctcgaac atctactgag
    50701 cgcctatctt gactacttgt agaattttgt ggattttctt tgactgattt ttctaatccg
    50761 gtatttgaat ttttagcttc ttggattctt tctttagtca acgcttcttt ttcgtccata
    50821 ttagcgcctg tacgcccttc tacacgtttc cttaacattt cctcacgatt cattgcttca
    50881 ggcgtgtatt ttgcttcctg tcgcttctga ttaattaatt cttcagcaga cttagcttga
    50941 ccgtgcatag catttttacg ttcttcaata tcttgtttaa ctttttgctg aattgcactt
    51001 gcaggattaa tatttgattc agcattattt ttcattgctt cacgcatacg ttcagaacta
    51061 gacataattc tatcagcgtt ttcaacttta gcgccatctt ttctatccga aagacgtgtt
    51121 ggcatagaat cagcatattt tccagtttca tcttctttat ttttagctac tataggtttg
    51181 ctatttttat taatagcgga catggtacca tcatctaaac cttctttgaa tttattcttg
    51241 gtatcattag ccatatcacg catactctta aatggttttg ttgctctttc actagccatt
    51301 gtagctccat ccgaagctaa gcctgataat ctacgttcac gagcataccc aagcgttttc
    51361 cccgttttat tagctttttg agaaagtgat tgaccaaagt tgcgttcagg ttttcgttct
    51421 tctccttccg cttgatcgtt tccaccacta tttttcccac ctttagatcg gttcatacca
    51481 cctgttcctt tacgaaacag cattgcaccc atgccaaaag cagaagcaag ttgcccatag
    51541 ccttctttga gtccaatatc cacaccaaag taacgcatga ctgttccact gcctttgatt
    51601 aaaacaaaca cagcacagat ataagcaatt gtttttataa agatatttgt tgagatacct
    51661 tcaccagcat ttagataatt gacaaacatt gcaaacatag acaatccgaa cccttgaaat
    51721 ccgactgtca aataacactg taaaatatct gacaaaactt gttttgatcg ttgacctgtc
    51781 tctaagtcag tagcaaatac caaaactcca agtacacgtt taaatgctaa ctcgagtatt
    51841 gctgtaatta taatgaaagc actaaaaaca tacgctactg ctaaagcaat caatccaaat
    51901 gaaattcccc acaaattcgc ttgatagcga taatatcctg atttgatacc atcaacaaag
    51961 gttgacaaaa aattatctga aaatttagta gcaacaaatt cattatcaga attttcaact
    52021 aattcataac gcaggttatc agctgttggg ttctcttttt ccattttatc aattacatta
    52081 tctgtcaata cttgcgtaag atccgttttc caaaaatttt cttttgttag attattccgg
    52141 tcattcgttt tgttaatcat tgaatactga tctgttttat tgatataagc taaatcagtg
    52201 accccttgtt caatcagcga ccacgccacg ccttcgtccg aatttgtaat cgtagtcgta
    52261 tcattataaa atgttttaga aaactctatt ccactgtgaa tcaaagtcgg cattaaaaga
    52321 atcaatgcta ctgacattac aacattcatt ccaactgatt ttagatcaac cgttccttta
    52381 cctgtaatca ttttataacc aataatcact agtgaaagta tcattaagcc aacaacaatg
    52441 gtacttaaaa ctgattgata gactttattc aatccggtac tttctacaaa gctaaacaaa
    52501 tctaaaacct cgggaatcat attttgaata ccatcgacaa tagcgaacat tgattttata
    52561 acagaccagc ctatccacat accgaactgg ctgtaaaaat ttccgttata ttttttaaga
    52621 taattctgat aaagtggatt agttaaaaac tcagtttgac tctcagtatc atcaaaccag
    52681 ttgaaaatac tgccttctgc aacgttactc gtaaaaataa tcatagctat gagaataaga
    52741 aaactaatca acaaccaatt tatttttcta ttatcaatct tttttttaat tattttcatt
    52801 gttacctccc tcagcccatt tttttaggct ctcagaaagc ttctgagcca tttttttatt
    52861 aacgatgatg tgagttacgt aatcatcatt aacagctctt aaatctagaa caatagtatt
    52921 tgagcagata ctctcgatta actcaagagt atctgcgtta tgatcaagac agtaaatctt
    52981 atctactaga tgattttcaa tcaaaataac ccctcccgta gtcaaagttc tcaattttat
    53041 gaagatatcc ctctacttca tttaaatcaa ttctattctt attgctgact aacccgttgt
    53101 aaaattcttt ttgtagatta tatttatctg tttcttgaat ctttttatat aaatcaacca
    53161 gggagtccct gtctttaaaa acttgcttga attgttcgct tgtatatcgg ttttcattaa
    53221 ttgcaacaac tgcttgaatt tcaggccatt tttctttcaa cttaaaataa cggggaacgc
    53281 tgaaatagtt ctcaaaaaag aagtctcgtg cttcatagta ttctctattt tgtcttttta
    53341 tatcctcgac aatttcgtat cgtgtagaga tcttcaaagc tgaactttcg ttaatttctg
    53401 ttccttttcg aaagactttc acttttgaag ggcgttcaat tttataattt atcccctttt
    53461 tacttgaata acttttgata cgaccatcaa attgaaccat atctcctttt tttaaccacc
    53521 caaattttag aaattgttta gttaaattca tccaaatgtg gtctgtgacc aactctaagt
    53581 tatccccttg aacaattttt aaattcgata acataaaagt agcattttca tactcttgac
    53641 caaacttgta tttatccttt ttatatccgt taaattcaaa ggtaccttga aatgtatgcc
    53701 gtttcttatc tcctaatttt ttcaattttt ctctcaaaat aatcaactcc atcatttaat
    53761 atatttttgt gatggtagat actctcgatt aacacaagag tatctgcgtt gtaatcaaga
    53821 caataaattt gatatattaa ccgtttttca atcatattat taatcctttc taacctattt
    53881 ttttcagtgt ctctagcata tccagtctac tagctttttc ttgcttagct atgtcctccc
    53941 agtggttcct agctgtggtg ttgataaact tcatttcatc aatttcttca ccgagattca
    54001 gtttttcatt tatagaatta aaaagtcttg ttagcatttt gtttgttata tcaaaatagt
    54061 cttgacctcg aatttctatt ttatattctc tttcaattga atctttcata ctagcaatca
    54121 acttaagata cttttctctt tgaacttcag tatatctatc acctagtctg gtaattattt
    54181 gaattccttt ctgatttata atattttcaa aaaaggaatt ctgatcttga ttaatctctt
    54241 ctatactatc cttatcttga ttagtttgat cttgactatt ctgatcttga cttaactgtg
    54301 tatccgattt gacgtcgcat ggtataccag ctggatacca tttttccatc agatcaactc
    54361 ttaatggttc tacttgacca gactgcaaaa tcatatcaaa ttttattggc tttagctttg
    54421 agaaaaattc tggttttaag ttcaataact tgaatcgata aatagaaggt ttatacctat
    54481 cgattcgtat attttgattt tgtaaccagt ggggtagaaa cgctaacaaa tcttcattta
    54541 aaaaaaatac aaaacctttt gtaaaaagta tctttacatc atcatcgggt gttccgagca
    54601 ttttcgtgta tggataagct tcgacaattc cgtcatcatc tgcgtttgtg ttcagatata
    54661 cgtataataa ttttgctgaa tctgacatct tcataaaact tgcattattt aaaaatgatt
    54721 tagccagcat tcgtttttct gccataaaaa tcacacttct tcctatttga atgttaaaat
    54781 gtagtcaaat aaagtttagc tagaacttta ttattgagcg ttcctagtgg tctgcaaact
    54841 aacgggaaca ctctttttta ttcttattaa aaccagcaat actagttcac cttctttcat
    54901 ccttttacat ccaattaaat ttgatgctgt agcatccatt tttttacctc ttcttttgaa
    54961 tatagttcaa ttgtgtcaac cacgataata ggtaatccta accttttaaa cttcagaaaa
    55021 gttccatatg atacgtttag aaattttgcc atttcttttc ccttaagaaa aggtcgttct
    55081 aatccgctgt ctattcttgc ttgatcaata gcttcttttg tcacttcaaa cacatgtgtc
    55141 ttcaactgat ttgtttgatc agtattcaac attacactga ctccgatttg ctccattaaa
    55201 aattcccact ttcatatttt catcaataag ccaactcgcc aagttgtttg ttaataatct
    55261 gatttcaata accaacctat tattttttga taaacatttt tcgacacact ttgaacttcg
    55321 aagcattcaa tttttttaag agtttgcctt gaaattccaa ttaattctgc tgctttagtt
    55381 ttcgtaatca tcaactttcc tcgtctctct cgaattctta tactaaaatc ctcattaatt
    55441 tgaaacataa acatccctcc atttttattt ttgcatttat ccgtttatcc gatgtcggat
    55501 aaatagattt tagtatatat tattttgata gtcaattaaa aatatacatt ttggataaaa
    55561 ttgttcattt ttttatccaa atcatatatt atagatagta agaggtgaac ttcattgact
    55621 caaaaaaaca gaattaaaga aactcgcgaa gaacagaatt taacacttaa agaacttagc
    55681 aatctgtcgg atattccgta tcaaactttg agaaactatg agattggtaa aagaaaaccc
    55741 agaaatgatg aagtttggtg gaagttaggt acgattttaa acgtccgtgg gccctactta
    55801 aaaggagaag atagttttaa aacaaatgat gaattgcata tttattatct aaaaaaaagt
    55861 catacaaatt ttgaactgtc taagaaagaa gaaattatag atataataga taaactaaac
    55921 gaagacggtt tagatgaagc cttacggcag ttagcactat tatcaaaaat agatgatttc
    55981 aagcggtaac ttacttatca tcatgtagac tatcaggtat cataaactaa ttcctcaatc
    56041 agccaactcg ccaagttatc agattggaga gattagttat gtcaatacaa aagtacaaaa
    56101 caaaaagcgg tacacgatat agtgtccgct tatatgttcg taaagatgaa aatgggaagc
    56161 aagaatacta tgtaaaaaaa ggcttcaaaa ctgaaaaaga agccaagtta cacgaagcaa
    56221 gaaaaaaggt cgagattgaa gatatgggct atcacagacc ttctaatgac ttatttagaa
    56281 cagtctatga agaatggttg ccgtcttata aaaatcgtgt acaagaaacg acttatcaac
    56341 gaacaaaaga cctttttcgc ttgcatatcc tgccaaagtt cggagacaaa tcgatttcta
    56401 agattactcc tatttactgt cagaatgcaa tcaatgaatg ggctgtaaaa tatacaaata
    56461 tcaagcaact taaatcctac agctctcaaa tatttgagta tgcaatcttc gcagaattgt
    56521 tacagcgtaa ccctatgaca aataccaaac tgccaaaaca agaaaagaaa gaatccgaaa
    56581 attatttctc actagaagaa ttaaaagagt ttttggaaat tctcaataaa gaagagtctt
    56641 taaaacatat cctgatcttt caacttttaa ttactaccgg tgttcgcaaa ggtgaattat
    56701 cagccctacg ctgggcagat attaattttg aagaacagtt actacacatc ggaaaaagtt
    56761 atgcaacaat tcgcactgaa gatccgaatg ctactagaaa aacaatcagg attcagaaga
    56821 atacaaaaaa tgtctcttcc gaacgaattt taccgattga tactcaaacc atcgaaatgc
    56881 tgaaactttg gaaaaaagag caagcagagg tacttttaca attcggcatt aatgcaaata
    56941 ccaaaaagca acttatcttt acctatgtaa atgcaaatgg cgatgttaac caacctttac
    57001 acgcagatta ttccaataat attatgagac gtttagagaa gaaatataaa tttaagcacg
    57061 ttactattca tggattgcga cacactcacg ccactttact tttagaaggc ggtgcgagca
    57121 ttaaagaagc acaagatcga ttgggtcata aaaatgctga aactacgctc aatacttatt
    57181 cccatgtaac tgaaaaagcg caacgaaatg cggtagacaa gtttattgct tacactggat
    57241 tatagacaaa aaagttgccg tcattacctt tttcattacc acaacgaaaa aaagcacctt
    57301 ccaactgaat ggaaagtgct tgaaatcgtt ggtataacaa cgattaacgc ttagagaatt
    57361 gtgaagcttt acgagctttc ttaagacctg gttttttacg ttcgaccata cgtgcgtcac
    57421 gagtaagtaa gccagcacgt ttaagagcta aacggaagtc aggatcaact tctagcaatg
    57481 cacgagcgat accatgacgg atagctcctg attgtccagc gtatcctccg ccgtttacgt
    57541 taacaaatac gtcatatgcg ccttttgttt cagtaacagc gaaaggttga ttgattactt
    57601 cacgcaagtc agcatgtgga atgtattctt caacatcttt tttatttaca gtaattttgc
    57661 cagttcctgg tactagacgt acgcgagcaa ctgcgttttt acgacggcct gtgccgatat
    57721 attgaacttg tgccaatgaa attccctcct attagattaa gtttgtgatg tctaaaactt
    57781 ctggttgttg tgctgcatgt ggatgttctg ctccaccgta tacgttcaat tttgtaaatt
    57841 gtttgcggcc taaagtgttt ttaggaagca taccttttac agaagtttcg atcaaacgac
    57901 gagaattttt agcacgcaat tcgccagcag tgattgattt caatcctcct gggtagttgc
    57961 tgtgacggta ataaattttg tcagtcgctt ttttacctgt taatttcact ttgtctgcat
    58021 tgatgacgat gacgaaatcg ccagtatcca aatgaggtgt gaaagttggt ttatttttac
    58081 cacgtagtac agatgcaaca actgttgaaa gacgtcccaa tggaacatca gttgcgtcta
    58141 ctacatacca tttacgttct acttcgcctg gtttggccat atatgttgta cgcacgttat
    58201 tttcctccaa tttaagttct gatgtttgac atacacttcg agtttccggg gctctttgtg
    58261 gggcaaacaa taccatttaa catattaccc gctaatctag tcaatgtcaa cgtttttctg
    58321 cttgattgaa aaatttatat gaaactttac ttcttttctt tcttttatat aaaagggtcg
    58381 tttcctgtca aaatgaaaaa caaaaagagg ctgtgacaaa agtcttgtca caacccctta
    58441 ttttgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat atccataaaa
    58501 cataagaagc tgttttttaa aattgtttct tgtgactcgg agctgaacgg caggcttaca
    58561 acctcttggt aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    58621 atatgaggaa ctattttgac gtttgtttct ctaatactca ggtcaaaacg ctgatttcac
    58681 aacctctttt tcggtcaagt tcaacaacag tttttacgcg tcgatctctg gcgctttgcc
    58741 caaatgagct tggatcatcc agatacgttt ttctgtggct gttttgaatt cgataaagat
    58801 atcttgtgtt ggatcgtcgc cttcttctcc agaaacttcg attccttttt ggtaaagatc
    58861 tgctagataa cgatagcctg caacaagtgt ttccaaacgt tctggaatag tacgatccca
    58921 gcggccaatt tcatcaggga tttttgtgtt atctgcaaat tcacgcaatg tagaataagg
    58981 tgaaccgtct aatgtgatca agcgttcgga tacttcatct aactgagcgt tcaaatcatc
    59041 catgaactca tccatcattg ggtgcaatgt aaggaaacct ggtcctctca tgtaccaatg
    59101 tgtttggtga acaacaacag acatttggct tagatctgca actaattgat ttaatacttc
    59161 tttggtttgt tggaatttca tctttcttgc ctcctaacat tttcttacac ttaaaataat
    59221 agtagacttt caatgaaaag tacaacaaaa tcatttacct gagaacgatt ttcagttcgc
    59281 ttttttatcc gtaaagccaa tcatttttca gaatcagcta attcttctcg cagttgagca
    59341 aattgctgat aagtctgtgc taaatgcttt tgtgtcgaaa caaataatgg atagattttc
    59401 tgatattttt tatgatcagt ttcttgtact ccaacttgct ctttcaattc tatcaattcc
    59461 tgtgcttcac tgatactttg gatctttccg atgcttctcc agcctaaaat cacagctcct
    59521 aatgcggatg cttctgtgac agtagggaaa acaagcgggt aacccagtac atcagccatc
    59581 atctgacgaa aaatcggaga ttgagcaaac ccgcctgtag cacggatctc tgtgagctga
    59641 ttttcctggc aaactccttt taaaatccga taaaggttga gacagatccc ttctagaatc
    59701 gccttcatca tttctttttc tgtatgttgc cgctgtaaac cgataaaact gccaaacgca
    59761 tctgcgtccc aaagcggtgc tcgctcacca agtaaatagg gatgaaaaat cagaccattg
    59821 gcacccgctg gcacaaaagc gatagccgaa agcagtgcat catatggatt ttctcctttt
    59881 tctttagcag attgaacgac ttcctgtaaa aatgtatgcc ctgcccaatc aaagatgcca
    59941 gcaccattgc tagtcgctcc tcccactacc caatgtttct gatccagaac ataacaaaac
    60001 gtctccattt ctggatggaa ctgaggctga gtagtaataa aacgaagtgc tccgctcgtt
    60061 cctacggtca aagcggcgat cgtatcacca aaagcaccta accctagatt agaaagcggc
    60121 ccgtctgccc ctcccaaaac aaatgatata tcatttggca aacctagttc tgctgctgtt
    60181 tttgatggta gacctgttac ttgataggtg gaaggaaaga cttgcggcaa ttgctctatt
    60241 cgaatgttca agtagtcaag cacttcttct gcccattgga attcatggat atcaaaatat
    60301 ccagttcctg aagctgttcc gtagtcgctg atcagttcgc caaacaatct ataaaagata
    60361 tagtctttga taccgacaaa ataagcagtt tttttgaata attcaggttg gctgttttgc
    60421 agccacttga ttttgttcaa tggtgtcatt ggatgaatcg gcgtcccagt ctgccgataa
    60481 aattctttgc caagcacggt atatttcagt ttttctgctt cgtccgctgc tcggttatct
    60541 gcccaagtga tcattcgaga taacggtgtt ttctcttcat ccaacaatat caggccatgc
    60601 atcgcagagg agaaggagac aaattgaatg attgtgtctg aaggcaactg tttaattact
    60661 tcttttataa cggtgcagac accttgaaag atcaattcct gatcttgttc tgccatccct
    60721 tgtgtttctt ggatcaaagg gtagcgaaaa taagcggatg ctgcttcttg ggcttcatct
    60781 gtgaaagcaa ctgctttggt ttgtgtggtt ccgatatcta atccgattga aacgttcatt
    60841 ttttcacctc aaattttatg tatgtacaaa aatttagttt aagcttgcgt atcttggttt
    60901 tgaaaagggg gagatggcgt gttactttat tttatcattg gttgctgtat cggatcattt
    60961 ttatgtttaa ccgcccagcg gattccgtta ggtcactcta ttatttatcc tagatctcat
    61021 tgtgtcaaat gctgtcgttc gctttcttgg tatgaattga ttccgattct ctcgatcatc
    61081 gtccaacgat ttcgctgccg ctattgcagg tgtcggttgc ccttctacta tttgttggca
    61141 gaagccttat gtggtggtct ttttgcctgg ttctttactt tttcttccgc aagaaatttt
    61201 tcgacgttca tatggatgct ttcggctttg ctattttcgt tgatggattt attttacttc
    61261 atggtccatt ctcacacgct attctgttct tgggcaattt tatggatttt ttggttgcag
    61321 gccggcgtct tccaatggca aagtgtgctg ttaacgttta tcgtaggcgg tgtgtgcctt
    61381 cgctatggtc aatcctatct cggagctggc gatactctgt tgatgctttc ttggagtggt
    61441 ggcttgtctc tagaagagtt gcttcagatc ttgtttcttg ctagtctgtt tggaatatcc
    61501 gttttttctg tttactttat ctgtcataaa aaaaagttgg aaaagctgcc tttcattcct
    61561 tttttgagca gtgcgttgct gattgtcctt catcttaggt attgaaaaaa ggttgtgaca
    61621 aacgacttgt cacaacctct gatatatagt gttctcttac caaatccttg tgacttggag
    61681 ctaggcgaca ggttcacaac ctctccacta aatggtgttc aatcagctga ccctcagtat
    61741 tagctcaaaa tgctggtttt acaacctctg atatacggtg ttccataagt agctttttcg
    61801 gcttcttatt tcttgacgcc ccaatgtcga cgaaggaaac ctgcacgtcc agaaccttct
    61861 cgataaagat tgtaatggag cttgtttttc ttgtaataat cctgatggta atcttctgca
    61921 ggataaaatt cgcttcttgg ttcgattttt gtcacgattg gcttatcgaa tcgcccgctg
    61981 tcttgcaatg cttgttttga acgctctgca atatttcgtt cttcttcatc attatagtag
    62041 atcactggac gataagaatc accgcgatca gcgaactgtc ctaatgcgtc agtcggatcg
    62101 gtttgctgcc aatagatttc caccaactga tcataagaaa taacttctgg atcatattcg
    62161 atctctactg cttctgtatg ccctgttgtg cctgttgtta cttgttcata agttggattt
    62221 ggtacatgcc cgccagtata accggatgtc acagaaatga tccctggctg ctcttcaaat
    62281 ggtttgacca tacaccaaaa gcatccgcct gcgaaaactg ctttttttgt catataaaat
    62341 cccccttttt tctcatcata ccttgatttc caaaaggagg ataacgtttt gcttgtgaca
    62401 gaaaaaacgg aaactattat atacgtgata cggcttctga taaatgccaa aacgaacgta
    62461 cttgatcaaa aacggttaaa tcaggaatca catattcagc agaaggaaga tttatgtttt
    62521 cacctattcc caatacatgc atgttaccag ccaaagctgc ttgacaacca gcttctgaat
    62581 cttcaatgac caagcatgca tttggcggta cattcaattg ctgtgctcct ttgagaaaaa
    62641 cttctggatc aggttttgct tttgatactt gcgtgccgtc aataaggaca tcaaaataac
    62701 ttgtcaaatt cgttttttct aaaatgaggc gtgcattttt gcttgctgat cccaatccga
    62761 tcttgatgtt tgtttttttc aagtactcaa gaacagctat tgcaccaggc aaaacggatg
    62821 tttcatccat tttttgaatc gcttgaagat atagattgtt tttttgctca gcaaaggctg
    62881 atttctcttt ttctgagaat ttctgttcca tttttccaaa tgacagcaat cgctctagtg
    62941 actcggttct ggatattcct ttcagttgct cgttttcttt ctcagtgaat ggaatggaca
    63001 gctggttagc taaaaccagc cacgcttcgt aatgataacg agctgtgtct acaagaacgc
    63061 catctaaatc gaatagtgct gctttgattt tcatcgatta cctccttgaa aatgaacgac
    63121 ttgaagtaaa gatgcgatgt ttttagctgt gcgatgaaga ttatcagtgg cttgctgtaa
    63181 agcttcttgt aaaggcacag ctgcaggaag gatcggaaaa acggccgaaa tgccaacatc
    63241 tgctgctttt tcgcttcctt taccaacact tccgcaaata gctatcacag gaacgccctc
    63301 tggtactctt ctagcaatcc caactggcgc ttttcctttt agactttgtc catctagacg
    63361 tccttcgcct acgattacga ggtctgcttg ctgtacccgt ttatcgaact ccagtaaatc
    63421 caatacgtag tcgatgccag agactatttt ccctgaagca aatgctaaca gtcctgcacc
    63481 cattccacca ccagcactac tgcccgatgc ctcgattact tgaggggcaa atctcatata
    63541 aaaatcatgc atggcttggt cagccactgc taattcattt tctttcaagc ctttttgtgg
    63601 tccgaaaaca aaagaagcgc cttcttttcc gcataaaaga ttagtaacat cagtaatgac
    63661 agtgattttg gctttaatca gctcaatagg cacgttcgtt ttatcaactg tagcaatttt
    63721 acctagattt tctcccagtg cttctacttt ttgattatct tgatcgtaaa aagcataacc
    63781 tagaccttct gccatgccga tgccgccatc gttggtacta cttccgccaa cgccgatgat
    63841 gatgtgtcga acaccttgtt gcaacaattg tcgtatcagt tctcctactc ctcgcgtgga
    63901 taacctaagt ggctgttgtt ggtttagtgg gacatctttc aatccgacga tttctgccat
    63961 ttcaaaaatc gcagtttgac cgtctgaagc gtactggatt tctttgtttt tgccaaatgc
    64021 attagtaacg actgctgttt gccgcttcaa ccttaaactg tctgctaatg atgaaaccgt
    64081 tccttctcct ccatcgccta taggtagcag atcatattca gcctgaacaa aaacttcttg
    64141 aaaacctgat tgaatggctt gtgctgcctc taaggctgtc agactttctt tgaaagaatc
    64201 tggcgcaatc agaatacgca ttattttccc ctccgttcca agatcagttc tttttccagc
    64261 tggtattggt ctccattgac aaaaataggt aatgtttctt tcgtctcttt ttttattact
    64321 atttgttttt ttgtcaaaac aaatagcaac ctgtgatttt tccaaataaa aggaaaagaa
    64381 attttttccc atgctgaagg aagtcttgga gaaatagaaa gagttccatt cgttactgta
    64441 atacctgaaa aaccaaatat aactgctagc catagtgctc ctaatgaagc agcatgaatt
    64501 ccgtcatctg atgaatgcgg atctggtcct aaatcaatca ggcacgcttc ttggaataaa
    64561 tgatacgccc attccatttc ttggatacgg caagcctcta tggcgtgaat cgctttactc
    64621 aacgatgagt cgtggattgt tttgttttca tagtaatgca aattcttaga aacgattggt
    64681 tgagaaaaat actcaggtaa taagtataac agcatgacaa gatctgcttg cttgctgact
    64741 tggagttcat ttacttcgct acgggcataa tcaagtaaaa tagactggct gccaggacgt
    64801 tctttgtaag tggtcaaatc aataactggc ttactgagat acgtgtcatc ttgcggaatc
    64861 agctgttctt tgttaggcac tggcaaatat aacttatcta aaaaattttg acattctttc
    64921 aaaaaaagcg gatcgccagc ttgatattta acagctaagg ccacattata atgcgccaga
    64981 tagttcgtat atgcattatt gtcgatatat tctgtgtatt catctggacc aatgactctg
    65041 tgtatctcta aatgatcatc gacttttaca gctctgctca gccaaaaagc tgctgtttca
    65101 tgaatgagcg tttttccctt tgtttctaaa aacgattgat cctctgttgc ttggacatac
    65161 tcttgaacgg cataagcaag gtctgcactg atatgatgtt ctgcggcagc tgaagcaact
    65221 tcttgtcttg ttccggtttt gatattcaat gcagcaaatt tgggtgtctc ttcctgacca
    65281 gtgtgtgcgc tttcccatgg gaaaagtgca ccttgatagt gataatctct tgctttttgc
    65341 cgtgcgcctt ctaatcgatc ataacggtac agcagcaaat tctttgctac ttcaggaaac
    65401 tgatataaaa agaaaggcag gataaaaatt tccgtatccc agaaaacatg ccctttataa
    65461 ccttcgccag ttagtccctt cgcccctaca ctaacacttg gatcattgcg gggagtcata
    65521 atctgtaaat ggtaagcagc gaagtccatc gctaactgat cgaaagaaga atcgccttgg
    65581 atcgttatcc gatgctgatg ccaaaaatct gtccaataag acatcgactg ctctaaaatt
    65641 tctgtataac taacgctttt ctgggcttgg gcaatacttt tcttaaacgg gtctgtttgc
    65701 tgaagagagg tagagagcac gatgatcttc tccagcgtaa aggacgtatt ttttctgatc
    65761 ttttctgaaa aggaagcggt gatccggcga ttttttgctt ggaatacacc tgctttattg
    65821 aatttagctg caatcccaat atcaatttta ctttctgttg tctggtagga tgcactgatc
    65881 aaatcgtcac caaatactcg cagttctttt tcaaccaact gctgtgtacc aaaattggtt
    65941 tgctgtccat cgatacccgt tttcacatct acttggcagt cttcggtcaa cggcttgatg
    66001 accactttca gggctgcctg atggagatta ttttgatcag caacacgaca agtaatgact
    66061 tccacttttt ttccttgagc agtttcaatg agcgcatagc gtttaagctc tcccatttct
    66121 aaatctagtg cccgctcgta tgcaagaact ttcatcgtct caagagaaaa atgttcaccg
    66181 tcgattttta tttcccatct gatgacatct gggagattca ctaactcggc tgattctgct
    66241 cctaaaggtc ggttatatac accagctgca aacattcccc ttacttgatt ccgatagtct
    66301 tcctcctggc ttcctctgat accaaaaaat ccatttccaa tggtcatctg actcgcatac
    66361 ttattgatat actctaaatc aaactgtttt tcttctactt tcataaggta ataacttctc
    66421 ctgtttctgc cgaacgatat aaattttcca ccagattctg gatgacatat ccttgccagc
    66481 catctgcaat catctgagtc tggtcaccga gcgcccgatt cacaaaatga gccatactta
    66541 gttcatgtgg gtcattaact ggcgtggtct tttgtaagga aaccagcttt ccatctacat
    66601 cttcgaatag ttcgcctgga tacagattag cacctgcctg atcgccacaa aaagccacat
    66661 tcagtttgtc ttctctgata ttcaaagcaa acgaagtatt cagttggatg atcttgccgt
    66721 tttctaattc cagtgtgcca aaaattgcat cttctactgt gaatttgctt ggatcccatt
    66781 tcccgaattt ccctgaattt tttttcgtac caattttttg gaagctgtac gcccgaacgc
    66841 tttttacttt aggaaatcca gtaatataca tcgctgtatc aagcatgtga atgccataat
    66901 cgatcaaagg cccgcctcct tgaagttctt tgtcgataaa cgttccccag cctggaacac
    66961 cagaccgacg aagcgcattc gcttctacgt aataaatatc cccgagaaca tcaagatgat
    67021 tcttgatcat tgttgcttcg tcagaaaaac gatgctggaa tccataagcc aaaatctgcc
    67081 cgtttttatc ggctgtctct gccatctttc ttgcttgatc agctgtcata gctggtggtt
    67141 tctcgcacat cactgaagca ttagcttcga gggcagccaa tacatgttcg aagtgaaagc
    67201 gattgggtgt acagacactc acgatatcgg gagaaatctc attcagcatt tgtgtaactg
    67261 atgtatacgc atgagaaaat cctgtacgtc ggcaaaagtc ttctgctcgc tggctgactg
    67321 gatcaaccac agcggccaat tctaagacat ctgatctttt ttgataataa gcagcatgta
    67381 ctttttctgc tacttgtcca gcgcctatga ttgctacttt cttcatttat ttctctctcc
    67441 tttgcttatt tacttattgt tattctttct ctattctttc tctaaatcat ttaaatgacg
    67501 cgctgtttcc agacagtttt tcaagtattg caatgattcc tgataaattt tcacttcatt
    67561 ttctcctcgc aaacgacatt catataccat ataaccttca tactcatttt gaagtagcgt
    67621 ttgaaaatgg cgagtaaaat caattgcgcc agatcctggt tggtagcgat gattatctgc
    67681 taaatggata tgacccacat actctttttg cgtagtcaat gcttttgaaa tatcatcttc
    67741 ttcaatattc atatgataaa aatcagcgat gatctgcaca tgtttcaatt gattagagtc
    67801 aatgtaatga cgcgcatccg ctaacaaatt gatcatatgg tcttggtatc ggttcaaagg
    67861 ctccaaataa ataaccgtac ctgtttcttc ggctacttta tctaaataac gaagtgattc
    67921 gctgactgct ttatagtctc cttctttgct tcggggtgaa accatcggcg gtaatcgata
    67981 agtgaacatt ccccaagctg ctgggataac gattcctttg cctccaacct cgcttagtgc
    68041 acgcaaaatc tcagcaattt gacgtacacc attaagacgc cgttcttcga taaagtcacc
    68101 gatccaccca tcgtagccgt tacaagctgt cactactggg atccctgttt ctttgattgc
    68161 ctgtttgact gtgtcgatat tttctattaa caacttaccg tcgatttcgt attcttcaaa
    68221 tccacagtct ttgataaatc taaatttttc taaaatgtct cttgggaaaa atgcttgatc
    68281 ttgcgtaccg aatttcattg ttctcctcct cggacttgaa cgcccatttt gatactttct
    68341 tctgggtgct ggtctacata acgcatgtaa gcttctgcgc tttctgcaaa tggcacaact
    68401 ggatcaatga tttcttcaca atccaagtaa ccgttcatca ataattccca acatgtgtcc
    68461 tcgattcgtt tacggttcca tcttgggtaa tctgggtttg gttcactaga tgctcgagca
    68521 aagacgattt ttgcattatt gaaatgtgct tcgcgaccaa gattaaaccc agctggaaaa
    68581 ggtttagcaa aggcaacata agaaatgatc ccgccatagc cgatccctat taaagaagct
    68641 tgtaatgcgg cagcactgcc actcgtttca ataactgaat ctactccacg tttatctgtc
    68701 aattccttta gacgaaaacc gacatctgct ttcataggat ctagcgtgta atcggcaccg
    68761 tgtttttctg ctaattctct acgctgcgct atgggatcga tcccaacgat ggtagtagca
    68821 cctgcttttt tagctaattg aatcgcaatt tgcccgatag cgcctaaacc gaagattgct
    68881 acagcatcac ctgctcgaac atgtgcttcc cggataccac ctaaagcgaa ttgagcagga
    68941 tcgtaacata ctgcattttt ccattgatcc aaccgatcaa gtttacgtag tttataatta
    69001 tcaacaccgt ttgtaatcag cgtttcacga atgggtccat aagtgcagac taactctcct
    69061 ttttgatact ctgtcaccaa actgcccgtt tcttcgatcg taccgacaat catatttcct
    69121 aattgaaatt cgccaaatac cacaccgcgt tggcttcctt cttctcttgg caagaatagg
    69181 cgccattctt ctgaaaattc ttcatcgata aatggactta atcctctaaa gtcgacaatt
    69241 tctgttcctg gttttggagt agcgaaaatt actcggatac gtacttcgtt cttttcgatc
    69301 tcacggtctt cgtaatcttt gaatccggct attcttggtt ctaatgcaac taattttttc
    69361 atcttttctt tcctctttct tttcttttta tccttttacg ccgccttcga ctaaatcacc
    69421 tttaataaat cgttcagata acgcatacat aatgatgact ggtaaagcgg tcaccaatga
    69481 agcggccatc attcgtcccc aaatgtagtc tggtgtactg aataatgtgt tcaaaccgat
    69541 tggtaaagta aatttttcgg aggtcgacag gaaaatcgaa gcaaataaat aatcattcca
    69601 cgaaaccata aagcaataaa cgaagacaga aatgattcca gaaatagcca atggtataat
    69661 gatccgaata atgatctgga tccggctaag accatcgatc attgctgctt cttcaatatc
    69721 agtcggaatc gtgtcaaaat aactttttag catgaatatc gcagtaggaa gtgtttgaac
    69781 gaccatcgtg ataatcagtg ctgtattggt atcatacaaa cctagaccgg aaatgatttt
    69841 aaataatgga acaacgatca aaataccgga aaacatataa acggtgtaaa agctagcatt
    69901 gattttcgag cgagctttga agcgtagttt tgacaaagcg tatgccccgc tgatcccaat
    69961 cactactgca gttacggagg ctatcaagga gatcactaaa ctatttttga aatacatgat
    70021 gaatggaaaa atctcagcat tgaaaatatc ctgataatgt tcaaaagtcc attctttcgg
    70081 aaaaatagtt tgtgtcgttg caattgcttc ttgtgaatcc ttgaatgatg tcatcagcat
    70141 gatcaaaaat ggaaacaaat tgacagctaa tagcaacaaa atcgtcgcgt aaaataagat
    70201 tttcctgctc tttttatttt tcatttcaag tccaccttct ttcgtgagag caagacgacc
    70261 gctgcaataa tgatgaacaa tagaatcgat atagctgctg cttttccaag atcattgaac
    70321 gcaaaggctg tctgatacaa ataaacgcct aagatattga ctttattcgt cagtagatag
    70381 acatctgtaa acatatagaa catccagata gatcgtaaaa caatcacagt tgctagtact
    70441 ggtttgattg ccggcagtgt cacgatcttg aacttctgcc aagcatttgc accgtccatt
    70501 tcagctgctt cataaagcgt tttgtcgact gtttgcaaaa tagccaaaaa tgaaataaac
    70561 gcatacggat agtatctcca gatagcaaac aaaacgacca taaagaagct agcaactggc
    70621 tggtcgaacc acagcggtgc ttcgttgaaa agctgcaacc tatctactaa cagatcattg
    70681 acgattccat aactattatt gaacatatat ttccaagcaa aaatcaaaga aatagatggc
    70741 gtaacataac ttaataaaat cagtgaacgc accgttttcc taaatctgaa cttgcggtta
    70801 agcaaaatag ctacggctaa tcctaaagct gtactgcctg ctacaactaa gaatgtgtaa
    70861 gcaactgtta aacctaaaga acgataaaat tcactatcac ttaaaatttc aagataattg
    70921 cttaatccga taaaaacggc gtctgagtta ggattcagcg gcatatcgaa aaaactgatc
    70981 tgaatattgg aaagcattgg aatcagcact aaaacagcta ataaaagcat gcttggtgct
    71041 aaaagtccca tggctaattt taagtcagaa tgtttccttg gacgattcat tgaaacctcc
    71101 ccctgataat ctgccaatag ctatctactt ttttcgaaca ccattggcag aacttcttgt
    71161 tatttcgtat ttttttgtgc gtcagctaaa gcttgatcga catcttcgtt tccgacagtt
    71221 acttggttca ctgcttttcc gatcacacct gagcttgtga tatctcccat tttcgtgaaa
    71281 ttcttttccc cgactagtcc aaagacttgt acttcatcaa aagcactagc aatctcagat
    71341 ggcagctcgc caaaagactt gatgacttca ttttctttgt aaccatccag ttcgactact
    71401 tgtttattca ctggttgagc accaccagga gacatcaaga cccacttttc catgtttttc
    71461 ggttgagata agaaagctgt gaatgcttca gcagcctctt tttgtttctc gtctagacca
    71521 gaagaaatcg tcaatccaga tactgtgcca tagacagctt gatctttttg tgttgggata
    71581 gcaaaaccga tattttctga gttccccgct tcataaacag aaggcaaaat gtaagttgaa
    71641 tagattgcca ttggtgctgt tccattcatg aaagcatctt tgatttctgt cacatcatta
    71701 gagcctggca tcgtgtattg ggataagttt tgataaaacg acaatgcttc tctcatcttt
    71761 tccgtatcga tcgttacctc gccttcatca tccaaaacat ttgctccatt tgacaaagca
    71821 aattgagaga acgcttgctc actcattgtt ccttcagcag taggcatagc aattccatat
    71881 tgtttattct ctttatctgt gaaatgttga gcaattttta aaatatcatc ccaattttct
    71941 ggttctgaaa aaccagcttc tgataatttt tctttgtcat accaaatacc ttgaacccag
    72001 ccgctaattg gtgcagcaat atagcttttt ccatcttctg aacgaacaag gtttttggct
    72061 ccgtcataat aattatcttc tccagcttcc tcgataacgt tttggactgc cgtctgatca
    72121 atcagttcat ctttatccat cactttagca aaatcctgac tgacttccat tacttctggt
    72181 aatttaccgg aacgagctaa cgtaacgatt tttgtattga acgctgattc ttctaccggc
    72241 acttgcttga ttttgatgtc tggattttct ttttcaaaat cagcaaccag ttcattgatc
    72301 acacttaatc gttcctgttc gacagaagag tgcatgaatt gaatcgttgt ctgttgtgat
    72361 tcgttagagc tttgactttc accacaagca gtaagaagaa atccagtagc tagcagacag
    72421 gtagtaacaa taattttttt catttttttc cacctcttat tttattattt tcagccacat
    72481 atattcatac ggctggaata tcaactttcg ttcttgactg caatggataa tttgtccaga
    72541 aaacaggtct aggtaatctc cttttggtaa aagataacct gctgattgat tggaaaaatt
    72601 atggataact aagactttct cttccttcgc ttcgcgaata aaactgataa aagaatctgc
    72661 tgagtccagt aagtaaatca aactattcgg atggaaggct ttttcttttt ttcgaataga
    72721 tagcatctgg gtcaattcac catatactgc tgttcttaat ggatctgtct gcaactcttt
    72781 ctcaatatct gctaacaaaa atttttgccg attgattttt cgattctctc ctgttttttc
    72841 tacgcctttg taatcatttc gacttcccag cacactttga atataaattg ccggcacgcc
    72901 tggtaacgtt accaaaaatg aatgagcagc taaaaagcgt ttgcttctcc attccgtcgt
    72961 atctgttgga gaacttaacg catctagata cgtagcgttt atctcatatg gactggtcgt
    73021 tccatctggg tttttcttgt agtttactcg ggcaccctct ttcttcagct gttccactaa
    73081 ttcaaggatc gttttttccg gcagaatacc tcgtaccgga ttcaatccga taccgtcatg
    73141 ggaggctaaa aaattaaaaa aagttgtttt tttcgatgcg aaatcgatgg tttttaacca
    73201 ttctttcaac ttacttgtat tacccgaacg aatcgcttga agggtcaaag gtggtagcga
    73261 aaactgatag accatctgtg cttcattctc gccattccca aaataactga tattatcttt
    73321 gtgtggcaca tttgtctcag tgatcaatac cgttcctgga gctgcttcat cagcgattgc
    73381 acggaataat tggatgattt tatgcgtttc tggcaggtgt atacaagaag ttcctagttc
    73441 tttccataaa aatcccacag cgtccaagcg aataaatgaa gcgccttttt ctaagtaaaa
    73501 caaaagaata tcgatcattt tcaataaaac ttctggattt ttaaaattca agtctacttg
    73561 atcttcgcta aaagtcgtcc atacgtgttt ttctttcccg tttttgtcaa tgaacgttgt
    73621 aagtaacggg ctggtccttg gtctagtcac gctgcttgta tctgtatcca gtggcaaatc
    73681 aataaaaaaa tctttgtacg tatcattcaa gtttaaatat tcctgaaacc aagtactttc
    73741 ggcagacata tgattgcaga caaagtcgaa cattaaccgt gtttcgcttc tcatttcttc
    73801 tatatcttcc catgtgccca aacggtcgtt gattgcctga taatttacaa cggagaaacc
    73861 atcatcagat gtatatggga aaaatggcaa gaaatgtaca actctaaatg tatctgccaa
    73921 atacttttga taaaatttct taaatgtacg caaagttggt tgctgctctt caaaaaattg
    73981 atccccataa gtaatcaaga aaatatcttc ttcgtcccaa tgcagtttgc ctgcctggcc
    74041 tttcttctgc tgataaacac tgactttttg ttcaatcata gaggcggttt tctcagacaa
    74101 atctgagtcg cgataaatcg cttgtaaaag ttttgtatac atcggattcc cctttctttt
    74161 ttgggagcgt tcccaacgat ttgatcatat tatggaaaac gcttactgtc aatagcattt
    74221 ttttaaataa ttttgatata cacaaaaata caaataagaa agcttatgta tcaataatta
    74281 atagcttctt aaaaaaatat ggtctctcat gatcatgcaa gctattccta aattttcaaa
    74341 atcatagaca aaaaagaatg tctattgtac tatggaatta ttctaaaacg ctcccaaaaa
    74401 ggaggtgcat ataaaattga aacctactat ttatgacatt gcgaaaaaag ctaatgtctc
    74461 aaaatcaact gtctccagag tattaaataa ccagccaaat atctctgata aagcaaaagc
    74521 aagtgtactt caagcaatca aagaattgaa ttatgaaccg agcaaaattg caagaggact
    74581 gtcaggaaat ggttttgacg cgattctagc attatctcat cgtacttctc atacgaccta
    74641 tggcaatcct tttttttcag atgttattca atccatttct gccgtttctg aacaaaataa
    74701 cttcgacttg attctacaaa cggcaaaaac accagaagaa gagctagaaa aatgcgcgaa
    74761 aaagatccaa gaaaaaatga tccgaggaat tattatttta agctctacga tggatgaaac
    74821 acttcttttt gaattggatc aatataatat tcctattgtg gtaatcggaa aagtcggaaa
    74881 cgactacacg aacatctact cagtggacac ggataatttc caggatagtt acgatttggt
    74941 ggaaacactg atcaagaatg gacaccgtca tatcggctgt ctccatgctc cgacagaagt
    75001 ttatgtatcc aatgatcgtc tcaatggtta ccgtcaatgc ttatttgatc accacctaga
    75061 tatccgtaat gaatggatta tagacggcgg ctttcgctta gaagatagca tggcagcaat
    75121 gaatgattta atgaagctac gagaaagacc aactgcgatt ttttctaccg atgcattaaa
    75181 atcattgagt atttacaaag tggcagaaca atctggaaag cagatacctg atgatctttc
    75241 gatcgcagga ttcagtgatc ccttattgtc ctccctattt tcgccacagt tgactcggat
    75301 agacattccg acaaatcagt taggaatcaa agccacagaa cttttattcc aactaatcca
    75361 ccaccaatac cctgaagaaa aaagaatcat tctttcaacc gagattactc tcacagattc
    75421 gatccaacaa caagaaatgt agaacagaat tataaaagaa cagaaacact gaggataagt
    75481 cagttactct gttctttttt caatcactca tccctcgtta ccccctcccg gtattttagc
    75541 gaatttttct tattttccat ctgttttaga tagctgtgga taactataat gtttgtgtta
    75601 aactattttt tccacaggga agaaaaaact atttttaacc acgttgtgta taagttttta
    75661 tagttcgttt ttttaaacac atttaccctt atttcaatcc atgttatttg gggatactta
    75721 tctctaaaac ataaatagaa taacagacat gtctactggt tttgttttat tcgaggaatt
    75781 attcaataat agctagcaaa atattaaaaa taaccgctct atcttcccat caatttattt
    75841 tgcattcaaa aaatgatcta tctttacttt tgttgattga cttctcttgg aagatgatcg
    75901 ttccgatacc ttaattggat acgaaccgat gttgttaaga tcctttccca cttttcttct
    75961 agttagacaa attattttag acaaaccaaa aaagaggttg tgacaataat ttgtcacaac
    76021 ctctttttta aaatatctat tttgtttgat tgttcattgc gtcttctgca gccatttgcg
    76081 cttcaatatc tgaaatactg tagacatttt cgcttgctac accgacttct tttggttcca
    76141 tgtcacgata acgttgcata ccagtaccag ctgggatgat cttacctata ataacatttt
    76201 ctttcaaacc aagaagagga tctttcttac cgcggatcgc agcatccgtc aagacacgag
    76261 ttgtttcttg gaatgatgca gcagataaga aactatttgt ttctaatgat gcttttgtga
    76321 tacctagtaa gacaggtcga gaagttgcag gaacgcctcc tgagactagc gtattgtagt
    76381 tttgatcttt aaagtctgcg atgtctaata atgtacctgg taagatatct gtatcacctg
    76441 gatccattac acgaacttta cgcagcattt gacgaaccat tacttcgata tgcttgtcgc
    76501 cgatttctac cccttgcata cggtaaacac gttgtacttc acgaagcaag tagttttcaa
    76561 cagataatac atcgcgaact tgcaacaatt gttttggatc gattgatcct tctgtcaatg
    76621 gtgcaccacg gtggatcata tcgccttctg ctactttcat acgtgctgta taaggaacag
    76681 tatacgtacg tgtatctgtt tttcctttga ttgttacttc tttggtacgt gttgcaggat
    76741 cttctgagat atcgatgaca tcccctgtta cttctgtgat cactgcttgc cctttcggat
    76801 tacgtgcttc aaagatttct tggacacgag gaagaccttg agtgatatcg tctccggcaa
    76861 ccccacctgt atggaatgta cgcatcgtca actgagtacc aggttcaccg attgattgag
    76921 cggcgatcgt accaactgct tctccgactt caacgtcaga gccagttgca aggttgcgtc
    76981 cgtaacaatg tttgcagaca ccatgttttg tattacatgt gaagacagaa cggattgtca
    77041 ctgtttcgac acctgcatca acgatttgtt ttgcgatgtc ttcggaaatc aattggtttc
    77101 ctgcaatgat caattcattt gtttcaggat gacgtacttc tttacgggtg taacgtccca
    77161 ctaaacgatc ttctaatgat tcgatgattt catttccctc gcggatggct tggatttcaa
    77221 gacctcggtc agtaccgcaa tcttcttcac ggatgattac atcttgggcc acgtcaacca
    77281 gacgacgagt caagtaacct gaatcggcag tcttcaaggc tgtatcggtc atccctttac
    77341 gagccccgtg agttgagata aacatttcca agacggatag tccttcacgg aagttcgaaa
    77401 tgattggcaa ttccatgatt cgaccattag gagcggccat caaaccacgc attccggcaa
    77461 gctgtgtaaa gttggaaatg ttaccacgag ctccagaatc agacatcatg aagattggat
    77521 ttttcgcttc caaaccttcc atcagttttt gttggatgct gtcttttgca gcattccaaa
    77581 cagcaatgac acgttcataa cgttcgtcat ctgtgatcag accacgacgg aattgttttg
    77641 taatagtttc aacttgttta tgggcatttt caatgatttc ttgtttttca ttcagtacac
    77701 tgatgtcagc gatccctact gtgataccgg catgtgtcga atgtttgtac cctaagtctt
    77761 tcatacggtc aagcatctta gaagtttctg ttactttgaa tcgtttgaag acttctgcga
    77821 tgatgtttcc taagtttttc ttcttgaacg gtaatactaa ttcttgctct ttgatatgtg
    77881 caggaatatc agtaccagct tcaacaaagt atttgtccgg tgtttggacg gtcaagttga
    77941 agtctgttgg ttcattcaga taagggaatt caggaggcat gatctcgttg aagatgatct
    78001 taccaactgt tgtgatcatc gtacgttctt tttgccattc agtaaatggt ttttcaccta
    78061 atgagttagg gttcacaccg atacgtgaat gtaaatgaac atatccgttg cgccatgcga
    78121 taacggcttc gttttgatct ctgaagacca ttccttcgcc ttcgcgtcct tcttcttcca
    78181 ttgtcaagta gtagttacct agaaccatat cttgagaagg agtaacaact ggtttaccat
    78241 ctttagggtt caagatgttt tgagcagcta acatcaacat acgtgcttct gcttgtgctt
    78301 cttcattcaa tggaacgtgg acagccattt ggtctccatc gaaatcggca ttataagctt
    78361 cacatacaag tggatgcaaa cggattgcgc gtccttgtac taaaactggt tcgaatgctt
    78421 ggataccaag tcggtgaagc gtaggtgccc ggttcagcaa tactgggtgt tccttgatta
    78481 cgtcttctaa aacatcccat acttcgtctt cttgacgttc gattttacgt ttcgcatttt
    78541 tgatgtttga agctagttcg cgttgaacaa gctcacgcat cacgaatggt ttgaataatt
    78601 caatggccat ttcttttgga agtccacatt ggtacatctt caagaaaggt ccaacaacga
    78661 taacggaacg acctgagtag tcgacacgtt tacctagcaa gttttgacgg aaacgacctt
    78721 gtttcccttt caacatatga gaaagagatt tcaatgggcg gttacctggt ccagtaactg
    78781 gacgtccgcg acgaccgtta tcgatcaatg catctactgc ttcttgcagc atacgttttt
    78841 cattttgaac gatgattcca ggtgcattca agtctaacaa acgtttcaaa cggttattac
    78901 ggttgattac acgacggtaa agatcattca agtcacttgt tgcaaaacgt ccaccttcta
    78961 attgaaccat tgggcgtaaa tctggtggaa taacagggat aacgtccata accatccagc
    79021 ttggttgatt tcctgaagcg cggaatgctt ctaaaatatc caaacggcgg attgcacgtg
    79081 tacgtttttg tccttgtgca gatttcaatt cttctttcaa ttcggctgct tctgcatcta
    79141 gatcaacatt atcaagtaat tgtttaatcg cttctgcacc catagcagct tggaattctt
    79201 gtccatattg ttcacgtttt tcgcgatatt cgcgttctgt caacaattgt tttttctcta
    79261 aattcgtatt tcctggttcg atgactacat atgaagcaaa ataaatgatt tcttccaaag
    79321 cgcgtgggct catgtctaat acaagaccca tacgtgaagg aatcccttta aagtaccaga
    79381 tatgtgaaac aggagctgct aattcaatat gtcccatgcg ttcacggcga actttcgaac
    79441 gagtaacttc cactccgcat cgatcacaaa cgattccttt ataacggata cgtttgtatt
    79501 ttccgcaggc acattcccag tcttttgtag gaccaaaaat ccgctcacag aacaaccctt
    79561 cacgttcagg ttttaaggta cgatagttaa tcgtctcagg tttttttact tcaccgtaag
    79621 accagcttct gattttttcg ggagaagcca aacctatttg catactttcg aatttattta
    79681 catcgatcaa aaggggttcc ctccatttca tttaatggca aaccgcaaga cggctgatct
    79741 tcgaccgcct tgcagctcat agaccggatt agtctaaatt atcttctgcg gtttcaaagt
    79801 tttggatgac atcgtctttt tcatcttcca cttgttcagc agctttcttt tctaattctt
    79861 tggcagtttg ctgttcggca aattttgtca aagcatcaac agtgatcaaa tcgtcgtctt
    79921 catcgtccat gtcgcgaagt tcgatctctg tttcttcgat atccaagaca cgcatgtcca
    79981 gacctagtga ttgcaattct ttcaccaata cgcggaatga ttccggtaca cctggttttg
    80041 gaattggttc acccttgacg attgcttcgt atgttttcac acgtccgact acgtcatctg
    80101 atttgtatgt caagatttct tgtaaagtat aagccgcacc gtaagcttcc agtgcccata
    80161 cttccatttc accaaaacgt tgtccaccaa attgagcttt acctcccaat ggttgttgtg
    80221 taaccaatga gtaaggtccg attgaacgtg catgcaattt gtcatcgacc atgtgagcaa
    80281 gtttgatcat gtacatcaca ccgacagaca cacgtccatc aaatggttca cctgtacgtc
    80341 cgtcgtacag aacagttttc gcatcgctgg ccataccggc ttcacgaact gtttcccata
    80401 cgtcttcatc acttgcacca tcaaatactg gcgttgctac gtggatacct aactgacgtg
    80461 cagccatacc caagtgtaat tccaatactt gcccgatgtt catacgtgaa ggcaccccta
    80521 aaggattcag catgatatcg attggtgttc catcaggtag gaatggcata tcttcttccg
    80581 gcataatacg ggatacaacc cctttatttc cgtgacgacc ggccatttta tccccttcat
    80641 ggattttacg tttttgaacg atataaacac gaactaacat gtttacgcct ggtgacaatt
    80701 catctccagc ttcacgagta aagattttca catcgtgaac gataccgccg ccgccatgtg
    80761 gtacacgtaa tgatgtatcg cggacttcac gagctttttc gccaaagatc gcatgcaata
    80821 gacgttcttc tgcagataat tctgttaccc cttttggcgt gactttccct acaagcaaat
    80881 cgccatcttg gacttctgca ccaatacgga tgatacccat ttcgtctaaa tcttttaatg
    80941 cgtcttcccc gacattaggg atttcgcgtg tgatttcttc aggtcctaat tttgtatcgc
    81001 gggcttctga ttcatattct tcaatatgga tagaagtgta tacgtcatct tttaccaaac
    81061 gacggctcat gatgatcgca tcttcatagt tgtacccttc ccaagtcatg aaaccaacta
    81121 aaacgttttg gcctagagcc atttcgcctt gttccataga tggtccgtct gccagagtat
    81181 cccctttttc gactttctca cccaaatgaa cgattggacg ttggttgtag cttgttccgg
    81241 agtttgaacg acggaatttt gttacatcgt atttatctaa tgcaccgttg tcgcggcgta
    81301 cgcggatttc agaagcatca acgtattcaa cgacaccgtc atgtttacat aacaaagcag
    81361 ctcctgagtc atgcgctgat ttgtattcca taccagtacc aacccatggt gcttgaggat
    81421 tgatcaacgg cactgcttga cgctgcatgt tggcacccat caaggcacgg ttggagtcat
    81481 cgttttccaa gaaaggaata catgctgtcg caacggcaac tacttgttta ggtgatacgt
    81541 ccatgtagtc tactttatca atagatactt ctaagttttc actttgagca cgagccataa
    81601 caacgtcttg agcaaatgtt ccatcttcat tcaatgggct gtttgcttgg gctacgatgt
    81661 aatggtcttc gatatcagct gtcaagtagt cgatttggtc agtaacacga cctgtttcac
    81721 ggtctacacg acgataaggt gtttcgataa atccgaattt atttactttc gcataactgg
    81781 acaaactatt gatcaacccg atgtttgggc cttcaggagt ttcgatcgga cacatacggc
    81841 catagtggga gtagtgaacg tcacgaactt cataaccggc gcggtcacga gtcaatccgc
    81901 caggtcctaa ggctgaaaga cgacgtttgt gtgtcaattc gccaagaggg tttgtttgat
    81961 ccatgaactg tgacaactga gaagaaccaa agaattcttt gatacttgcc acaactggac
    82021 ggatattgat caattgttga ggtgtcaatg tttcagtatc ttggatcgac attctttcac
    82081 gaaccacacg ttccatacgt gctagcccga tacggaattg gttttgtaaa agttcaccga
    82141 ctgaacggat acgacgattt cctaagtggt cgatatcatc gacattgccg ataccttcca
    82201 tcaagttcaa gaaatagctc attgaagcaa tgatgtcggc tggacgaacc gtttttacag
    82261 ctgcttctgg atagccgttt ccgatcacgt ttacttcacg ttcagggtct cttggtgaaa
    82321 atactttgat gacttggaca gtcattggat ctgtgaccac accgtcttct gatggatagt
    82381 aagtcactga atttaggcca ttatcaatga aaggagctag tgtttccatg acttggtgag
    82441 tcagaactgt tcctttttca acgatgatct cgcctgtttc tggatcaact aatgtttcag
    82501 ctaatgtcag attcaataga cgtgttttca aatctaattt tttgtttact ttgtaacgac
    82561 caacgtttgc taagtcgtaa cgttttggat cgaagaaacg agcattcagc aagttacgtg
    82621 agctgtctgc tgtttttggt tcgcctggac gcaaacgttc gtaaacgtct ttcaaacctt
    82681 cttctgttct tgagtcgctt gcgtttttat gcaagtcttt ttcgactgta ttgcgtaatg
    82741 tttcgctgtc gccgaagatt tcaaagatcg tatcatcgga accaaatcct aacgcacgaa
    82801 ctaatacggt taaaggaatc ttacgtgtac ggtcgatacg tacataagag atgtcttttg
    82861 catcagtttc catttctagc caagctccac ggttagggat aacagtagaa ccgaatcctt
    82921 cttttccgtt tttgtcgact tttccatgga aatagacacc tggtgaacgg actaactgag
    82981 aaacgattac tcgctctgcc ccgttgatga tgaatgttcc ttgttctgtc attaatggga
    83041 aatcaccgaa gaatacttct tgtgctttga tttcgccagt ctcgcggttt gtcaaacgca
    83101 atgttacatg taatggtgca gagtagtttg catcatgcgc acgagcttct gctactgtat
    83161 actttggttc tttcaattca taatctacaa attccaaaga tagattgcca ttgaagtcat
    83221 cgattggcaa aatgtcttca aacatttctc taagtccctc atctaagaac cattggtaag
    83281 agtctgtttg aatttcgatc aaatttggta attccaacac ttcactgatt cttgcgaaac
    83341 ttctacgttc gcgatgtttt ccgtatttta ctacgtgtcc agccaagctc ttcacccctc
    83401 taaaatgtca ttcaaaaaga ctacccgatc aattgttaca ataatatttc aaatattatt
    83461 tttaggtaac aacagacatt ttttgcggct tttaggcaaa aaaaaaccaa aaatagaaca
    83521 ttctcttgaa accttacttc gtgagcttct acttttgttt ccttatatta aagccgaaac
    83581 ggacaatatt tcgtttctgc cttttcttca tcagatagtt tttgcaactt catatactac
    83641 acttattttc tataaaagtc aacacttcct ggcgtttctt ctgctttttc gcaacatttt
    83701 cttaatgttt tcaattttat gttttcaatt atctgacaat tcttaattga cagacctttt
    83761 tatctcggtt atactttaga aaattcattt tgtggaggaa cttctatgcg aaccaacatc
    83821 aaccaaatcg caccaacaca actgaataac ttttacttta gctactttag ataggtttgt
    83881 attcatcatg atggatacaa acgttaaacg acagtttgta tctatgatgg ctaaagaact
    83941 ttgtattgca gcaaaaagcc acgtagacaa aatgctaagt ggctgagcag tgaaaataca
    84001 aagtaaaagt atcaagcatt ctactttttc aatttatttt ccgacttttc aatccatttg
    84061 gacattttgt ctgaatggat tttttgtttc ccaaaattaa ggaggaaaaa gaaatgaaaa
    84121 aaaatataat catcggatta ggcgctgccc tgctactagc tttaggaggt tgcgcacaaa
    84181 aagacaattc cgcagaggca tcagatggac aaaaaacaat tggcgtattg caacttgtac
    84241 aacataactc gttagatgct gcctataaag gattcaaaga aggattagca gaagaagggt
    84301 ataaagaagg cgataatcta acaatcgatt atcaaaatgc ccaaaacaat caagacaacc
    84361 tgaaaagtat gagtgagaaa ctcgtcaaag aagatcctga tttgctactt ggaatcgcca
    84421 ctccagcagc acaatcttta ttaaatgaaa caaccactat cccgatgact gtcacagcgg
    84481 tcacagactt ggaacaagcc catttagtca catccaatga aaaacctggc ggcaatgtga
    84541 ctggcacgac agatatggtg ccaatcgaaa aacaaatcgg cttactgtta aatatcgtgc
    84601 cagacgccaa aacaatcggc atcatgtata acaacggtga agcaaactct aagatccaag
    84661 ctgatttggc agaaaaagaa ttgaaaaaag cgggcgtcaa agtcaaagta ctgacagcaa
    84721 attccacaaa tgatgtccaa caagtgacga aaagtctagc taaagatgta gatggaatct
    84781 atattcctac tgataacacg ttcgcaagtg cggcaagtgt tgtcggtgaa gtcgcaaaag
    84841 aaacaaaaac acctgtcgtt gctggcgcag ttgatcaagt caaagacggc ggtctagcaa
    84901 cagtaggaat cgactacgaa agcttgggca aacaaacagg gatcatggca gcaaaaatct
    84961 tagacggcaa gaatccaagt gaacttcctg tcgaaacagc gaatgatttg gaactgtatg
    85021 tcaataaaga catggccaaa gcattaggca tcaatccaga cagcatcaaa gaagctgaat
    85081 aaaacacagg aggattctca tgacaaattt gctctctctt ttcttatcat ctgcatcgca
    85141 aggggtctta tgggccctac ttgcgattgg tgtatacgtc actttccgta tcttggacat
    85201 tgccgacttg actgctgaag gaagctttcc tttaggtgca gggatcgcgg cagtaagtat
    85261 tacaaatggc tatcatccat tgacagcttg tcttctaggc tttttagggg gtgcggcagc
    85321 agggcttgtt tccggactgc ttcacacaaa attgaaaatt cccgcccttc ttgcagggat
    85381 catcaccatg actggtttat attctgtcac atcccgtgtg atgggtgcgc cgaacatctc
    85441 tttattgggt cagccaacga tctttcattg ggtcgagtca ttcggcataa caaaagacaa
    85501 cgctgtactg atcgtcggtc tgctttttgc tttgatcgtt gtatgtttac ttgttttgtt
    85561 cttacgtaca gaaacaggac ttgctattcg tgcaactggc gataatctgg caatgagcga
    85621 agcaaacggg atcaacacag ataatatgaa gatcatcggt tatatgattt ctaatggatg
    85681 cattgctctt tctggctcct tacttgcgca aaacaacggc tttgctgatt taaattctgg
    85741 tattggaacg atcgtaattg gacttgcttc tattatcatc gcagaagttt tgttacgtaa
    85801 ccagccacta tttctccgtc tcttgactgt cgttttaggt gcggtcattt atcgttttat
    85861 tttagcgtta gtcttcgaac tgaatgttga accaagtgat tcgaaacttg cttctgcttt
    85921 cgtgctagtg atctgtcttt ctttcccgca gatccagcaa aaattccatt tacctcaaaa
    85981 aaagaaaggc ggtagtgtca aatgaatgac gtcttaacat tggaaaatct ccatcatacc
    86041 tttgaaaaag gaacgatcaa cgaaaatcat gtcctgaaag gcattaatct ttccttagat
    86101 cccggcgact tcgtgacgat catcggtgga aatggggctg gtaaatctac tttgctgaac
    86161 agcatcgccg gtacattttc tgtcgatcag ggtcaaattt tattgaatgg aaaaaatatc
    86221 acgaaaaaat ctgttgtcga acgttcgaaa tccatcagtc gcgtattcca agatcctaaa
    86281 ctagggacag ccgttcgttt aacggtagaa gaaaatcttg ctcttgctat gaaacgagga
    86341 aaaaaacgcg gcttcttccg tggtgtcaaa ccacaagacc gaacattttt caaagaccag
    86401 ctggttcggc taaatttggg gttggaaaat cgtttatcct cagaaatcgg tttgctgtct
    86461 ggaggacaac gtcaagctat tacgttattg atggccacat tacagcgtcc agaactgatc
    86521 ttattagatg aacacactgc agcgcttgac cctgctactt ccaaaacggt gatggaattg
    86581 acagaaaagc tgatcactga gcagaatctc actgctttta tggtcactca tgacatggaa
    86641 gacgcgatcc gctatgggag tcgactgatc atgctgcatc aaggaaggat cgtcgtagat
    86701 atccagcaag aggaaaaaca gcagctcaca gtgccccaat tattagcgtt gttcaaacaa
    86761 aacagcggca cggcattaaa agacgatcaa gtacttttat cttcataatc agaaagagga
    86821 tgggacaaaa aatgaacgcc caccctcttc ttttttctct ttccttcttt cgtttttgct
    86881 ttatgtatca accgttgttt cttcgaaaac tattttgttc tctccttctt cctgatagaa
    86941 tggatgggaa aggagcttga tgccatgaca acgaaagaca aggtacttca attattgaaa
    87001 aagacaccag attttctttc cggagaaaag ttggcacagc aactggaagt ttcccggaca
    87061 agtatttgga aagccatcaa agaattggaa aaggcaggct atcgttttga gcacgggcct
    87121 acagggtatc gttacctgcc ctctgacgta ctagatgcaa aagaaatcca gcaagagcta
    87181 cggtcgttta ttcctgattt gaaagtacaa acgatgttga cttctgaatc tacgatgaaa
    87241 gatgccaaac tggcagcagc tcaaggagat tctgtttcga agttatttgt tgctgataca
    87301 caagaacaag ctcgtggacg ttttggacgg ccttttttcg ctgaacctgg acgaggaatc
    87361 tacatgagtc tcttgctcca tccagacaaa cggtttgatg aattgcctca atatacgatc
    87421 atcgcagcca gtgcctgtgt gaaagccatt gaatctgtaa ccggtcgttc tgcttcgatc
    87481 aaatgggtca atgatatcta catggatgga aaaaaagtct gtgggatttt atctgaagca
    87541 gtcagtgata tggaaagcgg caggatcagt catatcatca ttgggatcgg gcttaatttt
    87601 tctgttcctc aaaatcattt tccagctgat ctccaagaaa aagccatctc tgtctttccc
    87661 gacggacaag ctagtgtcac aaggaatcag ctaatcagca aaatctggca agaattgttc
    87721 acttatcttt ctcacccaga aaaagcgttg gacttctata aagaaaaatc attcgtattg
    87781 ggaaaaaccg tgtcgttcaa tcaaaaagga acgacttatg tcggtcttgc aaaagaaatc
    87841 ggtgatcatg gcgaactgat cgtccaaaca aatgaacaga agatgagttt gtcttctggc
    87901 gaaatcagtc tcacatctat ccgtacgcaa taattatcag atttcacaaa aggacacctg
    87961 atctcataca gtgtcctttt ttctgaattc tcttcaaaag actctcctta ttctatcagc
    88021 tgacagtttc tctatcctct agaaaaaggt attctaaaaa tatctataaa gcatggtaca
    88081 ctttctttaa atgaatcaat gcaaaaaaca agagagtcat cagtttacac gatcaaaaga
    88141 gatagcaggc cgcttccttt ttcaatctta tagatagacc atgggtaacg ataaaaacaa
    88201 aaaagaactt gcgacttatt ttgccgtaag ttctttttta gctagtgcct taatctctta
    88261 atcccaacaa acgtctcgca tagatcacct gaccagagtg catagcagca tcatcaataa
    88321 tagaaacgag acgcattcct cgtgtgactg gtggtgtcca gttctcgtca attacttcat
    88381 ctagctcgga aggttccagc cttcttaagt aagaaatagc aaaatcagca gctcctcgca
    88441 agtatcctag cagatcttct atttgattag cttggatctg ctttgcttgt tccagactat
    88501 gcttccaatc ttgttcgtta tctgctatcg tcatcggaaa ccggctttcc cagtcttgac
    88561 tatgccaaat tggagaagtt cctgctaaat cagcaatctg gaaatctaat tctcgagcgg
    88621 tatgccaagc cagccaagtc attgatttga tctgcggggc tctatcttcc actggaaaac
    88681 gattggcctc ctcaatagag acgccttcaa acaaacgttc aaaccgatcg tatgcccgat
    88741 ccacactctc gcatagcata tctaaataat ccatttattt tcctcctttt tatttatcct
    88801 acttactttt tcctaattct aggataccta cttatatgtt actacacacc cttatttttt
    88861 acactttaac agtcaccatc atcaatagtt tggagattga aagaaaaaga tagtgtcgaa
    88921 ctatcaattg aacaagaagc aacaatatga acgtttcatt aatattcttt aaataaacaa
    88981 tgatttttca aacgaacagt ttaagactag gagaaaaaga gtataatagg aaaatgtttg
    89041 aaaggaaagg aaggggaaaa atgaaaaaaa gggcaagttt actagtccta gttgctttgt
    89101 tgttcaatat cttttcgtat ggtgtggccg tttcagcgga aacatacatt cctaaagacc
    89161 ctgggaatat ttataatgat ctaactggta actatggctt gttaggaatt gctagtcaat
    89221 tccacgtatt tgctaaaaat aagacaactg tgaatgcaca tacagacgga aatatagcaa
    89281 cacatgaact tgatgcaaaa aataattttg gtacagagct tcatgaaggt ttattgaacc
    89341 aagaaataaa ttatatacaa aaaactgatt ctttcgctaa ttcttcaggc atacctacag
    89401 gtagcacaag aatgaataaa tttgtcgttg gcagtaacgt ggatgtagca cttcaagatg
    89461 gtcatcctac agtcaatgga tccaggcttg atcacttaac tccagatgat ttttataaag
    89521 atcgtgctgg gcatgaatat attgatttcg agcaggaatt tgctaaattg aatgtagcag
    89581 caaatgatct tgcaacgatc actccagcta aaacatatac tgctgcagat tttccagaca
    89641 tgaacaatcg gacaatcgat ttaactgatt tatcagatac cgggttttta ttggtaaata
    89701 tcgatgcaga agtgttaacg atgaatacgc cacttcaaat cattaatcca aatgatcaag
    89761 tagttgtatt taatgtcatc aacagttctt ctgcattgaa cgtacagtca ccaatcaaat
    89821 acaatgatcg ttcaaatcat gaaacagaag atttttcgga tgcgaatatc tcttggaatt
    89881 ttggaaatga gatgactgat ttgacaatca gtgctccttt tcaaggaaca atccttgcgc
    89941 ctaatgctac tatccgcatt actcaaaacc aagacggaac gattatagga acaaatgtga
    90001 ttttagatgc agctaccaat cgttgggatc ctaacgaaat atttatcagc gacaatggta
    90061 cagatacgac agacacaagc gacagtacag atacatctac cacaagtgat agctcagatt
    90121 catca
//
LOCUS       DBGZHO010000005        80176 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.005, whole genome shotgun sequence.
ACCESSION   DBGZHO010000005 DBGZHO010000000
VERSION     DBGZHO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 80176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.005"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            210..446
                     /locus_tag="ACN3HL_000492"
     CDS             210..446
                     /locus_tag="ACN3HL_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005399.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            453..2405
                     /locus_tag="ACN3HL_000493"
     CDS             453..2405
                     /locus_tag="ACN3HL_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HHC8005400.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2477..2974)
                     /gene="dfrG"
                     /locus_tag="ACN3HL_000494"
     CDS             complement(2477..2974)
                     /gene="dfrG"
                     /locus_tag="ACN3HL_000494"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HHC8005401.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3249..4376
                     /locus_tag="ACN3HL_000495"
                     /pseudo
     CDS             3249..4376
                     /locus_tag="ACN3HL_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
     gene            4474..4662
                     /locus_tag="ACN3HL_000496"
     CDS             4474..4662
                     /locus_tag="ACN3HL_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HHC8005402.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4720..5073)
                     /locus_tag="ACN3HL_000497"
     CDS             complement(4720..5073)
                     /locus_tag="ACN3HL_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005403.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5604..6026
                     /locus_tag="ACN3HL_000498"
     CDS             5604..6026
                     /locus_tag="ACN3HL_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHC8005404.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6023..6253
                     /locus_tag="ACN3HL_000499"
     CDS             6023..6253
                     /locus_tag="ACN3HL_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005405.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6751..6951
                     /locus_tag="ACN3HL_000500"
     CDS             6751..6951
                     /locus_tag="ACN3HL_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HHC8005406.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            6978..8171
                     /locus_tag="ACN3HL_000501"
     CDS             6978..8171
                     /locus_tag="ACN3HL_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005407.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8239..9804)
                     /gene="guaA"
                     /locus_tag="ACN3HL_000502"
     CDS             complement(8239..9804)
                     /gene="guaA"
                     /locus_tag="ACN3HL_000502"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HHC8005408.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9863..10786)
                     /gene="coaA"
                     /locus_tag="ACN3HL_000503"
     CDS             complement(9863..10786)
                     /gene="coaA"
                     /locus_tag="ACN3HL_000503"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HHC8005409.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10982..11587
                     /locus_tag="ACN3HL_000504"
     CDS             10982..11587
                     /locus_tag="ACN3HL_000504"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8005410.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11895..12911
                     /locus_tag="ACN3HL_000505"
     CDS             11895..12911
                     /locus_tag="ACN3HL_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8005411.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13052..14353
                     /locus_tag="ACN3HL_000506"
     CDS             13052..14353
                     /locus_tag="ACN3HL_000506"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HHC8005412.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14399..15061
                     /gene="deoC"
                     /locus_tag="ACN3HL_000507"
     CDS             14399..15061
                     /gene="deoC"
                     /locus_tag="ACN3HL_000507"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HHC8005413.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15082..15480
                     /locus_tag="ACN3HL_000508"
     CDS             15082..15480
                     /locus_tag="ACN3HL_000508"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HHC8005414.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15546..16628
                     /locus_tag="ACN3HL_000509"
     CDS             15546..16628
                     /locus_tag="ACN3HL_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8005415.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16840..18402
                     /locus_tag="ACN3HL_000510"
     CDS             16840..18402
                     /locus_tag="ACN3HL_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005416.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18395..19528
                     /locus_tag="ACN3HL_000511"
     CDS             18395..19528
                     /locus_tag="ACN3HL_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005417.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19528..20484
                     /locus_tag="ACN3HL_000512"
     CDS             19528..20484
                     /locus_tag="ACN3HL_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005418.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20583..21749
                     /gene="deoB"
                     /locus_tag="ACN3HL_000513"
     CDS             20583..21749
                     /gene="deoB"
                     /locus_tag="ACN3HL_000513"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HHC8005419.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21773..22591
                     /locus_tag="ACN3HL_000514"
     CDS             21773..22591
                     /locus_tag="ACN3HL_000514"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHC8005420.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22608..23315
                     /gene="deoD"
                     /locus_tag="ACN3HL_000515"
     CDS             22608..23315
                     /gene="deoD"
                     /locus_tag="ACN3HL_000515"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHC8005421.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23613..24299)
                     /gene="gpmA"
                     /locus_tag="ACN3HL_000516"
     CDS             complement(23613..24299)
                     /gene="gpmA"
                     /locus_tag="ACN3HL_000516"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HHC8005422.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24471..25052)
                     /locus_tag="ACN3HL_000517"
     CDS             complement(24471..25052)
                     /locus_tag="ACN3HL_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8005423.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25185..25868)
                     /gene="rpiA"
                     /locus_tag="ACN3HL_000518"
     CDS             complement(25185..25868)
                     /gene="rpiA"
                     /locus_tag="ACN3HL_000518"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HHC8005424.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26187..26600
                     /gene="rpsL"
                     /locus_tag="ACN3HL_000519"
     CDS             26187..26600
                     /gene="rpsL"
                     /locus_tag="ACN3HL_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HHC8005425.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26684..27154
                     /gene="rpsG"
                     /locus_tag="ACN3HL_000520"
     CDS             26684..27154
                     /gene="rpsG"
                     /locus_tag="ACN3HL_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HHC8005426.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27248..29335
                     /gene="fusA"
                     /locus_tag="ACN3HL_000521"
     CDS             27248..29335
                     /gene="fusA"
                     /locus_tag="ACN3HL_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HHC8005427.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29507..30694
                     /gene="tuf"
                     /locus_tag="ACN3HL_000522"
     CDS             29507..30694
                     /gene="tuf"
                     /locus_tag="ACN3HL_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HHC8005428.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31101..31409
                     /gene="rpsJ"
                     /locus_tag="ACN3HL_000523"
     CDS             31101..31409
                     /gene="rpsJ"
                     /locus_tag="ACN3HL_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HHC8005429.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31440..32069
                     /gene="rplC"
                     /locus_tag="ACN3HL_000524"
     CDS             31440..32069
                     /gene="rplC"
                     /locus_tag="ACN3HL_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HHC8005430.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32097..32720
                     /gene="rplD"
                     /locus_tag="ACN3HL_000525"
     CDS             32097..32720
                     /gene="rplD"
                     /locus_tag="ACN3HL_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HHC8005431.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32720..33010
                     /gene="rplW"
                     /locus_tag="ACN3HL_000526"
     CDS             32720..33010
                     /gene="rplW"
                     /locus_tag="ACN3HL_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HHC8005432.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33049..33882
                     /gene="rplB"
                     /locus_tag="ACN3HL_000527"
     CDS             33049..33882
                     /gene="rplB"
                     /locus_tag="ACN3HL_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HHC8005433.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33925..34203
                     /gene="rpsS"
                     /locus_tag="ACN3HL_000528"
     CDS             33925..34203
                     /gene="rpsS"
                     /locus_tag="ACN3HL_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HHC8005434.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34226..34573
                     /gene="rplV"
                     /locus_tag="ACN3HL_000529"
     CDS             34226..34573
                     /gene="rplV"
                     /locus_tag="ACN3HL_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HHC8005435.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34587..35243
                     /gene="rpsC"
                     /locus_tag="ACN3HL_000530"
     CDS             34587..35243
                     /gene="rpsC"
                     /locus_tag="ACN3HL_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HHC8005436.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35246..35680
                     /gene="rplP"
                     /locus_tag="ACN3HL_000531"
     CDS             35246..35680
                     /gene="rplP"
                     /locus_tag="ACN3HL_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HHC8005437.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35670..35858
                     /gene="rpmC"
                     /locus_tag="ACN3HL_000532"
     CDS             35670..35858
                     /gene="rpmC"
                     /locus_tag="ACN3HL_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HHC8005438.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35883..36149
                     /gene="rpsQ"
                     /locus_tag="ACN3HL_000533"
     CDS             35883..36149
                     /gene="rpsQ"
                     /locus_tag="ACN3HL_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HHC8005439.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36207..36575
                     /gene="rplN"
                     /locus_tag="ACN3HL_000534"
     CDS             36207..36575
                     /gene="rplN"
                     /locus_tag="ACN3HL_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HHC8005440.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36612..36920
                     /gene="rplX"
                     /locus_tag="ACN3HL_000535"
     CDS             36612..36920
                     /gene="rplX"
                     /locus_tag="ACN3HL_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HHC8005441.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36948..37487
                     /gene="rplE"
                     /locus_tag="ACN3HL_000536"
     CDS             36948..37487
                     /gene="rplE"
                     /locus_tag="ACN3HL_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HHC8005442.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37506..37691
                     /locus_tag="ACN3HL_000537"
     CDS             37506..37691
                     /locus_tag="ACN3HL_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HHC8005443.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37727..38125
                     /gene="rpsH"
                     /locus_tag="ACN3HL_000538"
     CDS             37727..38125
                     /gene="rpsH"
                     /locus_tag="ACN3HL_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HHC8005444.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38157..38693
                     /gene="rplF"
                     /locus_tag="ACN3HL_000539"
     CDS             38157..38693
                     /gene="rplF"
                     /locus_tag="ACN3HL_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HHC8005445.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38854..39210
                     /gene="rplR"
                     /locus_tag="ACN3HL_000540"
     CDS             38854..39210
                     /gene="rplR"
                     /locus_tag="ACN3HL_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HHC8005446.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39231..39731
                     /gene="rpsE"
                     /locus_tag="ACN3HL_000541"
     CDS             39231..39731
                     /gene="rpsE"
                     /locus_tag="ACN3HL_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HHC8005447.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39746..39925
                     /gene="rpmD"
                     /locus_tag="ACN3HL_000542"
     CDS             39746..39925
                     /gene="rpmD"
                     /locus_tag="ACN3HL_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HHC8005448.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39969..40409
                     /gene="rplO"
                     /locus_tag="ACN3HL_000543"
     CDS             39969..40409
                     /gene="rplO"
                     /locus_tag="ACN3HL_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HHC8005449.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40409..41704
                     /gene="secY"
                     /locus_tag="ACN3HL_000544"
     CDS             40409..41704
                     /gene="secY"
                     /locus_tag="ACN3HL_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HHC8005450.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41766..42413
                     /locus_tag="ACN3HL_000545"
     CDS             41766..42413
                     /locus_tag="ACN3HL_000545"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HHC8005451.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42604..42822
                     /gene="infA"
                     /locus_tag="ACN3HL_000546"
     CDS             42604..42822
                     /gene="infA"
                     /locus_tag="ACN3HL_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HHC8005452.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42855..42971
                     /gene="rpmJ"
                     /locus_tag="ACN3HL_000547"
     CDS             42855..42971
                     /gene="rpmJ"
                     /locus_tag="ACN3HL_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HHC8005453.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42989..43354
                     /gene="rpsM"
                     /locus_tag="ACN3HL_000548"
     CDS             42989..43354
                     /gene="rpsM"
                     /locus_tag="ACN3HL_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HHC8005454.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43382..43771
                     /gene="rpsK"
                     /locus_tag="ACN3HL_000549"
     CDS             43382..43771
                     /gene="rpsK"
                     /locus_tag="ACN3HL_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HHC8005455.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43851..44789
                     /locus_tag="ACN3HL_000550"
     CDS             43851..44789
                     /locus_tag="ACN3HL_000550"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HHC8005456.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44817..45197
                     /gene="rplQ"
                     /locus_tag="ACN3HL_000551"
     CDS             44817..45197
                     /gene="rplQ"
                     /locus_tag="ACN3HL_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HHC8005457.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45469..46308
                     /locus_tag="ACN3HL_000552"
     CDS             45469..46308
                     /locus_tag="ACN3HL_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HHC8005458.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46284..47153
                     /locus_tag="ACN3HL_000553"
     CDS             46284..47153
                     /locus_tag="ACN3HL_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HHC8005459.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47143..47940
                     /locus_tag="ACN3HL_000554"
     CDS             47143..47940
                     /locus_tag="ACN3HL_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HHC8005460.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48143..48889
                     /gene="truA"
                     /locus_tag="ACN3HL_000555"
     CDS             48143..48889
                     /gene="truA"
                     /locus_tag="ACN3HL_000555"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HHC8005461.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49222..51891)
                     /locus_tag="ACN3HL_000556"
     CDS             complement(49222..51891)
                     /locus_tag="ACN3HL_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HHC8005462.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52129..52317)
                     /gene="rpmB"
                     /locus_tag="ACN3HL_000557"
     CDS             complement(52129..52317)
                     /gene="rpmB"
                     /locus_tag="ACN3HL_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HHC8005463.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52587..52949
                     /locus_tag="ACN3HL_000558"
     CDS             52587..52949
                     /locus_tag="ACN3HL_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHC8005464.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53001..54683
                     /locus_tag="ACN3HL_000559"
     CDS             53001..54683
                     /locus_tag="ACN3HL_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HHC8005465.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54800..56836
                     /gene="recG"
                     /locus_tag="ACN3HL_000560"
     CDS             54800..56836
                     /gene="recG"
                     /locus_tag="ACN3HL_000560"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HHC8005466.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            56885..57886
                     /gene="plsX"
                     /locus_tag="ACN3HL_000561"
     CDS             56885..57886
                     /gene="plsX"
                     /locus_tag="ACN3HL_000561"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HHC8005467.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58008..58250
                     /gene="acpP"
                     /locus_tag="ACN3HL_000562"
     CDS             58008..58250
                     /gene="acpP"
                     /locus_tag="ACN3HL_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHC8005468.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58518..59522
                     /locus_tag="ACN3HL_000563"
     CDS             58518..59522
                     /locus_tag="ACN3HL_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005469.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59523..60467
                     /locus_tag="ACN3HL_000564"
     CDS             59523..60467
                     /locus_tag="ACN3HL_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005470.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60467..61429
                     /gene="opp4B"
                     /locus_tag="ACN3HL_000565"
     CDS             60467..61429
                     /gene="opp4B"
                     /locus_tag="ACN3HL_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HHC8005471.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61456..62370
                     /locus_tag="ACN3HL_000566"
     CDS             61456..62370
                     /locus_tag="ACN3HL_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005472.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62396..64177
                     /locus_tag="ACN3HL_000567"
     CDS             62396..64177
                     /locus_tag="ACN3HL_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8005473.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64525..65211
                     /gene="rnc"
                     /locus_tag="ACN3HL_000568"
     CDS             64525..65211
                     /gene="rnc"
                     /locus_tag="ACN3HL_000568"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HHC8005474.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65231..68812
                     /gene="smc"
                     /locus_tag="ACN3HL_000569"
     CDS             65231..68812
                     /gene="smc"
                     /locus_tag="ACN3HL_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HHC8005475.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            68821..69630
                     /locus_tag="ACN3HL_000570"
     CDS             68821..69630
                     /locus_tag="ACN3HL_000570"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8005476.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69641..70639
                     /gene="ftsY"
                     /locus_tag="ACN3HL_000571"
     CDS             69641..70639
                     /gene="ftsY"
                     /locus_tag="ACN3HL_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HHC8005477.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            70826..73093
                     /gene="gshAB"
                     /locus_tag="ACN3HL_000572"
     CDS             70826..73093
                     /gene="gshAB"
                     /locus_tag="ACN3HL_000572"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HHC8005478.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73182..73634)
                     /locus_tag="ACN3HL_000573"
     CDS             complement(73182..73634)
                     /locus_tag="ACN3HL_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HHC8005479.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            73784..74734
                     /locus_tag="ACN3HL_000574"
     CDS             73784..74734
                     /locus_tag="ACN3HL_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HHC8005480.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            74727..75686
                     /locus_tag="ACN3HL_000575"
     CDS             74727..75686
                     /locus_tag="ACN3HL_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HHC8005481.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            75683..76438
                     /locus_tag="ACN3HL_000576"
     CDS             75683..76438
                     /locus_tag="ACN3HL_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005482.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            76461..77414
                     /locus_tag="ACN3HL_000577"
     CDS             76461..77414
                     /locus_tag="ACN3HL_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8005483.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78058..78354)
                     /locus_tag="ACN3HL_000578"
     CDS             complement(78058..78354)
                     /locus_tag="ACN3HL_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HHC8005484.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            78709..79065
                     /locus_tag="ACN3HL_000579"
     CDS             78709..79065
                     /locus_tag="ACN3HL_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HHC8005485.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            79075..79974
                     /locus_tag="ACN3HL_000580"
     CDS             79075..79974
                     /locus_tag="ACN3HL_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHC8005486.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        26220 a        14426 c        17052 g        22478 t
ORIGIN      
        1 gtgaaaatgt aaacctaaat gagtatcaaa ttgcaactga atttgatact cgttttttat
       61 tgttaaatca acgtttgttg ttaatttaca ccacaaaatg taagttaaaa tgtatataaa
      121 aatgcgaacg tgaaataatt attgtaggaa tgcaaattgg tgtgttaaaa tggttacaat
      181 ttactaagca aaaaggggtg cattttccta tgcaatttct tgagccaaaa aataagaacg
      241 ctaagtctgt ggattgggaa atatcagagc aagtaagggt gatagttaag caatacgctg
      301 aatatgcaga gcgtactgaa agcgaagcag tggatgaatt cttattgaac attttagacg
      361 ataagaagtt tattgaatgg attgccaaca agcgaagtaa taagcggatt gttgaaaaaa
      421 tgggtatcaa agatagagtg ggttgataga caatgaccaa gcttaaaaga ttagccacga
      481 aggaagatga aattgtagat gttaaaattc cgatttcaaa cgaagaatta aaagataggg
      541 ctaaacaata tgatttatta actccaaaac gatttgcaac aaggtataac aaaatgttgt
      601 tcttgccaac gtcttttaaa tggaacggtt ctgaatatcc cattcaatat aattactgca
      661 tcaatccgtt ttgttgtaat tttgggaaag aacagcacaa attcaaagat gtaaaaggga
      721 aaccaagtcg atataaaatg actggtagtt ccaaagataa aggtcataaa ggtatgtact
      781 gcaatgacaa tcctattggc agaggtgtat cgcaaaactg tacagtaacc cctttatcta
      841 attggtctgt tgttgaagaa attaaacgcc ttatagaaat caatagcatc caagatgttg
      901 agccagatta tcaatttcat aaagaaggct gctcggaaga agaatcaacc ccattcaatg
      961 agccgaagca attttacaaa agggggaaaa gtaggggcaa atctcaacgc tatcaatgta
     1021 aggcgtgtaa gaagttcact aatgttctac caaaaagaga agaaaccact acttatcacc
     1081 aacaaaagaa caccattctt ccaatgttcg ctaagatggt tgttggaagg gtttcagtca
     1141 gtcgtacttg tgatatttta ggaattggag ttggaaccta ctatcataag ctggagtggc
     1201 tgtataggcg ttgtttggag tttttagaac gatatgagac acaacccctt caaacaaaga
     1261 aatttaacga gatgtggctt aatacggaca agatgcacta ctacctaaat aacgtccgta
     1321 agaaaggaca aggttcaaag aaatatacgg ggtttgaaga ccttaatatg caaacgtata
     1381 tagttgtatc tgctgaggtc ttatcaagat atgtgttccg ttctgatgtt gcctatgatt
     1441 ggaatatttc aatggatgaa ttaaatgaag atacaagaaa attcaaagaa gaccatctca
     1501 atacttttag tcgtaaaaat gataggttag attggtctta ttatccacaa gaaccatccg
     1561 ctaacgatag cgaaaatagg aatgcttatc ttcacgaatt agggaaaatt actaatagga
     1621 gtagatttgt cgatggttta aatgttgatg ctccttatac tacaactgct cactattggt
     1681 taattaaaca aatggttaat gccgacgaat ggcgaatgat tagtgatgat gacttctcta
     1741 ttagaaacgc cttttataga gtattcacga aagaattaag gttgagcgat gcacatcatt
     1801 ttatttgcca agttaacaag acgaaaagca gaaaacaatg cttaaaagaa ttcggacaag
     1861 caaaagcaga actgctcgat tggggagata tcagaggatt caaaacaaag tttctacgga
     1921 ctttggcatc tcattatcta actgaattac taacaagtca tcaattccac gaagaggcta
     1981 ttagtaaaga tggagaaaga tatcgcaaat atgccgataa ccctatcaaa catccattag
     2041 ccactaagga taaaggattt tattcagttg attgtagaac ggatttatct gctctggaac
     2101 caaacgaaat cgcaaagatg ctattaaatg ttaatgacca ttcgaccaat agctttattc
     2161 aacagataag acgttatata tcatctcttg aaagaccatt aacaacagct cgtggtgata
     2221 agaagagcta tatttacgct aacttcaatc cgaagtatgc tcaatttgcg attacaattc
     2281 taagaactta ctacaacttt tgtcgccctt ttaaatcagc ggataaaaag gttttgacac
     2341 ctgctcaaag attagggatt acagataaac aatttgattg gaaagatata atttatttca
     2401 aatgacaaaa agagcttgga gtaatcccaa gctcttgtgc tttatcttta ctgttcttct
     2461 tcaattaacg cacccgttaa ctcaataagt tttttctttc atatacatga aaatagtagt
     2521 tatacggatt tttatcattc tttatccctt tttgggcaaa tacctcattc cattcctcat
     2581 aattcacttc tggaaaaaaa gtatctcctt cgaattcatg atgtattttt gtgatgtaca
     2641 ttttctcaac ataagggaaa aacaaattat aaatctgttc tcctccgaaa ataaaaattt
     2701 cttcttcgtt tttacataac tcaaaaacat cttctattga atgaacaatt tcacaaccat
     2761 taaaggtaaa ccccttatct ctcgtcagaa taatatttct tctgtcaggt aaggctcttc
     2821 cgattgattc aaggttcttc ctacctaata ttatcggatg tccctttgta gtatttttaa
     2881 catattccca gtccttggga atcctccaag gaatgtcatt ctctttgcca atcactctat
     2941 tcttatccat cgcagcaatc aaagaaactt tcatttataa cacagccttt ttaactaatt
     3001 taccatctaa tttcttattt ctatcaaaaa accttttctc attatcctgc ccgttagttg
     3061 aataagcaat tttttctata agttatatta tcataatacc acaaaatcac aaattttcat
     3121 tcaattatca ttttcaattg cattttataa atcattttgt atgtaatttg gtatgtaagt
     3181 taaaatgaaa aaagtagtcc attttgaagt acattttgtc attttgtact ccaaaactga
     3241 actacttact tgcatatata cgcctttata gtggagtact acatttacga gattcggtta
     3301 gagtatcaga aaaagaaaaa ataaaagtta cagaaatgta tacttcaata aatggtgaat
     3361 tatgtaagat tgatagagct tattctggag aaattgttat tttgcaaaat gagtttttga
     3421 agttaaatag tgttcttgga gatacaaaac tattgccaca gagaaaaaag attgaaaatc
     3481 cgcaccctct actacaaaca actgttgaac cgagtaaacc tgaacagaga gaaatgttgc
     3541 ttgatgccct tttggaaatc tcagatagtg atccgcttct acgatattac gtggattcta
     3601 cgacacatga aattatactt tctttcttag ggaaagtaca aatggaagtg attagtgcac
     3661 tgttgcaaga aaagtatcat gtggagatag aactaaaaga gcctacagtc atttatatgg
     3721 agagaccgtt aaaaaatgca gaatatacca ttcacatcga agtgccgcca aatcctttct
     3781 gggcttccat tggtttatct gtatcaccgc ttccgttggg aagtggaatg cagtatgaga
     3841 gctcggtttc tcttggatac ttaaatcaat catttcaaaa tgcagttatg gaagggatac
     3901 gctatggttg cgaacaagga ttatatggtt ggaatgtgac ggattgtaaa atctgtttta
     3961 agtacggttt atactatagc cctgttagta ctccagcaga ttttcggatg cttactccta
     4021 ttgtactgga gcaagccttt agaaaagctg gaacagaatt gttagagcca tatcttagtt
     4081 ttaaagttta tgcaccacag gaatatcttt cacgggcata taacgatgct cccaaatatt
     4141 gtgcaaatat cgtaaatact caactgaaaa ataatgaggt cattattatt ggagaaattc
     4201 ctgctcgatg tattcaagat tatcgcaatg atttaacttt ttttacaaat gggcttagtg
     4261 tttgtttagc agagctaaaa ggatatcagg ttaccactgg cgaacctgtt tgccagaccc
     4321 gtcgtctaaa tagtcggata gataaagtaa gatatatgtt caataaaata acttagtgcg
     4381 ttttatgttg ttatataaat atggtttctt attaaataag atgaaatatt ctttaatata
     4441 gatttgaatt aaagtggaaa ggaggagatt gttattataa actacaagtg gatattgtgt
     4501 cctatttgtg gaaataaaac aagactacga atacgagtgg atactatact taaaaatttc
     4561 cctttatact gccccaaatg taagaacgaa actttaatta atgttcaaaa aatgaatata
     4621 ataacaatca aagagccaga cgccaagacg cagagccgat aatttgagaa atgaaactct
     4681 catcttatcg gctctttttg tttatctgaa ttttactgac tagccttcaa tatttcttgc
     4741 ttcattgata ccttttgcta gtgcttccat taaggatagt tctttgtctg taaagctatc
     4801 catgtatttt tctacctgta accttcgagt gcttttaatc aaattatctg taggtaagaa
     4861 aaattcatca atagatacat ggagtaatga tacaagatca tacagcactt gtgtacttgg
     4921 gtgttgtcct ttgttttcta tatttgttaa ataacgtggg tcaatttcaa tcattgttcc
     4981 cacttgttca cgagtgagac cccgtttcat tcgagcctct ttaatcgcta aaccaacggc
     5041 tctaaaatcg tatttatctt cttttttacg catactaaat cacctctata cattttactg
     5101 ttcctatata accataaaca ggtatagaaa aacatgttat atagtttatg agttcctata
     5161 gaacactgtg gaatttatta atgcgatgaa tccaatttca aatagaaagg tcgctgattt
     5221 tatttaccta tacaacttta taaaatttag tcatactcct agaaagtaga taaaattggc
     5281 gacttaatgg agggaaaagt cgccatgaga aagataatct gtcatctagt tctcttaatt
     5341 aagttcttat caaaaaaact tatccacctg tactggatag atatgaccat caatgtggtt
     5401 ttgcagatta catagataga aaaatcaaag catatgaaca gagaaaacaa tctgtttatg
     5461 tgcttttttg gtcacttaat aaatatcttt taggatttct cttcatttat gcaacaaatc
     5521 ccccgttcgt gtcggggttt agtatgaagg gagataaaga agcacatgcc actccctttc
     5581 acgacagaaa gggggtgaaa agcatgaaac catcttcttt tcaagaaacc atagaaaatc
     5641 agtttgacta tatctgcaaa caagttattg aagatgaacg aaaagattac ttcaaacatc
     5701 tagacagact atcagcaaaa gaagtctcgt tttctgatat agataactac cttgtcaact
     5761 ctttttctac tgttgatacg tacgtcactg atttccaact atttaaatta tttggattaa
     5821 gaatcaatgt tgaaagtgat ttattaagtg aagccctgcg tcatctttca gagaaaaaac
     5881 ggaacattat tttacttcat tactttatgg atatgagtga tgtggagatt gcggagttac
     5941 taaatttgaa tcgttcgact gtttatcgtc atcgaataag tggactagcc atgattaaag
     6001 aattcatgaa ggagtgtaaa gaatgaaaac agcttatcca agggttccct tccccctcat
     6061 tgtaaaggcg acagatggcg acgtggaagc aattaatcag attgttaaac attatcgagg
     6121 gtatacctca aaacgttcat tacgtcgcat gacagacgaa tatggaaatt ctcatatggt
     6181 tattgatgaa accctacgtg gcagaatgga aacgaaactc atctctaaga ttttatcgtt
     6241 cgaaattaaa tagtcccatt ttttcgtgga agcgtgtcga atcgtatcca cgcttcccga
     6301 tttgggaggt ttgttattcc atcaaagcat attgtgtgtt cagtaggttt tgataggcta
     6361 acaagccaaa cgttctttga caaccaaata aaggcaatcg aatacgtttc ggtaagaaaa
     6421 gagctgatga actaacacgc catgacctac aaaattagtg agcgattcat gttagtaatt
     6481 cgaaagtaat ctttagcagg attgctgcca tgactttctt atcgtgataa tgatactccc
     6541 gtatagccat agtccgagcg ttagaagcgt cacaggcaat gggtacggct acatgagaac
     6601 catgcagaag tgaaattcct gtgagctttg ctagagctgt tcgattgcta agatattctt
     6661 ctcttgtcag tgtattatta taaaactatt tgatataatt ataggtgaat attggagttt
     6721 tcctagccta taattgggaa aggagtaata atgataacgg tcacaaaaaa ggatttagtt
     6781 gagctaggat atggaacttc tttttcagca gacatcataa aaaaagcaaa agaattgatg
     6841 attacaaaag ggcatatcta ctatcaatct cgaaagctag atagagtccc tcgtgaagct
     6901 gttgaagaaa ttctaggaat tcggttttca aatgaaaaca ggtctgagta gtttttgcac
     6961 agtaaggagt aaaaactatg gttaaagacc caataaaaaa agcaaagaat ggaacctatt
     7021 attttcgtgc aaatctaggt tatgattcta aagggaaaaa aattcaaaaa tatcgtagtg
     7081 gattcactac taaaaaagaa gcaagagaag aatattcgaa actgctattg atgaaaccag
     7141 aagaattaag tgagaataag gataaaatga cgtttaaaca ttatatcttt gaaattttcc
     7201 ttccatggta taagacacag gtaaagctca gaacatatga aaatcgctta ccaactatta
     7261 agaagcattt ctcttatttt gataaaatgg ctgtttccga tattgagcct attgatgtgc
     7321 aaaattggca actaaaatta tcaaagaagt gtaagtcttc ttatgtaaga gctgttcaag
     7381 gactattttc agttgctatg gatcgagcaa ttgtccttgg gataaccacc acaaatccat
     7441 ctaagattat tggcaatgtg aaaaagcaaa agtctaaaat tgaattttgg acaaaagaag
     7501 aatttgaaaa agtaatctct ctaatttaca aagaagatta ctatcaacac tttttattta
     7561 tctctctgtg gtttttattt atgactggaa tgcgaattgg tgaagctact gccattcaat
     7621 gggaagatat tgattttgac tcaggagtac taaccatcaa caaaacactc tattacaaga
     7681 atcaatcgaa ttatagattt gttgaaccaa aaacaaaggc gagcgttcgt catattgtat
     7741 tagataaatg cacattaact tatttatccg aatggaagga agtacaacaa aatctaattc
     7801 agacagactt tgtaatgagc tataacggta ttcctaccca aaaacataca ctatcatatg
     7861 ctattgaacg ctatgctaag ctggctggta tccatcgaat cagaatccat gggttacggc
     7921 attctcatgc ttccttgtta atcagtatgg gagaaaatcc acttatcatt aaagatcgtc
     7981 taggacacga agatattgag acgactttag gaacgtatgg acatctttat cctaacagta
     8041 atttcgaggt agctaacaaa ttaaatggag ccatttcctt taaagaagca aaacaaaatt
     8101 atgatacttc accaaagaat caatttactg tagactactt gcgaaacaaa gaaatgaaaa
     8161 aagtgcaata aaagtgcagt aaaaagataa gaagagccag aaacccttgg tataagagga
     8221 tttctagctc tcctacaact attcccactc cactgttgct ggtggtttag aagtgatgtc
     8281 atacacgata cggttgacgt gggctacttc gtttacgata cgtacagaga ttttttgcaa
     8341 gacttcccat gggatacggg caaagtcagc ggtcattccg tcgattgaag ttacagcacg
     8401 gataccgact gtgtagtcgt aagtacgtcc gtcacccata acaccgacag agcggatccc
     8461 tggaagaaca gtgaaatatt gccagatatc acggtcaagt ccagcagctg cgatttcttc
     8521 acgcaagata gcatcagatt cgcgtacgat ttctagcttg tcttcagtga tttcgccaag
     8581 aacacgaata ccaagaccag gaccagggaa tggctgacgc caaacgattg aatcaggcat
     8641 gcctaactga gtccctaatt cacggacttc gtctttgaat aatgtgttta atggttcgat
     8701 caattcaaat tgcatatctt ctggcagtcc acctacatta tggtgagatt tgatcgtctg
     8761 tgctgtttct gtaccagatt cgataacgtc agtatacaac gttccttgtg ctaggaaaga
     8821 gacgccttct tcaccagcaa gttttgttgc ttcgtcatca aaaacatata cgaattcatt
     8881 cccaatgatt ttacgttttt gttctgggtc agatacacct ttcaacttgt ctaagaagcg
     8941 atctcttgca tcgactttga tgatgttcaa gccgaatttt ccgcctagac tttccattac
     9001 ttgttccgct tcgcctttgc gtagcagacc gtggtcaaca aagatagatg tcaattggtc
     9061 accgatcgct ttttgtaaaa gaaccccaac gacactagaa tcaacgccac ctgaaagacc
     9121 aagcaagact tttttgtcac caacttgttc acggattttt tctacttgca tatcgataaa
     9181 gttatccatt gtccagttac cttcacagtg acaaacatca aaggcaaagt ggcgcagcaa
     9241 ttcgattccg tattcggaat gacgtacttc tgcatggaat tggataccat aaaaattacg
     9301 tgttgtgtct tggatagaag caatcggaca atctttgctt gttccgactg tttcaaagcc
     9361 ttcaggaact ttagttacca agtcaccatg gctcatccat actgtttgtt gttttggtgt
     9421 ttctttaaac aagacagctt gatcgcttgt tacttctaac aaggctttcc catattcgcg
     9481 gtttttagca ggctctacgg aaccgccaag tttgtacgtg atcaattgca taccatagca
     9541 aatccctaat acaggaatac ctaaattgaa gatctcagga tcgatcccaa atgcattctc
     9601 atcatataca ctgtttggtc cgccagaaag aatgattccc tttggattca tcgcttttac
     9661 ttcttctgca gtaatgcggt ggctcaataa ttcggaaaag actccaagat cacgaatacg
     9721 tcttgtgatc aattggttat actgactacc gtagtctaat acgataatct tttcaacgtt
     9781 cgtcatatcg gcaacgtttg tcaaatttat tacccctatc cctttaaatt ttatctcaaa
     9841 atagtcaaac tattttaaaa tgctaatatt ttcgcatgaa aatcgaatcg atgatatgat
     9901 tttcagtttt atggagaatt atatcggctc ttcctcgtgt aggcaagata tattcctgta
     9961 aatttttcaa attcacattt ttccatacat cttttgccat tttaaaggct tcttcacgat
    10021 ctccgatagc aaaacgataa taataattct ctggattttg gaaagccgta tccagtaacg
    10081 caccaaaacg atccaaatac catttttcga tcagcacggg atcggcatcg acatagacag
    10141 aaaaatcaaa aaagtcgctg acgtagattt gctgattcgc aggtaattga agcgtattga
    10201 tcccctcaac gatcaagata tcaggctgct ggatcaattc gtacttgtct ggaatgatat
    10261 catacacatc atgtgagtaa acaggtactt ttatctcttc ctgaccagat tttacacggt
    10321 tcaagaaatc gatcagcatc tccatatcat aactttcagg aaatccttta cggtccatga
    10381 ttccacgctc ttttaatata cgatttggat aaagaaatcc gtcagtcgtg atcagctgaa
    10441 cgtttcttcg tttgaaggta cgagacaaaa tcgtctgcag cagtctggct gttgtacttt
    10501 ttccaacggc tacacttccg gcgatcccga taataaaagg cggtacttct acgtatttat
    10561 gaagaaataa acctttactc aagaacaaag attcaaattc tttcatataa agataaatca
    10621 gatgagcaag aggtacatag atatctcgaa catcctgcat ggaaatgcgg tcattcaaac
    10681 ttttgatatt atctagttca tcttgtgtca aaggtgcttg cccattacga taaaattctc
    10741 gccattcttc tcttgccaca cggtagtagt tcattggatc attcatatta gcctcctgcg
    10801 ttctcccatc aatggaacta ttttaacaca aaataaacgc aaaccccacc acttaagaga
    10861 gattgccgat ctttttgtat aatctttata atagaaagaa acggagtctt attcttgact
    10921 tgcgcacgga tacataaaag gatagactgt tgtcatgaaa gaaatgagaa ggatggaaga
    10981 catgacaaat cattactatt ctgaacgccc agatacggcg cacgattttg aacaatgggc
    11041 ttttgagtta aaaggcagaa cctttcaatt tgtaacagat tctggtgtat tttcacgtga
    11101 aacagtggat tatggttcac gtgtcctgat tgatgctttc gattgggaag agttacctga
    11161 tgaaggaaag atcttagatg tgggatgcgg gtatggaccg attgggttag ctttggcatt
    11221 tgcgacacag cggtttgttg aaatggtcga cattaatgaa cgagcggtaa gtctagcgca
    11281 aggaaacgca aagcgtaacc aaatcgaaca tgttgatatc catcaatcga atatctatga
    11341 agcagttcat gaagaaacct atgcagctat cgtaagcaat ccgccgatcc gtgctggaaa
    11401 aaaagttgta catgaaattt tgacaggcgc atatcctcgg ttgaagaagg gcggtacact
    11461 gacaattgtg atccagaaga aacaaggagc gccgagtgcg caaaagaaaa tggaagaaac
    11521 atttggtaat gcagaaatcg tcacaaaaga taaaggatat tatatcatca aaagtgtgaa
    11581 agaataacta gctgaaaaat agtggagcga cgaaagagtg gaactgggcg tgcatgtacg
    11641 ggtacgtatc agttcttttt ttgttgagaa gtttttaaaa acaaagaact attttttctt
    11701 caaaaagaaa tagtaggaac agagtcgttg ttttttacga taaaataaat aagatacaga
    11761 acttgtatag aaggctgcca agtcggtaga taaaggaggt ttttatcaaa aaacatactt
    11821 tccttttttc tctattcttt tcttgggggt tttggtacac tgatagggaa tttagataga
    11881 agggagccaa taggatgaag ctgaccatca gagatatcgc agaaatggca ggcgtatcag
    11941 taacaactgt ctcacagatt ttgaataaca aaggaagcag atttagtgat aagacaagaa
    12001 aaaaagtgtt gtcgatcgtg aatgaacatc attataagcc cgattatttc gcttcaaatg
    12061 tgatcaatcg acattcaaag accatcggaa tgatcgtccc tgatgtcact gatttcttct
    12121 tctccaaact gatcgaaggt gtagagagct atttgaatcc tttgggctat gtgatcatgt
    12181 tatgcaattc tcgtcatagc caagaaaatg agatcaagta tttacaagag ctttcccacc
    12241 gctcagtgga cggaatcttg ctggccacac caaatatttt acctgagaaa tatgcattag
    12301 acagcggttt ttatcaaaaa atgccaatca ttttaatcga tcgcggattg aatcgtcggg
    12361 ataacggacg gcttatcgta aaggaatatg agggcgccta tcaagctgtt tcgctgttta
    12421 ttgaaaatgg ccatacgaag atcggcatgc tgaaggaaac cactggatac tatcaattag
    12481 aagaacgttt caacggatat cgtcatgcgc tgaaagatca tggcctgcct tttaatggga
    12541 aatttgttga acatggagag ttgactgtcc aaggtggata tactgcatca aaaaaattac
    12601 tcaaacataa agatatcacg gctatttttt gcgggaatga tgccatggcg atcggatgct
    12661 atcaggcgat cgatgaattg ggcaaaaaaa tcccagaaga tatctcagtc ataggattcg
    12721 atggattaaa gctgtcagaa tacatgattc cgcaattgac gacagtgcag cagccaagtt
    12781 ttgatattgg attttatgct gcacgtttcc tgatcgatac gatcgaattt cctcaaagaa
    12841 aagttccgaa caaagtgttc gaaacaaaat taattattcg tgagagcgta aaagtattga
    12901 caaagggcta actcggcggt atattgctta tgtaagcatt tacaaaggct agttagtgct
    12961 ttttttattt ttagtaaacc agtttactaa agtggtttac ctttcctaaa aataatgtat
    13021 aataccgaat gaagacaagg aggatcaggc aatgcgaatg gtggatctga ttgaaaaaaa
    13081 gagggatgga aacgagctgt cgaaagagga aatcgagtac atcgtcacga actatacgaa
    13141 tggaaagatt ccagattatc aagtcagtgc attattgatg gcaatttttt atcaagacat
    13201 gacaaatgaa gaaatcacga acttaacatt ggcgattgct aattctggtg atgtcatcga
    13261 tttgagttct cttgaaggaa taaaggtaga taagcattcg acaggtggcg ttggtgacac
    13321 gaccacattg attttagccc ccctagtagc tagtgtcgga gtgacagtgg ctaaaatgtc
    13381 tggacgcggt ctaggttaca caggtggtac actagacaag ctagaagcaa ttcccggatt
    13441 tcagatcgag ctttcggatg aagaatttgt acgcattgtt aatgaaagta aagtagcggt
    13501 aattggtcaa tcaggaaact tggcaccggc ggacaaaaaa ttgtatgcct tgcgtgacgt
    13561 cacagcgacc gttgattctc ttccgctgat tgccagttcg attatgagta aaaaaatcgc
    13621 ggcaggagca gatgcaatcg ttttggatgt gaccactgga gacggtgctt tcatgaagaa
    13681 catcgaagat gcaagacgtc tggcaaagac catgacgagc attgggaaac tggctaaccg
    13741 agaaacagtg gcggttatct cagatatgtc agaacctctt ggcgaagcta tcggaaatag
    13801 tctagaagtt gtcgaggcaa tcgaaacatt acaaggaaat ggtccagaag atctagtaga
    13861 aatgtgctac gccttaggaa gccaaatggt tgttcttgct ggcaaagcta agacaaccga
    13921 tgaagcaaga acgttgcttc aagaagctct ggaatcaggt aaagcgttag caaaattcaa
    13981 agaaatgatc caaaatcaag ggggagaccc agcgatcgtg gaacatccag aacgaatttt
    14041 gactgcacgc tacacaatgg agcttcctgc taaacaaagc ggagttgtgt caaaaatcgt
    14101 ggcaaatgaa ttaggaattg ctgcaatgat gctaggtgct gggcgtaaaa ccaaagaaga
    14161 agatattgat cacgctgttg gattgaaact gcataaaaaa attggtgaca ctgtgacaaa
    14221 aggtgagtca ctattgacga tctatagtaa cgacgaagaa atcacttctg tcattgaatt
    14281 attatataaa aatattgaaa ttggtgaatc ggcaatgaag ccaacgttga ttcatgacat
    14341 catcacagaa taaaggaaaa aagcggactt taccgtttta aagaaaaggg gaaaagaaat
    14401 ggaactaaac cgaatgatcg accatactat tttgaaagca gacgcatcta aagaagctgt
    14461 gatgcaaatt atcgaagaag caaaaaaata ccatttttat tctgtctgca tcaatccagc
    14521 atgggttgcg ctagcgaaag aacaattaca aggtgagcca gtagccgtat gtacagtaat
    14581 cgggtttcct ctaggagcaa acacacccga gacaaaagca tttgaaacaa cagatgccat
    14641 caataacggt gcagatgaag tcgatatggt catcaatatc ggtgctttga aatcaaagga
    14701 tgatcaacaa gtccaaaaag atatcgaagc agttgttgaa gcagcaaaag atcgtgcgct
    14761 tgtcaaagtt attattgaaa catcgttatt agatagagaa gaaatcatcc gagcttgcga
    14821 aatagcaaaa gctgcaggcg ctgattttgt caaaacatca actggtttct caacaggcgg
    14881 agcaaaggta gaggatgtcc gtttgatgcg tgaaactgta ggaccagaaa tgggtgtcaa
    14941 agcttccggc ggtatccata acgaagaaga agcaatggca atgatcgaag ctggtgctac
    15001 aagaatcgga acaagcgcag gagtagcaat cgtatctggt tcaactggtg aaggctatta
    15061 attttttcaa aggagaagct catggcagaa ctcaaacaag aatggatcaa cacagctatt
    15121 gaagcgttag ataaagccta tgttccttat tcccattttc cggtaggcgc ttgtctcgta
    15181 acggaatcag gcaagattta tcaaggcatc aacattgaga atgcatcatt tggattaacg
    15241 aattgtgccg agcgcacagc ttttttcaaa gcagtatctg aaggagaaaa aacatttacg
    15301 catctagtcg tagcggggca cacccccgat cctatctctc cttgtggtgc atgtcgacaa
    15361 gtaatggcag aattctgttc ccctgatatg ccggttacgc tagtaggaga caatggtgtg
    15421 acgaaggcaa cgaccgttcg tgcactgctg ccttatgcat ttactgaaaa agatctataa
    15481 ctcatgttca ttcagtcagc tgactgttga aaaataaaac aattatttta ggaggcttta
    15541 cagaaatgaa aaaagcaaaa ttatttggtt taggtgctgt cgcactagca gcagggttat
    15601 ttttaggtgc atgcggcaac aacggctcta ctgattcatc cggtggcaaa agctcatcag
    15661 acacaacaac tgcagcattg atcacagaca caggtggtgt agacgaccgt tcattcaacc
    15721 agtcagcttg ggaaggacta gaaaaatggg ggaaagatca aggactttca cgaggaaatg
    15781 atggcttcca atatttccaa tcttcaaatg aatcagatta catcccaaat attgaccaag
    15841 cattgaatgc tggattcaaa acgatttttg gtattggtta taaactaaaa ccagcgatcc
    15901 aagaacaagc aacaaacaat acaggtacga actttgttat tatcgatgat gtcatcgatg
    15961 gattagataa cgttgtatct gcaactttca aagacaacga agcttcttat cttgcaggtg
    16021 ttgcagcagc ttatacgact gaaacaaacg tagtcggctt tatcggcggt gtaaaaggtg
    16081 aagtaatcga tcgttttgat gctggattca aagccggtgt tgatgcaggt gcgaaagaat
    16141 taggaaaaga aatcaaagta ttgaatcaat atgctggtga cttctctgct ccagataaag
    16201 gacgttcaat tgctcaaggt atgtatgcac aaaacgcaga tatcatcttc catgcttcag
    16261 gcggtacagg taacggtgta ttccaagaag caaaatcatt gaacgaatca ggcgacaaaa
    16321 aagtttgggt tatcggtgtt gaccgcgacc aatcagacga aggcgaatac acattaaacg
    16381 gcgaaaagaa aaacttcaca ttgacatcta cactgaaagc agttggaaca gtagtagaag
    16441 atttggcaca aaaatcagcg gacggtaaat tccctggcgg cgaacacact gtttatggat
    16501 tgaaagaaga cggtgttggt ctaacagaag gacaactttc tgacgaagcg aaaaaagcag
    16561 ttgatgaagc aaaagaaaaa atcatttcag gtgacgtaaa agttccagaa actcctgaag
    16621 aaaactaaaa ccatttctat agccttgtta gacacatgtt tgacaaggct atggtttgat
    16681 tagaacaaga attgttcatt tatccaagct gccttgtgac agtttggata agggaacaac
    16741 tccctgaagt aatgtttgtt tcaaaagaag aacgctcact aagcgtgaat cttagtcaat
    16801 cgttgcccta gatagaaatc gttaggatgt gaaaaaaagg tggttcaaga aaatattgtc
    16861 atagaaatgc agaatattac caaagaattt ggaacattca aggcaaatga caacatcaat
    16921 ttacaagtaa aggcaggaga aattcatgcg ttgcttggag aaaacggtgc tggcaaatct
    16981 acattgatga acgtgctttc cggattatta gagccgacat cagggaaaat tttgatgcgt
    17041 gggaaagaag taaagatcac aagtccgacc aaagccaacc aattagggat tgggatggtc
    17101 catcagcact ttatgcttgt tgatgccttt actgtaacag aaaacatcgt gttgggaagc
    17161 gagcctagtc gcgcagggat gcttgaccat aaaaaagcac gaaaagagat ccaaaaagtt
    17221 tctgaacagt atggattgtc agtcaaccca gatgcttacg ttcgtgatat ttcagttgga
    17281 atggaacaac gggtagaaat tttaaaaaca ctttaccgag gagcagatgt actgattttt
    17341 gatgagccga cagctgtatt gacccctcaa gaaattgatg aattaatcgt gatcatgaag
    17401 gaattagtca aagaaggcaa gtcgatcatt ttgattacgc ataagttaga tgaaatcaaa
    17461 gcagtagctg accgctgtac agttatccgc cgtggaaaag gaatcggtac agtcaacgtt
    17521 aaagacgtaa cctcacaaca attagccgat atgatggttg gaagaacggt ttcattcaaa
    17581 acgatgaaaa aagaagcgaa gcctcaagaa gtcgttttgt ctattgaaaa tctagtggtg
    17641 aaagaaaatc gtggattaga agccgtgaaa aacttgaact tagaggttcg tgctggcgaa
    17701 gtacttggta tcgctggaat cgatggaaac gggcagtcgg agttgatcca agctttgact
    17761 ggtttgcgaa aggcagaaag cggacatatc aagctaaaag gggaagacat cactaataaa
    17821 aaaccccgaa aaatcactga acatggtgta ggacacgtgc cagaagaccg tcataaatac
    17881 gggttagtcc tagatatgac attatctgaa aatatcgcac tacaaaccta tcatcaaaaa
    17941 ccttacagta aaaacggcat gctgaattat tcagtaatga atgaacatgc cagagaattg
    18001 atcgaagaat atgatgttcg aacaacgaat gaacttgttc ccgcaaaagc tttatcaggc
    18061 ggaaatcagc aaaaagcaat tatcgctcgt gaagtcgacc gagatcctga tctgttgatt
    18121 gttgcaaatc caactcgtgg actggatgta ggtgcgatcg aatttattca taaacgtctg
    18181 atcgaacaaa gggacaaata caaagcagtg ttactgatca gtttcgaatt agaagaaatt
    18241 ttaaatgttt cggatcgtat tgctgttatc catgaaggag aaattgtcgg tatcgttgat
    18301 ccgaaagaaa catctgaaaa tgaattaggt ctattgatgg cgggctatac cttagaagaa
    18361 gcacgaaaag agttagaaaa gggggctggc gcacatgaat gatcgcagcg aaaaattccg
    18421 taatttatta gtgcctgtac tttcagttgt tttaggattg atcttaggcg cgatattgat
    18481 ggctgctttt ggttttcagc ccatccaagg ttattcttct atgctagatg cagcccttgg
    18541 ttcgcaaaga gggataggtg aaacgttaag gcaagcaacg ccgttgattt ttacagcatt
    18601 aggtttttct gtagctaact cagctgggtt tttcaatatt gggctttctg gacaagcact
    18661 ttgcgggtgg atcgtcagtg tctgggtggc acttgcgttt ccagatctgc caaaagttgt
    18721 tttgcttccg ttatgcgtga tcttaggtgc cttagctggt gcgatggcag cggctgttcc
    18781 aggtttactt cgagcatttt ttggaacaag tgaagtgatc gtaacaatca tgatgaacta
    18841 tatcttatta tacgtaagca catttgcttt acatgaagtg atgcctgaaa gctatcgctc
    18901 aagtttggac tcttccaata tgatcagtca aaatgcctca ctgcggttac catggttaac
    18961 acaagctttt ggcggctctc gcgtaaactc aggattattt ttagcaatca tcgcgcttat
    19021 tttcgtttgg ctgctgatga agaaaacgac tttaggattt gaaatccgtt ctgttggatt
    19081 gaatcctttt gcttctgagt atgcaggaat gagtagtaaa cgtacgatcg ttttgtcgat
    19141 ggtcatttct ggcgctttgg cagggcttgg cggtgtggtt gaaggattag gaacgtatca
    19201 aaacttcttt gttcaaacga cttcgctatc tattggattt gacggaatgg ctgtttcctt
    19261 gcttggttct ggatcagcaa tcggtattct tttatcagcg atcttgttca gtattttgaa
    19321 gatcggtgga cttggcatgc agacaggagc aggtgttccg tttgagatcg tcaatgtatc
    19381 gattgctttg attatcttct ttgtcgggat caacttcctg attcgtttcg tcatggctaa
    19441 agtcttccaa gggaaaaaac aagaagagat cgttgcgaca atagaatcga aaccaacgaa
    19501 tcaaaaccat gaagggggcg aactataatg tcgactatcg aattaattgc cttgatcctt
    19561 acttctacac tggtttattc aacaccgcta attctaacgt cactaggcgg aactttttct
    19621 gaacgaagcg ggatcgtaaa cgtagggcta gagggaatca tggtcatggg tgcttttagt
    19681 tccatcgttt tcaacttgac gatgagtcca tcacttggtt ctatgacacc atggatcgct
    19741 attttagtgg gtggcgtcgt aggtatccta ttttctctga ttcacgcagt agcaacagtc
    19801 agtttgcgtg ctgaccatat tatcagcggg acagtaatta atctgatggc acctgcttta
    19861 ggtgttttct tgatcaaagc atggtatggt aaaggtcaaa ctgataacat cacgcagaat
    19921 ctggggtatt tttctttccc aggattagca gatattccgg tcattggacc aattttcttt
    19981 aaaaatacat tcttacctgc ttattgtgct attttgattg ctgtcctagc ttgggtgatc
    20041 atcttcaaga cgaaattcgg cttgcgcctc cgttcagttg gtgaaaatcc tcaagctgcc
    20101 gacacattag gtatcaatgt atatgctatg cgttattcag gcgtactgat ttctggcttg
    20161 ttaggcggta tgggcggtgc tgtttttgct cagtcgattt ccggtaactt ttcagctggt
    20221 acgatcgttg gacaagggtt catctccatg gctgctatga tctttggtaa gtggaatcct
    20281 ttaggggcaa tgggtgcctc attgttcttt ggttttgctc aaagcttgag tatcattggc
    20341 gcacaattac cagttatttc ttcgattccg ccagtattgc tgcaaattgc tccatatttg
    20401 ctgacaatca ttgtgctggt tgttttctta gggaaagctt ctggtccaaa agcaaacggg
    20461 aagaactata tcaaatcaaa ataatctttt agcgaataaa aagggtgggt tacgggaagt
    20521 gtttttcgtc tcgccctttt tgttttaaag gcaataaaaa taaaaagaaa gaaggaataa
    20581 tcatgtttaa acgcgtacat ctgatcgtca tggattcagt aggaattgga gaagcaccag
    20641 atgccgataa gttcggtgat gttggttctg atacattagg acacattgcg aaagaagcag
    20701 gattgaacgt tccacattta gagcagcttg gtttaggaac gatccgtcct cttgaaggtg
    20761 tggaatcagt gaaagatcat caaggctatg cgacgaaatt agaagaagtt tctgtaggga
    20821 aagatacgat gacaggccac tgggaaatca tgggattgaa tatcaaaact ccatttcgtg
    20881 tgtttcctaa tggattccct gatgatctga tcaaacaaat cgaagaattt tctggccgta
    20941 aagtcgtatg taacaaacct tatagcggaa cagctgttat tgacgattac ggtgaacacc
    21001 aaatgaaaac aggcgattta attgtatata cttctgccga tcctgtcctt cagatcgcgg
    21061 cacatgaaga aatcattcct ttagaagaat tatatcggat ttgccaattc gttcgtgata
    21121 taacaaaaga tgatccgtat atgattggcc gaatcattgc acgtccgtac gtgggtgaac
    21181 caggagactt cacacgaaca agcaatcgcc atgattatgc gttgaatcca ttcggacaca
    21241 cagtccttga ttctttgaaa gaagcaggaa aggacgtgat tgctgttgga aagatcaacg
    21301 atattttcaa cggacaagga atcactgaat ctgtccgcac gaaaagcaat atggatggcg
    21361 ttgaccagct gctgaaagtt atgaaaaacg atttttcagg aatcagcttt accaatttag
    21421 tagattttga tgcattatac ggtcatcgtc gggatgtagt cggctatgcg catgcgattg
    21481 aagaatttga cttacgaatt ccagaattgc ttgaagcgat ggaagaagac gacttgctaa
    21541 tgattacagc cgatcacgga aacgatccga cgtttactgg taccgatcat acgcgagaat
    21601 atgtaccgtt attggtttac agtaaaaaaa tgaaagaaca aggggcattg cctcaaggat
    21661 attattcaga tatttcagca acgattgctg agaactttag tgtttcttcg actgaaaatg
    21721 gcgaaagctt cttgaaatta ttaaaataat ctttttaaat aggagaaagc aaatgaccaa
    21781 gttaagcgag atgttacaag aaacgaccca gtttatcctt gataaaggag taaaagaaat
    21841 tgattttggt ttgattctag gttcaggatt aggtgaatta gcagatgaaa tcgaagatgc
    21901 tgtaatgatt tcttatgatg agatcccgtt ctttcctgtt tcgacagtag ttgggcatgc
    21961 aggaaagcta gtttatgggt ctctggcagg caagaaagtg ttagccatgc aagggagatt
    22021 ccactactat gaaggtcatt ccatgcaaac agtgacctat ccagtacgtg tgatggccgg
    22081 actaggggcc cattcagtca ttgtgactaa tgcatgtggt ggtgtcaacg aatcatttgt
    22141 accaggagat ttgatgctga ttaccgatca tatcaatttt actggtgaaa atcctttgat
    22201 cggtccgaat gaagatgcaa tgggccctag atttccagat atgagtcaag cttatacgcc
    22261 tgactatcaa gcaacagcaa aagcagcagc agaaaaacta ggtttggatc ttaaagaagg
    22321 cgtatatatg ggctattctg gaccaactta tgaaacgcct gcggagatcc gaatgtctcg
    22381 gacaatagga gccgatgcag tagggatgtc gactgttcca gaagtcatcg tagcagctca
    22441 cagcggatta aaagtgttag gaatctcttg tattaccaac ttagcagcag gtatgcaagc
    22501 gaatctgagc catgaagaag ttgtagaaac aactcagaga gtcaaacaat cttttaaagc
    22561 attggttaaa gaaacattga cattattgta ataggaggaa caataaaatg agtgtgcata
    22621 ttgaagcgaa agaaggcgag atcgccgata agattttact tccgggagat cctttgcgag
    22681 ctaaatatat tgcggagact tttttggaag atccagtttg ttacaatcag gtacgcggta
    22741 tgttaggctt taccggcaaa tataaaggag aacgtatttc tgttcaagga acaggaatgg
    22801 gaatgccatc agccaccatc tatgcccatg aattgatcca gtcgtatggt gtaaagaaat
    22861 tgattcgagt aggtacatgc ggtgcattgt caaaagacgt ccatgttcgt gatttagtac
    22921 tagcacaagg tgcagcgacc agttcttcga tgatcgaaaa aaatttccaa gcctttcatt
    22981 ttcctccaat cagtgatttc aatctattac tgaaagcata tgagatagct aaagaaaagg
    23041 gctatacggt tcatgtagga aatgttcttt cggaagattc tttctacaaa gatgatttga
    23101 cagagacgtt ccaattagct gaacttggcg ttttaggagt ggaaatggaa gcagcggctc
    23161 tttattactt aggcgcgaaa taccatgtgc agacattaag tttgatgacc gttagcgacc
    23221 atttgatcac cggtgaagaa acaacagctg cagaacgtca atctacgttc aatgaaatga
    23281 tcgaagtagg attggaaaca gcgatagcag aataagaagg aaatgaaaaa gctgccctgc
    23341 attaagtaat aagaacatcc aagcaaaaat agctcctcat gtttttgact tggctggact
    23401 tattattgca aatgtaagct tttgaacacc gtttaccaag aggttgtgaa tctgccgttt
    23461 aactctgagt cacaaggaac aatttcaaaa aacagctttt catgtttgat gaatattgtg
    23521 acttgtgacc gagaagttgg caggagaaaa ccgtttatac gaaaaaaggg actgtgacaa
    23581 atcgtgtcac agtccctttt ttatagtgtt ttttataggt agtatttttt agcaactgtt
    23641 aagtcatcat ttaattcata aacaagtggt tgacctgttg gaatttcaag atccatgatg
    23701 tcttcgtcag agataccttc gatatgttta gctagggcgc gtaatgagtt accatgtgca
    23761 gctactaaaa cagttttgtt gtctagtaat gctggagcaa tttcatcttg ccagaatggc
    23821 aaagcgcgtt ctaatgtcac tttcaagttt tctccaccag gaatatcgcg tttgtctaac
    23881 attgcgtaac gacggtcatt tgctgcagaa ccttcgtcag tttcttccat taatggagga
    23941 agagtatcgt aagaacgacg ccagatgtgc acttgttcgt cgccgtattt ttcagctgtt
    24001 tcttttttgt tcaaaccttg taatttacca tagtgacgtt cgtttaagcg ccatgatttg
    24061 atttgtggta cccaaagttg atctgaatat tctaagatca agttacatgt tttgattgca
    24121 cgagttaaaa cagaagtgta agcaacatca aattcgattc cagcttcttt gattttgcgt
    24181 ccgccttctt ttgcttcttc gattccttct ggtgctagat ttacatcagc ccaaccagta
    24241 aattggttca atgcattcca ttcactaaga ccgtgacgag aaaaaactaa ttttggcatg
    24301 tttagctctc cttttaagat aggtttatat ttctgaaatt ttcagttctg ttttattgta
    24361 caattttttg gaagagattt ccatcgaaaa attagataag attctatgag aaaacaagta
    24421 gagaatataa aaaaacgaac agtgcccacg caactgttcg tttttaggta ttagatgcat
    24481 aattgctcga tttctttttc aggtaaattg atatatttat aacatgttcc aactgaaaca
    24541 ccgcattttg aagaaataaa ttggatcgtt tctttttttt cataatagag acgtcggatt
    24601 tttttgatcg tttttgcatc gatttttggt cttccgccga tttttccttt tttacgagct
    24661 tcatctaatc caactaatgt acgttctttg atcaatgcgc actccatgtt tgctaggttt
    24721 tccattaatt ggaaatagat ttttcccatt tcgcgcgtat cgattccttc atcaagacta
    24781 atcaagtgca gcccgcgatc tttgaataat tgcgtgagtt ctgttaattg ccgcgtagat
    24841 ttgcctaatc gatgaagttg gcaaatgact agtgcatcgc cttgttgcat gtcagcgatc
    24901 actgactcca aatgaacagc agtagaatca ttttgttcca cttcatatgt ctcatggaaa
    24961 atttcttgac aaccaaagtc agataattga tcaacctgag ttgttaaatc aacgtcattt
    25021 atggttgtgc gtgcataacc aataattttc atggtgattc ctttctagca gtgattttct
    25081 aactggatat aacagtaaaa atgtagcata aagtacgtca aaaagatagt tttttcgcaa
    25141 attttccgct gtcttttttt attggatgat caagcagttt ttctttattt acgacggatt
    25201 gcgtcaagaa tctcaacgcc tttttctgag ccgacaacta ctttagaaac catgtttagg
    25261 aaaagcccat gttctactac cccaacaagt tcatctaaat aggtagctaa gctttctggc
    25321 tgttcgatga cttctagatg cagatcaatg atgtaatgac caccatctgt ggttaagact
    25381 tctccgtttt cgtctgtacg caagacgggt tggaatcttt tttcttcaaa aatatgaagt
    25441 agctgttggg agccataagg gatcacttca actgggagtg ggaacttccc aagtttatcg
    25501 actaatttag aagaatcaac gatccaaatc gtttcttttg agtacgtagc gactattttc
    25561 tcgaaaagca aagcagcgcc gccgcctttg atcccttgaa aatcagcact gatttcatca
    25621 gcaccgtcta ttgtcaaatc gactacgggg acttcatcaa tactctttaa cggtattcct
    25681 aatttttccg cttgttcttt tgtcgcattt gaagtagtaa ctcctgtgat acgtaaacct
    25741 tcttcacgca tacggcgacc aatctcttct accatataat aggcggttga accggtcccg
    25801 agacctacga tcatcccgtc ctttacgaat ttcgcggctt caatgccagc taattgtttt
    25861 aaattcatct ttgcgtccac ctttttttag tttgagcatc gtgctttcct cactatttta
    25921 gcgtgattta cggtaaaaag ataccattct tttttattcc aataaagctt tttcaaaaaa
    25981 aattgcatct cttgttgaca tgttttttca ttcgtgatat tctaacaaag gtgctttatc
    26041 tacaggtttc tgtgaagaaa cgtgctgact gtttatcaaa gcatatttga taaggatgca
    26101 gacattgcat ttatttttta tcacaaaaaa agaaccacct ggatgtgtgg aactagacgc
    26161 aaatcgtggg aaggaggaaa caaggaatgc ctacaattaa ccaattagta cgtaaacctc
    26221 gtaaatcaaa ggtggaaaaa tctaattcac ctgctttgaa caaaggatat aacagcttta
    26281 agaaaactca aactaacgta aactcacctc aaaaacgtgg ggtagcaact cgtgtgggta
    26341 caatgacacc taaaaaaccg aactcagctt tacgtaaata tgcacgtgtt cgtttgtcaa
    26401 acttaattga agttactgct tatatcccag ggattggtca taacttacaa gaacacagtg
    26461 ttgtattatt acgcggtggt cgtgtaaaag acttaccagg ggtacgttac catatcgttc
    26521 gcggtgcttt agatactgct ggtgttaacg accgtaaaca aagccgttct aaatacggaa
    26581 ctaaaaaacc taaagcttaa ttttaattat taaacaaatg aaacttgctt ctactatata
    26641 gaagtaatta ctatgaacaa tatttcggaa ggaggagtta cggatgccac gtaaaggtcc
    26701 tgttgcaaaa cgtgatgttt taccagatcc tatttataac tcaaaattag taactcgctt
    26761 gatcaaccgt gtaatggttg acggaaaacg cgggattgca gctaacatta tctataatgc
    26821 ctttgacttg atcaaagaat ctacaggtaa cgatccatta gaagtgtttg aacaagcaat
    26881 gaaaaacgtt caacctgttc ttgaagttaa agcacgtcgt gttgggggtt caaactacca
    26941 agtaccagtt gaagttcgcc ctgaacgccg cgttactcta ggtcttcgtt gggtagtaaa
    27001 ctacgctcgc ttgcgcggtg aacacacaat ggaagaacgc ttagcaaaag aaatcatgga
    27061 tgctgcaaac aacacaggtg cttctgttaa aaaacgtgaa gacactcata aaatggctga
    27121 tgccaaccgt gcgtttgctc actatcgctg gtaagattct ctctgtttgg tcggctttta
    27181 taagtcgacc tcagatagtg tccttatttt tagcaactag atagtaaaga gaggagaaac
    27241 aaggagaatg accagagaat tttctttaca aaacactcgt aatatcggta tcatggccca
    27301 catcgatgct ggtaaaacga ctgctactga acgtatcttg tactatactg gtaaaatcca
    27361 taaaattggt gaaactcatg aaggagcttc acaaatggac tggatggaac aagaacaaga
    27421 acgtggtatt acgatcactt ctgctgctac tacagcacaa tggaagggtc accgaatcaa
    27481 catcatcgac acaccaggac acgtagactt cacagttgaa gttgaacgtt cattgcgtgt
    27541 acttgatggt gctgtaactg ttcttgatgc acaatcaggt gttgaacctc aaactgaaac
    27601 agtttggcgt caagcaacaa cttatggtgt acctcgtatc gtatttgcaa acaaaatgga
    27661 caagatcggt gctgacttct tatattcagt atcaacttta catgaccgtt tgcaagcaaa
    27721 cgctcaccca atccaattac caattggtgc ggaagacgac ttcacaggaa ttatcgacct
    27781 tgtaacaatg aaggctgaaa tgtatacaaa cgatcttgga acagagatcg aagaaacaga
    27841 aattcctgaa gaataccgcg aattagctga agaatggcgc gaaaaattgg ttgaagctgt
    27901 agctgaaact gatgaagaac ttactttgaa atacttagaa ggtgaagaaa tcactgaagc
    27961 tgagttaaaa gaaggtatcc gccgcgcaac agttaacgta gaattctacc cagtactatg
    28021 tggttcagca tttaagaaca aaggggttca attactattg gacgctgttc ttgattactt
    28081 gccatcaccg ttagatatcc cagctatcaa agggattgac cctaaaactg atgaagaagt
    28141 agaacgtcct gcagacgaca gcgctccttt ctcagcttta gcatttaaag ttatgactga
    28201 cccattcgta ggtcgtttaa ctttcttccg tgtgtactct ggtgttttac aatcaggttc
    28261 atacgtacaa aacgcaacaa aaggcaaacg tgaacgtgtt ggtcgtatcc tacagatgca
    28321 tgccaactct cgttcagaaa tctctgaagt ttacgctgga gatatcgctg ctgctgttgg
    28381 tttgaaagac acaactactg gggacacact atgtgatgaa aagagtctag ttattcttga
    28441 atccatggaa ttcccagaac cagttatcca agtcgctatt gaacctaaat caaaagctga
    28501 ccaagataaa atgggtgtgg ctttacaaaa actatctgaa gaagatccta ctttccgtgc
    28561 tgaaacaaac gtggaaacag gcgaaacaat catcgctggt atgggtgaac ttcacttaga
    28621 tatcatcgtt gaccgtatgc gtcgtgaatt caaagttgaa gctaacgtag gtgcgcctca
    28681 agtatcttac cgtgaaactt tccgtgctgg cactcaagcc gaaggtaagt ttgtacgtca
    28741 gtctggtggt aaaggtcaat acggtcacgt atggattgaa tttacaccaa atgaagaagg
    28801 tgctggtttc gaatttgaaa atgcgatcgt cggtggggtt gttcctcgtg aatacattcc
    28861 agctgttgaa actggtttga aagatgctat ggaaaatggt gtcttagctg gctatccatt
    28921 agtagatatc aaagctaaac tttacgatgg ttcataccat gatgtcgatt caaatgaaac
    28981 tgccttccgt gttgctgctt ctatggcatt acgtgcagca gctaagaaag ctaatccagt
    29041 aatccttgaa ccaatcatgg ctgtagaagt tgttatccct gaagattatt taggtgatgt
    29101 tatgggtcac gtaactgctc gtcgtggacg tgttgaaggt atggaagctc gcgctggcgg
    29161 ccaacaagtt gttcgtgcga tggttccact tgctgaaatg tttggttatg ctacaactct
    29221 tcgttctgct actcaaggtc gtggtacatt tacaatgaca tttgaccact acgaagatgt
    29281 accaaaatca gtacaagaag aaatcattaa gaaaaacggc ggaaaagctg aataatttct
    29341 taaaaccgga tagtcctgca aagagattat ccaaagagac tatattttta atatagtttc
    29401 gtgtaaaata attatcgatg atatgggcat gtggtgtacc ttgtgtacat catataccta
    29461 tcagacaaat aaaaaatata ttgtattttt aggaggacat tttaaaatgg caaaagaaaa
    29521 atttgaccgt tctaaaccac acgttaacat tggtactatc ggacacgttg accatggtaa
    29581 aactacatta acagctgcaa tcacaactgt actatctaag aaaaacggcg gccaagctat
    29641 ggcttacgat caaatcgatg gtgctccaga agaacgcgaa cgcggaatca caatctcaac
    29701 agctcacgtt gagtatgaaa cagatacacg ccactacgct cacgttgact gcccaggaca
    29761 cgcggattac gttaaaaaca tgatcactgg tgctgctcaa atggacggag ctatcttggt
    29821 agtttctgct gctgacggcc caatgcctca aactcgtgaa cacatcctat tgtctcgtca
    29881 agttggtgtt ccttacatcg ttgtattctt gaacaaagta gacatggttg atgacgaaga
    29941 attactagaa ttagttgaaa tggaagttcg tgacctatta acagaatacg aattccctgg
    30001 tgacgatgtt cctgtagttg ctggatcagc tttgaaagct ctagaaggcg acgcttcata
    30061 cgaagaaaaa attcttgaat taatggctgc agttgacgaa tacatcccaa ctccagaacg
    30121 tgacaacgac aaaccattca tgatgccagt tgaagacgtg ttctcaatta ctggacgtgg
    30181 tactgttgct acaggtcgtg ttgaacgtgg acaagttcgc gttggtgacg aagttgaagt
    30241 tgttggtatt gctgaagaaa cttcaaaaac aacagttact ggtgttgaaa tgttccgtaa
    30301 attgttagac tacgctgaag ctggagacaa cattggtgct ttactacgtg gtgttgcacg
    30361 tgaagacatc caacgtggac aagttttagc taaaccaggt acaatcacac ctcatacaaa
    30421 attctctgca gaagtatacg tgttgacaaa agaagaaggt ggacgtcata ctccattctt
    30481 cactaactac cgtccacaat tctacttccg tacaactgac gtaacaggtg ttgttgaatt
    30541 accagaagga actgaaatgg ttatgcctgg cgacaacgta acaatggaag ttgaattaat
    30601 ccacccaatc gctatcgaaa acggtactaa attctcaatc cgtgaaggcg gacgtacagt
    30661 tggtgccggt gtcgttacag aaatcaaagc ttaattcact taagttttaa agtaaagcaa
    30721 catttattcg gacgtaatcg ctcggaacga aggtcttagg atctttgttc cgagcttttt
    30781 tatttattgc aggatcagga aaaaagacag gagtattata aatagaagaa acacgaaata
    30841 aaagagtcag tattttctaa atgaaacttt atgaaaacaa aatgtttttt acaagaaaaa
    30901 gccttgcttt gtgagtttat atatattata atgacaaagg tgcgtttact ttagtgaatt
    30961 gcacagacgt aatcagaatg atttcgtcgg ctaagaaacg agaggttgcg acacgcccgg
    31021 acgctttgcc acgaacgagc gtgacggaaa ttttcgtgga gctatgtcta cttttcaaaa
    31081 taggcgaagg agggaacaag atggcaaaac aaaaaattcg tatccgttta aaagcgtatg
    31141 aacaccgtat tttagatcaa tcagcggata aaatcgtgga aactgcaaaa agaactggag
    31201 ctagcgtgtc tggtccaatt ccattaccaa ctgaacgcag tctttacaca atcatccgtg
    31261 cgactcataa atacaaagat tcacgcgaac aattcgaaat gcgtacacac aaacgtctta
    31321 tcgacattgt gaacccaaca ccaaaaactg ttgatgcttt gatgaagcta gacttaccat
    31381 ctggtgtaaa catcgaaatc aaattataaa actaaaacaa aaataatgga ggtgtactca
    31441 tgaccaaagg aatcttaggg aaaaaagtgg gaatgacaca aatcttcact gaatctggtg
    31501 aattaattcc agtaactgtt gtagaagcta ctccaaacgt agtactacaa gtgaaaacaa
    31561 tggaaacgga tggctacgaa gctattcaag ttggttacca agatatgcgt gaagttttat
    31621 caaacaaacc tgcgaaaggt catgttgcaa aagcaaacac ggctcctaag cgcttcattc
    31681 gtgaattcaa aaatgttgag ctaggagaat atgaagtagg aaaagaaatt acagtagatg
    31741 ttttccaagc aggagacatt attgatgtaa caggtactac gaaaggtaaa ggattccaag
    31801 gggttatcaa acgccacgga caaagccgcg gaccaatggc tcacggttct cgttaccatc
    31861 gtcgtcctgg gtcaatgggt ccagttgcac ctaaccgtgt atttaaaaac aaacgtcttg
    31921 ctggccgtat gggtggcaac cgcgtaacta tccaaaactt ggaagttgta cgtgtcgatg
    31981 cagaaagaaa tgttatcttg atcaaaggta atgttcctgg agctaaaaaa tctttaatta
    32041 ctatcaaatc agctgtgaaa gctaaataat tgtaggaaga aaggaggaac taaggaatgc
    32101 cgaatgtagc attattcaaa caagatggaa gccaaaacgg tgaaatcaca cttaacgaag
    32161 aaatcttcgg aattgaacct aatgaaagtg ttgtttacga tgcaatcgta atgcaacgtg
    32221 cgtcattaag acaaggaaca cacgcggtta aaaaccgtag cgctgttcgc ggcggcggac
    32281 gtaaaccatg gcgtcaaaaa ggaacaggtc gtgcacgtca aggatctatc cgctcaccac
    32341 aatggcgtgg aggtggcgta gtctttggac caacaccacg ttcttacagc tacaaacttc
    32401 ctaaaaaagt tcgtcgttta gcaatgaaat ctgtattgtc agaaaaagtt gctgaaaaca
    32461 acttggtagc aatcgaaggc ttgaacttcg acgcaccaaa aacaaaagaa ttcaaacaag
    32521 ttcttgctaa cttatctatc gactctaaag tattggttgt tctagaaaaa ggtaacgact
    32581 ttgctgcttt atcagcacgt aacttaccaa acgtttctgt agtaacttct gataatgtga
    32641 gtgtgctaga cgttgtatca aatacaaaag tgttagcaac acaaactgct cttactcaaa
    32701 ttgaggaggt gcttgcataa tgaacttact agacgtaatc aaacgcccag tgatcactga
    32761 aaaatcaatg cttgccatgg atgacaagaa atacactttt gaagtggaca ctcgcgcaaa
    32821 caaaacttta gtaaaacaag cggtagaagc tgcttttgac gttaaagtca aaaacgtgaa
    32881 catcgtgaac gtacgtgcga aattcaaacg tatgggcaaa tatgcaggat atacaaaaaa
    32941 acgtcgcaaa gcgatcgtta cattgactga agattcaaaa gaaatccaat tattcgaagc
    33001 tgctgaataa gcactaatag ataactcatt aaattaggag ggaaaaacgt ggcgattaaa
    33061 aagtacaaac ctacctcaaa tggtcgtcgt aacatgacag gttctgattt tgctgaaatc
    33121 acaacatcaa cacctgaaaa atcattgtta caaccattga aaaaccatgc tggacgtaac
    33181 aacaacggcc gcatcactgt acgtcatcaa ggtggcggac acaaacgcca atatcgcgtg
    33241 atcgacttca aacgtaacaa agataacgtt gttgcaactg ttcaaacgat cgaatatgat
    33301 ccaaaccgtt cagctaacat cgcgttagta cactatgaag atggagtgaa agcttacatc
    33361 ttagcaccta aaggactaga agtgggtatg aaacttgttt caggtccaga agcagatatc
    33421 aaagtcggaa atgctcttcc attagaaaac attccagttg gtactgttat ccacaacatt
    33481 gaaatgaaac ctggtaaagg tggacaattg atccgttctg ctggtacaag tgctcaagta
    33541 cttggtaaag aaggcaaata cgtattgatc cgcttgaact ctggtgaagt tcgtatgatc
    33601 ttagctgcat gccgtgctac aatcggttct gtaggtaacg aacaacacga attaatcaac
    33661 atcggtaaag ctggacgctc tcgttggatg cgtaaacgcc caactgtacg tggtagcgta
    33721 atgaacccta atgatcaccc acacggtggt ggtgaaggta aagctcctat cggacgtaaa
    33781 gcaccagttt ctccttgggg tcaaccagct cttggttaca aaactcgtaa caaaaaagct
    33841 aaatcagaca aacttattgt tcgtcgtcgc aaaaataaat aattactttg accatgtgtc
    33901 gcacattttg agaggaggtt caccatgggt cgtagtttaa agaaaggacc ttttgtcgat
    33961 gagcatttaa tgaaaaaagt tgaagctcaa gcaggggttg aaaagaaaaa agttatcaaa
    34021 acttggtcac gccgttcaac agttttccca agttttgttg gatataccat cgcagtttat
    34081 gatggacgta aacatgtacc agtttacatc caagaagaca tggtaggaca caaattaggt
    34141 gaatttgcac ctacaagaac ttatcgtgga catgctgctg acgataagaa aacgaaacgc
    34201 taatttgagg ggaggataaa tccaaatggc agaacaaatc acatcagcta aagcaactgc
    34261 aaaaacagtt cgcacttcac ctcgaaaagc ccgtttagta attgacctta tcagaggtaa
    34321 aagtgtcgca gatgcaattt caatcttgaa attcacacca aacaaatctg ctggaatcat
    34381 tgaaaaagta ttgatgtcag cagttgcgaa tgcagaaaat aactttgact tagatgttga
    34441 aaacttggta gtaagcgaag cttttgttaa cgaaggacct acaatgaaac gtttccgtcc
    34501 tcgtgcaaaa ggatcagctt ctccaatcaa caaacgtaca agtcatatca cggtagtcgt
    34561 atcagaaaaa taaggaggga taatcagtgg gtcaaaaagt acatccaatt ggaatgcgtg
    34621 taggcatcat ccgcgactgg gatgctaaat ggtatgctga aaaagagtat gctgagttct
    34681 tacacgaaga tttaagaatc cgtaaattta tttcaactaa acttgctgat gctgctgtat
    34741 caacagttga aatcgaacgc gcaacaggtc gcgtaaacat ttcaattcac acagctaaac
    34801 caggtatggt tattggtaaa ggcggttctg aagtcgaaag cctaagaaaa gaattaaaca
    34861 aattaactgg taaaagaatc catatcaata tcgtggaaat caaaaaacca gatctagatg
    34921 caaaattagt aggtgaagga atcgcacgtc aattagaaaa ccgtgttgct ttccgtcgcg
    34981 ctcaaaaaca agccatccaa cgctcaatgc gtgctggcgc tcaagggatc aaaactcaag
    35041 tatctggtcg tctaaacgga gcagatatcg ctcgttcaga aggatactca gaaggaactg
    35101 ttcctcttca tactttacgt gcggacattg attacgcatg ggaagaagca gatacaacat
    35161 acggaaaact aggagttaaa gtgtggatct atcgtggaga aattcttcca actaaaaaaa
    35221 acactgagaa aggagggaaa taatcatgtt agtacctaaa cgtgtaaaac accgtcgtga
    35281 attccgcgga aaaatgcgcg gggaagctaa aggcggaaaa gaagtagcat tcggtgaata
    35341 cggtttgcaa gctgttgatt cacattggat cacaaaccgc caaatcgaag ctgctcgtat
    35401 cgcaatgact cgttacatga aacgtggtgg gaaagtatgg attaaaattt tccctcacaa
    35461 atcttatact gccaaagcaa ttggggtacg tatgggttct ggtaaagggg cacctgaagg
    35521 atgggttgca ccagtaaaac gtggtaaaat catgtttgaa atcgcaggcg ttcctgaaga
    35581 agtagctcgt gaagcgttac gtctagcttc tcacaaatta ccaatgaaaa ctaagatcgt
    35641 aaaacgtgag gaaatgggtg gtgaatcgaa tgaaggttaa agaaatcaga gaattaacca
    35701 ctgccgaaat gcttgatcaa gaaaaacaat taaaagaaga attgtttaat cttagattcc
    35761 aattagcaac aggtcaatta gaaaacactg cacgtattaa agaagtacgt aaatcgattg
    35821 cacgcatcaa aactgtgttg cgtgaacaag ctaagtaatt atggaaggag gccattaagc
    35881 gtatgactga aggaagaaat caacgcaaag tttatcaagg tcgcgtggtt tcagacaaaa
    35941 tggataaaac aattaccgtt gctgtcgaaa caaagaaaaa ccaccctatc tatggcaaac
    36001 gcatgaacta ttctaagaaa tacaaagtgc atgatgaaaa caacacagca aaagttggcg
    36061 acatcgtgag aattatggaa actcgtccat tatcagctac aaaacgtttc cgtttgttgg
    36121 aagtagtcga agaagcagtt attatctaat aacacgagat tttcctatat agattgaatg
    36181 caaaatctga aaggaggata cacaacgtga tccaagcaga aagtcgttta aaagtcgctg
    36241 ataactcagg cgcacgtgaa attttgacga tcaaagtcct tggtggatct ggtcgtaaaa
    36301 ctgctaacat cggtgatgtg atcgttgcta cggttaaaca agcaacgcca ggtggggttg
    36361 tcaaaaaagg tgacgtcgtt aaagccgtta tcgttcgaac aaaatcagga gctcgtcgta
    36421 cagacggttc atatattaaa tttgatgaaa atgctgcagt gattattcgt gatgataaaa
    36481 gccctcgtgg aacacgtatc tttgggccag ttgcacgtga actacgtgaa aacaacttca
    36541 tgaagatcgt ttcactagca ccagaagttt tataatcttg agacacttat caaaggaggt
    36601 gcgaaacagt tatgtttgtt aaaaaaggcg ataaagttaa agttatcact ggaaaagaca
    36661 aaaacaaaga aggcgttgta ctagcagcgt tcccgaaaaa agataaagtt attgtcgaag
    36721 gtgtaaatgt cgttaaaaaa caccaaaaac cttctcaagc tgctcctcaa ggtggaattg
    36781 ttgagatgga agcgccaatt catgtttcta acgtgatggt ggttgactct actggtgtag
    36841 ctggccgagt tggctacaaa gaagtagacg gcaaaaaagt ccgtgtttct aaaaaaaccg
    36901 gtgaagtttt agataaataa aagtttaagg aaggagggtc ttactgaatg aaccgcctaa
    36961 aagaaaaata tcttaaagaa gtaactccat cattgatgga aaaatttaac tatagctctg
    37021 ttatgcaaac acctaaagtt gaaaaaatcg tcatcaacat gggtgttggt gatgcggtat
    37081 caaacgctaa aaacttagat aaagcagttg aagaattaac tttgatcact ggtcaaaaac
    37141 caatgattac aaaagctaaa aaatcaatcg ctggattccg tttacgtgaa ggaatgccaa
    37201 ttggtgcaaa agttacattg cgcggagaaa gaatgtacga attcttagac aaattggttt
    37261 ctgtttcact accacgtgta cgtgacttcc atggtgtaag taaaaaagcc tttgacggtc
    37321 gtggaaacta tactttaggt attaaagaac aattgatctt cccagaagta gattatgatt
    37381 tagtagataa agtacgtggt atggacatcg ttattgtaac aacagcaaac tctgatgaag
    37441 aatctcgtga gttgttgaca caattaggca tgccattcca aaaataatta aaggaggcga
    37501 actacgtggc taaaaaatca atgattgcta aaaacaaacg tcctgcaaaa ttttcaacac
    37561 aagcttatac tcgttgcgaa cgttgcggac gtccacattc agtttatcgt aagttccatc
    37621 tttgccgtat ttgcttccgc gaacttgcct ataaaggtca aattcccggc gtgaagaaag
    37681 ctagctggta aaaagtaaat tcgcataaga aggaggtaaa agatcaatgg tcatgacaga
    37741 tccaattgca gattttctaa ctcgtatccg taacgcaaac atggttaaac atgagtcttt
    37801 agaagtacct gcatcaaaaa ttaaacgtga catcgctgaa atcttgaaac gtgaaggttt
    37861 cgttcgtgat gttgaataca tcgaagatga caaacaaggc gtgatccgtg ttttcctaaa
    37921 atttggtaaa aacggcgaac gtgttatcac aaacttaaaa cgtatctcta aaccaggttt
    37981 gcgtgcttat gtcaaagctg acgaagtacc aaaagtattg aacggtttag gtatcgcaat
    38041 catttcgact tctgaaggtg ttgtcactga taaagaagct cgtgaaaaaa atatcggcgg
    38101 cgaagttatc gcttacgtat ggtaatcaag tagaatctac aaggaggtgt ctttaagtga
    38161 gccgtatcgg aaataaagtc gttgttatcc ctgaaggagt aacagttact caagacggaa
    38221 acaacgttac agttaaagga ccaaaaggtg aattgactcg tactttttca gcagatatca
    38281 aaatgaatat cgaaggaaac gaagtaactt tcactcgtcc aaacgacagt aaagaaatga
    38341 aaacaattca tggaacaact cgtgcgaact tcaacaacat ggttgtaggt gtcagcgaag
    38401 gtttccaaaa agcgttagaa ctaatcgggg ttgggtaccg tgcacaatta caaggatcaa
    38461 aacttgtatt gaacgttggt tactcacatc cagtagaaat cacaccacca gctggagtaa
    38521 ctgttgaagt accagctaac acacaagtaa ttgttaaagg tgcgaacaaa gaagaagttg
    38581 gcgaattagc tgcaaacatt cgtggaactc gtcctccaga accttataaa ggtaaaggta
    38641 ttcgttatgt tggcgaatat gtacgccgta aagaaggtaa aactggtaaa taatcgttta
    38701 gaaaaattgc atagaagcca gcagcaggaa aaaggcattt ggctgaagtt taccttcaaa
    38761 aaaatacatt tttacttgtg ccgcagcttc tatttttcga aacgtattta ctgcttgaaa
    38821 tagtagtaca ataaaaataa agaggtgaca attgtgatta caaaaccaga taagaacaaa
    38881 acacgtcaaa agagacatcg tcgtgtacgt aacaatatct ctggtactgc tgagcgccca
    38941 cgcttgaacg tttttcgttc taacaaaaac atctacgctc aaattattga tgacgtagcg
    39001 ggtgtaacgc tagcaagtgc ctctaccttg gataaagaaa tttcaggtgg aacaaaaaca
    39061 gaagcagcac aagctgtcgg taaactagtt gctgaacgtg cagctgaaaa aggcattaaa
    39121 gtagtagtct ttgaccgtgg tggatacctt taccatggcc gtgtgcaagc tttagctgaa
    39181 gctgctcgcg aaaatggact agaattttag aagaaggagg aataccattc atggtttata
    39241 tcgatccaaa acatttggaa ttagaagacc gcgttgttgc aattaaccgt gtaacaaaag
    39301 ttgttaaagg tggacgtcgt ctacgttttg ctgctttagt tgttgtcggt gacaaaaacg
    39361 gacacgtagg gtttggtaca ggtaaagctc aagaagttcc tgaagcaatc cgtaaagcaa
    39421 ttgaagatgc gaagaaaaac ttagttgaag tacctatggt tggttcaaca atcccacacg
    39481 aagtaatcgg tgcttttagt ggtggtagaa tcctaatgaa acctgctgta gaaggttctg
    39541 gggttgctgc tggtggacca gttcgtgccg tattagaatt agctggggta gcagatatca
    39601 cttctaaatc tttaggctca aatacaccaa tcaacgttgt tcgcgcaaca gttgaaggtt
    39661 tgaaacaatt gaaacgtgca gaagaagttg cagaacttcg cggcaaatca gttgaagaat
    39721 taatcggata aggaggacaa caataatggc tgaattaaaa gttactttaa aacgcagtat
    39781 tatcggacgt cctcaaaacc aacgcgatac agttaaagcg ttaggtctta caaagattaa
    39841 cagttcagtg gttaagcctt ctaatgaagc aattaaaggc atgatcaata ctgtttctca
    39901 cctagtggac gttgaagaaa tttaatttag aaaaatcata actagaacat taaggaggtg
    39961 ccaaacctat gaaacttcat gaattaaaac ctgctgaagg ttcacgccaa gtacgtaacc
    40021 gtgttggtcg tggtacttca tctggtaacg gaaaaactgc cggacgcgga caaaaaggac
    40081 aaaaagctcg ttcaggcggc ggtgtgcgtt taggatttga agggggacaa acaccattgt
    40141 tccgtcgttt accaaaacga ggattcacaa acgtgaaccg taaagactat gcagtcatta
    40201 atcttgatgt attgaaccgc tttgaagacg gagctgaagt aactcctgtt gctttagttg
    40261 aagctggaat cgtgaaaaac gaaaaagctg gaatcaaagt attagctaat ggggaactaa
    40321 acaagaaatt aactgtgaaa gcagcaaaat tctctaaagc agctcaagaa gcaattgaag
    40381 cggctggtgg atcaatcgag gtgatctaat gtttagacta ttaaaagatg cttttaaagt
    40441 aaaagacatt agatcgaaaa tcctatttac tgtatttgtg ttgtttgtat ttcgcctagg
    40501 tgcacatatt actgtaccag gcgtaaatgc tgcttcattg caaaaccttt cttctttgcc
    40561 atttttcaac atgttgaact tggtaagtgg tagtgcgatg caaaactttt ccattttctc
    40621 aatgggggtt tcaccataca ttactgcttc tatcgtcatt cagcttcttc aaatggacat
    40681 cgtgcctcga tttgttgaat ggtcgaaaca aggggaagtt ggtcgtaaaa aactgaatca
    40741 agcgactcga tatctgacat tagtattggc atttatccaa tctgtcggta tcactgctgg
    40801 attcaatcaa tacgctcaat taggtttcgt gaataatcct aacgtagcaa cttacgtaac
    40861 gatcggtttg attctaacag ccggtacgat gtttgttact tggctaggag aacagatcac
    40921 agaaaaaggt atcggaaatg gcgtatcaat gatcattttt gcaggtatca tttctagatt
    40981 gcctgaaagt atcagagaaa tttatgaaga ttactttata aatattgatc cttcagacat
    41041 atggaaatct gctatttttg tggccatttt actagtagcg gtcttgttga tcgtgacatt
    41101 cgtaacattt ttccaacaag ctgaacgcaa gatcccgatc caatatacga aacgcgtagc
    41161 tggcgcgcct acaagcagct atctgccgtt gaaagtaaat gcagctggag ttattccagt
    41221 tatctttgct agttcgttta ttgctacgcc aaatgctgtt ttacaagcat tgagcggtag
    41281 attcggttct gaaaactggt acaaagtgat gatggagatc tttaactata atacagcacc
    41341 tggtgctacg atttatacga ttctgatcgt tgccttcact ttcttctacg cctttgttca
    41401 agtaaaccct gagaaattag cggaaaactt gcaaaagcaa ggaagttata taccaagcgt
    41461 acgccctggt aaggggactg aagagtatgt ctcaagatta ctgatgcgtt taagtacagt
    41521 tggtgcagtc ttccttggtt tagtggcatt gcttccaatc attgctcaaa tggtttggga
    41581 tcttccacaa tcaatcggat taggcggtac aagcttactg atcgttatcg gtgtagcttt
    41641 agaaactgcg aaacagttag aaggcttaat gctgaaacgt aaatatgttg gattcattga
    41701 gtaagaaagc gtgttgaggt ttcccctcaa cacacgttct cacacattta ttaggaggga
    41761 aaacaatgaa cctcatttta atggggctgc caggcgcagg taaaggaaca caagctgaaa
    41821 aaatcattga tgcttatggt attccgcaca tctcaacagg agatatgttc cgcgcagcga
    41881 tgcaaaacga aacagctctt ggcctggaag caaagtctta tatggataaa ggtgcattag
    41941 ttcctgatga agtaacaaat ggaatcgtga aagagcgact agctgaacca gatacagaga
    42001 aaggcttctt attagatggc tttccacgta cgctagatca agcaaaagct ctggacgcaa
    42061 tgctaaaaga tttgaataaa aaaattgatg ctgtcatcga tatccatgtt ggtgaagaaa
    42121 tcttggtcga acgtctagcc ggccgattta tctgcagcaa ttgtggagca acttaccata
    42181 aaattttcaa ccctacaaaa gttgaagaca catgtgatcg ttgcggtggg catgaattct
    42241 atcaaagaga agatgataaa cctgagacgg ttaaaaatcg tctggctatc aacatcaaaa
    42301 atagtgaacc aatcttggct tattataaag aacaaggttt gctaaacact attgatggtg
    42361 ctcgtgaaat cgatgctgta tttgcagatg tacaaaaaat cattgaaaaa tagcacgatt
    42421 gcccgtagcc gacttgcatt atgcagttac tcttgtcaag ttcaataaat tatgatagaa
    42481 tatgtcagtc cgacttctag agaatcctct agatgatcca ttttgagaat tttgaggtgg
    42541 gaactgcagt ttccgccatt ttatcgtgtg aaaatgcgaa acaagtacaa ggaggtactg
    42601 tgcgtggcaa aagaagatat gattgaagtc gaaggtacag tcgtcgaaac tttgccgaat
    42661 gcaatgttta aagttgaact agaaaacgga caccaagttc ttgctactgt ttcaggtaaa
    42721 attcgtatgc attacatccg tatcttacct ggtgacaaag taacggttga attgtctcca
    42781 tacgatctta accgtggccg tattacttat cgctttaaat aattgtactc cgtaaaacta
    42841 caggaggtat tatcatgaaa gtaagaccat cagtaaaacc aatgtgcgaa cattgtaaag
    42901 taattcgtcg taaaggacgc gttatggtga tttgcccagc aaatccaaaa cataaacaac
    42961 gtcaaggata attggaggtg ctataaatat ggctcgtatt gcaggagtag atattcctcg
    43021 tgataaacgt gtagtagttt cacttactta tatctatggt attggtaaca ctactgctaa
    43081 aaagatctta gctgatgctg gtgtatctga agatgttcgc gttcgtgaat taacgaatga
    43141 acaaacagat gctatccgtg cagaagtaga taaattaaaa gttgaagggg atcttcgtcg
    43201 tgaagtgaac ttgaacatca aacgtttgat ggaaatcggt tcttaccgtg gaatccgtca
    43261 tcgccgtgga ttgcctgttc gtggacaaaa cacgaaaaac aatgcacgta ctcgtaaagg
    43321 cccagctcgc gctatcgctg gcaagaaaaa ataattctta agtgaaggag gttaaaactt
    43381 catggcagca aaaaaagtga atcgtaaacg ccgtgtgaag aagaatatag aagcaggtat
    43441 tgcacatatc cattctacat tcaataacac tatcatcatg atcactgata ctcacggaaa
    43501 tgcattagcg tggtcatcag ctggttcatt aggtttcaaa ggaagcaaaa aatcaactcc
    43561 ttttgccgct caaatggcag cagaaactgc tacaaaagca gcaatggaac acggattaaa
    43621 gactgttgaa gtaacagtta aaggacctgg ttctggacgt gaagcagcaa ttcgttcatt
    43681 acaagctaca ggtttagaag tgactgcaat tcgtgacgtg actccagttc ctcataatgg
    43741 tgcccgccct ccaaaacgcc gtcgtgttta atgagtgccg ctcattttga gttttatcag
    43801 taacgtcatt gaacaagaca cttttcgttt tgaaaggggt aaagataaga atgattgagt
    43861 tcgaaaaacc aagaatcgca aaaattgatg aagaaaaaga ttatggcaag ttcatcgttg
    43921 aacctcttga aagagggtat gggactactt tagggaattc cctacgtcgt attttattat
    43981 cttctttgcc aggtgctgcc atcactaata ttcaaatcga tggtgtactg catgaattct
    44041 ctaccatcaa aggtgttaga gaagacgtca ctcaaatcat cttgaacatt aaaggcttag
    44101 cgctgaaaat gtatggccaa gaagaaaaaa cccttgaaat cgatattacc ggacctgcta
    44161 cagtaactgc tggcgatatt atcgttgata gtgatgtaga aattcttaac aaagatatgt
    44221 acatctgtag tgtctctgaa ggagctacgt tccatgctcg cttaacagtg aaacctggac
    44281 gtggttatgt tcaagcagat gaaaataaaa aagaagatat gccaattggc gttcttccag
    44341 tcgattcaat ctacacacct gttcgtcgtg tgaactatca agttgagaac acacgtgttg
    44401 gacaccgtga agattttgat aaattgacga tggagatttg gacagatggt tcaattgaac
    44461 cgttggaagc aatgagtttg tctgcgaaaa tcatgactga acatttggat atttttgtga
    44521 acttaactga tgaagcaaaa aatgctgaaa tcatggtcga aaaagaagaa acacaaaaag
    44581 aaaaaatgtt ggaaatgacg atcgaagagt tagacttgtc tgttcgctct tacaattgtt
    44641 tgaaacgtgc aggaatcaat actgtacaag aacttacaaa taaatctgag cctgaaatga
    44701 tcaaagtccg taacttagga cgtaaatcat tagaagaagt taaagcaaaa ttgcacgact
    44761 taggtttagg tttacgtaaa gaagattaaa accttttacg aaggagggaa accaacgtga
    44821 gttatcgtaa actaggacgc acatctagcc aacgtaaagc gatgttgcgt gatttaacaa
    44881 ctgatttatt aatcaacgaa cgtattgtga ctactgaagc tcgtgcgaaa gaagttcgct
    44941 caactgcaga aaaaatgatc actttaggta aacgcggaga tttgcatgca cgtcgtcaag
    45001 ctgcggcttt cgtacgtaat gaagttgcca gcgtgcgtga agaaaatgag gacatcgtca
    45061 ttgaatcagc tttacaaaaa ctgttcaacg atattgcacc tcgttacgca gaacgtcaag
    45121 gcggatacac acgcattttg aagacagaac caagacgcgg tgatggtgca ccaatggttg
    45181 tcttagaact tgtctaaaat cacactaata acatcacttt atagatgatt cttttagagt
    45241 gttatgatgt tggaagatat ttttccgagt ctagctcagc gctgctcctc aagcgaatat
    45301 cgcttgggga gtaagcactc atcataaagt gtttttttat accttcaatt acctgtcatg
    45361 acagatatgt ttgaaggcat aaaaaaacat tttaagcgag aaataattga aaattttgtc
    45421 tttttttgat agtgttagta ggaactttag gatgaagaag gagtaatcat ggagccaatt
    45481 attgaattag aaaagataaa ttataaatac cagccagatg atcttcgccc cgcattgaaa
    45541 gatgtctcct ttacaattga taaaggtgag tggatcgcta ttattggaca caatggttca
    45601 ggaaaatcga cacttgccaa aacgatcaat ggattgcttc tgccagaatc agggatcgtg
    45661 aaagtgggaa atcaaatatt ggatgaagaa aatatttgga cgatccgaca gatggttgga
    45721 atgatttttc aaaatccaga caatcagttt gttggttcga cagtagaaga tgacgttgct
    45781 tttggtcttg aaaatcaagg gattcccaga gaagaaatgc tagtgcgtgt gaaagatgca
    45841 cttgagaaag ttagaatggc tgagtttgct tcacgcgagc ctgctcgttt atcaggaggg
    45901 caaaaacaac gtgttgccat tgccggcgtg gttgccttac gacctgatat cattatttta
    45961 gatgaagcaa ccagtatgct agatccagaa ggtcgtgaag aagtgatctc tacgatcaag
    46021 aagatcaaag aagaaagtca attgaccgtt atatctatca ctcatgatat tgatgaagca
    46081 gctaatgcca atcggatact agtgatgaga caaggcgaac ttgtccgtga aggtacacca
    46141 aaagaaattt tttctgctgg tcctgaactg atcgacttag gtctagatct accatttcct
    46201 gaaaaactga agagcgcact gaaagaacgt ggggttgatg tgcccagtga atatatgaca
    46261 gaagaaagga tggtggattg gttatggaca tccgttttga acaagtagac ttcacttatc
    46321 agccgaatac accatttgaa caaagagcct tatttgacat caatatgacg atcaaagaaa
    46381 acagttatac tgcattagta gggcataccg gaagcgggaa atcaacctta cttcagcatt
    46441 tgaatgcgct tgttaagcca acaagcggta cagtccatat tggagaacga gatattcagc
    46501 cggatacgga taataagaat ttaaagccca tccgaaaaaa agttggcatc gtctttcagt
    46561 ttccagaagc acagctattc gaagaaacgg tagcaaaaga cattgctttc ggtcctaaaa
    46621 actttggtgt cagcgaagaa gaagcactag tcctagcaaa agaaacatta gaacaagttg
    46681 ggctggatga aagctatttg gaacgttcgc catttgaact ttcaggaggg caaatgcgta
    46741 gagtagcaat cgctggtgtg cttgccatga ggccggaagt acttgtattg gatgaaccaa
    46801 cggcaggact tgatccccag ggcagaaaag aaatgatgga gatgttttgg cgtcttcata
    46861 aggaacagca gatcactatt gtattagtta cgcatttaat ggatgatgta gccaattttg
    46921 cagattatgt ctatgtgttg gaaaagggac gaatcgttaa tagcggggag ccgcaagagg
    46981 tctttcaaaa cattgaatgg ctaaaagaaa aacaactagg cgtacctact gccaccgagt
    47041 ttgcagaaga attaatggct aaagggatga actttgctac cttgcctttg acagctgaag
    47101 aattagcaga cgctatcgtc cattatgctg gaggaaatgc ccatgatgaa taaattgata
    47161 tttggtcgtt atatgcctgg agattccttg atccatcgat tggatccccg agctaaatta
    47221 ttagccagtt tttattttat cggaatcatt tttttagcaa ataattggga aacgtacctt
    47281 ttgttggcat ttttcacatt actttctgtc ttcttgtcaa aagtagattt gaaatttttt
    47341 atccgaggca ttcgcccatt gatctggcta atcctcttca ctgtagcttt gcaggtcttg
    47401 tttacaagtg gcggagaaac ttattggagt tggggtgttt tccatatcac tgaatttggt
    47461 gtgatgaacg gcctctttat tttctgtcga ttcgtgttga tcatttttat gtcgactcta
    47521 ctcacgctta ctacaccgcc tttggaatta tcggatgcga ttgagtactt gcttcgtcca
    47581 ttgaaagccg tacggttccc agtccacgaa atttcattga tgctgtcgat tgctcttcgt
    47641 tttgtgccta cattgatgga cgaaacagaa aagatcatga acgctcagcg cgctcgcggt
    47701 gttgattttg gtgaaggaaa cctagttcag aaaatgaaag cagtcattcc tttgctgatt
    47761 cctttatttg tcagcagctt caaccgtgcg gaagatcttg cgactgctat ggaagcaaga
    47821 ggctacaaag gtggggaagg aagaacgaaa tatcgtgtat tgcattggca taatagagac
    47881 acgatggtta tcattgcttt tgtattatta actgtgctac tgatcttttt aagaggataa
    47941 acgttcagtg ggccgctatc tattcttttc ttgctgatct gtttgcaaga aaggatgcaa
    48001 gcagtgtatg acaagaaata ttagggtctg tggcagacta aggtcacagg cctctttctt
    48061 ttatctgaaa agaaagaacg aaaaaatttt atagaaaaat cattattcca gataaccttt
    48121 taggaacaaa ggagagaaaa acatggtacg ttacaaagca atcattgcgt acgacggaac
    48181 aaattttaat ggattccaaa aacagccaaa tgggcgtact gttcaagaag aagtagaaaa
    48241 aacattacaa aaaatggcaa atggaaaaga aatcacggtc tttggttcgg gaaggacaga
    48301 tgccggagta catgcgatcg ggcaagtaat ccattttgat tatccagagg agcgtccgtt
    48361 agaacgaatg cgtttcgcgc tagataccca gtcaccagag gatattgctg taagacaagt
    48421 agaaattgtt tcagaagact tccacgcaag atatttggtc aaagaaaaga cgtatcaatt
    48481 tcgagtggat atagggaaac cacgcagtcc ttttcgacgc cattatgcaa gttattttcc
    48541 ttacccactt gatttggaaa aaattcagcg ggcgcttcct gatttattag ggactcacga
    48601 tttcacctct ttttgtgcat caggaagctc gatagaggat aaaatacgta cgatctacga
    48661 ggctaagatg gaggtaaatg aaacaaaaga cgaattgttg tttacattta ggggaaatgg
    48721 cttcttgtat aagatgatac ggatcttagt aggaacgctt ttgaaaattg gcaatggccg
    48781 attgcctgaa gatagtatcc cagatattat tgcgaaaaaa gatcgtaatg cagcaggacc
    48841 tacagcacac cctgaaggac tttatttgta tgaagtgaaa tatgaataag aggttatgat
    48901 agaagtggtc agcttcaaga aataagaagg tatttacgaa aattacttct caaaattttg
    48961 caaaatttcg gcttattttc gaagaagcta cttctggaac accgtttaag aaagaggtcg
    49021 tgagcctgtc atttaactct gagtcacaaa gagcaatttc aaaaaacagc ttctcatctt
    49081 tgatgaatat cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta
    49141 ttttttctgt aaccaaaaaa cgatggaacg ttgttttgat tgcccttggt gcggacagtc
    49201 tgaacaggtt ccatcgtttc tttattttct acgtcttctt ctgtgtgtgt ttcgtggttg
    49261 ttcttctatt gctggatcaa tcgtgccata aaaggggcga ttgcggtcaa ggtaccagac
    49321 ataaagaata aacaatgcaa tacataggac aaaaaggatt gcacctatcg taaatccttc
    49381 aggcaagtaa ctgaaagtga cagtatgttt acctgctgga acttttatca tcaagaatgc
    49441 gtctttgaaa ttgctgacct tgactggttt cccatcaatt ttagctttcc atcctttgtc
    49501 ataaggaata gttgtcacca acatggaatc ttcagcggta tttacagtcc cagaagcttt
    49561 tctgccagtg gcttccattt cgacaccttt ttctttgatc tgattcattg cggcttgata
    49621 ggctacaaca tctagaccaa cgactttagg ctccatgaaa cttatttctt tcgtcccata
    49681 aaaacttgca gtaaatgtca ctgttgtctc ttgaggataa tagccaagat catagtattg
    49741 accagaaatg ttgatttgcg tttttcgcga tgtaccattg acagtgatcg tcgcactaga
    49801 actttctaat tgcgcaaaat tggttgggaa caaacttaag taagcttgtg tatttgcagg
    49861 cacatggact tcccaagtga gctcttttgg ctggttatct gctgtttctg agtaagtgac
    49921 gccagtcgtt gtctttgtga tcgtcgtatt caactgattc ttcaaagtag gtgtatagaa
    49981 tgtaaaatac tgttcattta gaccagacaa tgtattgatc aagtttgtct gactggtcaa
    50041 attatctgtc actggctgct caacatcatt aacggacaac ggtgcagtaa atgctagtgg
    50101 caatgcattg acattctgat acagtgtata gtcgccgctt tgaccagctt ggcggaagcc
    50161 atatttactg aacgtgcttt cgtttttaga aatgttatat ttgattcctg taaacccatc
    50221 catcagcaaa gtattattgt tataacggat attcaaattt gtccctcttg aacggaaacc
    50281 taatttatcc aggtaagagg aagaattacg atttcttata gaagaaaaca aactgatacc
    50341 actgtaacca tagttgatcg aatcgtttgc agatactgga tccagatttt ccaagcggta
    50401 aaacgagtcg gaatcttttt ttgtttcatt tacaagagct ttcaagtcag gataaggatc
    50461 agtatataaa ctgcgggaag cataattcca atcatcaaga atgccatgga tcatactgtt
    50521 cgtattgacc agtgcttcag cagacatgat caataataac aatatactca gatgattgaa
    50581 tgaaagtttt ttatgctgat aaaatcccac agcaaaagca taaatcccta agaaaaccac
    50641 tgtcaataca aaggaagtca tcgtcacata ggtgtagctt ccttcaggtt tgatgcccca
    50701 tgccaccgca aagagagcag ctacgaccaa aatgattcct aacaacagcc caccatcgtc
    50761 ttgttctatc ttttcccatc cttttcctgc aagcaggagc actaagaaag agaacagata
    50821 ggcataacgg aataaaaaca tattcggtgc atgcatacca tgccagaaca aattcaatgg
    50881 aacaagataa aaacttgcga taagtatggc gaaaagactg ccgtacaaaa atttattttt
    50941 caacggtact ttccgactgg caaaataaaa cagacagagg actaatggta gcagacctgc
    51001 gtaaacgaac ggaatcgatc cgtattttgt cgtgtcataa acaccaatca tatttttcat
    51061 gattagatcc agataagaag tcgcttctgt tttcaacgta gtgatctgac tcagtgcctc
    51121 gccatttgac cgaagatcca gcactgctgg caatacaatg atcattgaag cgccgcctgc
    51181 cagtaaagaa gtgataccat aaggaacaat cgttttttta tattctgacc agtttgtcaa
    51241 tagacgggcg ataaaatata agaaagaaaa tacgccaatc ataaaaccca tataaaaact
    51301 ggataaaaac aagagtaaat aactgataaa taaaagtttc ggccgtttaa gatccataac
    51361 acgatgaatc cccaaaatca ctaatggaag ataaacaaat gcatccagcc acatgatgat
    51421 ctccgaatgt gcagtgataa atgagatcaa tgcgtaactg acgctaagtg caacatgccc
    51481 ccagcgagga atcttgaacg tacgtgcaag aaaccaaaaa gccaatccgg cacagccgac
    51541 cttaagcaaa gtcagaacat acagtgcatc tggcatcatc tggtttggaa aaaagaacac
    51601 cagtggcgtg aagatcccgc ctagatagta agaaattaaa gataaataat tcaatcctag
    51661 agaagcattc catgtataaa aaatactttg ctttccaaga agaacatttc ggaagctggc
    51721 atgaaaatta gaaaactgtg aaaaggcatc acttgccaaa atacttctgc tgcttccagg
    51781 atagattccg atacttagat aaacaagtgc taaaatcaaa aacggaatca ggaaactagc
    51841 tgctgcgtag cgtccgtttt ctctaaagaa tgactttaaa ttttttttca tatttatttt
    51901 ccaccaaatt tctatgaagt tgtattcagt ttatcatatc cttgtttttc tctgcttaaa
    51961 aagagtctag ttttcacaaa aaaataaaat ttagaataaa taacttcata atttgttcgt
    52021 ataacaaaaa taaacgcaaa aaaagggtag gaatcaaaag tcccaccctt aaaaattttt
    52081 attaaataaa aaaccgttca ctatctgaac ggtccaagta tcattcaatt aaacgcgttc
    52141 aacttttcct gatttcaaag cacgagttga cacccaaact tttttaggtt ttccgtcgac
    52201 cataacgcga actttttgta agttaggttt aacagtacgt tttgttgagt tcatagcgtg
    52261 tgaacggttg tttccacttt ttgtcttgcg acctgtaaag taacaaactt ttgccatggt
    52321 aatttcctcc tttgccttga tttggagcaa tagaataatt cagctcatac cagactaaca
    52381 tatcatatag aatgggaatt tgcaagtaca ttttcataga tacaattgac aattgagaag
    52441 aataattgta aattaaacaa ggttatacct gaaattttgc aaggtttttg agtactttgg
    52501 gtaactgcct tttatttcaa gttgcgctat gataaaatat gatagaagaa aaatgggagt
    52561 tttttacccg ttaaggaggc tcattcatgg ctgtaaaaat tcaaacgtca gctggaacca
    52621 ttgaaattac caatgatgta attgcaacag ttgttggtgg cgccgcgaca gatgtgttcg
    52681 gtgttgtagg aatggccagc aaaaatcaaa ttaaagataa tattactgag attttgcgta
    52741 aagaaaatta ctcaagagga gtagttgtcc gccaagaaga taatggtatt gctgtagatg
    52801 tttatacgat tatcagctat ggtacgaaaa tctctgaagt ttcccgcaac gtccaagaaa
    52861 aagtgaaata caatctagag gcattattag gcgtaactgc caattcagtt aatgtctttg
    52921 tacaaggtgt tcgtgtactg ccagactagg caggagactg gctggtaact cagcagtcga
    52981 tctgaaggag gattatctag gtgagtgtaa cagaaataag tgcaagccag ttccaggaaa
    53041 tggtccaggc aggtgcgaat cgtctgcaag taaatgcaga atacgtcaat tcattaaatg
    53101 tattccctgt gccagatggc gatacgggaa caaatatgaa tctatctatg actagtggag
    53161 ctaaggcagt agtagattca acctcagaaa aagtaggaga attagcagca atgctttcaa
    53221 aaggattgct gatgggtgcg cgcggaaatt ccggcgttat tttgtctcaa ttgtttcgtg
    53281 gattttctaa gcaaattcca gatgttgtct cattaaatgc ttctgatctt gctgcagcct
    53341 tcactcatgg agttgaaact gcgtataaag cagtaatgaa accagtagaa ggaacgattt
    53401 tgacagtagc tagagaagca gcgaaagctg gagaaaagaa agcaaaaagt actgatgatg
    53461 tcgttgaagt aatgacagct gttgtaaaag gagcaaagcg tgctttagct aaaactccag
    53521 acttgcttcc agtcctaaaa gaagtcggtg tcgtagacag tggagggcaa ggactgctgt
    53581 ttgtttatga gggcttttta agtgcattga atggagaatt ccaagcggat gaaacatatg
    53641 aaccttctcc agcagaaatg gatgatatgg tcaatgcaga acatcatcgc agtgtccaag
    53701 gtcaaatggc gacagaagat atccattttg gttactgtac agaaatcatg gtaaaaatcg
    53761 gagaaggacc tacagtcgat agtacattcg attacgaaga attccgtaac tatttagatg
    53821 gtataggaga ttctttactt gtggtcaatg atgacgagat catcaaagtc cacgtgcata
    53881 cagaaaaccc aggagaagtc ttgaattatg gacaaaaatt cggttcatta gtcaaaatca
    53941 aagtcgacaa catgcgcttg cagcatgaga cgattttgga acacgatgaa gaagtgaacg
    54001 agtttgcgaa aaaagaaata ccacgtatcc cgtatggtat cgtagcgatc gctgctggta
    54061 aaggcgtcca agagctgttt gaaagtttag gcgctaatta tgttatcagt ggtggacaaa
    54121 caatgaatcc aagtacggaa gacattgtta aagcgattca agaagtaaac gcagataaag
    54181 tgattgtctt gccaaacaat aagaacatct tcatggcagc tgatcaagca gcagaagtag
    54241 cagatatccc agtagcagtt gttccttcaa gaacgatttc ccaaggattg acagctatgc
    54301 tttcattcaa tgatcaagct tctttagaag aaaacaaaga aacgatgaca gaaatgttgt
    54361 ctagcgttgt gagcggtcaa gtcactcacg cgatcagaga tacctcaatt gacggtgtag
    54421 agatcaaaga aggagacttt ttgggcatga tcgatggaaa aatcctgatc tctaacccag
    54481 atatcacagc aacagcgtta agtacactag aacaaatgat caatgaggac acagagatcg
    54541 taacgatctt ggcaggtgat gaaggaacag ttgaacaagc aaatgaattt gctgagaaac
    54601 taacagaaaa acatcctgat ttggaaatcg agatccacca aggagatcag cctgtctatc
    54661 cttatctatt ttctgctgaa taatttctgt gtcagaatat ctttctaaca cagtattcat
    54721 tcataaaagg ccttcggtta gtgatcaggt atgatcgctg accaagtcct ttttttgtta
    54781 aaggagggag gaaaaattta tgcgttcttt agatgatcca atcactatgc tggcaggagt
    54841 cggagaaaaa agagcagcta gtcttgccag cttgggcatc caaacgattg aagacttact
    54901 gacttattat ccttttcgct acgaagatat tcaggaaaga aatctaaacg agatccagga
    54961 tcaagaaaag gttactttga aaggaatcgt agtctcgcct cctgtgatga atcgatttgg
    55021 ttataaaaaa agccgattgc aatttcgtat gatgcaagaa catgatgtgt tcaacgtttc
    55081 tttttttaat caaccttatc taaaagaaaa agtcatttta tcggaggaaa tcgccgtata
    55141 cggtaaatgg gatgcaaagc gtaaagcctt gaacgggatg aagattttag gttctcaaac
    55201 aatggatgac ttttcgccga tatatcacgt caacaaatca attcgtcaaa cgacattagt
    55261 tgatctaatc aaaaaagggt ttcaagaata cggcacattg attgaagaaa atctgccaaa
    55321 caaccttgtg gagaaatatc gactgcttga ccgagcttct gctgtaagaa gtatgcattt
    55381 tccaaaagac cacgaagaaa accatcaagc caaacgacgt gtcgtttttg aagagttctt
    55441 tttatttcaa atgcgtcttc aaggattgaa aaaagcagaa aaagcagaaa cgaatggttt
    55501 ggagatcctt tatgatgtcc aaaaattgaa acaatttact caaaagctac cttttgaact
    55561 gacaaatgca caaaaacgtg taacgaatga aatctgtcgg gatcttcgca gtccgcagca
    55621 tatgcagcga cttttgcagg gagatgtagg tagcggaaaa acagtggttg ccgcgattgc
    55681 gttatacgct accgttacag caggtttcca aggtgcgttg atggtgccta cagaaatctt
    55741 ggcacaacaa catatggaaa gcttgcaaca gctgtttgat cccaatgaag taaccatcgc
    55801 attgattacg gggtcaacga aagcaaaaga acgacgtgag ctccttgaaa aactagagca
    55861 aggggaaatt aacgtcgtga tcggcacaca tgcattgatc caagatggag tcgaatttca
    55921 gaatttaggt ctagttatta cggatgagca gcaccgtttt ggcgtgaacc agcggaaagt
    55981 acttcgtgaa aaaggctggc gaccagatgt cttatttatg acagcgactc cgattcctag
    56041 aacattagct attacagcat atggtgagat ggatgtatct atcattgatg aacttccagc
    56101 tggacgtatc ccgatcgaaa cacgctgggt aagaacacct caattggaca gtgtactgga
    56161 ttggacgaaa aaagaactgg caagaggaca tcaaatgtat gtcatctgtc cgctgattga
    56221 agaatcagaa gcattagatg taaaaaatgc agtggaaatc tatgaaaaac ttcgtgaact
    56281 atttgcacca aaatatgaag ttggcttgtt acatggtaaa atgaagaatc aggaaaaaga
    56341 agtaatcatg gaagccttca aagacaacca gatgcagata ttagtttcga ctactgtaat
    56401 tgaagtaggg gtaaacgtgc cgaacgcgac cgtcatgctg atcatggatg cggatcgatt
    56461 tggattggca cagctgcacc aacttcgtgg acgtgttgga cgcggaagtg atgcttccta
    56521 ctgtatctta gttgctaatc ctaaaaatga actaggtgtg gaacggatga aaatcatgac
    56581 agagaccacc aatggttttg tactaagcga aaaagatctg gaattacgtg gtcctggtga
    56641 agtatttggc ttccgtcaat ctggtctgcc tcaatttgcg attgctgact tggtgacgga
    56701 tggaaatgtt ttggaggtag ccagagaaga ggctgcagcc ctttggcaaa taaaggattg
    56761 gcagatgctt cctgagtatc agcctttagc gcaaagcctc caaatagaaa atcaggataa
    56821 tcgttatttc gattagcaga ctgtgctata ctttatactg atgacggaaa aaggagtgga
    56881 aacaatgaaa attgccgtag atgcaatggg cggagatcac gcacctcaag caattgtaga
    56941 aggcgtggct ttagcgcagc aagattttcc agaagtagaa ttcttacttt acggaaaaga
    57001 agcagaaatc aagaaatact taacaaatga aaaaaacatc acgattatcc atacagacga
    57061 aaaaatcaat agtgatgatg agccagtaaa agcaattcga cgaaaaaaga ctgcatcaat
    57121 ggtccttgct gcacaagcag tgaaaaacgg tgaagcagat gctgtatttt cagcagggaa
    57181 tacaggcgcg ctactagcag cagggttgtt catcgtagga cgtatcaaaa atatcgaacg
    57241 ccctggcttg atgtctacct tgccagtagt agggaaagaa ggtgccggtt tcgatatgct
    57301 ggatcttggc gctaacgcag aaaacaaacc agaacatttg ttgcaatacg gtattttagg
    57361 ttctttttat gcacgtaaag tccgaggtat cggacgtcct cgtgtcgcac tcttaaacaa
    57421 cggaacagaa gcaacaaaag gtagtgaagt gacgaaaaaa gcctatgaac tccttcagaa
    57481 tgaaacaagc ttgaatttta ttggaaacgt agaagctcgt gagctactca atggtgtggc
    57541 tgatgtagtg gtcacagatg gatttacagg caacgctgtt ttgaaatcta ttgaaggaac
    57601 agcaatgaat atgatgaatc tattaaaatc tgctattcta aatgaaggga tcaaaggaaa
    57661 aatgggcgct atgcttttaa aagacggctt acgttctttg aaagcagaaa tggattattc
    57721 caaacatggc ggtgccgttt tgtttggctt gaaagcacca gtcattaaaa ctcatggagc
    57781 aacaggcccc gatgctgttc gctatacgat ccgccaaatc cacacaatgc ttgagacaga
    57841 tgtagttgga caattagtcg aacaatttga aaaaagcgaa gaatagtatt tggatatctg
    57901 aagcgatccg ttccattgaa aaaaaggtgg acattcctga aaaatgccag taaaattagc
    57961 catggtgtag gtaattgaca agtgtatgat tcttggaggt gaaaaagttg actcgcgaag
    58021 aagtatttaa caaagtagcg aaaattattt caaatcattt tgagatagat accgataaag
    58081 tgacggatga attgaacatc aaagatgatt taaaagctga ttcaattagt attatggaat
    58141 tcgttttaga gcttgaagat gaattcggta cggaaatttc agatgaagac gctgaacaaa
    58201 ttgaaacagt cggtggcgca gtagattata tcagcagcca tcttaaataa tttcaaataa
    58261 aagcaaagaa ggataaaaag ctgcatgcag ctttttatcc ttcttttttt aatctttttg
    58321 acacgtaaaa gtcatttttc tgataattct ggcgataaac agaaattatg ttgcaaagta
    58381 aagcggtttt ctatataatt attaataatt cattacacaa agataagaat aacctttgtt
    58441 ataaaacgat ttattctgtg taatgtcctt ttttattaag aaaaacttcc atttaggaag
    58501 cagagagggg tattcgattg tccgataacc aattattaga agttcagaac ctacatacag
    58561 gattccgact caaagatgac tattacgatg cagtagatga cgtttcattt actttagaca
    58621 aaaacgagat tttagcaatc gttggggaat ctgggtgcgg gaaaagtacc ttggctacta
    58681 cgattatggg attacttgat cctaataaca caaaaattac aggtgagatt ttatataacg
    58741 atctgaattt aatcgacctg aacgaaacgc tctataataa aatccgcgga aatgatatcg
    58801 gaatgatttt ccaagatccg ttgtctgcat taaatcctct catgagaatc gaagaccaga
    58861 tcaaagaagg actttcctat cacacaaaga tgaatgcaga acagcgtcaa gctcgtgcac
    58921 tagaattgct agaacaagta gggattccta atcctgcgag agttggacgc caatatcccc
    58981 atgaactatc aggcggtatg agacaacgtg tcatcatcgc aatcgcaatc gcctgcaaac
    59041 ctccaatcgt cattgcagat gaaccgacga cagccctaga tgtaaccatc caagcacaga
    59101 ttcttgattt actgaaagac cttcaggaag aaacaaaaac agggatcatc ttgatcactc
    59161 atgacttagg agtcgtagca gaaatggctg atcgagtggc agtgatgtat ggcggacagt
    59221 tcgttgaagt agcaggtgta aaagaactgt ttgatcatcc taagcatcct tatacacgct
    59281 ctttactgaa ctctatacca caagaaggaa atcatgatgc agaactccat gtgatcgaag
    59341 gtgtcgttcc ttctctgaaa aacatgcctc gtaaaggttg tcggtttgca ccacgtattc
    59401 catggatacc agcaagcgat catgaagaag agcctatcct tcatgaagtc gcaccgaacc
    59461 acttggtacg ttgctcctgc tataagcatt tccactttag agacgaaaaa ggagaggtgt
    59521 agatgacaga attaatcaca atcaaagacc tgaaagttca ttaccctatt cgcagtggat
    59581 tcttcaatcg agtaacggat catgtatatg ctgtagatgg tgtggatttt attatcgaaa
    59641 aaggaaagac atatggttta gtgggagagt ctggctctgg aaaatctact acgggaaaag
    59701 ccgttgtggg attagaaaag gtaacagccg gacaaatcat gtatgaagga aaagatgtaa
    59761 cgaagcgaag caaccgcaaa aaaatgggtt ataacaagga tgtgcagatg atcttccaag
    59821 attcaatgtc cagtttgaat cctaaaaagc gagtgttgga tatcattgct gaacccatcc
    59881 gaaattttga acggttaagc gatcaagaag aaaagaaaaa ggtaaaagga ctgctagata
    59941 tcgttgggat gccggaagat gcgctatata aatatcctca tgaattttca ggcggacaac
    60001 gtcaacgtct aggagtagcc cgtgctgttg ctaccaatcc aaaactgatc gtagccgatg
    60061 aacctgtatc tgctctggat ctatctgttc aagcgcaagt attgaatttc atgaaacgaa
    60121 tccagcaaga atacggcctc agctatttat tcatttcaca tgatttaggt gtagtaaaac
    60181 acatgtgcga caatatcgca attatgtaca aaggtcgatt tgtagaaatc ggtacaagag
    60241 aagacattta taatgacccg cgacatatct atacgaaacg tctgctttca gctattccgc
    60301 aaatcgatgt agaaaatagg gaaagccaca aagaaaatcg acgaagagta gaacaagagt
    60361 atatccaaaa ccaaaaagaa tactatgatg cgactggtcg agtctacgat ttgcgtacga
    60421 tcacaactac acacaaagtg gcgttgaaag atggaggtgc aagctaatgt ggaaaacgat
    60481 tctgcgacgt gttttattga tgatcccgca agttattatt ttaagtgttc tgatcttctt
    60541 attagcccaa gcgatgccgg gggatccatt taccggtttg atcaatccaa atcaggatcc
    60601 ggcagtgatc gaacagatgc gacaagcagc tggcttgaat gacccatggt atgtccagta
    60661 cttccgttgg atcggaaatg ctttgcaagg cgattttggt caaagtttct tatacaaacg
    60721 ctctgttgct gacttgatcg gcgaacggat catcaacact ttatatctat cgatcttgac
    60781 agttgtcctt acttatttga ttgctgtgcc tctggggatg cttgctggcc ggtatcaaaa
    60841 ttcaatcttg gataagattg tcgtaatcta caacttcttt agttttgctg ttcctttatt
    60901 tatcttcggc ttgatcatgc tatttgtttt tggttatcgt ttaggctggt tcccaacaag
    60961 tggatcacaa acactaggtt tgcaaggtgg atttatcact caatggatag accgtttgaa
    61021 atatattctg ttaccatcaa ttacccaagc atttttggcg actgccgtca caatccaata
    61081 tctgcgaagt gaagtaatcg attcgaaatc gctcgatttt gtcagaacag cccgttccaa
    61141 aggggtaccg acgaataaag tattcagtcg acatattttc cgaaatgcag cgttgccgat
    61201 ggcttctcaa atggggtatg aaatcacttc gttgattgct ggttctgtag ttatcgaaaa
    61261 gatttttggt tatccgggag tcggaaaact atttattgat tccatcggcc aacgggacta
    61321 taccgtgatc acatccttag tattgatttt aggaatcgcg acgctagtgg ggacattact
    61381 ttcagatatc atcatgagta tcgttgaccc gcgtattcgg attcaataaa accaatcaga
    61441 aaggagaatg gatcgatgag tgaaaaaaac aatacagcag ttcaagaaag tattcctcct
    61501 atggggatac gaatgattgc tcgagaattt aaaaaagata aaattgctat tttttcatta
    61561 ggtttgctag tggttttatt attagtgatc tttatcggtg cgatgctgac cgatcaagac
    61621 aaagtgatgt atgttagtat cttcgacaaa tacgctgcac caggaacagt ttcgacacaa
    61681 ggacaaaagt tcattctggg agcagatgaa ggcggacgtg atgtattagg acaattgatc
    61741 ataggtgcta gaaactctgt tacgatcgga tttgcgatca cgatccttac ttcgatcatc
    61801 ggggttggat tagggatcat ctctggctac tacggaggga tcattgacaa catcttgatg
    61861 cggatcgttg attttatcat gattctaccg atcatgctga tcattatcgt cttcgtatcg
    61921 attatttcca gatacaatgt ctggtccttt atattcatca tgagtgcatt ttattgggta
    61981 gctaaagccc gattattccg aagcaagaca ttatctgaag caagaagaga ttatgtcagt
    62041 gcctcaaaaa caatgggaac caatgatttt aaaatcatgt tccgcgaaat catgccgaat
    62101 ctaagttcat taatcattac taatttgacg atgaactttg cggcaaacat cggtatcgag
    62161 acaactttga ctttcttagg tttcggcttg ccggcaaatg tacctagttt aggtacattg
    62221 atcggttatg caagtaacgg agaagtctta gtgaatcggc aatggatctg gttacccgca
    62281 tcaatcctta ttttagtttt gatgttgagt atcaattatg ttggacaagc attcaagcgt
    62341 tctgcagatg cgcgccaacg gttaggctag tatagaagcg aagggggaaa taggaatgaa
    62401 gaaaacgatt tttggatttg cagcgctgat gtctgctgtc gttcttgcag catgcggggg
    62461 cggaggtaca gatacctctg gaaacaactc tggaggcaac ggcaataaca aagaggaatt
    62521 aacttttcca attgcaacaa aaaataatga tgatgcaatc gaagacggcg aattagaagc
    62581 tgcggtcgca acggacagtc agtttaaagg attgttccag tgggagtttt accaagattc
    62641 atatgatgca gcttttatgg ctccttctca tgaaccgcta tttgcaaacg atgacgattt
    62701 cagaatcaca gacgacggag ctgcaacgct tgatctagat gaagatacga aaaaagcgac
    62761 aatcaaagta aaagacaacg tcaaatggtc agatggtgaa gatgtaacgg cggacgatgt
    62821 gattttccct tacgaaatca ttgggaataa agattacact ggtatccgtt atgacgacac
    62881 tttccgtaac atcgtaggta tggaagaata tcatgatgga agtgccgaca caatctccgg
    62941 aatcaaaaaa atagacgaca aaacagttga aatcgaatat aaagaagtaa acccaagcat
    63001 gcttcaatcg ggtggtggta tctggtcata tgcagcacca aaacatacgt tagaaggtgt
    63061 agcaatcaaa gatatggaat caagcgatca agtacgtaaa aatccagtga cttttggccc
    63121 ttattacatg agtaatatcg ttgcaggaga atcagtagaa tacttgccaa acgagcacta
    63181 ctggaatggt acgcctaaat tgaaaaagat cacgatgaaa tctgtaccga tggcaagtgc
    63241 aactgaagca ttgaactcta aattatatga tatgattttc caaatgccaa cagatactta
    63301 cgatacctat aaagaaattg ctggctatac aaacttaggc cgtgaacaaa cttcttatac
    63361 ttatctagga ttcaagttag gtaaatggaa tgcagataca aagagtgtgg aatacaatcc
    63421 agattcaaaa atggctgata aatcattacg tcaagcaatg ggctatgcat tagataataa
    63481 tgcagtaggt gaacgtttct atgcaggttt gagaagcaat gcgacttcat tgattcctcc
    63541 agtattccag tcataccatg atgatgagat gaaaggattc acacaagatc tagacaaagc
    63601 gaaaaaacta ttagatgatg ctggctacaa agatgtggat gacgatggtt taagagaaga
    63661 caaagatgga aataaactaa caatcaactt tgcttcgatg tccggtgggg aaacagcgca
    63721 accattggca gattactata tccaacaatg gaaagaaatt ggtttggatg tccaatacac
    63781 aacaggtcgt ctgatcgaat tcaattcttt ctatgataaa ttagaaaacg atgatcctga
    63841 aattgatgtt taccaagctg cttggaatac aggaactgat ccaaatccaa gtggactatg
    63901 gggaccaaat gctgcgttca actacactcg ttatgaatca gaagaaaata caaaattgat
    63961 caacgatatc agttcaagca aagcatttga tgaagagtac caaaaagaag catatcaaaa
    64021 atggcaacaa tatgcatttg aagaagcatt tgcgattcca acgttgttcc gtaatgaagt
    64081 attgccagtc aacgaccgtg tcaaagactg ggattggtct tatgatgtac caaacccatg
    64141 ggcaaatgtt tctgttacag cagattcacg ttcataatca ctaaaaatga ccgaaaaagg
    64201 gcgatgtcct ttttcggttt tttgatattt ttctgtttat ttctctaata ttcaggtcaa
    64261 ggcgctgatt tcatgacttc tccaataaac ggtgttcaaa gtccagtttc tcggtattaa
    64321 gtcaaattta tgcaaaaata tggaaagcca ttttcacaaa attttttctt catactcgaa
    64381 actaaacgaa tttttcacaa cttctcgtca atcactagga ttattaaagc tttacttacc
    64441 ttttgaccga accatttcaa atttgacaaa aaaccagtat aataaggaag tatcgaaaaa
    64501 atatccataa aaggaatgtg gaaaatggac aaccagctga caaaagaact aaaagaaaac
    64561 tataacatcg tttttcacga tctaaatttg cttgaacaag cttttaccca ttcatcctat
    64621 gtgaatgagc atcgcaatct gcaattatcg gataatgagc gacttgaatt tttaggagat
    64681 gccgttttag aactgatggt ttctcagtat ttattccgtt tatatcctca tttgccagaa
    64741 ggaaaattga caaaaacacg agctgcgatc gttcgcgaag acagcttgtc gaaatttgcc
    64801 aaagaatgtc actttgatca atatgttttg ttgggcaagg gagaagagaa ttcaggagga
    64861 cgtacgcgac cagcattgct ttgcgaccta ttcgaagctt ttttaggcgc gttatatctt
    64921 gaccagggat tcgacacgac ccatgcattc atcgaaaaag tgatttttcc taaagtcaaa
    64981 gcaggtgctt tttcacatga gatggatcat aaaacaaaac tacaagaagt cttgcaaaaa
    65041 tcaggtgatg tatcaatcga ataccgattg atcaatgaag aaggtccagc tcatgaacga
    65101 gtattttgga tcgaagttta tgtagatgat caattgattg gcactggaca agggaaatcg
    65161 aaaaaattag cagaacaagc tgcggcggaa aatgcattgg cagcactgta aaagtaagtg
    65221 agggaaagct ttgtatttga aacgaattga aatagccggt tttaaatcat ttgcagacaa
    65281 gacagtcatt gattttgaaa atagcgtcac agcagtggtt ggaccaaatg gcagcggaaa
    65341 aagcaatatt acagaggcta tccgctgggt attaggagaa caatctgcta aaagtctgcg
    65401 aggcggaaaa atgccggata tcatctttgc cggttccgat acccgtaagc agctgaatat
    65461 tgcagaagtc acagtgattt tagacaatag tgatcattat ctgccattgg agtacaatga
    65521 gatcagtgta acccgccgtt atcgacggac tggggaaagc gagtttttca tcaataaaca
    65581 aagctgcaga ttaaaagata tccaagaatt gttcttagat tctggattag gaaaagaatc
    65641 gttctcaatc atttctcaag gaaaagtaga agcgattttc agtagtaaac cggaagaccg
    65701 tcgtgggatc tttgaagaag cagctggtgt cttgaaatac aagcagcgga aaaagaaagc
    65761 agaacagaag ctttttgaaa cagaagacaa cctcagccgc gtccaagaca tcatccacga
    65821 attggaagaa cagttaactc ctttggccgc ccagagtgag gcagcaaagg agtttttacg
    65881 gctaaaagaa acactgactc aaaccgatgt ctctttgatg gttgctgaaa tcaagacagc
    65941 aaaaaaagat tgggacaaca aacaagcaca gcttgcgaaa ttcaatctag aattaggcaa
    66001 actatctgag tcgatccaag aacaagaatc cattttggcg aagcagcgta aagaaaatgc
    66061 gcaagccgat cgtctgatcg aaaaaaatca gcaagtatta ttagatcttt cggaaaaact
    66121 gaagcagaca gaaggacaaa aagatgtttt gcaggagcgg acaaagcata cacaaaaaag
    66181 ctcgcaagaa tatcaaactt cattagcaga agcacaaaaa aaggttaaac attttgaaaa
    66241 gcttcaagaa agcttgatga aagcagcagc agaaaaagaa acagagatcc aaaaagctga
    66301 agcaaatctc ataaaaacac agcaagaatt agaaaaatac caaaaatcaa cgaaagaatt
    66361 attggcagaa ttaagagatc aatatgttga tttgatgcaa gaacaagcag ctgtaggaaa
    66421 cgaactgaag tatctagaac gtcaatatat acaagaaaca gcaaaaagca agcagacgtt
    66481 agccaagcaa tcggaagtag aagcatcagt agaccgattg atcttacaaa aagaagaatt
    66541 gacacaaaag caggcgcagc taaaatcatc tttaactgaa acaaaagaga agttagaaat
    66601 gatccaacaa aacgggaaaa agttccaaga agcattagca aaagaacagc ctaaaatgta
    66661 tcaattaatg aatcaagtcc agcagctacg tgctcgtaag aaaagccttc aagaaatcca
    66721 agaaaactat tttggttttt accaaggggt tcgattggtc ttgcagcata aacagcagct
    66781 ttcgggtatt gtcggagcag tggctgaact gatcgatgtt cctgcagatt tcacgttagc
    66841 tatcgaaaca gctttaggtg gggcagccca gcatgtcatc gttgaaaatg aaaaagatgc
    66901 tcggcaagcc atcacgtatt tgaaacagca aagaggagga agagcaacat tccttccact
    66961 gacgacaatc aaaccaagac aattaccggc tcatatattg acacaagcag cagctgtaga
    67021 agggtttata gggattgcca gtgaacaagt cagttatccc gatcaaatcc aaactgtggt
    67081 tcaaaacctg ctaggaacga tccttttagc caaagactta actagtgcca atgcaatcgc
    67141 gcaaacgatc cgctatcaat atcgagtggt ttccttagaa ggtgatgtga tgaatgccgg
    67201 aggatccatg acaggtggag cgaataaacg aggaaaccaa ggcagtttgt ttgtacaaaa
    67261 tcaagaattg aaacagttga ctagtgaatt tgaagaagca gataaacaac tccaagcaca
    67321 agaaaaaaaa gttcaggagc tgcaacaaga aacagctcgt ttagccgaag aacaagaagt
    67381 tttgcgtaca cgaggcgaac aattacgttt tgaagaacaa gaagcgacaa atcagctaca
    67441 aaacatcata aatgaacttg aacgttttga aaaagaaaag caaatctcaa cttttgagac
    67501 acgtgaactg cagcagttta tcgaagatta cgaaaagcaa acgaacgaat tgaaagacaa
    67561 acaaacagat cttgaatcgc aacgacaaaa aatcgacgaa gaaatcaaat cgttaagtca
    67621 agaaagcgac cagatggaag ccagaagagc acaagtacaa agtcaaaaag cacaagaaca
    67681 agcagatctt gctgtcttga aagagcagtt taatcatctg cagatccagc tccgcggtgc
    67741 ccgagtccaa aaagcagagg caaccgaacg tcaagaagcg atagaaaagc agttggcgac
    67801 attgacagca gacttttctg atcatgaagt cacagaagaa agtttggaaa aacaaattaa
    67861 cgaattatct gctcagcgag aaacattaaa agccgagttg gcaaaagcca aagagcagcg
    67921 agatagaagg caaaaggaga tcgataagct tgaagcagtc ttggcagagc gtaatcgtga
    67981 gcaaaaagca cgactgtcgg aacaatccaa attagaagtc caaaaagacc gagctgaaat
    68041 gattttagat aatcatttga cctatctgca gtcagaatat cagctgacat ttgagaaagc
    68101 ttcccaagac tatcaagaaa caaccgatat cgaagacagt agaacaaagg tttcatcctt
    68161 aaaagaacag attgaaaaac tgggaccagt aaacttaaat tcaatcgaac aatacgaaca
    68221 agtcagtgaa agacatacat tcttagcaac acagcgagat gatctgttag cagcgaaaaa
    68281 ccaattgttt gaaacgatgg atgagatgga tgatgaagtg cggacaagat tcaaagaagt
    68341 atttgaagct atccgtcaag aattcaaaat tgtctttcca aatatgtttg gcggcggtaa
    68401 agctgaatta gtactgacgg aaccaactga tttgctgaaa acaggtattg agattgaagt
    68461 acaacctcct ggcaaaaaac tgcaaagtct aagtttgctt tctggaggag aacgagcact
    68521 tacagccatc gcgttgctct tttccattat ccgtgtctgt cctgttccgt tttgtatctt
    68581 agatgaggta gaagcagcgt tagatgaagc caacgtgaaa cgttttggtc gttacttgag
    68641 cgatttccaa gatgacacac aatttatcgt agtcacacac cgcaaaggaa cgatggtcgc
    68701 agcagatgta ctgtacggag tgacgatgca ggaatccggt gtatcaaaaa tcgtttctgt
    68761 acggatggaa gatatcaatg aagaggcgaa aatcaacgaa acgaaagtgt aggaacgaaa
    68821 atgatcaaat tagtagcaat cgatttggac ggtacattat taaatgaaca aaagctgatt
    68881 tcagatgaga ataaacaagc attagcacaa gcaaaacagc aaggggtcaa gatcgttcta
    68941 tgtacaggac gccccttagc tgcgatggcg cattatctgc aagaattagg actggtagat
    69001 gaaggtgact acagcatcac tttcaacggc ggtttggtac aaaaaaatga tactggtgaa
    69061 atcatggaaa agaaagtgat ggaagtatca gatatccaac gcttatacaa actggctcag
    69121 caattggatc tgccactaga tgttttgtct gacaatgtgg ttttacagct gcctagtgcc
    69181 ccaaggaagc aatccttgta caatgtgttg aataagctgc tgcaattcca accagcggat
    69241 ataagcgata ttacagatga atttgtgctt aataaggcag taatcgctta tgaccaagaa
    69301 gaattagatc ctaaaatcaa agaaatacca gcagaattcc atgaaatgta tgagatcatc
    69361 aaaacaagaa gtatgctttt ggaatttatg ccaaaaggtg ttacaaaagc ttatggtatt
    69421 tctttattgg caaaagatct tggtttgaaa caagaagaaa tcatggcgat cggtgatgag
    69481 gaaaatgatt taccgatgat ccaatatgct ggactaggcg tagcgatgga gaatgctgtg
    69541 cctttcgtca aagaagcagc agatttcgtg acagccagca atgaagaaaa tggcgtagcc
    69601 aaagtgatcc aaaaatttgt attagagtag ggggagtcaa atgggatttt ttgataaaat
    69661 caagcgtgct tttactggcg aagagaaaac agaagaagtt gaagtacagg agaagtacga
    69721 caagggttta gaaaagacgc gtaaaacatt tggtgaacgg atgaatgagt tgtttgccaa
    69781 ttttcgaaca gtcgatgaag acttttttga agaattagaa gaaacactta tcggtgcaga
    69841 tgtaggtttt gaaacagcga tacgaattac cgaagcatta cgtcaagaag tgaaactcag
    69901 aaatgcgaaa aaatcggcag aagtccaaaa tgcgatcatc gagaaacttg tggatctcta
    69961 tgaagcggaa ggaatcaatg aagtaaatga actaaatatc caagaagacg gactaacagt
    70021 tattttgttt gtcggtgtta atggtgtagg gaaaacaaca agtattggta aacttgccca
    70081 tcagttcaaa aacgaaggta aaaaagtatt gatggcagca gcagatacct tccgcgctgg
    70141 agcaatcgac cagttagttg tctggggcga acgcgctggt gttgaagttg ttcgtggcaa
    70201 tgcaggaggc gatccagcag ctgtcgtatt cgatgctttg gaaagagcaa agacagagca
    70261 ggcagatgtt ttactagttg atactgcagg ccgactgcaa aataaagtga acttgatgaa
    70321 cgaattagaa aaaataaaac gagtaatcca gcgggaatta ccagaagcac cccaagaaac
    70381 acttcttgta ttagatgcaa ccactggtca aaacgcgatg gttcaagcaa aacaattcaa
    70441 agaaacaaca gatgtgaccg gtcttgtttt gacaaaatta gatggtacag caaagggcgg
    70501 tatcgtactt gctatccgta atgaattgca tttaccagtg aaattggtcg gtcttggtga
    70561 aggaatcgat gacttggagc cgtttgatcc aaatgatttt gtcgttggat tgttcaaagg
    70621 attactaaaa gaagaataac ccatgtctaa aaagcaggag ctgtgacaaa agttgcagct
    70681 ccttgtttga atgattgttt ttaacatagc tgtgtttttg atgccttcat ttttatactt
    70741 atttgtaagc ggttctcaaa caatttcgtt ctttttctta gactttttga ttataattag
    70801 attcatatga attggaggtc acttaatgat gaattttaag caattattat tgcatgtcaa
    70861 tgcgcgccct tttatcgacc aagctcgatt tggtatagaa cgggaaggac agcgggttga
    70921 tcttgcagga aatctagcaa aaaccgatca tccagcaatc tttggcgatc gatcctatca
    70981 cccctatatc caaacagatt ttagcgaaac acaaacagag atgatcaccc ctgttaccga
    71041 ttctattccc gaattatttc agtatctcgc tgctgtttat gatgtgactg ctcgttctat
    71101 accgaaagaa gagatgatct ggccattaag tatgccacct gccttaccgg aaaaagacga
    71161 agagatcatt attgcaaaat taaaaaattt cgaagatgtc ttgtatcgac gttatttagc
    71221 aaaagaatac gggaagcgaa aacagatggt aagcggtatt catttcaatt ttgaatttgg
    71281 cgatgagttg ctaagaacat tgttcagcca tcaggaagaa tttcaagatt tttccgaatt
    71341 caaaacagaa ctttatttga aaacagcgag aaactttatg cgctatcgct ggatgatcac
    71401 ttatttattc ggtgcttcac caatgagtga gaagaactac tttttagatg aatcacatcc
    71461 gcaagaacct gttcgcagta ttcgcaacag tgcgctgggc tatacgaatc atccaaatgt
    71521 gaaagtttcc tatgcttcta tgaaacagta tttagcagat atcgagcgaa tgatcgaaga
    71581 agggaaactt tcggaggaga aagaatttta tacaccgctt cgtttccgag gcggaaagaa
    71641 agtcgcagat ttagcaacaa caggtgttcg ttatattgaa ttgcggaata tcgatttgaa
    71701 tccttatgca agattgggta tcaatccaga gcaagttcgg ttcttacaat tattcctgat
    71761 gtacatgtta tggacagaag aaaaagaaga ctgtgaccaa tgggtagcag aaggtacgac
    71821 tcgaaataac aaagtagcac tagaacaacc atcagatcaa acagaatttc atcaagaagg
    71881 tagagaaatt cttgaaggaa tgaagcaaat gctggttgaa ttggattggt tggattctct
    71941 ttatttagta gaggaagcat tgactcaaat ggatcatcct gaacaaacgt tagcagcgaa
    72001 actctatcaa gaagcacagc tatcgagtca gcaagaagtt gctgtggcat tgggacatca
    72061 atattataaa gaaagccatg aacgtcccta tcagttggcc ggttttcgcg aaatggaact
    72121 ttctactcag atatttatgt tcgatgccat ccaaaaaggt gtccaagtca aagtattaga
    72181 tgagtcggat caatttttgc gtctgcaatt ccaagaccat gtagaatatg tgaaaaatgc
    72241 aaacatgaca agtaaggaca gctatatcgt cccacttatc atggaaaaca aaacagtaac
    72301 gaaaaaagtc ttaaaagaag ctgggttccg ggtaccagga ggcgcagaat tttcatccat
    72361 ggaagaagcg gtaaaagctt atccgagatt tgccgagcag gcatttgtga tcaaacctaa
    72421 atcaaccaat tacgggttag gtatcacgat tttcaaggaa ggagctagtc tggaagatta
    72481 tcaagcaggt ttagccattg cttttcgtga agacagttcg gttttagtag aagaatttat
    72541 gccgggaacg gaatatcgtt tctttgtgat cgacggagaa gtccaagcca tcatgttgcg
    72601 agtccctgct aatgttattg gtgacagtat ccgaacagtg aaagaacttg ttgaagaaaa
    72661 aaatagtgac cctttgcgtg gaacgaatca tcgtgcacct ttagaattga tccaattagg
    72721 tgaattagaa caattgatgt tgaaagaaca agggttgacg atcgaatcag ttccccaagc
    72781 caatcaaatt gtttatctaa gggagaactc aaatatcagt acaggtggtg attcgatcga
    72841 tatgactgat gaattttctg aagcttacaa aaaaatcgcc gtttctgcgg tagaagcact
    72901 aggagctaag attagtggta tcgatttgat tataccagat aaagaaatcg atcctacaac
    72961 tgataaaaaa gcatatggga tcatcgaagc aaatttcaat ccagccatgc atatgcatgt
    73021 ttatcctttt gcaggaaaag gcagaagatt gacgatgaat gtattgaaat tgttatatcc
    73081 tgaagtattt taaaagaaaa agcttttgac agattgtcct atttgatgtc aatctgatca
    73141 aaagcttttt ttgcatgtaa aaatttatgt gttttttcgt tttaaaataa acgatcccag
    73201 aagctttttt tcttttttgg tttttctttt tcagctggcg aagagttttc ttctgggtat
    73261 tttttttcga tatcaatcac aggttcattt actgcttctt ttgctgttaa gagcaatccg
    73321 aattcctcag gatttgcagt gacgtaatcg ttgactacag tgaaacggct attgtttttc
    73381 gttgctagct ggatatattg gttttggaca gaaaggggta gagccccatt caagagtatg
    73441 gaagcatctg gatgtttttt gagttctttt aaaaagtttt ctttgttttt tggttggatc
    73501 atttcagcaa cagtcatact aagatagcag cgttccctga atgtccctaa atatttatgc
    73561 tgttcttcag ggttcactaa aggtgtacca taaagtccct tatccaaatg gctttttaca
    73621 tcatcttgtg ccataaaaaa taccctcctt cttctctttg tctttcttac gattatagca
    73681 tattcccaat aatacctaaa acatatgaaa aagcggttgc ttttgttcaa cgattcactt
    73741 aaaataagaa tgaaaatcat tctcaattag aaaggtggat tggatgcgct acggacgact
    73801 agtagcatta ttagttattt taagtagtat ttcattgttc atcggagtat cgaatgtaca
    73861 attgtcagaa ctgctccagt tagatgggca aagcttacaa atcttgctag tgactcgttt
    73921 gccacgaacg atttgtttga tccttgtggg agcgaccagt agtatttgtg ggttgatcat
    73981 gcaacatttg acccaaaata aatttgtttc accaacgact gcgggcacga tggatagtgc
    74041 gcgtttaggt attttagtgg ctatgatttt cctacctggt gcatccttga ttgtccgatc
    74101 cttgacagca ttttgctttg cttttgcagg aacattgctt tttttatccc ttacgcgatt
    74161 gttcctccag aaaaatcaat tgatgcttcc gttgattgga gtcatgttag ggaatatcat
    74221 tggttcagtt gctacttttt ttgcttatca attccagttg gtacaaaata tgacttcatg
    74281 gcttcaaggg aattttgcga ctgtgatacg aggaaattat gagttattgt atgctgttgt
    74341 tccattgttg ctcttggttt ggctatttgc ttaccgattt acgatcattg gtctgggcga
    74401 atcgtttgca gtaaatctgg gaatagatta ccagaagatg cagtttttag gcattggctt
    74461 agtatcattg gctagtgcag tcatgttgat catggtagga agcattcctt ttatcggagt
    74521 gatcattccg aatcttgtct ctagaatata tggagatcaa gtgcacaaaa caattggcgt
    74581 aactgcttta gcaggtagtt tgttcttagt attttgcgat cttgtcgctc gcgtgttgat
    74641 ttttccttat gaaataccag tcagtgtgat cgttggaatc atcggtgggg ctatcttcct
    74701 ttatcttctg ataaggggac gacgatatgc ttaaaaaaaa gccatctatt tttattggta
    74761 tgcttgttct tgttttattt gttacaggaa tgtacttgac gatccataca tatggaaact
    74821 ggcattttgc atgtgcattg aggagtaaga aaatttttgc atttatcctt gtctcgctag
    74881 ctgtcagcag tgccacaatc agctttcaga caattacgca taaccagttt ttgactcctt
    74941 cagtattggg acttgagtcg ttatatgtcc ttgtccaaac ggtccttttc ttctttatcg
    75001 gaggagtgac gatgcttcag cagacaggta cagttttttt cttattgaac gttgggctga
    75061 tggtcgggct gagtctattg ttatttttct ttcttttgaa aaaaatgaga gcgaatcttt
    75121 ttttattact gatgtcaggg atgattttag gtacgctttt tggtagtgtc agtacctttt
    75181 tacaagtcat catggatccg aatgaatatg atttgcttca aggcagatta tttgcaagct
    75241 ttggcaatat ccagagtcag tatcttttgc ctgcttcttt gatcattatc ggctgctggt
    75301 acctgttatt tcgatatcga catgtgctag acgttttcca tctcggaaat gaacaagcag
    75361 taaacctcgg gatagacaca gatcgttttg aatttttgat tttatgttgt gtcagtcttt
    75421 tgacagggac atcaacggct cttgtgggtc cagttacttt tttagggttt attgtcgcaa
    75481 atatcagtta tcgtgtcttt tctacttatc gtcatggtca gctatttatc ggaagctttc
    75541 tggtagctat gctgtttctg acaggaggac agctcgcagt agagcagatt ttcggctgga
    75601 atacaacagt gagtgtcgtc gttgaatttg tcggaggaat ttattttgtc acaaaattga
    75661 ttcgcgaaag gaagagtatc ctatgattga tttacaaaag gtcaataaac tgtaccatgg
    75721 aaaatcagtg gttaaagatg tacagttaac gattcctgaa aagaaattga ctgcttttat
    75781 cggtccaaat ggtgctggaa agtcaacggt gttgtcgatg atcagtcgtt tgataccaaa
    75841 agatacaggt gaaatctatt tagaccataa cgaagtaaag gcttggaaat ccaatgaatt
    75901 agccaaaaaa ttatcgatcc tacgacaatc gaatgaaata aatgtccaaa tcaccgtgaa
    75961 agaattagta gaatttggac gatttcctta tacgaaagga aaattgacga caaaagacga
    76021 ggaaatcgtt caggaatcac tggaacacct tgggttagaa gaaatagcgg atcaatcgat
    76081 tgacactctt tcaggcggtc aactccaacg tgcgtatatt gcaatggtgc tagcgcaaga
    76141 cacggattat attttactgg atgaaccttt gaacaatcta gatatgaatt ttgcggttca
    76201 aatcatgcag attttaaaaa atttagtaca agaaatcggg aaaacaattg ttattgttct
    76261 tcatgatatc aactttgctg caagttatgc agacgaaatt gttgcaatga aagatggaca
    76321 gttatttacg caaggaacga cccaagaaat gataaaaaaa gatgtattgg atgaattata
    76381 cgaaatggac atacggattt gtgagattga aggccgcaga ttctgtcttt atttctaaaa
    76441 ctaacattag gagagaagag atgaaaaaat tagtagtagg tatcttgatt ctagcatcat
    76501 ttggtttagc agcatgtgga aatagcaaca acaccagtca ggcagacaca aaaaaaagca
    76561 gcacacaaac tgaaactaca ttgacgataa cagatagtaa tggagaccaa atcgaggtgc
    76621 caaataatcc agaaaaagtc gtcgtattcg acaatggttc tttagatacg atggatgctc
    76681 ttggtgttgg agataaggta gttggagcag ctacaagcag ccttcctgag tatctttcat
    76741 cctataaaaa agtagaatca gcaggtggaa taaaagaacc agacttagaa aaaattaatc
    76801 agcttcagcc agatctaatc atcatttctg gccgacaaag agattttcaa aaagatctaa
    76861 gtcaaattgc tccgaccatt ttcctttctt tagatgcgaa aaatccatgg gaatctttcc
    76921 agcaaaatgt cactgcttta ggggagatct ttggtaagca agaagaagct aaaactcaat
    76981 tagaggaatt atctagtgca atcgatcaga cgaaaaagaa agcagaagct actgacaaaa
    77041 aagcactagt cacacttgtg aatgaagggc aattatcagc ctacggatct ggttctagat
    77101 tcggtttcat ccatgattta tttggctttg aacaagcaga tgatcaaatc gaagcatcca
    77161 ctcacggtca aagtgtttct tatgaatatg tgctggaaaa aaatccggat atcttatttg
    77221 tagtagacag aacaaaagct attggtggag acgacagcaa agatgatatt tctgccaatg
    77281 aactggtagc acaaacgaat gctggtaaaa atcagcagat catctccctt gaaccagatg
    77341 tctggtattt aagcgggggc ggtttagaat caatgaaact gatgatcgaa gatgtgaatc
    77401 aagcatttaa atagcataaa taacagagga ttaaactctc atactatgta acaataatgt
    77461 ttcttacatt cttaaatagc aagagcctat cctcaaagaa gttatcaaaa accatccgta
    77521 aaatcgtatt gatgatttta cggatggttt ttatttattt gagaaatctt ttttcaacgt
    77581 gaattcatta tctacatcat acgggttgat tctagaatgg ggagtggcaa aaaatagtgt
    77641 gatccatttt ttcagcatca agatcgcctc ctttgatttg aatcaaaggt acaaagcgaa
    77701 acttagataa aacttaaatt tagatatttt tattttgtac cgatctcttc tttaaacgat
    77761 gttccatctg ctgcttctcg gcaataagtc cactagacta gaaaatatga gaagctattt
    77821 tctgtccagc gttcttatta ctcaaagcaa atcgcagttg tcacaatctc ttctaaacga
    77881 tgttccatct gctgcttctc ggcaataagc ccactagact agaaaatatg agaagctatt
    77941 ttctgtccag cgttcttatt actcaaagca aatcgcagtt gtcacaatct cttctaaaca
    78001 atgttcaatc agctgacctt cggtattagc tcaaagcact gatttcacaa cctctattta
    78061 ggcatgtgtc tcagcaagcg gttgatagtt gatgatctgc atttttcgat aaaaatcggc
    78121 gggaagctta ctccaccgtt ttaataattg atagaaataa ctctcttctg ctttgatttt
    78181 atactcgctt aatatcaatc caaaactatt cgtttttttt gaagctaatt ttttataaat
    78241 atccaatgct ttggttttat cttcattgac aaagagtgtt tttacttcaa tataagaacc
    78301 ctcgatattt tgtgtttctt cgataaaata gatgtttttt atatattcct tcatagtgat
    78361 tcctccaaag aagtctttta tttgataagt ttactctacc gaagagttgt taataatccg
    78421 tgaacaaaaa gtaattcttt ttccaatagt tgttaaaggt tttttatttt ttatagtatt
    78481 ttttgttatt taagaaagga ataaggttaa acaaataaca ggttgctttt tgggtctttt
    78541 tccgttcaag aaactgaacg aagaaaaggg aaagttgtct cttttgtgat aagagaaatc
    78601 ataataaacg aatgacttac tttccaataa attgagaaca gtcagaacca gacaaattag
    78661 ttgcatctga tgaataaagt gattattcta tgacatgagg tgatacagat gaaattagaa
    78721 gtgacaaaag aagcacaaga agtattgaag aataaattag aagcagacga tcaactttta
    78781 ttagatatcg aaaacggtga cggtccattt gcagaaagcc aagtcagttg ccaattggat
    78841 acggcatttc gattgatcat tgtcaaaaaa gatacacaaa cagatctaag tctttattct
    78901 gtagtggctg atacaccagt tggaccaatc aaaatcaaag acagtgcaat actttacatg
    78961 gatgatccat ccacacttgc tttagaacca acttataata gtttacaatt aaaaggacca
    79021 agcggcttga gaaaaggcaa cttgcaagtt gttcgaaaag actagaggga taaaatggga
    79081 aaattggcga tcatcagcga cctacatgtg gacatcaata aattcggcga atcagagctg
    79141 atgcagcttt ggcaagtttt gcaaaagcac aagatcactc ggcttcatct agccggagat
    79201 acggctaata aagtagaccg ttgcctagct gttgtcgaat ttttcgtcaa taaaggatta
    79261 tctacgacat ttcatttcgg caatcacgag ttggcagatg tgcccaatga acagatgatg
    79321 gaccattttc cagacccaca ttttttaaat gaacggtata ttgctttaaa tgagcagacc
    79381 gttcttttag ggatgaatgg ctggtacgac tatcagtttt ccgaattgaa agattacgag
    79441 gcaatcgtac gaatgaagcg tttgtattgg tatgatcggt tcatccagcg tgggaaaaca
    79501 gatctcgagg tcaatgcaga aatgcttgca gctgcaaaaa atttgctaga ccagctggaa
    79561 gcaaaaaaac ttgaggtgat tttatccact catttcgttc ctaaacgggc atttatcatg
    79621 tatcaatctg ctccttatga gcgttggaac aaattaaatg catttttagg atcagaatca
    79681 ttcggagaat tacttgaccg ttattcaaat atcaaacaag tagtttttgg ccatacgcat
    79741 cgtcgctttg aagataaatc catcggtcac acgatttaca gctgcagacc ttttggttat
    79801 tattatgaat ggcagctgac ccgagatttt gtcttgaaag aacagttgct agacagctat
    79861 gatcctatga aattacgtgt cctcttgcgt gcccatcacc cagcttttca ggcctatcaa
    79921 acacaacatt tgcaagagga atttgaacaa gcgatgacaa tcgttccgta ttgagacagc
    79981 attagtaatg tgtaaaagaa aataccttgt aaaacataag gataagtaag agcagtagat
    80041 ccatttatcg tggatatgct gctttttttg cggaaaataa tcagcgaatg tttatttgat
    80101 cggatgattt gtaactcgca gagtactaga tgcaagcgtg tattcttttt ttgaacgata
    80161 atcacaaaaa aaaata
//
LOCUS       DBGZHO010000006        75915 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.006, whole genome shotgun sequence.
ACCESSION   DBGZHO010000006 DBGZHO010000000
VERSION     DBGZHO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 75915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.006"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(99..3377)
                     /locus_tag="ACN3HL_000581"
     CDS             complement(99..3377)
                     /locus_tag="ACN3HL_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HHC8005487.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3648..4193)
                     /locus_tag="ACN3HL_000582"
     CDS             complement(3648..4193)
                     /locus_tag="ACN3HL_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHC8005488.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(4205..4897)
                     /locus_tag="ACN3HL_000583"
     CDS             complement(4205..4897)
                     /locus_tag="ACN3HL_000583"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HHC8005489.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(4916..5200)
                     /gene="macP"
                     /locus_tag="ACN3HL_000584"
     CDS             complement(4916..5200)
                     /gene="macP"
                     /locus_tag="ACN3HL_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HHC8005490.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(5213..5776)
                     /locus_tag="ACN3HL_000585"
     CDS             complement(5213..5776)
                     /locus_tag="ACN3HL_000585"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HHC8005491.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            6004..6666
                     /locus_tag="ACN3HL_000586"
     CDS             6004..6666
                     /locus_tag="ACN3HL_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HHC8005492.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            6790..7986
                     /locus_tag="ACN3HL_000587"
     CDS             6790..7986
                     /locus_tag="ACN3HL_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HHC8005493.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(8087..9463)
                     /locus_tag="ACN3HL_000588"
     CDS             complement(8087..9463)
                     /locus_tag="ACN3HL_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8005494.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(9500..10366)
                     /locus_tag="ACN3HL_000589"
     CDS             complement(9500..10366)
                     /locus_tag="ACN3HL_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HHC8005495.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(10455..11480)
                     /locus_tag="ACN3HL_000590"
     CDS             complement(10455..11480)
                     /locus_tag="ACN3HL_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHC8005496.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(11498..12172)
                     /locus_tag="ACN3HL_000591"
     CDS             complement(11498..12172)
                     /locus_tag="ACN3HL_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8005497.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(12356..13249)
                     /locus_tag="ACN3HL_000592"
     CDS             complement(12356..13249)
                     /locus_tag="ACN3HL_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HHC8005498.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(13323..15020)
                     /locus_tag="ACN3HL_000593"
     CDS             complement(13323..15020)
                     /locus_tag="ACN3HL_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HHC8005499.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(15013..16326)
                     /locus_tag="ACN3HL_000594"
     CDS             complement(15013..16326)
                     /locus_tag="ACN3HL_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HHC8005500.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(16326..20595)
                     /locus_tag="ACN3HL_000595"
                     /pseudo
     CDS             complement(16326..20595)
                     /locus_tag="ACN3HL_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333417.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
     gene            complement(20893..21411)
                     /locus_tag="ACN3HL_000596"
     CDS             complement(20893..21411)
                     /locus_tag="ACN3HL_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HHC8005501.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(21413..22030)
                     /locus_tag="ACN3HL_000597"
     CDS             complement(21413..22030)
                     /locus_tag="ACN3HL_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HHC8005502.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(22027..22881)
                     /locus_tag="ACN3HL_000598"
     CDS             complement(22027..22881)
                     /locus_tag="ACN3HL_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005503.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(22878..23789)
                     /locus_tag="ACN3HL_000599"
     CDS             complement(22878..23789)
                     /locus_tag="ACN3HL_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005504.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(23830..25164)
                     /locus_tag="ACN3HL_000600"
     CDS             complement(23830..25164)
                     /locus_tag="ACN3HL_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8005505.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            25372..26202
                     /locus_tag="ACN3HL_000601"
     CDS             25372..26202
                     /locus_tag="ACN3HL_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HHC8005506.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(26446..26695)
                     /locus_tag="ACN3HL_000602"
                     /pseudo
     CDS             complement(26446..26695)
                     /locus_tag="ACN3HL_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26886..27080)
                     /locus_tag="ACN3HL_000603"
     CDS             complement(26886..27080)
                     /locus_tag="ACN3HL_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005507.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(27585..27770)
                     /locus_tag="ACN3HL_000604"
     CDS             complement(27585..27770)
                     /locus_tag="ACN3HL_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005508.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(28620..28961)
                     /locus_tag="ACN3HL_000605"
     CDS             complement(28620..28961)
                     /locus_tag="ACN3HL_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HHC8005509.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(28961..29191)
                     /locus_tag="ACN3HL_000606"
     CDS             complement(28961..29191)
                     /locus_tag="ACN3HL_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HHC8005510.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            29478..29816
                     /locus_tag="ACN3HL_000607"
     CDS             29478..29816
                     /locus_tag="ACN3HL_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005511.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(30021..30583)
                     /locus_tag="ACN3HL_000608"
                     /pseudo
     CDS             complement(30021..30583)
                     /locus_tag="ACN3HL_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(31315..31896)
                     /locus_tag="ACN3HL_000609"
     CDS             complement(31315..31896)
                     /locus_tag="ACN3HL_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8005512.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(32079..32705)
                     /locus_tag="ACN3HL_000610"
     CDS             complement(32079..32705)
                     /locus_tag="ACN3HL_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HHC8005513.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(32727..34058)
                     /locus_tag="ACN3HL_000611"
     CDS             complement(32727..34058)
                     /locus_tag="ACN3HL_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HHC8005514.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(34213..34614)
                     /locus_tag="ACN3HL_000612"
     CDS             complement(34213..34614)
                     /locus_tag="ACN3HL_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HHC8005515.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(34700..34906)
                     /locus_tag="ACN3HL_000613"
     CDS             complement(34700..34906)
                     /locus_tag="ACN3HL_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005516.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(35001..36503)
                     /locus_tag="ACN3HL_000614"
     CDS             complement(35001..36503)
                     /locus_tag="ACN3HL_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HHC8005517.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(36521..36976)
                     /gene="argR"
                     /locus_tag="ACN3HL_000615"
     CDS             complement(36521..36976)
                     /gene="argR"
                     /locus_tag="ACN3HL_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHC8005518.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(37074..37691)
                     /locus_tag="ACN3HL_000616"
     CDS             complement(37074..37691)
                     /locus_tag="ACN3HL_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHC8005519.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            37912..39285
                     /locus_tag="ACN3HL_000617"
     CDS             37912..39285
                     /locus_tag="ACN3HL_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8005520.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            39360..40472
                     /locus_tag="ACN3HL_000618"
     CDS             39360..40472
                     /locus_tag="ACN3HL_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8005521.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(40544..42181)
                     /locus_tag="ACN3HL_000619"
     CDS             complement(40544..42181)
                     /locus_tag="ACN3HL_000619"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HHC8005522.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(42349..42957)
                     /locus_tag="ACN3HL_000620"
     CDS             complement(42349..42957)
                     /locus_tag="ACN3HL_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHC8005523.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(43341..44492)
                     /gene="queG"
                     /locus_tag="ACN3HL_000621"
     CDS             complement(43341..44492)
                     /gene="queG"
                     /locus_tag="ACN3HL_000621"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HHC8005524.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(44511..45263)
                     /locus_tag="ACN3HL_000622"
     CDS             complement(44511..45263)
                     /locus_tag="ACN3HL_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005525.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(45404..46354)
                     /locus_tag="ACN3HL_000623"
     CDS             complement(45404..46354)
                     /locus_tag="ACN3HL_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HHC8005526.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(46355..47194)
                     /locus_tag="ACN3HL_000624"
     CDS             complement(46355..47194)
                     /locus_tag="ACN3HL_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HHC8005527.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(47191..47937)
                     /locus_tag="ACN3HL_000625"
     CDS             complement(47191..47937)
                     /locus_tag="ACN3HL_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HHC8005528.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            48175..49545
                     /locus_tag="ACN3HL_000626"
     CDS             48175..49545
                     /locus_tag="ACN3HL_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8005529.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(49600..50496)
                     /locus_tag="ACN3HL_000627"
     CDS             complement(49600..50496)
                     /locus_tag="ACN3HL_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHC8005530.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(50610..50780)
                     /locus_tag="ACN3HL_000628"
     CDS             complement(50610..50780)
                     /locus_tag="ACN3HL_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005531.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(50777..51454)
                     /locus_tag="ACN3HL_000629"
     CDS             complement(50777..51454)
                     /locus_tag="ACN3HL_000629"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HHC8005532.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(51545..52450)
                     /locus_tag="ACN3HL_000630"
     CDS             complement(51545..52450)
                     /locus_tag="ACN3HL_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HHC8005533.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            52625..54079
                     /locus_tag="ACN3HL_000631"
     CDS             52625..54079
                     /locus_tag="ACN3HL_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HHC8005534.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            54095..55126
                     /locus_tag="ACN3HL_000632"
     CDS             54095..55126
                     /locus_tag="ACN3HL_000632"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HHC8005535.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            55133..56320
                     /locus_tag="ACN3HL_000633"
     CDS             55133..56320
                     /locus_tag="ACN3HL_000633"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HHC8005536.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            56476..57858
                     /locus_tag="ACN3HL_000634"
     CDS             56476..57858
                     /locus_tag="ACN3HL_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HHC8005537.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            57830..58216
                     /locus_tag="ACN3HL_000635"
     CDS             57830..58216
                     /locus_tag="ACN3HL_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005538.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(58416..59084)
                     /locus_tag="ACN3HL_000636"
     CDS             complement(58416..59084)
                     /locus_tag="ACN3HL_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HHC8005539.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(59273..60070)
                     /locus_tag="ACN3HL_000637"
                     /pseudo
     CDS             complement(59273..60070)
                     /locus_tag="ACN3HL_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(60351..61730)
                     /locus_tag="ACN3HL_000638"
     CDS             complement(60351..61730)
                     /locus_tag="ACN3HL_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8005540.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(61905..63074)
                     /locus_tag="ACN3HL_000639"
     CDS             complement(61905..63074)
                     /locus_tag="ACN3HL_000639"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHC8005541.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(63049..64200)
                     /locus_tag="ACN3HL_000640"
     CDS             complement(63049..64200)
                     /locus_tag="ACN3HL_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHC8005542.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(64160..65521)
                     /locus_tag="ACN3HL_000641"
     CDS             complement(64160..65521)
                     /locus_tag="ACN3HL_000641"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HHC8005543.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(65518..66519)
                     /locus_tag="ACN3HL_000642"
     CDS             complement(65518..66519)
                     /locus_tag="ACN3HL_000642"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HHC8005544.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(66535..67230)
                     /gene="dapD"
                     /locus_tag="ACN3HL_000643"
     CDS             complement(66535..67230)
                     /gene="dapD"
                     /locus_tag="ACN3HL_000643"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HHC8005545.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(67236..67952)
                     /gene="dapB"
                     /locus_tag="ACN3HL_000644"
     CDS             complement(67236..67952)
                     /gene="dapB"
                     /locus_tag="ACN3HL_000644"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HHC8005546.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(67949..68830)
                     /gene="dapA"
                     /locus_tag="ACN3HL_000645"
     CDS             complement(67949..68830)
                     /gene="dapA"
                     /locus_tag="ACN3HL_000645"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HHC8005547.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(68833..69633)
                     /gene="dapF"
                     /locus_tag="ACN3HL_000646"
     CDS             complement(68833..69633)
                     /gene="dapF"
                     /locus_tag="ACN3HL_000646"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HHC8005548.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(69620..70879)
                     /gene="lysA"
                     /locus_tag="ACN3HL_000647"
     CDS             complement(69620..70879)
                     /gene="lysA"
                     /locus_tag="ACN3HL_000647"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HHC8005549.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(71094..71264)
                     /locus_tag="ACN3HL_000648"
     CDS             complement(71094..71264)
                     /locus_tag="ACN3HL_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005550.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(71365..71928)
                     /gene="efp"
                     /locus_tag="ACN3HL_000649"
     CDS             complement(71365..71928)
                     /gene="efp"
                     /locus_tag="ACN3HL_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HHC8005551.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            72356..73273
                     /locus_tag="ACN3HL_000650"
     CDS             72356..73273
                     /locus_tag="ACN3HL_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HHC8005552.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            73286..74431
                     /locus_tag="ACN3HL_000651"
     CDS             73286..74431
                     /locus_tag="ACN3HL_000651"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HHC8005553.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            74602..75060
                     /locus_tag="ACN3HL_000652"
     CDS             74602..75060
                     /locus_tag="ACN3HL_000652"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HHC8005554.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            75219..75689
                     /locus_tag="ACN3HL_000653"
     CDS             75219..75689
                     /locus_tag="ACN3HL_000653"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HHC8005555.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(75742..75857)
                     /gene="rrf"
                     /locus_tag="ACN3HL_000654"
     rRNA            complement(75742..75857)
                     /gene="rrf"
                     /locus_tag="ACN3HL_000654"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        21681 a        15944 c        13428 g        24862 t
ORIGIN      
        1 aaaaagatag aaggaagtga gacatctatt ggtctcattt ccttctattt ttactttcct
       61 cagtcaattg ttttacatca taaaaggaga aattccactt atttttttcg ctgtttcatg
      121 acataaacaa ctacaccgat taacaaaatt cctccagcta atgctagcaa cgggttatta
      181 aattctcccg tttttgggag tccttgagtg ccattttttt cactttcttt tgctgtccta
      241 tccggatgag aaggttttcc atttggtttt ccatttggtg attcatttcc tggattttct
      301 ctttctggtt tgtcatttcc cgggggcaca tcggcagttt ctcgcacagt gatcgctttt
      361 tgctgggtaa cagattctgt atgagcagac catttttccc catcaaatat ttccgaacga
      421 taagtgactt ctagcgtata ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta
      481 gaaaattgag cacttgactg tgtttcaacg atttggatct tttctgggaa ataacgcata
      541 tcttcaaaga caggcgttcc ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc
      601 ttcagttcaa tgatatttcc ttctgcattc tccgccacac catttgcttc ttgtataata
      661 atcggattat tttgttcatt tggttttgtc tgatttggtt cttgtacgat tgcatactct
      721 ggatattccg aagacggtga ggtttctccg tcaaaaatag cacctacaga taatggaaga
      781 ccatccactc tttccttttc tgtttgacga ttccccggtt taatctgcat cagtccatga
      841 acatggatac ttccattttc atagcgcgta acaggctgct gaccttcttt cgaacatgta
      901 tttagagact cgatccaatc ttttgatatg gtatgtccaa gagtattttc tgattgtttc
      961 tctcgttcat tccaatagta gttcaacgag tggtagattt gatcttcgtt ttgattcaat
     1021 gggcggatct gctctctcat ctcaagattc tctgttcgga aagataagat accagaagca
     1081 tggtagtctg tgtttcctgc tgaagaggta taaagagcca cattatatga accgttatta
     1141 aaacttgtac tgctattgac gataatatct gttccgctat tggaatcgat tcctttcgca
     1201 agattttcga aagacaaact attgatcaat tcatgagggc ccgttaaaga agaaccgccc
     1261 attttgaatc cattaccgtt accttctccc tcaattcctg gtacccagcc gtttcgataa
     1321 gcaactgagt ttttgatgat tacttttccg atcgaacctg tttcattttt agcaaaaagg
     1381 tcccaaccgt catctgcatt atgatacgcg atacaaccgt caaatacatt tccttctcct
     1441 attgtcagtt tggccgcaaa tccatcggca tcttcaaatc ctggatcggc attttcaaaa
     1501 gatgtacagt tcttgactaa gttatgcgcg ggccatgctt cgaaaggatc atttgagcta
     1561 ccgctgattt ggattcctgt atttccattc cgataagcat gaatctcttc gatcaaatta
     1621 tgatttccag aaatctgtaa tcctttttgc atagctgcac tatttgtaat gtcaaaccct
     1681 cgtaaacccc agtagtgact gaacagtgtc atcccatttc cagttccttt aaaatcaagt
     1741 acaggacgct tgttttctgg atttttctct gcaatcaact gaatcgggtt ttctcttgtc
     1801 ccgttaacgc cttttggaat cgtcaatcct ctttcgaagg aataagttcc aggcgccatg
     1861 acgattgtct gcccagcata tgcgtatctc aatgcttgtg tcagagataa tggattttgt
     1921 ctgcttccgt ttcctgcatc tgacccttct ggtgttacat aaactgtcga atatttaggt
     1981 ttacggtagt ccactgtatg aagaatctct tttgtttcat aactagtcat ctctacgtat
     2041 tcttctggcg gatagttttt atctggcgta aaactgaaag taaattcgtt cgttccttcc
     2101 atcagttttg tctgataatc aaattcccga ttcgcagtga tagccaagtt ttttgcgttc
     2161 ttaagcacct ctcctgttgc tttattttta attgtcaata atccgtcagc atttgctcta
     2221 aaggacatag tatgatcttg gtttcctgaa tgattactag aggtcacagt gtaaatcgga
     2281 tcaatcaagc gagtaggtct ttcttgccca ggaggatctg tcgcaggatc tgagtaagca
     2341 acttcgattc cttctacctt gatcgtcata ttccttgctg cagcaaatcc tgcataaata
     2401 accgattcat ctgaagcgta taatttttcc cagtcataca tgatgtcaga agccatttct
     2461 tctcctgttt caggatcgta ataatatgcc tctaaaccag tattcgtttt tttcatctct
     2521 acgtccagtt tagtaatcga gttcgtggcc ggaaacagat tcccatgacc gtttccgaat
     2581 atattataag aacctgtttc tttttccaag aaccctgctg aagtctctaa aggtgttgtt
     2641 tccactgaga cactcccagg agctggcgca gcttgcggat cttcagatga tattcctgtg
     2701 attgcccgtg tccccaatcc aagtcgcatc gtatatttgc tgccgctcgt gttgaccact
     2761 tcttgtctat ccgagtccca gacatattcg atccgactgc ctagtatggc aaatgaattt
     2821 gaataaaatg cctgcccaaa caaatgattt tttggtactg cgtctcttac cattaaagca
     2881 aatccttctt gggcattcgt ataggtccaa gattctattt cgatcgtcgc ccgcatccta
     2941 aagttgatgt ctttggggat tgcttgataa taataggtca ttccatctga tccgcttgac
     3001 tggaattttc cgccgttatt cgtggaagag agccgcacgc cgtcttctaa tggttcaatg
     3061 gcatacctac tagcacttgt gctttctccg aaaacaaccc ctttccactc ttcatttgct
     3121 tcttcagatt gcttttttgt cttttcattt tctgattctt tcatcatagg atcatttcct
     3181 tcttccgtat ccatatcttc actagttctt ggtatttcct ccattgttga catcccttca
     3241 atgttcacgt gtgcattttc ttcgttcaca gactgttgtt cgttagcagc aacttcaacg
     3301 acagaaatta aaaccggggt actgagcata aggagattca tcattagcgc actgtatttt
     3361 atacgttttt ttaacaagtg tattcctccc gtaacaaatt agaaagcgtt tacttaaagt
     3421 attacctaat ttatttttac tgtcaataaa aaacaaaatt ataataagtg tattttataa
     3481 aaagaaaaaa tataacttaa gttgttgata ataaagagat ttattaacgt aaaaagaata
     3541 agttttttta aaataacgta taaaaaagag cataaaacaa agtcgtttgt tttatgctct
     3601 tcttttatta ttttgtgctt tttattttat caaatcactt tgttttttta taaaatttct
     3661 gcgcctagtg tggactcaaa atgtctcaat gcccattcat gtccaacggg atcgaaactt
     3721 gccacggcat ctttgaaaat atggagtttg tatcctagat tatacgcatc gactgctgta
     3781 tgcaacacac agatatctgt acatacgccg gtcaaataaa tatctgtgat ctggcgttct
     3841 cgcaaacgga tgtctagatc tgttccacta aaagcggaat aatgccgttt gtctatccaa
     3901 taaacatttt cctcttgctc atagtcttgg tataaacttt ttaaagagcc gtacaattcc
     3961 cgtccacccg ttcctatcac attatgcgga ggaaataagc ggttctccgg atgaaaggaa
     4021 tcttttggat catgcgcatc aatggcaaaa acgacaaaat ccttttgatc aataaacttc
     4081 tttgtatgag cagtcagctt tttttcaatt acttgtcctg ctgtcccagt agtcagcttt
     4141 ccatcctctg caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc
     4201 ctccttatac gagatgtttg acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt
     4261 cttcgataaa ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac
     4321 gtacgatcaa aaatgggata ttgaactgac gagctgtttg tccaacagcg gctccttcca
     4381 tttcgcaagc taatgcttca gggaaattcg ttaagatttc tttgatttta tctggcgagt
     4441 cgacaaatgt atcacctgta acgatcaatc cttcttttgc gttcaaattc gttgcttttg
     4501 ctgctttaac catttcactg cgcaaatatg tgcttgcttc ataatataga ggcattcctg
     4561 gtaattgtcc tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa gctactttgt
     4621 ctgatataac gatgtcacct acttgtaagc cttcaccgat tccgccagct gaacctgtat
     4681 tgatcaccat gttcacgccg tattgttgga tcaacagact tgtggtaata gatgctaaga
     4741 cttttcctat accggaacgt acgacgatca cttcgtggtt acctaatgaa cctgaaataa
     4801 ataaagcgcc tgcgcgttcc catgataatg gttcgcttag gttctctctc aaaattttta
     4861 cttcttcttc cattgcgccg ataataccga ttttcatctt tttaattcct tctttctata
     4921 taaatgcgat tgctaaaaaa accacacata acattaggat aacaataata agagatttca
     4981 tcaaaaaaga gttccatttg gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg
     5041 gtttattctt tttgctttct ttacgataaa agctggcaat ctttttttct tcttgctgat
     5101 aagctgtttc tgcttttcgc tgttttttta atgactcgct tgcttgtgct tgttgtcgct
     5161 tgcgaagttc gcttcgcgta ataagcggtc ctttggccat aagccgatcc ctctactttc
     5221 ctttggtcaa tagttcccag tattgaatcg cataaatcgt ctttgcatca caaatcaact
     5281 gatctttcat cgcttgttgc gcctcttcaa gagttagatg atacaactcc agtacttcgt
     5341 cttcatcttg tgctaaagga ttctcgacct tctctacccc ttgtgcatga taaatatgaa
     5401 ggacttcatt tgcaaaacct ggtgaaagat acatcgaagt aagatggctc agcgacttcg
     5461 cacgatagcc agtttcttct tctaattctc tagctgctgt catttcggga ttttgtcctt
     5521 ctcctggatc gatttttcca gctggaatct ccaaaatcac tttttctaaa ggttttcgaa
     5581 attgtttgac aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag
     5641 gatgaaatac cagttctctc ttcgaagttc ctccatctgg caaacgaact tcgtctacag
     5701 caacatcaat aatttttccg ctatagattt ctttgcgact gattgttttt tcttcaaatt
     5761 gctcattgtt cagcatatct tctcctgctt tctttgtaat cataactgct tttttttcat
     5821 ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt agattttctc
     5881 taaatataga aaatccttct ttagtccgat actctttata gtagtccgta tgctaaaata
     5941 agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca tggagggttt
     6001 attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt tctctttgtc
     6061 cgaaacaata gtttttcttt tgttctagga cttttattga taggtgtagt tttagttttg
     6121 tggggactct ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc tgcactgact
     6181 gacgaacttg aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt
     6241 cgacaaacaa tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag
     6301 acagccaaac ttaaagcaat cgatctccgc catgatccag tcaaagcagc gaaagcttta
     6361 ttcaaagaat tggtgaaaga accaaaccga ctgcatgaag caagtcagtt tctttatacg
     6421 catctgccga atctagttga tttgacaaat aagtataatg agatcaatga ccatgagatc
     6481 aaaaacaaac agacctatga aaaactagaa gaaagcgcgc agatcatcga ccagctgtca
     6541 gctttaatcg cacaagatta tcaaaaattc gttgctgagg atctagatga tatcgacgta
     6601 gagatatctg ttgcgaaaca gagcttaaag cgtgataata aatatgaacc agaacaaaag
     6661 gattaactct tttgttcata aaagaagact cggaacattc agatgatgtc tggctgtttc
     6721 gagtactttt tctaaagtag agacattcat gtaagaatcg agaacagatt caacaaggag
     6781 gaatttttta tggatcataa accgactgaa acaaaagatg ttacaccagt taacgataca
     6841 cttgaagatt tattgaacaa cccgttttca actccaacag atacgctgac cacttcacaa
     6901 caagcggaga ttgatcagct ccaagagcaa cagacagctg ctcgtttaat tgacaaacta
     6961 ccggcggaac gccaagaaca agctaaacag ctagcagcaa aaatcgatgc taatgatgca
     7021 cagtctgtca tcagctacgg atcggctgcc caagcaaaat taagtgaatt ctcacaatcg
     7081 atgttgaatc atgtgcaagc acaagatatt ggtcctgtag gagattcctt aactgaactg
     7141 atgtatcgtc tccaagaagc caatcctgac gaactgcgtg ccggagaagg gaacatcttc
     7201 cagcgtgtct tcgggaaggt caaacaatcg atctatgaag tgacagcaaa atatcaaaag
     7261 attggtgcac aaattgacaa gatttcagtg aaattagata aagaaaaaga cggtctgcta
     7321 aaagataatc tgatgttaga acagctttac cagaaaaaca aagactactt tgatgcactg
     7381 aatatttata tcgctgctgg agaattgaaa atggaagaac ttcaaacaac gatcattcca
     7441 gaagcgatga aaagagcaga agaaactggc gatcagatgg atgttcagat tgccaatgat
     7501 tacacgcaat tcctagatcg tctggataaa cgtacgcatg atcttcgctt agctagacag
     7561 atcacgatcc agcaagcacc acaaatccgt ttgatccaaa acacaaatca ggccttggct
     7621 gaaaagatcc aagcatctat cgctacagcc attccgctgt ggaaaaacca agtcgtgatc
     7681 gcattgacct tgcttcgtca aaaagatgca gtaactgctc aacgccaagt ctctgaaaca
     7741 acaaacgact tattgaagaa aaattcagaa atgctgaaaa tctcagccat cgaaacagcg
     7801 aaagaaaatg aacgtggaat cgtggatatc gagacccttc aaaccactca aaatgatttg
     7861 atcgaaacaa tccaagagac attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat
     7921 gcagaagtag agcttggaca catggaagaa gatctgaaac aaaaactgtt ggatttaacc
     7981 caatagatca cctttcgctt gttactaaaa caaacgccca acaacagttt attacaactg
     8041 ttgatgggcg tttttcttat ctttcttcta acttctccat tggagtctat ttctcattca
     8101 tcttgctgtg tccatagcca tagccaaaat aaatgatcag tccaataacc attacgatac
     8161 cgaacacgat ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg
     8221 agacgattgg caatagcgga acgaatggca ctttgaattc tccagctttt ggtttgccaa
     8281 acatttttct caacttcagt aagcctagac taacaagcat caaataggcg agcgccatga
     8341 tattcgttag ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat acagctgcca
     8401 caccagcggc ataagtcgct tttttcggtg tacgatgctt ttgatcgatt tctgtcataa
     8461 acttaggaag taagccatcc ttgctgacag caaacagtaa acgagcaagt gaatacatca
     8521 tcgagatcgt taccgtcagt agcgttaaaa ttgcccctac agcgatcacc gcgcccactg
     8581 ttccatgtcc tacatacctc attgcaaaag ccactgggtc attgactcct agttcagtat
     8641 acggaacgat tcctgtcaag atcagcgtca cgatgatgta aaggacagta gcaatcagta
     8701 tcgaaccaat gattcctctt ggcacatctt tttgcgggtt tttgacttcc tcggctgcca
     8761 ttgcaacggc atcaaatccc aagaaagcaa aaaacacaag agctgcacca tctagcacac
     8821 cggaaaaacc aaaaggcatg aatggctgcc agttatcagg tttaacgaaa aatattccta
     8881 caatgataaa caacgcgatg ataccaaatt tgacatatac catggcatta ttcaaacgta
     8941 atgctttctt ggcttcaagc gacacgatgt aagtgacgaa tatcactacg agcaccgcaa
     9001 tcaagtcaat gtatgtacca ttttccggat tgtacccgcc agttaatgct tgtggaagtt
     9061 cggcccctaa acttttcaaa aaaccttgca tatagccaga ccatccggaa gcaacagagg
     9121 aaaccgctag taaaaattcc ccgatcaaca accaccctgt cagccaggca gcaaattcac
     9181 caaatacaac atacagatag gcatatggcc caccaatcac tggcactcgc gaagcaaatt
     9241 ctgcgaaact tagtccagac aaaatgacaa cgattgcagc taagacaaat gaaagtgaca
     9301 gtgctggacc agcattttga ttggccgcaa cccctgtcac cacaaatatt cccgtaccga
     9361 tgatcgcacc aattccaagc atgatcaaat cagacgtttt tagttctttt ttcatctcac
     9421 tcgtatgatt gagattgatc tctttcttac gaaacaaatc cattgaagtt cctccccatt
     9481 ttaggttgga aaacagcgat taaactgttt tcatataccc taaaaggata ccacctaaaa
     9541 tgactaaaag gcaaccaaca ataacataaa tgagctcttt tttcgttttt ctttcgccaa
     9601 ggatgaaaat cccacctaaa gtagagataa tgatccccat ttgtgaaagt gagaagccaa
     9661 cagctaaacc aagtgatttg actgttagaa gcatgcagat gtttcctaag ccccataata
     9721 atccacagat catgtttttc cacacaaact gatcgacttt aactttacgg aaagcaaaga
     9781 agcttgcgcc taagatcatt ccgatacttt gaggtaagat aattgacatc gcatccaaat
     9841 tcgcccagtt gacgatgatg gtatatacac cataaccaat cgtagagaag atcaatgctc
     9901 taaaaccctt accaaaatca agcattttat tatctgtatc tatttttcct tcgtcatctt
     9961 gtcgggcagt caaatacgca ccgcttacaa gaagagctaa agcaataata ccgtatacat
    10021 aatctttcgt ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta
    10081 attgaaaacc agtagacaat ggtagcccta cagaaacacc catgtacttc attccatgga
    10141 actgtccatt ttgtccaaca ctccaagcta agccggataa aaatccgatc aagaaaatcc
    10201 aaggggtgat tacaggacta acaacgaaaa agacaactaa agaaaacaga aatgcaccga
    10261 tcgtcattcc tagtgtttgt tgattggcat cgccaccaat tttaccactt actaaaccaa
    10321 tactacccca tgccaacata gggactaatg ctattaaaat ttccataacc aatctccttt
    10381 tatttcacat gataagaaac ttatcagcga aaacgttaac aacacaagca ctttttttcg
    10441 tttctaacga ttttctaacg tttttcatta taaaaattta agattgggaa aaataaagtc
    10501 attgttgtcc cttttccttc agttgattca gccgtcaaat ggatacctaa tttttcggcc
    10561 agattttttg ctaaataaag tcctaatcct gttgaatgtg ttttgctaag tcgaccattt
    10621 ctcccagtaa atcccttatc aaagatccgt ttcaagtctt ccgctgggat accgatccct
    10681 gaatctttaa ctgaaaggct gactccttgc gcttcctttt ctatgctcac aatgatgttt
    10741 ccgtgatccg gcgtatattt gatggcatta ctaagcaatt ggttgaagat aaaagcgatc
    10801 catttagcat cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg aatatttttt
    10861 tggataaaat aatttgcctg actgcgtatc acaggctgaa tgattccttt tagtccatat
    10921 tcttggatga ggtagtcccg cgagaaactg tcgagtcttg cataatacaa aacttgttct
    10981 acgtattcat cgatttttga taattcattt tctagtaatg tatacttttg atcgtcaata
    11041 tcgaactcga tcgaacgaac tagcaattta gaagcggaaa gtggcacttt gatttcatgg
    11101 acccatgagt caatataatc tttttggtct tgttgattac tgattgctga ttgcattact
    11161 tcttggtgtt cacggatcag ctgattgata tattcttcta ccagtttttc ttcttctgtc
    11221 ctcccaccac tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc taattttccc
    11281 caccatcttc tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa gacgccctca
    11341 atcaaagcta aataagcaat tgtgctcaaa tcaactttga tgtttggcgc cagccacatc
    11401 acaaagatcg tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca ctgatctttc
    11461 aaatatttaa aaaaattcat cttaaccgct catcctttca gggaacgata tatccctgtc
    11521 ctacttttgt ttcgatatat ccttggatac ctgcctgttc gatttttcgg cgtaaccgat
    11581 tgatgttgac tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac agtgctcgca
    11641 gcaatttttc ccgacttaag atctttccat tgtgcttcat caaaataaat aatagacgat
    11701 attcattttt gctcaaatca atgatctctc cgttgatttc catacttccg ttgtcaacat
    11761 tcaacgtaat gccattgtgg ctcatcattt cactagataa ttctgtgtag ttgtaagaac
    11821 ggcgaagtaa tgcattgatt tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa
    11881 aatcatctgc ccccatgttc atagccatga tcatatccat attcgtattc ctgctggaga
    11941 taaaaatgat cggtactttc gatacttcac gtattttttg acaccaataa tagccatcca
    12001 aaacgggaag attaatatct agtaatacaa gctgtggttc ttctctttca aagtctgaga
    12061 acacttgatt gaaatcggtc gttccaaagg tttcaaattg ccatttctca agttcctcca
    12121 tgatcaattg tcgaatgatc tcttcgtctt cgactaccat gatttttgcc ataaaaaatc
    12181 cctccatctt tcttcttgct actacaatat caaagaagcc cttgtgaaac aagttggctt
    12241 acctggaaaa tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc
    12301 gtttgtctct tccaagcagc ttaaatttat tatgttattc ttaataattg gtctattatc
    12361 tgttattttt ctttcgttgt ttttgtcttt taaattttcg ataacaccaa taaccgaaaa
    12421 gcgttagcac tagcaatata cctagaagga gtataagtaa tcgataaaga tggtattttt
    12481 ttgtctgttc tatctttgaa gagacttctt ctgtaaaggg aactcgtctt cctgtcacta
    12541 gtaatcggtg agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact agatcctgct
    12601 tttctctaat tgctaatgta tttgtttttg ttggaaggac aacaattttc tcaacgactt
    12661 cataagcgag catccgacca tacacttcaa gatagaatcg gtcatcttgc tccatttctt
    12721 caagatccgt aaagagtttt ttctcagcaa taccgctatg ggcggtaatc acggaatgtg
    12781 tactctctcc tccagttgga aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca
    12841 aaagatcatt cgtttcatca aataaaggca agctaacatt gattttcgga atatagatgg
    12901 ctccgatcat atgttgttcg taatattctt ttcctggatt ttggacattt ctaaccgctt
    12961 gctcaaaagg atctttgact tgtcccattc ctgggattac tgatgtatga gcaagcgtct
    13021 gatttttctt ttcatgcact gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa
    13081 gctgcttttg ataattctcg atccttcttt gatccaaata attgctgaga gcatctgcta
    13141 aaaatggata tgtaaaaact gcagctccgg caagaaacat cactgccata aataattgta
    13201 ataaaagact gatttgggtt tgaggtctat tacctatttt ctttttcatt ttcttcacct
    13261 tcttatttaa aaaaactgca gcaaccttta taaaaccgat tgctgcagct tatttttgtt
    13321 gcttatactt cagacttcat tttagattta cggtaccagc tgtacgctcc aatcatcaaa
    13381 cttattccga ttagtaagaa tgccaagagc ccgttcccac cagtagcagg aagtgacccg
    13441 cgtttcatat tcggtactct ttctggccct ggattttcta ctcctacgat ctgaatttct
    13501 tcattatagc ttccataaga gatgataaat tcagtaaagg ctgcctcacc tgttggaagt
    13561 acataacctt ctggcgccat ggtctctttc atttgatagg ttccataatc taacccttga
    13621 acctcaaagt atccatttcc atctgcgaca aattctgttg cttgtccgct tgttgcccac
    13681 tcaattctat ctgctcctga ttcataaaca gctaaaggcg actccccttt ataaaatatt
    13741 gcgtattcag aacggtcttc attccacaat tcgaatcttg catctttaag caattcactg
    13801 cttgatgcat catatttttc aaactttctt ccacctgttg tgactttctc tggcggctct
    13861 actccttctt cataatcaaa ttcatcattt cgtccgattt caataaccgc tgtgttgtta
    13921 tggaaatcat ccgcttctag ttctgtggaa accttcaaat tatacgtgat cgttaaatct
    13981 cctccacgtg catctgctaa tctacctaaa gtatctactt tggctactcc attttcttct
    14041 gtcaaaatcg tcacgacaaa cccgttgctt actacttcta ctatataatc ttgtcctttt
    14101 gttaaaatcg tctcgccggc tcgcacttct atttcctgat cataataagt tagaccaact
    14161 gtaggcgtat ctgtgatttt gtaatttttg ataacagcgc ttccgttttc aaggacagaa
    14221 tcgatgaaat aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga
    14281 tcaatataag aaatcgtttc ttgttctcca gcttcattaa taatcgttac ttgtctaagg
    14341 tcgctttcct ctacattcat ctgtttatct gcttctctga tttcgttttt cggatacaaa
    14401 tgcacatctg tattgtatgt gtctttccat gtagaaccat cccacacgcc atccaccata
    14461 tcaggcatca tcactggcat cataacaacc attggagacg cgattctgga aatatgagct
    14521 ggcgaataag tttctaagaa aagatagact ttatctctag aagaaggtgc ttcttccgtc
    14581 acttggacgg tagagaatac cgcttctcca gcttcattcg ttgtttgttt gtcaatactt
    14641 gtcagtcgat attttaaaaa ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct
    14701 tcggcagaat taagaccgtc ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg
    14761 taatatactt ccgttacgtc aaacaaatca aaatcgactc ctggaatatt ttcttcacca
    14821 aaatccgtag aaaccaatcc gctattcggt cgttcttccg gaacagatga gaaacctttt
    14881 ttgtgtaatg taatcgtcac ttcacttggt ttttgtgcga cttcttcggc tttgactagt
    14941 tttccgttcc cgaaaatccc tattcccgca gtaacgagta acagtacact cattcccgtg
    15001 acaatcattt ttttattcat ttttttctcc ccgttctttt tttattaata aaacagcacc
    15061 taacaataaa agaattccta gtaaagaaat caacgttctt gcttcattcg tttgcgggaa
    15121 tacggaccat tttcctgatt gacctggatt gcttggacca ctcggctctt tcggtttgtc
    15181 cgttgtttct tttacggtct cgttataaac acgtggtgtt gcggattcat aggcagagac
    15241 tggaactttc ccggattcta attcagccat ctcctgtccg ttaactacta catattgtgg
    15301 ttggcctttt gcatccaccc aaaattcagg gatgatgacc tcgattctct tacttgcttc
    15361 atccatctcg taaccttcca caccttttaa ttcttcaaaa taataggtgc cagaaggcaa
    15421 gaaacgttgt cctgtcgtaa caaggccctc tttatccgaa atgaatttgc ttacattttt
    15481 gtcattcaaa ggatcattgt ctgctggttt gatccattga tttttcaagt cattagcagg
    15541 agccatatct aaataatatt tccccccttc tatcatctga tatagagcaa aaacagcacc
    15601 ttctaatggt tttccttttt cagttgttcc tctttgacgt ccatacttga agaagtatgg
    15661 atctcttaga taaccgacat ttttaggata gatatgaatc tcttgcagtt cctcggttga
    15721 ttctgtcggg tgataaattg gcaaaatagc agcaattggg atagctgtct gatcgatatc
    15781 aacatccaat ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg
    15841 atcttggttt ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt
    15901 atctttccca gttgttaccg aagtccctat ttggacaagc ctttcttctg tgattagctg
    15961 acggatattg tttctgttcg tttcagcgat ttgctggacg aattctttag gagtcatgtt
    16021 ttcagcagct tttttttcat gataataatc ggtcatgtcg taaatggcaa atgtcgctcc
    16081 atttagtggc accgtctgtg aaatgatatc tgctgtttcc cctgcttcct cagagatagc
    16141 caagccatca ttttcatggt attcaaattg atcgttataa tcgatatctc gaatcatccg
    16201 tttatgcaac acgaattcca cgacatcttc ccctgattct tctgccgaca tcgcatgtgg
    16261 aagaaggact gctgcaagcg gtagtaaaac aagtaattga agcatcaaac acaacagctt
    16321 tttcattacc ttgctccctc ctttttagat tgtctgacaa acaaaccata ggctgctcct
    16381 gcaagcgcca tgaagaatgc agcaagcagg atatagaata atcgtccgga tcctcctgta
    16441 gcaggcaacg gattttcagg atcgttcccg acactaagct gtaatctgat tcgatttgtc
    16501 tccaaaagtt catattctaa ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga
    16561 taatacgaaa tctcaacttt tagtgtaccc gcttcttttc ctggaactac ccgatcattt
    16621 tctatgtcag gttcttctcg ataactaatt tctaaaataa agtaacctgg aagttttcta
    16681 tagctgtcag gtgacttcac ttccttgatc cgatagaccc cttccaacaa gtctgaagca
    16741 ttgaataggg aagaatcgtt tggatctggt gccaagcctc cctcgatgat ttcatactct
    16801 cctgcactat tttgtttctc aattgaaaat tctgcgcctt caagacgtcg gctattcata
    16861 ctgtcaattt tcaaaagttc caaatcgatt ggcgctagtt catcttctaa ggttacttgt
    16921 agtacaccat cgatgatttc atagccttcc ggcaagggag cagtttcgtc ttcgatgacc
    16981 gtatcttcaa tgataaactt accttcttca ttcagtgcaa actggaacac ttgatcagat
    17041 agccgatacc catttggtgc gacagattcc gagacctcat attcaccaat agacagatgc
    17101 agaggttggt cgtaatttaa atcgacatac ttttctactc ctacggcacg agaatagaag
    17161 tatccgatcc caggcaaacg tttcgattct tctggttcta acggattacc agtgtatgct
    17221 cgatacagcg ggaaggaaga atcccccact ttcctgatat cgaaacctgc accatctaat
    17281 gtatggcctt catggtctaa ttttctaact cggatctccc gataatcaaa cgtattgtaa
    17341 gcagtgaatg ctacccataa acgatcctct tcatctgttg tatacgtgag atattgccaa
    17401 ttttcttcac ctgtttgctt gagttggata gtccctatag cattatcgta aagtcgcaag
    17461 atccatgtgt cattttcatc aggttctttg aaaccttctg ggttctggct ctcaatgatt
    17521 ttgtattctg catagttggt agtttcttca ctatccttat aaacaaatga atctggctct
    17581 ccgattggat gaataacttt ctcaccatcc acgattacat atttcccgtc ttcatctact
    17641 gaatagaacg tgagtctccc tttctcttcc tctacttcgt tcacaccaga aagccctttc
    17701 gctactggat atccgatttc cagtccgtta ccatctgttt cataaagttc aaactctgcg
    17761 ccattgattg gcatattact gccttcaatt agtttattga tattcatgtg gattggcttg
    17821 aattcatttc gcatttccag tttgacatac aactcatcat actctgtgcc ttctatgtta
    17881 ggctcttgta caacagaaag cttgtgatat tctccttcat aataggaatt cggatcttta
    17941 ccttccggtc cgccgactct cgaaccagat gtatattcat ctacaagctc gtagtgacct
    18001 aacatctcat cttcgttggc tgcatatttt ttgatttgga attgatacgt ctcatctact
    18061 aactgataac gtggtggtcc agcgatctct ctgatccaaa atatgtcgct gactgctcca
    18121 gtttcatctc ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt
    18181 ttacttgttt cgattggttc ggcttcccca ctctctggat tttggtcata taatgcaaat
    18241 tcgactccag ccaacggctc gccattttga cccttcttgc tgacttggaa attacggcct
    18301 ttatgttcgt aacgaatgga agaagatggg aaatacatcc gtccagtagt gatatcattc
    18361 tcataatcct ccaggttctg aatataggcc atattgttca ctgtgcaaaa atttccgtct
    18421 tgagctcccg catcaagttt tacttggtac ttgatcctga ccatttcccc ttcacctaaa
    18481 gaaatcggag aaaatttata agcttggttt tcccgtccga catacgttgt cggagtcgcc
    18541 actacttctg gtggggcttg tccatgacgt tcttcatccc atatttctgg ctcttggtac
    18601 ttcatgccgt tttctcctgg atctagatgg taaaactgaa tatctgccga tctgccagct
    18661 ccaaatggtg agacattaaa accagtttca tcataaagtg tggcttgctg gatcgttctc
    18721 ttgaaggtag aagagatatc ctccaaggct gtaacaatgt cattcttgtt gttcgcattg
    18781 taatatcgcg gtgttacgcc atcttcttct aaatcagcaa tatttttcaa tacatttcgt
    18841 ccaatagcat ctagtcgttg tctcccgcta acgtttccat cgattcctaa accaatggag
    18901 aagatacttg gcgggttctc ttgatacttg tttttcagcc aatgatgata agcaactgtg
    18961 ttgatcgcag atgacttttc ttgcgaagta ggactgccat tcgtattgtt attagaagaa
    19021 ccatcaccaa cccagtgagt cgctttatta tctccttctt ttacctctcc ataacgatag
    19081 tgtacattta cttcatcttc tggacggtta aagtcagatg cataggtaac tggatgagta
    19141 aaccctgcat tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta
    19201 tcttcagcaa tcttatcttc catcacagtc cagttgctcc aagctccatt agtgctcgta
    19261 cgataacttg actgaatcgg tgcataactg aaggtcggtg tcccatctcc cacaacgatt
    19321 aggatttttt ctggatttct attttctccg ccattgtctt tatacaatgt ttcatagcca
    19381 tttttaagcc ctagtgtaag cggagttcct ccgattggtg tacgatttaa tgctgtattc
    19441 tcacttcccg tcaaacgatt gatatcattt gtcaatggaa agatgtccga actgatttgc
    19501 tcatggttat tgatagctgt actattatgg taaaaattca ccataccgat tcgaatatcc
    19561 agactcgggt cagagagcag atctttactc atttcgttta ctgcctcaat caacgcagca
    19621 tttttagttt gactattggt cccagcggtt aattcactca tactcgctga cttatctaga
    19681 acaaaaacga tatcgattgg actgatttcc tttttctcgc ccccgatgac atctagatag
    19741 acattgtaaa gggttgttgc atcttcagga tgtagatcag atgctgtgct gcttggcaga
    19801 acaggttcta cccatttttt gatgtacgcc ccgttataat ccaagtaact gttttcaaaa
    19861 ttccgttcat ttccccaaag ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct
    19921 gcagttgatc cattattagt agcatagtcg taatttcgcc agttcgctcc cccgtttgta
    19981 taatcactat catcgatcaa gttctctccg tcatatggcg agcctttgtc tccttgatag
    20041 cgttcattgc tttgtgtcca atttcctaac acttttgtat agtcattcgt tgtaaacttc
    20101 atctattctt tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat
    20161 cttttctgtt tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac
    20221 ataccattct tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga
    20281 ggatagacct gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat
    20341 tgctaaacgt attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc
    20401 aagggtttct tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa
    20461 tacctcatcc tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata
    20521 gactgactgg aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa
    20581 ttttaaccct ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat
    20641 caacaaaaca atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat
    20701 atccttttta gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa
    20761 attttataac gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta
    20821 cgctttcctc gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt
    20881 cgtacaatta attcagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc
    20941 tcctcctaaa atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa
    21001 acaagcaaat aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac
    21061 tgataaaaag gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt
    21121 gtaaaggaca agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat
    21181 aaaaagcaaa ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc
    21241 tctagtatca ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt
    21301 agagatatta ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt
    21361 ggcgaacttg ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct
    21421 cctttttaag aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca
    21481 agaaactgaa acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa
    21541 ggatcaacgt gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa
    21601 atgcagtaat ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga
    21661 gaagcgcgct taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc
    21721 caccccaata gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta
    21781 aactatcttg ctttccataa agagagaagt tctcacgaaa ctttttccag aatagtgaac
    21841 cgagcttttt ctcttcattt tttttgtaat gataaatcat atacagaact gttcgacttg
    21901 cagttcctaa tgtgaaaaca ggcaagacgc acaggaacca tagtagctgt aaatggataa
    21961 gacgtggaat ccattcaatg atttctaaga aataatcatt ggctttttta ccaatcgatc
    22021 gattcatcat ccttttgaac ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc
    22081 aaaaaagaac agcaaaatcg tcgggatcaa gacaagtgtt gctcctgcca tcagataatt
    22141 ccattgtgtc gttgcttggt tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc
    22201 ttgatcttgg atatataaca gaggacctaa gaaatcattc caagctgcgt tgaaggaatt
    22261 gatcgcaatg gtaatcaagg caggtttcgt caatggaagc atcaaatgac tccaaatata
    22321 caaatgattc gctccgtcga tttcagcagc ttcgatcaat tcattattga tcgataagta
    22381 aaattgacgc atcagaaata tattgaacgc attgccgaag aacgatggaa cgatcagggg
    22441 caaataagta cctacccagc cgatcttgga gaataataca tattgaggga tcatcgttac
    22501 aaaccccggg atcatcatcg tagaaagaac caaagcaaac atcagctttt tcccaggaaa
    22561 atcaagcttc gcaaatccat aagcaataaa agaatttgaa aggacattac cgatcactac
    22621 tagcacagtg atgaataatg tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt
    22681 atccagatag ttttcccata cgattttttc tgggaaaaag gtcggaggat aacgaacgat
    22741 ttcttccatt ggtttcaatg aagtaaacac catccaaagc aatggaatga tcaaaatgat
    22801 tcctattact gtcatgagga cataacttag tatttttttt gtttgccgat tcacactggt
    22861 ctttttgaaa taatccatca tttgccgtca cctccagaat aatagaccca cttaggtgca
    22921 agcttcaaat tgacaaacgt cagaaccaac acgatcagaa acaggatcat tgacatagcc
    22981 atcgcataac ccatatcaaa agctacgaac gccttgttcc acatatgcag attataaaaa
    23041 agcaaagaat ttgcaggtcc gcctgttcca tttttcgtca tgacataagc ttcttgaaaa
    23101 atttggaaag aaccgatcgt agaggtgatc acatcgtaaa aaataatagg agtgattaat
    23161 ggcaaagtaa tacttttgaa ctttccccaa acgcctgctc catcgatttc tgctgattca
    23221 tataaagatc taggaacatt ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa
    23281 ctccatattt tcatcaaaat caacgcaggt ttcgtccatt gtggatcaaa cagccaagct
    23341 ggtccaggga tatggaacca gcccagaaat gtgttgatca atcctgcaga tggagaaagc
    23401 agctgcatcc ataagatgta gactgctact cctgataaga ctgccggtaa atagaaagct
    23461 gtacggaata cactgattcc tttgattttt tgattgagta ctgtggctaa aaacacactg
    23521 aaaatcgtcg tcagcggtac attgaagatg acgaaataaa cggtgttgta taacgatttc
    23581 caaaataaat catcgtgaac gaacattctt ttgaaatttg ctagaccaat gaaattcatc
    23641 ttggatgtca aattataatc ggtgaaacta ccaataactg aaaaaagcat aggccctagc
    23701 ataaatacca agaacccgat aataaaaggc gagataaata aataggccca tcttgcttct
    23761 tttttctttc ggatagataa acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc
    23821 aaaaatggat tattgatttt gcttgactaa gttttctact gctttttgtg catctgccaa
    23881 tccttctttt ggtgattttg ttcctaaaag aatctggtca atctgttcat tcactaatgt
    23941 cgtgtaatcc ggagcatcta aaggaactgg tgtgatcacc gtatttttaa agttttcgtc
    24001 cgccatttga tagatcattt ttcctttatc cgttaggttg tcattattca ctaaattctc
    24061 attggctgtc ttgctcgcca tgatatcaaa acttttttcg ccgaattttt cttgtacttc
    24121 tggagaagaa agatatttga tgaattcata agaggcctca ggatcttttg ctccgtatgg
    24181 tacttccaag acgaatccgc caccccacga ccaatggcct gaaccttctt ctttttctgg
    24241 gagctgcatc acgccaaaat caaaatcatc cggtgcattt tccatcaaac tagagtaata
    24301 attgatattt tgggcacgca tggctactaa tccggaaata aatggatcag atacaccaga
    24361 cccaaattcg gcttctaatt tattgatcgt atttttccca taataatctt gccagtcttg
    24421 gatccactcc aaggcttcca ctttattttt agtatcaatc ttgacttttt catctttgtc
    24481 aaaccaacta gtcccgttat ctgcgtttag cgcccataca tcagccccta aattccataa
    24541 tggataaaaa ccgatgcgtg taaattcttt tccttctttt ttatctagtt tacgtgctgt
    24601 ttcttctaat tcatcccaag ttgtcggtag atcttgttca ctgattccag cttctttaaa
    24661 taacttttta ttataaaaaa tgacttgtgt atctgtattg aatgggatcg cataaggatc
    24721 accttcatat tctactgtat cccaaagctg cggataaaaa tccttagaag tgtctttttc
    24781 tacatatttg gagagattag ttgcttgctg tgcttctgct ctttgggcaa cggaatttat
    24841 gtcctgtaca ataacatcgg gtgcatttcc agctgttatt gcagataaag atttagtcca
    24901 gatgtcaccc catggctgat acttataatt tacatggatc tcgttttgtg attgattgaa
    24961 atcctcaatg atttcttcga tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa
    25021 atcaatattt tttcttccat cacttgtttt ttcagaagaa tttgctgcac ttgaactggc
    25081 atcgcttgca ttacttgatc cgcatcctcc taataaaaac aatgctgaac ttgccagcaa
    25141 ccctgtaaac aataattttt tcatatttta cctccaaatt ttaatgtaac cgatgccggt
    25201 tttaatataa cgatatcatt ttgttctgaa aataacaatt tataaggtat gattctaaaa
    25261 aaattattaa tgataccaat actttatata attcgcgagc gctttctttg aattttttaa
    25321 tctttcgtag cagaatgaga atgtattaaa aatagattag gaggaatttt gatgtttaga
    25381 caccagaaag aattgcagtt tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa
    25441 tatctgcagg agctgatcgg cggccaatat ggcgagatga gtgtagctat gcagtacctg
    25501 ttccaaggct ggagctgccg aggagaagaa aaatataaag atatgctgat ggacattgca
    25561 acagaagaaa tcggccacgt ggaaatgttg gcgacaatgg ttgctcgttt attagagggt
    25621 gcgcctgttg aagatcaaga agcagcgatg caaaaagatc caacaatcgg tgccattatc
    25681 tctggaatga atccacagca cgcgatcgta gctggcttag gacctcgtcc tgctgacagc
    25741 gtgggcaatc catggagcgg tgcctatatc attgcgagtg gcaacttgtt agcagacttt
    25801 agagctaatt taaatgccga atcacaagga agacttcaag tagcacgtat ttacgaaatg
    25861 atcgatgatc gtggcgtaaa agatatgctg tctgttctcc ttgcaagaga tagctatcat
    25921 caaaatctat gggaatgtgc agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc
    25981 ccaagtactt tcccgcgtga caaagaacga aaagacattg cttatgactt ctataacttc
    26041 tcagagggag accaaagtag tgaaggttct tgggctagtg gcaaagcact ggatggcgaa
    26101 ggcgaatatc aatggttgaa agaacctaag atcgaaggcg ctgcaccaaa attagaacca
    26161 gtaacaccaa aaatgtatgg gacacctcca ttcaagaaat aaatatctac ccgtagaaac
    26221 acccgttttt tgttccacac gctttgtgag caaaactgac taaagtcatt aatcataacc
    26281 acccttcaaa agggtggttt tctctagagc tataagctca aatcaccggc cagcgcctaa
    26341 agacgctggc tttcatattt tatgttcaag ccatattgcc tttgccagtt ttgcccacct
    26401 cttaaaaggt ttatgtacta ctccttagcc cttaaaagga tcgtcttact ctcgtacact
    26461 cagcttatct aacgcactat catgtttttc ttgttcttga atgtactttt tgatggtcgc
    26521 ttcattttgt cctacttttg tcacatagta tccttccacc caaaagtgtc gatacccaaa
    26581 tttatatttt agatttgcac aatctcttga tgatctcctg aatattggct cgatattgat
    26641 tataaattat ttttcttcta tactttggtg tgaatacaat gtggtattta cacatctact
    26701 ttgtacgggc taaactattt ccctttattg ctccacccgc atagcaagtg gttttgtatt
    26761 tcaatcgctc ggcgcgctca attaggtcta aagacaataa atctaaaaac ccgctgcttc
    26821 actgacagaa acaacgggtt ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat
    26881 ctattttatt tttttgattt tttataaatg gaaaatgctt caagaagtcc aagaaataaa
    26941 gccgtataaa aacaagaacc tatgaaatct ttatttatta gatattcaac agaaatcccg
    27001 ataacactag ccaacaatat atttatcaga agtgtaaaat aaggatgctt tttatagaat
    27061 agaactagtg ttgttttcat agactctcct ttcttcatat ttccaattaa tcacaaattc
    27121 acggcattac tagaaaaatt aaaggggcgc agaagtggaa aaatactctt cgactttccc
    27181 tacaaaccag gccatcttgt gtttaataac tataccaaat ctaaggtacc tctaaatcta
    27241 aattccattt gtggcggtga cctccaattt ttaactcttc tatctcccat ccagtataca
    27301 taaccttgat acttcgacca cttatatatc gaacacacaa atacctatcc attgcaggag
    27361 tactacctaa cttagttgct acttgcatct aaataacagc tgaaaagata ggacttactc
    27421 ttagtaaagt atctgaacta ttaattttta aactatcatt tttatcctca actacatgca
    27481 catctgttgc aacttcactt tctgtctcat ccagataaat gattaaggaa tcgggaattg
    27541 caatatcttc agctgacgct ggaatagttg agctaaatta gtcatcatat ctttattata
    27601 aaataaccaa cagcaaaaaa tacaatgaaa aacaaacttg gaactaatgt atcattaata
    27661 aatgttgaaa aattcagcaa ctcattactg tatgatttta gcagcccaac caacatatac
    27721 cctataaaag ctaataagat ggttaggaat cctttagaat ttttactcat tcatagacac
    27781 ttccttaaat aacttttatt atagaaggta ttgtaaataa taatattgac aaaaagtgac
    27841 tcaaaataaa aaaaaactta cattatactg gaatgaactg tattgatagt gtacctaaaa
    27901 gctctactga cataagatcg tgtaatcggt aaagtaattt tattaattat acgggatgta
    27961 atcaattaga gaataaacta atcataaaag gtacttttac attcataatt gtcgctttga
    28021 gattctactt tggttcacta tctgacccaa ttgcacattt tcgatcatta caagtattgg
    28081 tgtcgttaga acaactaaat aaaaactagc ggtagatttt tcagaatcta tgctaatttc
    28141 tgtatggatg ttccagtgat ggcaaatttc tcttttcatt gtttttcttg tcgcatgata
    28201 tgcctttttg tgttattcag ttaaactata gaaattcttt cctagacaga tcttgatccc
    28261 aaattttacg tttttgagca tcgatatagt ttaaaatgac attactcata tctaaagagt
    28321 ttagattttt taggactaaa actgtcagtt gttctttttc ttctttctgt taaagtattg
    28381 tcgcgacttt tcgtatacgt taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa
    28441 aacgaatgac ttgaggaaat cacctcaatc attcgtttaa aatgctatat attctttagt
    28501 ttaagatacg gaaattaatg ccatcgacca cactagtaga atgaacgaca tttacttggc
    28561 ctttttttaa tttcgttatg tttagcatat aaaaatatta tagagtttac ttacaatgct
    28621 taaaacatat actgtataat ctgatcaatt ttagccatgt cttgcaatgg taagttttct
    28681 atttttttga gttttcgttc cttaaaatca agagatttta attgtgtaat aattacttgt
    28741 ccttttatat ctagctcttc aggtaatgag taacgtgtcg gtaaattctt tatagtggaa
    28801 gtaattggac atatgaccga aaacattgtt ttacggttaa attcataacg agagacgact
    28861 agtcctggtc gtcttttttg aatttctttt cctacggagg gatcaaaatc aatccataca
    28921 atatcacctt ttttaggaat ataaattctt tcttctgaca ctataaaatt tctctccctt
    28981 caggagttaa atcttcccat tcgtctttct cataatactc ggcctcttcc ccaccactaa
    29041 atggatcttc aatttttgga actaacgtaa ttgttccatc atcagaatac acaacgatat
    29101 attcttggtt ttctgaaggt ttctttccgt tatcagaagg taaagttacc actacagaac
    29161 ttccttgtaa tctagatttt gtaacaagca ttatcatcac tcccttaata aaagtatact
    29221 atataacact aagtaacgca aaattcccct ttgtaaacta tctagaaaat tgttttgttt
    29281 aaagtatatc ttattggata taaatagaaa taaattgtag ccagttcatt ttttctttaa
    29341 ctaaaaaaat aatccaagaa acattgaacc tatggatcca aaagctaccc aaatactata
    29401 gctaaccccc cgctaccttc aattttgcag ataaaacgct ttgggagaaa atttcaaaga
    29461 caacaggcca tcctatcatg cccgattata aacaaaaagc tggctattcc ttttgctctg
    29521 acaaatttca attgggaaag ttcacgaaac tagcaggtga agaagtttca actgttcgga
    29581 tcaaagaatg cccgcttcaa atagaaacat tggttcaacg aatttcaact agacaagact
    29641 ttgctattgt agaacgtgag atcgtagcta tttttgtaga agaagggatt ttacatgatc
    29701 caactcatat caatgtggat aaatggcaac ctcttatcta taaattcaga gaatatacaa
    29761 ctgccaacca gtcgttaact ttgaatttta gattccaaga attcaaagag tcataatgat
    29821 aaacatcgtt aggtataaat aaaaaagact cgcagcacga gtaaaaaaca aatagaagct
    29881 atacattaga aaggtcgact gtgaccctat agatgcagta tatgcagctt atgagtattt
    29941 cttctgttct ctttgttttt gggatctgtg ctgaagtctt tttcgttttt tgccgctctt
    30001 tctttgaaaa atcgattatg ttataccttc tccattacta attcaggcat ctgctgagta
    30061 atgatttttc gcgcaaaaga aatatctgtt acccaaggtt cgatttgttc ttcagtcaag
    30121 acaagcggca ttcggtcatg gattggtgcg actgtgcggt taggttcagt agtcattatg
    30181 attgattctg ccattttttc atcctgatgg ctacgataaa aaccgccaat atacactatt
    30241 ttttccttat ttgaaaacat aaatttgtct ttttcttcat tccactcatt gggaaaacac
    30301 aacgattttg caaaaatggt tgatgaaagg tctttttttc ttctactgtc tctgcacggg
    30361 cattaatcat caattgtcct tttttaaatc cggtaaatcc ccacttcatg atttccggag
    30421 tgaggatgtt ttcttcctct tttcttaacg tcacaacaag atttgacgga aaaacttctc
    30481 cagctgctaa ttctgctgcc tgcttcggtt gtttcgtctg ggcttctcga taataattct
    30541 gaaggagctc tgactctaga tcaaaaaaat aacgaccaca catcctaatc cctcccaatc
    30601 tttttttcta tcatacactg caacaagaag ttcgcaccaa caaaacgctt tcaatttttg
    30661 tagaactaaa aaagttgtga caagtgacaa actctccagt gaatggtatt ctcctgccaa
    30721 ctcctcggtc acaagtcaca atattcaaca aacatgagaa gctgcttttt gaaattgttc
    30781 cttgtgactc ggagtgaaac ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc
    30841 agtttctcgg tattaagcca aatttatgca aaaatgtaga aagctatttt cacaaaattt
    30901 ttcttaatac tcgaaactaa gcgacttttt cacaacctct tccttaaacg gtgttcaaaa
    30961 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata tgagcagcta tttttatttg
    31021 gctgttctta ttacttgatg cagggcagct ttttcacaac ctctccacta aacgatgttc
    31081 aatcagctaa ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg
    31141 tttgtttctc taatactcag gtcaaagcgc tgatttcaca acctctaata cacggtgttc
    31201 cagaagtagc ttcttcgaaa aataagccga aatttcacaa aaatttgaga agcaattttc
    31261 gtaaattcct tcttatttct tgaagctgac cacttctgtc acaacctcta attattaaag
    31321 aaccttttgc gaagttaaca atctttcttt gatcaattga aaattctgcc taagtagtga
    31381 tagatcctgt gtgactttca acaataagat acttccctgg atttcagcaa tcaacgcttt
    31441 ggcttgacgg tctgcttctt catcggacag tttttcttca gaaagtgcca ggatattttg
    31501 tttcgtatac ttgacccatt gattgactaa ttctagtagc aacagacggt attcttcatc
    31561 cactgtactc aactcaataa tcaaattacc tacaggacag ccatgataag tgatctgtgt
    31621 ctcatgatca gcgaaaatcc agtccaacat ttcttctaat gcttcttctg gctgttttcc
    31681 agcatttaag atgtcttcga acaattctgt ctgccatacg tccatatgcg catggatcac
    31741 cgctagacaa acttcttttt ttgaagaaaa gtaataataa aattgacctt ttcctgtatc
    31801 agaagctgct agaatatctc ggattgacgt ttcatgatag ccttttttat aaataagatc
    31861 tttggtcgct tccaagatct tttcctttgt tttcaatgat attctccttt ttcatttctc
    31921 atagtcctat attatacagt aaattcatca ttttttcttc ttaatcgttt aaaaaagact
    31981 gtgccaaatt atctgacaca gccctcacta taaaactgtt ctcatatagc tagatgttca
    32041 ttgattcaag aactgcgagg acaaaagcaa ttcctatctt atgatagttg ctctaatact
    32101 tcctctgttg tcatcacttg atctgcaata aagccaaagt tcgtcaacgc tgcatccatt
    32161 gcttcttggc caggagcacc aattgcatct gtcgctacca caacattgaa tccactctct
    32221 accaattcac gcatatggga atcgctacac aagtttccgt tcattccacc aagaattact
    32281 gtgtcgattc cattttttct caattggagc gccaaatcat tgctttctgg tccaaagatt
    32341 ttatgaggag agctgatgat cgtattttca tccaaataag gtttcaattc ttcgataaaa
    32401 tcggctcctg aaccttcttc cactgattca tattgacttt ttctagcaaa catctgctgc
    32461 tcaagcatca tatgttctcc tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa
    32521 taatgaggag aaataaagag tttgtatcct ttttcttttg cttgttttac catttcaatc
    32581 atattttcga tcgtattgta tttttctaag atatcttttg tcaaaccaaa gccaccgcct
    32641 gctggtttca agaactcgac ttgcgggtca gtgagaacta ctgctgtatt tttattattg
    32701 aacatggtgg attctccatt cgttatttat tttaatacat catttagagc ttcactcatt
    32761 gtcggatgag aatagatttg atctctcaat aacgtataag gaagttttcc attcatagct
    32821 agcgaaatca agttgatgac ttcatgagaa tcttccgcat agatacttgc ccctagaatc
    32881 aagtcagttt cagggtcgac taaaactttg aatacacctt taggatcttc taatacttgt
    32941 gctttaggga caccgcttgt catatacttg aataatttgt aattgacgcc ttgtgctttg
    33001 gcttgttttt ctgttaaacc tacattggat aaagtcggag tgataaatac actgtaaggc
    33061 acagctttcc ggttattcgt tgttcgttta ttctcgccct tcaactgatc cataatgatt
    33121 cgataatcat ctagagagat ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc
    33181 caaatgttgt ctgcatctgt acgaaggtat tcatccacag cgattgctcc gcgatctgtt
    33241 agtttaacat ctgtattttc taatccaagt gatgctgtac ttggttttct tccagttgca
    33301 gccaaaactt ttgacgcttg gattgttact tcttggccat cttctgtaaa ggtgacggca
    33361 gctgttgatt cttggtctgc tacttgatct acagatacac ctagatggaa ttcgattccc
    33421 gcatttgtca tgtcttctaa aatcatttgc gcgatatctt catcttcacg tggaagaaat
    33481 tcagaatggg catcaagaac gacaacttta gatccgtatt cattgaacat tgatgcaaat
    33541 tccaagccaa tatatccagc cccgatgatc actaattttt ccggtaattg ttcctgatcc
    33601 atcgcttgcg tagaatcaat caagtagcga cttgtattca atcctttgat tggtaaaatg
    33661 attggttcag aaccagtatt gatgaaaatc cgttcgcctt caacaatcac tttttcacca
    33721 ttattcgtca cttcgatttg atggttagaa agaaaacgtg ctgtaccgtc catcactgtc
    33781 ccagttgcct catcgctgat catatgataa tttttggcgc gaagcatgcc cgtcaatttt
    33841 tctttccgag caacagcctc tgtaaagtcg attcctcttt ctccattgaa aatcaatgat
    33901 ttagaaggaa tacagccgat gttgatacat gttccgccat acatacgtgt tgacttttca
    33961 acgactaaaa ccgattcacc ttttgaagct aacgccttcg ctaaagtctt accgcccttt
    34021 ccaaaaccga tcacaatatt ttgatatttt tccatcattt ttccctcgct tcttttttac
    34081 ctaccgattg gtacaaaaat atgataaccg ataattgtct attctccaaa tcatctgctt
    34141 tatttgtcaa aaaaaaccag acaaaaagcg gtcctttcac gtttttagtc tggttcgatt
    34201 tcctttattc ttctaaacaa tcgttacttc tacatcgata tttcctctag ttgctttgga
    34261 gtaagggcag aattcatgcg catcttctgc aattttttgg gcttcttctt cgctgatgcc
    34321 atcgatatgc acttctaata ctacaccgat ctgatagccg ccatcatcta aattataaag
    34381 agagacacgt gcttttactg tggactctgc tgtcattcct gcttctttga tcatatgttg
    34441 taccgcccca ttgaaacaag aagcataacc tgctgcaaat aattgttctg gatttgttcc
    34501 ttctgcatgg attcctggag gagtgatttt catatgcatc gagccatttg gtgcctcgac
    34561 ttctccattg cgcccgccat ggttgatcat tgctgtttcg tatgcttttt tcattgtact
    34621 gctcctttcg attgaccatt tgctacttgg ctataattat agtgtatgac aagtaaggcg
    34681 ctttctacaa aaattctgct tattcgaata ccagaatgcc gtcttctact atttttccaa
    34741 aaaacaaaaa aatactactc gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa
    34801 tcttttctac ataatctttt atatgattga ttttaagata catatatacc agaaagttga
    34861 ccccataaac caatactgtt aaaaaaataa ccatattcgt taccattttt tcctcctttt
    34921 gctggtctcc ctaccagcac tcgatttaac cataccactt tttttgccgt ccaagcaact
    34981 agcctttcaa aaagactggt ttattctgct gttaatgatt caagatcaga aaaatgtccg
    35041 aataattttg ctaattttac taacgccaac ttgttctttc cgaattcatc attttctatc
    35101 tgtaatacta gtaacggctc atgtaagctt aaacggatca aaaaccagcc gtttccgtat
    35161 ggctcttcta gatcatatcg aataccttct tcattttccg ggtcgaagtt catccctttt
    35221 tcttcttcca acagtcgctt catttcttct aatatcttgt ttccttgttc gcgtggttca
    35281 tcgctgaaca attttaatcg gatttcttgt acttctacgg gctgtttcaa ctctttgatt
    35341 tgttcatcta atgtgatacc ttttcttttt aattctggca aaagcatcag gatctttgcg
    35401 atgacatatg caccatcatc cagaaaatag ttttccttga atgcagcgtg tccgcttgtt
    35461 tcgatggcta gctgtgtatc tttcccaaga cggttaagtt ctaatgcttt attgattaca
    35521 tttcgatagc cggaaatata acgaacttgg atgcctcctt tttcttcaat gaatctttgt
    35581 agatgagaag aagtagggga attcgtcacg attcttgttc ctggatgctc ttttaatacg
    35641 attgtactta atactgcgat caaattattt cgattgatca ctgttccaga agcactgaca
    35701 actgcagaac gatccacatc tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa
    35761 acagcctgct tgatactttc catcgcttct ttattatcag gatttgggat atgattagga
    35821 aatcggccat ctggttccaa aaattgggaa cctgttgaat ccgcacctaa gctattcaat
    35881 actttttcag caaagaatcc accagcacca tttccggcat caacaatgat tttccaacca
    35941 tttagtggtt tgctttctag tgttccaatc ccctttttaa tttttgtgac taaatcttgc
    36001 gcataaggtg tcaaaaggtc tgctttttct acgcttccag tttgttcgct ttttattttt
    36061 tgctgctgtg ataggataaa agcaatatct tctttttctg ctcctccttc tgaggtaaag
    36121 aattttattc cattataata atagggaaga tggctagcag tcagcataac cgcagcatcg
    36181 cacgagaact gttcaaattg agtggacata aacatagcag gcgtagtagc taattcgaaa
    36241 tcgatgacat gtatcccttg ttctttcaga ctttggatca acgcctcttt cagtgctggt
    36301 ccgcttatcc tactgtcatg accaatccca atcgtccatt ttttatttgg atcggttgat
    36361 ttcttctttt tctttatcca gtttgctagt ccccagccga tcttttttac catgtctgtc
    36421 gtcaagttta cttcatatcc ttcaactggt aatgcgattc ctcgaatatc cgatccattt
    36481 tgcagcgctt tcatatcttt catataaaag tcctcctcat ttattccctc attttttcca
    36541 gcttttctgc aaatcgctgt gcttcttctt ctgagcggca aataataatg aatgtatcta
    36601 caccggccat cgttccgaca acttcagggt aagccacttc atctagccaa ttcgttacca
    36661 catcggcacc atttcgttca gtcaatacga taaccatgaa ctgaacagac tggatacgca
    36721 aaacctcgcg tctaattgct gtacgcaaac gttcttcatt taaagaaaca gatggctggt
    36781 taaataatgt atagcgtact attttgtttt cattttgact ttttactaac ttcatttctc
    36841 gaatgtctcg agaaatcgtt gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa
    36901 gcagctcttc ctgtgtccca ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc
    36961 gctgtttctt tttcatatta gacacctctc aatgttgatt atagcaaaag ataagtaata
    37021 tttcttcata ttttggtatt ttttactttt attttttgtt ttcattcagg ttgctaacct
    37081 ttttctattt taacacgcaa aatcgtcttc attttttcag gtgctgattt tcttggatcg
    37141 ctgatgtaaa tctctttgtg ttctttagaa gctctttcat agccttcttt tgcgatgaat
    37201 gcttctaatt tctcaaacgt tgctggttct tcggcatagg gcccgacgtg taagatttgg
    37261 gcacaaagac cttcttccat ctttttgaat actacttgtt ctttcaagtc ttccggaagt
    37321 ttgctagaac gctgaatggc ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg
    37381 atcatcaatt gataagaaaa atgttctttt ttcatcactg gttcatgcaa atacttttct
    37441 tgcagtcccc attgtccttc cagtggatag acagtataca tctgataatc aggaatcagc
    37501 caattttttt taggcgacat gcgtattgca tagctgactg catatagaca ggctactctt
    37561 cgtttaaagt cttcctgatt cgggtcgccg atccctctga tgctaaagaa tgatttttta
    37621 ggaacctcta gtatttgcgg gctttttttc atactatagc tcttgtcttt acgccattca
    37681 attttttcca tttttcttcc tccgcgaaat tccatttagt tatttattat catacctctt
    37741 tttgagtgac ttggctaatc gtgttgacac tatttttcag tttgtgctag aataagtgaa
    37801 gtaaataaat cgtacagata acacgtttcg gcgtgtcgag agagaggcgg tttctatttt
    37861 tataatagaa atcactctct ttttttacga aattttttag aggtgatgta aatgacaaaa
    37921 caaaaacagc tgcttttagt acctgcagta attgcaacag ggatgatgtc ttttgcgggc
    37981 gtattgatcg agacggccat gaatgtaact ttcccaactc ttatcagaca gtttgattta
    38041 acgactgcac aagtccaatg ggtaacaacg atttatcttt tgatgatttc gatcattgtt
    38101 ccgctgtcta cttatttgaa tcgcaatttt agtctcaaaa aactcttttt agcttcaaat
    38161 ctgcttttct tggcaggtat aatgatcgat ttcttctctc ctaccttcat ggtcctattg
    38221 tttggtcgat tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat gttccatatt
    38281 atcttgacat ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg tactttgaca
    38341 acggccattg ctccagcaat tggccccact tatggaggca ttatgacttc acattttaca
    38401 tggaatcata tcttcctgtt tcttgtgccc gttttgattc tttctttgat tatcggctgg
    38461 tttgctattc ccgagatggc agtacaaaaa agtggttatt tggattggat aagcgtttta
    38521 ggaatttgtc ttttgtttag tggaagtcta acatttttga gtacgttggg aacagtttcc
    38581 agctggattg ctttaatcat cggcggtatt ggctggttcc ttttttacta tcgaagtaaa
    38641 aaagtggagc atccactgat ccgactgtct attctttcaa ataaaacatt ccgcttgttt
    38701 ttgattggct tcttagttta tcagttttta ttacttggtg tatcttttgt cttgccgaat
    38761 ttccttcaga tcgttcaagg aagtagtcct tttgtcgctg gattagcgat gcttcccggc
    38821 gcagcggttg gtgctttgct ttctcctttt tccgggaaaa tgctggatca atatggtccg
    38881 aagaagccaa tttttgctgg gctgattctt tctttgattg gttggctagc attattccta
    38941 ctcataggac acgcttcagt gggtgtattg attgcttgtc atgtgtttta tatgatcggt
    39001 atcggattat cttacagcaa tatgatgacc accggaatga atgcactgaa tgaagaacta
    39061 caaggagacg ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc tgtggctact
    39121 tcattagtag cggtcattat caattacgtc cagcatcata cttcccataa ctatgaagtg
    39181 tctactacat taggatcaaa agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc
    39241 tttgctcgat tcgcctatta tctgttcttt gctaaaaaag cgtagattcc atatacggca
    39301 ggtgttgcat ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta
    39361 tggaaaaaat tgccattatc ggtggcggga tcattggtat gaccctagcc agttacttag
    39421 atacatcaaa attcaatgtt gctttatttg atgaagggac aggacaggca actaaagcta
    39481 gcgctgggat tatctcccct tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg
    39541 ctaaagacgg cgctgctttt ttccctaaac ttataaaaga tttccaactt gatcaaacga
    39601 tttacgcaca atcagggaca cttttgcttc gacctgaaaa agatttagct gaattggctg
    39661 ttcttgccga gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa tggctttcac
    39721 ctgaacagac atctcaagca cttccgttat tgaaaccagc agtttcactg cgtatcagtg
    39781 gtggtggtcg tctggatgga aaagcatatt tagaacatct tggtcagcgt ttagcacaaa
    39841 aacaaatgga gcagatccag gcaaaagtca ctttgcataa gaagagcgat tcttggctca
    39901 tcaagggacc gtttggagaa tacacagctg atcgtgtaat tttgacacct ggcccggcac
    39961 ttaagccttt attacaagaa ttaggctatg ctgcagatat acgtccgcaa aaagggcagc
    40021 tcttagcatt tcagacatct tataagatga gtcaagactg gcctgttgct atgcttgacg
    40081 gagaagctga tttcattcct ttcatggatg gaaagatcct tttaggtgct acccatgaaa
    40141 acgatcaagg ctgggatttg gctcctacta gcgaagctta taagggattg actaagagta
    40201 cagaacagtt cttgactgat ccagatcaga taaaaaactg gccatacgag ttccgtgtag
    40261 gtacccgtgc ttatacgtca gatttttccc catttttcgg cgtactgcca gatgatccaa
    40321 gcttactggc tgctagcggt ctaggctctt ctggcttgac cacaggtcct tatatcggct
    40381 atctattagc caacttctta aatactggtc attggcctac ggaagattat caaaaggaca
    40441 tctccaccta tattacgaaa aatccatcat agaaaaacag ctttttcaag taaggatccc
    40501 gagcgatatt gcgcatggat tacttcttga aaaagctgtt attttagttc aatttctgaa
    40561 tcaaattctc caaactttct tttgcttcat ctggcaagag atcttttcct atctgagctt
    40621 caatgaatcg taaacgaata tcaagtcgtt gtttcaccag atttttatag gacgtatcct
    40681 caaaagaaac aggaaaatct ggtataggta aatagtggat gtcttcaaat ggaccaaacg
    40741 acttgaattc tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt
    40801 tgattttttt atcatcgaaa tatccagtat tcaggacata gcaggctgtt tgctgtttca
    40861 aaaacaactc tcgaaaagct tgatagtctt ccctaagagg atagacacgg aaaggattag
    40921 caaatggttc aatgactagc tcatctagct gtctttttgt agtgatattt tccgcgtctg
    40981 atcgttttgt tgctaatgtt gcaccaaaag acgctgctaa aactgggtca ttgatcttga
    41041 taattggcgg aagcgaatca tctttcatga tccaaaaaac agcatcgatc ttttcgctaa
    41101 gatgatcgac tcggtcgggt gtcgcataac gtgatttgac tgtccgccca tttccgtttc
    41161 gtatatctcc tgttactagg actttttctc ctttacttgt acatgtcacg cccacattct
    41221 gacaagtaag gaaagaagaa atggccggat catcagacgg atagtcttgt gttttatcaa
    41281 agtaagaagg ttccaaggca gtagcaaaac cattttttcg agaaataacg aaagcatcgt
    41341 catgcaagat cgaaacagag tgaccttccg tatgttttgc taaggtaatc gttgattttc
    41401 cagaaccgga caacccaaat acagccatcg tataggtctg gtcattacta gcatattgtt
    41461 tcatcccacc gtggcaggca ataaagccat tgcgatttcc caatgcccaa gcaagcgtca
    41521 aagtcgcttt ttttaattct ccaaagtaac gtaatcctag cacaaccgct gtattatgga
    41581 gagcatcaaa caaaatgagt ccatttggaa atgtttcatg tgtccattcg ggatcacaaa
    41641 agatataaag atctccctca tcaaaggaaa cagacttttg ataagtctct aagatcttcg
    41701 aattcgctgg ctgaaaattc agcaaataag aatacaaatt gttctcaaat ccttctggaa
    41761 tcagcaaatg actttgcaca gaaaattctt cagataggcc aacgattact tttgtatggt
    41821 aaaactggcg cttgcgactt tgatacacag cttctcttaa aattttctcg tatttgcttt
    41881 gttccttgtc taagtcctca aagatccgcc gagcacttgc tgttcttccc acaatgcttc
    41941 catcattgaa tactagtgtc ctaacatcag ctggtaaatc tagttcttca gcatgtgaga
    42001 ttgttaaatc tgtgatgatc gttcctggac tcccttttgc tagttgataa gctgtcttcc
    42061 tatcaaaaac ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac
    42121 tggataacag tggatttcca cttgtgattt cgtttaattc gagactctct tttgtactca
    42181 tggctcctcc tcattcccta aacaaaaaaa cgttttcttt attatacatt attcgagttt
    42241 ttatttgtac tgctgcgctg tgggaagcaa acgagttatt tttcacacaa aaaaaccgag
    42301 aacttgaata aacaagtttc tcggtttcat cattttcctt ttatcggctt agtaccagcc
    42361 gtttgctaac cagaatgttt tagcagcatc ccatgaacca taacgagatg ttacatattg
    42421 ttctgctaca cgttcttgat tggcagctga atagtcgccg tttaagtatg aagcatctaa
    42481 ttgataacgg ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg attctttttg
    42541 tgcgatccat tcttttgcag agcttgaagt tggcgctgtt gcagcagctg gggcagcagg
    42601 agctacttca actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt
    42661 tgtagatgct gtattttctg ttgttttgtt ttctgttgtt gctgaagaat catttgaagt
    42721 tgggattgtt aattgttcac caacataaat gcggttgatg tttgcgatcg aatttttttc
    42781 agcaattgca tcgatcattg agttgtctcc tgcaaatttt tgtgagatct tagataatga
    42841 atcacctgat tttactgtat aaacttcatc agcgtgagca tttgtagttc ctacaaacat
    42901 tgcagtagca ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg aattcatatt
    42961 aaactccttt ttttctccgt tttttattct ttcgacgcta ttaactttat catttagaaa
    43021 tatttcatag gtaaaagaaa catgacattt aatgacaaaa taacgaatta tttaatattt
    43081 gtaacattta aacaaatatt tttttgatac aaaaccataa aagccttgtt gtataagcaa
    43141 agtaatcgtt tttctatgtt tttttatttt tgaatgaaaa acgcagattc tgtaacattc
    43201 actgcaataa tccataaaaa aaagcaaaaa aatttttgat ttttatcaaa ttctcttaaa
    43261 aaaatgtaaa aaatacaaaa aaaccagtaa ttgttacaac aattactgga caaaaacttt
    43321 gaataatgtt aactattttt ttattttaac tttctccgca ataatttctg ggcatgttcc
    43381 aattcgttta taacgacttc ttctgtttct ttagctaata tttcatctaa tacatcaagc
    43441 catttttccg gttcttttgt tcctagacgt ccaatagccc aagctgctgt tcctctgatg
    43501 acagggcgga catctgttaa acattctgaa atctcaggca atgccgttcg atcacctaga
    43561 ttagctaaag caatcaatgc gtttctctgc aaaggtttct tcccacgcca tgaaccagct
    43621 aaatgcccaa attgctgttt gaagtcttta ttagacatcg aaagcattgg ctttaatttt
    43681 ggatatattt cgtctacttt tggttccatc tcttcatgaa aatgaaaatc ttttccttga
    43741 ttgtaagggc agactaactg gcagatatca catccataaa tgacatttcg cattttttta
    43801 cgatattctt ccggcatcat cccttttgtc tgagtttgat aagacaaaca tcgctgggca
    43861 ttcattcttc cgtcaccaag caatgctttt gtcggacaag cagtcacgca gcgcatacag
    43921 tcaccgcaac caaattctcc tggtttatca ggctcaaata caatattagt aacgatctca
    43981 ccaagataga caaatgaacc gaactcttca gtgatcaaca atccgtttcg tccaataaat
    44041 cctaaaccag ctcgctgtgc tacagcgaca tcgatcagtt ctccagtatc tacttgcgga
    44101 gctagacgcc attcctcttc tttttgccat ttttctgctc ttgtttggat gaattcgatc
    44161 aatcggttca aacggtctct gagtatatca tggtaatcga tcccccaaga agcacgagca
    44221 aactgcccgc gtttttcatc cctaggcact tcttcatgga tcctagtagg atacgcaagt
    44281 gcaatggaaa tgatcgattt cggctgatca aatgtcattt ctggataaag acgctcatcg
    44341 atatttggat gttcaaagcc agaagtatgg ccagctgctt tttgttcttc caacgattct
    44401 tttaatgaat caaaaggttc cgccgtggtg aacccgattt tgtcaattcc taatcgtttg
    44461 ctttcttgta tgatttcttc ttttaatgtc atggtcttcc tcgcttgctg ttaacggctg
    44521 tataacccat aatatagttt ttcttttttc agctggacaa actggatctg ctgatcggca
    44581 atcttctttt cttccatcca tttttttctt gcagcaaata cttcccaata atttgttgaa
    44641 attaattttc ttttgttatc taatgcatta aaaaaattca atgaaactgg ttttgtactt
    44701 aacagttcat ggagccttac ctcttcccat ggcgaaaact cagacagatc gcgggaatac
    44761 aatacttctt catagagatt tttttgctgt gtgtacgtga atgtttgcgg gattttccca
    44821 ggcctagcaa tttctactag acgattataa aacatattca ttaatttgct gttggcaata
    44881 aattgacttt tataataggc cgactggatc tttttgatta ctccttctgc tttgatgact
    44941 gaaaataatg caggccatgc tttgacggtt atttcgtcgt tttgtttaac taatacgcca
    45001 ggtgtgaagc cgactggaga aaggaacaca aaataaccga taccggtatt ttcatctaaa
    45061 ggctgaaatt catcaaacaa ccatttgcct atgtacagct cttcatctgg ttctgttgtc
    45121 tcattttgat ttgctatgaa taatttagct aattctgctt caagaaattg aaggtcttga
    45181 tccttgtcgg tattttcctg ctggctgatc aatcgaaaga cttcttcttt aatcgtatat
    45241 ttatctttac gtgtaaaatt catagccaca ccttccttcc ttactctaac tataacggaa
    45301 tttcttcaaa aaaggtatct gtacgacgaa aaacagcata attttttttc atatctctta
    45361 taaaaaatgc aaggtctgct cctcaagcta gaccttgcac ttttcagctt tcttttgttt
    45421 gtgacaaacc ttcatggatc gtttcaatat tccatttcat catctgatag taagaatctc
    45481 cttgttctcc ttcttttgct atggaatcag tgaacagttt atcatagatt ttcaaacccg
    45541 tttcttttgc tacccgttcc atgcttcttg agtctacact ggtttccacg aataaaaccg
    45601 gtacttcttt tgctcttatc tgatcaatga tcgctttcat ttgatcaggc gtaccttgac
    45661 tttctgtatt gatctcccat atataagctg ctggcaaatc atatgctcgt gaaaaatact
    45721 tgaatgcccc ttcacttgtt actaataatt ttttgttctc ttcgatagaa gcaaaacttt
    45781 ccttcgcttg tgtatctaat tcttttagtt tttccacata tgcttctgca ttttttttat
    45841 agagtgtcgc attttctgca tctttttcag agaatatacg tgcgatttcc tccacatatt
    45901 ttattccgtt agataggtct agccaagcat ggggatctgc ttttgtatgt tcttcaccgc
    45961 tagttaaata aagaggttct acatttttgc taactgcaaa ataatctttt ccttcttctt
    46021 ttttagccgt ttccatcaag ttatcgaacc agctgttacc tgtttcaaga ttcaaaccgt
    46081 tgtataaaat aacatctgca tcgcttgcct ttttgatgtc ttctggtagt acttcatatt
    46141 catgcggatc tgttccgact ggtacgatac tgtggatatc tatttgatct gttccgacct
    46201 cttttgccat gtccgccaag atcgaattgg tagccacgac tgacaacttt tctttacttc
    46261 cttcatccgc ttggtcagaa gcctgctttc cgcaaccggc taataccaag aaactaactg
    46321 ccaagattaa aaagagtgat ttttttgttt tcatctatct gcttcctttc tgaaataaaa
    46381 ttccttttgt tggagaaaat aaaaaagcaa ggataaaaaa tgcggtacat gctaacacga
    46441 tcgtagctcc tgatggccaa ttgtaactat aactgaaaaa cacaccgaca actgcactta
    46501 gcataccgat tcctgcagct gtaatgatca ttttcagtaa atggttcgtt agcaagtaag
    46561 ccgtggcggc tggtgtgatc aacatggcaa tcaccaagat tgttcctact gtctgtaaac
    46621 tgactacagc cactaatgtc aaaaagaaca tcaaaagata atggatcagc gatgtgttca
    46681 gcccataagc ttttgccatt gtcggatcga atgatgtgat cttcaattct ttataaaaga
    46741 aaaagacaaa tatcaagacg attccactaa cgagtgctgt cagcaacaaa tcgctttccc
    46801 taacagctaa gacattccca aataaaatat gatacaaatc tgtcgcactc tgggcatatg
    46861 aaatcaagat aatccctaat gcaaaaaagg agctaaagac aattccaatc gctgtatcat
    46921 ttttcaatcg gctccgctga gtcacgaaac caatcactgc tgctgttagc atcccaaaag
    46981 cagtggctcc aaagatgtaa ctaaaaccaa acatataaga aatggctaca cctggaagaa
    47041 ctgcgtgaga gatagcgtct cccatcaaag acatccctcg taaaataata aaagaaccga
    47101 tgactccaga agcaagtcct acaagcatgg aagtgaccaa agcgtattgc aggaattgat
    47161 aattcattaa tccatcaata aaggattgga tcattttttc tctcctcctt ttactaaatg
    47221 tctgatgatc tcaccatagg ccaattgaag gttcttcgat gtaaagactt cttgtactgg
    47281 accggaagcg atcagctgtt tatttaaaag aataacctca tcgaaatatt cttctacttt
    47341 atgaagatca tgatggacga tcaaaatcgt ttttcctgaa ttcttcaatt cctgcaagat
    47401 gtcaaagatc tttcgttcac ttaacgcatc aatccctacg aatggttcat ctaaaaagat
    47461 ccattctgct ccttgggcta gagctcttgc aataaaaact ctctgaagct gtccacccga
    47521 tagttcgctg atctgtcttt tggcatattc ttccatccct acttttttca aagcttgtct
    47581 tgcacgttct ttttcttttt tcccaggtct ttgtccaatt cgtaaagatg gatatgttcc
    47641 taaaagtaca acgcctaata catcaattgg aaaggaaaga tccaattcac ttcgctgttc
    47701 cacgtaggct atttttttac ggactgagtt taccgactgt ccagaaaagg tgactttacc
    47761 agtagtagct ggtatcaact ctagcaaaga tttcataaat gttgattttc ctgcaccgtt
    47821 tggtccgata ataccggtaa ttttttgtgg atttatcgtc aagttgatag ttttcaaaac
    47881 agttttccct tgataagcgg ctgaaaggtc ttgaattaca atggccgtac gttccaaatc
    47941 ttacactcct ttttaggttt acctaacttt ttatttaaat atagtttaac taaaatggaa
    48001 agcattttca agtagaatga tgaaaaagtt tttttcgaat tttcctcgca ttttatgaaa
    48061 attttctgta gaatcacatc aagagttcaa taaggctaac ctaataatga aaaacatgtg
    48121 ttgaaacgtt tgattatttt ttcttgttga ctcaacaacg aaaggagttt ttgtatggaa
    48181 gaagaaaagt taactcgaag tcttagtgcc cgtcatatcc aaatgatcgc actaggtgga
    48241 acgatcggtg tcggtctgtt tatgggtgcc tcctcaacca tacgttggac agggccctca
    48301 gtgatgggag cctatgcgat tgcaggattc tttttgtatt tgattatgcg tgctttaggc
    48361 gaaatgcttt acgttgatcc ttcgactggt tcttttgcaa attacgcgag cgagtacatc
    48421 catcctgtgg ctggctactt gaccgcttgg agtaatattt ttcaatatat tgtcgtagga
    48481 ataagtgaag tgattgctgt aggatcttat atgaattatt ggtggcctga tttgccggca
    48541 attattcccg gaatcattgt cgtcttgttt cttatgctgg caaatcttat ttctgtcaag
    48601 gcgtttggcg aattagaatt ttggttttcg atcatcaaag tcataacgat cattttgatg
    48661 atcattgcag gtcttggggt aatcttattt ggatttggta atcatggtca ggcagtaggg
    48721 atttcaaatc tttggaaaaa tggtggattc ttcactggag gcgtcaaagg atttttcttt
    48781 gcattatcga tcgttgttgc ttcctatcaa ggaatcgaac tgatcggaat gactgctggt
    48841 gaagcagaga atcctaaaaa gacgatcatt gaagctgtcc agtccactat cggtcgaatc
    48901 ttgatttttt atattggtgc tatttttatc attgtgagta tctatccgtg gaatcaattg
    48961 agtgagattg gttcaccttt tgtacaaact ttttctaaag tcggcattac atttgctgca
    49021 ggactgatta attttgtcgt gattacagcg gcattatcag gttgcaattc agggattttc
    49081 agcgcaagtc gtatggtcta tacacttgcc ataaatggaa agatgtctaa aaaatttctg
    49141 aaactatctc gtcacggtgc gcctttttat cctgtcgtag caatctcagg tggaatctta
    49201 attggtctga tcttaaatta tcttctacca atgttcatca accagtcaga aaatattttc
    49261 gttttcgtat acagctcaag tattttgcct ggtatggttc cttgggtagt gattttgatc
    49321 agcgagattc gcttcaaaaa gaagcacgca gataaaatgc atgatcatcc ttttaaaatg
    49381 ccactatctc cttatacgaa ttatgtgaca cttgcttttt tagctatcgt attgattttc
    49441 atgtttatca atcctgaaac gagaatctca ttgattattg gactcgtttt cttgctttac
    49501 atgacgatcc attactttgt acgcgaaaaa agaaccggaa aataaaaaaa gaacgaagct
    49561 tcaccttagt ggaagcttcg ttctttttta ttgcttttat caattcaatt ttagcgtctc
    49621 accgggagtc aggaaataat tctccatgct catcccattc agcgacaaga tcgtttctac
    49681 tggtacgcca gttcgttcgg ctatttgatt tggaccttct ccttccaaaa ctacggttgt
    49741 cgcagcctgt gaagtcgcgc tgttggtatt agtttcagag gaatctgttg tgtcttgtgt
    49801 tgttcgagct tgcatttcag aagcttctac cgactctgct gtctcagaat cagaagatgt
    49861 tgtgtcttgt gtgcttgttg actctgcttg aagagaggcg ctagtctgca aataaatatc
    49921 ggaaatctta gcgacatgat tcgtataatt agccgataat tgattgatca aagtatctaa
    49981 gtctacaccg tctttatttt ctgctgcctg atacgctgca cgtaattttc tgatcccttc
    50041 gtcggagatt gcttgaagct cacgtgcttt ttggttagca actgctgata aaccagctat
    50101 tccctcttga tttccctgaa tttctgtctg gtattcttca atcaatgcag gcgtcttttc
    50161 ttcgatcttt ttcgaataat catttacgat tgcttgaagt tgctctggca aaccatttgc
    50221 tgttttttct tcagaagttt gtgtctcttt tgttttagtt gatgactcac ttgtttgttt
    50281 cgtctctgtt ttctttgtcg ttgtttccgt tatggtcgta cttttcgctt ctgacgaatt
    50341 ttttccatga aaatatagac ccgcaactcc tcctgctatg atcaaaaaca cggcaactgc
    50401 tgccccaatc atgatcatcc gcttacgagc tgcttgtttt tgctgtcttc ttcgggtcat
    50461 ccgaacattt tctccccact cattttcatc atacattttt ttcaccacca atttttatgt
    50521 ataatagcgt tatcaaacgc ttcatattct tattgtagca aataattgtc gctgtgcaca
    50581 tttttatctt tgttatttat aagaaaattt caccagttga gatgattcca agattgtccg
    50641 tcgatttctc cttgcagctg cattgttcgt tcgtctatct cagccatcag tttctttatt
    50701 tcatataaga gcgcacggtc ttgatattct gatttttcgc ttaattcatc taattgttgg
    50761 atcagccaat catttgtcat aatgaagttc ctttcatttc ttgcagtgta aaggtcaagt
    50821 cttcgatctg ctcttttgcc tcagtcagtg cttctacgat atatgcttgt ttttcagatt
    50881 cttcttcctg cattttctga ttttcctgta ctctttgaat aaaccagtca atccgctgag
    50941 tcagcgatgg tttgccttcc aatgagagat actgctgata agcaattagc ttctcccaac
    51001 gtttttcctg ggataaatac ataaattgtg ctaaaacgaa tggcggaaga taggtcatat
    51061 ggaatttatt tgcgattcgc tgatacggcc tcaaaaattc ggaaatcgta tattcttctt
    51121 ttcctccagc ttggtattct ttttccgcca cacctgttgt caatacgatt cctagttctt
    51181 tcccttttaa tacatgtgct gctcgttcca agacattatc ttgccaaatt tttaaatgag
    51241 caggagaact ataccagtaa aacggaaact ggaaaatgat ccgatcatgc tgggccaaga
    51301 gctgtagttc agtctctata tctatttttc cgtctggata acttgattcc aaatgatgcc
    51361 aagtagctgg taaaccagca gaagcttctt tgaaaaattg ctgatttaaa gattcttcga
    51421 tcgttggatg gctaatgatg ataagtgtac gcatcccttt tcctcctttt tagtcttcgc
    51481 tttacagtgt agcataaccg ccacaagttt cttttgccga tgcttgtcat tttaaccaga
    51541 ctaatcaggt tgtccaagaa actgcggttt gtttttccaa ctgttttttc aaggtatcca
    51601 aagcaatatt cttaaaattt tcgtttttca tacgtttacg atagttcgta gccgtttctc
    51661 cggtactctt tttgaacatt cggctaaata cgactagact attgaaccct acttgatagg
    51721 caatactttc cacggattca tccgtcagag aaagaagaaa cgcccctcga ttgatccgta
    51781 ccccgatcaa atattccttg atactggtac ccatatgatt tttgaatact cgcgacaaat
    51841 ggctccgatt gaccgctaaa tgctgggcga tttcctcaac agacaatttt tcagcataat
    51901 gtgcctcgat gtatttgact gtttcaacag ctaaagagga atgaaccttt tgtacaccac
    51961 cgctgacctt tccgccatct tttaaaagga ctgataaaaa acggtaggtt aatgctgtta
    52021 actgtaattc attttccaag gtttcttccg tatctttcat gcattctaaa ataatgtcga
    52081 tatatttttg tatgtcagaa gagaccatcg tgtattggtc ttctctgaaa agcgactgcc
    52141 gaatgatttc ttctgcagca ctcccaccaa atgaaagcca gcaatacatc cacggatctt
    52201 ctccatctga taagtaaaac gtcgagtctc ctggacgaat caagaacaga tcaccttttt
    52261 tcaattggaa ttgttgattt ttcacatgat aagatccttt gccttccatc acgacatgca
    52321 ggatgtaatc attgcgaata gcaggaccaa aagaatgaaa cggcatcgtt ttagagaaac
    52381 cacaaaaatc aaaatacaat tctttttcta cttgttgatg ttcctttttt aaaaaaatcg
    52441 attgctccac gtctatccct ccttactcct ttagtataat gcaacaaaaa gttaaataaa
    52501 agtcacagaa atatattaaa aaggaagcga tttcttgtta agtttaagtc attaaaagat
    52561 ctttgttatt cgttgtaacc ggtttactta gtattatata ttgaacagga gaggaataca
    52621 gattatgaaa agcaaaatga tccaacgtgt gtcctacgct ttaggcgctt ttggacacga
    52681 cacattctat gttacattaa gcacttattt tatggtattc gtgacaagcc agatgttcgc
    52741 aggaacagat aaggcaacga atgcaaaaat gattgctaca gttacaagct tagttgtagg
    52801 tatccgctta gttgaaatta tttttgatcc tttgattggt ggcatcatcg ataatactcg
    52861 tacaaaatac ggtaaattca aaccatggtt agttatcggc ggcgttgtta gttccgtact
    52921 cttggtagca atctttacca atttctttgg cttagctact cataatacga ctttatttat
    52981 catattattt gcaatcgttt tcatcttatt ggatagtttt tattcattta aggatatcgc
    53041 tttttggtca atgattccag ctttgagtac ggaaacaaag gaacgtgaaa aatttgctac
    53101 gtttgctcgt ttcggctctt ctctaggtgc aaatggtact actctagtcg ttgtccctat
    53161 cgttactttc tttacctatc ttgttactca taaacatatt gaaggcgctt caggctggtt
    53221 ctggttcggt gtgattgctg ctgttatttc aggcggtact gcgattatca ctgccttggg
    53281 cacaaaagaa gtcgatactg cgatccgtca gcaaaatgaa aaagctggga tcaaagatgt
    53341 gttcaaagca gttgctcaaa atgatcagtt gatgtggctt gcccttgctt atatcgctta
    53401 tgcgattgcc aatgtagcaa caactgccgt attattctac ttcttcaaat atgtacttgg
    53461 ccaaccaact gaattttgga tcgttggtct agttgctgcc ttacttggtt tagtagctgt
    53521 tccactattc ccaatgctta cacgcgtcat ctctcgtcgc tacgtttacc ttggagggat
    53581 cgcaatgatg atttcttctt actttttctt tacgatcgca ggttcaagtt tgccaatcgt
    53641 tatcatcggg ctagtattgt tctacttccc tcaacaattg attttcttat ccgctttgat
    53701 gacgatcaca gactctgttg aatatggtca atggaaaaat ggtatccgta acgaagctgt
    53761 tactctatca attcgccctt tactagataa aatcgctggt gctttgtcta acgggatcgt
    53821 agggtttgtc gctatcgctt ctgggatgac tggtaatgct actgctgctg atatcactgc
    53881 tcatggcgta acgactttca aagcttatgc attctatgct cctgctgctt tgatgatttt
    53941 ctccgctatt atttttgctt ggaagattac attgacagag aaaaaacatg cacaaatcgt
    54001 tgagaaattg gaaaacaaat tggctccagc tgatacaatg gaagatgaac ttcacgatgc
    54061 agtagttcct tcccattaag aaaggatctt gaaaatgaag attacagaaa aagattttgg
    54121 ccaaggttat cacttgataa ccttggagaa caaaaacaag ctagcacttt ctatctctga
    54181 tttaggtgct agaatcgtca gtttaaaatc aaatgatcga gaattagttt tgggatttga
    54241 caccgctgaa gaatatatcg aaaaagatcc gtatatcggt gcttctatcg gtcgcaccgc
    54301 agggagaatc gaaaatggcc acttttctct caatggaaaa acttaccaat tagccacaga
    54361 tccaaaaact ggacataatc tgcatggtgg tgctcctgga tttgaattaa aaaaatggtc
    54421 ttatgtcatt ttgaatggcg aaaatgaagc ttctgtcatt tttactacta caagtcccga
    54481 cggagaacat ggttttccag gtacaatgga tgtggaaatc cgctatactt tgacaaaaga
    54541 taatatctgg cgagtgacct ctcgcggcac cagtgaccaa gatactttat tcaatccgac
    54601 aaatcatgtt tacttcaact tgacgggaga tgcttctcag tcaatcgatc aacatgagct
    54661 ttggctcaat agcgaagctt atgctccttt gcgaacagat agtattccta taggggtaaa
    54721 agaaaatgct gcaggaagtg ctttcgattt tcaaatacct aaaaaattag cgtccgtttt
    54781 tgctagtgat ttggatcaaa aaaatcttgt tgacggaatc gatcatccat ttttcttaaa
    54841 agaaaccggc ttgggtaaag aagccgctcg cttgactagc cccgataaaa gaatccaagt
    54901 agatattgct acagatgctt ctagtgtggt tattttcact gcaaatttcg gcacagaaac
    54961 accagaaatg cgcaaccgaa aactggcaca tcacggtggc atcacatttg agactcaaac
    55021 agctccaggt gcagagcgct tctcagcatt tggttcgatt catttaaaag ccggatcagt
    55081 atttgaaaca gtgacagaat tcaaaatcaa aacaagaaag gaataactca tcatggaaat
    55141 caaaagaagc ttaaacacaa aatttgccga aacattcgga cctaaaaaaa ctacacaata
    55201 cttctcacca ggacgcatca atttgattgg tgaacacaca gattacaatg gaggccatgt
    55261 cttccccgct tccatcactt atggaacgca aggtgtagca gcacctcgag acgataataa
    55321 aatattagtt tattccacaa actttgacga tatcggtgtc attagtttta ctttagatga
    55381 gctagaatat gataaaaaag caaactgggc aaattacgta aaaggaatgg tccttaaatt
    55441 aaaagaagct ggacactcaa tcgatcatgg gtttgagtta ttagtggaag gaacaatccc
    55501 taatggtgca ggactttcca gtagcgcttc attagaatta ttagtaggtg ttgtattaga
    55561 agatctgttt gatttaaaaa cagatcgctt ggaactagtc caaacaggta aaaaagtaga
    55621 aaatgaattc atcggtgtca attcaggtat catggatcag tttgccatcg gcttcggtga
    55681 gctagatcat gcaatcttat tagatacaaa tacgctgaaa tacgaaatgg ttccagtgaa
    55741 actagatggt tatgcaatcg tcatcatgaa tacgaataag cggcgggaat tggcagattc
    55801 aaaatacaat gaacgccgta gcgaatgcga agaagccttg gcacgtttgc aaaaaacttt
    55861 gcctatctct tctttaggag acttagatga agaagaattt gaatcaacta ttgaccaaat
    55921 cggcgatgat acattgatac gcagagctcg ccatgccgtt tctgaaaatc agcggacttt
    55981 gaaggcaaaa gctgaattag aagctgggaa cttagaagca tttggtcaac tgttaaatga
    56041 ttctcaccac tctcttcgct atgattatga agtaactggg atcgaattag atacactagt
    56101 agatgctgct caaaaacaag aaggtgtctt aggtgcacga atgacaggag ctggatttgg
    56161 tggctgtgcg attgctcttg tcaaagaaga aaatatacct gccttcaaaa acaatgtcta
    56221 tgatgaatac atgaaagttg tcggctatgc tccggaattt tatgttgcac acattggaaa
    56281 tgggacaaca aagatcgatc cagaagctgt tcatgtttga taaaaaaatc aacgatctca
    56341 gctaaaaaca aatagataaa aataacctct cagcaatttc caaatgtgag ccttttgctc
    56401 gtatttgaaa attgctgttt tttattgaca cggaaagaga acgtgtgttc taattgtgtt
    56461 gaagaggtga ttgttatgtg ggcgaatcaa aatccggtat ttgtttatga aaaagaacct
    56521 tcaagagata ttttatgtat tgactgcaaa tctttttacg cctccgtaga gtgcgttgaa
    56581 aaggatcttg atccccttac aactaaatta gtagtcatgt cctatccgtc cgattcgaca
    56641 gaaacacggg gtagcggatt aatcttggct tccagtcctg cagcaaaaaa agcttacggc
    56701 atcaccaata tcagccgtgc cagagatctt cccttcccct atccaagtga tttatatatt
    56761 gttgccccaa ggatggccta ttatatggaa aagaacagag aaatcaattc tatctataaa
    56821 aaatatgcag acgaagcgaa ccatcatgtc tattccgtcg atgaaagctt ccttgatgta
    56881 acaaatagca tggcactctt tggtaaaaca aatgcgtacg acatggctaa actgatccat
    56941 aaagatgtgt ttgagcagac cggaatctac acgactatag gaattggcga taacccgcta
    57001 cttgctaaac tagccttaga caatggctca aaagacggaa agcaaatgtt tgctgaatgg
    57061 cgttatgaag atgtaccaga aaagttatgg aaaatctcag atatcactga cttttgggga
    57121 atcggcaaac gaacagcaaa acgtctgaaa caaatgggta tacattctgt ttatgattta
    57181 gctcacgcgg attattatca cttgaaaagc aagctagggg tcatcggtac tcagctttat
    57241 gcccatgctt ggggcatcga tcgaagtttt ttgggacaag aatatacacc aaaatcaaaa
    57301 agtatcggaa atagtcaaat cctagataga gattatacaa gacgagaaga aatcgagatc
    57361 gttatcaaag aaatggccga ccaagtcggc actcgcttga gacgatctgc agcaaaaaca
    57421 caagtagtca gcttatgggt aggatactct ttaggctatc ttgatccaaa tggcaagacc
    57481 gggtttcacc agcaaatgaa aatcgaagcg acaaatgcta gcagagatct agcagatgct
    57541 ttattgacca ttttccacca gcattaccac taccaggata ttcggcgtgt aggcgtgaac
    57601 tgttccgacc tcgtatacgc gacaggttta cagcttaacc tttttgaaga tcctgaaaag
    57661 cagataaatg aagcgaaagt tgattttgtt gtcgatacga ttagaaaaaa atacggcttt
    57721 caatcaatca tccatgcgca tagtctcttg caaggaggac gcgccatcgc acgtagttct
    57781 ctcgttggcg ggcatgcagg tggtatgagt ggattagaag gtggaaaaga tgagacggac
    57841 agcaaaaaaa ttcattgact ataacgagta tcgagatcgg ccatttggat taaaatgggg
    57901 gactgctttt gcgatggaag aactagtcaa cggtatcaaa aaaaatgaag aagaagcacg
    57961 caaacagcct cttcctaaac aacaaatgac attgcaagaa atcgatagta tactgacaga
    58021 agccttttta tctcgtaaag cagtaatcat tcagctcaat ttaaaagatg aatttggaag
    58081 actcttggat gaggtcgaag ggcacttcat tggtgaagcc tatgaagatt actttatgat
    58141 tgaccatcag ccgatattgt gggaagacgt acggtatatt gagttaaagg aaacaaaaaa
    58201 atggtttgtg acatgagagg ttgtgacaga agtgatcaac ttcaaaaaat aagaaaggat
    58261 ttttcgaaaa ttgcttctta aatttttgtg gaattttggc ttatttttcg aagaagcaac
    58321 ttctggaaca acgtatatta gatatcagag gttgtgaaaa agtcgcttag ttttgagtaa
    58381 caagccaagg cgctgatttc acaacctctg tctatctatc catctattcg gtaagattca
    58441 tgcatgacgt cttctttatt tagtatgtag agcccttttt cttctgacca ttcaacataa
    58501 atcagctgtt ttacatctgc atagccttct ttcttcaagt tctccataag ccatgcttca
    58561 gtcaattgat tggactgaag cactttatgc tgaatttgcc cttcatctac aagcaggatc
    58621 gataaagctt tgtcttcatc tgattttttc aatacactca tttgaccggc attctctagg
    58681 ataacatgtt tggcattttc aagaaaaaag cattcttgct gtcttaagat tgctcgcaac
    58741 tgctccatct cgatatggtt atttgtcaac tctgtcatgt tgatgacgcc gtctttgatt
    58801 agaacagatg gctcgccttt gacccaacga ttgacctttt catttttttg gacgatacgt
    58861 tcgataccat aaatcattac tgcccaaagc gcaatggcaa ataggacatg ccctacatgg
    58921 acattgtcat cataggttga ttcttctaag atcccaccta aaacaagcgt atagactaaa
    58981 tcaaacggtg tgatttctga catggatttc ttcccaagca aacgtaccac taataataaa
    59041 ccgatcaacc cgaacaccag tttcattgta attgaaaaaa tcattttttc tccccctaac
    59101 tatctgttaa ttaaattata tatgctttct cacgaacacg catggaatat acaaggaaga
    59161 aatgtatcct tttactaaaa aaaggactgt gacactgtag tgacccccaa aagttagact
    59221 tttttggagt ggagaaatcc actccttttt tttatgctct aaaatgatat ttttacacaa
    59281 ccgttacggt tgttttacga aattggacga gactttgcca gtttaatttc tgttttatcc
    59341 gttcattatt gtagtaatag atatagctat cgatggctga ttttaattcc tcgaaacagt
    59401 tataaacttt cccgtgaaaa atctcttgtt ttaataagcc aaaaaaattc tccataagtg
    59461 aattatctaa gcagttccct ttccgagaca tgctttgaaa gattttgtac tccttcaatt
    59521 tgtttctata agctttcatt tgatacgccc aaccttgatc tgagtgaaac gtacgacgat
    59581 agggacaatc gttagtggtc tggatagctt cctccaaacc ttccattacc gctaatgcat
    59641 tgggcttttc agagatacga taggataaaa tctcactatt gaacatatcc ataaaaggat
    59701 ctagatacaa tttcttttga cggataatgc ctttggcatc cacttcatgg tatttaaatt
    59761 cagttgtatc cgtcgtgatt ttctgatggc agatactggt gtagaaacga cgatggatcc
    59821 gatttttggc tactgctcca acttttcctc gataagaatt gtagcgacgt gatttacgcg
    59881 tgtatgccgt tacttttatt cctagcttct tgatcaagcg ctgaactttc tttttattga
    59941 tagagaaacc gcggtttctt agttcattgg tcatccgtaa acagccataa tccttgtgct
    60001 tctcccgaat tttaagcatt tccgcttcaa tctcttgatc tggattttta cggtccaatc
    60061 gcctttgcca tccaaataat catgaacgat ctttaattta agttcaaaag tatatttaac
    60121 cataaaaaat accgacctcc aaaagttaga ttttttggtc taacttttgg gggtcggtac
    60181 acaaatcgtg tcacagtccc ttttttgaaa ataaacggtg ttcaaaagct tgcatctgcg
    60241 gtaataagtc cagccaagtt aaaaacataa gaagctgttt ttacttggct gttcttatta
    60301 cttgatgcaa ggcagctttt tcacaacctc ttttcaaata tttcgttttc ttattctaca
    60361 aatggttctt ctcctaacgc ttgttgagcg gctagattca acatgctcca ttgtcggtca
    60421 aagcctggct ggaagaagaa gtcagcttct gctagttctt ctaaagtcag tttgttttgg
    60481 atcgctagtg ccaatacatt tccttgacct gtaacatcat aggtagataa tactgctcct
    60541 cctagcaatt gatgggtcat tggatccgag aataattgga tggacacttt tggatttcct
    60601 tgttcttctg gtacatattt tggtcgtaac gtatcttcat aataagacac tcgtacatct
    60661 actcctgctt ttgctgctgt aaagctattc aatccgcttg ctgcaaaatg atagtcaaag
    60721 acacttaatg cagaggaacc tacgactccg ccgaacggtt tgtttggtac ttcttcaaaa
    60781 agatgtttta ctacataacg tgcttctcta cgtgcaacag tcgctaaagc gatcggcatt
    60841 tttttgcgtg ctgggataga ataagcaagt gtagcatctc ctactgcata cacatctgga
    60901 agattcgttt gcaagtattc atttgtttgg atccagccac gttcatctaa gtcgacgatc
    60961 ccttttaacc attctgtatt tgccttcaca ccggcagctt gaatgactag atctgctggg
    61021 atttcttttt cacttgtttt gattgcctca acttttccgt taccagtaaa agcttcgatt
    61081 tttgcatttg tcaaaacttc aataccgttt tcatttaggt gttgttctaa aatatctgtc
    61141 atctcagcat ctaaataagt gcctaaaggt ctatcgatca catcaagcaa tacgacttct
    61201 ttcccagctt ttcggcttgc ttctgctgct tcgatcccaa tgtaacccgc acctacgaca
    61261 gcgatttttt taatagccgg atcatttaat ttttctttga ttttggttgc ccaattgtat
    61321 ccacgcatca agtagacatt ttctagatct gctcctggta ctggcagatt gtttggtttg
    61381 acaccagaac tcaaaatcaa tttgtcataa ggatattctt ttgtttcgtt atctgatgcg
    61441 ctagtaaccg ttactgtttt tttatcggca tcgatcgttt ttacttcgtg attatttaaa
    61501 atatgaacat tggattgcgg aaagttttct ggtctgaaat tacgtacatc atttacatct
    61561 gttaccttgt cttctaaata cagctccata ccacatgaca tgaaggaaat atagtctcct
    61621 gcttcaaata gcgtgatatc tacattttca ccgtatcgtg tcaatagttc caagatcgat
    61681 tgatgccctc catgagatgc acctacaatg acaactttga ttttttccat tgatgaaacc
    61741 tccttgaata ttcttttaaa atcattctaa acaatttaaa cttaacatta cattagttat
    61801 gaatcaaaag aaacgcgttc atttgaacta aatttaaaaa acaatcgtct ccttgcagaa
    61861 tataccgcaa aattaacgat tgtttttttg ataaaatcta tgaatcactg ttctgttaaa
    61921 aagtctttga tccgtttgca ggcctcatgt aatttttcca tgctgctagc ataagaaatc
    61981 cggatataac cttctccttc tgggccaaat gcaattcctg ggatacacgc aacttttgcc
    62041 tgttccgcta attctacaca aaactgccaa gagtcagttt gaatggcagc tgggagtttg
    62101 caaaacaagt aaaatgcacc gtttggctgg gtcacttcaa atcctaaagg cgccaattgc
    62161 tggaccagat agtctcttcg tgtttgatat tgctctttca tattctcgct atctttcacc
    62221 ccatttatta gcgcttcagc cgcagctttt tgcgacatcg ttgtagcggc agtcaccaga
    62281 tattgatgga ctttaattag ttcgtcaata agggcttttt gagcaaaaat aaagcccact
    62341 cgccaaccag tcatcgcatg tgacttggat aacccgctta tcacgattgt ttgttctgga
    62401 agataagtag ctatggacat atgcgttcca ctataagtca attcagcata tacttcatca
    62461 cttataacaa ataccggata tttttttaaa acctcagcga ttgctttcaa ttgttttgca
    62521 gacaatgtcg tcccagtagg attgttagga tagtttaaaa tgactgcttt gacagctgat
    62581 ccatattgtt caaatgctcg ttcaaattgt tccggctgac agacaaaccc tgtgtcagaa
    62641 gtatctatcg ggatcaattc agcaccagct agttccacta atggctgata tcctgaataa
    62701 gcaggcgctg gaataagaac cttgtctcct tcttccaaaa cagataacaa cgcagaggca
    62761 atcgcttccg ttgcaccaac tgtcgtcaaa acttccgttt gcggatcata agttaatcca
    62821 taacgctgtt gctgaaatat acaagccgct tcccgcagtt cctctaatcc tctcattccg
    62881 gtatagtgag aaaagtcttc ttcaatcgct gctattcctg cttgcttgac atgttcagga
    62941 gttggaaaat ccggttctcc cagggtgagt ttgatcacat ctggtatcga cgatatttgc
    63001 tgatcgaatt gtcgtatttt tgatacttct attctagaaa gcctaggact aaatcgattg
    63061 gataaattca tcattattta ctcgctcctc ttttgaactg ctatcgattt ttacaagaag
    63121 attttctgta aaaagaatcg ttttgtacca ttctacacca ttttctaaaa catccatatc
    63181 aaaatcgaac gtcggatcat gtaaagcagg ggtatcaccg acacctaaaa agaaaaatac
    63241 acatggatat tgttgcgtat atatgccaaa atcttcggct tgaagaactg gagcatctaa
    63301 ttcatgtagt ttgtttgaat ctaacagtgc tgcatataag cctctatggt tgattacagc
    63361 tggatagccg tcattatagc gaaaagaaat agtagctgta gagtgaaact gttctgctaa
    63421 atggtctaat cccctcttca aataattttg catatctgaa ctgtaagaac ggatacttcc
    63481 ggatacaata acttctccag ctaaaacatt tcggatcgtt ccaccttgga tttggccaaa
    63541 tttcattaga tgattccact ctgccggtaa ttgccggtca aaatcataaa cattcttcaa
    63601 aaatcgtaca gctgcctcca gactatcgat tcctttttca ctagaagcaa tatgtgcaga
    63661 ctggccttta atgataatgt ctgtttcact gctttgtgcc atcaaaggtc ctggtcgaga
    63721 gaaaacttct cccttagcta gtccaggcca tagatgaaag ccaaatattg cttgtacttc
    63781 atatttatcc aacaatcctg actgaataac gctttgtgcg ccaccggaaa tttcttctga
    63841 tggctgatag atcagtacta cattataaat aagatcctca atgtgtttag ttataaagtc
    63901 agtcaaccct aaaagcatcg ccatatgtcc gtcatgacca catgcatgca tataaccttc
    63961 atgcttagaa gcaaaagaga gattcgtttc ttctttgact ggcagtgcat cgatatctgt
    64021 tcgaaaagca atcgtttctt cttgctgatt atcaaaataa aggagtagtc ctgtttcgcc
    64081 gatttcatgg ataacggcct cgctgttttt tacttgttca tataaatatt tttttgtctt
    64141 gaattcatga aacccgattt caggaatttg atggagtgcc attcgatatt ctttcagcat
    64201 ccgtattcac catcccttca tagataccct tcactactgt ttcatattga ttattcggta
    64261 caccgatgat cagattcaac tcctgtgctc cttgtgataa gatcgatgtg cgaatttcta
    64321 atttgttcaa tatcgataac actttcccag ataatccaat caattcttta tgcggacccc
    64381 caacgacaga gatcaaagct aagtcttcga tcacgacgat ttcttccacg ccaagtgttt
    64441 cttttaattc tttcgtgatg agaaataact tatcggcaat cgcttctgct gagacgatca
    64501 ctccgatatt gtcgatccct gaaggaatat gttcgattga tatctcatgt ttagcaaaaa
    64561 tgctcattgc tttccagata aacccgattt catcggacat atgacgtttg aataaagtga
    64621 tggaaagaaa atccttgcgt ccagctattc ctgtcagtcc attttccttt tctatttcgt
    64681 gattcgatat ttttgtccct tgagcgaaag gatcattggt attttttatt tggatgggga
    64741 tatcagcctc ttgaactggg aaaacagctg cttcatgaag aacgttagcc cccatataag
    64801 ccatctctct cagttctcta aaagagattt cctcgatgat tttaggatga tcgatgattc
    64861 gcggatcagc catcatgatt cctgaaacat ccgtccaatt ctcataactt tccgcttgca
    64921 acatcttcgc cagtatcgcg ccggtaatgt cgcttccccc acggcccaat aatttttctt
    64981 ttcctgcagg gttcgccccg taaaaccctg gaacaaccat tttcggatat cttttaaatg
    65041 cttttgtgat ttcctgtgct gttttttcct gatcgatttt cccatcatag tcaaagaaaa
    65101 tcaggtcttt tgcgtcaata aactggtaac caagatactc agccatcagt tgagcagtca
    65161 gatattcacc tctacttact aaataatctt cagttatctt ttcgtcttcc agttgtttct
    65221 gtatgcgtgc tagttcatct tcaataggta actgcagggc aagaacatct cttacttgaa
    65281 tgaaacgatc acaaatcctt ttccaaaggg gtgtccaatc aacatgatgc tgaaggtaag
    65341 cataaatcaa ataaagtaag tctgttactt tgtcatcatc tgacgtacgt ttgcctaaag
    65401 cagaaacaac gatcacttgg cgattgggat ctgaaagaac aattgtacgg acttttttga
    65461 attgctcttc atgagacatc gatgttccgc cgaatttcgc tactttcagc gtattactca
    65521 tcttgccacc tccgctattt tctgcattaa agctgcagca atctgtacgg cattcgcagc
    65581 ggctcctttg cgtatgttat cggcagtcgt atagaacaac aatccgttct ctaaagaagt
    65641 gtcttttctg atcctcccaa cataaaccat atctgttcct ctagcaagaa tgctcgtcgg
    65701 atatttatgt gctgctagat catcttctaa ttgaatccct ggaaactggc tgagacactc
    65761 tctaatttct tccgtcgtaa actctttttg cagttgaact gccacagaga ctccatgtcc
    65821 attttcgatt ggcacacgta cgcaggttgc tgatactggc aaagcaggct gatgcagaat
    65881 cttacgggtc tcatttatca ttttctgttc ttcttttgta tacccatttt ccaaaggctg
    65941 atcgatttcc ggaatcaccg tttggctaat attataagga tacaaaactg gttcctcgtc
    66001 attttgcgta cgatgaagat cttcaatgcc tttttgcccg gaaccagaaa ctgcttgata
    66061 ggtcgaataa ttgactcgct ggataccaaa ggcttcttgt aaagctttaa gcggaagtac
    66121 cgcttgaatg gttgaacaat ttggatttgc aatcagccga ttcaatgtat agtcttccag
    66181 attgacctct ggaacgatta atggaatatc cgaatcttcc cgccatgctg aggaattatc
    66241 tatgacaaat agtccctgac ttcgtgcgat tggcgcaaac tctttggata cagaagcacc
    66301 tgcagaaaat agcgctaaat catatccttc aaatgaagtt tctgtcaatt cctgtacagt
    66361 gtgtttcttt ttcttgaata cacaaacttt accggctgaa cgttttgaag ctaataattt
    66421 caatcgtcct actggaaaat catattcttc taacactttg agcatcgttt ggccgactaa
    66481 tccggttgcc cccacaatac aggtatctat ttcgcgcatt tttctccatc tcctctataa
    66541 ttcgcgtaac gcagcaatca atgctgtatt ttcttttgtc tgatcatcac ttatttttaa
    66601 tacacgtgca ggtattccac cgacaacagt ttctgctgcc acatcttcta aaaccactgc
    66661 tcctgctgcc acgactgcat cttttccgat atggacacct tcaacaatca ctgcattcgc
    66721 acctaccagt acgccgtctt ctacgataac cggtttggcc gatgctggtt cgatcacacc
    66781 tgctaagaca gctcctgcac caatatggca gtttttgccc actgtcgctc gtccacctaa
    66841 gacagcaccc atatcaatca tcgtgttttc accgattact gcaccaatat tgataatcgc
    66901 tcccatcatg atcacggcat tgttgccgat tgacacttga tctctgataa tagcacctgg
    66961 ttcgatacga gcattaattt ttttaatatc tagcaaagga actgcgctgt atcttgcagc
    67021 agtttcgatt tcgatttcaa tgattttttc tgattcagct tctaaaaccg gagcaatcgt
    67081 ctcatagtca ccaaaaacaa cgaagctgct tccttcacca aaaactttac tttctttaaa
    67141 ttcgattggc tcggttacat tcagatagac tttcacaggc gtctttttag atgccgtttg
    67201 aatgtagcgg atgatttctt gagcttccac gttttttaca cccctttgtc cattaataaa
    67261 tcttctaatt tgtaataacc tggtgactga tctttcaacc agtccgctgc ttctactgcg
    67321 cctgcagcaa agattcgatt agaaaaagat tcatgtttga tcgtaaatat ttcatcagta
    67381 gcagcaaaca atacatcatg ttcaccaggt aaagaacctg cacgaatact gtgtacacca
    67441 atttggtttt cttctctttt tttcccttgc cagttgtata cgggctgcag cttttgcact
    67501 tcttggattg tttgaagcag catatttgca gtaccagatg gtgcatcttt tttacgacta
    67561 tgatgttttt caatcagttc gatctgccag ccttgcaaca ttgcagctgc ttgcttgatt
    67621 agttgattca tcaccatgat gccgaacgaa aaattagcac tatacatcac aggtacatgt
    67681 ttggcatgtt cttttatttc ttggaactgt gattgtgtat aacctgtcgt gccaatgact
    67741 aacggaagtt gatatgataa gctatacgaa aggattttct ctaaattatc tggatgagaa
    67801 aaatcaataa gcagttctgg cagttccgta aaagcaagcg tagttgcttc tttaggtgcc
    67861 gtccgtaaaa gaaggaccgt atctcctctt tcttgtgcaa cttcttcgac tctatttccc
    67921 atctgtccac tgccaatcag tccgattttc atttttcaac cgtcctttct tttaacaaaa
    67981 gctgagctaa ttgtttcttt ttctcttttg aaagagaaac taaaggcagg cgtagaggtc
    68041 cggaaggtaa gtctaataat gacatggctg ctttgacagg aataggattg gtctcactga
    68101 acaaggcatg gatcagttca agtgcattta attgcttttc ttttgcttgc tgccatcttc
    68161 cgtcctgcgt atcttttact aattcatgga ctattttagg ttggatattc gcccatacac
    68221 ttattacacc gcttcctcct acactcatta ctggtaggat caaatcatca tttccactgt
    68281 aaaggaagaa ttcttctcca atcaaccgag cggcatccat cacataagcc atatctcctg
    68341 aggcttcttt caaaccaatg atattaggat gttctgctaa atttactaat acatggattg
    68401 gaatcgacat gcctgttcta gaaggaacat tatacaaaat aagcggaatc ggtgaggctt
    68461 ctgcaattgc tgtaaaatga gcagctagtc ctgcatcact tgttttgttg tagtaagggg
    68521 tgatgaccaa aagtgcgtct gcccccaaag aagcaaaatg cttcgctttt tcaatcgttt
    68581 ctttcgtatt attcgttcca gctcctgcaa tcaccggcac acggccagcc actttcttta
    68641 ctgtcagttg aaggatctgc tcctcctcag attgtgtgag cgtagaagat tctcctgttg
    68701 tacctaaaac taataatcca tctgtttgtt catctaaatg gaattggatc aatttttcca
    68761 aaccagcata atctactgat ccctcttcat tcatcggcgt gatcagcgcc acgatcgaac
    68821 cttttatcat cttcattcct ccaatattct tgtccattca tgaactgctg ggccagccat
    68881 ttgtatcgca tcctcaccag agatcatcaa gtctccttgt tccaagtgaa caactacctg
    68941 atctgctgaa attttcccag tttccttagc aaccacataa gaggcacagc aacctgtacc
    69001 gcaagcaagt gtccaaccta ctcctctttc ataggtacgg acgatcaatt cttgttcatt
    69061 gactacttct acaaagttga cattggtttt ttctttgaac aaaggatgat gacagatcag
    69121 ttcacctctt tttctccaga cttcctcacg cgcattttca acaaaaacaa cggtatgaat
    69181 cgttcctaaa aataaactag tgatcgttac tttttcacca ttgatctcta tttcctggtt
    69241 ttttattgga taagtttgat tagctttgat tttttccgga gaatcatctg gcactcccat
    69301 atctacgctg caataaaaag gtgagggatc caacaccgta atttttcttg tgcctgctaa
    69361 tgtctctacg ttgaattcct gttcattcat catgttctga tcatttacgt atcgagcaaa
    69421 acagcgaatg ccatttccgc acatcggcgc gcggctgcca tctttgttgt aatagatcat
    69481 ttccaacgga tcgattttta cggcgatcaa tccgtctata tcatattttt cttttgtgca
    69541 taaagaagcg gctaattgac tataatctgt gtcttctgcg taatctaata agataaaatc
    69601 atttccgcag ccattatatt tatgaaggat cataggaaac ttcccccctt agtagatcag
    69661 aaaatgcttg tctgcgaaca atcagtcttg attggccatt attgacaaaa acaactgctg
    69721 gtcgtgtcgc tcgattgtag ttgctgctca tcgagtatcc ataagctccc gtggaataaa
    69781 cagctaaaag atcacccgat tctgctttcg gcaaataagc ttctttaatt accacatcgc
    69841 ctgattcaca catttttcct gcaatcgtca ctttctctgt tttttcttcc gacagttttg
    69901 ctgctaaatc acaatcgtat tctgcctgat acagagctgg acggatatta tctgtcatcc
    69961 cgccatctac aaagtaatat tttttatgtg gtgtcttttt gatgaaacca atcgtgtata
    70021 gtgttgtacc agcttctcca acaatacttc tacccggttc gatcagtaat tgacgaatgg
    70081 tcagttttcg tttttccaaa gcttcttccg tatattcaat cagttttttt agtgcctctt
    70141 cgactgggat cggctgatca ttttgtgtat aacgaatccc aaaccctccg ccaagattca
    70201 aggaaagagg ttggtcaaaa tcggttaagt aattcgtcaa tttgtcgatt tcagctaacc
    70261 aagcagtaac atcaaaaatt tgtgacccga tatgagcatg aaatccttct aactctagat
    70321 agctgctttc ttttatcaac tgaagggctt gttggcactc tttactttca tagctcatgc
    70381 cgaattttga atcaatatgc gcagtgacga tatattcatg agtatgtgct tctactccga
    70441 cattcaaccg aagcatgata caaatttttt ttaaatagcg ttggcttaat tctgctaata
    70501 attcaacttc catcaaatta tcggcaacaa tatgcaacaa atcattttca agtgcataga
    70561 tcagttcctc tggcgtcttg ttgttaccat ggaagtagat agtatctcta ggaaaatcag
    70621 cttgcaaagc ggtatagatt tccccaccac tgacaacatc tagcccgaat ccatattcac
    70681 gaactaaatg cagcatctca atcgtttgga atgctttaga ggcgtaaagc acttttgtat
    70741 caaaacgttt cgatacaaag cctcgcttga atgacagcat cgtttgtctc atcttttctt
    70801 catcatacac atacagaggt gtcttatact tttctgccaa tgtgcttgct gtgactccgc
    70861 caattatcaa ttctgtcatt ttttcattcc tcttttcact ttttttccgt ttttattgga
    70921 atttcatttg ataaagattt gaattttatt ggaataatat taaacaaaat tttctgaatt
    70981 gtctagtata tttcgaaata tttttttaaa aataagaata aaaatggtta taaaaacaaa
    71041 atacccgaac tattagaagc tatttataca taaaaacata aattcaacac tatttagtga
    71101 tgaaaaaata ttttcgcttc aatatagttc ggaatagttc ggatattttc aattttatga
    71161 atcatttcaa tttcttcata aataagtgca gttttttctt tctctagctt ttgccattca
    71221 tctttcaaaa tataaataaa atcaaatact tttttatttt tcaatttgct gattccacaa
    71281 aaaacctctt gaaaggcaga tccgatgatc tgcctttcaa gaggtcaagc tctgttttca
    71341 aattcttatc aatccgttag cgaattattt tgacgcacgt tttacataag aaccttctgc
    71401 tgtattgatt tccaacaatt catctgtttc gatgaagtca ggaacattga ctactaagcc
    71461 agtttccatt gtcgctggct tacctgaacc agtgactgtt gcacctttga tggaaggttg
    71521 tgtttccaca acacgtaata cgacagttgt tggtaattga acgccgatga cttcgctacc
    71581 gaaaaattgg atttttactt ccatgttttc taggatatat ttcatttctt cttctactgt
    71641 ttctacagga atttcatatt gctcatatgt ttccaaatcc atgaagaaag ctgtatcatc
    71701 catcgtgtac aaatattgta caggttttgt gtcgatatgt gctttttcaa atttttcttc
    71761 tggtctgaac gttgtgtcgt atgttgcacc tgaacggaca tctttcagtt tcatacgcat
    71821 aactgtattt cctttaccag gtttatggtg gcttgcatcc agaactttaa tcagtttgcc
    71881 gtcttgtacg aaagtcatac cggctcttaa atcacttgct gagatcatta tttttgctcc
    71941 ttcttttctt tatcataatc aactttattg tatcagacaa ccggccagaa aactagagta
    72001 ttctctatct tttaaggtct catgcctatt tgtcagaaaa ataaacacgg gtaaacgatg
    72061 ctatcgaaat atttttttct ttcaagcctt tgacttttat tttttttcat gctatcgtta
    72121 ataaaaattt tacttggagg gatacacatg acagtcagca accaaaaaca attgaatcgt
    72181 tgctgttgta tggtgcataa aagcagcata ctatttgtca tgtctattaa ttgcccttca
    72241 tagaatgagt accaggtaac ttatcttttt atctactcaa tttttctcta tgtctttcaa
    72301 ggagctgatt taatagtcag ctcctttttt tattatcttt ttttaggagg cccacatgat
    72361 tatctcgaca attacagaag ctattggttc cacaccgctt tatcgctttg acaatcagca
    72421 ctattctatg cctaaaggtt ctgctattta tgcaaaacta gaatatttaa atcctggagg
    72481 aagtatcaaa gatagattgg gcagttattt gatcaaagaa ggatttgccc aaggaaaaat
    72541 caatgaaaaa acgacgatca tcgaaccaac tgccggaaat acaggaattg ggatcgctct
    72601 ggccgcactc acatacaaat taagaacggt ttttgttgtt ccagagaagt ttagcttaga
    72661 aaaacaacaa ttgatgaaag cattgggagc aaagatcatc cattctccta gtgagcaagg
    72721 aatcatcggt gccatcagca aaagtaaaaa acttgcagag gagatatcaa acagctatct
    72781 gcctcttcaa tttgaaaata aagataatcc tgctgcttac tatcatacgt tagggccaga
    72841 aatctttcat gaaatcaaag aaaatatcca tagttttgta gcaggaattg ggagtggtgg
    72901 aacctttgct ggaacttcta cctttttgaa agaaaaatat cccgacattc gaataatcgg
    72961 tgtagaacca gagggctctg tgttaaatgg tggtgatcca gcccctcacg aaattgaggg
    73021 tatcggtgta gaattcattc cgccgtttct ttctcccctt tcaatcaatc agatcgagac
    73081 aatctctgat gtagaagggt ttaactatac taggcagtta gcacgagaac aaggactatt
    73141 agttggaagt tcgagtggtg cggcttttgc agcagcatta agagaaattc gtcgtttacc
    73201 acctggtcat cgtgtcgtta cgatttttcc agacgcagca gaccgctatt tatcaaaaaa
    73261 catttactta taggaggaaa gaaacatgca cattcaaaca aaattgatcc acggaggcat
    73321 cagtgaagat cccacaacag gagctgtcag tgtacctatt tatcaaacat ccacttatcg
    73381 gcaagatggc gtcggccagc ctaaacaata tgaatattca agatctggta atcctactcg
    73441 ttttgcattg gaagaactga ttgctgattt ggaaggcggt gttcgaggat tcgctttttc
    73501 ttctggtctt tctgggattc atgccgtttt ttctcttttt caagctggcg atcatatctt
    73561 attaggagat gatgtctatg gaggaacatt ccgtctattt gacaaagttc ttactaaaaa
    73621 tggtctcgag tacacgatca tagatacgag taatcttgat aaaatagaac aatccatcaa
    73681 acccaataca aaagcacttt atcttgaaac acctagcaat ccgcttctaa agattactga
    73741 tttagaaaaa agtgccactc tggctcatca acatggattg atagttattg ctgacaatac
    73801 atttgctact ccttattttc aaagaccttt agatctcggt tctgatatcg ttgtccatag
    73861 cggtaccaaa tatctaggcg gacacagcga tgtagtagct ggtttagtga cttctaacca
    73921 taaagatcta gccgatcaga tcggatttta ccaaaatgct atcggagccg tacttggtcc
    73981 ccaagatagc tggttacttc agcgcggaat caagacacta agtgttcgta tggaggaaca
    74041 tcaaaaaaat gcttttgtgg tagctgattt tctattttct catccagcag tagaaaaggt
    74101 ctactatcca ggattacccg atcatgaact ccatggagtt gctaagcagc agatgagcgg
    74161 ctttagcgga atgatttctt ttactttaaa aaatgaagaa tctgctattc catttgttga
    74221 atcactccaa ctatttactt tagcagaaag tttaggtggc gtagaaagtt tagtggaaat
    74281 tccttctgtc atgactcatg cgtctattcc aaaagaaaaa cgagaagagg ctggcataaa
    74341 ggacggcttg atccgtcttt ctgtaggaat tgagtatggt caggatctca taaacgattt
    74401 agctcaggca tttgacagaa tcaagaacta gaagtcccaa taaacgactt agcagaaaaa
    74461 tctaaaaaat atttcagatt gctacacctt ggaaacgata agtgttagaa tcaagtagaa
    74521 agacgttttt gtaaatttca ctaaataatt ctttagtgaa aagcatcaaa acgaatgaac
    74581 aaacagatag gagtcttaca aatgagaatg aatgtcgaaa gttttaatct tgaccataca
    74641 aaagtcaaag caccttatgt acgtgtagct gatcgaaaaa cgggtgcgca tggcgatgtc
    74701 atcattaaat acgacgtccg ctttaaacaa ccaaataaag aacacatgga catgccaagt
    74761 ctacattcac ttgagcactt gactgccgaa ctaatccgca atcacgcaga ttacatcgta
    74821 gactggtctc caatgggatg ccaaacaggc ttttacttga ctgtattgaa tcatgaaagc
    74881 tacgaagaca ttttagatgt tcttgaagca acaatgaaag atgttcttga agctactgaa
    74941 gtacctgcaa gcaatgaaac acaatgtggc tgggctgcca gccatacact agaaggtgca
    75001 caagctttgg ctcgtgaatt tttagcaaaa cgcgatgaat ggtctgaagt agaagcatag
    75061 tttctaaaag aacgtaaaga tgagaagcaa tatagctatc ttatcttcgt attttattaa
    75121 atatttattg tctgaaaaga gttctaaacg ggaaaacaaa tagctagttt tcagtttagc
    75181 gctcttttta ttatataaaa tagaaaggag aaaactttat gtctatttat aattttgaaa
    75241 ctactttaga agacggcact gtctattcat tgaaaaaata tgcaggcaaa ccgataatca
    75301 ttgttaacac tgcaacaaaa tgcggtctag cacctcaatt taaacaatta gaagaacttt
    75361 accaagctta tcagacacaa ggtctggtta tcttaggctt tccttccaat caatttaaac
    75421 aagagctaga ttcagcgact gaagcagcag aagcttgtaa aaccacttat ggcgttacct
    75481 tccctatgca tcaattgatt gacgtaaatg gagaaaatac agatcctctt tttacttatc
    75541 ttaaaaatga agctcctggt actgtcacta aagcaataaa atggaatttt actaaatttt
    75601 tgattgatag aaatggcaaa gtaatcgaac gatttgcacc acaaacttct ccattgaaaa
    75661 tgaccgctgc aattgaatcc gttctttaac ttaataaaaa taaaaaaaga tgaactattt
    75721 ctagttcatc tttttgcctt tgcgtggcga cgtcctactc tcacaagggg caacccctca
    75781 ctacaatcgg cgctaagaag cttaacttct gtgttcggca tggttacagg tgtatccttc
    75841 tcgctatcgc caccacactg tggtgttatc ttttattgag taaattttgt tcactcaaaa
    75901 ctggatttga agtca
//
LOCUS       DBGZHO010000007        66416 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.007, whole genome shotgun sequence.
ACCESSION   DBGZHO010000007 DBGZHO010000000
VERSION     DBGZHO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.007"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(112..627)
                     /locus_tag="ACN3HL_000655"
     CDS             complement(112..627)
                     /locus_tag="ACN3HL_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HHC8005556.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(809..1420)
                     /locus_tag="ACN3HL_000656"
     CDS             complement(809..1420)
                     /locus_tag="ACN3HL_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHC8005557.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            complement(1446..2897)
                     /locus_tag="ACN3HL_000657"
     CDS             complement(1446..2897)
                     /locus_tag="ACN3HL_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HHC8005558.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            complement(2921..3652)
                     /locus_tag="ACN3HL_000658"
     CDS             complement(2921..3652)
                     /locus_tag="ACN3HL_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8005559.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            complement(3670..4065)
                     /locus_tag="ACN3HL_000659"
     CDS             complement(3670..4065)
                     /locus_tag="ACN3HL_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HHC8005560.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            complement(4167..5804)
                     /locus_tag="ACN3HL_000660"
     CDS             complement(4167..5804)
                     /locus_tag="ACN3HL_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HHC8005561.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            complement(5839..7173)
                     /gene="gmhB"
                     /locus_tag="ACN3HL_000661"
     CDS             complement(5839..7173)
                     /gene="gmhB"
                     /locus_tag="ACN3HL_000661"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HHC8005562.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            complement(7215..8324)
                     /locus_tag="ACN3HL_000662"
     CDS             complement(7215..8324)
                     /locus_tag="ACN3HL_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HHC8005563.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            complement(8349..9482)
                     /locus_tag="ACN3HL_000663"
     CDS             complement(8349..9482)
                     /locus_tag="ACN3HL_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005564.1"
                     /translation="MNVRLVTVILAIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAY
                     IYSDKTIWVKSRESMSLYYVLLAYPLFCTLINQAWNLDSMLNTICGVTFLSYILRTSI
                     SLIQKFSGVLLYENIYRECAPENWYRGGFLRINPPCFTIIIIPIALYMIERQVVARRK
                     VKYYLLIASALAYSAVIHGSRSVLVYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVI
                     FINSTMFSTFVETFTNSTGEYAGSAESRFASVWFFIPKFLQSPLFGTGILTGEEFTFI
                     LPGGVRGHLSDIGFFYTITQYGVGILIFDILFIIKGFKTALLASKVGMTGYQYLAFGI
                     TLNVLLTGINIDWFYPIFTPAIPVCLAVIEYIYQECRSVANIE"
     gene            complement(9615..10721)
                     /locus_tag="ACN3HL_000664"
     CDS             complement(9615..10721)
                     /locus_tag="ACN3HL_000664"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHC8005565.1"
                     /translation="MKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRDVPPLDPKI
                     KSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYEGGLYVLCK
                     RHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAEFPELNAKS
                     YVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMDVRKKVHFT
                     IAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAIFPYKEIYG
                     SGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKYVNLSPAEK
                     SKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            complement(10732..11505)
                     /locus_tag="ACN3HL_000665"
     CDS             complement(10732..11505)
                     /locus_tag="ACN3HL_000665"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HHC8005566.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            complement(11519..11974)
                     /locus_tag="ACN3HL_000666"
     CDS             complement(11519..11974)
                     /locus_tag="ACN3HL_000666"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HHC8005567.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            complement(12396..13502)
                     /locus_tag="ACN3HL_000667"
     CDS             complement(12396..13502)
                     /locus_tag="ACN3HL_000667"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHC8005568.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            complement(13520..14281)
                     /locus_tag="ACN3HL_000668"
     CDS             complement(13520..14281)
                     /locus_tag="ACN3HL_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HHC8005569.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            complement(14357..15355)
                     /locus_tag="ACN3HL_000669"
     CDS             complement(14357..15355)
                     /locus_tag="ACN3HL_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HHC8005570.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            complement(15374..16027)
                     /locus_tag="ACN3HL_000670"
     CDS             complement(15374..16027)
                     /locus_tag="ACN3HL_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8005571.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            complement(16037..17047)
                     /locus_tag="ACN3HL_000671"
     CDS             complement(16037..17047)
                     /locus_tag="ACN3HL_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HHC8005572.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            complement(17066..18316)
                     /locus_tag="ACN3HL_000672"
     CDS             complement(17066..18316)
                     /locus_tag="ACN3HL_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HHC8005573.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            complement(18823..19103)
                     /locus_tag="ACN3HL_000673"
                     /pseudo
     CDS             complement(18823..19103)
                     /locus_tag="ACN3HL_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697748.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            complement(19662..19772)
                     /locus_tag="ACN3HL_000674"
     CDS             complement(19662..19772)
                     /locus_tag="ACN3HL_000674"
                     /inference="COORDINATES: protein motif:HMM:NF020874.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HHC8005574.1"
                     /translation="MNPNGYEWLRAKGSYPVPKYCNYSETLMEWYQLIIT"
     gene            complement(20178..20867)
                     /locus_tag="ACN3HL_000675"
     CDS             complement(20178..20867)
                     /locus_tag="ACN3HL_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HHC8005575.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(20912..21676)
                     /locus_tag="ACN3HL_000676"
     CDS             complement(20912..21676)
                     /locus_tag="ACN3HL_000676"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HHC8005576.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(21704..22402)
                     /locus_tag="ACN3HL_000677"
     CDS             complement(21704..22402)
                     /locus_tag="ACN3HL_000677"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HHC8005577.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(22415..23194)
                     /locus_tag="ACN3HL_000678"
     CDS             complement(22415..23194)
                     /locus_tag="ACN3HL_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YveK family protein"
                     /protein_id="HHC8005578.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPIQPKATNDKTAPSRRSRSRV"
     gene            complement(23210..24154)
                     /locus_tag="ACN3HL_000679"
     CDS             complement(23210..24154)
                     /locus_tag="ACN3HL_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HHC8005579.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(24195..24974)
                     /locus_tag="ACN3HL_000680"
     CDS             complement(24195..24974)
                     /locus_tag="ACN3HL_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005580.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            complement(25359..27434)
                     /gene="glyS"
                     /locus_tag="ACN3HL_000681"
     CDS             complement(25359..27434)
                     /gene="glyS"
                     /locus_tag="ACN3HL_000681"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HHC8005581.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(27436..28353)
                     /gene="glyQ"
                     /locus_tag="ACN3HL_000682"
     CDS             complement(27436..28353)
                     /gene="glyQ"
                     /locus_tag="ACN3HL_000682"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HHC8005582.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(28739..29551)
                     /gene="recO"
                     /locus_tag="ACN3HL_000683"
     CDS             complement(28739..29551)
                     /gene="recO"
                     /locus_tag="ACN3HL_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HHC8005583.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQLMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(29694..30593)
                     /gene="era"
                     /locus_tag="ACN3HL_000684"
     CDS             complement(29694..30593)
                     /gene="era"
                     /locus_tag="ACN3HL_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HHC8005584.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(30608..31003)
                     /locus_tag="ACN3HL_000685"
     CDS             complement(30608..31003)
                     /locus_tag="ACN3HL_000685"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HHC8005585.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(30987..31463)
                     /gene="ybeY"
                     /locus_tag="ACN3HL_000686"
     CDS             complement(30987..31463)
                     /gene="ybeY"
                     /locus_tag="ACN3HL_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HHC8005586.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(31480..33672)
                     /locus_tag="ACN3HL_000687"
     CDS             complement(31480..33672)
                     /locus_tag="ACN3HL_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HHC8005587.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(33696..34667)
                     /locus_tag="ACN3HL_000688"
     CDS             complement(33696..34667)
                     /locus_tag="ACN3HL_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HHC8005588.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            35373..36752
                     /gene="brnQ"
                     /locus_tag="ACN3HL_000689"
     CDS             35373..36752
                     /gene="brnQ"
                     /locus_tag="ACN3HL_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHC8005589.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(36908..37354)
                     /locus_tag="ACN3HL_000690"
     CDS             complement(36908..37354)
                     /locus_tag="ACN3HL_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HHC8005590.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(37381..37557)
                     /gene="rpsU"
                     /locus_tag="ACN3HL_000691"
     CDS             complement(37381..37557)
                     /gene="rpsU"
                     /locus_tag="ACN3HL_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HHC8005591.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(37719..38147)
                     /locus_tag="ACN3HL_000692"
     CDS             complement(37719..38147)
                     /locus_tag="ACN3HL_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HHC8005592.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            38239..39099
                     /locus_tag="ACN3HL_000693"
     CDS             38239..39099
                     /locus_tag="ACN3HL_000693"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HHC8005593.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(39193..39543)
                     /locus_tag="ACN3HL_000694"
     CDS             complement(39193..39543)
                     /locus_tag="ACN3HL_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HHC8005594.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(39559..41286)
                     /locus_tag="ACN3HL_000695"
     CDS             complement(39559..41286)
                     /locus_tag="ACN3HL_000695"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HHC8005595.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(41500..42426)
                     /gene="trxB"
                     /locus_tag="ACN3HL_000696"
     CDS             complement(41500..42426)
                     /gene="trxB"
                     /locus_tag="ACN3HL_000696"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HHC8005596.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(42571..44004)
                     /locus_tag="ACN3HL_000697"
     CDS             complement(42571..44004)
                     /locus_tag="ACN3HL_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHC8005597.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(44004..45407)
                     /locus_tag="ACN3HL_000698"
     CDS             complement(44004..45407)
                     /locus_tag="ACN3HL_000698"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HHC8005598.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            45637..46539
                     /locus_tag="ACN3HL_000699"
     CDS             45637..46539
                     /locus_tag="ACN3HL_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHC8005599.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(46580..48466)
                     /locus_tag="ACN3HL_000700"
     CDS             complement(46580..48466)
                     /locus_tag="ACN3HL_000700"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHC8005600.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(48563..49414)
                     /gene="licT"
                     /locus_tag="ACN3HL_000701"
     CDS             complement(48563..49414)
                     /gene="licT"
                     /locus_tag="ACN3HL_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHC8005601.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(49749..51533)
                     /locus_tag="ACN3HL_000702"
     CDS             complement(49749..51533)
                     /locus_tag="ACN3HL_000702"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005602.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(51533..53284)
                     /locus_tag="ACN3HL_000703"
     CDS             complement(51533..53284)
                     /locus_tag="ACN3HL_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HHC8005603.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(53426..53650)
                     /locus_tag="ACN3HL_000704"
     CDS             complement(53426..53650)
                     /locus_tag="ACN3HL_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HHC8005604.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            53901..55487
                     /locus_tag="ACN3HL_000705"
     CDS             53901..55487
                     /locus_tag="ACN3HL_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HHC8005605.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(55796..57571)
                     /locus_tag="ACN3HL_000706"
     CDS             complement(55796..57571)
                     /locus_tag="ACN3HL_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HHC8005606.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(57782..58684)
                     /locus_tag="ACN3HL_000707"
     CDS             complement(57782..58684)
                     /locus_tag="ACN3HL_000707"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HHC8005607.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            58963..61308
                     /locus_tag="ACN3HL_000708"
     CDS             58963..61308
                     /locus_tag="ACN3HL_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HHC8005608.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(61471..61737)
                     /locus_tag="ACN3HL_000709"
     CDS             complement(61471..61737)
                     /locus_tag="ACN3HL_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005609.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(61730..62053)
                     /locus_tag="ACN3HL_000710"
     CDS             complement(61730..62053)
                     /locus_tag="ACN3HL_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005610.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(62065..63321)
                     /locus_tag="ACN3HL_000711"
     CDS             complement(62065..63321)
                     /locus_tag="ACN3HL_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HHC8005611.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            complement(63318..63713)
                     /locus_tag="ACN3HL_000712"
     CDS             complement(63318..63713)
                     /locus_tag="ACN3HL_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005612.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            complement(64067..65068)
                     /gene="ccpA"
                     /locus_tag="ACN3HL_000713"
     CDS             complement(64067..65068)
                     /gene="ccpA"
                     /locus_tag="ACN3HL_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HHC8005613.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            65278..66381
                     /locus_tag="ACN3HL_000714"
     CDS             65278..66381
                     /locus_tag="ACN3HL_000714"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HHC8005614.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
BASE COUNT        19396 a        14171 c        11130 g        21719 t
ORIGIN      
        1 tctatatcta aatttagttt tatgtattcc tcatagaaat aaccgagcat ttgctcggtt
       61 attgttcttc ttattttcca gtatccttct tttctccaca gctcatttta atcaaaagct
      121 taatctttcc acatttttgt ctttctcact tataacgaaa cactgccgac tgaccggcca
      181 ttcaatatct acgctttcat aacttataca tttggcagca ttagaattga aatcattatc
      241 tacgcaccac tgaactagcg tattgtcctc catagtaaga tagccatgag catatccacg
      301 tgggatatac gcacatttac cattgctttc actcaatgtg ttgacataca cacatccata
      361 agtggaagat ccttgtcgaa tatcaagtgc gatattcata atttcaccat gtaggcacat
      421 cactatcttt ccttgagcat gctctccact ctgataatgt agccctcgca tagtatattt
      481 attatgacta aatccttgat ttatttgctt aatgtgaaac tcaataccaa tcgagaaaag
      541 agtctcatta tccaatgcaa cagcagtata tcctctgaaa tccgaaaact taattatatc
      601 aaacactttt accataacta ccaccatgtt atatatttta ccaatttttt aattcgctcg
      661 acctcattta aagcaataaa attccctacc tcttgaagat ataacaacaa tgttttagca
      721 aaaatagatg gcatgtaaag tattcttgat gagattacac aatcctgtct gcagaaaaat
      781 attaaccata ttaaaattca aagcagttct attttaagtc tatatactta tttaatcggt
      841 agaatagcca atatagcaaa gcaccaatta agccccctag ggtgttataa aacaaatccg
      901 atagttgaaa tgtaccaagc ctaaaaaaca gttgtgtaaa ttctatactt aatgagaata
      961 aaaacacata cttaatccca acatagatgg tgcgtataat atcacattta atgtcacgcc
     1021 accataacaa taacatgcaa aaagggataa acagcatcgt gttctccacg cattctgttg
     1081 tcaatctgct ctctcctgta gcattatcta taatatataa tgaccactgt ccaataacgt
     1141 ttgaaagcgg gttcatccac atatttcgat taagcaaggt tttaaataat atcaaagtaa
     1201 aataaaacgc aagaaaaaag agtctgcgaa atttactaga tgctttaaaa tatctcaacc
     1261 agattaatac agaatctttt aagtttttag gatctcgaga gttatcaact ataaatagat
     1321 accagtacat aaacagatac gctgttaata cggcaaataa gaacggctga tataatgctg
     1381 ttaatacatt taccgttata gcagaaataa tatctatcat tctctatctc tctatgagca
     1441 aatgtttatt tgctcataat tctccttact aaaagtagca atcgttttct aaatataatt
     1501 gcagcgacac aagcaattgc tataattaaa tattttatga aatcaaattt attaattatt
     1561 gaaattagga tgccaccagc tatcgtgatt gcagaaatca aaagtattcc tctgacatca
     1621 tatatgtttt ttccatccaa tagttctttg caaacttttc tataaaaaat ataatggatg
     1681 acgcagaaaa acatatatga gaatacagtt gtgtatgcta ccgcctgata cccatataac
     1741 tttataaaaa cataatttag tacaatattc ataattgcac acaaaaccga tggaataacg
     1801 acagtgagtt tcttttcaaa gtattcctgt actctagcaa acagctgaaa catatagttg
     1861 aaataaatac cgatacatat aggtacaatt aaattaacac tgtcgatata tttctgccca
     1921 ccaaatatca acacaatttc tttactaaat agcattaatg caaaaagcat agccgctacc
     1981 aaaccaagaa cttcattagc tctttttgat agtaaatcat attctcctga cttgattttt
     2041 tgatactgat aaggtgcaaa agtggaattg acagaatttg taacaaggtt aattagagca
     2101 ccaatagaat atgccacgct gtaaatagca acatctgacg aaccacataa gtaatttatc
     2161 ataattttat cagaaccatt cagaataaat tcagataaat agtgtggcat caacgataca
     2221 caaaatacta ctgcgaaatt ccacacttca ttatccttaa aatccttaca tcttctaaat
     2281 accgatatat acacagccac gccaacaaca ccagtcacta ggacattcat taaggctctc
     2341 gcctcagcgg taggagatat aaacagaacc gctaaacagc caactacaga tgagccaaca
     2401 gtaactgcaa gggtagctac taataaagtc ttataatcat atatatatcg tttgtgtaaa
     2461 gaccaacatt gtatttctgc ctgaaatata aaatatgaga acatacagac aactagaact
     2521 ggtgtcaatc ctaaaatttc tgccaatata tccttaataa aaatagcaat aacaaaccaa
     2581 aaaatagtca gtactaaagt caatccggat actgtcgaaa gaatatgttc ttgattatca
     2641 tattttacat aaagattcat catggctttg aacaaactaa gcgatgtaat catgagcaat
     2701 aaggattccc acgatagata agtgctgtat aaaccgtatt gttctgtaga caaaactcta
     2761 gtaaaaattg gggttgtaat cattgaaacc cctctctgta aaaaaccaca taccataaac
     2821 cataatgcag ccttaacagg aagtggagta ttcttatatc tgcttaatgt ttttacaatt
     2881 agattattac tggtcactgc tattttctcc taaacactat ttattcttga ttcaaaaaca
     2941 cattgagctc ttctggagta ccaagcacat gaaccttttt cgcatctact atgctaatag
     3001 tcacctttaa cccttttttt atcataaagt tatataatgg tgctatatat ttttcattct
     3061 tctccatatt agaggagtct gcataatact cttcatataa agctttatac agctttgccg
     3121 atgagaaata atacgcacca agagtacaat tatcagaaat gcgaactttt tcgcggactt
     3181 ctattacttc atttcgatcg ttaagctttg caaaactcca atgatcgcca tcagcatgaa
     3241 agcatggaat atgtccatct ccacaaatat cttcgtattt catctcattt gattccacgt
     3301 atgtatcaat attgtaaacc ataatctcat tgtcttgatt gcaataagga atagccaaca
     3361 tacatgtagt tgcttgacca tctgtcatat agtctatttc aatcacttct acgttttcaa
     3421 taccaaagta agcacaatgc tcctttataa aagctgaagc gttgtcttcc tgacgaacaa
     3481 caaaaatata cttatcaaca tttttattgt atccaaccaa actatccatg gcccaatcaa
     3541 ataaagttct tcctttggca ttaatcatat atttaggaac cgcataacca atttttcgaa
     3601 aacgacttcc caaacctgcc atcgtaatga taactgtcat ctttttttcc atagaactaa
     3661 cctccttatt tagaatcttt tttttgaact gttgcagatt tcatttaatt catctacaga
     3721 gcatctcaaa aactcatcag gtctaaccgt tcgatcatct acatagaagc ctttatgccc
     3781 cggccaaggc ttaccataca ggatttcatc atacggaatg tcccatttat ccaaccacgc
     3841 caagagcact tttgcagtat tagcatttat cattcccaaa tttcctttat aggaattaac
     3901 attgcgtgag gtgaacaatg taattttagc accattctcc ttatagaatc tcagtttttc
     3961 aaccatattc tcatacggca ccaaatcctc atatcgctca tccttcttct ttatcggaca
     4021 caaagtgcca tcgatatcaa acacaaaaga atattcacta tacatttttc tcttcccttc
     4081 tattgtatta attaatataa tcgtgcctta atgcctacat tgctaaaaca gtattgtaac
     4141 cgttattcat taaggcacaa tttatattag agtataactt tattacttac tcttgcaaga
     4201 agttccatac ctgtagcaag catcactatt tggtgatcaa aactttcacc gtgtaatgga
     4261 atcatactaa gaaatagcaa cgcttctatc aatacaatct tatcaaaatc gtccttaatc
     4321 tcgtccgaaa agaccgactt aaacaattca aataaatcgt aatctcttac acgcgtatta
     4381 attgtataat ctatcactgc acactcggta tcatattcta cagtaaatag atccttgatg
     4441 atataatcat atttaccatc taaactatga aatagttttg ctaattcata tctgctgtcc
     4501 ccataaatat catattttcc aaattttccc ctaggatcaa taaccttaac aaaggaacaa
     4561 ttggaatcta ccatcatatt agcaaaacac aaatctccat gtataataca aaattcattt
     4621 acatcataga gcatacttgg gataagattc tttagaagtt caattacacc ggttaaagaa
     4681 ataaacttac gaccattaat ttgaatttgt ttctcaaaaa aagctgaaaa tcttttatct
     4741 tcagacaatt tttgaaatct ctgcatggtt tttcgcaaat acatatcttc caatgactct
     4801 ctaatctttt catcttttaa ggtgtatcgc ttaaaatcgc tacagataaa ctttatacgg
     4861 ctaaacagat catgccactg gttatatttt aaatcaccat ataagtataa ctcatgaacc
     4921 gtatgatatg cataatattc catatcaaca tagggagcta cgtaagatgt agaataatca
     4981 aaaattctag gtcttacata ttcaatatca gcaggaagtt ttaaatacca ctttatttct
     5041 ccaataaatt tatccttgtc atcgctagtt ttcttcaata tccctcgatc tttatctata
     5101 gagatatgat taaactctcg tgctttaact tccaactttg tattgtaata tttatcgatg
     5161 tgtccaatat caaaccactt ttctgttctt acggccttta gcggacaacg ttcgctgtat
     5221 agctgtaaag cccgataaaa tgagtttatt cccccctgtt tccgactctc aactgcctct
     5281 cttaagcaac tcttcagaag ttttgacgaa gaaaacataa atacgccaat aaataatttt
     5341 tcacgtttat cggatacgta agcttcctct ttatcgtgga tatcagtaat tattccttca
     5401 ttaattttaa agtatgtcca agtactcgac acaaaatctt cagaataata gaatgtatcc
     5461 atttctatat cagacatact ctccataaca attgtatctg cgaagttaat tagaacaggc
     5521 tcatcttcat ctgataaccc aaaatacacg gtttgcccta gatcccctaa ttcaggaagg
     5581 tcacatatat gaattctgga atcatgatag tttttcagtc ttctatgaac cttatccgct
     5641 ttttcataac agataatatc caatgaatcg cagattgcat tatactgatt atacaaataa
     5701 tcaaagacaa tttttttatt aattggatag ataattgctg gtaacattcc tatactctgc
     5761 aattcttttt caacaacttt tgctgctgga attaatacct tcatctaatt actcctttta
     5821 caagtttcac taaaccaatt attgcatagt gcataaatga tttttaacaa attctaacaa
     5881 tgaacagaca ctatagtctt ggccataatt agcaggcaag gtgatgtctt ctgtaatcag
     5941 tactgtctta caaccagcat tttttccagc aattacatca ctttcactat ctccaaccat
     6001 aaatgattga cttaggttta tgttaaaatc ctttgatgct tctaataaca gtccaggttt
     6061 tggcttgcga caattgcaat caatttttaa ttctataacc tctcctgcat atcctttatg
     6121 gggatggtgc ggacagtaat aaataccgtt taaaaatcca ccagcatgcc ctagcattgt
     6181 ttcaagctta ttgtgaatac tattaagctc atcaacagta acttcacctc ttgcaattac
     6241 aggctgattt gttataacaa tacacagaaa acctagagaa ttaataattt taattgcctc
     6301 cgatactcca tcaattaact caaattcttc tgcatttctc aaaaaaccaa cgtatttatt
     6361 aatcgttcca tctctatcta aaaagattgc tttttgtgga ttggatagat ttttaccaac
     6421 aataattccc ttttgaaagt ccttaattac agctctatat cggtccggtg ttcccatatc
     6481 tttaacatac tctggagaat cgtagcaata catacgccct gtgttagcca atggtttcag
     6541 aatcattcta tctaaatcaa ttttgtatgg tagcccccca ccttcaacta ttgatttatt
     6601 tacaatttcc attaatggat tttctctcaa caccttcgga tttataacat gaagacctgc
     6661 atttactcgg tttttataat attcaggtct ttgatcttcc ttcgctaacc attgaagcac
     6721 tttcttattg tcatcggata taattaatcc actatcatac ggatgtgagt taggatgcgt
     6781 aaacaaagta acatctgcgt tattctcaac atgaaatcta atcatctgcc tgaaatcaac
     6841 atcaaatact gcatcagcat tcaaaagtaa aaacggttca tcacccagtt catccaacaa
     6901 aaaatacaat gcacctgcat tgccaagtgg agttttttca ataaaatatt tgattttaat
     6961 tcctaatttt gaaccatctc cgaaatgctc ctctattttt tcatgcaaat aggaaacagt
     7021 caaaataata tcattaaagc cttgatctct aagcgaacac aattctcgtt ctaaaactgg
     7081 aatgccatct ataggaatca ttggcttagg aatatccgga aacaattccg aaattcggct
     7141 tcctcgtccg cccgccataa ttactgtttt cataatatgc ccttccctaa agtacttttt
     7201 actataaaag ttaattactc ttcccaaaca aagtccatat atttttcata ttctgctttg
     7261 tattcgtatt ttccagtgta caaattcaac caatttataa aatcaaaatt atagcagtga
     7321 agtgcatctt ggctatcatc aatataatac gtaccataaa tagtattatt tgaataacga
     7381 cctacatatt tatgccagta caaatcaatt tgatttttgt taatagtaat aacatggttt
     7441 tttacaaact cccaatatgc cctaatagag cactcctcat tgccccccat tcgtgaaata
     7501 tagcttcgaa gaagctgaac ttctggagct aaattatttt cagatatctc ccttcttgag
     7561 actcctctag acacagctcc cttttctctc acatcactag gaatcgagaa gaggtttatc
     7621 atatcatcaa catcaccaaa atacaggaag tctgacaaac aatacgggaa aaacatgtct
     7681 ccatacggca ttgatagtaa cagtaatcgc tgattttgta ttaatttcca atcatcttcg
     7741 ttattaacag gatactgttc aagtaaactg cagaaaaacg ccattgcatt tggatggtat
     7801 attctttgat ctgttctagt tttacaaaca tactttgcac caagctgctt tgctctgact
     7861 attccaggca aagtgtttcc aacttgataa ttaatattta agtgtccagg cttttcaggt
     7921 ttctcactac aaataactat aactccaaga tcctctatcc ttttcaatgc cttaatatct
     7981 tcgtccttcc atgtcgaaag aataattaaa gcatttggat aacatttctt atagtaggcc
     8041 agagtattat aagagaaatc atcctttaaa catagtggcc cctgcattac aattgctaca
     8101 tctttgcaac aattaactaa acccatcact ggaacatcag acatgtcctt tgagcgcaat
     8161 tgaaacgctg cataaacttc agaattttct tctactgttg cacaatcagc agtcaatttc
     8221 caagatacga gtttacttat attatgacca aacatgttcc taaacacata tggtaaattt
     8281 tcgtacttct tcaatatgtt atataaaatc tctttcttat tcatgagatg cactcctatt
     8341 aatatttcct attctatgtt agccacactt ctacattctt gatagatgta ttctataacc
     8401 gctaagcata caggaatagc tggagtaaat atcggataaa accagtctat attaatccct
     8461 gttagcaaga catttaatgt aattccaaat gctaaatatt gatagccagt catacccact
     8521 tttgatgcaa gtaatgctgt tttgaaccct tttataataa acagaatatc aaatataagt
     8581 atacctacac catattgagt aattgtatag aaaaatccaa tatcagatag gtgtcctcta
     8641 actcctcctg gtaatataaa cgtaaattcc tcaccagtaa gaataccagt accgaacaaa
     8701 ggcgattgca aaaatttagg aataaaaaac caaactgaag caaatcgaga ttcagcagat
     8761 cctgcatatt cacctgtact gtttgtgaaa gtttcaacaa atgttgagaa catggtcgaa
     8821 ttaataaata tgactacaag caacccagct aaaacccaca ttgcaatttt tcttttcgaa
     8881 gaacctttct taaaaaggat atagcaacca agtacaataa tttgatagac aaggacagat
     8941 ctagaaccat gaataacagc agaatatgcc agtgcgctag caatcagtaa ataatatttt
     9001 acttttcttc tagctacaac ttgtcgctca atcatataca aagcaatcgg tattattata
     9061 attgtaaaac atggtggatt aattcttaaa aagcctccac gataccaatt ttccggggca
     9121 cactcacgat atatgttttc atagagaagt actcctgaaa atttctgaat aagtgaaata
     9181 gatgttctaa gaatgtatga aagaaatgtt acaccacata tcgtatttag cattgaatcc
     9241 aaattccacg cttggttaat taaagtacag aacaatggat acgccaataa tacatagtat
     9301 aaactcatac tttccctaga tttaacccat attgtcttat ctgagtagat gtaagctgct
     9361 attataacaa cacaaatcag taaagtgcag aaatttaaat atctattttt tctaaatgct
     9421 ggtaatgagg ctattaacaa acatactatt gctagaatga ctgtcacaag tctaacgttc
     9481 atcgtttctc ccaaccagcc gcccaaaggc ttcaatatgc ttgatgagat aatcattaga
     9541 aagaccatta gaaactgtat gattttccat ttactaatct gcatgttaat tattattcct
     9601 ttctaattgt tttactactc attcaaaatt tgtttgtatg cctcgtatgt gagttttgca
     9661 gatgccgccc aggtatactt gcggtttaca agctcatata tatcatcctc tattttgctt
     9721 ttctcagctg ggctaaggtt cacatacttt acaattgtgt ctgctaggct cttagaattc
     9781 aaattttcga aaagtaaccc tatctttcct tcctcggttt cttccataaa agcaggtaca
     9841 ttactaacaa tagttggtaa gcaataagtg tatgccataa gaagcgctcc acttccatag
     9901 atttctttat atggaaatat tgcggcatct gcatttctga acatactgtc catttcttca
     9961 tcagaaattc tctctggctt atatagaaca caatctgaaa cctttaaatc ttcaatcatt
    10021 tttttatagt cagtactatc ctgtttagga tgttgttgac ctgctatggt aaaatgaact
    10081 ttctttctta catccattgg aagttctgtg attgcattaa gcagtacatc aattccctta
    10141 tatggacgaa tttgtccaaa caagataaat tcaaacttat ctttatcata cgctctagat
    10201 atatgtttaa catctccata gatagcatgt ggacaaacat atgactttgc atttaattct
    10261 gggaattcag catataaatg ctgttctgtt actcgattgt gaacaatgaa accatcacaa
    10321 tttgaatata tattaaagtg ctcttggcga tccttttcac gaacctcatg tggtaacaca
    10381 ttatgaactg tcataattaa ttttttatag tgtctcttac ataaaacgta caatccgcct
    10441 tcatatttga gacttttcat caattgcaaa tgaacaatat cataatcacc aaatcttatt
    10501 tccttccaaa ttaagaacaa gcttttcaga aaaacaagtg ccgaaaacac tttatttgta
    10561 cttttatgat acaaaatatg tttgctctta attttaggat ctaaaggagg aacatcacgc
    10621 ttacacagca atgttaaatc aacatattga ttaagttctt tagaaagatc aaacgaatac
    10681 caattctctg gcatttggct ttcacacatc aataccttca taatactcac cttataacca
    10741 atcaacagaa aattctgctt tcagttttcc tttaatttta cgttttgcta taaacatttc
    10801 cagtatctct cgcattttcg tctgatattt tgtcgtttta ccataaagcg agtgattgtc
    10861 ccctgttcct aatacatata ctgctgcttt gaatggaaga ggttttaatg gacgcccttg
    10921 ctcttcacat gctggaacaa cgcccccatg tcgttttcta atgatccatg gattatcatc
    10981 acaatttgct gtcataactt ccggatatgc ctcaggcagg tcttccactg catattttac
    11041 tatacacgca cttcctgatg agaactttgg tagaaccttc atataatcgt ctccaacaaa
    11101 gtacacgtat cccgttttga cataaaatcc attttcctgg ggatgggaat tcacatattc
    11161 cgccaaatga gaacttacaa gatcatctgc gtcaaccatc atagcgaaac cgccgcccaa
    11221 ctctcgcaaa cgcattgcga gagcatgtgt tttataaccc ttatcaatca ttttttcgtc
    11281 ttgatttgtg ggaatagggg catccttttc gctaacttga ataaattcaa ctctgtcatc
    11341 atattcatgc gtgagtttag gaatttcatg gcaagcaaca atgattttga aatcaggatc
    11401 agtctgatta taacacgacc ataatgttcg gttaaataag gtactaacca tctcccaatt
    11461 gtttgctgcc ttcgcactca ttaaaggaat aacaaaatac aacatacaat ctctcctttt
    11521 agtaacgatt caaactacaa taatcattta catcaatatc ttttttcaat actctagccg
    11581 gaacgcctcc taccgaacaa ttaggttcaa catcattaat gaccacagca ttagccccta
    11641 ctattacatt gtcccctatt gtgatattac ctaaaatttt tgcgccagta gcgatatata
    11701 cattgtttcc aattgtaggc ataccaggct tattggatct accaccagtc agtacattcg
    11761 ttccgattat aacgtgatta cctatttttg tatcttttcc aattacacaa cctatgccac
    11821 cgtataagaa cttacaatta tctccaattt ctgtttgata tgaaattgag ctattatgaa
    11881 gtacataaat tagtgccttt acaatcttgg caaaaaactc cattttgtgt aagtaaaacc
    11941 atcgttctac tttgtataat ttatatgcat tcatgtttta tctccccatc tttttagcag
    12001 gtacccccca cacttcgtag ggtggaatag acctcaatac cactgtattt gcagcaacta
    12061 cagcaccttc cccaacgcat aattctgtgt tagatttaca aagaatttta gcacccacac
    12121 ataaaacagc gttctttttt actcgaatga tgatacgttc attactatct gctcaaccac
    12181 acgtcacatt ctgatagact ttaacaccat cttcaaggat tgtgtcagaa tgaatcacag
    12241 tgcctacaga attatgaaca aattcaacag agttccctat ctgtgcacct ttaccaatac
    12301 aacaaccaag aattttggct atttttctcg tgcaattatc aactatgttt aaagcatatc
    12361 gattcctcaa tgccattaat ttcgttactt ccatatcatt tatcaccttc caacatgcta
    12421 agcataattt ctcccgactt tgaccatcta aattctgtag ttacacgctg atatgctgca
    12481 tctatgatat cgttggtaaa tcgtccgtct tttaagaatg tcaaaatttc atcgtcagat
    12541 ttagccaaca ttccatatct attatccaaa ataatattct gtgggccagg tgcattaaca
    12601 gcaataatcc cgaggcgata gtacattgcc tctagcaaaa ccatacccca aatttcagta
    12661 tagtttagat ttacaaatac atccgataag caatataact cccaaatatc tttgttagga
    12721 atacgctcaa ttatttttac tctattctgc agtccaagta aatttatctg ctgcttcgtt
    12781 tgctcgagta aagcaccagt tcctaccatc agcaaataat tatgctcatc aagtttatta
    12841 aataaactaa tcatatctaa cggtctttta tccttttcaa accgtcctac atataaaata
    12901 acacgaacat tgcgaggaat attccatttt tctctgagag tagtaaaatc tattgcttcg
    12961 taattcttat gtaactgttc aaaatccaca caaacaggag caagtttcac tttatttact
    13021 cctaattgta ctaatttttc agaaactcga tcatttttgg caacacaccc atttttctta
    13081 taaattttat aatttcgatg cgccaatatt tcaataattg tctttatata tttattgcca
    13141 ctttgacttc gcgttatccc attataaggt atatatttta ttccattttt tacagtccat
    13201 gagtatacat gaggtactga tagttgaagg tccgcaaatt gtattagaac atccgcattc
    13261 ttatcaaaat tctttgttga taagaatcca tttgatccta cataacgaca cttgatatag
    13321 tgaatcatcg ccgtattgct taattgctct gttccaactt cctcatcact ttttacactt
    13381 ttatatacaa taacttcgtg gcctaattca gctaaccctc gagctaatcc tatttcctga
    13441 gaattatagg accccttctt accaaagtta ttcgtcattg taactactat aagtattttc
    13501 atctattttt attgcccccc tacttagatt caatagtata gtagatatac tttatacctc
    13561 ccaagatata ccgcctccat agtctacgag gttcctttac cagtctaaat aaccactcta
    13621 gactagcttt ttccatccat tcaggagctt tttccaaagt gcccgcaaaa aagttaaagc
    13681 cggcgcctac accgaacatt actgtgttat ggatcttctt ctggtgttcc cacatccaca
    13741 tttcttgctt aggcgcacca ataccaaccc acagaaaatc tggatttaag ttgttgattt
    13801 cctcgcaaat cttgctatcc tcttcttcat ttaacggacg aaatggtggg gaatacattc
    13861 caacaatttt gattcccggg taatctcttt ctaggtttgc acgaagctta tttaacactt
    13921 cgttatcttt tccaccatag aaataatgtg tttttccctg tctaacgcct tcttcaaaaa
    13981 ccattcccat aatatctggt gcagcacatc gttcacaggt aaatcctttg cgccgtccaa
    14041 ttttaacaat aggcatacca tctattgcag ccattgtagc ctggctatac atttcagcaa
    14101 ttttgggatt ttcctttgcc gaaataatgg ccggcactcc cacgagatca acagtcgcac
    14161 ttaccggaga tgttggcatg gaaaaaactt cccttacaaa ctcgttcttt gtagtagcac
    14221 aaacacctac tattccacac acagtgaaat cacgttttct tttatacata ttcttttcca
    14281 tctcagtaca tccttactca tatgttcttc ctccgcatcc tctaattaca cggaggaaga
    14341 acagcttata tacttattaa cccttaatct gcttttcaat ccaattgtag gattcacgaa
    14401 gaccctcttc caaagaaaca gtaggctccc aatccaaaat ctctttcgcc ttagaataat
    14461 ctgcgcaacg agccttatca ccttcaggct tagaagtatc aaagaaaggc ttgatgtctt
    14521 tgccagaaat ttcaatgatc ttatatgcaa tttccttgat ggaagtacag tgagaagggc
    14581 caatctgaat atgaccatga ccccaaccct tatccagggc gagcaccaat gcatttacga
    14641 tatcattgac atgaatgaaa gcacgtccct gctctccgct accccacaca ttaaaaggct
    14701 cttcaggatt attgattgct ttacgaatca gagcaggaat aacctgacta cgttcgccaa
    14761 aatcagtagg tgtgccataa acattatgga gcatcaggat acagcacgga attccggttt
    14821 ctttttccaa ataccccatc tccaactggc ccatcagttt gctccagcca taagcagact
    14881 caggaagagc agggaacaac tcctcttcac ggagaggctc aggattcaaa gtattctgtc
    14941 tggtcagagg gaaggagcat acggtaccaa catagataac acccttgatt ttctccttgc
    15001 cagccttacg gcaacaatca aaaacattag aattgatcag attattgatt cggaacaatt
    15061 cgccctggtt cttaaacaca tagtcaatgc cagccacaac atcagccaga tgaactacat
    15121 actcagtcgt accaataacc tttttagcct gctcataatc agtcagatca gcattgaaga
    15181 aatgagtatc caggtcgatg acaggatgcc catcttcgtc gttcaggtac tccaactttc
    15241 ctctccacag attatcagct acataaacat cccagcagcc ttccttcacc agtctcttaa
    15301 caagattgga gccaatcata ccgcaaccac cggtaaccat aattgtcttt ttcatttaac
    15361 attcctccaa attttattcg tttccaaaga atttatcttc cagcatcaaa caccaacaat
    15421 gatatatcgg caagtgatac tcttgaatca tgtatgtttc aacttcagga gccttaacac
    15481 aaacatctgc taccgtggca agttccccac cctttgcgcc cgtcaagcca ataactttta
    15541 taccgagagc cctagcaaca acagttgcgc tcataatatt cttgctattt ccggacgtcg
    15601 aaataccaag gaatacgtca ccagatctac caaagccaaa cagctgctgt gcgaagacac
    15661 ccaaaccatc gacatcatta atataagcag tagacaatgc ttcgtgtgcg accaaaggaa
    15721 ttgccgttaa accacactcg agatttttgg ctaattccgg acctcttaca gggtcaattg
    15781 caactaactt atcggcaaat tccttactta caggacgtgg cgtcttaaac cgcttcatca
    15841 actcgccagc aatatgttcc gagtcagcgg ctgatcctcc gtttcctgcc acaagaagtt
    15901 taccaccatt caaatagcat tcctccataa ttaggtatcc atcgataatg tcctgtttaa
    15961 tcgtctcaag tgtaggatat cgtttaatca ataagtcaat atgtttatta agtttttccg
    16021 ctaacattgt tactccttat ccattctgtt tttcaatata agtttccggc gtgtagtgaa
    16081 taactctagt tccaccattt tcaaattcaa acggaatata catcaaatca cgcatagccc
    16141 aacgaactgc atcctgtttc tcaggttgta catagaaaac caagaaacct ccaccacctg
    16201 caccgagcaa ctttccgcct aaagcacctg cagccatacc cttttcatat agttcatcaa
    16261 tgcttcctgt actaattgct ccaccagtac cttttttcaa tctccaagta acatcaagct
    16321 gtctaccgaa atcatctaaa tttctgttct tatcagtaag aattgcctca gcttcatcta
    16381 caagctcata catctttttc agtcttactc tcttatcctc tgtgccactg acgttgttag
    16441 ccttttgaac atcagaagaa aatctagtga atccggtaaa gaacatcatc agattgttgt
    16501 taagctgctt tttacgttca ggcgaaataa tgacaggcag cacctcataa ccatccacat
    16561 tgaaattaat tcgattgaac ccaccataag atgcggcaat ctgatcctgc catccaccgg
    16621 cttcattaca cagaactctt tcaagataaa tggcttcatc agcaagtttc ttcttgtcag
    16681 catacttacc ctccagtgca taaaaagcat tcaacatacc aactgcaaaa gaactggatg
    16741 tacccagacc agagcgagca ggtaaatcag cttcgtatgt aagccgaatt tcatgcatat
    16801 cgagcatttt catcgcatta cgaatcgcag gatgctcaat atcttcaatg ctagttactc
    16861 tctcagtacg agaataagat aactcagcgc tgtaatcaaa aaatctaggc agatgtctca
    16921 cattcacata acagtactta tcaaaagtag tagaaagaac tgcaccgcca ttctctttga
    16981 aataatcctc catatccgtt ccaccgccaa aaaaagacat acgaaacggt gtttttgtaa
    17041 taatcataaa tactctctcc taatcttagt ctctctggaa gatatcacgg gtatatactt
    17101 tttccttaat gtcatcaagg caagcatcgt agcgatttgc tataacagaa tcacacattg
    17161 ccttaaactg ttccaaatca ttcacaacct tactgccaaa gaaagtctct ccatctttca
    17221 aggtcggctc ataaatcaca acagttgcac ctttagcttt tacacgcttc ataacgccct
    17281 ggatagaact ctggcggaag ttatcagaat tggatttcat ggtcaaacgg taaacaccaa
    17341 tcacaacagg cttttctttg ccagcatcat actgatttgc ttctgcgtaa ttgtaataac
    17401 cagccatctg aagtacacga tccgcaataa agtccttacg agtacggtta gattcaacga
    17461 ttgcctcgat cagattttca ggaacatctg cgtagttggc cagaagctgc ttggtatcct
    17521 tcggcaggca atagccaccg taaccaaagg aagggttgtt gtaatgagta ccaatacgag
    17581 gatcaaggca aactccatta atgatctgct gagtgttcaa gcctttcatc tctgcataag
    17641 tgtccagctc attgaagtag ctgacacgaa gagccagata tgtattggca aacagcttaa
    17701 cagcttctgc ttcagtaaag cccatgaaca atgtgtccac attctctttg attgcgcctt
    17761 cctgtagcag tgtagcaaaa gtgtgtgcat cctcaaccaa acgctcatca tccatatcgg
    17821 tacccacaat aatacgcgaa ggatacagat tgtcatacag tgccttactt tcacgcagga
    17881 actcagggct gaaaataata ttcttgctac cagtctttac acgaacagaa gcggtgtatc
    17941 caacaggaat ggtggactta ataaccataa tggcatcagg atttacttcc atgaccagcc
    18001 taataacagc ctcaacagcg gatgtgtcaa aatgttgagt gcggctattg tagttagtag
    18061 gagccgcaat aacaacaaaa tccgcagact ggtatgctgc ctttgcatcc aatgttgcgg
    18121 tcagattcag ttctttctca gccaagtact tttcaatata atcatcctgg attggagatt
    18181 tacggttatt aatcagttca accttctctg gaatgatatc caccgctgta accttatggt
    18241 gctgtgccaa cagagtggca atactcaaac caacataacc ggtgccggcg actgcaatgt
    18301 tatactgttt cttcataata tttcctcttt ccaccactgc tgtggtcact actttcttaa
    18361 caaaatgctg tttgtgaaca gtaacctgct atttatataa aacagcccga aagctgtgtt
    18421 cattcatact taaaacagcc agctcctacg ccggcaaatt caatttttca taaatcccct
    18481 acccgtttag ggttatattg caagtttgag tcatttttat tgacctcgtt tggggttata
    18541 atacattttc gcattgaaat gtacctacat tttccactca accagtcacc aaaaagttta
    18601 taaattcact tattaccctc tattcttact ccaaaggtat gtttaacatc gctttattga
    18661 cctattttca ccccaaatgg aagtttgttt ggtacattat tggtctattc ccaccccaaa
    18721 ctgtctattt tgagcgagtt tttgtttttt atcattgcac attttcaagg ctcaaattct
    18781 aagcggattt actggcaggg agacattggt aaatacttga acaatttcac ggctttcatc
    18841 atcacatcct acgataataa ttctaattgg ataaagatta tcattaataa tctactttca
    18901 cgtaaaaatt ctgaactaaa taaaatctat tgataatatt tttttcttcc actttttgta
    18961 tatcctacag gtatagtgga tttaattatc cccaatgcct ctgaagtaac agacatcact
    19021 aattcaataa cacattcact accatagttt gtaggaacaa aaatgacaac aaaatctgct
    19081 tccttatgtg atgtttttcc atctgtccaa attttattac caatgaaatc tagtttaaaa
    19141 tccctcttag aaactagttc actctatatt tttattcagt ttcattagtt ctgttttttt
    19201 gtcttcagtc accatataca tatatatctt aattatctat ccatttcatc ctacgcattc
    19261 ttgcgtaaat acaattcact ctgttgagct gatataaatc attggtggta caaagataaa
    19321 atgataactg tttctatacc tccaaaaatt ccagtaaata tatctataga tagtttcaaa
    19381 aaaaattgtc ttagtttcat aatatttaag atagtggtac atactttata acaacgtact
    19441 tttccaaata ttattttccg ttatgaacat ccaatatatt acaaagttta aaagtttaga
    19501 tgaactataa tcttcatttc tgcacagtgg ataataaatt cttatagata aaaaatagcc
    19561 tcttctaaag tcacaaatac cttactccca cattttaagt aaacactctg cagcattctc
    19621 tttgttataa aatgatagat attcctcaat tttatctctt attatgttat tatcagttga
    19681 taccattcca ttaatgtttc agaataatta caatattttg ggaccggata actccctttt
    19741 gctcgtaacc actcatatcc gttaggattc actaaaagtt taccgtttat ttttcgattc
    19801 tttttttgaa ccgtcccatg aacataccga ttcaacaagc taaattataa aaattggtgt
    19861 gctgtcatta ttttttggaa aatttattaa tggctatcaa tatacttttg tatcatacta
    19921 aatagctcgt cagttcctat atcggatata ccaatattaa agcatttaga tcattatatt
    19981 taagagtggt atcatcccaa aatttcgaat attttctttt atataagaat aatgatactg
    20041 aattgcccca ttcacctttc tttttttaga ttttctacaa gtgattcaaa ccctccataa
    20101 ttacagttat tacttttgaa acgataatat gaacatgtgt aatctttttt attaacaatc
    20161 catcattcta tccctaacta atatgctcca ttgggcttga caataacata aaacgttttt
    20221 aaaatcaacc tcaagtcgta cattaaactt cgatgactaa tatactctaa atccaactca
    20281 accattttat ggaaactaac attatttcta tcactaactt gccacaaacc tgaacaacca
    20341 ggttttacat acaagcgttg aagatcatat ctcgtgtact cagctacttc cctctccaaa
    20401 ggtggccgtg gaccaattag actcatatcg ccttttaaaa cattccatag ctgtggcaat
    20461 tcatcaatgc ttttggcacg gataatttta cctattttag tgacacgggg atcttctttc
    20521 atcttgaaca ttgcaccttc tatttcattt tgatcaagta attcttccaa tttttcttca
    20581 gcatctaaac acatcgaacg gaatttatac attttgaatg tttttccatt tttaccaaca
    20641 cgtgtatggc aaaaaaatat cggacttcct ggctcttctt ttctgattcg ataagctaca
    20701 tagaacatca aaggagaagc taaaatcaaa ccaataatgc ttcctacaat atcaatcatt
    20761 cttttaaaaa ataaatagat atatcgtttt tcaacttttt ctttatccaa ccaaacttga
    20821 ttaggatgta cttcactaat acgagataat aaatcttcac tttccatact ttccctctct
    20881 cctcatttcc tttttatcta cgaataaaga actaaaataa accaaacttc ttctttttta
    20941 cctcttcata gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt
    21001 tcatctgtac tactttttcc ttaccaaagt ccttagcaat ctgctcatag cactctttta
    21061 agtaaaaggt acgcttagag accccatggg catcagaagc agccatctgc acaagattat
    21121 gtttgaccat cattttggct gttttctgga tgtcttttcc aaatacaccg acataacttg
    21181 gtgcggtgag ttgggccaag catcccatat ctaggaatgg cagcatatga ttcgggtctt
    21241 tacgaaaatg cgcgttgcgt tctggatgga cgatcactgg tgtctttcct agttgtaaca
    21301 actcaaaaaa gagctgttct gcatataacg gcacttccag tgtcggaaat tcgattagaa
    21361 gatatgtatc atctaaatct gtaaataaaa tttcatctcg gtcgatgtct tcgatcagtg
    21421 ttccggtaat acgtacttct tgtccttcca ataacgtcaa aggcaattgt cttttctcta
    21481 attctgcttg taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc
    21541 cattattatg atggggtgtg cataaaatat gtgtgatccc ttgttgaatc gctttttcag
    21601 ccatggcgat actggcatct atgttttctg ctccgtcatc gattcctggc aggatatggc
    21661 aatgtagatc gatcatttct cttgtctcct ctctttttat ttcttaattc ccgtagtaat
    21721 agccagcatc tttgctgtgt tctgccccat tgtatacaac accaaggact cgcgcttgta
    21781 ccatatccag caattctttt gctttagtca atgattcttt ccgtgacata ttttcacgta
    21841 cgaccaataa ggtgccatcc gttttggaag acatgatctg tgcatctgtt acggcaacta
    21901 ctggcggcat gtcgaagatc actacatcaa atagttgtct tgcttctgct aaaatctgat
    21961 ccattcttgg cgaacttagt agttctgatg gatttggtgg tttaggtcca cttggcagaa
    22021 tcgacaaatt ctcgactggt gttcgttgga tctcatctgc tacacttcct gatgaactaa
    22081 gaacggtact taatccgctt gcgttgttca acttgaacgt tttatagatg acgggcttac
    22141 gtaagtctgc atcgactagc agcacccgtt gaccagattt ggcaaaaaca acggcaatgt
    22201 ttgctgcagt ggtcgatttc ccttctccag gtcctgatga agtcacaaca atcgttttaa
    22261 tttgctgacc agctgcggag gcaaactgga tattcgtccg aatcgtacga tattgttcag
    22321 cgattggtga agaggggttt gtgagtgtga ccaaactgac tgcatgagtt tgggctgctt
    22381 tttgtttctg tgttcgtgcc atttttcttt cctcctagac tcttgagcgg cttctgcgtg
    22441 atggcgctgt tttatcgttt gtagcttttg gttgtatcgg agctggtcct tttttacgga
    22501 taccagcatt caattctttc gctgacattt ctggtacagt ccctaagatc gggaagccca
    22561 atgtatccgt cacatatttt tcatctttta ctgtccggtc gagtaattca aataagaaag
    22621 ctagacctac gcctaccatc attcctaaca ctaagccaat cactagattc aatttattat
    22681 ttggcgaaac aggtgtcgta ttggcaactg cacctgagat gatcgagatt ttatcgacat
    22741 tcatcacgtc tttggcgttc tcttggaata cttgtgacgt tgtattagcg atttgttgag
    22801 ccgtcactgc atttgtgctt gttgcttgga tcgagaacat ttgtgaattt tgtgactgat
    22861 tgacggagat ggcatctttg atttgtccag cagtcatttt tacattgtct tctgtttcta
    22921 aacgatcttt gacttcattt agtactagat cactgacgat catatcctta tacgtattga
    22981 tcatttgcag gttcgtattg acatcattga catttgcagt atctgattgc ggcagtgtca
    23041 cgatcaattg ggcttgtgag ctgtattttg gcgtcaagat gaaaaacgtc acgatgcctg
    23101 agatggccaa gccagcaaac attgagatga ggattgttat cacgtgtttg cgtaatgttt
    23161 caaaaatttc tttcaagctg attgtctctt ccattttttc tccactttcc tatttattct
    23221 ctagattcat ttgatctttt aattcttttt tcacacgatc aagttcttga tcgctgactt
    23281 tttggtatga gatattgtct tgcatgaagc cttctccttg cagctgatct tgcttgatcg
    23341 taccaaatgc atcccgataa tctaaagcaa tctttttcat ttcatcaaag ctcatgtctg
    23401 ttttcatatt cgactctaga gcattcaaaa cggattgata gttgcttaca ccgttcagac
    23461 tcaacacttt tttcgctaca ccttctacga tctttctttg acgttcttgt ctgccgtagt
    23521 caccatttgg atcttcataa cgcatacgag aataagacaa tgcctgatcc ccgttcaatg
    23581 tgattttacc gatcgtaaaa tcatagccat cttgtgagaa ggtgaggtca ttattgactt
    23641 cgataccacc aactgcatca acgagttctt ttagaccttt catattgatt gaaacatagt
    23701 gatcgattgg gatgtctaca tatttttgta cggtatccat cgccatggca gctccgccga
    23761 atgcgtaagc gtggttgatc ttgtcttttg tgtcatgtcc aacgatgtcg acatacgtat
    23821 cacgaggaat gctgacaatc gttgtctgtt tgtcttcagg actgactgtg gcaaccatca
    23881 tcgtatctga tcttccttga tcgacccgac ctaaatctcc cgtatcaatc cccatcaata
    23941 gaacagagaa agattcttgt ttgtccagat caactggttt tgttcgttct ccttgggttc
    24001 gttccactga ttcgtaagtt ttttcaatag aatgtgagag atctagatat aattttgctc
    24061 ctactcctac gattgctaat actaatacga caagaattgc taaaataatt agaaatatct
    24121 ttttccctct tgatcttctt cttcgttttg ccatagtttc ctccgtttgc tagccttgct
    24181 tgaattctcg cttattaata gctcgtattg ctatagccca tttgctgagc gactgtttct
    24241 gcttttgacg cgtatgcggc tcttattttt tcattccgga tctgttcgat gagactgagt
    24301 gcggtcaaat attgatcgta agtagcagta gctgttactt gaccgtcttt cagcatcgta
    24361 tcgaatagct gatctagttg cgtgacttgc gcgatctgag tatcagcgaa tcctagatat
    24421 tgcataacaa ccgttttcca aggactatct ttaaaaaagc tcatattttc acgtacacga
    24481 gcgacatctg cacttgtcac cttttctttg atgacgacat cgtctacagc ttgctgccag
    24541 tttgatacat ttttagtaaa taaatcgttg acagctgtct ggatcttcag ttttgattct
    24601 gcatcctcta actgcgttaa gactgctttc ttttcttctt ggatcgcagc agcttcttta
    24661 ggtaattctg attccttgat gtcataatca tctgccgaaa gtttgataga agatagttta
    24721 tgtgacaaat ttgaaactgt ttcttctgtt atttcaggat ttaggaaaat tttttctttt
    24781 gtactgtaca gcttatctac ttcttttgat aaagaggtca cggtgtcttt ttgattggtg
    24841 atggcagatt ctgcgtaatt gatccgttga tgatgttgcc gctgattatt gaaatggtat
    24901 ccaaacaagc aaatcacaat agcgcctgtg cctaccgcca cagtagccaa taacttgacg
    24961 aacggctttt ccatagattc actcctaaat attgatgata gataaataaa gatgtgattc
    25021 attcccatca gaatgagcgc tttttatttt aaaagcataa ttaaactaat atattcatag
    25081 aaatatttat aaacaggttt tccctatata atcataccac aaaaagtttt cttgactagg
    25141 gaaattccta atttaaaagt aaataaaaca gtaacaagat catgattaat cgttttcatt
    25201 tttatttcct ctcttttcat gagcattttg aaaattcgaa caaagaataa aataacaaaa
    25261 attattaaaa tagaattaat aacagctatt tatatttata acaaaaaaac agagacacag
    25321 cacgtttcgt gcatgctctc tgtttttcaa acaaaagact attttgtgat gatttgatcc
    25381 aagcttgcta atgacaaagc catggcagct atttgactaa gttgtgttag tcggttctta
    25441 cgtactgctg gttcatcagc catgaccatc gtttgatcaa aataattttc gatcagtgga
    25501 cgaagagcga caagctggtc gtagttttcg tggatcgttt ggtcagcaaa acttgctttc
    25561 attgcttcta ctgctttgtg taattctttc tctgcgtcgt tttcgaacag ctcaggatct
    25621 acttctgatt gtttttcaag ctgcgctttt ttcgctaagt tcacgacacg tgtcaaagct
    25681 tccattgaag gtttgaagtc ttcatctgca agatgttgtt tgaacaattg tgctgctgca
    25741 aatacttttg tcagatcttt ttgttccgca ttcaaaacag catcgatgac atcatgacga
    25801 atattcttcg ttgtcaataa ttggcgcaga cggcctttga taaagtcgat cacttgttgt
    25861 tgcccttctg ataaaccaat gccgaaacga tccgtatctt tactgataac atcgctaatc
    25921 gtttcttgca gaacagacaa aggaaaggcc cattttttcg attcgatgat ccgaacgaca
    25981 ccgtatgctt ggcgacgtaa ggcataagga tcgtttgaac cgcttgggat catcccaaca
    26041 gcaaagaaag aaaagatgct atctaattta tctgcaatcg ctaaaacaga acctactgta
    26101 gactgaggta gctctccttc actggatata ggcatgtaat gctcacgaat cgctgtcgct
    26161 acagcaggtt tctcgccttt cagcagagca tatttttcgc ccatgatccc ttgcagttca
    26221 ggaaattccc ctaccatgtt ggttactaga tcaaatttat agatttcagc agctcgttgc
    26281 agatccatca attcttcctc agatagtcct acttgttcgc caatgatacg ggcaatgact
    26341 tgtacccgtt gcattttctc atagatacta ccgatttttt catggaaagt aacagttttt
    26401 agtttttcaa cgtattggtc gattgaagct ttcttgtctt cattataaaa gaattccgca
    26461 tcttctaaac gagccgtcaa tactttttga ttgcctcgaa ccacattttc caattttacc
    26521 cgatcaccat tacgagcaga aataaaatga ggaagcagca taccttgatc attccgtacc
    26581 tcgaaataac gttgatgttc tttcatagaa gtgactagta cttcttcagg aacagaaaga
    26641 tatttttctt cgaagtcgcc agaaaagaca gttggatatt cgactaaatt gttgacttct
    26701 tctagtaaat cttcgtctag atcaataacc caatgatttt tttcggctaa ttcattggct
    26761 tgtgtaacga tcatttcttg tcttttttgc ggagacgcaa tgacgaattg ttcattcaat
    26821 ttttcttcat attcttttgc atgcgcaaat gtcacatctt cgcctaagaa acgatgacct
    26881 cgagaggctc tgcctgtttt gacatccaag atttcgaatg ggattacttc gtcatctaac
    26941 aatgccacga tccagtgaat agggcggata tattcaaaat cgtattctgc ccaatgcatc
    27001 gttacaggga aagtcaggct tttaatgaca tctgctaaac ctgtcaatac ttctttggat
    27061 tccttaccat gagtgtattt cgttacatag acatattcca caccttttaa ttctctaaaa
    27121 gtgatagcgt ctgtcgtcag accttgtccg cggacaaatc cttccgctgc tttcgtccag
    27181 tttccatctg cgtccaaagc aatttttttg gctggtcctt tgacttcttc ttcactgtcc
    27241 gcttgtcgtt ctggaatgtt tgttactttg attgctaaac ggcgcggtgt ggaaaatgtt
    27301 tcgatcgtat cataagtcaa ttggttttca tctaaaaatt ttgctgtttt ttcttctaat
    27361 tgtttcatgc ttggtgtgac aacatgagca ggcatttctt ccagcccgat ttcaagtaat
    27421 aagtcttttg ccatcttatt cagcctcctt cacgttttct ggatttgctg tgtttttatt
    27481 caacaaaggg aatcctaatt tttcgcgttc tgccacaaag attttggcta cagcacgagc
    27541 catgttgcgg atgcgagaaa gataaccggc acgctctgtt acggatactg caccgcgggc
    27601 gtctaataag ttgaatgtat ggctacattt caagatataa tcatacgccg gatgaacaag
    27661 attttcatcg atacagcgtt tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa
    27721 gtcttggtcg cttacttcaa aagaatattt agaatgttca tattctggtt gtttgaagat
    27781 ctcgccatat ttcacgccat cagcccattc taaatcatag acactttcaa cttcttggat
    27841 ataagaagca agacgttcta atccataagt gatctcagaa gttactggtt tacaaggcag
    27901 tccaccaact tgttggaagt acgtgaattg tgtgatttcc attccgtcaa gccatacttc
    27961 ccaacccaca ccggcacagc ccatggatgg gttctcccag ttgtcttcaa caaaacggat
    28021 gtcgtgttct agtggatcga ttcctaaaag gcgcaagctt tctaaataaa gctcttggat
    28081 attctcaggt gaaggtttca tcacgacttg gaattgatga tgctgataca aacggtttgg
    28141 gttttcgcca taacgtccat cagctggtcg gcgagatggc tctacgtaag cagcattcca
    28201 tggttctggt ccgattgccc gtaaaaaggt atatgggctc atcgtacctg ctcctttttc
    28261 tgtgtcatac gcttgcatca gcatgcagcc gtttgatgac caaaattttt gtaatgttaa
    28321 aatcatatct tggacggtca attttttact catctgtttt gcccctttca attttaaagc
    28381 gttgctgtca aataagaata caggaaagaa aacgacaaaa aatccctatg tctgattaca
    28441 gacataggga cgaataattc gcggttccac cctacttccg aataaagatt cggcagcttc
    28501 atttatcgta ctcgcaagtg cctcttcaaa aatcgtttgg gtccggctcc cactctcccg
    28561 aactcgctaa accacgtgtt ttttactgat cttggtcaat gtacgtattc attttgcagt
    28621 tttcttgttt ctataataga tcctctcagt gaacgatcta tttgatctac ggttaataat
    28681 agacggaact ccctgtgttt gtcaaatggt tttgattttt tgttgtatgt ttcatttact
    28741 attcttcttt tttaggtaga tctttttcag acatgtcttt ctctgacgtc tttaatacgt
    28801 gtgcccaaga cttcatttga tcaatgaact ttttgctttt caaatggata ccgacatatt
    28861 catcatacag ctggtcgatg agttcacgga ttgcttgttt ggtttcttct ttcagatgga
    28921 ttccactgat tttatcataa gaaatagctg aaaacatccg aacgaaataa acagctcgag
    28981 gatctgcatg ataacggtga tcatccatcg accagtgtct ttcgcatatc acaccaccat
    29041 atttggaaga atagtcaaat tttccttttg tttccccaca tacgacgcag tgtgtccaga
    29101 ttggtgcaat tccgaagcgt tgcagtattt ggacttcaaa aatattcgtg atgatttctg
    29161 catcatctcc ttggtccatc agttgcagtg cttgttgcgt aaactggaac aaatgcgggt
    29221 cgtactgatg atcttcgatt gccgcatcta ctagattcaa taaatatgtg ccatagccgc
    29281 tcaaaaagat gtcttcttgg atgtgtcgaa acgcgtggac atctttgaca ctgcttaaaa
    29341 atgacaaacc ttcacttcga aaattcccga tataaactgc ttcagtaaaa gggagcaaag
    29401 ccggagctaa gggctgattt tgccgatgga tccctttgat ataaaacatc attttgccag
    29461 aagattccgt aaagattttg actaatttat ctttttcttt gtaattacgg ctagataaaa
    29521 tcaagccttt tgattctgca agctggctca tattctccct cctaaaaaat aaatctggaa
    29581 aagcagattc tgccgatcca gatcatttat gttgcgatct tccgcagctt ttctcaacac
    29641 gcggattttt atccagttta tttctatacc taacttacaa gaagctcaga atatcaatat
    29701 tcgtcttttc ggtagccgaa gtcttgcaga tagacttttt tgtctcgcca gtctttttga
    29761 actttgaccc aaagttctag aaagactttg tctcctaaaa gattttcgat atcttttctc
    29821 gctttcgttc ctacttgctt cagcattttt ccgcctttgc cgataatgat ccctttttgg
    29881 ctatctcttt cgacaataat cgtagcctgg atatggattt tatcattctc gtttcgcttc
    29941 atcgaatcaa caacgactgc gacagaatga ggcacttcgt ctcgtgttaa aaacaagact
    30001 ttctcacgga tcaattcaga aacgatgaag tattcaggat gatcagtcac ttgatcatct
    30061 ggaaaatatt gtgggccctc tggcatttca ctgactaata catccatcaa acgttcgacg
    30121 ttgtttcctt ctgtagcaga aattggaatc acttgtgcaa acggcatctg cgttgaataa
    30181 tcttcgatga ttcccaacaa ctcgtctgga tggattttat cgattttatt gataatcaga
    30241 taaacaggag aatgcacgtt ttttagacgt tcaataataa aatcgtctcc ccgaccgcgt
    30301 ttttgatcag cgctgatcat aaataagacc gcgtccactt ctttcaacgc actgtaagct
    30361 gcttctacca taaaatctcc taaacgatgc tttggtttat ggattcctgg tgtgtcaata
    30421 aaaatcaact gagcttctgg tgtagtatat actccttgga ttttatttct agttgtctgc
    30481 gccttatcac tcatgatggc aattttttga cccacgattc gattcaataa tgtggatttt
    30541 cctacattcg ggcggccgac gattgcgaca aaccctgatt tatgttctgg catatacgtt
    30601 ctccttttta attaaacaac aaatgatata ttttagggac aaataaaatc aacccaacga
    30661 tgacggaaaa acaagcggtc actaaaactg ctccagctgc catatctttg atttttttcc
    30721 caatcggatg aaaatgaaaa tccgtaaaca tgtccacgac attttcaaaa acagtattga
    30781 tgatctctac tatccatacg agaaaaacag ctaaaagcag ccataaccat tctatccgat
    30841 caagctggaa aatcacgccc ataaacaaag cgaggattcc gaacgcaaca tgtttcctca
    30901 tgttgcgttc ttcctcaaaa acggttttga ctccttggac ggcaaattcc acggacatca
    30961 ggaaatgttt gtttttctct acgtttttat cttttaagtc cataggcatc taagatctct
    31021 ttctgtaaac caaacatttc tttctcatcc tctggtgtca tatggtcata cccgttgata
    31081 tgcaagaatc catgaaccgc taaaaagcca agttcccgat catacgaatg gccgtaagct
    31141 tctgcttgct ctgcagcacg ttcagtagag atcatgatgt ctcccagtac acgaggcaat
    31201 ggattctctc catcttcaaa aatcactggg atttcgtctt cgccctcttc ttccaaggca
    31261 aaactgatga cgtctgtcgg tgcatctttt ccacggtaat cacgattgat tacttggatc
    31321 gctgcattgt ccatgaaagt aacagacatt tctgtttctt ctggcaactc taaatatgat
    31381 gctgcaaatt gcagcaagtc gtcgatttct ttcattttct cttctgagac ttggtttgtt
    31441 tcatccatga aagtaatatc cattatacat cgcttctttc tattcttctt gttcttcttt
    31501 tatcttctca acttccgatt tcattttagg atatttgatc cgagaatgga aggtactgct
    31561 taaaccgctg atcaatgatt tttctacttt acggatttct tttaacgtca atccactgtc
    31621 gtccaattgt ccatcggaaa tacgctcttc aataagatta tggacaaaac tttcgatttt
    31681 ttcgctcgtt ggatggtcca ttgctcgtac tgccgcttca caactgtcag ctatattgac
    31741 gattcctgct tcacggcttt gaggttttgg tccaggataa cggaattgct cttccgtgac
    31801 ttccgggttg cgttcctttg ccttaacgta gaaataacgc atcagcgtgg ttccatgatg
    31861 ctgtctgcaa atatcgatca ccatttgcgg catattataa tcttccaata ttttggcacc
    31921 atctgtcaca tgtccaaaga taatatgttt actgtcttct ggcaataaga aattgtgcgg
    31981 attttccgct cctgaaggca agttctcaac gaaaaagctg gcgtgtttga tcttgccgat
    32041 atcatgataa tagcaagcta ctcgagttag taaagaacgt ccaccgattt ctgctacagc
    32101 attagcactt agattggcta ccatcatgct atggtgatac gtgcctggtg cttcttccag
    32161 caactgtttc aataaaggat gattaggatt gctgagttca tttaatacga tcacactatc
    32221 atcattgacc atcaattcaa tataggggtg cagacctatc gtcagcaaga atgagaacag
    32281 tgcacctgtg aatccgcata ctagcgttaa ccaagtcgtt gcatccccaa agctcattcc
    32341 ttggtagata atcaaaatga catccatcat cacaggaaaa ataatgaccc acatagcagc
    32401 ggataaccct tgttctgaga tccgtttgcg tctgacgatc gttgccatga gaccagaaaa
    32461 tacataggac atcaaaataa ctgtcagaaa gttcgtgcca atcgaatcat aaaaaatgaa
    32521 aagtgcggat actgcttgaa aaataccagc catgatccct gctcttcgat tcaagaaaaa
    32581 gcttaaaaca agtggagcaa aagccgcggg gtaaaacagc ggaatataag cagcttgttc
    32641 tgtttggaag agttggaaaa atttcattag tacgacgctt actgacattg ccgtcacgta
    32701 gaaaagtacg tattttgttc tttctcctgc attttggaat tgaagtgaat tataaatcag
    32761 tacaccgatt tgaagcaaaa cagctaaaac catggcaatg agtgggaaaa tagaagtcgt
    32821 ttgattcgtc aatcctagta attccaattt tttcatcgct gaagcatcaa tttgatttcc
    32881 ttcgcgaaca ataatttctc cttggaagat catcactggt tgtacagctt ctcgtgcaga
    32941 ttgttttaat tcttctgtct ttttctcatt caatacatca ttaactacaa tgccttgatc
    33001 cactaagtag cgaatcattt gttgctgctc tgttgtgaca ttcaaatatt gaatctgatc
    33061 ttctgcttct tgtttaaaag cttccaattc gctttcacga acttgtttac tcatctgttc
    33121 gtcaatgagc ttcaaacttt catccctaac cgtgtgaatt tccgtttcag tcatttcaaa
    33181 tatcgtcgaa taaaaattgt tcggcagttt ttggtaaaac gcaacgtttt ctgcattcac
    33241 gttttcaaaa tttttcttca gtgtagcaat ccgctcttct gtagtaggtt tcgggatatt
    33301 ttcatcttcc ttcgccttat ctaccttgtc attataagat ttgttgatgg tatcattcgt
    33361 cttatcgatc aattcgaata attgcttgat ccgattgttc tggtcatctg ccagatcttt
    33421 ttgataagta tattctggag tcactgcttc tgctgccagt tttcttcttt gttcggtttc
    33481 ttccgtgttc tcaatcgttt tattcgcacg gatactctct tctgctactt ggccttctct
    33541 gaaatcattg gccttttgtt tgacactact aaatgtaacg ccgcagacaa tgataaaaaa
    33601 caagaacaga aggaaaggca atgctgcctt tccgagtttt ttttgtagtt tctgcagtgt
    33661 tttattcaac atgtgcttat cctcctaagc aaagcttatt cttgatgaag atccgccttt
    33721 tcataagctt tgatgatttc ggcaactaca gggtgccgaa caacgtcact tgcttcaaaa
    33781 ttaacaaaat cgattttttt gatttgcttt aatgttcgtt ctgcatgaac aagaccactt
    33841 gtcgtcccac gaggcaagtc tatctgactt gtatccccat tgacaatcat ttttgattga
    33901 taaccgagac gggtcaagaa cattttcatc tgagcgactg tcgtgttttg tgcttcgtcc
    33961 aagataacga atgcatcatc caatgtccgc ccccgcatgt aagctaaagg tgcgatttcg
    34021 atcacgcctc gttccatcaa tcggttcgta tgatccaatc caaaaatttg gtataaagca
    34081 tcataaacag gccgcagata aggatccact ttttctttca gatccccggg tagaaagcct
    34141 aggttttccc ctgcctccac agcgggccgc gtcaaaatga ttttttgcac ttcgcctttt
    34201 tttagggcag caattgctaa tactacggca agaaacgttt tccctgttcc ggctggccct
    34261 acaccaaata cgatgtcatg tttggctacc gattcaacgt atttcttttg accgctgttt
    34321 tttacccgta taggttttcc attacggtct ttgacgatct cttcctcata catctcaaca
    34381 aaataatcta atgtaccttt ttgccccatc ttcaatgccg tcacaacatc tggcgtactt
    34441 acgtggattc ctcgtttgat caattcctgt aatgtccgaa tgactgaggc agccaaggaa
    34501 atctgggatt gctcaccaat gatctgaatg atttctccac gtgtatggat ggttgtttcc
    34561 gttgtttcct cgatcagttt tatatgcttg tcgtgtgcac ctaaaagcat gctgacatca
    34621 tcagcagctg tcaatctaat ctctaaagaa ctagactctt ccgtcaaaaa tagacatccc
    34681 ctttttttcg attcattctt tcctatttta ccatactcag aagaaactat atagcaaata
    34741 agaaaaggtt gtaaaagagt cgtttaacca tacgtaccaa gaaacgttaa aaaatagccg
    34801 tttccattcg ctaaaggtct cgttttgata aaaagaagct gagaatgtaa gttatatgaa
    34861 agtggagaac aaaatattcc gtttcattca gcaggtattc tctaggtatt tttcttgttt
    34921 caaaaaaaga aaacaaaata gttaaaatat tcttgcattt caaaaaaaac aggtgtatta
    34981 ttacgtcaac aaataaacat acagcaaagc gtcgaggaaa acagtaggct attcaacgat
    35041 ttattcccag tgagtcatgt aagtgagaaa tgacaataaa tcgaatagac gaacatcatt
    35101 tccgagtcaa tgtcgaaaac gtagatcatt gtggctgcct ccattatcag gctagcggat
    35161 aactttatca aaaagcgtcc gtgaatgaag aagctttttt aagcgaaaaa aggtggtacc
    35221 gttctagaat ctagagccct tttcccaagt ggaaaagggc tttttttata ttttaaggtg
    35281 gtggttttca tggaatctga tattagtggc attactaatt gctgcaacgt ttatatcgtc
    35341 aatcaaaatg ataattattg gaggaaaaat ttatggaaga aacaaaaact tattcatgga
    35401 aacaactatt gatggtcagt tcacttatct tcgggatgtt cttcgggtca ggtaatctaa
    35461 tctttcctgt ccacttaggt caaatggctg gcgcaaactg ggtcagtgct ggcgtaggat
    35521 ttgccatctc gggcgctctt ttcccattac tagctatctt agctgtagta gtgacaaaaa
    35581 gtgatggtct gtatgactta gctaaacctg tcggaaaatg gtatgctgcc ttgttcttaa
    35641 tccttgttca tttgacgatc ggaccatttt tcggtacacc acggacagct gctactgctt
    35701 ttgaaatggc tgctaaacca tttttgcctg aaaaatataa ttcattaggt atgtttttat
    35761 tctctgctct tttcttttta cttgcttatt tccttactgt ccatcccaca cggttggtca
    35821 aatacgtcgg aaagtatcta aactccttgt ttcttgcatt gttagcaatc atttttgtcg
    35881 tttctttatt ccacccaatg ggaaatctaa atcaatctgc tgcagatact taccaaacaa
    35941 acgctttaac aaatggtgtc ctagaaggtt ataacacggt tgatgcagta gccttgcttg
    36001 ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg tttcaaagat aaaaaagtca
    36061 cagaattaac agcaaaagct ggtagcctga gcgttgcgct agaagtcatg atctattttg
    36121 gtcttgttct tctcggtgcg atgagtttga ataagatgtc tttatcagaa aatggcggaa
    36181 ctgcactttc tcagatcact aatttttatt taggtaactt cggcgctagc ttcttaggag
    36241 tgatggtcac attaggtgtc ttcactaccg ctatgggact cgttgtttct tttgcgcaag
    36301 atttccataa actgttccct aaagtcagtt atatgacatg gctgcggtta acgactttcg
    36361 tctcttttgt cgttgcaaat gctggtttag acaatatcat ccaatggtct ttaccagtat
    36421 tgatgctttt gtatccattg tcgcttgcgt tgatcttgct ttccttaaca gcaaaatttt
    36481 tccaaaagac accatttgtc tatcaagtaa cgatgttgtt tgctgctgtt cctgccgtat
    36541 tggatatgct ggcaaattcg cctgctttag tgagtcaaca aagagttgta gcaagcatgc
    36601 tcgaatttta tcatcatcac gttccttttg ctgcattagg acttggctgg atggtcccaa
    36661 cgttacttgg ttacgctggc agcctactgt tttattacgc ctatcgccta tcagggtata
    36721 aacaagaagc aaatgaacta ccagaagaat aaccaaatca aacacaattt aacataagaa
    36781 atattaaaca ggaaaaaacc agctagatga aagaatccta ttctttcgtc tagctatttt
    36841 tttgttctct tttttacgcg cacaaaaaaa ctgcggacaa tgattgtccg cagtttaaat
    36901 gataaaatta agattgtaat agttctttca caatggcatt tacttggttt ccatctgctt
    36961 ttcctttgac tttaggcatg atcgcaccca tgactttgcc aaattctttc attgatgaag
    37021 caccagtttg tgtgattgct tcttgaacaa gttgtcgaat ttcttcgtcg gaaagttgtt
    37081 ccggcatgta tttttcgact atcacaattt cactttttac tttttcagct aaatcgtcac
    37141 gtcctgcttc ttcaaactca tgcaaagaat cacgtcgctg tttcatttcg cgagacaaca
    37201 ccgttaattc ttcttcttct gtcaagtcgt gaccttcttt aatctgctcg ttttgtatag
    37261 atgacttgat cattcggatg acttgtaaag attccttatc tttcgctttc atcgctgttt
    37321 tcatgtcatc gtttaatcta cttagtagtg acacactacc aactccaatt catcacagaa
    37381 ctagaatttt ttgcgttttc tagctgcttc agattttttc ttgcgtctta cacttggttt
    37441 ttcgtagaat tcacgtttac gagattcttg taaagtaccc gcttttgaca cggaacgttt
    37501 gaagcgacga agagcatcgt caagtgattc gtttttgcga acgactgttt ttgacatgtt
    37561 aattccctcc ctccgagctt aaaaagtaac cgtaattgtt attgaaatat atctcaaaaa
    37621 acaagactgt cctgtaaata ttatatctaa tgctgttttg accgtcaagg aaatcttgct
    37681 tttttttaaa attatcaaat gttattttat ttaaatcctt attgacaatt ttcacatctt
    37741 ccgaaaatct cgaatctatg cccttcgatc gtacatccac cgagctgttc ttcgaaataa
    37801 ttcattggac acatatggat ttctttcgtt gttccgcaca ccgtacagat aaagtgatgg
    37861 tgatggccga tttccccttg acagcaatga aaacgaaact tcatctctcc atttaaatcg
    37921 gtttcttcca gtaaatcgat ttctgcaaaa tcatggagat ttcgataaat cgtatcgtaa
    37981 cttactcctt tgaattcctg attcatatag tcaaaaactt ctttagcgga tacgtagcga
    38041 ttgcgcttca ctaaataagt taacaatgct tctctttttt tagtatattt aaaaccgtta
    38101 tttttcaatg tttctagtga ttgttcaatc aatgtctgtt ttttcatgac ttattcctcc
    38161 aaatcaaaat gattacgaag tacacattct agagtatggt ataataaaca taaaaaaaat
    38221 gcaagtgagg ttttatccat gtcttccgat tctacagaaa tcgttacttt ttttgtcatc
    38281 tctgactctg ctggagaaac tgcgacaaaa ttagcgcaag ccactatggc ccaatatcct
    38341 accgttgagt tcaatttatt ccgcagaaca tttgtgacag atgagaaaac attgatgcag
    38401 gcactgcaag atgcactaaa agaaaaagcc cttgtcctgc acacattgat caatcaagaa
    38461 ttgatcgaga tgacgcgttc tttttgtgaa gaacatcaat tatttagttt tgatgtgatg
    38521 actccgccga tatcagaaat cgagcgctta actggtatca agcccattcg gcaacctggc
    38581 gcccttcatt tattgaatga gaactatttc aaacggatca aagcaatgga atttgctgta
    38641 aaatacgatg acgggaaaga tcctcgtggg tttctagaag cagatgtcgt tttgctaggc
    38701 gtatccagaa cttccaaaac gcctttgagc ttgtttttag ctaacaaaaa tttaaaggtt
    38761 gccaatctac ctttgatccc acaagcacat attcccaaac agctttggga gatcgatcct
    38821 aaaaaaatcg tgggactgac gaataaccca gatattttaa acaatatccg taaagaacgg
    38881 atgcgctctt acggattaaa tcctgatact gcttattccg atatcgaaaa aatacgagct
    38941 gaactcgatt ttgcgaatga tctttatgaa aaattgggct gcgtagtaat caatgtcgct
    39001 tctttatcta tcgaagaaac agcttcactt attttgaatg ctttagacct agaagatcat
    39061 agttattatg gaactgaaac caccgaagaa acagactaac agtttttctt gtctttttct
    39121 taaaaaaact ggactgtgtc agcgaagaag attcgttgat acagtccagt ttgtctctat
    39181 ttgcacctat cgttattgat gttccacatg tttgagcgtc tggttcaaaa tatccagtac
    39241 gtgagaatca tcaagactat acaaaatcgc ttttccctca cgatgggact tgacgacatg
    39301 gttttctctt aataaacgca gttgatgcga tacagcagat tgttccattt ctactgcttg
    39361 ggtgattgct gtcacatttt gttccccgtc tttcagatac agcagaattt tgagacgagt
    39421 ggggtcactc aacattttga atagttggct gactttctct acttttgttt tttgcgtgtc
    39481 tggcaatcca ttcacctcca acttgaaaaa agactgactt ctaaagttta ccactttttc
    39541 catcagtctc aagttttttt attcttctgt catttttttg ataatcgctt cataagcggc
    39601 tactttttca gctgcgtctt ctgaagagtt tccttttaca ccgatataaa atttgatttt
    39661 cggctcagtt cctgaaggac ggatagcgat ccagccattt tcttccagcg tatacttcaa
    39721 tacgtcagat ggcggtgtcg ttagtttttc tacgtttcct tcacggtctg ttctcgtcaa
    39781 ctctttgaag tcttctgttt ggatgacttt tgctccggca aattctgtcg gtgcttcttc
    39841 acggaatttt tccatcaaag cagagatttt tgcagaacct tcttgtccgc tcattgtcac
    39901 agaaatcgtt ttttctgcgt agtagccata tgtttcaaaa atcgtttgca agccgtcata
    39961 caacgttttg ccttgttttt tatagtaagc tgctacttct gctaataaga gcaatgcttg
    40021 aatcgcgtct ttgtcgcgaa cgaaaggttt aactaaataa ccgtaacttt cttcgaatcc
    40081 gaacataaaa gtatgggaat gatcttcttc aaattgttga attttttcag cgatgaattt
    40141 gaatcctgtc aatacattga acatggtagc cccatagtgt tccgcaattg ctgtaggcaa
    40201 ttcgctagaa acgattgatt tcaataccgc tgcattttca ggtaaagtgc ctcgcgattg
    40261 gtgtgcttcc aaaatatatt gagcaaacag ggctccgatt tggttccctg tcaatacttc
    40321 ataggagcca tttggcaaac gaacggctgc gcctaaacgg tctgcatcag gatctgttgc
    40381 aatcagtaag tcagcgcctt ctttctcgcc aagtcgcatc gcatactcga aagcagagtg
    40441 ttcttctgga ttcggtgatt tgactgtagt gaaatccggg tctgcgacag cttgttctgg
    40501 aactagtacg aattgttcga atccagcttg tttcaacgca cgttcgccca acatttttcc
    40561 tgttccgtga agtggtgtgt acacaagttt caaatcttta cccattgttt ccaccaattc
    40621 atgatcaatc gttactgctt tgatttcttc tagataagcg gcatccactt cttctccgat
    40681 gatcgtgatc aatccgctat gttcagcttc gtcgtcagat aatacttcaa cttttaacgg
    40741 attgctgact tcacggacat atttcgtcaa tgcatctgcg tctgcaggag gcatttgtcc
    40801 cccatcttct ccgtagactt tatatccgtt gtaagctgct ggattgtggg atgcagttac
    40861 catgattccc gcaaacgtct tcaaatgacg gactgcaaaa gaaagctctg gtgttggacg
    40921 taaactttcg aatacataag aagggatatt gtgatgtgct aatgttttgg ctgcttccat
    40981 ggcaaattct ggtgattgat ggcgtgagtc ataagcgata gcgacacctc ggcgttttgt
    41041 ttcttcacct tgtgtatcca tgaaacgtgc aagtccttct gttgcttgtc ttaccgtata
    41101 gatgttcatt cgattgatcc caggtcctaa gattccccgc atgcctgcag taccgaattc
    41161 caacggtgca taaaaagcat cttcaagttt ttcaggatct tcacccagat caattaattg
    41221 tttttttaag ttttcttcta aattttcttc atgtacccat tgttcataca cttgttccca
    41281 agacatgaaa ataacacctc tttctgaaat atggttctta ataagtatag cattcactta
    41341 ttagatatga aagtacgagg tctaaaaaac gcttaaatca agaaaggatt cttttatcaa
    41401 gcacggttgc aagtattcgc ataaatcgga ttcagtagat ttcacgcgaa aaaaaagagt
    41461 aaaagaacaa ttgaaaccgt tcttccactc tttttaaact tatgcagttg tttcttctaa
    41521 agattccaag tatttataca cttgttgtcc agcgatccca ccatcaccaa cagcagtagt
    41581 gatttgtcgc aaatcttttt cacgaacatc tccgatggca aaaacgcctg gtatattcgt
    41641 cttcatttcg ttgtctgttg gaatccagcc agcttcgttc gtcaaccctg cttctctaaa
    41701 tggtgcagtt aatggatcca gtccaacata gatgaatact ccgtctgctg ccaaatcaaa
    41761 ctcattgccg gttttgacat tacgtgcttt cacacctgtc actaccattt cattcccaac
    41821 gatttcgtca acgactgtat cccacataaa ggaaattttt tcattcgcaa atgcacggtc
    41881 ttggatgatc ttttgtgcac gtaattcatc tctacggtgg acgatgacta cttcagaagc
    41941 aaattgtgtc aaatagatgg cttcttctac tgctgagtct cctcctccga tcactactag
    42001 acgtttgtta cggaaaaacg caccatcaca aactgcacag taagaaacgc cacgtccagc
    42061 aaattcttcc tcgccaggta cgcctaattt acggtggata cagcctgttg cgataatgac
    42121 tgtttttcct tcgtaagttt tatcttcaca aataacttct ttgtggctgc cgtgatcctt
    42181 gatatcttgc acgattccat aagcattttc tgtcccaaat cttgaaacac cttcatacat
    42241 cttataagct agatcaggac ccatgattga atcgaaacca ggatagtttt cgatttctgc
    42301 cgtattgttc atttggccgc caggggcgcc ttgttcgatc atcaatacgg ataagtttga
    42361 acgtgaagca tataaagcag cagtcatccc agcaggacct gcgccaataa cgattacatc
    42421 atacatatgt agattctcct ttacttaatc aagtaagcat actttacagc caatgcgaaa
    42481 aaaagtctat tgttctgctt gcgtttctcg aatagcttta ttatactcga aaaatccgct
    42541 gaaaaacaat agacttttac aaatcattga tcaatcattc gaaagatttt ctccatttga
    42601 atcaattact tttttatacc agttgaatga tttcttcttc gaacgggcta atgtgccatt
    42661 tccttcgttg tcacgatcga cataaatgaa tccgtacctt ttcttcatct cacctgtacc
    42721 agctgatact aaatcaatac atccccaagt cgtatagcct aatagatcga ctccatctaa
    42781 ttctactgta tctttcattg cctggatatg tgctgccaga tagtcgattc gatagtcatc
    42841 ttccacataa ccattctcat cgggcgtatc gactgcacct aagccgtttt ctacaataaa
    42901 tagtggtttt tgataacgat cataaatatc attcatcgtt attctcaagc ctaatggatc
    42961 aatttgccaa ccccattcac ttgcttccag atatggattt ttgacagaag caaagatatt
    43021 tcctgcagtc tgttccaaga gttcgttgtc agtagtcgaa actcgagaag aataataaga
    43081 aaaggagata aaatcaacag tatgttcttt cagcaatgcg gcatccccag gttccatttt
    43141 gatctgaatg ccatttcgtt ccatttcttt caatgcataa gcgggatatt ctcctcgtga
    43201 ctggacatca atgaagaaat aattttctcg atctgatttt ctagaagccc aaacatcttc
    43261 aggattgcaa gtgtatggat aatatgctcc tgctgccagc atacagccta ctttgttctc
    43321 cggatctact tcatgagcaa tcttcgttgc gatggcactt gcaaccaact catgatgtgc
    43381 cgcttgatat ttgatttgtt cttcattttc tccttcttca aaatacagcc ctgcgcccat
    43441 gaatggtgca tgaaggatca tattgatctc attgaatgtc aaccaatatt tgacaagtcc
    43501 tttatagcga ttgaagatga ctcggcacag attttcataa aaaccaacga gttctctaga
    43561 acgccacgca ccatattctt tgatcaaatg catcggacaa tcaaaatgtg taatcgtcac
    43621 aagcggctcg atcccgtact tttgacattc tttaaagaca tcctcataaa atttcaaacc
    43681 agattcattt ggctcatttt catcgcccat tggaaaaata cgactccaag caatggacat
    43741 ccgataagtc ttgaacccca tttctgcaaa caaagcaata tcttccttat aatgatgata
    43801 catatcgatc gcaatttttg ctggataaaa atgatcttta tcaaattcaa acattttctt
    43861 ttttccagta atgacaggaa aacggtcttc tccgattggc acaacatcta cgttcgctaa
    43921 cccacgtccg ccttcatcat aaccaccctc gcattgattg gctgctgtag caccgcccca
    43981 taaaaaatct tttctgaatc ccatcatact tcctccatta catgtgtatt gcttgacaat
    44041 tctcttgcca gttcatcttg gacttcgatt ccttctgctt ttaaccggct gattgtttcc
    44101 ttgaattgcg gtaaatactg ctgatgtgca ataaacaact catccatgat ccgttttgct
    44161 gtctttcctg atcgtataag cggattgatc gtaaacgctt gtaaagctgt tccataatca
    44221 ccagtcacgg ctgcttcgat cgtcagcaat tccatattct tcattacttg caaccagcct
    44281 ctttcagcag caggaaggga accaaacgct acatttcgtg cgccttgtgc gccaacatag
    44341 gcagtgactt ctactacaca atctgccggc agatcaggaa cagctccatc attctttgta
    44401 gacaccacga tctgtgtttc tttatttcca tagatcgaag caatcgtttc acaggcagca
    44461 tctgaataat aagcaccacc tcgtttttgc aattgttcag gtttatgatc caattctgga
    44521 tctttgtata attcaaacag ctctgcttct gtttctttca cttgttgcgc tcttgtacca
    44581 atcgtttgat attcttctaa agcatgttcc aacatttctt cttcacggta gtaatagcgg
    44641 tggtagccac aagggatcat gttcatttgt tttaattgtt ctttgaaaaa cgggatgtca
    44701 aagatatttt tcggcaatcc attgtcttca tcgtataaac gatcaatcaa atctgctgtg
    44761 cggtcatttc ctttattatc tgctactttg tgccaatgga agtgatttag accggcaaac
    44821 ttgtagatca gctcttcttt tttcttgcca agcattgctg gttctgtcat cgtcgccatt
    44881 actggcacat tgcataatcc gatcacttta tcccatttgc catatctgat aactgcttct
    44941 gtcaccatcc cgcttgggtt cgcgaaattg atcagccaag catttggaca taaacgcttc
    45001 atgtcttcaa cgattgccaa aaccactgga acggtacgaa aagctttgaa tatcccgcca
    45061 gcaccatttg tttcttgccc aatcatccca taataactag ggatccgctc gtctttgatt
    45121 cgtgcatcta attgaccgac acgaaactga gtcgtaacaa aatccgcatc tttcaatgct
    45181 tcttcccgat ccaaagttgc atagatcttg acttcatacg gagaagcatc ccacatacgc
    45241 tgagacatct gactgacgat ctcaagcttt tcttttcctt cttctacatc tacgagccag
    45301 atttctcgta tcggtaattc ctcatatctt ttgataaatc cttccatcaa ctcgggggtg
    45361 taactgctgc ctccaccaat cgtagcgatt ttgattcctt ttgccatgtt ctcactcctt
    45421 tgctttttac acttttatta tcttttttgt aaacaaaaca aacaatagaa attcgtttct
    45481 ttccagtaac atttacaaaa gttagtgttt tctactggat ttttgtaaat atcttgtcaa
    45541 aaaatgactt tattaagcta tataacataa atccgtttac aaatcatttt caaaaaagtt
    45601 ataatttacg taaaaaaact agaagaaggt atctacatgt tattacgtga aaaaatcaaa
    45661 gaaatctcct tttctccttc agaaaatgaa gtgattcagt ttctcttaag cgattctcca
    45721 gcacttggcg aaatgaccat ccaagagatt gctgagcgat gttatgtcca cccgtccaca
    45781 ctcatccgtg tagcaaaaaa aatgggtttt gatggctggg tcagttttcg taatgctttt
    45841 ttagctgaaa cagcctatct tgaagggaat tttcaagacg tagatgcgaa tcttcctttt
    45901 tccaccacag acggtattat gacgatcgca aataaaatgg cttctttaga acagatgacg
    45961 attcaagata cactttctct cattcatcat gaccaactgc aaaaagccaa acaactaatg
    46021 cttcaagcaa aaaaaatcgt gattttcgcc agtaactcga atactttgat ttctcaagat
    46081 ttcatgctga aaatgaagcg catcaaaatg gatgtcacga ttgtcaccac ttttggtgaa
    46141 tcgttctatg aagcgtacaa ttgcacgagt gatatgtgcg ggattctgat ttcttatacg
    46201 ggtgaaaaca atgtgatcct tcgtaccgca gaaatattga aacaaaatca tgttccaatt
    46261 ttagcgttga ccagtatcgg tgattcaacg ctatcctcaa tgagtacagc cgctttgcga
    46321 cttacgacac gcgaacgact gtattcaaaa attggtaatt ttacgatcaa tacatcgatt
    46381 tgttatcttc tagacgtgtt atatagttgt gtttttgcag aaaattatca acagaattta
    46441 gtccatctaa tttctgtagg acaaaaattt gataaacgcc ctatcagctc agccatcatg
    46501 aaagagcctt tcaattttga aaataaagaa gtggactaaa aagaatagtt aagtctattc
    46561 cattctttca cctaaccgtt caggtcagtg cggtgataag tgcatcgtct ggcccgaccg
    46621 tctccccttg attttccaaa atatccaaat aatccatgta attggtgacg attacaggtg
    46681 tttctaaact gtatccttcc ttttcgattt tctttttgtc gaagcggagc aacagatcgc
    46741 cttgtttcac tctttctcct tgctgcacca agctttcaaa atatttccct tccaactgaa
    46801 cagtatccaa tccgacatga atcagcaatt ccagacctgt ttcagaaacc attccgattg
    46861 catgtttcgt ggggaacagg gtcatgactg ttccgtcaaa aggggcacgt acttctcctt
    46921 tttcagggta gatcaagatt cctcgaccta gtgttccttg tgcaaaagct gcatcctttg
    46981 ctgctttcag tggagcgatt tgtccttgta tcggtgtttt tacaatttct ttacctgatc
    47041 ttttctgtct gtcatctgtt tcacctgctt cctccttcca aaagaaaaaa gtcagcgcaa
    47101 aggataccac catcgcaatg gcgatcccaa tcaatacatt aatcacatct gttaaatcac
    47161 catctggtct aatatagttg ggaattgtaa agatgcctag tccaccttga ttccaagaag
    47221 ttaaattcat taacccacta tacgcgcccc ctaacgcacc accgacacaa gtaaaaataa
    47281 atattttttt acgtggtaat gtaaacccat aaatagctgg ctctgtaatc cccacaatac
    47341 cagaaacaat ggctggtatt gcaattgctt tgtcttttgg atttctaagc ttaaagtaga
    47401 gtgcggtaag tgctgcagtt tgtccaaaag acactactgc aacaggtgtc ataatatttt
    47461 gccaaccatt cacagaaaat tgcatcaatc ccattggtac gattgcccaa tggagaccaa
    47521 acatcaccag aatttgccag aagaagccta cgattgctcc ataaataact ggcgaaagtg
    47581 ctaaaagtgt ttcaaatcca gccattaaaa tatcagttgc gaatgtgaat actggtccaa
    47641 cgagtaaaaa acctaaaggc attgtaataa gaacggtgaa gaatggaacg aagaaattcg
    47701 cgatcatctc aggtactaac tttttaattg gtttctgaat ttggctagct aacaacacaa
    47761 taaagataat gggaatgaca gaagaagcgt agttacgcgc aatccaggga atgccgaata
    47821 ctgtttgata aataggtgct tcaaaaatag tgccagaaaa tatggtcgtt agtggtgctt
    47881 ctgctgcacc actcaaagct tccagcgaca agctaggatt cattaatgct gcgccaagca
    47941 acatccctac gaattcattt actttaaatt tacgggcagc tgttaaaccg ataataacag
    48001 gcataaattg gaatacagaa tcaccgatat tatcaaacat aacaaatgtg ccagaaccgc
    48061 ggtcaaacgc gcctaagaag acaaggaatg ctgtcagtcc acgaatcatc ccgccagcag
    48121 ctaagatagc aaggaatggt tggaaacagc ccgatattcc atcaataagc atatcaaacg
    48181 gtctcatttt ttctgttgaa acagcctcat caaaagtaag gtttcctgct tttataacct
    48241 cttcaaacac gactggcaca tgattcccga tgacaacttg atactgccct cccgctcgca
    48301 ttaccgttac aataccgtcc atatttttca agatctcatc atttgctttt tcttcgtttt
    48361 ttaatttgaa acgaagcctt gtgatacaat gtgtcaaacc attgatattt tccttcccac
    48421 cgacattttc tacgattttt ctcgctaatt cttggtattt tcccatttct attccctcca
    48481 atatattagt ggaaggttta gccaactgaa tgtcactacc cttatttcat acgttcttgt
    48541 taatttatcc tccttttttt atttatttac aacgattctc atgcactaaa cgcgcagtat
    48601 ggatcgttaa atacattttt tcgtccgtgg acatctggta gttgaacgtc tcggctaaaa
    48661 agtctgctat tttctcaacg caaccaaacg tatccttata ttttttttga ataacctgaa
    48721 acaattcctc agaaacttct cccacttctg atttttctcc atctaggacg cgtgtcagaa
    48781 aaaaacgtaa gtgtgtgacg aatcgaaaaa aatggactga atcttcatca aatgtaatct
    48841 tatagtaata gcggacgata tttagaatat cctgtattgt tatagtaaac aggtaggtat
    48901 tgttttgttg gctttgaatg ccttgtgcat tgactaaatg caatgcgata aatccggctt
    48961 catcttctga taacttgatg tggtatttat ccgagatttt cttcactgtt tttttcccga
    49021 tggcatactc tttaggaaat agttgtttga tatcatacag caatacattt ggtacaaata
    49081 ttcccatttt gtgacgttcg atagccgtat acaaatgatc cgtcaatgca atatacacag
    49141 aatcattcaa ctggacttgt agagcctctt ttgtatattc aatgatttca caagaaattt
    49201 ctaagtactc aagaggaatc gcttgtgcca attcttggaa ctgttgtgaa agcccgtcat
    49261 ttgtcaactg aaattttttg tcgatgcatg agtcaaaaat cgggtcaccc actttctttt
    49321 tgaatgccaa accttttccc atcacgatca tttcctgatt tctttcatcc ctggttatta
    49381 cgacgttgtt attcagtact ttctcaatca gcatgttttg ctcctttcca tgatatatag
    49441 ggctgtattc aaaacaaaaa gaaaaaccca aaaagccgtc catggaacca tgggagactc
    49501 atcaggttta gcttgcatca ggcaatcact atccaagttg tatcgttttc tttatattat
    49561 cgaaagcaaa cgcttttgtc aacgctttct tagtggctat taggcacttt tgactagctg
    49621 tcgtcgtctt ttttaaatcg ggtgactacg ccactaacgc tcacagatga agaatctggg
    49681 aagctctgtt ttattttcac tctagcgctt aggacaaaat gctactatgc tactgtcaca
    49741 acctcttttt acacaccact gctttgcagt ttgtacatat ctgcatacaa accattttgc
    49801 gctagaagtg tttcatgatt cccacgctct actatatgac ctttgtctaa aactaaaatc
    49861 aattctgcat cccgaatcgt ggacagccga tgggcaatcg caatcgttgt ccgtccttgt
    49921 cgcatttttg ccaatccttc ttggatcaat ccttcggttt cagtatcgat atttgctgtt
    49981 gcttcatcca atactagtat tttaggatct gtcacgattg ttcgcgcaaa agtgatcagc
    50041 tgtcgttgtc cactagaata gctggcaccg tgttcgatca cttttgagtg atatcctttt
    50101 ggtaattcat cgatgaactt gtttgcttga acaaactcag ctgcatggcg aatctgttcg
    50161 tctgtgatag ctggattcat catccggata tttcctgcaa tatctccata aaacaagaag
    50221 gcatcttgca agaccaatcc cattttctta cgtaactctt ccattggata ttctcgaatg
    50281 tcatgatcat caatcaagat ttggccttca taaaattcgt aaaaccgcat caatacgttg
    50341 atgatcgagc tttttccgct tccggtgtgc cccactaatg caacggtctc acccggatta
    50401 gcgacaaaag agatattgtt caatacattg tgctctccat cataagaaaa gcttacattg
    50461 cgaaactcga tcttacctga agtaatcgct tgatctgctc caggattttg ttgcggtgca
    50521 tattcttctg tatccatgat tttcaaaata cgactaccgg caaccatccc atctgtaaag
    50581 gtgctcaaaa agtccatcat ttgagacatt ggattaaaaa atccctggac ataggtcgta
    50641 aatgcataga tcagtccaac ttctacggga gaatgcaacg catcgatccc aaacaaagtc
    50701 aacgccaacg caatcgccaa tgcatagaga aaattgatga tcggacttaa cagaatcgaa
    50761 ttcgttttga tcatcgcata gcgcgtgtct aaatactcgt tgttcacttg ttcaaattct
    50821 ttagctaaac gagcttcttg gcgaaactgc tggataatac gcatgccgga aatcgattca
    50881 ttcaatttcg tgttcagctg acttaatttt tcccgcatat ttcggtaaat acgagaactg
    50941 aatttctggt aataccagat gacgattcct aaaatcggca agaacaccaa agtccacaag
    51001 gcaatttctc cattgatttg aaacatggca acgaaagaag aaacgactgc aaagatccca
    51061 gtcaatacca tcaaaaagac ataccaaaat tcaaatagcg tttctgtgtc attcgtcact
    51121 cgagaaacgg tcgatcctgc cggtgtctgg tcaaaataac gcatacctag tgtatgcagc
    51181 ttttcaaata atcttacccg aacatactga taggtcttca atgaagccat ggaatacaaa
    51241 taccattgga aaaaccaaat gatacttttg actatgactc caaacaagta cacaccagca
    51301 aaaaacaaaa taacttgtgt cgtagctgac tgtttagcca gatgatcatc cataaaagtt
    51361 tggatgatcc ttggcaatag gacattgatc acagacaggg caaacgcaaa taagatagca
    51421 acgatgaacg ttcttctaaa aggtttggcg aacttcatca gtcgtttgat gatcttcttc
    51481 tgttctttaa gtggaatcga ttttgtccat tccgattgat aattttcatc catcaggcct
    51541 cgcctccttc tatcttcgct tctaattgct gtttttccca cattcgttca taccagccac
    51601 ctaatgcaag cagctcgtgg tgggttcctc gttcaatgat tttcccttga tcgacaacaa
    51661 tgatttcttt tgcatgcatc acgctgctta aacggtgagc tgcaatgatg gttgttttct
    51721 cttttcttat ttcttttaaa ttatgcaaga tagcttcttc tgttttggca tctactgcag
    51781 aaagtgcatc atctaagatc agcaattcag gatttttgat caatgctcga gcaatcgaaa
    51841 tcctttgttt ctgtccgcca gataaagaga ctccacgttc tccaactaag gtatcataac
    51901 cttttggcaa ttccttgatt tcattgttga taaatgctaa agaagccgca tgctctactt
    51961 cttcttctga aagttttgga ttagaaaaac ggatattatc tcgaatggtc atcgaaaaca
    52021 ggaagtgatc ctgaggcaca taaccgattg atcctaataa agcattcaat gaatattctt
    52081 tgatcgaacg tccgccaaat tggattttcc cttgataatc atcgtattca cgcatcagta
    52141 atttgatgat tgtcgttttt cccgcaccag ttttcccaac aatacctaat gtttctcctt
    52201 cttggatcgc aaatttgatt tgttctaatg ctggtgattc ttctttcgga tagttaaaag
    52261 aggaaatagc tacattcagc tcgccttttg ccggggtctg cactgcaccc agttgttcca
    52321 cgatatgcgt cttttcatgc aaaagttcat taacgcgatc ataagaagca tttcctcttt
    52381 ccaatacgtt gaacaatcgg ccaatcgcaa acatcggcca aacaagcata ccgatataac
    52441 taataaatga gaccatctgc ccaatcgaga tcgtgccttc caagacatac tttccaccta
    52501 aaataattgt tgcaacataa gacagaccga taatcaaggt aatgaatgga tcaaataagg
    52561 agtctaaaaa attgactcgt ttgtttttaa taattgcatc ttcaatcttt tcttcaaaat
    52621 ccgcgagatc ttctttttct tgtccaaatg ttttaatgac tttgatccca gtgatacttt
    52681 cttgtgtctt atcattgata ctagaaaaag cttcttgcga atcacgaaaa gcatcgtgga
    52741 gttttgaccc cagcactcgt gaagtaacgg ctagcaaagg cagaggaatc agcgcaatca
    52801 gtgttaagcg ccaatcaata aacaaaatca tcgcaatgat cgttgttccg cccgtaatca
    52861 ctgaatctgc aaaggtcaag attccagctc ctgctacatt ctggattgca ttcaaatcat
    52921 tcgttgcatg agccatcaaa tctccagtcc gatatttttg gtaaaagaga ttgtccattt
    52981 ctgtaaaatg tttgaatagc tgctgccgaa gttctttctc caaccgagct gcacttcccc
    53041 aaatattcgt ccgccagata taacgaaaaa gatattgtaa gaaagctgca aggatcaata
    53101 gtaagatcca ccaagaaatg atctttattg ataaattctt atcggcgatc tcatcaatga
    53161 tgatcccaat cacttttgga ggaactaact gtaccaaggc cactgcgaat agggagaaaa
    53221 tcccaattaa ataatgtttc ttttcctgac gaaaaaacca acctaatttt ctaaaaatcg
    53281 acattttact cctcctttgt ctttatcaag agcataggat tgtctgtcct tgtctttttt
    53341 gctgaatagt ctgaatagtc taacaaatta cgaaataaaa aacggactga aaaaatcagc
    53401 ccgcaaaaag tctttgggtc agaacctatt ttttcccttg gttcttcatt tgctgcatca
    53461 tctggcgaat tttcttctca gatggttttt gccccattga catcatcatt gatcgcaaca
    53521 tgtcctcatt aacgggagga tttttttcta aatagtcttt catatattta cgcgctagga
    53581 aaaagccacc tactgcgccg attagcaaag caataatagc aataagtacg acaatacctg
    53641 ttgataccat ataaatctct cctttctatt tccgaattgc tctcaatgat ttattttact
    53701 aaagtttatt gaaaaaagaa aggcgtattc tttagtttca tgcaaaaaat agtggttttt
    53761 ttagagaaga acaaaatttc tttcattaac cagcaagaca cgccacgaaa aaaaattagg
    53821 cataccgaat ctttttcttt aattttttct ttctgaggtg tagaatgtaa tcgtagataa
    53881 ataggaaagg tggttttttc ttgaataatc aatccaacaa acaatttcat aagcatcgac
    53941 ttattgaaca tacaaatggt ttatctttag ctgaagtaaa tggaacagtg gatgtaccaa
    54001 agggaaaaag tttttttaaa acacttcttg cttactctgg accaggtgca ttagtagcag
    54061 ttggttatat ggatccaggt aactggtcca cttcgatcac tggtggacaa aatttccaat
    54121 atttattgat gtcagttatt ttgatgtcta gtctaattgc tatgctttta cagtatatgg
    54181 cagcaaaatt aggaatcgtg acccaaatgg atttggccca agcaatccga gcacggacaa
    54241 gtaagacatt gggtgtcatt ttatggatct tgactgaatt agccattatg gcaacagaca
    54301 tcgcagaagt cattggtgca gcaatcgccc tctacttact ttttgatatt ccattggtaa
    54361 ttgccgtatt tatcactgtg ttagatgttt tcgtcctttt attgctgaca aaagtcgggt
    54421 ttcgtaaaat cgaagctttg gttgtctgct tgattttcgt cattttattc gttttcgtct
    54481 atcaagttgg cttgtctaac cctgattggc acagtttatt tgctggcttt atccctaaca
    54541 gtcatacatt ctcagactca cctgtcatag gtggtgaaac tccgctgact ggagcgttag
    54601 ggattattgg tgcaacagtc atgccgcata acttatatct tcattcagca gtttctcaaa
    54661 ctcggaagat cgatcaccaa gacgaagaag atgtagcaca agcggtacgc ttttctactt
    54721 gggactctaa tatccagttg tcaatggctt ttttagtcaa tgcactgcta ttgatcatgg
    54781 gtgtcgctgt attcaaaacc ggttctgtcc aagatccttc cttttttggt ctgtatgaag
    54841 ctttatctga tccatcagct atgagcaatg gtatcttgat tgctgtagca aaatctggta
    54901 tcttgtctac tttatttgct gtagcacttc ttgcttctgg ccagaactct actattactg
    54961 gtacgttgac cggtcaagtc atcatggaag gattcatcca tatgcgtatc ccgatttggc
    55021 taagaagact agtcacacga ttgctttctg tgattcctgt attgatttgt gttttgttta
    55081 caagtacaaa aggaacgatc gaagaacata ccgctttgaa taacttgatg aatgaatccc
    55141 aagtttttct ggcttttgca ttgccattct cgatgattcc tttactgatg atgaccaata
    55201 gccaagcgga gatggggagc cgattcaaaa attcatttgt tgtaaaactt cttggctggt
    55261 tctctgtgat tagtctgact tacttgaact tacgaggatt accaggtcaa atcgaaagtt
    55321 tcttcggcga gcaagccacc tcagctcaac tagcattggc tgatcaaatc gcctatgtaa
    55381 tcattgttct tgtccttctc ctgttggcat ggacgattgg tgatttatat aaaggaaaca
    55441 aaaaatatga acagcgtttg caagaaacga tagaagaaat cgaatagaaa ctgattcttt
    55501 tacacaaagg aggttgtgac agaagtgggc agcttcaaga aataagaagg aatttaagaa
    55561 aattgctttt caaatttttg tgaaatttcg gcttatttcc gaagaagtta cttctggaac
    55621 accgtgtatc agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca
    55681 aaaatagttc ctcatatttt acgtttggtt gagcttatta ccgcagatgc aagcttttga
    55741 gcaccgttta ttcggaaaaa ggaactgcga caagactttt gtcacagttc cctttttatt
    55801 tggaagataa agcttttttc agattcaatt tactaaaaac tagcatgctt gttactgcga
    55861 tgaattgcgt taatggcacg cctgcgccag tgtagacact taaaaaataa tccttttttt
    55921 ctggcgcata agaacaaaac cacgagacac cgaaaagaaa aaccaattgt gtcagtatta
    55981 atccgatgac tacaatcaaa gaggaactat aataggcacg atcagctttt gcaaatacgg
    56041 ttcctagtat cataagtaat atccctgcta ttgaagcaat cagcacggga atggccagaa
    56101 cttggtaaat ttttatcatg acattcgcga cttttgctgt ttttgtcaac tggaaatcag
    56161 gtgttctcgg atcactgcta tcgatccaat tatccattag tggaagattc aataattctt
    56221 gtgcctgttc gacttgttct tgcgtcccaa aactataatt ccccccttga tggaaatctt
    56281 tgtatcgcca tgcataagca tatcctgatt tcagaaaatc aaatacgatt ggcagatcat
    56341 tcatcgtctt tccatcccct gatcccatca gatagaattc ttttttcttt ttgatagttc
    56401 ccttttgata ggcttcttct aattcttgat tgactttttt ccaaaaatca ttggtttctt
    56461 ttgcattgtt ttggtaataa ccagattcgc ttaccacatc tcgcaatgcc caaaaaatga
    56521 tatctcctgg taattctttt acttttccgc cttgggtcca cgcatgagtc gtatacaatt
    56581 cgtcaatacg agtagaaaca gtatgaaatg taggagatgc gtctaaagct ttatttaatg
    56641 cagcatgcga gacccatatc tcactgtttt ctttatttaa gtttgtttcg tcatctattc
    56701 ggatcagctg tttcatcaaa cgtccaaatt cgccactcga acggtcattg atggctgcaa
    56761 taccatatgt tgtctcgttt ttatattcga tccactgata gacgatggag aaaccgacta
    56821 gagggagtaa aaacaatgaa agtttcagcc attcttgttt cgaaaggaga aatggtcgtt
    56881 cttttaactt ctttgcttct ttgaaagaaa agtcttgtcc tagcaagatc tgaacgaaac
    56941 tgatgcctaa cgcgactaca gtaaaaggaa gaagccagat ggaatcttcg cgaatgaacc
    57001 aaaagaaagg aaaagaaaca gctagcccta aaaaccacgg cagcaatttt ttgctggaat
    57061 tatatttgcg gtaataaata gctagtaaac aagcgataat gatctcaaca gtcgggatca
    57121 cgagagcatt acgatatgtt cgagtggaat attcatgtgt aaaactaatc ggagaaaaca
    57181 aaaaataaaa atagatactt aaaagaagat acttgttctt cacgattggt ttaaacgcta
    57241 gtgcaaccaa tatactggca agaatactga acatgccgaa taaaactgca taagaaagat
    57301 gcagtttatg tgcaagtact aaaaacaagc tgtaggaaat cccttttgaa agtgtcgtag
    57361 tcgtgtactc ccctagccat ttaccatcca aaatattttg agcatagtga atcagcagct
    57421 gatcatcata ggtcgccgac atatctgttc catagattgc tttactatat aaatacaacc
    57481 gaataattgt aaataatacg gctatgccaa gaataaagta tgtatgtttc ttttttagtt
    57541 ggtcgatcaa ggggtttaaa atgttcagca tcttttcgtc ctttcaatca cgttttgcta
    57601 cttgtttgtg aaacttttcg ttttttactt ttctatcagt ataccctgtt tgtctgaatt
    57661 taaaaagagg gggcaaaagg agcatggcga aaacgaatgc aaaaagcact cctttgtttc
    57721 ttaaacaaaa aaggacaagg cagactgccc aatccttttt tgttgctgtc aggtagaaaa
    57781 cttaaagtgt gacttcttct gctaataact cagggaacac ttcgggatcg aatgcttgcg
    57841 ctttgaacat ggaaatttct tttccatatg gtgcgtaagc tttcttttta tctttaccga
    57901 catatggggt ttctaatatt ttcgaaatgt tgtcaaacat tggatcatgg acgattttgt
    57961 tcaatgtgtc aaatccaatt gttccaaaac cgatattggc atgccgatct ttatgagaac
    58021 cttgaggatt tttagaatca ttgatatgca gtactttaag ccgatctaat ccgatgacct
    58081 tatcaaactc ttccattaca cctgaaaaat cttcttttat attatatccg gcatcattcg
    58141 tatgacatgt atcaaaagta acggataatt tttcattcaa ttttactcca tcgatgattt
    58201 gcgctaattc ctcaaatgtt cgaccgattt ccgtaccttt ccctgccatc gtctccaaag
    58261 cgatctgtgc cgtctgttct tttgtcaaaa cttcattcaa cccctcaata attctagcaa
    58321 tcccagcttc tgcccctgct cctacatgag cgcctgggtg aagggtgatt tgagtagcac
    58381 ctaaagcttc cgcacggaca atctcttctc tcagaaattg tacagcaaat ggaaacattt
    58441 ctggtttgat cgtatttccc aaattaatga tataaggcgc atgaacgacg atatttgtta
    58501 gtccgttttc tgccataaat gcttttccgg catcaatatt catctcttcg atagcttttc
    58561 ttctagtatt ttgaggagcg cctgtataga tcataaaggt cgaagatccg taactggctg
    58621 cttcttctgc cgcgcctaac agcattttct ttccgctcat gctgacgtgt gagcctaata
    58681 acatggatgg attcctcctt gaaaggcaat tgtttcgaac aattcctgta tattgataag
    58741 atgatgtaca aagaaaatag tttgtttttc tttgccctgt tctccatagt aactgaaact
    58801 ttccctaaag aaaagcttaa gaactctttc ataaaaaaga tcatttcctc acgttttatc
    58861 tcattcgaaa aagaaattcc tgtcaaaaac agccttgtct gtttttttgt cctattattt
    58921 gctataatta gcgaaataaa accattagtt gaggtgaccc ttttgccacg caaaaatact
    58981 cgaaaaaaac agaatagaag aaaaaaagaa aaatggtttg ttcctaagat tatttttaga
    59041 gtgtttcaat cattgactgt ttttattact gttcttcttt tgttgttcgc agctctaggt
    59101 atcggaatag gtgctggcta ctttgcctat cttgtcgaag acacacaatt gccgactaaa
    59161 aaagaactgc agacagaact aggaaacatt acggaaacgt caaagattgt ttatgcagat
    59221 aatacagaga tatcaaaaat ccagacagat ctgatgcgga cgactatttc atctgataag
    59281 atttcgcctt tattgaaaac cgcgattatc agtacagaag atgaatactt cgataaacac
    59341 caaggttatg tccctaaagc tgttttacga gcactagttt cagaagcgac tggcatcggc
    59401 tcgtctggag gatccacttt gacacagcaa ttagtcaaac aacagatcct aaccgatgaa
    59461 acaacattca aacgtaaagc aaacgagatc gttctttctg cacaagtaga aaaacacttt
    59521 tcaaaagatg agatcattac tacgtatttg aatgtctcac catttggtcg gaataataag
    59581 gggcaaaata ttgctggagt ccaggaagct gctagaggaa tctttggtgt agatgcaaag
    59641 gatgtgactc tgccgcaagc tgcttatatc gctggtttgc ctcaaagccc tatcacgtat
    59701 agtccataca cgaatacagg cgcgctaaaa gaagatcttt ctgccggtct tgccagaaaa
    59761 gattttgttt tattcagtat gtaccgtgaa ggacaaatta cgaaagaaca atacgaagaa
    59821 gcgaaagcct atgatcttac aaaagacttt ctcccacaac aaatcgcgga acagactgac
    59881 agagaattct tgtattatac cgtgatgaac gaagcaacaa ggattattgc acaacaattg
    59941 gcagaaaaag ataatgctga tatgtcagat tcatcggtca gtgaagctta ttatcaaaaa
    60001 gcacagcaaa cgatccaaaa caaaggatat acgatccatt cgacgattga taaagatatc
    60061 tatgctgcat tgcaaaccgg cgtagaaaat tatggctaca tgttagatga tggtgctggt
    60121 agccaagtgg agactggaaa tgtattgatg gataacagaa ccggacgtat ctatggcttc
    60181 gtgggtggtc ggaattacag ccagaatcaa aataaccacg cctttgatac agaacgtcaa
    60241 gctggttcat ccatcaaacc ggttcttgtt tacggtcctg caatcgatat gggacttgtc
    60301 ggatcagaat cccgtgtatc agattatgca acgacttggc aagaaggaaa aaatgctggt
    60361 gagaaaatcg tcaatgcgac caatgaaggg tcgaacacct tccaaaccgt ccgtgagtca
    60421 ctggaatggt ccaacaatat cccagcttat cacttatatc aagatgtgtt gaattccggt
    60481 ggatcgaaac aatacgctta cgagcactac ttggcgaaga tgaactaccc agcaaatgat
    60541 aattggggcg ttgaatcggc tcctttaggg acagtagatg taacgacgct tcaacagaca
    60601 aatggattcc aggccttagc aaatggtgga gtctacgaag aaggctatat cattgattcc
    60661 atcacagata atgcaggtaa tgtgatttat aaacatgaaa gtaattctgt ccgtatttat
    60721 tccgaagcaa cggcatcgat catgaatgac atgatgcgta gtgtgatcaa tgaaaaaatc
    60781 actacaccat tcaaagatgt catctcaagc ttaaacggaa atctaggaaa tgcagattgg
    60841 gtcggaaaaa ctggttctac caatgaatac cgagattcat ggctgatcgt ctcaactcca
    60901 tctatcacta tcagtagttg ggcaggacac gatgacaata ctggaatgga cagccaagca
    60961 agaatacgtt cggctaatta tcttgccaat ctaatcaatc aagcttacca agcaaaccct
    61021 gagattttcg gcactgatga gaaatttgac ttatcatccg atgtgatgaa gaaaaaagta
    61081 tctgggttca caggacaaac agctggaaaa gttactgtca ataaaaaatc tatccaaacg
    61141 ccaggaaaaa cagtggaatc actttgggca aaaaatggtc cgaagaaaag cgcctttaaa
    61201 ttcggcgttg gcggtactga tgaaaactat acagattact ggaacaccgc ttcagcttat
    61261 gctagagcga atccagagac caaagaatca gacgataaag atgattgatc taatagatta
    61321 atcagaatta aagggagctg cgacaaaaat cttgtcacag ctcccttttt ccgaataaat
    61381 ggtgttcaaa agcttacatc tacgatatta agacaaattt atgtaaaaat gtgaaaaacc
    61441 attttcacaa aatttttcta tataacttta ctaacgaaac tgttttaatt tcttttcttg
    61501 tctttggaat aattcggtta gtttttctgc aaattgccct tttactgatt cttttaagtg
    61561 tgcatgtcgg ttagaaaatt cttgagtagc ttcttctgca gtcatttggt ggttttgatc
    61621 tgtcaatcgt ttttctgccc aagtttgctg agatatcccc ataccaactg aacgtacatt
    61681 tgatcgatgt agatttttct ctaattcttt tagtaattgc attaaaaatt cattcataag
    61741 atgatttctc catagttatt tgtctgattt tttgacgata ggaacgttct agttcgtctt
    61801 gctgctgata gagttttcgt cgttctactt gtagggcttg ttgataatgc tcctgataat
    61861 tcgaataact tcgtcttgct tgaaacagag gctcattatc taaagctaag ttctttaata
    61921 catgatgcag tcgctgctcc tcttgctcca tcaatcgtaa tccttgattc ttaaagtgga
    61981 tcaattcatc ttcttgagct tctaattgtc ttcgttcact tcgataatct ctttccaatt
    62041 cttctagttt catctacttc tcctttaatt gaattgctgt gctaattctc gatctcgtgc
    62101 cacgatttca ttgattttgt cttggatctc cttcgccaat gtatcaaagg cctcccccat
    62161 acgtcttgcc ttattgattc gtagcagata gacttctttc gcagaatcga ctaagttctc
    62221 ttttgtggcg cccacactag ctaatgcttc tatgatttcc tgttcagtca acgaaggggc
    62281 gacaacacgt gcttgccgca agccttcttg ccattttttc tctagctcaa aaattcctct
    62341 ttggttgatg cggataactt cttccatagc gcttttcatt tttaccgata acttttccac
    62401 cactaaccta gcttgtgtgt catctaagta aatttgttca ttaactgtca gccggccgcc
    62461 acttaatcgt agttttttac gtatgttgtt cagttcttgc aactgatagg aaaacaactg
    62521 ggtcgcttgg ttttctttct gttgttttcg agctttaaca ttgttttcat tttcaggaat
    62581 aatcagcttt ccattttcat caaacttcca agaggttaaa ctgtgggaag caagcagatt
    62641 caagtatgct gtttccatac tgatccgaac ttcagcacct gtgccattac caccaaaatt
    62701 accgataaaa tcggcgtgat ttcggtaatt ggtgagcata ccgggatttt cttccaccca
    62761 tttttttgct tctggtgata agagatcata cgggtccggc ccgttgaagc cgacattttt
    62821 ccattgtttc tctgctgcta catataatgc taagaatcca cctaatgaat ggccggtagt
    62881 agaaatagca gcttctccat attccttttt tacttcatta gcaaatgcaa tcgctgaatt
    62941 gatttgcccc gctgttttca atccactaac ggataaaatc ttgtttgttg ttgctttttc
    63001 agaaaaactt gctcctggtc tattcccata gagattcata acacttcttg catccgtttc
    63061 caaatctttc caatcgctta agttcgttcc tgcaaaagca atcactactt gagaaatatc
    63121 cactttaccg ttcttgattg gcgctacagc catcgcctgc atgccgtcga aggagttttt
    63181 gatttttagg atttggaatt ttgtttctcc aaagttttta atggcgcctt ctttgtaact
    63241 tttactatat tgaggatgtt ttggatctag ccaatatact ttattactta ttcctttata
    63301 ctgcttatca gtaattgtca tactttttcc tcactcccat ctgtatagat aactataatc
    63361 tcatcaaccg taatcccttc tttttgtact tcttcatttt caacaccata gccatctatc
    63421 tcattgcttt cttttgtaaa gctataatca aaataaacgg cttttccttc tgtattggtc
    63481 atcgttatca atgcttcata gattcctgtc atgtcgtttt tctcaaattg ttcgattttc
    63541 acttctttga tatccgcaaa ggtatttttc agaactttga cggactgttt ttctactgcg
    63601 agtaaatctt gctgtttttg cgcttctctt ttgtccatgt aaaattttcc tccgattcct
    63661 atagtaagaa tggtcaaaat gatgactatg gtctttcgtc ttttcttagg caaatagaag
    63721 tctcctttcg ggttatgtat gatggattgt ttctccttta agataagtac gcaatcgagc
    63781 ctggattttt ttggattttt tagagttact tttctacttt tctactttct tttttatcac
    63841 gttttcattt taaagtaatt ttgatagtag tgaacaaaat gtagcatcta cgcacagatt
    63901 gtgtcgtata cgatggacgt aaggtttgtt tccgccattc tctctttttt ttaaagtcac
    63961 aaaaaaaggg gttatgacaa aattttgtca taaccccttt tctcgtataa aggttgttcc
    64021 agaagttgac cactttggga acaaccttta aatgattgat cttttattat ttagttgatc
    64081 ctttttcttc gattccataa ggcaagataa tcgttttttc ttcgacttct tctttattca
    64141 tcattttcgt caataggcgc atggataccg ctcctaaatc gtataatggt tgtgtgatac
    64201 ttgtcaaacg aggacgagct acttctgtca gtaaagaatt gttgcttgtg atgatttcga
    64261 attcttctgg tacttttacg ccgcggtcta ataaaccatc caagatacca atggctaatt
    64321 catcgtctga aacatagaca gctgttgcac cgctattatg gatccggtca actagagaca
    64381 gaccatcttt aaagttgtat tgtgcctcaa aaatcaatcc ttcgctatat ggtagattgt
    64441 tttcgcttaa tgcttcttta tagcctttta gacggttttg accattgata ggatcaatca
    64501 gcgcaccgct gacaaaagcg atttttttat tgccgctttt tgctaattta tttactgcat
    64561 cttttgttgc tgatacataa tcaatgttta cgctacctac ttgttcatct ggatcaatgg
    64621 aaccagctag tacaacaggc gtttttgaac gtgaaaattc tccacggatt tcgtctgtga
    64681 tatggtgacc cataaagatc acgccgtcca cttgcttagc caataaatta ttcaatacat
    64741 tgacttcttt ttgatcgttg ccatctgagt ttgctaagat gatattgtat ttgtacattg
    64801 ttgccacatc gtcgatacca cgtgctaaag aggcaaagaa catattgctg acatcaggaa
    64861 tgattacccc aactgttgtt gttttcttac ttgccaagcc acgtgcgact gcatttggac
    64921 gataatccaa gcgatcgata acttccaaga ctttttttct tgttgctggt ttgacgtttg
    64981 gattgccatt tacgacacgt gaaacagtag ccatcgaaac atttgcctct ctcgctacat
    65041 catagatagt gattgtttgc ttttccattt gtgttctcct attcatattt tatatgtttt
    65101 ctgaaaatac gtcttacatt tctaaaatag gatatcaaat aatctcaaca attgcaaccg
    65161 ttttatctct gttttcatga aaatttttac ttttttcagt tttaagaacg ttggtctttt
    65221 aatcaatcag tggtacaatt attgaataca aaattaattt agaaagtagg ttgccaaatg
    65281 aataacgtaa aaatcaatga actacgtcaa tggatggcac aacaccaatt agaattggct
    65341 tatatcagcg accctggcca catcgcttac ttttccggat atgaaagtga tcctcacgag
    65401 cgtgtactag ctctttttat ccctctggaa caagatcctt tccttttcac tcctgctctg
    65461 gaagttgaag atgctcaaaa cagcagctgg gcgtacgatg tacgtggcta cttagacagc
    65521 gaaaatcctt gggagatcat cggaaaagag cttcgcgcac gctatgggca acctggtaat
    65581 gtaggtattg aaaagaatgc tctgactgtc gatcgcttcg atgctatctc tgatatcttg
    65641 acaggtacag attcttacac cgatctaact tctattatcc agcgtctgca actgatcaaa
    65701 acggtagaag aaaaagacaa actgatcgaa gctggtaaat gggccgatgt tgcctttgaa
    65761 attggcttca aaacagtaaa agaaggcgta actgaacaag caattatcgc agaaatcgaa
    65821 taccaattaa aaaaacaagg tgtttcacaa atgtctttcg acacattagt ccttgcagga
    65881 gcaaatgctg caagccctca tggtacacca ggaagcacga aggtttcacc aaatgaacta
    65941 gtgttattcg atcttggcgt tatttggaat ggctattgca gtgatgctac tcgtacagtt
    66001 gcttatcaaa aaccaactga attccaagaa aaaatctata acatcactct tgaagcacag
    66061 cttgccgcac aagaggcagt tcgcccaggt gtgacagcag gtgaacttga tcaaatcgca
    66121 cgaaacgtga tcaacagcta tggctacggc gaatatttca atcaccgttt aggtcacgga
    66181 atcggaacaa ccgtccacga attcccttct cttgtagaag gaaacgactt agtgattgaa
    66241 gaagggatgt gcttctctct tgaaccagga atctatattc ctgaaaaagt aggggtacgt
    66301 atcgaagatt gtgtgtatgt gacaagtgat ggttgtgtgc cattcacgac tacaccaaaa
    66361 gaattacttg ttttagagta atgaaaataa aaaaggtgag agctggtccg ctctca
//
LOCUS       DBGZHO010000008        60146 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.008, whole genome shotgun sequence.
ACCESSION   DBGZHO010000008 DBGZHO010000000
VERSION     DBGZHO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.008"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..561)
                     /locus_tag="ACN3HL_000715"
     CDS             complement(<1..561)
                     /locus_tag="ACN3HL_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005615.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(616..795)
                     /locus_tag="ACN3HL_000716"
     CDS             complement(616..795)
                     /locus_tag="ACN3HL_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005616.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(872..1381)
                     /locus_tag="ACN3HL_000717"
     CDS             complement(872..1381)
                     /locus_tag="ACN3HL_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005617.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(1477..1857)
                     /locus_tag="ACN3HL_000718"
     CDS             complement(1477..1857)
                     /locus_tag="ACN3HL_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8005618.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            2187..2936
                     /gene="pnuC"
                     /locus_tag="ACN3HL_000719"
     CDS             2187..2936
                     /gene="pnuC"
                     /locus_tag="ACN3HL_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HHC8005619.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(3120..4397)
                     /locus_tag="ACN3HL_000720"
     CDS             complement(3120..4397)
                     /locus_tag="ACN3HL_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005620.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(4476..5120)
                     /gene="pcp"
                     /locus_tag="ACN3HL_000721"
     CDS             complement(4476..5120)
                     /gene="pcp"
                     /locus_tag="ACN3HL_000721"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HHC8005621.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(5319..6263)
                     /locus_tag="ACN3HL_000722"
     CDS             complement(5319..6263)
                     /locus_tag="ACN3HL_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HHC8005622.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(6265..6951)
                     /locus_tag="ACN3HL_000723"
     CDS             complement(6265..6951)
                     /locus_tag="ACN3HL_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HHC8005623.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            7425..7745
                     /locus_tag="ACN3HL_000724"
     CDS             7425..7745
                     /locus_tag="ACN3HL_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HHC8005624.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            7899..8804
                     /locus_tag="ACN3HL_000725"
     CDS             7899..8804
                     /locus_tag="ACN3HL_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005625.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            8801..9574
                     /locus_tag="ACN3HL_000726"
     CDS             8801..9574
                     /locus_tag="ACN3HL_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHC8005626.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(9755..11179)
                     /locus_tag="ACN3HL_000727"
     CDS             complement(9755..11179)
                     /locus_tag="ACN3HL_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HHC8005627.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            11390..11836
                     /gene="nrdI"
                     /locus_tag="ACN3HL_000728"
     CDS             11390..11836
                     /gene="nrdI"
                     /locus_tag="ACN3HL_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HHC8005628.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(11901..13883)
                     /locus_tag="ACN3HL_000729"
     CDS             complement(11901..13883)
                     /locus_tag="ACN3HL_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HHC8005629.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(13897..14793)
                     /gene="murQ"
                     /locus_tag="ACN3HL_000730"
     CDS             complement(13897..14793)
                     /gene="murQ"
                     /locus_tag="ACN3HL_000730"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HHC8005630.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(14796..15857)
                     /locus_tag="ACN3HL_000731"
     CDS             complement(14796..15857)
                     /locus_tag="ACN3HL_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HHC8005631.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(16068..16595)
                     /locus_tag="ACN3HL_000732"
     CDS             complement(16068..16595)
                     /locus_tag="ACN3HL_000732"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHC8005632.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(16662..18164)
                     /gene="eat(A)"
                     /locus_tag="ACN3HL_000733"
     CDS             complement(16662..18164)
                     /gene="eat(A)"
                     /locus_tag="ACN3HL_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HHC8005633.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(18422..19543)
                     /locus_tag="ACN3HL_000734"
     CDS             complement(18422..19543)
                     /locus_tag="ACN3HL_000734"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HHC8005634.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            19669..20610
                     /locus_tag="ACN3HL_000735"
     CDS             19669..20610
                     /locus_tag="ACN3HL_000735"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HHC8005635.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(20760..21656)
                     /locus_tag="ACN3HL_000736"
     CDS             complement(20760..21656)
                     /locus_tag="ACN3HL_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HHC8005636.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTSFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            21925..23265
                     /locus_tag="ACN3HL_000737"
     CDS             21925..23265
                     /locus_tag="ACN3HL_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8005637.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            23483..23926
                     /locus_tag="ACN3HL_000738"
     CDS             23483..23926
                     /locus_tag="ACN3HL_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HHC8005638.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(24191..25609)
                     /gene="nhaC"
                     /locus_tag="ACN3HL_000739"
     CDS             complement(24191..25609)
                     /gene="nhaC"
                     /locus_tag="ACN3HL_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HHC8005639.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(26012..27235)
                     /locus_tag="ACN3HL_000740"
     CDS             complement(26012..27235)
                     /locus_tag="ACN3HL_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHC8005640.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(27266..28105)
                     /locus_tag="ACN3HL_000741"
     CDS             complement(27266..28105)
                     /locus_tag="ACN3HL_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHC8005641.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(28122..28802)
                     /locus_tag="ACN3HL_000742"
     CDS             complement(28122..28802)
                     /locus_tag="ACN3HL_000742"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HHC8005642.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(28804..29877)
                     /locus_tag="ACN3HL_000743"
     CDS             complement(28804..29877)
                     /locus_tag="ACN3HL_000743"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HHC8005643.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     misc_binding    complement(29933..30171)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(30213..30446)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(30523..31194)
                     /locus_tag="ACN3HL_000744"
     CDS             complement(30523..31194)
                     /locus_tag="ACN3HL_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8005644.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(31281..33929)
                     /gene="mgtA"
                     /locus_tag="ACN3HL_000745"
     CDS             complement(31281..33929)
                     /gene="mgtA"
                     /locus_tag="ACN3HL_000745"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HHC8005645.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGKFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIHRFQELL"
     regulatory      complement(34271..34445)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            34618..35055
                     /gene="ndk"
                     /locus_tag="ACN3HL_000746"
     CDS             34618..35055
                     /gene="ndk"
                     /locus_tag="ACN3HL_000746"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HHC8005646.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(35077..35943)
                     /locus_tag="ACN3HL_000747"
     CDS             complement(35077..35943)
                     /locus_tag="ACN3HL_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHC8005647.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(36103..38196)
                     /locus_tag="ACN3HL_000748"
     CDS             complement(36103..38196)
                     /locus_tag="ACN3HL_000748"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HHC8005648.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWMKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVLYWLDIATFIGILVWLTIKKIPIKSQPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFSESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSAIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWNEFDN
                     AQMQRVPLMIHIPGYTKGSVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSPQHD
                     QVVAFRNGNFVTPKYTILGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKSALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNIAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKDNQ"
     gene            complement(38672..39295)
                     /locus_tag="ACN3HL_000749"
     CDS             complement(38672..39295)
                     /locus_tag="ACN3HL_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005649.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(39454..40851)
                     /locus_tag="ACN3HL_000750"
     CDS             complement(39454..40851)
                     /locus_tag="ACN3HL_000750"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8005650.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(40883..41854)
                     /locus_tag="ACN3HL_000751"
     CDS             complement(40883..41854)
                     /locus_tag="ACN3HL_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8005651.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            42228..42653
                     /locus_tag="ACN3HL_000752"
     CDS             42228..42653
                     /locus_tag="ACN3HL_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005652.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            complement(43141..43842)
                     /locus_tag="ACN3HL_000753"
     CDS             complement(43141..43842)
                     /locus_tag="ACN3HL_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HHC8005653.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIHQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(43858..44298)
                     /locus_tag="ACN3HL_000754"
     CDS             complement(43858..44298)
                     /locus_tag="ACN3HL_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HHC8005654.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(44298..44873)
                     /locus_tag="ACN3HL_000755"
     CDS             complement(44298..44873)
                     /locus_tag="ACN3HL_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HHC8005655.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            45113..45322
                     /locus_tag="ACN3HL_000756"
     CDS             45113..45322
                     /locus_tag="ACN3HL_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HHC8005656.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(45720..46232)
                     /locus_tag="ACN3HL_000757"
                     /pseudo
     CDS             complement(45720..46232)
                     /locus_tag="ACN3HL_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(46358..47059)
                     /locus_tag="ACN3HL_000758"
     CDS             complement(46358..47059)
                     /locus_tag="ACN3HL_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8005657.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(47167..48610)
                     /locus_tag="ACN3HL_000759"
                     /pseudo
     CDS             complement(47167..48610)
                     /locus_tag="ACN3HL_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(48624..50489)
                     /locus_tag="ACN3HL_000760"
     CDS             complement(48624..50489)
                     /locus_tag="ACN3HL_000760"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHC8005658.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(50610..51461)
                     /gene="licT"
                     /locus_tag="ACN3HL_000761"
     CDS             complement(50610..51461)
                     /gene="licT"
                     /locus_tag="ACN3HL_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HHC8005659.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(51771..52484)
                     /locus_tag="ACN3HL_000762"
     CDS             complement(51771..52484)
                     /locus_tag="ACN3HL_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HHC8005660.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(52552..52878)
                     /locus_tag="ACN3HL_000763"
     CDS             complement(52552..52878)
                     /locus_tag="ACN3HL_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HHC8005661.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(53001..53228)
                     /locus_tag="ACN3HL_000764"
     CDS             complement(53001..53228)
                     /locus_tag="ACN3HL_000764"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHC8005662.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(53550..54803)
                     /locus_tag="ACN3HL_000765"
     CDS             complement(53550..54803)
                     /locus_tag="ACN3HL_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HHC8005663.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            54864..55604
                     /locus_tag="ACN3HL_000766"
     CDS             54864..55604
                     /locus_tag="ACN3HL_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HHC8005664.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(55690..56448)
                     /locus_tag="ACN3HL_000767"
     CDS             complement(55690..56448)
                     /locus_tag="ACN3HL_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HHC8005665.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(56445..56909)
                     /locus_tag="ACN3HL_000768"
                     /pseudo
     CDS             complement(56445..56909)
                     /locus_tag="ACN3HL_000768"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(56928..57425)
                     /locus_tag="ACN3HL_000769"
     CDS             complement(56928..57425)
                     /locus_tag="ACN3HL_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HHC8005666.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(57493..>60146)
                     /locus_tag="ACN3HL_000770"
     CDS             complement(57493..>60146)
                     /locus_tag="ACN3HL_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HHC8005667.1"
                     /translation="TAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDL
                     YDGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLY
                     GPYLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNV
                     MFEVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQ
                     GDSSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSS
                     AVRFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADF
                     TVTGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNV
                     DLESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKD
                     PDYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLR
                     VPTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTD
                     ENEGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTT
                     VDVIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIP
                     ENQLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPAT
                     KIVVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKL
                     SQPFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFK
                     LVLTKENQIAGNYSAEITWTLADAPTE"
BASE COUNT        17250 a        12649 c        10341 g        19906 t
ORIGIN      
        1 gatattcttt tgcatatgat cataaagatg accactgatc atccgctgac cgacaacttt
       61 gaagtcatgg cgttcgtata attttttagc ctttggattt ttttcatcca cacttagacc
      121 gatgacggag cgattagctt tcttcgccaa tttaggtaat gcttctaata atcgcgaacc
      181 gatgccttgt cctctaaaat cttctgatac actgatagag tccaaatacc attcgttggg
      241 aaacgtttct ttatcaatga acaaacgtgt agacgcatct agctgatatt tctctaagat
      301 aggtaccagt ggctgatcga tgattgattc ttcttcatct gtataaccgt aagcaactcc
      361 tgcaacttta ccgtctattt cttctacgat acctcgtgaa taactgtaac gataatttgg
      421 atcagtgatt gcttcttcta aaatctctaa agtcttttgt tcccctgtct gcttcaaaaa
      481 tggcagttcc atatctttta gaatcactaa gatcaatggg gcgatttctg gagcatcttc
      541 ttttctcgca aaacgaatca tagtttcctc tccttttctc cattctaaca tgcagaaaaa
      601 gaaatcgcaa aatcgttatt ttaaaaaatc ttcaatcttt tcagtaatga aataaccatg
      661 agtaacgatt cttgccgctt cagttcggca ataagggcag acgactggca tttctttatc
      721 attatgttcg actacattat tgacttcttc gtatgcaaat ttttttccgc aattagggca
      781 tttcattttt tccatgttat ctcaacttcc tttcatcttt actctcttag cttactctta
      841 tattgtaaaa aagagaagca atatccttct tctatgcaga tatccatacc tgacggtcct
      901 gttctccatc tattaatcgg actttataat aaggacgttc atctttgact agaagtgtcc
      961 actctttcac ttttgctttt ttcccgtagt agctgactgc ttccttcatc gctgcttgcg
     1021 gttgtttgaa ctcttccgtt ttttctatat caaaaagatg ttctgcggcc ttttccgtgt
     1081 catttcgtac ggttgttttc ccagtggatg gattgactgc tatgacttgt ccttcacaaa
     1141 aaaactggta ttcatatgtt gcattcgtag gattctccaa atctttttca actgcaaaat
     1201 gaatagcaga tatgttatgt tcttttgttt cgttttttac gattgctgct gcttttttca
     1261 atgagatccg atattcctgg tcactaatat catccatgtg aaaagcggca ttgagcagtc
     1321 ccgtcatacc ggtaatccct attacgatga gggcagcaac accaaacatc atttttttca
     1381 ttcttcattc tcctgtttct tttttttaaa gaatatcaag aaatgaacga atgaaaaatc
     1441 gaatgaaacg aaaaaaaagt gacaattttg ttatctttat tcgtgcagtt ctaatggcaa
     1501 tccgtctgga tcaaagaaaa acgtcatttt ttttcctgta aaggtatctt ctctaatcgg
     1561 ttctgattcg atccctaagg actgcaattc tgcaattgtt tcttcaatat cgtctacttt
     1621 gaaagcaaga tgacgcaagc cacaagcttc tggatagttt ggtcgttgtg gcgcattagc
     1681 aattccaaaa atctccaatt cagcacttcc tagtttcaga tctaatttat agtcatctcg
     1741 ttctttgcgg taattttctc tgattacttc aaatcctaat ttattaacat aaaaatcacg
     1801 tgatttctga taatctgaaa caatgatggc tatatgatgg atcgttgtaa ggttcatatg
     1861 agcactccta ttcttcgttt aagctcggat ctatattaat ctccagttcc attgtaaatg
     1921 tgtcagattg aaaaaaatag ctgtttttcc tttttataag aaaaaaggca aaaaaaacag
     1981 aaagtaggtc ctccaagaca ctcttcctgt tcccaatata ataaatgaaa gtaagaaatt
     2041 atattttcaa gaaaacaaac agaaaattat cataacacaa attatttata attgaaagac
     2101 tagttttttt tcaagaaaag catacaatag attgtgttag taaatacaga acacactaca
     2161 tttagtgtct taaggagtcc tcatacatga agtcatattt tcagttttta gctcatcagc
     2221 taaaaggctg gccgcaacaa aattattatc ttttcttttt cagtcttggc tgccaggtca
     2281 tgactcttgt caatagtccc atcacttggc tgtccgttat tacatttatc ggtaccacgc
     2341 ttggtgtatt gtgtatttta tccatcaatg cggcaaaatc agtcaacggt attttaggta
     2401 ttttgtctgc gatttgtttt attatcgttg ggttttcagc aaagaactat ttaagtatcg
     2461 gtgaacagat tgcttatatg atcacattgg atatccccgt attgttaagt aaagaatgga
     2521 atcataatat ggcttcaaaa atccgaaaat tcactggaaa aagctggttt atcgcaatca
     2581 tcagtacttt ccttgtctat cttgtttcag gattcctgat tggtcgttat acagatgatc
     2641 ctcggccgtg ggtagatgcc attgcttttt ctattagctt gactgctggt atcatcagtt
     2701 tcttgcgtta caacaaccaa tattactggt ggttagcttc agggcttgct caaatggtcc
     2761 tttggtatat ttcatttacg catggatctg caagtttggc gatgttcgtg aacagctctg
     2821 tttacttgct gaatgatgtc cttgcattta ccgtttcacc ttggtataac caaaaagaac
     2881 gtgaacgtat gcaaaaaatg gaagaagaat actacaacgc acaacaacac gcataaaaaa
     2941 actgagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg
     3001 gcggaatcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa
     3061 ttttcgtgaa tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctctattttt
     3121 tatagtaatt ccttcagata ctttcttgcc tcatcattga aacgcagtga ttcttctaac
     3181 ttctgataat attccaacgc ttgtttctga gcttcagtaa aacgataatg ttttcctttc
     3241 catttgtcga ttgtctcttg cacatttcca gattggatat ctttcactac tagttgccat
     3301 ttttcttttg agactgtacg gtctttctta tcagcagatt gtatagcttc tcgttcttta
     3361 cgcaatactt ttaaaaaacc atttctgact atccgaggaa tgctgtcgaa gaacccttct
     3421 gtaaaaccat agcgacaata ttgcttccaa ataaatagat agatttttgg ttggatgaat
     3481 cgttggtttt tcgcaaaata ttccatctga gcagtgactt ctggtgttcg ttgacgtttt
     3541 gtctttctca acacggaaat aaatgtttca aaataagcat taggatgtac tggcacttct
     3601 tcatatacga tggattgcca atctttacgt aaaaatgcgc gatagttgat caagaattct
     3661 tctacatcct ttactaattc ttctgcaaag tcgtcaaata gttctttttt tatctgtcgc
     3721 ttttttgact gcccattgat gtgttcactt attttcttga tttcattttc caatgcttga
     3781 taatccgcta tgtaaatcgg catttctact tggcgaaatt ctgcgagccg ctgagctaat
     3841 tttatatccg gtaaatatgg ctgtttcatc cgacgatttt ggtacaagac aaaacagtat
     3901 ttttgccata gtccttcagg aaaatcgata ttcttctgct taagccataa taattcgtct
     3961 aaggccagat caacttttgt cattccctga tggatcgaag ctgccactgt cggagagaca
     4021 tgcaggtgat cggcaaagtg gttgatgcct agttttagga tctttccggt ttttggcgat
     4081 ttaacgatgt attgcacttt taattctcta ccacactcac aatacaattt ttgctggctt
     4141 cgttttgttc gaaaaaacgg attgatcttg aagtcagaaa acacccaatc tgttgcagct
     4201 aaataatgtt cttccataaa acgagagctg attagatatc ggcggtgctt atcgactagt
     4261 tcccgctgtt ttttcgttaa ttttgcatag atctcccaac gttgactgct tgtgtattgt
     4321 ttagaaattt tgatgggata gcttttgctg atttcttttg gaaaccattc ttcaaagacg
     4381 gattgccatt cttccacggc tgtttctttc ctttctaatt acaaaaagct ggctactaac
     4441 ataacgttag caaccagcca gtgtttcttg ctaaattagt gagttgttcc ggcatttccg
     4501 gaaatatctt ctttattttc tactgctgct tcaactgcat aagtcaaaga agaagcaatg
     4561 tcttctaaag acatagaagg cgtacccact ggacgatcga tcacttgatc gggtgagaat
     4621 ggcacgtgga tgaacccacc tcgaattgcc gggaattgtg tttcgatcaa atgaagcaaa
     4681 cgatacatga tatcattgca gacaaatgtt cctgctgtat aagagatgta cgctggtaga
     4741 ccatgatctt gtacattttt tgtcattgct ttgattggca atgaggtaaa gtaagcggct
     4801 ggaccgtttt cttctaaagc cgtatcgaat ggctgatttc cttcattatc agggattctt
     4861 gcttctgcta gattgattgc gacacgttcg aacgagactg ctgaccgccc acctgcttgt
     4921 ccgacacaga tcacgacatc tggttggtgc tgttggatgg cttctttgac tacttgactg
     4981 cttttttcga atacggtcgg tacttccact ttgatgattt cagcaccgct gatttcatct
     5041 ggcatttttt ttactgcttc ataggctgga ttcactttgt ccccaccaaa tggatcaaaa
     5101 cctgttacta gtactttcat ctgttgttcc tccgtccgat tgatttaaca tatggttatc
     5161 ttttatcata ccattttcct tgaacagcgt aaataaagga aacaatagtt taaataacat
     5221 aacagatcaa acttaatata ttcttataaa aaaatagtgt tccactacaa tgttagaaga
     5281 ggttgcgaca attattctgt cacaacccct ctcttctatt atttaaatag aatcatataa
     5341 gcaatttgga aaactagcat aaataacgca ataaacaact ggtttttgat cactccgtat
     5401 ttgtctttca tctccagcat cgctacaggc acgatattga agttagcagc catcggtgtc
     5461 agcagggtcc cacaaaaacc gcaagtcaat gcaaccattc ctattaacgc tggattcgct
     5521 ccatgactaa atacgaatgg tgcaccgatc ccaaccgtca tcacggtgat ggccgcaaat
     5581 gcattcccca tgattaccgt aaatatcacc atgccaagag cgtaaatgat gatgccgatg
     5641 ttcacatttc cttctggaac gatcgtacct actgcattgg aaatcactgt cccaactcca
     5701 gcgcttgtaa ataccgcacc tagagaagct aaaagcattg gcaacatgct taacggccct
     5761 actgtgccca gcatatctgc tgcatcatct aaaaatgtac ttggtcgatt atctcgagaa
     5821 aagaacatca agattagcat ggctgcaaaa acaccgacgc ccacgccgac taaagcacct
     5881 aaattggtaa atagagcaaa caagatcgca aagacaccga tactcaaagc tggaataaaa
     5941 attttcattc ctagtttgtc tgacattttt tccatatatt cttttgatgg aagccggctt
     6001 tctcctttgc tgactttctt agcaattgct ggtatggtca tcgcaaagat caagccaccg
     6061 ttcacgattg ccggaagcca tcttcctcct gcaataacta cccctaagac cgtccagaaa
     6121 aaggctgacc cataacgatg aggattggtt ttatctgtta aatttcttac tccagtgtaa
     6181 atcaatacga gtcccatcac gatataaagg atctccagta atttatcgcc taataaaata
     6241 tcaggatttg taaaaaagtc catcttattg cccctttcct ggataatatt tcttcgctaa
     6301 tttcttttct ttaagataga agtagacact tgccacaact aaagccgtga tagccactgg
     6361 aacttccact aaagcaagct gtcccaatgt tacgtcatat cctagatctt tcagtgttga
     6421 ttggactagc aacgcccctg ctcctccgat gaatagtact tggccaaaga accagcagac
     6481 attttccata gctgaagcca taccttttag ttcttcttca tgcttaggat ggacttctaa
     6541 cccttttgat tcgatggtcc ccaatgccat cggtaaaatg attggacgaa caaatccagc
     6601 aactccacca aaactcacgt taaaagccgc aaagatcatt cgaaagatcc cataaatatc
     6661 tacaatcata ccagcagata ctttcttgaa tcgcttgatc aaggaagccg ctgattcttt
     6721 cagaccattt ctttcaagcg ttcctgttgc caacataatg atgataaaaa tcgccatccc
     6781 gcgattgttt acaaaacttg tacctaaaag ttctaacatt ccttgaatgc caagaccgcc
     6841 agtcaaagct gtaacaacta aagcaaccat tacgatcaat atcgagtcta atttaaatgc
     6901 aaacccgaga ataacaatca agacgcctaa aaggctaaga taattttcca tatattttcc
     6961 tccataaaat gacaatattt ttttaattat aaagcaaaac acataaaaaa tatagttgtt
     7021 ttctcacgaa atagacacta tttttaaata tttttcgtta tttttttatc acaaaaatta
     7081 tcttacttat tgtaaggtaa agcttttttt aatttattgc ccgataatat atagaaataa
     7141 ggtctagtta ctgttttttt taaatgatta ataaataaca acttctttct atgaaattgc
     7201 aaagcattca tcttcttttc cgctaacgat atatccgtca gtgcttggta cactttacta
     7261 aaaagtatga gattgccgat atctggatag gtgtgctata ctacagaaaa agatatacaa
     7321 tctgccaccg ggtaggataa agaggatgat cattccatta ggtctttgaa gggatgattt
     7381 tcctcttttt gtgtattttt ttatagttaa ggaggaatgt aagtatggca tggatggaat
     7441 taatcatagc aggaattttg gaagtattct ggtcaacgat gatgaaatgg agtgatggtt
     7501 tttctaaaat caattattct ttttacacag tgattggcat gattgctagt ttttactttt
     7561 tgtcaaaggc aatcaaaagt ttgccgatga gtctctctta tcctatctgg acagggattg
     7621 gcgcagttgg ttcggtcata attggtgtgg tcttgtttca tgataagctg aatctttcca
     7681 cttggttctt tgtggggatg ctactcatca gtatcattgg catcaagatt actagcggcc
     7741 actagacact tggaataagt actgatcaga aaaaataagc ctttttattt aatattcaat
     7801 ttttttatga aaaaataaga aataagtcca atgacctagc gacttctcca ctcatcaggt
     7861 gtatgcttgt actatctata gaaaaggagt gaatattttt gaaaagtctt tcggtccaag
     7921 aattatccaa gaactttggt cacaaacaag ccctcagcga tgtcagtttt agcttatccc
     7981 ctggcaaaat cgttggatta gtaggtccta atggcgctgg aaaaacaacg atcatgaaag
     8041 ctattttagg actgatccat tactcagatg gaacaatctg tattggtgaa aatgagattt
     8101 ctccctctag tcataaaggg ttggaacaag taggagcatt gatcgaatac ccgggtatct
     8161 atccattctt aacaggctat gatcatctga agttattctc tgaaaccaac gatgtatctg
     8221 ctatcgacac tatcgtgaat cagctcaaga tggaaaagta cattcacaaa aaagcgaaat
     8281 cctactcgtt gggaatgaaa caaaaattgg gaattgctct tgccttactg aaccatccgt
     8341 ctatcgttat tttagatgag ccgatgaacg gtttggatcc acaagcaaca agagatgtgc
     8401 gaaaaatcat taccgacttg gctactcagg gcacctcttt cttgatctcc agtcacttac
     8461 tcagcgagct tgaaaaaatg gtcgatgagc tgatcctgat caatcaagga aagatcatca
     8521 aacaatgtac aatggctgaa ttgaaccaaa cagcgcaaga tttcatcgtt atctctacaa
     8581 caaatgatct agctgctcga acgatcttga cagaagctgg atatactttg gaagatcctg
     8641 ataaaatcaa gcttttaaaa gaaaacgaag aattattagg aaccgtgatc cagctattgt
     8701 ctgcacaaaa tatccatgtg acagacgtcc agcatctgac gaatgatttg gaatcttctc
     8761 tattggaaat tctggattca gtaaaggggg aagaagaaaa atgacattgc ttgtaaaaca
     8821 agaattattt aaattgatca agaaaaagtc aactgctgtt ttatctgttc tattagttgt
     8881 tttgctcata ggaacagcac ttctagccaa aaaatacacg acgatcattg atccagttga
     8941 aatgactgct cagcttttta gtgccacatc ttggattgtc tttatcatga ttgcagctgc
     9001 aagcacgatc atttcgatgg aagcacaata tggtacattg aaaaatctcc tttatcgaaa
     9061 gtattctcga ggagaaatat tagtaagcaa atggatcaca ttagttattt attctgttta
     9121 tttatacctt ttagctatta ttgtcactgt gttgatgaaa ctgattcttt tcccttcgat
     9181 ttccttcacg gagaaggttt ctactggtca aacactgatc caaagcttgt tcacttatac
     9241 tttgggtagt tatatcggtt tatggctgat tttaagttta gtgttgatga ttgcttgctt
     9301 tatcaatagt tccggtgcat ccatctcagc aggaatcgtc ttttattttg cttcgtcaat
     9361 catatctggt atccttattg cactcatcca aaaatgggag tggatcaaat ggaatccgat
     9421 cagtatgttg aatctgcaaa accaaattgg aaacgaagag atcatgaagc aattgactca
     9481 tctttctact aatcaaatgc tattcggtaa tttagcttac atcgttttgt tcttagcatt
     9541 aggatatctc gtatttaagc gaaaaaatgt atgatgactc atcaaaaaag aggctgtgaa
     9601 agagacgttc agccttattg ccgattggct gtctcttaaa caccgtttat tctgaaaaag
     9661 gagctgtgac aacatttgtg tcacagctcc tttcctagta tgtttttgaa taaacgacag
     9721 gctcacaacc tctctttata cttcttttat acttctatac gtgaagcatc ccagtggcaa
     9781 ataaaaccat tgcaatcact ccgaccatcg tcacacctat aagtaaaatc ttatctaagt
     9841 ggatatgttg tacaggctcg ttttgctcct tacgtgcttt gaggtaaaaa taaatgcctg
     9901 gcaagaaaag aacaagaaca agcattactt cattaaaggc tacgactagc atagcccata
     9961 cttgaaaggc acttgctaaa agccctacta aaaattggac ccattctttc cgctgataag
    10021 aaagtttcat ttggtacaat cctaagaaaa gccacgtgaa gaaaatagct gctgtaccaa
    10081 gtgtgtaagc aaagttataa gcactgtcag tgaataataa tgaaagtaaa aagacattcg
    10141 tacataacgt cgtcaatacg atagcataag ttggtgcccc atttttgttg agttttcccc
    10201 atgctttagg caaaagtccg tcttcagcca tgtttcccat tgtttcaatc ggtaagatcg
    10261 tccatgagag ccaaacacca actaaagaaa tgatcaaacc gccgttgatc acgactgctc
    10321 cccatttacc aaccatcatt tcaaacacat agcccatagc aggctgcgcc ttgatcgttt
    10381 gcagctgatt catcgtcatt gtcccatatg gaagcatgga aaccaagacg taaataataa
    10441 tcaagccgaa tatccctaga atcgttgctt tcccaacatc tgattgtttt tttgctcgtg
    10501 aacctacgac agaggctcct tcaataccaa caaataccca aagcatcacc atgatgcaac
    10561 tcaatacttg actggaaaac gggatcggct gtccattcgc attcaatata atgtcgctag
    10621 aaaagttatc aatgaattgt tggatcgaaa acgtgctgat agctactaca ataaataaaa
    10681 ataatggcac taatttacag aatgtgacga tagcattgac gaaactagca ttttcgactc
    10741 cccgattcac tagccatgca tatccccata aaaagactgt actcatcacg atcgatgcca
    10801 gattttgccc accttcaaat actgggaaga aatatcctaa tgcgctcatc aacaatgttg
    10861 caaaagctac gttgcctaac cagcatgtga gccagtaacc ccaaccgctg ataaaaccag
    10921 cgaaacggcc aaaaccttct tctgcgtaac taaagatccc gccttttaaa tctggacgtt
    10981 ttttattgat attattgatc gacaaggaga gcatcaacat tgctgttcct acgagtaccc
    11041 aactgaaaat agctgggccg ccagccgatc cggagatgtc cgtcataata ccaaatacgc
    11101 cacctccaat cgctgaacca attactaagg cagcaagtgg aattaaacca attccttttt
    11161 tctgttgctc tgtatccatg taagcatcct ccaaaataaa accgctttta tcaaaaagta
    11221 taacaaacct tttttatttt tacttaatta ataaaaactt taatagaaat ataattctac
    11281 cggctttttt ctcattatac aagcaaagcg cctagtccct ttccaaatta caccaccaaa
    11341 aaacttaaaa aagatgctat actaaaagga aagaattgga ggatgatcca tgaacatttt
    11401 atatatatcg atttcaggaa atacgcgtgc ctttgccaaa catctagcag aatatgctga
    11461 aaaaatgcat gcagaagatc ctgtcaatcc tgaagttact ttaaaagaaa tccatgaaaa
    11521 tagtgatttt acgaaagaaa cagaaccatt ttttactttc gttcctactt atttagacgg
    11581 cggaaatggt ttagataacg gtgatacaga aatcttgacc gaaacgatgc gtgaatatct
    11641 ggaacatgaa gacaatcata aactttgtct tggtgtagtc ggtagcggaa ataaaaactt
    11701 caataatcag tattgtctaa cagccaaaca atatgcacaa acatttggct ttcctttctt
    11761 ggcagattat gaattacggg gaacaccatc tgatgtgaca cgaatttatc agattttagc
    11821 agaaaacaat aaataataaa aaagaagaag ctgaaaaata gatttcagtt tcttctttcg
    11881 tttctattgt ttctatcata ttaagctttg acatccatca caggtgcttt tgcttttgct
    11941 ttacctgttt tttccaagac aaagtttttt acacgatcca tattggttac caagacgatc
    12001 atggatgttt ctttgcctgc tgctttgatc gcttctaagt cagcttctgc tacaagcgta
    12061 tcaggtgtca cttgctgccc ttctgttact ttcacatcaa atggcgtacc gcctaagtca
    12121 actgtgttga ttcccatatg aagcaagatt tctaaaccat ttggcgttgt gatcccaata
    12181 gcgtgtttcg ttgggaagac agagctgact accccagtaa ctggagaata gatatgtccg
    12241 ttttctggtt ctacaaagta gccttcaccc atcatctttt gtgcaaaaac tggatcactt
    12301 gctttatcta aagaaacaac tgttccgtca gcaactgatg agaggatagt cacactttca
    12361 gctgaagttt gaggtactac tttttcaggc acttcattta ctgtggctgt ttcagtcgct
    12421 aattcttctt tttctaaacg gtctttagga ataccgaaga agaatgtagc aacgaagcca
    12481 ccagcataag ctgccaataa tccaaggatg tagcctaacc atttaccgtc agagatcaat
    12541 gggatcaaag cggctcctga aggtccaata gcgatagccc cgacatttcc gatcattccg
    12601 atcactgccc cgccgatacc tccaccgata caagcagtaa taaatgggcg tcctagaggt
    12661 aatgttactc cgtaaatcaa tggttcgccg attcctagga tcccgactgg taaagctcct
    12721 ttgatcattt ctgttaattc tttatctttt ttgcagcgaa tccataatgc caatgctgca
    12781 cccacttgtc ctgcaccagc catcgcaaga attggaagca atagcgtacg accagtttca
    12841 tcaatcattt gcacatggat tggagtcaaa atttgatgca gtccgaacat aaccatcggc
    12901 aagaataatg tgcctagaac gaagccggca aatgctccac caacgccaag tacccagttg
    12961 atcccaccga ccatgccatc agaaatgaaa cctgctaaag gcatgatgaa gaaaatttca
    13021 atcagaccga tggcaatcaa tgaaagagtt ggtgtaacga tgatatctac cgcatcaggt
    13081 actactttat gcagtttttt ctcaacgatt gacaatagcc aaacagcgaa gatgacacct
    13141 aggatcccac cttgtccagc tgcaagagct tcaccagtaa ataagttttt cagtggtgct
    13201 tccggattca tccctgtcag catcacaacg gccccgataa ctccaccaag agttggtgtt
    13261 gcaccaaaaa cttgtgcagc attgatacct gtatagataa ctaggtagct aaacatcccg
    13321 tttttcaaga tgttcatcac atcgatatat tgttgccatg ttgctgcatc aagtgttccg
    13381 gctgtgacta agtttgctaa aactgcggca atccctgcca cgatcccagt accgacaaat
    13441 gcaggaatca ttggcacaaa gatattagaa atgtctttta ataccgattt gattttagat
    13501 ggtttttgtt tcgatttttg tgccgctttc atttcttgtg cccgttcgtt tacacggtct
    13561 tttccagatg ctgatgaatt tgctgtagct gtacttacag aagaaagttt ttctcctaat
    13621 ttcacgcctg ccaaatcaac catttgctgt gctactttgt tcactttccc aggtccgatg
    13681 atgacttgaa gctgttcatc ttctactaca ccaagcactc ctggaatcgc ttttaattca
    13741 gagacattta caagatcatc attgatgatc ttcatacgca cacgagtcat gcagtggaca
    13801 atgctttcta cattgcccat gccgcctgcc cctttataaa tttgttttgc cagttcttcc
    13861 aaagtcagtt cgttttttgc catggtcttt tccccctcat aaggtccctt ttacaaatcc
    13921 gtttgcttca gctaattttg cttgagcttc ctctttatca ctatttgtca aaatcatgac
    13981 gatagccagc ttaacatttt gatctgcttc ttcaaagtac ttttcagctg tttcgtaatc
    14041 agcttctgtc gcttgcatga tgattcgttt tgagcgttcg attagttttt cgtttgttgg
    14101 tttgacatcg accatcaagt tattgaatac tttacctata ccaatcatac tgatagtaga
    14161 aatcatattc aagataagtt tttgtgctgt tcctgacttc aatcgagtag agcctgtcaa
    14221 aaattctgga cctgcatcga cttcgattgg gaaatccgcg tgtttactga tttcggcttg
    14281 tttattgcaa gaaatcgttc ctgtgacagc accgatcgat tttgcgtaat ctaatccacc
    14341 gatcacatat ggtgtacgac cgctagctgc gataccaata actatatcat tttttgtcaa
    14401 attcagcttg attagatctt cttgccctag ctcataagaa tcttcggccc cttcgacagc
    14461 tacagtcatt gcttcttctc caccagcaat tagacctatg accatttccg gttctacacc
    14521 gaatgtcggt acgcattcag cagcatctaa cacacctagt cttccacttg ttccggctcc
    14581 catataaatc agacgtccac cttttttaaa ggactcaatc gtgttagcaa tcactggttc
    14641 gatacttgtc agttcttttt caaccgcagc ggccactttc tgatcttctt tgttcattag
    14701 ttgaacggct tgagaaatac tcatctcatc taatccaaaa gtttcttggt ttctgcgttc
    14761 cgttgttagg ttctctaaat tgattttgct catttttatc ttccttcttt tcttataaat
    14821 tgatagttca taccagcttt gatttggttg atcaatggta gctcttcttt gataacttta
    14881 gctactacat tcactttttc atccgctggc aaatcatatt tggttaattg gatctcaccc
    14941 atatagcgca aatacttttc gttatctaaa gtaatagacc ctttcatacg cgtagctgta
    15001 tttcttgctg ggataggcgg aatctctcga aaacgtgcat ctacgcttcg tatgacatct
    15061 cttgcatcgt cttgccgatt cgtatgcttc cctaatatat attcgtaaaa ttcttcatct
    15121 acaggttccg tatggagcaa gactgtctgt tctttttgga aagaagcaaa ttgctcctga
    15181 acgttttctg acagacctgc atctccgatg taaacaatat ccgtgttact tgctaataga
    15241 tctagagcgc ctgcaagagg atggatccct cgatgttctt ccaaagttgg caatccttga
    15301 tatagtgggc ctctcaactc tgtatctcct ggtacaaaac cttggacaag gagaccttga
    15361 attttgagcc attgattttt tttctgatac cattctttgt ccagccctgt ttcgggacgt
    15421 ggataataat tatgccaagc ttcaatctgt gagaaatcag cttctgcttc tttcaattca
    15481 tcgatatctt taggcgtgat cgtgctagca ttcaaactga ttttcaattg atgtgaccag
    15541 tcggcaatct gctgattgga aatatgataa tccattctta aacctgttac accaattgct
    15601 ttcaaaggcg ttagatcttc taatgaaaaa cccgctcgtt ccaatgcctc tcctgaaata
    15661 tcgaccatca attctagttt attctttttc gcttcgcttc ctagttcgat caatcgcttt
    15721 tgatatgccg aaacatcatc ttctggtata tgcatggaag tgaaaatacc gacaaagcca
    15781 ttggatgcca tttggcggat atactgtttc ttctcttctg acaaagaatc gttcataaat
    15841 attgaaaagc caaacatatt atccctcttt ttctgtatcc gtcttcattt ctatgactag
    15901 agtatatatc taaagaaaca aaatttcaat acttttatta aaacaattaa atttcatttc
    15961 taaaggttga gtttatatta tcaaaagaat tgtcataacc taaaaaaggc actgctaagc
    16021 aaaagcagtg ccttgaaata ttttatttaa ataacacaaa aacataatta ctcataagaa
    16081 accaattctg tattatctac catgaatgta aagaacccct cattaggcat cggatgaaaa
    16141 taagcattga tcactcttat caaggcatta tggcaaacta acagatagac attttcttcg
    16201 tcttcgatgc attctttcaa taaaggaacg atccgtgcat acacatctaa gactgactcc
    16261 ccatttggga atcgtacagc gaacgctaaa cgtgcttttt gaaagttctc atctttgctt
    16321 ggcagtccat cataatcccc aaaatccatt tctaccaatc gttcatcaac ggtcagcggc
    16381 aagctgagac gatcagcaac tgcttgtgct gtatctcttg ctcgttgaag aggggaatgg
    16441 atgattttcg tgattggaac aggcaaatct actacctttt ctgctagttt ctgtgcctgc
    16501 atctgtcctt tttcagtcag cggcacatct gcccgtccgc aaactaatcc ttgtgcgttc
    16561 caagttgttt ctccgtgtct cgttacataa agcatgtgat tctctccttc gttggcaaag
    16621 ttccccttaa ccataccttg ttgttcttga gattacaagg gttagattct ctcaagagaa
    16681 ataatctcag tagatacttt atccaggaag gtttgatcat gttccactag taacatggca
    16741 ggtttcacgt tcaagatcag ttgttctaat tgttcttgat tgaagacatc caaataattc
    16801 aatggttcat cccatgtata tagttcagct ggctgtgata aagatttagc caattccact
    16861 tttttccgtt ggcccatact catctgctcg atcttgttat gaaaaacatc tctttccatc
    16921 ccaagctttc ggaggttgtt caaaaatgct tggtagtcta cttggttttt ctctgcaaat
    16981 tccgccaacg ttcctcgatt gtcttcataa ttttggcttg cataactaat gctcagatgt
    17041 tttggctggt atttttctcc tataaccttg ccgttgaatg cccccagaag ataatggata
    17101 atggatgact ttcctgcacc gttaggacct gaaatcgcca cccgctgatg aggctcgatt
    17161 gtaaaatgaa ttggctcgaa taacagattt tcatacccta attgaagatc ttctacgctt
    17221 aaaagtcgct tatggtgaga cgcttggcta ttcatcgtca aagaatcgat atattcgata
    17281 tcttttaata gtttttcttt ctcgctgatc tgggtctcca tccgattcac gattgctttg
    17341 gatcgtttca tcgtccgtgc agcatcagca cccactgctc ctttattcac tcgtctagat
    17401 tcagtatcga tgaatccgac ttgtttcttt gttttatctc cttctcggga acgagaccat
    17461 tcggcttttt cagctgctgt tttctttagc ctactgactt cttttttcaa tttttcattt
    17521 tgagccattt caaattcatc acgaagtttt ttctgttctt catagataga gaaattccct
    17581 tgataaagtt ccagttgact tttttcgatt gctaaaacat ggtccactac ttcatcgata
    17641 aatccccggt catggctgac cacgatgaag ccttgttttt tctttttcaa ataagccgct
    17701 acttgttttc taccagagat atccaaatga ttcgttggtt catcgattaa cgggaaatga
    17761 gtgtcatcca caaataaaag tgccagtagg acttttgtct tctctccccc cgatagtgtg
    17821 ctgaattctc tccataagat ttcaggatct gtttgcatca attggagctc tctttcgatt
    17881 tcccatatct caaaatccgt aatatcattt aacacgtaat aggttaaacg ttctttatct
    17941 tttgtctgtt gcgggaaata ggcaaattct tgctgatgga ttacttgccc ttgataaggt
    18001 agtttgtttt gtagaatatt cagtaaagtt gtctttcctc gaccgtttcg tccgataagt
    18061 cctagtttcc attgtgtgtc aaaatttaga tttgcttgtt caaataataa tgtgccttgg
    18121 ctgtcgtagc cgaatgtcag attttttatt tcgattttag acattttcca tcacctcgta
    18181 aaaaaagacc agtcctattt tcagaactgg ctaaagagga tacaagggtt ggatacacac
    18241 aaaaagaccc atacatcgaa aaaaccaagc caatcccgaa aatctgcaca ctgcttcctt
    18301 gtctccacaa ggtacagtct gaatgcagct ttcatcaatc gacttaattt ttcaatgcac
    18361 ggatccctca ctttgtccta tatttgaaat tacgatagca taaagaaaat gattttgtca
    18421 actacttcgg gaggatggtg aaaaatctgc taagtgtctg tcctaagatt tttgtttttt
    18481 ctaatgtttg cctgtgttcc attgcttctt ctaaacctat tggacccaaa tgaatactta
    18541 agacaattgg gagaaaatca gaaagtcctt ctagctcttg gtctctactt ccgcaaatag
    18601 cgattattgg ttttcgatat ttttttgcaa gcactgctac accgtatgga acttttccgt
    18661 ggatcgtttg ctgatcgatc cgcccttctc ctgtaatgat gacatctgct tgttcgatct
    18721 ttttttccaa tccagtgatt tggctgacta aatcgaaacc agaaaccatc ttcgctccca
    18781 acaaaaaaag ggctccacca ataccgcctg ctgctccact tcctggaata tcatctaaat
    18841 ccacctccca gaaatctttt atttgctgag caatctttcc tgcttgttta tctaagaaag
    18901 ctagcgtcgt atctattcct cctttttgtc ttccaaattg ccaagcagct ccttgttgac
    18961 ctgtatatgg attggtaaca tctgcagcga taatcaattt tactttagaa acaagaacgt
    19021 ttcttcgatc aaaatgaagt tttttagtag ataataaagg atttccttct gtgtaccctt
    19081 ctaaagaagc acccaaggat tggagtaatc ctagaccacc atcgctacac ccgcttcctc
    19141 ctaaagtgac aataatttgt tctacttctt gaagcagtgc atctttaata agttctccta
    19201 aggcataact ggaagcaagt cggatagttt gatccgttgg tttatcaagt agatctaacc
    19261 ccaatgcttg tgcagattcg atgactgcgg tgttttttcc ttgccaagtt gtcaataaat
    19321 agctgatttt tcgctgacgg aataagagat ccatcccatc aatggtacgc catgttcccc
    19381 tgagcgcgta atagattgct tctgcagtat tttctccgcc atctgcaatc ggcacattga
    19441 tttttcttcc tttacgatct tcccagccat ttagaactgc ctgatttagt tcaaatgaag
    19501 aagcacttcc tttaaatgaa tcaattgccg ccaaaatatc catctgtatc cctcactttc
    19561 ttcttaagta agacactttt tttcattttt ttcaaacaaa acaatgctat tttcttccat
    19621 ttttctatat actaaaaggg aactcattga ataaaggaga gaaaaaacat gaaaatcgca
    19681 atagctgggg ccggagcaat gggcagccga atcggattga tgctacatca aagcggaaat
    19741 gaggtcctct tgatcgatcg ttggcctgct cacattgaag ccattcgtac aaatgggttg
    19801 attgctgact ttaacggtaa agaagtggtc gcaaaactgc caatctattc accagaagaa
    19861 atcatcgaaa gcaacgaaca cgtggacttg atcgtagcat taacaaaagc caatcaatta
    19921 gatgatatgt tttgttcgat ccaatccatt attactgaca atacttatgt tttgtgttta
    19981 ctaaatggat taggtcatga agatgtactg gaaaaatatg tgccaaagaa aaatatctta
    20041 tttgggatca cgatgtggac agctggtcta gctggtcccg gaaaagtcac attgttaggt
    20101 gatggagaaa tcgaactaga gaacttggaa ccagaaggcg aagcatttac aaaaaaagtt
    20161 gtagaagtct ttcaagaagc aaatttaaat ccgatctata gccataacgt tcgttattcc
    20221 atttggcgaa aagcttgtgt aaatggaaca ttgaatggtt tatgcacgat tttggattgt
    20281 aatattgctg aactaggcgc gcaaaaagcg gcagagagca tggttcgaac aatcgtatct
    20341 gaatttgctt ctatcgcagc aaaagaagga atcatactag atcaagaaga agtgtaccaa
    20401 catattgctt ctacttatga tcctgacaac atcgggttgc attacccatc tatgtaccaa
    20461 gacctgatca aaaaccatcg tttgactgaa atcgactaca tcaatggtgc catttggcga
    20521 aaaggacaaa aatatgatat tgctacacca tattgtgcct ttttgaccca attagtccat
    20581 gcaaaagaag gaatccttgg cgcagaataa aaggctctct gatgagaatc agctgaatca
    20641 gcagctggtt ctcttttttt aagcccaata aaagatcaaa aagaaaacac aactctcatg
    20701 atgccataag aattgtgctt gtttgtttca gtacataatc tcttcaaaat gtaggttttt
    20761 tatttgtttt caacagagga gaggtcatat tcgtattgct cataaatagt ggaatcgtta
    20821 gtgataaatc gttttgccca attttctgca tcataaaatt ccaatagctc tgataggatt
    20881 ggcttaaatg atgtatgcag aaattccggt aattcatcta aatcacgttc tcgaagcaaa
    20941 aaaatatttt caggacgata aaaatgataa tgagcaatcg cttgattatc cgtcactagt
    21001 ttcttttgaa aatacatgga ttcaaatgtc cgcaaagtca ctccttgctg accctcccgc
    21061 aacagttcca gaatcccgcg cgattcccct gtttttttca ggtactcttc ataagtaaga
    21121 tatccaggtt gttcattccc tcgatgtgga agaatgaaat agttggtcgt aacatctctt
    21181 tttataaatt cctgcttata gctttctgct cgttcttttc tcccattatt cgttgcacca
    21241 aaaaatagat ccgtctttgg ttcgctagaa gaaaaattca tatgtttcga ataaaatgaa
    21301 ctattatgtt tcagcccaag ttcttttgct tccaaaaaat caaaatgata aatctcatcg
    21361 attgccggtt catcttgtgc ctgcttcagc atcgcctcgt gttctgcttt gaagtgattc
    21421 caaaaaaata acacaatttt tgcattggta aatgggcgca cgcgtcgagc catctccata
    21481 ttaaatccat aatctaaaaa aacgatcagc tgataatttg ccaactgttg tctagctgat
    21541 ttaatgaatt ccgactgtag taaatctttt ccggaccaaa catctaaaga gcggatggaa
    21601 ggcaaaaaat aaagtgattt attttttgca actagcagta cgtcattttt gttcatcttt
    21661 tccgcctcac tttctctgtc actttttcct atgatagcct gtttaaatag taaaaagcca
    21721 gtaaaacgct tcctatattt gtatgaaaat ttaacatttg tatgaaaata tgatgaaata
    21781 aatcattctt ctattaaaat tcgcctaaaa gttttctgaa tagttgtaat tgtctgaaaa
    21841 tttgttatca ttagtcattg ttaaatattg ctatttattc ttaatataaa ttttgattgt
    21901 gaatttaaaa gaaagaggtc atttatggaa gataaaaaat tgaaaaaaca acttagctcc
    21961 agacatatca ccatgttagc tttaggtgga gcaatcggtg caggtctatt taaaggaagt
    22021 ggcgaagcga ttgggatcgc cggcccttct gtattgattg cttttttgat tggcgggctg
    22081 attttatata tcgtgatgaa aggtctggga aaaatcgttt taagcggtgg cgacacgcat
    22141 cacggattat ctggtttgat acgcccttat ctaggtgctc attctgctga ttttactgat
    22201 tgggtctact ggtctatgtg gattatcaat atcatcgctg aagctgttgc agctgcttcc
    22261 tttttgcagt tgtggttccc gcacattcca gcctgggtat ttgtttttat gttggctgtt
    22321 ttaactacga tcatcaatct ttattcggta cggttattcg cagaaacaga atattggctg
    22381 gcttttgcta aaatcagtgt cattatctta ctaatcattt ttgctactta tcttgtcggt
    22441 cagcaaatgt tgggcacagg cgttttccct acccttcagc aattgactga ccatggtggg
    22501 tttactcctc atggtatgaa gggaatcatc agttctttgc ttgtagttat ctattcttac
    22561 ggcggttctg aactgattgc tatcacggta agcgaagcag atgatcctaa acgtgcgatt
    22621 cctaaagcca tcaaaggtgt catgggaaga atcatttcct tttacatcat tcctttgttt
    22681 ttgcttttga ttctttttcc ttggaatact ttagcaggca cgaatgtcag tccttttgtg
    22741 atggtatttg aaaaaatgaa tatcccattt gcagcggata tcgtcaattt tgttattgtc
    22801 cttgctttgt tctcatctat caattcgggt gtgtatgcat cttcaagaat tttgttcttc
    22861 cgtttgaagg atcgaaaagg ttcctctaga aaactagctg ttttaaacaa gcatcaagta
    22921 ccgcaacgtg ctgttttatt ttgtaccagt gttctttatc ttggtgtagc tctttcttat
    22981 tttgtcggtg acaaattatt tggctatctg gcaggttccc tttcgtatac agtattattg
    23041 atctggatca ttatcagtgc ggcatccttt gtactggcac taagaaaagg aacattatgg
    23101 gataaaggaa tcagcttttt tgcattagct gtcttaggat tgattttcct tggtatcctg
    23161 ttcacgaact ccattggggt aactgtattg actggcctgc tttacctgtt catttatttc
    23221 agttatcaaa aaaagaatga tgcgttcgta ttgacgaatg aatgaaatcg atagaaaatt
    23281 ttattttatt tatgtggaat agatggaact attgaagaaa ggagttgtga caaaagtctt
    23341 gttgcaactc ctttttccga ataaacagtc tcatgacctc ttggtaaacg gtgttcaaaa
    23401 accctctgtg caaaataatt gattgttctc catgctcatg acatgataga agaaaggaat
    23461 gaaaaaaagg agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgatcggtgt
    23521 ttcaacggta gttatgtttg gtatgatgta cttgaatgtc tatgcgctcg atcatatctt
    23581 cttcagtcgt acacgagtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat
    23641 gctgttgttc atgtggaaaa tgtatgaaaa caaaaagata aatgttatga tcttagccgc
    23701 tagtcttctt gtttttgccg gttccttgtt tatggtacga agccaaacta ctgtcaacga
    23761 cacagcttgg atgaaggcca tgattcctca tcattctatc gctatcctga caagtaaacg
    23821 agctgattta aaagatcctg aagtaaaaaa attagcggaa gaaatcatcc aggcacaaga
    23881 agaagagatc gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccgtcca
    23941 aataaaaaaa gaggatgttc cagaagtgat cagcttcaag aaataagaag aagctacttc
    24001 tggaacaccg tgaataaggg gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    24061 caaacaaaaa tagcttctcc tatttttcgt ttggttaggc ttattaccgc agatgcaagc
    24121 ttttgaacac cgtttattcg taaaagggat tgtgacaaaa aaagtcttgt cacaatccct
    24181 ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc ggtttcacaa
    24241 atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca ggagaaagca
    24301 aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta cttgctacga
    24361 aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca tcttctagcg
    24421 ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta aatgcattac
    24481 caggcagaat aacagatagg aattgttcac caataaaaat atttactccg atacttgtca
    24541 tcaatgttgt aaaaatcaat tttggtgtgt tcgtcatctt tcttgatact cgttccatca
    24601 cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt agaataatca
    24661 atgacacagt aggcatcata ctttcgattc ctccgcgact aagcagtgaa tcgatttgtt
    24721 ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc gttaaggaag
    24781 tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac aaaatcgtca
    24841 aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga atcagtgacc
    24901 agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata gatgaaagac
    24961 ttgcggcttt acttgtgtgc cctaaaatca tgaataaaaa gaaagaaaca acaaatgccg
    25021 gaacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca acaatagctg
    25081 ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg gcacctgaaa
    25141 caatagctcc aacaaccagc gctggattta ggcctagtgt tgtcccaata ccgaaaaatg
    25201 caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct acgattgcac
    25261 acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac ccaatgacca
    25321 ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaacct actaaaataa
    25381 aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg tgcagccaat
    25441 ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct gctaagatcg
    25501 tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa acaataacca
    25561 ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg ataatctctc
    25621 cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc cgccgcaatt
    25681 catccgctat tcctccttta taaaaataaa aagacctgtt ttaaactaag gacgaatgac
    25741 tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact tttattcaaa
    25801 tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc gaccaccgac
    25861 tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtatg aagtttacct
    25921 tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg aaaattattt
    25981 ttataacttt cacacacaag tttatttttt actagaaagt agcaccctct tgtttttttc
    26041 ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc tctttcaaca
    26101 gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca aggcctttgt
    26161 cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc tcagagattg
    26221 ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca gaagaaccga
    26281 gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct tttgcatgct
    26341 ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca ttttggaaca
    26401 atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata ttttccactt
    26461 tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa cgtccagcag
    26521 cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca tggatattga
    26581 catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg atcaatgctt
    26641 ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca ccgtaaaatt
    26701 tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga aaagctggat
    26761 ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag ctgcctttag
    26821 ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt tctccaccag
    26881 tttcatcaat aaattgctcc actatgctgg cggctaatac ggagtaagta ccaaacaaat
    26941 tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa aaggcaattg
    27001 tgggtccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt ccagctactt
    27061 ctttttctac ccaaaaccct tctttttcta attgtttaat caacgctgct gaggaataaa
    27121 actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct tgatattctg
    27181 gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt gtcataaaaa
    27241 attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat gcaggcacgc
    27301 ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga taagcgtcta
    27361 ctattttttg atacgtttta tttttttcat cttcttttct tgcaacgatg atattcacat
    27421 aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca ggattaaatc
    27481 cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac aaagcacgtg
    27541 ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg gtaatatcag
    27601 aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca gtttgcaata
    27661 acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt gctccgtctt
    27721 tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca ttgacagtat
    27781 ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa aagaattgat
    27841 gttggaaaga attcaaatca atcgatccat ctgctaaagc cgcatttggt tgattgtaat
    27901 ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct ttcacgttgt
    27961 cccatacatc tgtatcttct ccaataattc ctagttttac ggtagtttct tttttgtcag
    28021 ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca aatgtaatga
    28081 ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt aattttttta
    28141 atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa taatgtagcc
    28201 acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag attccctaat
    28261 ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat gatagtcaac
    28321 gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa aataataccg
    28381 attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac ttctagcagt
    28441 gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg cactaaagct
    28501 gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa aagagaaagc
    28561 aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat ttcaaatagc
    28621 agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc taagatgatt
    28681 ccgatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg cttcgtcgct
    28741 tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa gaaatcagtc
    28801 attttatctt cctccttcga tcactttgat acgactatct aattcgtttt tttgtaaaat
    28861 atttattttt acaccagatt tgatcaaata atccaatgct ttttgccgct gtttggtttc
    28921 tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact ctacattgcc
    28981 atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta gaggttcgtt
    29041 cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct gatcggcaaa
    29101 agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg ttcgaataaa
    29161 atctttggtc aattcttctt caggattgct gaagatctgg atgctactac ctttttcaat
    29221 gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa cttgcatctc
    29281 atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta acaatgcaag
    29341 gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata ataatacctt
    29401 aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc ccgacagttg
    29461 tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt cattcacttt
    29521 ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa cgttgtcaaa
    29581 aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg cctttctttc
    29641 ttttcgcaat tctttgggag agagctgact caaattcgtc tgattgacaa tgacttctcc
    29701 tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc ctgcacctga
    29761 gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag aatctactgc
    29821 ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt caatcattaa
    29881 aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt ttcttgagga
    29941 cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac tcctcttcaa
    30001 gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca tctatgctcg
    30061 ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct cagctaccga
    30121 agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata atattcaaaa
    30181 aaaaatcctt ttactaacat aaactatgtc agtaaaagga cgacgtatcg cggtaccacc
    30241 ttttttcgga agtttccttc cctcaagccc aacatctcaa aaagagagat tggcgttcgt
    30301 tttaacggtc gaacagttcc gaatttgcct acttatcgac aaattattct ccaaggccat
    30361 tttcagcttt tcttacttga ctcttctcac cagccagagc ctctctgcaa agtttccaaa
    30421 cttactttcc ttttcaacga aatcgatatt ttgttgttgg gattaatcta catgaggaaa
    30481 actaaaaagt caagcacgaa attcaaatta ttttttctat atttattttt ctgttttttt
    30541 atctaacatt tcaataacag ttcgaagatc ttttccttca gcaagaagtt tcaatttttc
    30601 cttttcttcg acggtataat ttcggacaaa actggaatca ggtatcaaaa caacgcctaa
    30661 tcctgctcgt gaagcagctg ttgctcctac taaagaatct tccactgcaa aggctgaact
    30721 agcttctaat cctgttcgtt ccaaagctgt cagataagga atcggtgaag gcttgttctc
    30781 cgacacttcg tctccgaatg taaacgtgtc aaagtaatca gctaatttaa agtgatccaa
    30841 gatatctgtt gctcttttcg taacagtggt cgtagcaatg cctagtttca tatgacgttc
    30901 ttttaagtct gccaatattt cttttgcata tggttttaag tggatggctc cgcttgtcag
    30961 ctgttgataa aaatattctt cacgcttcgc tcggacttcc tgtacttttt cagggctacc
    31021 tgctgctttc actaaaatat caaaactttg tttccagttt tttccgcccc aagcgtcaac
    31081 gatttctttt gggatatgga tatcaaattg ctgaaatccc caaagccagc catcacgata
    31141 cgttttttct gtgtcaacta acaaaccatc taaatcaaat attgcacctt tcatctatac
    31201 attaatcctt tccaaaacaa tacacatagt ttagcacgac tggtccaaaa ataacagaag
    31261 caaagaacca gccttctcgt ttataagagt tcttggaatc gatggatata gattttcttc
    31321 acagctgtca caagcgccag ataagcgatg actgtagcaa ataaccataa ccagtaattg
    31381 ccaggaagtg gcatcaagcc taattcagca ccaaaacttg taaaaggaag gacagaaccg
    31441 acaataattc ctaatgtagt gataacaaac atggcaaatg ttacgttgct ttggataaat
    31501 ggtactttcg gtgtacgcag tgcatggagc actaaggttt gtgtccatag tgattcgaca
    31561 aaccatcctg catggaataa tgcgatgaaa atcacttgct gtgaactatc caatgtatgg
    31621 aaacttccgc caactacagc aggacaaata acaaaataca tcaacaagta agtagtaata
    31681 tcaaatatcg aacttgttgg gccaaagtaa accatgaatt tcccaatact agatgcattc
    31741 catttttttg gctcgtccaa atattcttta tccatccgat cccatggcaa ggaaatgcag
    31801 gaaacatcat agattagatt caaaaacaga agttgtaaag gcagcattgg taaaaatggc
    31861 aggaacatac ttgcaatcag cacggaaaac atattgccaa aattagaact tgctgtagcc
    31921 ttgatatatt tcatgatatt cccaaaagtt tctcgtccag aaagaaggcc tctttccaaa
    31981 atcgtcaaat ctttttctaa aaggatcacg tctgcagatt ctttcgcaat atccacagct
    32041 gtatctacag aaataccgat atcagccact ttcattgcag gagcgtcatt gataccatct
    32101 cctaaaaatc cgacagtatg accattttta cgtaaagctg tcgtcaaacg tgctttttgc
    32161 tgaggattca attttacgaa tacttcatgg tcttcagcta cttgtgctaa ttcatgatca
    32221 ctcatttccg agattttctc accggtaacc aattcattga tctctagacc tacttgacgg
    32281 cacactgaac gtgtaactaa ttcgttgtcc ccagtcagaa cttttacagc tacaccatgt
    32341 tctttcagag ctttcaacgc ttgtttcgtt gtttcttttg gtggatcaag gaaagtaaga
    32401 taaccaatca aaaccatgtc tgactcatct ttgactgaaa attctccaac gacgcttgga
    32461 ttggtctttt gtgcgacacc aatcactcgt aagccatctt cattaagtga ctgtactttt
    32521 gcaagtacgg cttcttttcg ttcttttgtt aatggtgtaa cagtaccgcc aagatcaata
    32581 aatttagaaa tgttcagcat ttcttcaatc gcgccttttg tgatcatttg tgttttacca
    32641 gctggatcag caaccacaac actcatacga cgacgttcaa aatcaaaagg aatttcatcc
    32701 actttttgat aattgatctt atctgtatct aaagtttctg ttgcttcatc aatgatagcc
    32761 acatctaaca aatttttcag ccctgtttga tagtagctat ttagatacgc atggcgcaaa
    32821 acacgatcat cttcatttcc ttcacaatcc atatgatatt caagaatgat tttatcttgt
    32881 gtcaatgtcc ccgttttatc cgtgcataac acatcgattg caccaaagtt ttggatggca
    32941 ttcaaatttt tgatcactgt tccttttttg gccatcacac ttgctccttt gaccaaattc
    33001 gtcgtaacga tcattggaag catttcaggt gttagaccaa ctgctacaga tagtccaaaa
    33061 agaaaagctt ctagccaatc cccttttgta agcccattga tgacgataac tgctggagcc
    33121 atcaatgaca taaatttgat cagtagcatg gatgttttat ggatgcctaa ttcaaagctt
    33181 gattgaattg gtttttcaga tagcgtttct gctacatgac caaatagtgt ttcatttcca
    33241 acagaaacaa tgattccttc cgcacttcca cttatgacat tacttcccat aaagacaaga
    33301 ttttcgtaac ttgtttcgct ttgctgatcg tcttcacata ctttcgcatg cttttctact
    33361 ggatagcttt cccctgtcaa tgctgcttgg gaaatgaata aatcctttgc ggacaataaa
    33421 cgcatatccg ctggtatcat atcccctgct gaaagccgaa caagatctcc acagacgatt
    33481 tcttccatag gaatctctgt gtactttcca ttacgtttta cagctgccgt tactttcaca
    33541 agtgatttca gtttttcagc cgcttgattg gaacgtacgg actgaatcaa cgtcattgtc
    33601 ccgctgacga tgaccatagt gaagataatg gctacaccga aaagatcttt atctccagga
    33661 gctgctaata catattccgt gatgaatgaa ataattccta atgcgatcaa cactaatgta
    33721 aatggcgtga tgtatgcttt caatatttct acgatgaatg gtgttttttt gccatatgaa
    33781 atcgcatttt caccgtaatt ttctcttgaa cgttcgattt gttcttctgt caatccattt
    33841 gctgatgcgt ggaatagttc aaataattct tgtttcgttt ttccagcaaa agctgcatag
    33901 attttttgtg tatctttctt tttttccatc tcaatctctc ctttgtgtcc aaaagacagc
    33961 tgttctcgct gcttttggtc tttagctatt catcggatcg atagagaaaa aactgaaagg
    34021 ggctgagaac agatagataa tagccttggc ctttcctcta gatccttgtt tttcgaatga
    34081 ctgtcatcca tttgttctca tctcctttac taagtaattt taattcatga cttccaatca
    34141 tttttcgaat agttattttc ccaattagac cacctccttt ttatttttca ccgatgggga
    34201 tttgcggcaa caaaaaaacc tctcgccaaa tactcagcga aaggtttgaa aaagcatatt
    34261 aaaaaaagct tctcagatct catcgttgag ttttgacact gtacaacgta aaaagcagat
    34321 acctgctttt agctacctta tgaaaagcct tatctcgaca attcctgttc tacccattgg
    34381 cgtctctcga cgtttttggg cagtagccta tgtttgtata ggagcctcac ctaacaaatc
    34441 ttattcggtt ttccttcgtt aatataacaa ctaaaaaaga ggatgtcaaa tcaattttcc
    34501 atgtttttca tacttttttt aaaatacaca cgttatattc ctgtctcacg cggttttatt
    34561 tgtctcattt tccacctccc gctataatag aaatatagta ggaaacgagg tgctgttatg
    34621 gaaagaacac ttgttattat caagccagac ggcgtgagac gccatttagt cggaagcatc
    34681 attcaacgtt ttgaagcaaa gggactggcc attgctgaaa tgaagtttga aactatgact
    34741 cctgaattag caaaagaaca ttatcagcac ttgactgagc gcagtttttt tgatgaactg
    34801 atcgattaca tgacttccgg tcctgtcgtt tatcttgtgc tggtcggcga ggaagtgatc
    34861 gatatcgtcc gtaagatggt tggggcaaca aaagctgtcg atgctgttcc aggtacgatc
    34921 cgaggagact acgcgctgcc ggggactgaa aacatcattc acgcttctga ttcccgtgat
    34981 gctgcggtaa aagagatcgc ccgctttttc ccgccattcg atataaacaa accgtctgaa
    35041 aaagcggcga agtgatacaa attctaaact gctggtctag ttgctgggtt cagcaatggc
    35101 cagcagtttt ttctctaagg acctccgttg attctttcct aacatatatt cgagcactgt
    35161 gaagaattct tggtagtctt tcgtcttttt ttcccctaaa gcagcagaaa tcaatctttg
    35221 ataataatct gccatcaatg tttcatagat cactgtactt ctttctttat gtgctaagct
    35281 ccgtttcata tcttcattca cactacgtgc ctttttcaac cgaccatttt ctatataaaa
    35341 cgaagtcagg ttcattaaaa aagtaaagag atactgctca tgattgttca actgtgctaa
    35401 tcgtcgcatt ctttttttga ttttcaaata attgttctca atgaaccgat cactgaatat
    35461 ccaaggaaaa tcagctagaa tagatagttc aaattgacca tagtctggta tctgcatcaa
    35521 gtattcttca atgattcggc attcataacg taaaaattca aattctgtct cagatacttc
    35581 tgttttttcg accatgtgaa gactcaaaac caaataatac agatcttctg ttttcttaaa
    35641 atgcctacgg ttattgctga tctctttata aggatcaaag ctgtcttctt gtacccgatc
    35701 tagcattcgt ctttttttct ttaactttat tggttcatcc agctggtttc gcatccattc
    35761 atattctgca agtgtcatgt tcattcgctc taaaaatgat ctcaatgtta caaatgacat
    35821 ttttttcact gaatttgtct caatcccgac tagagaagtc ttagaacaga ttccttccgc
    35881 taattgggac tgtgtcaact tcttgttgac tcgaagtttc ttgatcaatt caccatcata
    35941 cataatagtt ctccttttta atttaaattt ttccacattc aataaataga tacgttaaaa
    36001 aggaaaaata cacgaaaaaa ataaaaaaat gtttttttca taaaaaatac caaccttcaa
    36061 gcattagaat gttgtctaac tactgaaggt tggtttgatt gtttattgat tatctttttg
    36121 ctgttcaacg tctgttcttg ttactggata taagttggtt gttgttttat tgccattttt
    36181 tgaaaagaca cttgtcgaat gttcgccttt ttgcttttcg atggctatgt tacgttctgc
    36241 ttcattttta tagtcatatt ttttcggatc gatcgtttca aatccgtttg gcacataaaa
    36301 acgcaagaga ttttcttgat tcagcttatc tgaaagactt aaagcagatt tgactttttc
    36361 ctgatctttg gaaatttcct cgtcgattcc tgctgctttc gtatcgatga tttctcctgt
    36421 ttggttattg taagcttttc ctcctaagat ggtgtatttg ggtgtcacga agttcccatt
    36481 tcgaaaagcc actacttgat catgctgagg agataataaa tccgtaccaa aatggagata
    36541 gtctttatca tcgattccca agagatgaag taatgtcggc aaaacatcga tttctccacc
    36601 gtattcgtga ttgactgacc ctttagtata accaggtata tgaatcatta atggcacacg
    36661 ctgcatttgt gcgttgtcaa attcattcca tgtatctggg tcttttccaa gagcacttgc
    36721 taagtcttta ttatctgtat ttgagatgcc aaaatgatcc ccataaatca caaagatcga
    36781 attttggtaa atagcggatt ttttcaggta cgtaaaaaat tgttccaatg actgatccaa
    36841 ataatgtgcc gttcgaacat agttatctac tgtgctattt ccagtgttca aagatggaaa
    36901 atcgaaattc ttatcatccg tataataagg cgtgtgattg gttacggaaa ggaatttcgt
    36961 gtagaacggc tgttgtagat gttcaagata ttgggcagat tcactgaata aatctttatc
    37021 taatattcca taacctagcg tttcatctga ttcatcaaaa taagatcgat caaagaaatt
    37081 gtcataacct aagtttttat atacatgatc tctattccaa aaactagcta cattcccatg
    37141 gaaaacagcg cttgtatagc cttgcttttg tccaaggatc gctggtgcgg cttgaaagac
    37201 attatctgac ccaagttctg tgaataatga gccttgaggt aaaccaaatg tgccagtttc
    37261 caacatattt tcagcatcac ttgtctttcc ctgtcctact tcatgaaaaa aattatcaaa
    37321 gctgatcgtt gcttgattct ggaaaatact atttaaaaac ggtgtgactt cttgtccgtc
    37381 taccttcata ttaatcaaaa actgctggaa actttctaaa tggagaacga tcacattttt
    37441 ccctttagcg atcccaaatg tttcgggatt tggctctgca taatgtttct ttgtataatc
    37501 taaaacttca tcaatcccat tactgcttgc atgcgcgcga acactgctag tcattcctgt
    37561 tttgattcca tcataaatag tatacgcatc gattcctaga tatttgacaa tatatgaacg
    37621 gtcaaatgtt cgctgcagca attgtggacg gttggcttcg ctcagcgcta gatttcctga
    37681 aaaaataagc cctgaaagac aggtcacagc gatagccatc ggtttgctga caggttgact
    37741 tttgataggt attttcttga tcgtcaacca aaccagtatc ccaatgaacg tagcaatatc
    37801 cagccagtag aggacatcat ggggtttcat caaagaaaag gagcttcctg ataacccttg
    37861 cgacactttc gaaaatccca atacagattt gactgtaatg aaatctgtga attcccgata
    37921 aaaaataatg ttcaagtaca acaaaagcgt gtttaaaata tcaatgatca aaagaatggc
    37981 taatgctggc tttggctttt taatatacaa agaaaggcca aaaaacaata aggtagttgc
    38041 aatcgggttg atccacaaga taaagtactg gatcgtacct tccacaccta acgaaaaatc
    38101 tgcatagtaa gcaataatcg tcttcatcca gaaaaagaaa acagctgtca aaacgattgc
    38161 taaacgattt tggcacaatt ttttaagttg tgtcacgtat atcacttctc tctattcaca
    38221 tttttcctta ttttgctcct gaaaaatgaa aattccctaa aaaagttgtt atcttaagat
    38281 ttttttattc tttctaaaga ttattccgtg cacttttcac agcataaaac cgctgtgata
    38341 taagcgattg aaacagtaag gtgataaaag tcttgtcgca gctcctgttt agttgatgca
    38401 ggacagcttt ttcacaactt cttctttaaa cggtgttctc ctgccaactc ctcggccaca
    38461 agtcacaata tttataaaac atgagaagct gttttttgaa attgttcctt gtggctcaga
    38521 gttaaacggc aagctcaaga cctcttgata cacggtgttc aatcagctga ccttcggtat
    38581 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    38641 gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc ataggattga tattgtcctt
    38701 gtgatgactc attcgtaata attgaggctt gattttcttc acttcccgtt atcgtttgtc
    38761 cactgccaga atctgaagga cttgttcctg tcgactcgtt tttttgagaa gagacagttg
    38821 ttttcttgac ttgttcattt gtctttttcc attccgctaa acgatcggcg accacttttt
    38881 tgtctacttt ttcagaataa gcggtgatca cttttccatt tttcaaacgg gctactttgt
    38941 cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc tttaaattga tattgtctga
    39001 gagaaatcgc actaagtacg tcatcgatat taataaattg attttcttct tttccttttg
    39061 gcaaatagat gtccaattcg cctttttcgt aattggcagt tattttatac tccgcccacc
    39121 aataagttga gaattctttt ttgaaattat ctactgattc tttgcttgct acgatttttt
    39181 ctgtttcttt ctgagcaaga tctgctgtca tttttcctga aaatgctgcg gataaaataa
    39241 gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg tctttttttc ctcatgcttt
    39301 cctccactcc tatttaattt tgactattct attatataca aaaaatgaaa tagaaagaca
    39361 aaaaagttga aaaagatcgt aaataattga acttcttttt cacaaaatgg taagaatgga
    39421 gaatttcacg catttgctct caactattct ttcttaagcc tcaaatccgt ttttatctga
    39481 tacgtctttg aaccagtgac ccgatttttt gattgttctt tttccatctt gtgctaagtc
    39541 tactgaaata aagccatatc gattcttata tgcattggtc catgaccagt tatccataca
    39601 tgtccacata tgatagccta aacaattggc accttcttga attgcttgat ggacatattt
    39661 cagatgagat tggacaaatt cgatccgata atcatcgtgg atcatgccat cttctttgat
    39721 aaatcgtgct tcgttttcta cacccatacc gttttcagaa ataaagcagt cgatatttcc
    39781 ataatgatct cgtacattga tcaaaatatc atagattcct tgttcataga tctcccatcc
    39841 gcgataagga ttcattttac gaccaggcat ttcataattg tcgaaataat cctcaggcat
    39901 tggaccgttt ttagtatcga ttggtgtttc ttttgctttt acccggcgtg gctggtaata
    39961 attgatacct aaaagatcta ctgtattttc tttgatgacc gtcaaatcct ctggatggat
    40021 cacaggcatg agatcaagtt cttttactat ctcaatcaat tcacttggaa actcgccttt
    40081 tacagctgga tcaaggaatg aacgattgaa gaacgcatct gctatttgcg ctgctttaac
    40141 atcttcaggg tttgattcgt ctcttggata gcttggtgtc agattcaaga tgataccaat
    40201 aacaccacct tgctccattt catggtaaga tttgatggct aacgctgagg ccaacgcttc
    40261 atgatagcca acttggatcg cttttttcat atctgactct tctggataat gccatcgata
    40321 taaataacct gcttcgactg gaacgattgg ttcattatga gtaaaccatt tttttacttt
    40381 cgaaccgaac aattcaaaac aacttttggc atatttttca taggcttcaa ccgtttctcg
    40441 gttcaaccat ccgccttttt cttgcagata catcggcata tcgaaatgat acagattcac
    40501 aaagggttcg ataccgtttt caatcaactc atcaaaataa cgatgataga aacgaacggc
    40561 ttcttcgttg attgttccag attcatcagg tatcaagcgg ctccattgga tagatgttcg
    40621 aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc tcttgatact tcgtataaac
    40681 ttgtgaagtt ttttcaggtc ctacttggtc aaagaacttt tgcggttctt ttttgtacca
    40741 ataatcaaaa atgttctctc cttttccatc acctgaaatc cttccttctg tttgtgggcc
    40801 acttgctgca gaaccccacc aaaaatttgc tggaaattga tattttttca tcaaagcacc
    40861 tctttttctt ttttagttcg ttttagttga ttccatgtat gatattttcc atcacaatta
    40921 ctttttcatt ttcttcctct tcttttttga ttcgtttcaa cagctgttct gcggcttgtt
    40981 ccccgatttt atctgttggt ggtgtaatcg tgattttcgg aaggatgctc aaatcgtttt
    41041 tatccaaata atcataatga ctaaacgcaa tatccttccc gattctgata ccttcttgat
    41101 tgaaacattc gatagcaccg atcgacatat tataattgct gacaaaaatc gctgttactc
    41161 ctttttctaa taattctttt gccccataat agccactttt tctagaatag tctcctgtaa
    41221 agacctctaa ttggatcgat ggatcatttt gtaccgcttc ttttgctcct gctaaacgtt
    41281 ctcttgctac gtagtctgtt tgagtggcag caataaatcc gattttttta tgtccttgtt
    41341 caccatgatg agcgatcact tttgctacac tttctcgatc attcactaat attgtatcaa
    41401 tacctgctgg tccttctggg caattcaatg cgataactgg aatactcatt tttgtgagca
    41461 tttcaaatcc agaccactct tcttcggata agaagacaat cagcccatcg atcacatgct
    41521 tcatcaggta ttcaattttt tgttcaattt tttctggctg atcggcaaac ccgcttaata
    41581 ataagctata cccattttct tcagctactc tttcgatccc tgagacaact tccgacccaa
    41641 aacggctgga aatcccgttt atcaaaagtc caatagagaa gcttcgatta ttcttcaacc
    41701 ctttagcaat gatgttttct ttatagtcca acgctgaaat cgcttctgct atttttttca
    41761 tgttcttttc cttcagttgc tgaccattca agtaacggga aactgttccc actgaaacac
    41821 cagccatctt agccacgtca cggatcgatg ccatacattc tcactcctgc cagttacatt
    41881 tgatttctct ttcttgttgt tcgattatga tgaccgcttt ctttgcatag tgttgcttgt
    41941 catcaatatc catataacta aagtcttcag tagagcaact tcctctcact attaattata
    42001 cttaaacaag tatttgaacc ggttcatttt taatatagca tttttttaaa agattgcaac
    42061 acttttttaa aacgctttcc taaaatggcg aattttttgc ctttttaaaa ttttattcta
    42121 aaatttactc tatttgtggg tgttttgtgc gtttttctct tccatccgtt tgaagtttta
    42181 ctttccaatg gtataatttc tttatcctat caaatggggg aagtattttg aagaaattaa
    42241 tcgtactatt tattttgtct gcgggacttt tgacattgac tggctgtaat ttgtttggcg
    42301 gctctgacca atcctcggat gaaacaaccg attcttctgt cttaaaagcg gaaaaagcag
    42361 atatcactaa cagtgtatat acgctaaaag tacgtaaaga tatggattta tccgcgggac
    42421 agttgacatt tacagataaa aaaatggaat ggacacgcac gtatcagaca caagaaactg
    42481 attcttctga atcatctgaa gaaaaaacag tgctgacaga catcaagatt actaccaaag
    42541 atgacgaata tattatttca ggaaaagaaa ataaaaaaga agcaaccatc acatttacca
    42601 aaatcggtaa ttaccgtttg aaggatgagg atggcaacat ctacagtcta tagtgccgtc
    42661 tgttggatct tcttttgttt ctccccttct tttctgctat agtaaagaag caagatgatt
    42721 gtaaaggaga cgaaatggat gatcgatagt cctgattatt gtacatgtaa taacaacaaa
    42781 aatatccata cagaatttaa tgaccaagga agcttgagca tatgcgacaa ctgtcacaaa
    42841 ctagtcaaag attcatttaa aacatttgaa tcttatcctg ttcaaaatta tgtaaaaagt
    42901 agaagaagat aaacaaatcc aagcaaaact cactatggct gatttttatg aacttcaaac
    42961 tcagcttctt cctttgatca agcttcatca gtaaaacaaa cagtggatca tttcagttta
    43021 caaatcaaag agtaaagatt tatttatttc aaatatttga atataaaata accaaacgat
    43081 agaaaggctt attctacatc acgtagtaat ttttctttcc cgtcgtttgg ttttttattt
    43141 ttagcctaat tcttgacctt ttgcatgctg gttatccgta aaatattttc cagcaggctt
    43201 tccttccaat tcagctagtt tttcttggat ctgatggatc accttttttg catcttctgg
    43261 attttctaca aaatcgaatt tatccccatc cacttgtatt ttaggacata catcaaaatc
    43321 ttcataccat tgattatagc gggtgttcaa cgtttcataa taggtatata acgtctcatc
    43381 gctttctagc tgttcatagt cacgcccacg ttttttgata cgttctagca tcgtgtccaa
    43441 agaaactttg atatggacca tcaaatcagg ccgttttttt ggagcaacat catctaactc
    43501 gtttagcatc gtatctaata agctatcgta ctgctgtact tcgatatccg ttacccgacc
    43561 taaatcagcg tttagatgga acaacaggct atcttcatag atggatcggt ctagcacatt
    43621 gtcatcgttc actaaagcat ttttcattgc taaaaatcgc ttgttcaaaa agaagatttg
    43681 caataaaaaa gcgtactgct caggatttga ataaaagagc ggcaatactt cgttatcttc
    43741 gacattttca taaaatggtt tagaatcaat ctcttttgca agcatatccg tcaaactgct
    43801 cttacctgca ccaatcgttc ctgaaatcaa aatcactgac atacaaccct tcctcttcta
    43861 taagtactcg cctacgtaag tttcaacagg caatgtttca aaatcatatt cacgtacagc
    43921 ttggtctgat tttaaatacg tatggagact ttgtgtaatc atcaagttcg taggtaccgt
    43981 ctcttcttgt acaatgatca tcggtttttt caacatagtt gccacaccta attcgtaagc
    44041 cgttcctgga tcgattgttt gatgctcaaa gtcaaggata gcaacaacaa attctgcatt
    44101 tgtcagttct tccatatctt tttcgtatac ttcctgcgcc catccagcgc tgaatagttc
    44161 ataattgctt tcttggtgat gacgtggaga gtagaaactt gtgactgttt tgttttcctc
    44221 caacgctttt tcgatacgac ttactcgatc gatttgctcc tctgaaaaaa atggtcctgc
    44281 taaatatatt tgactcatta ttttgcctcc ttcaataata actgattttt aatagatact
    44341 gctcgtaatt cattgaccag ttccaatgga ttgttggaaa agattacttg atccaaccat
    44401 tttttatcca taaaatcctc ttttgcaaaa gtttctaata attgttgcaa gccgctgtaa
    44461 taaccgccaa tattcaatat tccgattggc ttgtcgggcg tcagaccgat tgctatccaa
    44521 gaaagaagtt gtgagaattc ctccaatgta cctagacctc cagggaaaac gaggacagca
    44581 tctccctttt caaataataa tacctttctt tcatcgatcg tttctgtagg aataaatgta
    44641 gtaacatctt ttccaggcaa ttcagtttca aaaagcccat tcggatagat acctgtgact
    44701 tttccgttat tttccagtac tgttttacta atcactccca taatcccgga gtatgaacca
    44761 ccgtaaacca gttcgatttc ttcttgtgcc atgtattttc ctaacgtttg cgcaataaat
    44821 ttgtaacttt ctttattacc aaaacgggaa ccgcaaaaaa cagtaagttt cataaaaaaa
    44881 cactccctaa ctcaaaagtc tatcttcatt ctacacgtgt ttttttaaaa taaaagacta
    44941 gattttgtag ttttttagtg gtatatagga tagacaccac tatatatagt atttagaaaa
    45001 aaacattttt cagctatttt atagataaaa caaaaataaa taacgtgttt tcatcgatgt
    45061 gaaatgactt acttatagaa gatactggga tttcgtccta tatgccaata acgtgtatta
    45121 ttttaaacaa caaatacttg tttcttttat taacgaaaaa atcattttgt tctcgtgtta
    45181 tgtttcactg ataaatgatg tttctctaaa taaaaaagcc gacgaactaa acgatcaaaa
    45241 tttgatcatt tttgttcatc agcttctcct aaaaatcttt ttgttaacga taaatagctg
    45301 gatttgtaaa aatatcactt gaatcgtcac tgctggaaga aaattcagtg ataaccgcac
    45361 ctgttgcgcc tgcctggaac tagtgtttga tattgggctc gaacgtgtac tgatctctag
    45421 catgaagaat aatttctttt tttactgtat aataactttc tttccttttt ggaatagtac
    45481 aggaaagttt ttttgtttcc tttccttcga cataaggtat accagaccct ttcgacaacg
    45541 aaaggttctc atttttcctt catcgtcatt tcaaggaggg tgccgatgct ctggacagtt
    45601 tcgatcgctc ctaaaccaaa atctgtatat tcgattcttt ctaactctga ttctttcata
    45661 ccattcctgc ctcaaggtac atctattgta cttttttctt gtaatccact ctgcctctcc
    45721 taactaattg tcaaatcatc ccaagatatg tcttcttcct ctttttcttc ttggatgatt
    45781 tctgcattcg gatctactgg ttttttcaat aataaaatgg ttattcctgt gacaaaagaa
    45841 ccagctaaca atgcaccaat gaatgcccat ggtctggtca tcgtagcgac tgcaaacatt
    45901 cccgatgccg gaatacggct atctgcgccc caaaacatgc ttaatccgcc acctactgtc
    45961 ccaccgactc ccgttgctat gacattgcgt gccaagtcgt tcaatacgat agggaaacat
    46021 ccctctgtga tctgacagat ccccatagga aaagcggtct tcaatgtatc gatttcttga
    46081 cgattgagta tatttttacg aatgattttc cctaagaaat aagcgatcgt caagccgaat
    46141 ggggttacca tcgaagctaa aatcaataca gtgattggtt catagattcc ttctgaaaat
    46201 cgtgccacac ccccttatcc agaataaatg gtaatccaga aacagccgtg tatctgcggt
    46261 aataagccta accaaacgaa aaatatgaga agctattttt gtttggctgt tcttattact
    46321 tgatgcaggg cagctttttc acaacctctt tttttattta tgtttcataa tcaatatggt
    46381 aaggatgcag ctccgtatgg tagaccgcct ccgaatattc aatcatttcc ccaatttgcg
    46441 tagacgattt ccgtatccgt ttgatgccga tctgtgcgtc tgttttcaga attccttgtt
    46501 cttcttctgt taaaaatact gccgagaaat catcagaaaa tgagtcaata gtatatcctt
    46561 ttttcgtcag caaacgatac aaagattctt tgccaaattc ttctctgctg aattgcatca
    46621 tttcttgtgg aagataatga acaaaataaa tataaggctg attgttcaaa taatataagc
    46681 gcttaaaaca aacagcttgc tcaccgaaaa aggaaaacaa aggatcttcc ttctttatat
    46741 ggaccaattg caaatccagc gtttctttcc ggacttcata tcgggagttc tccaagattt
    46801 gcgtaaagct tgccgctttg gataatcgat tgtaaggacg attgcttaga accgtcgtcc
    46861 cacgaccact tttctttgcg acatattcat ctgatgccag cagttcgatt gcctttcgga
    46921 cagtgatttt gctgacttga aacagttctt ctaattcact ttctgtcggc aacatcgaac
    46981 cgactggata ttttcctgag aaaatatctt ctttaatttt atctgcgact tccaagtata
    47041 gtacacgtgt ccttttcata acgtcaccct ttgctttact attactaaaa gaatagcaca
    47101 taaaaaataa aaaaagaaca caaatcacat gtgagaagtg tgttcttttt cattcagctg
    47161 ctttaattac aagtttacgc catttgaggc aattacttct ttataccaat caaaagattt
    47221 tttctttgat cgattcagtg tcccatttcc ttcatcgtct agatccacat agataaagcc
    47281 gtaacgttta ctcatttctc ctgttgatgc actgacaaga tcgatacatc cccaaggcgt
    47341 atagcccatc aaatctacac cgtctgctac tgcattagcc atcgcttcga tatgacgacg
    47401 taaataatcg atccgataat catcaataat cgtgccatcc tcttccatat gatcaatggc
    47461 tccaagaccg ttttcaacaa tgaataatgg tttctggtaa cgattgtata attcattcaa
    47521 tgcgattctc agcccttctg gatcgatctg ccagccccat tcacttgcct caagaaacgg
    47581 attttttact cctcccagca agttcccttc tgaagttgct gcttgtggat cagtctcatt
    47641 gattgccgta gacatataat aactaaatcc gatgtagtcc actggatatt cttttagcaa
    47701 ctggaagtct ttttccgttt gctctaattt ttccggatcg actccatatt ttttatgggt
    47761 acgcgctgtg tatgcagggt attctccacg tacttggaca tccgtgcaga aaaaattgaa
    47821 ttcttggttt tggatcattg ttgctgcctg attgactgga ttggcatcga tgctgtaagt
    47881 tgttgcatag ataatcatgc agccgatttg gatatccgaa cgcaattcgt ggccgatttt
    47941 tacggctttg ctacttgcaa cgaattgatt atgccatgct tggaaaatat tttggtactc
    48001 tcctgctcca ttgcttttta ctaatccttg acttaaagct ggaaagtgaa aggccgaatt
    48061 gatttcattg aaagtcatcc aatatttgac tttactgctg tatctctcta atactgtctg
    48121 agcaaatcgt tcatagaagt cgatcagttt tcgatttttc cagccaccgt attcttttgc
    48181 caaatgaaga ggcatttcgt aatgagaaat cgtgatcaca ggttcaatat catattttaa
    48241 gcactcatca atcagctgat cataaaattc taatcccgct tcgttaggag taccttcgtc
    48301 tccatttgga aaaattcgtg tccaggcaat cgaaaaacga taacatttga atcccatttc
    48361 cgcaaacaag gcaagatctt ctttgaaacg atcgtaatga tcgattcctc gatgattcgg
    48421 gtaaatatat ttttcttgat caatcgtcca gtcaaattct tcactgccga taatcgcaaa
    48481 gcgctgctta cctccaggca tagcatctgc aacggatagt ccttttccgt ctcgatcata
    48541 agccccttct aattgatttg gcagcagttg ctccacccca taaaaatttt tctgaaaaac
    48601 gtgattgcat cctgatttcc tccttatttt acaattgcca gaacatcttc gtttgcaata
    48661 atctcttttt ggtctaattc aagtatatcg gcaaatgcat cagtattcgt aatgacaact
    48721 ggagtgatta cgctatagcc agctgctcta attgcttcga tgtcaaaacg aatcaataaa
    48781 tctcctgctt tgacgagatc cccttgtttg actaagatct caaagccatt cccatttaat
    48841 tctactgtat ccatcccgat atgaatcaaa atctccgctc cgtcagtcgt tgtgatccct
    48901 acagcatgtc cagttggaaa aatagtcgtg atctctccgt ctgcaggtgc aactagttct
    48961 cctacttctg gatcaatagc gatacctttt cccatcacgc cagaagaaaa aacttggtct
    49021 ggtacttcac tcaatggcag tactttaccc gttaaaggac tttttaaggt atgccgtgct
    49081 gaagtaatcg gttctcctgc attcgcatgt ttgttttcta attgattgtc ttgtgtttgt
    49141 tcgtcaaatc ctaaaatcaa tgtacctacg aatgcaagaa caaaagcaat tcctgtagct
    49201 attactgcta ctgtcacatt tgactctaca ccatccaccg tattaatgaa agtcggaatc
    49261 gtcaataagc tgaccaaact gctggagaaa gcttttactc cggaaaatcc gataatagct
    49321 ccaccaatac ctccagaaat acaagcggca atgaatggtt tcttcaaagg taatgtcaca
    49381 ccatacacag ttggttcagt gattccaaat aacgaagtca ctgtagaaga aatccctaat
    49441 gctcgaagtt tcgtatcttt tgttcgcaat gctacagcta aagcagcccc accttgtgcc
    49501 aagatggctg gaagaagcat tggcatcaat acatcaaacc catattgttc gatattcaaa
    49561 aacatgatcg gtacgaatcc ccaatgcatg ccgaacatca cgaatacttg ccataaactt
    49621 cccatgatta gacctgctac gattggacta aatccataaa tcgagttgaa gagaccgcct
    49681 aaagcattac cggcaaccgt cccgattggt cctaaagcaa gaaatgttaa tggaaccatc
    49741 actactaaaa cgacaagcgg aactaaaatc atttgcagaa attgcggaat cacttttttt
    49801 acgaatggct ctaatttact ttgaacccat acggctagaa tgattggtat gacagaagaa
    49861 gtataaccag atggtgaaag aatcactggg atcccaaaga aactgatagc ttctcccgca
    49921 ccagcaactg ctgtgatagc tggatacaca agtgccatag caattgctac tgctaaaaac
    49981 tggttggctt tgaacttttt agctgctgta aaagcaagca tgacaggtaa gaaggtaaag
    50041 acaccatctg ctgcagcaaa caatatttga taagtaccgc tatcagctgt cagccagccc
    50101 atcaccgttg ccaatgataa gaatcctttc aataccccgg cggctgccat cgcccctaga
    50161 aaaggtgtaa atatactaga gataatatcg atcagacgat tcaaaatatt tttggactct
    50221 tcttttccat cctccgaaac tgcaagacct tcctcatcca cgatcgattg ataaacatct
    50281 gctacattac tgccaatcac tacttgatac tgaccgccac tttgtacgac ttggatcacg
    50341 tccgggtctt cttttaactt ttgcgtatct gctaaagatt catcttttaa tctgaatcgc
    50401 aaccgcgtag cacaatgtac taaacttttg acattctttt gtcctcctac cgcttcccat
    50461 acacgacgac caactgcttg attatccatt gttttttcct tctttctttt ttatttaaaa
    50521 aataaaaacc cagattgaaa aaaacagtca caaacattcg tgaacctatt ttttcaatcc
    50581 aggttttgcc tgccatacag taacaatcct tatgattgga tgcttttttt ctcacttact
    50641 actctttgaa tatgaatcgt taaataaatc tgctctgcga tccccatttc ctgtttttgc
    50701 gtttgtcgaa gatactcatt gatccgttcg acacaatgaa acgcttttgg atactttcct
    50761 tgaactaatg cgtagagaaa ttcatcttgc tcgtcagatc cttccccttt gagataacgc
    50821 tgggcaaaaa actgcagatg agtaatgata cgctgataat tcaaagattc ttcatcgaac
    50881 acgatgccga agaatttact gatgatactc agtatatctc ttaccattgt ggtagcggtc
    50941 atcgtcactt gcatgtcttc gtttccttgt tggctattca caaaatgaaa ggcaataaaa
    51001 ccggcttcat cctcagaaag ttccacaccc gtcttttgtt tcacgaacaa aagagcctct
    51061 ttcgctgctt gatattcttt cggataaaat ttttttgttt caaataataa tggattaggc
    51121 agttggatat tttcttttgc tcgtgtgatc gcataatgaa gatgatcggt caatgtcaga
    51181 taaatattag gcgaaaattc aacttttagt ttatcttcag ccagttcgac tacttgtttg
    51241 acccattcga tctcctctgc cggaatatca gccatcagct gctggaattg gtttttagca
    51301 aaagaatctc ttaaaacaaa ttctttttgg accgcttctg gcgaaatctc gtccccaatc
    51361 tttttttgaa aagctagtcc ttttcccata caaacgactt cttccccgaa tccatttttc
    51421 gaaatgacga cattgttatt caaaatttta tcaattttca ttttgcttcg ccctctcaag
    51481 aaaaataaaa aaacctagaa ttcgcctact gtttcttagc tgaattctgg ttttgcctgc
    51541 cgtacagtaa caatccattt cttattcaaa atcatcatac catcgaattt ttatttatgc
    51601 aagccttttc atataaaaaa taaaaaaact ggaacacaag tctatctaga aaacaaccaa
    51661 atcagagatg cacctctttg cgtttctctt tttttcagca aattggtttt tccttatcga
    51721 ttcatatcct ttggctgttt ttaatctgta acgacttatg tcccagtatc ctaaaatgtt
    51781 tttgtctcta gattgaaagc agatctcata tcatctgtcg catcttttat cgatgtaaca
    51841 ctttccagtt ctccttgtac aactagtcgc gtgacggcgt ccatgtcgcc acaagtaatt
    51901 agtgtgacaa tttcttttcc ctcgacttca ttcagtaatt gggtatctgt aggagcaact
    51961 ttttctttaa aaaatgtttt gtatgtatac acattttcta aatctgtcaa atagatcttg
    52021 gcacccatct ctaaattttc tagcggtgta aacagcaatt cagggttcgt tgcacgatgg
    52081 cttgctaagg cataatttcc ttttcccatt tcttgatctg gagataatgt tcctgctccg
    52141 taaagtagtg acgtattatc caagcctttg aaaaccggta aattgattga aactgaaggg
    52201 actgcgatac tagcaatcac tggtagatct gttcctctca tttgcgacct catgacccct
    52261 tctgtcgtca ttggttctac cgcatcaaag tcaaaactga catctttatc gttattcttt
    52321 ttcagatctt cttttgttac attcgctata gcatatttat ctcctgtctc tctgacaaaa
    52381 taatccttga tctgttcatt gaaaatcaaa gctagtccta ctaataacaa gaggaacaag
    52441 aggatattga ctagccatct ttttgctttt cctttttttt tcattttctc tccctccaga
    52501 ctcattttac tgtttttctt ttgctctttc caacagccga atgacacatt tctacaactc
    52561 tgtgtatttt tttcgtacac ctgcgctttt ttctacagga tatttcaaat tatttttgat
    52621 caatttttct tcaatgatct catctagatc caggtgaagg ttgtctgcca tcatgtatga
    52681 atagatcaat acatctgcca gttcttcttt gattcgttct aattgtgttt cttttacttc
    52741 ttccggcgtt ttccattgaa aaagttctaa caattcagat gcttccaaag aaatagagat
    52801 agccaaatct ttttcgttat gaaattgtcg ccaattacgt tcatctctaa actggttgac
    52861 tttttccata ctattcattt gcttgccttc ttccaatcac ttcttacttg attaatcata
    52921 ccattttttt acataaaaaa tagatgatgc ttttaaaaaa actcctgttt tcttttattt
    52981 aaaataaatg tcatagaaaa tcaataattt aggtagccac catgtgtatg cagtagcgtg
    53041 tcttcttccc ttgaggcttt ttgtttttcg atacgttctt cttcccaaac agacaacgct
    53101 actagaatct ctcttaatga ttttccttct tcggtgagcg agtactctac tttaggcggg
    53161 acttggttat aggcttttcg atggatactt tcatcttgtt ctaactctct taactgctgg
    53221 gtcagcattt tttttgtgat cgtagggatt tgcttgcttc tccacgccta aaataagcga
    53281 tattgctctt ccctttatct ggtgtaagca aagcagttag cattttgacg atcgtgggtt
    53341 ccgcttttca cttcttatct acttagtatc atgaagtata ctttcgtact aatactaagt
    53401 agcggaagtg tcaactactt tgtttaacta catagcaaaa gaaacagaag ggtgacaacg
    53461 gtcatcacgc ttctgtttct tttgaatatg ctgtgttgtt gtctctatct ccgtgtagac
    53521 tttcctcaaa cttatccttt gacagtaagt cagtaggctg atttgctctt tctagatgcc
    53581 agatacattt ctacaaaaaa atagtgattc tgttttgaaa attcgatttt tagttctgca
    53641 ttttcgtaaa catccaacat ttttttcgca ctgtatagac ctaacccgcc atttttttta
    53701 gaggtttttc ctcttttgac catctccgat agcgtcaaat tcgttggatt tgccttgttc
    53761 gctatactaa aacgtgatcc ctctttttct tccagcagat tgatcgtaat cggactctga
    53821 tcggctacac gatgatcgaa tgcgttagaa ataaaaatag ataaacagcg aataaaaaca
    53881 accagatcaa tcgggattgt tttcacttcg acaggaataa ctacttggat cgggattttc
    53941 tccgattctg ctttttctag aaattttaaa aagacacccc tgacagctgg ggatacaata
    54001 tttgttagct gttgtatttg cggtttttca aaaatagctg cagaatgatc ttctaatatt
    54061 tctaaaaatt ccaacgtttc ttttttattt tcctgaagag taatttttaa tgaaaacagt
    54121 agacttttat aatcatgttt gaattcctct agatgatggt aatattcttc atttatttga
    54181 tacagttgaa gcgattcctg atgttgtctt tcttttactt ggaaactgat caacataatg
    54241 gaaaaaaaca aagaaaaaaa actgatgact atcgacaaaa gagatagaag cagataatta
    54301 gatgagcgga agtgaacact tcccaatacc aagtaaatca cgccccagct taataaaata
    54361 caaatacctc caaaatagtg ttcagttgga taagtaaaaa gcaagttgag aaatctcgtc
    54421 tgtttgtcta tactttttac taatagatag aaaataaatg cgataagtag tgcaaaaaaa
    54481 cttgctgttc caagatgtct ctttcctaaa taatccatca gatcaaaaac cagaaaaaag
    54541 ctgagtccag tgatagcaaa aaaaagatta ctgatcaaac agctgataaa caggtttttc
    54601 gtagtaaaat aaaaaagaaa catcaataat aagccaacta ggtaaggaaa gctcacttta
    54661 gggataggaa gtaaaagtgt caccaccatc aaagctatac aaccaaagct gttttttact
    54721 agcagttgtt tcgaaaagaa taaatagata cctaaatcta aaatcaaagt aaaggtcaaa
    54781 taaagtgtca ctgttgcgac catcttattc ctccattgtt ttgtttcaaa atgtacacat
    54841 atttttttaa taggagcctg catatgaaaa agtattttat catagaagat aaccagtttc
    54901 acagcgaatg gatcatcaga gaattggtca atcatcatat cgagaatatc gtgcagctca
    54961 cttctatctc tcaaatcaat cagttgatcc agttgggcac tattgataat cacgatgttt
    55021 tctttatcga tatcgacttg aagcaatcac tcacaggtat tgatgtcgcc gaacaaatac
    55081 gtaaaaaaaa tgcacatagt aatattgttt ttttcaccgc ttatacgaat tttgcagtag
    55141 agatcatcaa tcggaaaatc cttccgattg gatatatcag aaaagacagg aatttatctg
    55201 aacaaattcg tcaagtgcta gaacagatca attggaaaga acagcagatc gtaaatgtcg
    55261 ataaaatctt tattgatcaa aaaggtggaa gtctcgtcct gtatcctcgg gaaattttat
    55321 atattgaaag tatcaaaggt ttgaaaaacc aagttatggt caaaacaact acagaagata
    55381 aattagtgaa tacttcttta aaacaattga agacagagtt agaaaagtat gcttactttt
    55441 tacttttaaa atcttactgt atcaacttat cgcaattgca gaaaattgat tctgctcatt
    55501 atgtgttaga atttttcaac ggtgactcct tactcgttgg tcgaaagatc tttgaaaaga
    55561 caaaggaacg tttccatgac ttccaaaaaa ctgcttcgag ttgatgaata agagctgaga
    55621 cgtaagcata gcagatttca gggagtgggc cttgaatcgg ctccactccc tgaaatcgtt
    55681 gatatgattt tacgcttcct cttctgtagg agcatctgtt aacgaccatg tgaatgttga
    55741 aacgtagttg tctacagcat aattggatac aggaacaaat aattccactg attgtctccc
    55801 ttgttccaca ttctctccta atgaataaat ccatgtgcca atcccttcat ttgctcctgc
    55861 agttactaga tctactgcct gatctgctgg gatttcgatt ccttcagcgc cagttccaga
    55921 aacggtagat ggcattccac tgctattagt tgcgctattt cgaatcacgg cgtttttgaa
    55981 tttcaccttt gaaccagtta gtttattcgt atcagatgtt gtaccaataa attctgttcg
    56041 tttgactgat aatttccaac cggcataatt tccgctttta tccgttactt gtacgaaatt
    56101 ctgtacttgt gtttgtgctc cagtactgtc cgttccgctt tgtaatgcag catatactgt
    56161 ttttgctgta cctaacttga ttgttccaaa atcaagatct ggagcttggt caatcgtcag
    56221 taatccggat gttccctgat ttggttcgtc aggtgtaaaa ggagtatcag gatcatttgg
    56281 atcaacagga ggaactggaa caacgtcttc aggatttgca gcatctggtt tggtcacaga
    56341 aatcgttcct tctgtagtgg ctgagctctt attctcagca aaaacacttt gtgtacataa
    56401 taatagactt ccagctagaa cggtacttaa tgcaattgtt tttttcattt ctttttcctt
    56461 ctttctttta aaataaataa tccagcaaat aagccaataa gaatgactcc aacaagtatc
    56521 agccatcgcc agtcaaatgt ttctggctga ttttttaaat caatatcctt ttcattcaat
    56581 tggtccgctg catcatcagt tatttcaaaa tcggtatgga gattccagcg tttttctttc
    56641 caagcaccct tcacaaccgc ttgataatgt cccggagcta atttttttcc ttctaatggg
    56701 acaagtaaat caaaatttgt attgggtgct acatctattt tttctttttt tattgaaagg
    56761 taaggctctt ttgtttcttt tttgtagatt tcaaccgatg tagtcaagcc gaacatataa
    56821 gaagcatttg gattttgaag attcgcctta atcacatttc ttccatcgct ttgatccgca
    56881 taagcttttt ttaatttcaa atctggggaa gactcttttt cgctatttca aatcaagatt
    56941 gctttcactt gagaaaactg attgacgaca ccaactgtac ttttgttaga aacgttctct
    57001 tttttttctt gaaacgtgat ccctcctgcg accacaccag ccagctcttt ttctggcgct
    57061 ttcagtgaaa gtgtctcagt gaccgcactt tgaggaggaa cagttatttc tcccactgtt
    57121 tttgctaagt ttttcatatc ataacttaat gtttcatcaa atttactttt tgattctcca
    57181 tattcgatca caccgtttga attcgtcgta gcggagtgga tcaatgtctc aactgttact
    57241 gatttatctg ttcggttaaa gaccgtgtag gggatttcct gtgttttccc aggctccatc
    57301 cttacattta tatatgtttt gttcttatca atctgattag ccggtaattc aaaatctacc
    57361 gcaaaattga attcggaggc atggacaggt gtctgccaaa ggatgaatcc aaggagaagg
    57421 atcataagta aagagcagtt gtttcgatga cttttattcc atattcgatt catcaatcat
    57481 cctccttgat ctttattctg tcggcgcatc tgctaatgtc catgttatct ctgctgagta
    57541 attaccagct atctgatttt ctttggttaa gacaagttta aacgcccgac cgttatttaa
    57601 atattctgaa taatctgctt gcacattcgt tgaattttgt cctctgacaa tttccagttc
    57661 ttcttcattc actaattgat actcctctcc tttcttgaaa tataggacat cctgcataga
    57721 aaatcctgca tcatttgtga aaggctgaga taattttatc gttaagatcc acggattttt
    57781 cgtttctcgc tgatcataaa tccataattt ttcctgtata tccatttggc caaatgcttc
    57841 ttgtgtcaaa ccagttgctt tgatctgacc aaaatcgagt ttggaagggg caagaaatga
    57901 gagaccacct tctactacga tcttcgtagc aggtgcaaaa ggcggggcat catgataaac
    57961 aactggcgta tcacttggat tgtgattccc aatttcatcg ttggtacttg gcttgttctg
    58021 cacaccctta gcagtagctt ctcctgcttg gtcgtttaat acaatttcta atacatctcc
    58081 tgcaaaaagt tgattttctg ggatagaaag aacaaattcc cctgtatcat caatagttgt
    58141 ttctgacaaa acagcttgat tttttttcaa tgaaaccaag gctcctgctt cacctgtacc
    58201 tgtgatcgtg cgagaagctg cattgatcaa tgtggtactt aaattagcag gttcaggagg
    58261 aatcacatcg actgtcgttt tggcagagtc cagttctgtc acttcttggc cacctcttac
    58321 ttttttagca gcaacaactt gcacttgatc ctccgttttt aatctctcat cattgggtac
    58381 ttgaacttcg aacaagccgc cttgttcgcc ttctccccat gggttatatc ctgccccttc
    58441 attttcatct gtttgtcctt gcgtgagagc agtaatttct acagatgatt tcgtcgtatc
    58501 tgcgtaagta atacgtaaag tcacttctac ttcgcctgtc caagcatctc ttggctttgc
    58561 ctcgacacct tcgggaacaa cgacatgccc atagattttt ttatctgcat tcgttggcac
    58621 tcttaaggat tcaatcatcg ggagctgatt attggcactg attcgattat aatttttcat
    58681 tccggcacct gtctgagcaa attcatttgt taaacctgca ctagggcttg atacgaaatt
    58741 gcctaagtcg gtcccattga tcgataagtc tgtcatatca gaaaaataat ccgggtcttt
    58801 ttcaaagtta tcgaatgttg cgcctgtttt tcgccataaa gcgatttctg aatgggcgat
    58861 ctttaaagaa gaatctccat ttccttggaa tacccagccg cctatgccat tggtctcgct
    58921 tccaatccgt ttgttttgga aatcaaaata ggtaggagat tctaagtcca cattcaacac
    58981 atccccactg atgatgccgg tcttatcttc ccctgttttc ccgaccatga ctaaataagt
    59041 tttttcacct gccgtaaaat ttaaatcaat atctccagtt gtatctacag ttgctccgga
    59101 atctgcgcgt atatcgatat ttgatttttc tccagtgact gtaaaatcag ctgaacctgg
    59161 actttctaga aaaccagaag cgtcataaaa ttggatcgct tgatttcctt gattgagtct
    59221 gttcacgtaa gatttgccat cacctgtatt tcttaccctc aatgagcctc cattggttac
    59281 tgtcagcttt tgcgtaccat tctcaaaacg aactgcgctg gaacgcccac tctgcttatc
    59341 gatgtcgata actgatccgg ctccttctac gatcaaagaa aggccttttc ctacaaaacg
    59401 catcccattg ttcccgggtt gatcgtcatc tccagccatt ttgaccgaga tttgtccacc
    59461 acttgataca tggatttgac tagaatctcc ttgcaagcga aatccgcccg tagttgctgt
    59521 attgatggtg attttcccac cattcgatac agtgactttc gatcctgaac ctctcatttg
    59581 gatgattccg cgattgttgt cattggtaat attgatcttt gtatttaccg aaaattcgct
    59641 tcccgaacca ctgacttcaa acatgacatt accaggtagc gtatcgactg cctctccttc
    59701 atcgctaacg ccatctgccc gatcataatc aagagagacc tttgaaccgc ttaagatatg
    59761 gattcctggc gctgtttttc cactaccagt ctcatctcct gaatctagaa aaccgtagaa
    59821 tttccctaga tacggtccat aaagttgact accattgatc acattcaatt gatagcttct
    59881 acaaaaatag gctttacccg gagcggcatt cagtccttcc ttcactggtt ggacatccaa
    59941 cacaccggaa acaccatcta atgtgacagt tgcacgagga gcgtaaatca gtcctaattt
    60001 ggacccatca tacaaatcaa gtgtcccggt aaattttatt tctcccgtaa aatgatatct
    60061 gcttccccaa aaatcggtca tataagcaat gataatggca tttccatcga tatttggtgt
    60121 caatccacct ggatgtgcag ctgttc
//
LOCUS       DBGZHO010000009        59345 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.009, whole genome shotgun sequence.
ACCESSION   DBGZHO010000009 DBGZHO010000000
VERSION     DBGZHO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.009"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(159..1469)
                     /locus_tag="ACN3HL_000771"
     CDS             complement(159..1469)
                     /locus_tag="ACN3HL_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HHC8005668.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="ACN3HL_000772"
     CDS             complement(1481..2899)
                     /locus_tag="ACN3HL_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8005669.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="ACN3HL_000773"
     CDS             complement(3139..4707)
                     /locus_tag="ACN3HL_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HHC8005670.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="ACN3HL_000774"
     CDS             complement(4711..5121)
                     /locus_tag="ACN3HL_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HHC8005671.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="ACN3HL_000775"
     CDS             complement(5118..6041)
                     /locus_tag="ACN3HL_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HHC8005672.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="ACN3HL_000776"
     CDS             complement(6038..6916)
                     /locus_tag="ACN3HL_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HHC8005673.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="ACN3HL_000777"
     CDS             complement(6903..8240)
                     /locus_tag="ACN3HL_000777"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HHC8005674.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="ACN3HL_000778"
     CDS             complement(8243..9346)
                     /locus_tag="ACN3HL_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HHC8005675.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="ACN3HL_000779"
     CDS             complement(9420..10928)
                     /locus_tag="ACN3HL_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHC8005676.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="ACN3HL_000780"
     CDS             complement(10894..11586)
                     /locus_tag="ACN3HL_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HHC8005677.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="ACN3HL_000781"
     CDS             complement(11608..12582)
                     /locus_tag="ACN3HL_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005678.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIVAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="ACN3HL_000782"
     CDS             12882..13754
                     /locus_tag="ACN3HL_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005679.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="ACN3HL_000783"
     CDS             complement(14212..16410)
                     /locus_tag="ACN3HL_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005680.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="ACN3HL_000784"
     CDS             16642..17634
                     /locus_tag="ACN3HL_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8005681.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="ACN3HL_000785"
     CDS             17694..19115
                     /locus_tag="ACN3HL_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HHC8005682.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="ACN3HL_000786"
     CDS             19108..20607
                     /locus_tag="ACN3HL_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HHC8005683.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="ACN3HL_000787"
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="ACN3HL_000787"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HHC8005684.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22199..22882
                     /locus_tag="ACN3HL_000788"
     CDS             22199..22882
                     /locus_tag="ACN3HL_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HHC8005685.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="ACN3HL_000789"
     CDS             22884..23720
                     /locus_tag="ACN3HL_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HHC8005686.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="ACN3HL_000790"
     CDS             23731..25485
                     /locus_tag="ACN3HL_000790"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005687.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="ACN3HL_000791"
     CDS             complement(25761..26102)
                     /locus_tag="ACN3HL_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HHC8005688.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="ACN3HL_000792"
     CDS             complement(26170..28341)
                     /locus_tag="ACN3HL_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HHC8005689.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28552..29409
                     /locus_tag="ACN3HL_000793"
     CDS             28552..29409
                     /locus_tag="ACN3HL_000793"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHC8005690.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29480..30337)
                     /locus_tag="ACN3HL_000794"
     CDS             complement(29480..30337)
                     /locus_tag="ACN3HL_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHC8005691.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30322..33024)
                     /locus_tag="ACN3HL_000795"
     CDS             complement(30322..33024)
                     /locus_tag="ACN3HL_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HHC8005692.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33037..34326)
                     /locus_tag="ACN3HL_000796"
     CDS             complement(33037..34326)
                     /locus_tag="ACN3HL_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HHC8005693.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34476..35522
                     /locus_tag="ACN3HL_000797"
     CDS             34476..35522
                     /locus_tag="ACN3HL_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8005694.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35524..37677
                     /locus_tag="ACN3HL_000798"
     CDS             35524..37677
                     /locus_tag="ACN3HL_000798"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HHC8005695.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38150..39601)
                     /locus_tag="ACN3HL_000799"
     CDS             complement(38150..39601)
                     /locus_tag="ACN3HL_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8005696.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39598..41322)
                     /locus_tag="ACN3HL_000800"
     CDS             complement(39598..41322)
                     /locus_tag="ACN3HL_000800"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHC8005697.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41315..41929)
                     /locus_tag="ACN3HL_000801"
     CDS             complement(41315..41929)
                     /locus_tag="ACN3HL_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HHC8005698.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42274..43731)
                     /locus_tag="ACN3HL_000802"
     CDS             complement(42274..43731)
                     /locus_tag="ACN3HL_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8005699.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43772..44692)
                     /locus_tag="ACN3HL_000803"
     CDS             complement(43772..44692)
                     /locus_tag="ACN3HL_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8005700.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44704..45651)
                     /locus_tag="ACN3HL_000804"
     CDS             complement(44704..45651)
                     /locus_tag="ACN3HL_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005701.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46130..46849)
                     /locus_tag="ACN3HL_000805"
     CDS             complement(46130..46849)
                     /locus_tag="ACN3HL_000805"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HHC8005702.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(46898..48544)
                     /locus_tag="ACN3HL_000806"
     CDS             complement(46898..48544)
                     /locus_tag="ACN3HL_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HHC8005703.1"
                     /translation="MDNQRKPSLDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48723..49313
                     /locus_tag="ACN3HL_000807"
     CDS             48723..49313
                     /locus_tag="ACN3HL_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8005704.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49405..50910
                     /locus_tag="ACN3HL_000808"
     CDS             49405..50910
                     /locus_tag="ACN3HL_000808"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HHC8005705.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACN3HL_000809"
     CDS             complement(50994..52346)
                     /gene="celB"
                     /locus_tag="ACN3HL_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HHC8005706.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52346..52864)
                     /locus_tag="ACN3HL_000810"
     CDS             complement(52346..52864)
                     /locus_tag="ACN3HL_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005707.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(52880..53206)
                     /locus_tag="ACN3HL_000811"
     CDS             complement(52880..53206)
                     /locus_tag="ACN3HL_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HHC8005708.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53219..55198)
                     /locus_tag="ACN3HL_000812"
     CDS             complement(53219..55198)
                     /locus_tag="ACN3HL_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HHC8005709.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55219..55533)
                     /locus_tag="ACN3HL_000813"
     CDS             complement(55219..55533)
                     /locus_tag="ACN3HL_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HHC8005710.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55701..55994
                     /locus_tag="ACN3HL_000814"
     CDS             55701..55994
                     /locus_tag="ACN3HL_000814"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HHC8005711.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56072..57184)
                     /locus_tag="ACN3HL_000815"
     CDS             complement(56072..57184)
                     /locus_tag="ACN3HL_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HHC8005712.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57337..58185
                     /locus_tag="ACN3HL_000816"
                     /pseudo
     CDS             57337..58185
                     /locus_tag="ACN3HL_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58538..>59345)
                     /locus_tag="ACN3HL_000817"
     CDS             complement(58538..>59345)
                     /locus_tag="ACN3HL_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HHC8005713.1"
                     /translation="GYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSG
                     EVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPI
                     EFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLT
                     TGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVAD
                     SSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17755 a        12139 c        10381 g        19070 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatctgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ctattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcctcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct
    29461 ttttgtgtaa tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga
    29521 taatcccact ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt
    29581 ccatataacc acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct
    29641 gattcattac cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga
    29701 tcagtgcttg agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat
    29761 cttgcccttt gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac
    29821 aatctttatg ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa
    29881 tatgtcccat ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg
    29941 caccgattcc tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt
    30001 gcttcaattc cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt
    30061 agcgttcctt gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca
    30121 aaacgtatcc gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc
    30181 cgattccctt caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg
    30241 gtgttgtggt agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca
    30301 caaattttgt tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat
    30361 tgtccgaatc tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag
    30421 cagattcaat atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact
    30481 agacatattg aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt
    30541 aattgcaaac gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc
    30601 atgatgtttg atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt
    30661 agagaatttt tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag
    30721 acactgtgct tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag
    30781 tagcgtcact gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc
    30841 gactgttaca ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt
    30901 cgtggggttt tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact
    30961 atctgcttcg tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc
    31021 tttcatctga ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt
    31081 catgattgtt tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg
    31141 aaattccaca accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc
    31201 catttcctgt agaatactta tttttgctat ttccggtgta tctactaata cttttacttc
    31261 agagttttct ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata
    31321 ctcatttcct atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt
    31381 tttgcgatct tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt
    31441 ttcgatgatt cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc
    31501 ttctacaagc gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac
    31561 tttgatcatt cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa
    31621 ttggacagtt tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg
    31681 atacttacgt ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc
    31741 gaatcttttt ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc
    31801 agtatttaca atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc
    31861 ggtcagctgt tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa
    31921 acgaggtatc atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg
    31981 atgattttgc attaatgtct tccaagcata atctaattga tcatggggat agtttccact
    32041 aacttcataa gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt
    32101 ggtattccat tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc
    32161 atccgtttct tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt
    32221 ttgaactgct tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag
    32281 ttcatttgcg agatggattg cttttgatat atctttttgt accggttgat gatcaacacc
    32341 attcatcatc aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt
    32401 ccaaaaggca agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt
    32461 ggcaaatagc agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta
    32521 ttgggaagaa tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc
    32581 acggccaaac gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat
    32641 atttccaaat gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc
    32701 ttccatgcca atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg
    32761 caagatataa aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg
    32821 tcttttttct ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg
    32881 aaaactgttg aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat
    32941 cagtcgcatg tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga
    33001 aatgatatat actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa
    33061 gtaatccatg actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata
    33121 attttcagga ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc
    33181 tacaagtaaa ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat
    33241 agctaatgca atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc
    33301 gtactttcct tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag
    33361 ataatcttcc tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac
    33421 attactgtca tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt
    33481 ttgccctttt tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt
    33541 caatttctgt gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc
    33601 cacataacct aacacgacca ccgcaaacat attggatggt accagatatc cataacggca
    33661 agtatcatcg ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc
    33721 tcgcccgtca ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg
    33781 agagtgttca tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat
    33841 aaaagattga ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg
    33901 tattgggtag cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt
    33961 tgtatgatct gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg
    34021 atcgatattg atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc
    34081 ctcatcttct tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca
    34141 catcgctgga atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt
    34201 tgtcaacaga gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc
    34261 cccacatttt tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata
    34321 agccactaat aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc
    34381 caattatgtc tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat
    34441 tatttgaata tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa
    34501 tatttaatga tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac
    34561 caactgaaaa agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat
    34621 tgactgaatt agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta
    34681 aatccgcttc tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc
    34741 ttcttccata tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga
    34801 tgcaagataa acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag
    34861 caaaagagct aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac
    34921 atcttgactt actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa
    34981 aaatctatga gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg
    35041 ctgcctctta tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga
    35101 ctcatccaca atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg
    35161 gtttgacttt ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt
    35221 atatcactaa gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga
    35281 ccatgaatct cttgagacag catggttatc atatccctga agatttttca attatcggat
    35341 ttgatgatat ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt
    35401 ttgaacagtt aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc
    35461 gaccatccga tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat
    35521 aaaatgaata tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct
    35581 aatgggaact gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa
    35641 actacggatc aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac
    35701 cgtcttaccc atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg
    35761 atcaatggaa aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa
    35821 gaaagtatat tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct
    35881 acattgatac ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc
    35941 ggtttacttt tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg
    36001 gaaggaaaaa tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata
    36061 ttgagatttg aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac
    36121 tcgatcccgt tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt
    36181 atcagctcgg aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact
    36241 taccttgctc acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac
    36301 catgatcaac aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca
    36361 caaacatttt atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga
    36421 tctataaaac ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt
    36481 tatcctcttt attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg
    36541 aacagctata gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt
    36601 atgcctggga cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga
    36661 gacttgatgc ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat
    36721 ccaaattatg gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac
    36781 taccacgaat cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa
    36841 gttgccaagg tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac
    36901 tatcaaaata tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag
    36961 ttcagagaac cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg
    37021 caaagcagct ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt
    37081 gagagatata aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga
    37141 ggatatggtt ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta
    37201 gctatttcaa accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct
    37261 gaaatggcac agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg
    37321 ggttaccctg gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg
    37381 ggattttatc ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac
    37441 aaggctgttt tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg
    37501 ccgcagcaac aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat
    37561 tttacccatc aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct
    37621 caccctaaga aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa
    37681 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc
    37741 tcatattttt cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat
    37801 tgagaggttg tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt
    37861 tcctcatatt ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta
    37921 gtggagaggt cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg
    37981 gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt
    38041 ttatcgagag gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag
    38101 atttctagac aattttttat aagttatttc attacattgg ctttttcttt tatgattctc
    38161 cactgttttc tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga
    38221 aatacgtggt gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt
    38281 gcaaaagcag ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt
    38341 ttttcgtttc ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg
    38401 acacttcttt gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt
    38461 ccacattgtc actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct
    38521 gctgaagttc ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct
    38581 catcttccag atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc
    38641 gtatatcttc cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt
    38701 tttgagcgac ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg
    38761 tttgatcttt tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa
    38821 attgatgcaa ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag
    38881 aatctgtctc ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa
    38941 aacaacagaa gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc
    39001 cgtaatttcg ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag
    39061 tatcatgagt tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc
    39121 ctattatttc ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca
    39181 gttcttgata gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga
    39241 ttttcttgag gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg
    39301 cgcctaattg catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa
    39361 attcaaaatt atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg
    39421 gcattgtcac atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt
    39481 ctttggcatt ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct
    39541 tttttaaccc attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca
    39601 tccctccttg aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat
    39661 ataataactg ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga
    39721 accgtgaagt tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc
    39781 agtcatccct tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac
    39841 tttgacactt agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc
    39901 aactaatggc tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat
    39961 aaaatgatag gctactcgat taggataacg catttgatac aaatagacat atttttcgca
    40021 aaagtccagt tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa
    40081 agcggaaaac gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat
    40141 tcggatatat tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg
    40201 catatgtgcg tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat
    40261 gctatccaac atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt
    40321 tatgtcgatc cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat
    40381 agatacttgc tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc
    40441 taaaataatg ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact
    40501 ttttttatct agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa
    40561 attgtttttt tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat
    40621 gatcatttct tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag
    40681 tcgatttgtc gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc
    40741 taaaatcata tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc
    40801 tccttgtgtg ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt
    40861 tatttcccca cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac
    40921 gatatatatc gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa
    40981 agaaactaat tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat
    41041 gggttttgtt aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt
    41101 tttgatgatc ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc
    41161 atcacttgtc atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat
    41221 aacggtagca gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt
    41281 tagtaaggtt ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat
    41341 ctaattcttc acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga
    41401 caccaaacag gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa
    41461 taattatttt tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca
    41521 gattaggaac agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa
    41581 ataggcagag caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga
    41641 tttgaacaga taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa
    41701 atagcagatt gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga
    41761 tttctttata ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac
    41821 ctaatccaaa gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta
    41881 taatgaccca gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc
    41941 caaacattaa gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga
    42001 cctgattatt agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg
    42061 aataccgagg gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag
    42121 tttcgagtag taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc
    42181 ttaataccga gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt
    42241 cttttgtcac aacccctttg tctttattca ttattattct tgtcggaact catcatattg
    42301 tttttgcatt tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt
    42361 cggtaatgtt tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat
    42421 gacattagaa atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa
    42481 aatcggtgaa gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt
    42541 aatagactct tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt
    42601 atttggctga taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca
    42661 tgcttctccc tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag
    42721 ccctagaagt tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc
    42781 catttgtgct tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg
    42841 ttttgctgca tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg
    42901 cattagccaa gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg
    42961 aatgagtcct tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt
    43021 atcgtattgg ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt
    43081 attccctaaa ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc
    43141 tgccgtgttt ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga
    43201 ttggattcca tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac
    43261 ttgttgagca aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt
    43321 tcctttaata tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa
    43381 ttcagtcaaa tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc
    43441 gatatcataa ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca
    43501 gccaatgtaa ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac
    43561 ttccatcaat tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc
    43621 cgaattgcta gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc
    43681 caacaacaac gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc
    43741 tcctaatttt atgatttata tttttgtttc tttattcttt tactccgccg attgttagac
    43801 ctttgacaaa atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga
    43861 ctacgatcgc cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc
    43921 ttcctgctcc tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat
    43981 actgtagtgg aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc
    44041 agtaacccaa tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa
    44101 cgatctgaac aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg
    44161 aatcagagac cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag
    44221 ccattggcaa gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa
    44281 gataattggc caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa
    44341 aacgacggaa tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc
    44401 tattgatcag tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt
    44461 tatcctgcat ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa
    44521 aactgtaccc gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata
    44581 taaatggcaa aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag
    44641 ccgtcttatt gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc
    44701 tccttagaat aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa
    44761 caagacaaag ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc
    44821 tgtggatgtc aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc
    44881 accggaattc ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac
    44941 ggctaaaatc gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat
    45001 ctgctgccat ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc
    45061 cataacagat gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa
    45121 caccaagata aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg
    45181 tccagtgatc cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta
    45241 actgataatg acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac
    45301 gagtcgttta tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt
    45361 caaaaggata aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc
    45421 cgaagaaaat aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc
    45481 caagaaccca tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg
    45541 tatgtaaaag aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt
    45601 ataacgccat agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc
    45661 cctttcgatt cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa
    45721 gtatagggaa aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt
    45781 attagagaaa aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg
    45841 agggtcagct gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt
    45901 attagggaga tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta
    45961 acaaaagtct tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac
    46021 ggaaataagc cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt
    46081 tcagatggcg ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc
    46141 tcacttgttc tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag
    46201 gcagccaaaa ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt
    46261 tgaccattcg cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag
    46321 tttctgtctc ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc
    46381 catcaataat cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa
    46441 cctcagctag atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca
    46501 ccccgtcatt cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa
    46561 aaagatcttc ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat
    46621 cctgagtagc agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat
    46681 acgtaatgat ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat
    46741 cgcttttcac cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt
    46801 ctttgcggct gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc
    46861 atttcaaaag agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc
    46921 gtaaacgcgc tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat
    46981 aaccatacac taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt
    47041 tgctatcttc gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca
    47101 taatcaaggt aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc
    47161 gggctacttc atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg
    47221 tcgccaataa agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt
    47281 tcactagaaa cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca
    47341 gcatgttgga aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca
    47401 gtacattact tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta
    47461 acataacacc aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg
    47521 tcaattttgc cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc
    47581 cagtagacgc gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg
    47641 cactaaaaat cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca
    47701 tgatcttcat aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa
    47761 taataaacgg aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta
    47821 ttttgttttc gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat
    47881 acaaaaggac aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga
    47941 ccgccgtcac atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat
    48001 aaaaaatacg tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat
    48061 tgccttgcaa ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca
    48121 aagaacgcat cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag
    48181 aggcgatgta catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac
    48241 ggataaataa tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt
    48301 ttgcaatcgc agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt
    48361 atcccatatt gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg
    48421 gaatgatata gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag
    48481 agcctcgtgc cattttttct tgcggtgtta attgatctaa tgatggtttt ctttgattat
    48541 ccatcggtca gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga
    48601 aactggcaat cgattttata taacttttat aagaacaatt gtttttttga attcggtttc
    48661 gtttttttgg taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat
    48721 caatgacaca agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag
    48781 ttggattgaa ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg
    48841 gacatttagt tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc
    48901 ttatgatgct gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag
    48961 cgggaagtct gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct
    49021 cacatttctt ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt
    49081 acacagtcgg ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt
    49141 ttcggcttcc aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt
    49201 attatgtttt tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat
    49261 tgtttatgaa aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga
    49321 ttttgtcata gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa
    49381 ttgaataaag cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta
    49441 ttaaaagaaa atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca
    49501 gaaaaagctg aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg
    49561 tttttctgta aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt
    49621 attcaatatt atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg
    49681 gatatccgta aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa
    49741 ttgaaagtga tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa
    49801 gcaatcttgg atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg
    49861 ttagatggca aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat
    49921 cgtatgatgt cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca
    49981 caagcttaca aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat
    50041 atctcgcctg accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc
    50101 aagcgacaat tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt
    50161 gatttactta gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg
    50221 gaagaaagca attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct
    50281 tctcatgaag atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga
    50341 ttcaaccaag aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt
    50401 caagatgcac aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc
    50461 caatccaatg gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca
    50521 ttgctgaaat ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc
    50581 ccaggaaaca aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct
    50641 gacatcgcct ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa
    50701 gaaatcaatg aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct
    50761 gaagcgattc gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga
    50821 aaaggcgtgg atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat
    50881 gcaatcgtga agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt
    50941 ctaagaaaaa aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt
    51001 aacttttcac tagctaattc tgctgccttt tctctttctt catttaataa tttattatca
    51061 tagaatttga taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac
    51121 acagcagctt tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc
    51181 cacggcatct gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt
    51241 gtagcagaag ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt
    51301 ggcatcccga aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt
    51361 cctaacactt tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa
    51421 gtcgcacctg atccaccaac ggttacataa gaattgttga attctcctgc caacggataa
    51481 tttgcgcctt gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg
    51541 atgatattcg ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc
    51601 atgacaccaa gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt
    51661 ttgaagatat ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca
    51721 atgacaaatg ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct
    51781 ggcattttta tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc
    51841 gacataataa tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc
    51901 ctaataccat ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca
    51961 tcagtcatga tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc
    52021 gtgagcggat taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca
    52081 aacacaatgg caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac
    52141 aagtcactaa ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat
    52201 ggcaaaatat ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc
    52261 cccgctgcca tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc
    52321 aggtatttct gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt
    52381 catattgttt aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat
    52441 actgtataaa tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc
    52501 ctccattgtt atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg
    52561 gaatcactaa taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt
    52621 tcgtttggtg ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa
    52681 tcagaatcat cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt
    52741 gcatgttcat gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat
    52801 acatgttttt caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct
    52861 gcacaatgat ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa
    52921 cttccaataa tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca
    52981 tttctatttt tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat
    53041 gaagaatctc ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac
    53101 gcatcgagcg aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat
    53161 caaaagaagt cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt
    53221 attcgatcag tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt
    53281 cctgctgtac ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc
    53341 cttcattttc gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat
    53401 cccactgcat cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa
    53461 cagcgggatg tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt
    53521 gctggatctg ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt
    53581 gcagcaaatc atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt
    53641 tttcagacaa ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg
    53701 gtctatctga ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat
    53761 catcttcatt caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa
    53821 gatcaataga agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat
    53881 agccttttac acttaccact gtaatatttt taccgaattc actgactacg cgattcttta
    53941 atagttgggc actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag
    54001 ctctttcttt ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat
    54061 tgatggtata gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga
    54121 ctttgggatt ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc
    54181 tcaatcgaat catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct
    54241 ctactaatga aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg
    54301 atagttcctg atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca
    54361 aataagcaat ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga
    54421 tccgctgcgc cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct
    54481 tgatttcaaa cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct
    54541 gtatgataaa atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga
    54601 ctagctcttc aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg
    54661 aatttccata atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt
    54721 ccccttcgat ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca
    54781 atcgctcctt gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt
    54841 ctgccaaatc atccataaaa agaatggcat cttccaaaag caattggttc aatatatact
    54901 tttgtcgatc ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt
    54961 cttgccgact caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat
    55021 aacctggttt agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca
    55081 agtaattacg gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga
    55141 catactcctt cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta
    55201 tcatccactc ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc
    55261 tgtagggatt gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc
    55321 tcctaatttt ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc
    55381 aaaatcacta ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac
    55441 ctcttctctt ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat
    55501 tcctgccgca caaataatca atgctttttt cataaatcaa tcactccttt tatttttata
    55561 aaccaagcat atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga
    55621 aaaaatgtgt atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa
    55681 ttttttcagg aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg
    55741 gacaagccag aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg
    55801 cagaagaagg aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt
    55861 tactgatcga ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga
    55921 tggctcaaat aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca
    55981 ctgatttacc gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt
    56041 cactttttcc ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta
    56101 tttttcggat aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga
    56161 tattctcaaa aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg
    56221 ccaaagcacc aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag
    56281 ctagaccacc taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata
    56341 aaacacatcc aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg
    56401 acatcaatcc atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct
    56461 gaaaagggac atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca
    56521 tccaaatttt ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt
    56581 ctttgttctt ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa
    56641 ataataagct acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat
    56701 aaacaataaa gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag
    56761 cggttgccat taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc
    56821 atttgatcag ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta
    56881 tgatcgaatg ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga
    56941 ataaaaccac agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa
    57001 aacaaatggc aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc
    57061 acttttcttt tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt
    57121 gtagagactg ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag
    57181 tcatctatga caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca
    57241 actatttttc ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc
    57301 accacaaaat aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt
    57361 ctgagatcaa tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag
    57421 aaaaaaacat tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt
    57481 ggttctgctg tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa
    57541 accattgtcc actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag
    57601 cgctatacct gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca
    57661 aggcactcga tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg
    57721 tcgttatttt ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg
    57781 aaagagttga gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg
    57841 gttgtgaatt tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg
    57901 gcgagacaga aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa
    57961 ctatttcctt agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc
    58021 cacctacttt cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt
    58081 acttggtttt tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct
    58141 ttccgagaca aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag
    58201 agaaaaaatt acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat
    58261 aaacttgagt cattaggcaa aaaacactgc gaaactcaag aatgattttc gcagtgtttt
    58321 tgtatatttt ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc
    58381 acaaaattgt ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata
    58441 tttgtttgta taccccttct aaaatcggta gtttccattc aattgatggg tactagttga
    58501 ttttaaaaac tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa
    58561 attttatact gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga
    58621 tggtttctcc agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta
    58681 tatctgagct atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt
    58741 ctttttcgat cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag
    58801 tttctaccag ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc
    58861 ctgtggttag acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc
    58921 cttgcaggac ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa
    58981 gtcgattttc tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga
    59041 ttggtgtcgc atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc
    59101 ctggtgctaa gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca
    59161 gaacggttcc attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt
    59221 ggtcatcgat ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt
    59281 ctaccaccgc tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat
    59341 acccc
//
LOCUS       DBGZHO010000010        56383 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.010, whole genome shotgun sequence.
ACCESSION   DBGZHO010000010 DBGZHO010000000
VERSION     DBGZHO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.010"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            330..1175
                     /locus_tag="ACN3HL_000818"
     CDS             330..1175
                     /locus_tag="ACN3HL_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8005714.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACN3HL_000819"
     CDS             1456..2676
                     /locus_tag="ACN3HL_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HHC8005715.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACN3HL_000820"
     CDS             2673..5393
                     /locus_tag="ACN3HL_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8005716.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACN3HL_000821"
     CDS             5377..6321
                     /locus_tag="ACN3HL_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHC8005717.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="ACN3HL_000822"
     CDS             complement(6390..7400)
                     /locus_tag="ACN3HL_000822"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8005718.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="ACN3HL_000823"
     CDS             complement(7580..7924)
                     /locus_tag="ACN3HL_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HHC8005719.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="ACN3HL_000824"
     CDS             complement(7917..8351)
                     /locus_tag="ACN3HL_000824"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HHC8005720.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="ACN3HL_000825"
     CDS             8489..9226
                     /locus_tag="ACN3HL_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005721.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="ACN3HL_000826"
     CDS             9219..10430
                     /locus_tag="ACN3HL_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005722.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="ACN3HL_000827"
     CDS             10634..11416
                     /locus_tag="ACN3HL_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HHC8005723.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="ACN3HL_000828"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="ACN3HL_000828"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HHC8005724.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACN3HL_000829"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACN3HL_000829"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HHC8005725.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="comGA"
                     /locus_tag="ACN3HL_000830"
     CDS             14132..15061
                     /gene="comGA"
                     /locus_tag="ACN3HL_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HHC8005726.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /gene="comGB"
                     /locus_tag="ACN3HL_000831"
     CDS             15018..16067
                     /gene="comGB"
                     /locus_tag="ACN3HL_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HHC8005727.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /gene="comGC"
                     /locus_tag="ACN3HL_000832"
     CDS             16064..16342
                     /gene="comGC"
                     /locus_tag="ACN3HL_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HHC8005728.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /gene="comGD"
                     /locus_tag="ACN3HL_000833"
     CDS             16317..16787
                     /gene="comGD"
                     /locus_tag="ACN3HL_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HHC8005729.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16759..17106
                     /locus_tag="ACN3HL_000834"
     CDS             16759..17106
                     /locus_tag="ACN3HL_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005730.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17069..17494
                     /gene="comGF"
                     /locus_tag="ACN3HL_000835"
     CDS             17069..17494
                     /gene="comGF"
                     /locus_tag="ACN3HL_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HHC8005731.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /gene="comGG"
                     /locus_tag="ACN3HL_000836"
     CDS             17466..17825
                     /gene="comGG"
                     /locus_tag="ACN3HL_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HHC8005732.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="ACN3HL_000837"
     CDS             17997..19004
                     /locus_tag="ACN3HL_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8005733.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="ACN3HL_000838"
     CDS             19029..20213
                     /locus_tag="ACN3HL_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HHC8005734.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACN3HL_000839"
     CDS             complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACN3HL_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HHC8005735.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22338..22466)
                     /locus_tag="ACN3HL_000840"
     CDS             complement(22338..22466)
                     /locus_tag="ACN3HL_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005736.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22811..22954)
                     /locus_tag="ACN3HL_000841"
     CDS             complement(22811..22954)
                     /locus_tag="ACN3HL_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HHC8005737.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="ACN3HL_000842"
     CDS             complement(23177..23656)
                     /locus_tag="ACN3HL_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHC8005738.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="ACN3HL_000843"
     CDS             complement(23729..24013)
                     /locus_tag="ACN3HL_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005739.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="ACN3HL_000844"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACN3HL_000844"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="ACN3HL_000845"
     CDS             complement(24357..25643)
                     /locus_tag="ACN3HL_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HHC8005740.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="ACN3HL_000846"
     CDS             25781..26452
                     /locus_tag="ACN3HL_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HHC8005741.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="ACN3HL_000847"
     CDS             26418..26906
                     /locus_tag="ACN3HL_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HHC8005742.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="ACN3HL_000848"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="ACN3HL_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HHC8005743.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="ACN3HL_000849"
     CDS             27867..28631
                     /locus_tag="ACN3HL_000849"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HHC8005744.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="ACN3HL_000850"
     CDS             28864..31077
                     /locus_tag="ACN3HL_000850"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HHC8005745.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /gene="dtd"
                     /locus_tag="ACN3HL_000851"
     CDS             31088..31534
                     /gene="dtd"
                     /locus_tag="ACN3HL_000851"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HHC8005746.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="ACN3HL_000852"
     CDS             31705..32964
                     /locus_tag="ACN3HL_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HHC8005747.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="ACN3HL_000853"
     CDS             complement(33053..34000)
                     /locus_tag="ACN3HL_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHC8005748.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHIPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /gene="hisS"
                     /locus_tag="ACN3HL_000854"
     CDS             34394..35686
                     /gene="hisS"
                     /locus_tag="ACN3HL_000854"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HHC8005749.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="ACN3HL_000855"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="ACN3HL_000855"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HHC8005750.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="ACN3HL_000856"
     CDS             37579..38454
                     /locus_tag="ACN3HL_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8005751.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="ACN3HL_000857"
     CDS             38720..40603
                     /locus_tag="ACN3HL_000857"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HHC8005752.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="ACN3HL_000858"
     CDS             complement(40678..40962)
                     /locus_tag="ACN3HL_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HHC8005753.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="ACN3HL_000859"
     CDS             complement(40952..41686)
                     /locus_tag="ACN3HL_000859"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HHC8005754.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="ACN3HL_000860"
     CDS             41815..42438
                     /locus_tag="ACN3HL_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HHC8005755.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="ACN3HL_000861"
     CDS             42630..43751
                     /locus_tag="ACN3HL_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HHC8005756.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="ACN3HL_000862"
     CDS             43758..46886
                     /locus_tag="ACN3HL_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8005757.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="ACN3HL_000863"
     CDS             46905..50099
                     /locus_tag="ACN3HL_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HHC8005758.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="ACN3HL_000864"
     CDS             complement(50245..50952)
                     /locus_tag="ACN3HL_000864"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8005759.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="ACN3HL_000865"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="ACN3HL_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HHC8005760.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="ACN3HL_000866"
     CDS             52447..53100
                     /locus_tag="ACN3HL_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HHC8005761.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="ACN3HL_000867"
     CDS             53326..54324
                     /locus_tag="ACN3HL_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HHC8005762.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="ACN3HL_000868"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="ACN3HL_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HHC8005763.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18553 a         9727 c        11687 g        16416 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccgc cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tatatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt att
//
LOCUS       DBGZHO010000011        50350 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.011, whole genome shotgun sequence.
ACCESSION   DBGZHO010000011 DBGZHO010000000
VERSION     DBGZHO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.011"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(58..186)
                     /locus_tag="ACN3HL_000869"
     CDS             complement(58..186)
                     /locus_tag="ACN3HL_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HHC8005764.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(189..1562)
                     /gene="rlmD"
                     /locus_tag="ACN3HL_000870"
     CDS             complement(189..1562)
                     /gene="rlmD"
                     /locus_tag="ACN3HL_000870"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HHC8005765.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1673..2728)
                     /locus_tag="ACN3HL_000871"
     CDS             complement(1673..2728)
                     /locus_tag="ACN3HL_000871"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HHC8005766.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2738..4168)
                     /gene="gatB"
                     /locus_tag="ACN3HL_000872"
     CDS             complement(2738..4168)
                     /gene="gatB"
                     /locus_tag="ACN3HL_000872"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HHC8005767.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4165..5637)
                     /gene="gatA"
                     /locus_tag="ACN3HL_000873"
     CDS             complement(4165..5637)
                     /gene="gatA"
                     /locus_tag="ACN3HL_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HHC8005768.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5637..5942)
                     /gene="gatC"
                     /locus_tag="ACN3HL_000874"
     CDS             complement(5637..5942)
                     /gene="gatC"
                     /locus_tag="ACN3HL_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HHC8005769.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6048..8084)
                     /gene="ligA"
                     /locus_tag="ACN3HL_000875"
     CDS             complement(6048..8084)
                     /gene="ligA"
                     /locus_tag="ACN3HL_000875"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HHC8005770.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8101..10335)
                     /gene="pcrA"
                     /locus_tag="ACN3HL_000876"
     CDS             complement(8101..10335)
                     /gene="pcrA"
                     /locus_tag="ACN3HL_000876"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HHC8005771.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10490..12049
                     /locus_tag="ACN3HL_000877"
     CDS             10490..12049
                     /locus_tag="ACN3HL_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HHC8005772.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12160..14091)
                     /locus_tag="ACN3HL_000878"
     CDS             complement(12160..14091)
                     /locus_tag="ACN3HL_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HHC8005773.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14109..15023)
                     /gene="pfkB"
                     /locus_tag="ACN3HL_000879"
     CDS             complement(14109..15023)
                     /gene="pfkB"
                     /locus_tag="ACN3HL_000879"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HHC8005774.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15020..15772)
                     /locus_tag="ACN3HL_000880"
     CDS             complement(15020..15772)
                     /locus_tag="ACN3HL_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8005775.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15931..16140)
                     /locus_tag="ACN3HL_000881"
     CDS             complement(15931..16140)
                     /locus_tag="ACN3HL_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005776.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16151..17479)
                     /locus_tag="ACN3HL_000882"
     CDS             complement(16151..17479)
                     /locus_tag="ACN3HL_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005777.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17615..17770
                     /locus_tag="ACN3HL_000883"
     CDS             17615..17770
                     /locus_tag="ACN3HL_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HHC8005778.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17844..18431)
                     /gene="yihA"
                     /locus_tag="ACN3HL_000884"
     CDS             complement(17844..18431)
                     /gene="yihA"
                     /locus_tag="ACN3HL_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HHC8005779.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18514..19764)
                     /gene="clpX"
                     /locus_tag="ACN3HL_000885"
     CDS             complement(18514..19764)
                     /gene="clpX"
                     /locus_tag="ACN3HL_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HHC8005780.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20011..21300)
                     /gene="tig"
                     /locus_tag="ACN3HL_000886"
     CDS             complement(20011..21300)
                     /gene="tig"
                     /locus_tag="ACN3HL_000886"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HHC8005781.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21454..22386)
                     /locus_tag="ACN3HL_000887"
     CDS             complement(21454..22386)
                     /locus_tag="ACN3HL_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005782.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22543..23202)
                     /locus_tag="ACN3HL_000888"
     CDS             complement(22543..23202)
                     /locus_tag="ACN3HL_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HHC8005783.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23205..24230)
                     /gene="sppA"
                     /locus_tag="ACN3HL_000889"
     CDS             complement(23205..24230)
                     /gene="sppA"
                     /locus_tag="ACN3HL_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HHC8005784.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24243..24533)
                     /locus_tag="ACN3HL_000890"
     CDS             complement(24243..24533)
                     /locus_tag="ACN3HL_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005785.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24943..26748
                     /gene="glmS"
                     /locus_tag="ACN3HL_000891"
     CDS             24943..26748
                     /gene="glmS"
                     /locus_tag="ACN3HL_000891"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HHC8005786.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26820..28175)
                     /gene="glmM"
                     /locus_tag="ACN3HL_000892"
     CDS             complement(26820..28175)
                     /gene="glmM"
                     /locus_tag="ACN3HL_000892"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HHC8005787.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28199..29368)
                     /locus_tag="ACN3HL_000893"
     CDS             complement(28199..29368)
                     /locus_tag="ACN3HL_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HHC8005788.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29365..30252)
                     /gene="cdaA"
                     /locus_tag="ACN3HL_000894"
     CDS             complement(29365..30252)
                     /gene="cdaA"
                     /locus_tag="ACN3HL_000894"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HHC8005789.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30441..34121)
                     /gene="nifJ"
                     /locus_tag="ACN3HL_000895"
     CDS             complement(30441..34121)
                     /gene="nifJ"
                     /locus_tag="ACN3HL_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HHC8005790.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34319..34840
                     /locus_tag="ACN3HL_000896"
     CDS             34319..34840
                     /locus_tag="ACN3HL_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HHC8005791.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35539..36104)
                     /locus_tag="ACN3HL_000897"
                     /pseudo
     CDS             complement(35539..36104)
                     /locus_tag="ACN3HL_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36283..36939)
                     /locus_tag="ACN3HL_000898"
     CDS             complement(36283..36939)
                     /locus_tag="ACN3HL_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005792.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37507..38442)
                     /gene="whiA"
                     /locus_tag="ACN3HL_000899"
     CDS             complement(37507..38442)
                     /gene="whiA"
                     /locus_tag="ACN3HL_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HHC8005793.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38476..39474)
                     /gene="yvcK"
                     /locus_tag="ACN3HL_000900"
     CDS             complement(38476..39474)
                     /gene="yvcK"
                     /locus_tag="ACN3HL_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HHC8005794.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39471..40355)
                     /gene="rapZ"
                     /locus_tag="ACN3HL_000901"
     CDS             complement(39471..40355)
                     /gene="rapZ"
                     /locus_tag="ACN3HL_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HHC8005795.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40490..41221)
                     /locus_tag="ACN3HL_000902"
     CDS             complement(40490..41221)
                     /locus_tag="ACN3HL_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HHC8005796.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41225..42490)
                     /locus_tag="ACN3HL_000903"
     CDS             complement(41225..42490)
                     /locus_tag="ACN3HL_000903"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HHC8005797.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42753..45569)
                     /gene="uvrA"
                     /locus_tag="ACN3HL_000904"
     CDS             complement(42753..45569)
                     /gene="uvrA"
                     /locus_tag="ACN3HL_000904"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HHC8005798.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45579..47573)
                     /gene="uvrB"
                     /locus_tag="ACN3HL_000905"
     CDS             complement(45579..47573)
                     /gene="uvrB"
                     /locus_tag="ACN3HL_000905"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HHC8005799.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47832..49334
                     /locus_tag="ACN3HL_000906"
     CDS             47832..49334
                     /locus_tag="ACN3HL_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HHC8005800.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49336..50073
                     /locus_tag="ACN3HL_000907"
     CDS             49336..50073
                     /locus_tag="ACN3HL_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHC8005801.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
BASE COUNT        13904 a        10928 c         8861 g        16657 t
ORIGIN      
        1 aaaaagacta agaaacaata acaaaagtta acacttctta gtctttcttt agcacgtcta
       61 tttattaaag attttagggc cttttctcat gtttttacga tcattcttag gtgtttccat
      121 ttgtttggat cggcctccac cttgtttctt tttgatcaat tctttcattt tttctttttg
      181 gtccattttt attctccttt aacgaatgaa gcgactaatt cgatatgatg ggtttgcggg
      241 aaaagatcta caggctgaac tttcttcacg gcataacctg cttctgcaaa taacttagca
      301 tctcttgcaa aagttgccgg attacatgag atatagacga ttcgttctgg tgacatttcg
      361 attgctgatt caataaaatg atgatctaat ccttttcgtg gagggtcaac tacgatcaca
      421 gatggtttga tccctttttc ttgccatttt ttcataactt tttctgcttt tccgacttca
      481 taatgaacat tttcgatttt attatttaaa gcattgaact gtgcatcttc aattgcttct
      541 ggaataactt ccatcccata caccttatcc actctgtctg ctaaagacaa gccaatcgta
      601 cctattcctg aataagcgtc gatcacaatg tcttttttat ctaactcggc aaactcgatg
      661 gctgtttggt acagatactc tgcttgttga gtatttactt gataaaatga ctttgctgag
      721 attcgatagg tttttcctaa tagctgatct tcgatatagt ctctgccata taaaactttt
      781 tctttgtctc ctaaaatcac atttgttttt tcttcattga tattttggat gaccgaaacc
      841 acttctggca attcttcatg aatagcttca gcaatttcct tggatttaaa gaatttttct
      901 ttacgagtaa ctaaaacgac catcatttca tgggaataat gaccacgacg gataatgatg
      961 tgacgaagct gtccttcatt tttttcttca ttatatcctc gtacttggaa ccgttgcaag
     1021 atatctctga ctactttgat tgcttgatcg atgacaggat cttggatata aaaatcttcg
     1081 atagggacta gatcatggct attctttttg taaaaaccgg tggctaactg tccatcgata
     1141 cggcgaacag ggatctgtgc tttattacgg tagccgaatg gttctgccat tccgaccgtt
     1201 ggaagtacag gaacttctgg catcttagca atcttcgcca ttacatgctc tacttgtttt
     1261 tgtttgaaga caagctgttg ttcatacttc aaatgggcta aaggtgcgat acctatgcga
     1321 agtaatgcat tgttttctac aggctgacga tcaggtgatt gtgtaataaa tgtttcgact
     1381 tttccatatc caaacttatt gcctgctttt actactagta tttctacttc ttctccaggg
     1441 agtgcatttt cgataaataa tggataacca tcgatttttg ctacccccat tccttcataa
     1501 ctcaagtcga cgatttcgac tgtatatcgt tcgtttttct ttactatttg ctgttctgtc
     1561 atattttgct cctttaagcc tatttttcaa tcctactgaa ctctactata aatcagctaa
     1621 ttacacaact aaaaccggca ctgaccttac tacgttcagc accggctttt gattaattct
     1681 tttgattagg tgtttcgtct gctatttttc cgtcaccgtc gatatcttca tccgttaaac
     1741 gttcgacttc ttttacgaat tctttgctga caacctctaa ttcttcttca tctgtacctg
     1801 tgattgcttc atcaggaatc tgatcggtat tggcaaagaa ctcaatgtgt tgatgaagat
     1861 tttggaaatg catcggtgct tccccgccgt attcaccatc taagttgatc attactggtc
     1921 gattgatatc atcttctgtt tcaacgaaca aactgcttgt tttggtatag attattcttg
     1981 gatcatcgac atgtcgaccg ccattcagca tgagtgctgc aatatgcaag atctcaaaga
     2041 tatttgctgt cttcacaatg attaaagaaa acttcccatc atccaatttg gcatctggcg
     2101 cgatctgttc gaatcctcca acagagttcg tcagccctag gaaaaacatc gaagcatttc
     2161 cgatatattc cccttcatca tacttcaagc gcattttgat tggctttact cgagggagca
     2221 tctctgctcc tttcgcaaga taagcaagat aaccaaaaat actctttagt tctgatggaa
     2281 cttcataagt caattctgtc aaatagccac ctgcagcgat attgatgaag taactgttat
     2341 cagaaaggcc gatgtccatt tttacggttt ggtgtttttt tatcacttct gctgctgctt
     2401 taatattatc tctaggaatt tttaatgctc gagcatagtc gttcgttgta ccagctggga
     2461 tgatggccat tttaggacgg tgttcaagcg gagcgattcc attaaccact tcgttgattg
     2521 tgccatcgcc accagctgcc actactagat caaaacctag ttctgcgact ctacatgctt
     2581 cattcttggc tgaatctggt tctggtgtag ttgcataggc gctggcttca aatcctgctt
     2641 cttctaatgc ctgtaggata tccgccaaat tttttttcaa taattctttt cccgaggtgg
     2701 ggttataaat tacgcgtgct tttttcattt tcagcctcta tcgtttcgct aattcatctt
     2761 taagtagctt attcacgaca ccaggatttg cttgtccttt agttgctttc atgatttgac
     2821 cgactaggaa gccaaccgca cgatcttttc catttttgaa atcatcgaca gattgttggt
     2881 tgttatccaa aatttcatta atgattggca gtagtttgtt cggatcagat aattgcaccc
     2941 aaccattttt ttcaactact tcttgggctt ctccgccatt tgtgatcaat tcacggaaga
     3001 cttttttggc gatttttgag ctgatcgttc catcggcgat caaacgaatc attcctgcta
     3061 agttctcagg tgtcaatttt gtctcagcta attccagttt ctcactgttc aagtaagcag
     3121 aaacttcacc catcaaccag ttagatgctt gcttggcatc tgcaccattt tccaaaacag
     3181 cttcaaaaaa atcagacatt tcttttgtaa gtgtcaatac cattgcgtca tactctggaa
     3241 gtccaaactc acggatatag cgttcgcgac gagaagctgg catctcaggc aaactagctt
     3301 ttactttttg aatccattcg tcatcgatca cgaatttcgg gatatcaggc tctgggaagt
     3361 aacgataatc actagaccct tctttgacac gcatcaaaac tgttttattc gttgtttcgt
     3421 caaaacggcg tgtttcttgt tggatttctc ctcctgaaag aagaactttt gcttgacgtt
     3481 tttcttcaaa agctaaacct tttttcacga aagataaaga gttcaagttt ttcaattctg
     3541 ctttcgtacc gaactcttct tgtccataag ggcgaagaga aatattggca tcacagcgca
     3601 tagagccttc ttccattttc acatcgctga cttctgtaaa ttggataatt gatcgcaatg
     3661 cttctagata agcgtatgct tcttctggtg aacgcatatc agcttcagaa acgatttcga
     3721 tcaaaggcgt gccttgtcgg ttcaaatcaa cgtaagaata accgccaata ccatgcatgt
     3781 tttttccagc atcttcttct aaatggacac gttcgatccg gatttttttc tttttacctt
     3841 ctacttcgat ttcgatccat ccgtcatgac cgattggttg atcaaattgg gaaatttgat
     3901 atgcttttgg attatctggg taaaagtaat ttttccggtc aaaatgagta tctttagaga
     3961 tttcacagtt taatgccaaa gctgctttca tcccgaattc cagcgcagct ttattcatta
     4021 ctggcagcac gcctggataa ccccagtcga tcacgtttgt attgctgttt ggttctgcac
     4081 caaaatgagc tggcgctgga gagaaaattt ttgagttggt ttttaactcg acgtggactt
     4141 ctagtccaat gactgtttca aaattcattc gtctttccct cctaaaatag ctggttgttg
     4201 tttatggaat tctgttgctt gttcaaacgc atatgccgct tgatacatcg ttttttcatc
     4261 aaaataatta ccgatgatct gcaatccaac tggtaatcct tctgataaac ctgccggtac
     4321 agacatacct ggaagtccag ccaagttgac agggatcgtt aagatgtcac tcatgtacat
     4381 tgtgattgga tcgttaatgt tctcaccgat tccgaatgca actgttggtg aagatggccc
     4441 gatgatcaag tcataatctg caaagacttt ttcaaaatct cgtttgatca atgtacggac
     4501 ttgtcccgct tttttgaagt aagcgtcata ataaccagca cttaaggaga atgtacctaa
     4561 catgatacgg cgttttactt cttcaccgaa tccttctgaa cgtgagttga catatacatc
     4621 atctaatgat ttcacatttt ctgagcgata accgtagcgg ataccatcga atcgttgcaa
     4681 gttggaactt gcttctgatg aggcaatgat ataataaaca gccacaccgt attttgaatg
     4741 aggcaagctg acttcttcca caacagcacc taatgaacgg aatgtttctg ctgctttcaa
     4801 tacagcttct tttacgccag gggccacacc ttcgcctaag tattctttag gtaaagcaat
     4861 cttcattcct ttgatgtcgc ctgtcagtcc ctctgcaaaa tcaggaactg aaacgcctga
     4921 agaagtaccg tctttttcgt cataaccgct gatagctgtc aatgctaatg cattatcttt
     4981 caccgtacgg gtcattggtc cgatttggtc aagagatgaa gcaaaggcaa tcaaaccaaa
     5041 acgtgagaca cggccataag taggtttcat ccctacgatg ccgttaaaag ctgctggttg
     5101 gcggatactt cccccagtat cactacctaa agaaactgga atttgtccag ctgcaactgc
     5161 tgctgcagaa ccaccagaag agccaccagg tacttttgtt gggtcccaag cattttttgt
     5221 tttcttgaaa taagaagttt ctgtacttcc acccatagca aattcatcca tgtttagctt
     5281 accaacaggg atcatatctg cttgatagat tttatccatg accgttgcat cataaattgg
     5341 ttcaaaattg taaaggatct tagatgcagc ggttgtcaag atatcttttg ttacgatatt
     5401 atccttgata ccaattggaa taccagcaag gacgttgctt tcatcaatcc ctttttcatc
     5461 taaagctttt gcctgttcca atgctttttc ttcgttcaat gtaatgaatg cttcgacctc
     5521 aggctctgtt tctttgattc gttcaaatgt tgcttttgtc aaatcttgta cagtgatttc
     5581 tttcgataca agcatatgat gcagttcttc tagagaacga ttgtgtaatt ctgtcattat
     5641 gcgccagcct ccccattatc gatgattgcg ggtactttga taaagccgtc ttctgtttcc
     5701 ggcacatttt tcaataattc atcgcggttc catccagctt gcgcccgatc ttgtcgcatc
     5761 acgtttactg tttcaaccac attcgacgta aatggaacac cttctgtatc tacttcttcc
     5821 agcatttcaa ccatatcgat gattttacct aattggtcgg taaaacttgc aagttcttca
     5881 tctgcgaacg caagttttgc taatttggca acgtgtttca cttgttcttc actaatcgcc
     5941 atactacccc ttctttctaa acgagttaaa aactttgctc tctattttaa cacaagagtg
     6001 ccgtgtctga aattgtttat tgaaatttgt ctgaaaaaac tcatttttca ttcttctact
     6061 gagcgacttt tagccaatgc atctgccatt tgatcttctg tccaaacttc gattcctaat
     6121 tcttgtgctt tggtcagctt gctgccagca tcttctcctg ctaccacgat atccgttttt
     6181 ttcgatacgc taccagtcac tttcccgcca agattttcga tcgtctcttt tgcttcttca
     6241 cgagtaaatc gtgttagttt accagtaagg actactgttt tttctttaaa aggagactcg
     6301 acttcttgca attgggcatt tcgaagccct ttgtattcga aattgacgcc tgcttgtttt
     6361 aattcattca tcaattcatg gacttcttcg ttactgaaat aagtgactac actgtcggca
     6421 atgatatcac cgatcgtatc aagcgcaata atcgactcat agtcactttt actcaatgtt
     6481 tctagatcac cgaaatgttc tgctaaaatt tttgctgctt tcgctccgac atgtcggatt
     6541 cctaacccga aaatcaaccg ctcgaccgaa ttatctttgc tgttgtcgat tgctgtcaaa
     6601 atattatttg ctgatttttc ttttattttg tccaacgtca ataactcttc ttctgtcaat
     6661 ttgtaaagat cagcaacatc tgctactagt tttttatcat acatctgttc tagtacgcgc
     6721 ggccccaacc catcgatatt catcgcattt cttgaaacaa agtggttcaa accttctttc
     6781 atttgagcag ggcatttagg attgatgcac cgtaaggcta cttcttcatc caaatggaca
     6841 agttcacttc cacaaactgg acaatgtgta ggcaattggt attcttcgct gtctttaggt
     6901 cgtttatcta acacgacttg cgaaacttct gggatgatgt ctcccgcttt ataaatcaga
     6961 actgtatctt tcaagcggat atccttcaac ttaatataat caccgttatg caggctggca
     7021 cggcttactg tcgttcctgc tactcggact ggtgtcatga tagctgttgg cgttactacc
     7081 cctgttcgac cgactgtcca ttcgatgttt tcgattagcg tttcaacttc ttctggcgga
     7141 aacttgtaag ctgctgccca tctcggtgct ttgacagtaa aaccaagttg atcttgtagc
     7201 gagaattcat tcactttgat gacgattcca tcgatttcat agggcaaatc cacacgtttg
     7261 tcatgatatt cttcaatgta tgaccacact tcatcaatcg aatgacatag acgtttttcc
     7321 cgattcgtgt ggaatccaat tttttctagc tcttctagcg catcatactg ggtttttgct
     7381 tgcataggac cgaaatcagc tactgtgtat aaaaaagtgt ccagatttct tttcgctgtg
     7441 attttagaat ctaactgacg caaagaacca gctgcggcgt tccgaggatt cgcaaagata
     7501 tcttttccct ctgcttctct gtcttggttc aattggacaa atgaccgttt tggcatgaaa
     7561 cattcgcctc ttacttcgat gttcattggt tcttttaatt tgattgggac cgaccggaca
     7621 gtttttaggt tttcagtgat gttttctcct acagttccat ccccgcgagt cgcacctctc
     7681 acgaaatttc catcttcata acgcaaagaa acggaaagtc catctatttt tagttcacag
     7741 caatagtcaa ctacacgtcc cactgctttt tgtacacgtt gatcaaaagc tatcagctct
     7801 tctttgctga aaacgtcgtt caaactgtaa agcggaatat catgagtgac tttttcaaaa
     7861 ccttctaata cttttccgcc tactcgttga gtgggagaat cagacgtgat caaatcagga
     7921 tattgttcct caattgctac taattctgcg tattctttat cataaacata gtcttccact
     7981 gttggtttat cttctacgta gtattcgcga gaccattggt tcagtcttgt acgaagttct
     8041 tctgctcgtt tagcagcttc gtcaatcgtc atttcatgtt ccatcattta ccctccacta
     8101 ctaagctttt tcaattggcg caaaggcagc caaaagacgt tttactcctt gacttgggaa
     8161 agccacatct agttctagat ccttcgacgt cccgcttact cggacgactg ttcctagacc
     8221 ccattttttg tgtttgactt tatctccagg tttccagctg ttattttccc ctccagtagc
     8281 acttttagag ggaacaaccg ctgtctctgg ctgtttatag ctatatgctg tttttttagc
     8341 gaatacaggt gtttttttag gcgtaggacg catgccttcg atttccagta actcctgatc
     8401 gatttcttct acaaaacgag aaggtcggtt atattgcgtc cgtccatata atgttctgga
     8461 gaaagcattt gttaaataca acgcttcttc tgctcgcgtg atccccacat atgcgagacg
     8521 gcgttcttct tccagttcgc tttcttccat caatgctcga gataaaggaa aaaccccctc
     8581 ttctagacca atcaggaata caactgggaa ttctaatcct ttggctgcat gcaaagtcat
     8641 caatgtcact tgggaagcat cttcttctaa attgtcaata tcggaaacaa gtgccagatc
     8701 atttaagaag accgttagtt tttcttctgg tgcatcagcg tcttcttcat tttgctgttc
     8761 gaattgtttg tcgaattctt gtgtgaccgt taaaaattcc tccaagtttt cgatgcgtgc
     8821 ttgtgcttct aatgtatttt ggatttttaa gtcttctaga tatccgctac gatccaaaac
     8881 ctctttcgtc aattctgtca ctgtcaagta tgggatcatc tgagtgactt cttggatcat
     8941 ctctccaaat gcacctaatt gctgtcctgc ttttccaccg atatttgcca gatccacatt
     9001 ttgcgctgct tcaagcagtg gccattcatg aagagaagca aaactgcgta gtttttcgat
     9061 agatcctggt ccgatgcctc gtttgggcga attaacgata cgctcaaaac tgattgaatc
     9121 ttgaggattt gccagcacat tcaaatacgc taaaatatct ttgatttctt tacgatcgta
     9181 gaacttgtgc cctccaacca ttttataagg aatatttgct ttcaacagag tttcttccat
     9241 tacacgagat tgtgcgttcg tccggtacaa gatggcaaag tcgccgtaat tccgatgatt
     9301 gcttcgaatc tcttcttgca tccgatctac gataaaacgg gtttcgtctc gttcattatc
     9361 tgcacggtag taagtgatct tgtttccttc tttgttttct gtccacaagt tttttggttt
     9421 tcgattgcta ttgttttcaa tgacttggtt tgctgcgcta aggatgtttt tcgtggagcg
     9481 atagttttgt tctagcaaaa ttactgcagc atctggataa tctttttcaa aatccaagat
     9541 gttctgcata tctgcaccgc gccagccgta aatactttga tctgcatctc ccacgacgca
     9601 caggttccta aatctacctg ccaataaatt gactagcgta tactgtgcgt gatttgtatc
     9661 ttggtactca tctacatgaa tataatggaa tttgttttga taatatgtga gtgaatcagg
     9721 atgttcttca aataatcgaa tcgtattcat gatcaggtcg tcaaagtcca tacattgatt
     9781 atattgaagc tctttttggt aagcagcata acattttgcc gcaatctctt cgtaataact
     9841 gccttgcatt tttgcaaaat cctgaggggt ctgcaggctg ttttttgctt gagagattgt
     9901 tcctaatata cttcgaggat catatttttt cggatcaatg ttcagttctt ttagtatccg
     9961 tttcatcaag gtcagctgtt cagaagaatc gatgattgta aagttccggt tatacccgat
    10021 aaaatcaaca tctcttctta aaatacgcac acacatcgag tgaaaagtcg atacccagac
    10081 atcttcgcct ccagatgcga gaatcgcatt gacacgttct ttcatttctt ttgcagcctt
    10141 attggtaaaa gtaatcgcta ggatgttcca aggattgact tctttttcct caatcaaata
    10201 ggcaatgcgg tgtgtcagca ctctcgtctt tccacttcct gcacctgcca ttagcagtaa
    10261 tggtccgtca gtgtgaagaa cagcttcttt ctgacggggg ttcatcccgt ttaataattc
    10321 agctttggat gacattaaca acatcctttc ttttatcaat cttgttaatt atagcatttt
    10381 cttggctttc attaaactag ctagttcaaa atcatttgtt tctttttatg gatttttcct
    10441 tgtcaattcg ttgatttcgc gctaaattaa aagaaagcga ggcgtttgaa tggaaaaaaa
    10501 aggaaaaatc aagaaattag ataagactca gatatatttt attctaaaag gaatatttgt
    10561 tggactgctg acaggaatcg tcgttagcct gtttcgatta tctatcgaaa agctaagcga
    10621 tttagttcga agtatctatg aaatgagtcg ggaacagccg atttacttaa ttggcctagc
    10681 tatttgctgc atccttgcag catttttcgt gggttatctg gtcaaaaatg aaccggatat
    10741 caagggaagc gggattccac aagtagaggg acagcttcgc ggggaattat caatgaactg
    10801 gttctctgtt ttatggaaaa agttcattgg cggtgtactt tcagttggtg cgggcctttt
    10861 tctaggtaga gaaggacctt ctatacagct tggcgcatcc attggacaag gagctggaca
    10921 attgtttcgg agtccatctt cagaagaaaa gattttaatt tctagcggtg caagtagcgg
    10981 acttgcagca gcattcaatg ctcctatcgc aggattactc tttgttttag aagaaatcca
    11041 tcactccttt tctccacttg tttggctgac atcatttgct tcagcaatca ctgctaactt
    11101 cgtctctctt tactttttcg gcttgagacc tgttttatat ctaggtgacc ttccttcttt
    11161 gccgttgaaa tattatggtt ccttagtgat cttaggagta cttctaggca tcttaggttt
    11221 tatttatcag aaggtcttgc tggctttgcc aaaattttac aaccgattgc ctttaccagc
    11281 ttattttcac gggttcgttc ctttcttgct gattttgcca attggttatt tatggcctag
    11341 tactctaggc ggaggcaatc aaatcgtttt agcttttgga catgcttcct tgccaatcat
    11401 tatgattatc ggtttgtttg ttcttcgatt cgttttttcc atgatttctt acggtggtgg
    11461 tcttccaggg gggattttcc ttccgatatt gacattgggg gctttaatcg gtagctttta
    11521 tggaaacatt atggttgatt tcgggatgga tccaatctac atcaaggatt ttgtcgttat
    11581 tgccatggct ggttatttca cagcgattgg aaaagcaccg ctgacagcaa ttattttagt
    11641 gacagaaatg gttggctctc ttaatcatct gatgccttta ggattggctg ctcttgttgc
    11701 ttatatcgtc aatgaccttc tcggcggtaa tccaatttac gaatcattat tggaacgtct
    11761 acttggaaat actcagaccg cctcactaaa aggtgcaagg acaacttttg attttccagt
    11821 aacggcagag agttctttag acggattaat ggtacgagac ttcaattggc ctaaaaatat
    11881 gctgctaatc tctatacgca gaggaaatca ggaaatcttg actcacggtg atacgatcat
    11941 gaatgtagga gatattttgg ttatcttgac tgatgaagca aacttgccaa gaatcaagca
    12001 ggaaatcgag gctaaatctt ctatcacaaa tttgaagcaa tcattttaac gaacatggaa
    12061 aaactatttt acaacaacta ttcatctaca ctacttgatt ctatatgatt ctataaaaaa
    12121 agaagagact gggaaaaacc agcctcttct tttttatttc tatgcttctg ctgctgcagg
    12181 agcttttctc aataaaccat aaatcacacc agatacgact gctccgatag caataaacac
    12241 caaatacatg accgggtgac tcagtaagaa tacaacgaaa atcccgccat gaggagccag
    12301 taatttgatc ccgaaagctc cgactaatcc gccagttaaa gcagaaccaa taataaaact
    12361 tggaatggca cgaatcgggt cagctgctgc aaatggaatc gatccttccg tgacaaacga
    12421 tagtcccatc acgatgttcg tcaaaccagc atcttgatct gttttgctga atttattctt
    12481 aaacaaacgt gtagcaacga aaattgccaa tggaggtacc attcctccag ccataacaga
    12541 agccatcacg acacttccgc cagttgcaac agtcgtagct aaagttgctg taccaaacac
    12601 ataagcggct ttgttgattg gaccgcctaa atctgccgcc atcattccag ctaataatgc
    12661 accaagtaaa gcagcattcg aaccactcat acttgtcaag aaaccgttca atgcatcatt
    12721 gattgctttc atagggacat tgaccagcaa catcaagaaa ccagtaatca gtaagccaaa
    12781 cactggataa aagaggatcg ttttaattcc atccaatgat tttggtaagt tcttgaataa
    12841 tttacgtaaa aatacgatga cataaccagc taagaatcca ccaatcagtg cacctaagaa
    12901 tcctgcaccg cctgtattag ctaatgcacc agcagcaaat ccaacgatca aaccagggcg
    12961 gtcaccgata cttgaagcaa taaatcctgc taataccggc agcatgaaac caaatgcagc
    13021 ttgtccgatt tggttgaacc agctagcagc ttgattgtaa ttccctagat ttgataattg
    13081 atcatgtggc acgccaataa attggtcgat catgaaagaa agcgcaatag cgattcctcc
    13141 accaataacg aaaggtaaca tgtgtgatac gccgttcatc aaatctttgt aaattctttg
    13201 tccgatagta ccatccgcat ttccttcttc tgaactgctt tcttttccat caccatggaa
    13261 tactggtgca gtaccactaa gggctagatt gatcagctct tctggtttac ggataccatc
    13321 actgacagga cgattgatca gttcttttcc gtcaaagcga ttcatctcta cttttttgtc
    13381 tgctgcaacg attacacctt ctgcacgggc gatgtcttca gcagtcaatc ggtttttgat
    13441 tccttctgaa ccgttcgttt cgactttgat ctccacaccc atttctttcg cttttttctt
    13501 cagagcatct tctgccatgt aagtgtgagc gatccctgtt ggacaagctg taacggcaac
    13561 aacgaatttt ctttctggat gagcagaagc ttctgcagct tgtgtttctt gttctgcttt
    13621 ttcttctgct tctttttgct cttcagctgt ttggaacaag tcttggactt cttctggtgt
    13681 atttgcttct tttaattttc ctacgaaatc tgcatcaatc agcaatcgag atagtgctgc
    13741 taatgcttgc aaatgtgtgt cgtttgcgcc ttctggagct gcgatcatga aaaacagata
    13801 agttggctgt ccgtctaagg cttcataatc tactcctttt tggctttttg cgaataaaac
    13861 tgttgcttct ttaactgcac tgtttttcgc gtgaggcatg gcgattccat caccaagacc
    13921 tgtagaagtt tgtgcttcgc gggctagaat tccttcttta tatgtttcga tatcggaaat
    13981 ccggccggca tcaaacattt tttggaccat ttcatcgatt gcgccttttt tatcagtcgc
    14041 ttgcaaatcc atgatcatcg cttctttgac cattaaatcc ttgatattca tgattatcct
    14101 ccttgaaact aatcaatttt tgtgatttca acttctggca gcaactcatc aatcaattcg
    14161 cgagctgcca agtcatcaga aaaagctgtt gcgcttccgc aagcaactcc ccatttaaag
    14221 gcttcgattg gatctttcgt acggctgtaa gccccaataa agccggcaat cattgaatcc
    14281 cctgcaccta ctgaattttt caatgggcga actaatacat tcgttttata agttccttgt
    14341 tccgtgaaga gcaaagcacc gtctccagcc attgagatca gcacattctg tgccccttca
    14401 gctagcaatt ttttaccata cggaatgatt tcttctacag attggaaggt tgtattgtaa
    14461 agctcagcta attcgtgatt gtttggtttg atcaacaatg gtttcttaac aagtgcattt
    14521 tttaggtcat cacctgttgt atcaatcacg aaatctgcac ctttttctcg aatgatatca
    14581 atcagttctt gataaaatcc ttttcgcagg ctagccggcg cgcttcctga caatacgacg
    14641 atatctcctt gtcctactgt tcctaatgct tgcttcaact catcgatttc ttcatctgaa
    14701 atagatgggc ccaaaccgtt aatttcagtt tcagtatctg attttagttt gatattgatt
    14761 cttgtatctt cttttacggt tgtgaacaaa gactggattt gttctttttc aagccacttc
    14821 gaaataaatt cgccagtgaa ccctcctaaa aaccctagtg ctgtagattg agaatcgatc
    14881 cgtttcaaaa tacgggaaac attgatccct tttcctccag gtaacttgaa gtcttccttc
    14941 attcggttca aatcgcctag ttttaaccca tctacgcgta cgatataatc aattgatgga
    15001 ttaagtgtta ctgtgtaaat cattgtattg cctccttaat tgttgtcttt tcacggaatt
    15061 cattaacgaa ttctaatgga caacgctcgg ttatgatcgt ggctgcttcc aaaggtgcaa
    15121 cagaggtgaa ggacaactgg ttgaatttgg tatgatcaat caatacaaat gtctcttcgg
    15181 aatttttcat ggctaaacgt ttaacagctg cctcttctgg gtccggagtc gtgaatcctt
    15241 gttcaagatg ggcaccgttc attcccataa atgctttatt aaaatgaaaa ttttttagtt
    15301 gttctatcgc attagatcct aaaacagcat tagttgccag ctttatcgtt ccacctaaaa
    15361 taatggtagc aagctccaaa tcaactaaat ttgccgcatg ttgaacggaa tttgtcacta
    15421 ctgtgatctg ttttccttgc agaaaaggaa tcatttctaa cgtagtagag ccagcgtcta
    15481 aataaatgac atcttcgtca ttaatggttt cagctgccga tttggcgatt tgctgttttt
    15541 cgtgaacgtt tttgagtgat ttttcactca tattctgctc aaaattcaat aattgctctt
    15601 tcttagctcc gccatgaact ctttctagaa acccactatt ctccagctct tgtaaatcac
    15661 gtcttatcgt tgattcagaa gcattaaaaa ggtttacaag atcttgtgat ttcacgattt
    15721 tctgctgttc aagcaagtct aggatttttt gtctacgttc ctctgtaagc attttcacga
    15781 tcacctcaat acaaataata gcatattttt tttctactcg caatataaat cagtcaaaaa
    15841 cgttcataaa aattataaat cagtcaaaaa aaaataaaaa accagtcaaa aagactggtt
    15901 ttttattttt ttgtctatca tcaagccgtt ttatcgtttt ttattttcgc ttcttgtttt
    15961 tttcatataa acagaagcag gttttctttc cttatgaaga agataataat aaagtcccat
    16021 cccgccaaac atgaccaaaa aaccgatgac tgatcgaata ggaaaattag gaacaaaaaa
    16081 gagacagacg gataataatg atgccggaac cattattcga taatagagtt gtttatccat
    16141 tttcttcacc tcatattttt tgtaaagtaa tcaattgttc taattctcgg taatctaaaa
    16201 attgcacacg cagatgctgc tcacctttct tgacatcgaa ttggatactt cgccgctttt
    16261 tctttattcg tttgaaggta acatcagaga gtctatgttt gatttccttt aacggtaatt
    16321 ctgacaggga ttctgaagga acatagattc ttaaggataa aagatactct tgatattttt
    16381 catctgttac ctctacttct agatattccc taatataata acaataagct tcgattccat
    16441 tatccaaagc aacagtcgga tcgataactt tatagcacat catgcgcgag cgattctcgt
    16501 caacccaagg aaaatacgcc tgagcattta gtgttccgcg aacacgcctt tctttataat
    16561 ctccttgttg aatatcataa ctttttgtta caaaaaatga agcattcttt ttaggaacag
    16621 gttgcatttg tgcattctga tactggacag attggatcgt atggtcagtg taaatgtatt
    16681 caacgaatgg cggtttcaat aaaccgacac cattgtccca agcaagatga tcaaacccaa
    16741 gctggtccct aaaataggat tgaaacattt gattgtttgg cttttgccag ttaaaggggt
    16801 ctcgataaag ctggatacat atgacttcgt tttctaattc cttcactttt tctacttgtt
    16861 ggatgtcgag aaaaatcggt ttagggatga tttgatgata atagcgacta taatacattt
    16921 cccaacacga agtgaaacat aaaccttggt aaaaaagatc gtatcctgga aattggttgc
    16981 aatcgactac tacttccccg ttttgttgtt tcattttagg taaatgttcg atttcatcct
    17041 ttttctcaaa caatagccgt tgagagatct gttttgtatt gtgatagata aactcgctat
    17101 aagctcgcat ataggcgaac accccatgag caatcatttt tttctgaatg aagtctcgaa
    17161 tcaaaaattg cttttctttg aaaacagaga tagacaatac attttttatc aataattgat
    17221 tatcttccaa gcgaaaacta cattcgttct cgtcatttcc tacaactaac caactttcgt
    17281 ctcttaccga tgctagcatt attttttctt gaagctttcg aagatcatac ggatccgctt
    17341 gttgtgtgaa agagcggata aatgttggct ggatcaacag acgtgtcaaa atagcccaat
    17401 cgcttatttc ctgttttttt tcttcttcat ttaagtctgt gagctggata gtcatcaata
    17461 atttatcttc gccaatcatt ttctcacctc tttaaaatct ttttataatt taattataac
    17521 caacgataaa gaaaaactaa aactttatgt cttagaaacc aatttggacg attacatgat
    17581 agactaagta aaaagaaaca aagaggtgtt tacaatgggg ttgaaatttg aacgtacaga
    17641 taatttagat aaacttttcg aatcatttgc tgtcgatccg gaaaaaacag ttgcaccaaa
    17701 agaagagatc gatcgatttc taaaaccaca gccacaaaat gaaaagaaaa aagacaagaa
    17761 acaaaagtaa gttaagctca aaaaaagact taccagccaa acttttatga aagagtttga
    17821 ctggtaagtc ttttttattc tttttatgat tcaattgctt gttcgattgc tgcccacgct
    17881 tcttcttttc cctgttttgt aacggaagaa aagagaataa acgtgtcatt gcgatcaaaa
    17941 tccaacgctt ttttgatttc gctctcatgc ttgttccatt taccacgagg gatcttatct
    18001 gccttagtgg caacaacaat tacagggata tcataatact tcaaaaattg atacatctgg
    18061 atatcttctt gagaaggctt atgacgcaaa tctactaaag aaacgaccgc acgtagctgg
    18121 tctctagtcg ttaaatatgt ctcgatcatc tttccccatt ttgctcgctc agttttggat
    18181 acttttgcat acccatatcc cggaacatcg acaaaatgta atgcgttctc gatcaaataa
    18241 aaattcaatg tctgggtctt tcctggctta ccggaagtac gggctaaatt ctttcgatca
    18301 atcaatgtgt tgataaaaga agatttccct acatttgatc gtcctgccag agctatttct
    18361 ggcaattgtg tatctggata ttgttttggt gccactgcac ttatgataat ttcagcttga
    18421 tggactttca tggtctctct ccttaacaag gtgatgaata aagcaagcgg ctgtcgcaaa
    18481 agccaaaatg acttttacgg cagcctcttt tcatcaaccc gcttttttct ctgaatcttt
    18541 atagattact gttggctcac cagacaattc agctgcttct tttgtgataa tcactttttc
    18601 gatgttttca tttgaaggga tatcaaacat cacatccatc atgatttctt caatgatgga
    18661 acgaagtcct cgagcaccgg tattgcgttc gattgctttt ttcgcaatgg ctctcaacgc
    18721 ttcaggttcg aattcaagtt cggtattatc tagagaaaga agtttttgat attgtttgac
    18781 tagcgcattt ttcggctcag tcaagatccg taccagatca tctgttgtca atttctctaa
    18841 agctgccata acaggtaatc gtccgataaa ctcagggatc aatccgaatt ttagtaaatc
    18901 ttcaggaatg atatgctgca tgacactttc gtcttcagaa agtttttggt tttgtgtacc
    18961 aaatccaatc gtcttttcgc ccatacgatt cttcacaatc gtttcgatgc catcaaatgc
    19021 accacctacg atgaacaata tgttcgtcgt atcaatctga ataaattctt gatgtggatg
    19081 tttacgtcct ccctgaggtg gcacgcttgc aacagttcct tctagaattt tcagcaaggc
    19141 ttgttggaca ccttcgccgg aaacgtcacg agtaatagat acattttcgc ttttacgcgc
    19201 aattttatcg atctcatcaa tatagatgat ccctttttct gcacgttcca cattgtaatc
    19261 agcagattga agcaatttaa gcaaaatgtt ttctacatct tcccccacat aaccagcttc
    19321 tgtcaaactt gtcgcatctg cgattgcaaa aggtacattc aatgtttttg ctaatgtttg
    19381 tgctaaaaat gttttaccag accctgtagg tccgatcaag cagatattgc ttttttgcag
    19441 ttcaacatca tctgtgtttt cttgtgcttg ctgattgaca cgtttatagt gattgtatac
    19501 ggcaacagct aacgagcgtt ttgcgcgatc ttgtccaatc acgtagttat tcaatacttc
    19561 aagaatttct agtggtttag ggacttcagt gaattcgcgt acagcttctt cataaaattc
    19621 ttcatcaatg atttctttac ataggtcgat acattcatta cagatgtaga cccctggacc
    19681 agctacgatc tttttcactt cttcttgggt tttcccgcaa aaagaacagc gtacggtctc
    19741 attgctactt ggattgtcat acatggtctt caccccttaa cttgcaaaaa gtatgcaaga
    19801 aactatcaaa gactttacag tcttttacta tcataacata gtttagtaaa aagaaaaagt
    19861 gtttaacaaa ggatcaactg acctatacct ttgcattttt tactcttaac aaaaaataag
    19921 gaactgtgac aaaatcgtgt cacagtccct tatttcgaat aaacaatttt ctagaagtag
    19981 cttcttcaga aatgatttat tacttgattt ctattctttc gcttctgtcg ctgtacctgt
    20041 gatcaattcg attgcttttt tcattgtcac atcatgttcc agcatatctt ctgtcaacac
    20101 gcgtttgatt tgttcgattg gcatgttgta tgtttctgat aattcttgga tttctgcatt
    20161 gatttcttct tctgttgctt gaagattttc agcagctgca attgcttcga tcacaagatt
    20221 tgttcttgtg cgcatttctg cttcaccttc gaattgttta tgcaagtctt cttctgtaga
    20281 accagttaat tgatagtaca tttcaggaga gataccttga cgttgcatgt tgttcaagaa
    20341 ttcgtccatt gaacgatgta cttcatcatg aaccatcacg tgtggcaatt caacgatttc
    20401 tgcgttttca acagccatac ggatcgctgc ttcatctttt gcatcgtccg ctgctttttc
    20461 ttttgtttct actaattctt tgcgatattt ttctttcaat tcgtctaatg ttgatacttc
    20521 gtcatcaaca tcttttgcga attcgtcatc taattcaggc acttcttttg cttttacttc
    20581 atggattgtc actttgaaga ctgcttcttt tccagcaaga tcttctgctt gataatcttc
    20641 tgggaaagtt acatttacat ctagactttc acctgattta tgaccaacta attgatcttc
    20701 aaaacctgga atgaatgagc ctgaacctaa ttcaagtgag taattttcgc cttttccgcc
    20761 atcaaacgct tcgccatcta caaagccttc gaagtcgatt actactgtat cgccattttc
    20821 agctgcagca tcttctttga taactaattc agcttgtgct tcttgttcac gtttgatacg
    20881 tgcatccacg tcagcatctg ttacttcacg gtcttgtttt tcaacaacta gatctttata
    20941 ttgtcctaat tttacttctg gtttcactgt tacttcagca gtgattaccc agtcttgacc
    21001 tttttccatg ctttcaacat cgatttttgg ttgagaaaca ggatcgatgc cagcttcttt
    21061 gacagcagct tcataagctt ctggtaatac agcattcaat gcatcttcat ataaagcttc
    21121 ttcaccgtac atacggttga atacttgacg agaaactttc cctttacgga atccaggtac
    21181 gttcaagctt tttttcactt tattaaacgc agttgttaat cctttttgga tttcgtcttg
    21241 cgcaatcgta aattttaaaa caccatcatt cgtgcctttt ttttcaaatg ttgcagtcat
    21301 ttaattccct ccgagtttag aaattcattt tatacatcaa aaacgtttca tgcatacctt
    21361 taaatagtac actaaccctt tcaaattgta aacatattga atggatagaa tccttgtttt
    21421 tcataacatt tttatctttt tcactgataa aatctaatgg aagaagatca tttgctgcaa
    21481 aattttttct ctttttttta aaaaatcttg tttttcatct tctgtacctt catacatcgt
    21541 ttttcctgta cacgcctcta cagtcagttg aaaccagcgc ttcgggtctt cgatgtatgt
    21601 atcatagaca ggataaacaa ttgcagattg caacgtgaat tcttcattta acacggaact
    21661 aagcagcgca tcttcattac cgtaacgatc tgaaaataca cataattgct ggtaacttgc
    21721 ctgctgctgc ggctttggca gatcttttgg tatgactttg actaactttt cttcaatcgt
    21781 caaatagaaa acaggatggc attcgttcaa ttgcctaagt gtctccagta attttgccct
    21841 tgctaaaata tggacctctg gcgatacaat aagtttactc gctgtttgga taaactcatg
    21901 ataaggaagc tgttcgatct catcaataga cgcaagctga cgtgcaggtt ccaacgaagg
    21961 aagttcctcc gatttattgt ggagtgcctt gatcttctgc ctctccattt gtccggataa
    22021 ttcttctgca aattggattt tttcaatgac ccgctgctcg aaagcttcat aaaaatctgt
    22081 acttgctatc aattttctag catataaaaa atcttgtgta ctgattaaca agtcaaaata
    22141 aaattcagca aactcctcat tttgaagata ctgtttttca tgcaagagtg cttgcttcaa
    22201 tgcttctttt ttctcgtcca actcgtaaag acaaaaaaca agcaggctat tagcctcaaa
    22261 gctttctttc aactcgtaag ctcgttgaaa taattctttt gcctgctgat attgctggtt
    22321 tgctagtgct tgttgtgcta ctcgcattaa attctcatat ttttctggaa aatcaatcgg
    22381 cttcacgcag tgtcctcctc ttgctcatgt tcagctcatg ttcaatagta gcaaaacaaa
    22441 aaaagcatga caattaaaaa taactgaagc accctctaaa agctagattt tagatctgac
    22501 ttttagaagg tgctttcaac tgttactgct ttttattgct catcagctgt tgacttcctg
    22561 gttgaatgct ttgatcagat tgatcgtaac aacacttgta ttagtgaaaa aatcgcctag
    22621 atgttgcttt ttctgattaa agattgctgg aagataccct aacatcagca aaggaaattt
    22681 tagaatgaac cggcaagcac cttctctaac taaaacggtt gaccagctaa gttcttcttc
    22741 atcaaagctg atgactcgaa taccaaagat cattttccca atcgtttgac catgattgaa
    22801 tttcgtcaat aaaataaaat acgctagata aataagtaag gctgtgaatc cgtagatact
    22861 cagataagaa tctgaaaaat taagccaacc tagatttttg gcaataccaa gtgttaaacg
    22921 cgtaatagct ccgatacaca aaagatcgac caagaaagca aacattcgga taaaaaaacc
    22981 tgcatagaaa tacttaggaa aatcatttgc ttttggcggt tcatttcttg tgtccgtata
    23041 ctttttccat ttacgttgtt tctttttgat ttcttcgggc gtcaaaggct ctctttcaaa
    23101 agagctcagt accttttggg aaaagttgga gtcaggtcct acagcaggct gctgttgctt
    23161 atctttttct tgttccttat tttcatttga aagctctgac atgcttactc acctccgtaa
    23221 taatacattg cttttggtga ttccgctgtc cctagattct caagaacgga taagatctga
    23281 ctagtctcag aaggcttcaa tccctggaat tctgctagtt tacttcctaa ccatgtacta
    23341 gcaaacccag atggcgtgga agaatattct actagttccg catcttcaag ctgttgttcc
    23401 tttcgcatag cttttaaagc atcttcagga aatcccaatt catcgactaa acctacttct
    23461 tttgcttgga caccatcata aatccttcca tcagcaattt ttttgacttc ttcttcagat
    23521 ttattccgtc cctcgctgac gattgctaca aaacgactat atgcgctgtc gatatatgct
    23581 tgaagcaccg cttcttcttc ttttgtctct ggtcgcgttc ctgaacccat atctttcaac
    23641 gctccgcttt taactgttgt atcttccaca cccagttttt ctagaagtcc tgaataattc
    23701 aatcctgaca tgatcacacc aattgagccg gtcactgttt cttctgttgc aaagatttta
    23761 tctgcttgag cagaaatata gtagccaccg ctagctgcca tgtttttcat gctgacatac
    23821 attgggatat catgttcttt acgaatcgta tccaatttct tagcgatttc cgcactttcg
    23881 tagacaccgc caccaggaga atttacttct aaaaagatac ctttgactgt tggatcttct
    23941 tcaatcgcct tcagttgttc cataaaattt ttatgattgt aaccttcaga agcaaataaa
    24001 cctgaagacc ctcccgcagc aatcgttcca tctactgata attttacgat tttttgcgta
    24061 ctgtctccct cttccaacac atttgaagct agttcttcat ccccatataa ccaactgttc
    24121 aatccctcaa tttgatcgtt ttcctgaggc ttagtcaaac tagctgaaac taacgaaacc
    24181 acaaataatc ctgcagcaat cagaactgct gcccaacgtc tcttattcat tctttctcct
    24241 ttctaataca agttttttat gacgatcaca gtttctgact gctcagaagt gtcgaaccgc
    24301 tctgcttttt cttcccgcgc atacccggaa aacgactctt ttgtcaattc atcttctacc
    24361 gtaaactcac gagcttcagc aacttccaag gcatcaggtg cgatttcttg gatgctatcc
    24421 cagccagtat ctaaaaatat tttcgtatca tctgatacac cagctgatgc ttcgaatttg
    24481 gacaattgtt tttttaacat tcccagtgtc atgatctcaa tttttgaatc catttttact
    24541 cctcctctat ccgattactt tctattgtac cgaactcctg aaaaagatga tagataaaaa
    24601 cccattattt tttgacataa aaagggcatt tgacaaagca tttgatatat accaatttat
    24661 tttttattct ttttttgttg acaagaacat tcgcaaaagg ttatgatttt aaatgtttcc
    24721 agataaaaaa caaaagagga ggatagttat accttttagg atagcgccag gtctgtgtaa
    24781 acagatgacg aggagagggt ttatcgaaag attcggcgga tggccctagg gactgcactc
    24841 tacagaaaat ccacaaaaaa tatctgcaaa gataaaacaa aaggattttc ctgcagctgg
    24901 aagcattcat acgaattcat tatagaaagt aggatgtttt ttatgtgcgg aattgttgga
    24961 atgattggat taaaaaatgt aacaccagga ttgattgacg gtctagaaaa attagaatac
    25021 cgtggttatg attcagctgg tatctttgtc tcagatggca caactgatta tctggtcaaa
    25081 gcacaaggca gaattcaaaa tttgaaaaac aaaataaata ttgatactac aggaaatata
    25141 ggtattggtc atacacgctg ggcaactcac gggcaacctt ctgaagaaaa cgcccatcca
    25201 catacttccc aaagtggacg cttcgtgctc gttcacaatg gcgtaatcga aaactttgaa
    25261 gaacttaaaa ttgcttattt agcaaatgac cactttattg gtgagaccga tactgagatt
    25321 atcgctcatc taattgaaac tttcgcgaag gatactacaa cgcaagaggc gtttttaaaa
    25381 gctttgcggg tcatcaaagg ttcttacgct ttcgctttga ttgatcggac agcacctgat
    25441 gttatttacg tcgctaaaaa taaaagtcca ctattaatcg gactcggcga tggattcaat
    25501 gtgattgcca gcgatgcaat ggctatgctt gctcatacga aggaattcgt tgagattgaa
    25561 gatgaagaga tggttaccgt cacatcagaa aaagttatta ttcaaaattt tgcaggtgac
    25621 atcgtagaac gttcttcatt cgaagcacaa gtagattctt cagatatcga gaaaggtacc
    25681 tatccttttt atatgctgaa agaaatcgac gaacagccta ttatcatgcg tcgtatcgct
    25741 caaaaatacg taacagaaga caatcgtgtc tctcttgatc aaaagctggt cgatacattg
    25801 tctgatagcg atcgaatcta tatcgttgct tgcggaacta gttaccatgc ggggttagca
    25861 ggtaaacaga ctctggaaaa attgacacag atccctgttg aggttcattt agccagtgaa
    25921 tttggctata acacacctct tctttcaaaa aaaccattct ttattttctt gagtcaaagt
    25981 ggcgaaacag cagatagccg ccaagttctg gtaaaaatca accgtctcgg ctacccttca
    26041 cttacgatta caaatgttgc tggttctact ctttcgcggg aagcatcctt tacactgcta
    26101 ttgcatgctg gacccgaaat cgcagtagca tcaacgaaag cttatactgc acaaatagct
    26161 gtactaactt tattagccaa agctatcggt gataaaaaag aatttgaaac ttctcttgta
    26221 ttcgatatca ctcatgaatt gagtttagtt gctaatgcga tggaatcggt catcgcccaa
    26281 aaagattatt tagaagagtt ggcagaagta tatctcagcg atacaagaaa tgccttttac
    26341 attggacgtg gcgctgacta caacgtttct cttgaagctg ctttgaaatt gaaagaaatc
    26401 agttatatcc aggcagaagg ttttgccgct ggcgaattga aacatggaac gattgctttg
    26461 atcgaagaag gaacaccagt gattggaatc atcagtgaag aagtgactgg tgcgcatact
    26521 cgaggaaacc tgaaagaagt cgaaagccgt ggcgctaaaa cactagttat tgtctcagag
    26581 ggattagaaa aggaaagtga ccagctggtg ctaccaactg tccaccctta tctaactact
    26641 ctaaccacag tcgtaccgac tcaattactt gcatattacg caacgctatt acggggattc
    26701 gacgttgaca aaccacgtaa tttagcgaaa tcagtgacag tagaataata aaagaacaag
    26761 gaccagtgtc agacatctga cactggtcct tgttctttta ttttttatga aaatatctct
    26821 taatccagtc cgatttcttc tttgactact gccgcgattt tatcgacata gtaattaact
    26881 ttctcatcag taggcgcttc tgccatcact cgaagtaatg gttctgtacc ggaaggacga
    26941 actaggattc ttccttctga tcccatttca gcttctgcct cttcaatcac ttttttgatt
    27001 gccggaacat ccatcgcacc gtttttatca cttactcgga tattcactaa tttttgcgga
    27061 tagattgtta cctctgctgc aagctctgat aatttcttac ctgtctgttt catgatattc
    27121 agtaactgaa ttcctgaaag catcccatct ccagttgtgt taaaatctaa gaaaatcatg
    27181 tgcccagact gctcgccgcc aaagttataa tcgtttttgc gcatttcttc tacaacgtaa
    27241 cgatcaccaa cttgtgtaac gacatctttc aaaccgattc cttccaccgc tttgtggaat
    27301 cctaagttac tcatgacagt cgtaacgatc gtatcttttt tcaatcgatt tttttctgcc
    27361 aagtatttag cacagataaa catgatttta tcaccgtcga caatgtttcc aagttcatcc
    27421 accgcaataa tacgatcgcc atcgccatcg aaagctagtc cagcatctgc tcctttttca
    27481 acgaccatct cagctaaacg ttctggatgg gtagagccta cgccatcatt gatatttaac
    27541 ccgtctggat ttgtgcccat ggtataaaaa tctgtttcaa gatcggcaaa caaacgatta
    27601 acacttgttg aagttgctcc gtttgctgca tcgacacaaa tggtcaaacc ggaaaggtca
    27661 ccgttgatcg tttgtacaag gaattgagaa tatttcaata agccttctgg aaattcttct
    27721 acagttccca atccttcagc tgatggacga ggcaattcat ccacttcagc atctaataat
    27781 gcttcaattt ctagctcttg gtcatctact agtttaaaac catctgcacc gaaaaatttg
    27841 attccattat cttgtgctgg attatgagaa gcagaaatca tgacccctgc gcttgctttt
    27901 tgcaaacgtg tcagataagc aacacctggt gtagagatca cacctagctg gaacacttcg
    27961 atacccaccg ataaaagtcc tgaaatcagc gcttcttcta acatttgacc tgagattctt
    28021 gtatcccgcc ctactaacac gcgtgggcgt tttccttctt cttcatgctg gcttaggaca
    28081 taacctccgc accgtcccag cttaaatgca agttctggcg taagttcctt gttggcttca
    28141 ccgcgtacgc cgtctgttcc aaaatattta cccatagttg taaaattact cctttaactt
    28201 aattttctga ggaatttgtt ctgctcattt gtgttgattc gcttgtttct gatgtttctt
    28261 ctgtacttgt ggtcgagctg cttgtcccag attccgaact ggaagaaatg gttgttgtcg
    28321 atggttccgt tcctgaatca gcagatgaaa tacttctact cgtacttgta ttttcttgtg
    28381 tccgactgct cgtcgaagca gagctactgc ttgacgtttg caacacgggt gtaatctcca
    28441 cactaactga ttcgggcttg atacttaacc cctcttctac tggtatttca attttacgag
    28501 ttgttcgatg attgatacct gagacattga tcggtacagc aatactgtca ccgatcgatg
    28561 caagcaaatc gctagagccg cttacttctg cttccagttt tgaaaaactg aaatcatagc
    28621 tttctacccc ggcagctggt gttccttgct gtatcccata aagtcgtacc gacttgcttg
    28681 gcttgatcga atcagctctc actgttactt gcactggatc agagacgata cttaatactt
    28741 cccctgctgc attcagcgcc tgtattggga cctcactatt aatcccatca tctgtgacca
    28801 tcgaagcgtc cacatcagct actactcgtt tgatttctgc caatgttttg tcacctgtag
    28861 tgatagagac ttttttagga ctaacggaag tatcatcaag ttcatatcca gatggtgtga
    28921 acgttgaagg aatcaacgtt tccacatcga aatcttttat tacctttttc tcaaccgtta
    28981 ctgtaatagt cgatggttcg atctttgctg tgacagcact gctcaaattt tgaattttta
    29041 gcggaacctc atgtgttcct tcgcccagct tagtgatatc tgctgtgacg cggaacatcc
    29101 gtgtatcttc gtttgcctct gcattcaact gaactcggtt tgcactggaa agtttgacag
    29161 tcactgcatt ttcatatcca tggatatagt agcgctttga atcataagaa atcttgattg
    29221 gcaccccagt aactgtttga ttatacgctt catttccaga aagcgtattt ggaacggact
    29281 ggccatttgc attgaagtac agcgcaatac tgaacagcaa tgcaataaaa ctgtaaagaa
    29341 tgcttgtccg tttctctttt gagatcattt gcgatcccct cccttagtca taccgtctag
    29401 gaaagattga atcacgtttt tcttgttttt tgttttctct tcagcaatca gttctctacg
    29461 caaaattgcc aaatattctt gctgggataa gccagccatc agttcattat ctaatgtaat
    29521 gctgacatcc ccagtttctt cagagacaac gatggtaatc gcgtcgctga cttcgcttat
    29581 accgacagct gcccggtgtc gagtcccgaa ttcttttgga atcaacatac tttctgatag
    29641 aggaagatag gcgcttgcta ctgcgatctt tccttctttt acaataactg caccgtcatg
    29701 cagcggtgta ttaggaataa agatattgat cagcagctct ccagtgatat ctgcatctaa
    29761 tgcaattcct gtctcaatat actcatctaa tccagtatgc cgttcgatag taattagcgc
    29821 accgattttt cgcttggaca tatattggat ggctttgtca aaagacaaga tcatcttctc
    29881 atcttcctgc tgttcgcttt ttgattgttt gaaaagcgaa ctgcgtccaa gatgttccag
    29941 tcctctccgg atttccggct gaaaaatcac gatagcagct atcaccccgt acgtaatgac
    30001 ttggttcatc agccaagaca aggtgtgcag accaatgatt tccgctacga ttcggataac
    30061 aataaaaata gctacacctt tcagaagctg aatcgctttt gtgcctcgca gcagttggat
    30121 cagtttgtat acaagatacc agacaaccag aatatcaagt atgttcacca aaaaattcag
    30181 agagaacaag tcaccggaaa acatttgctg ccaatagtcc aaattaaaaa gttccccgat
    30241 ttgaaatgac ataaaaagcc tctcttctct tttgagattt cctctctagt atatcatatg
    30301 ttttaatttt agaggctgat ctgctcgtat ttttcttgag aaaaacgcat aattttcagg
    30361 aaaattgcaa gtatgcgttt tatttttctc tgcaataaat atttttaaac ttcagagaat
    30421 tattcattat attttttctg ttatttttcc tttttttctt ttgtagcttg ttccattttt
    30481 ttacgtcgtt ctgctctggc agctcttctt tcttctgctt caaggtccgt cgttttttct
    30541 tttctagtct taacgggtac atcgatagat tcctctggtt caagtcgttt cttgattttt
    30601 tctaattctc ccgtcagtgc agcatagttg taaaaacgtg ttttagcgtc ttggatagtc
    30661 ttttcaaata aagcttttgc aagatttgga tttgcgttct ctagcgagga aaagcgaact
    30721 tgtttcctca tgaaatcagg catagcagag aaatcaggtt ttttgtagtc caaagtcatt
    30781 gggttcttgt ttttttcgac cattgcaggg ttatatcgat ataatgacca atagccagaa
    30841 gaaacagctt cttttgcttc tttaagcgat tctttcattc caccaagcaa accatgtgtg
    30901 atacaaggcg tataggcaat gattaaagaa ggtccaggat acttttctgc ttcttcaaaa
    30961 gcctttatcg tctgcatttg attggcacct gaagcaattt gcgccacata aacatttcca
    31021 tatgtcatcg ccatcattcc tagatctttc tttgaagcat actttccact agccgaaaat
    31081 ttagcgattg ccgaagctgg tgttgctttt gaggtttgac cgccagtatt ggaatagact
    31141 tcgttatcca aaacaagaat attcacgtct gctccgctgg caagtacatg atcgatcccg
    31201 ccaaaaccaa tgtcgtaagc ccatccgtct ccaccaatca tccattggct gttttttacg
    31261 aatagatcct ttctcttgta tatatcctcc agttcaggga caattgatcg ttcgctttcg
    31321 atcgcagctt gcagttttgc tgctctttgc tgcgttcctt cgctctcaaa catgtgtacc
    31381 aaccagtctt ccatcaattc tcgtagttct tctgatactt ttggcaatac ttctttgatt
    31441 gaacttgcca aagcctcgcg acgagtctgt gccgctagaa gcataccata accaaattca
    31501 gcattatctt ccaataaaga atttgaccat gcaggccctt gaccacattc attggtcgta
    31561 taaggagaag caggagaagc accgccccaa atagaagaac agcctgtcgc attcgcgatc
    31621 atcattcgat caccgaacat ttgtgtcaat aattttacat aaggtgtttc gccacagcct
    31681 gagcaagcgc ccgagaattc aagaagcggt tgattgaatt gtgtagacaa gacagtattc
    31741 tttcctttga ctggatttgc tttttgtctt aatgtcattg caaaagccca attcacagct
    31801 tgttctttct gttcttcata aggcttcatc actaaagctt tttcttttgc gggacaagcc
    31861 tctacacaca gaccacaacc tgtacagtct tccactgaaa cttggatacg gtattttacg
    31921 ccgtctgcgc ctcgcatttc tctcacgata aatccttctg gcgcttcttc catttcctct
    31981 tcatctgcta aaaatggacg gatggcagca tgaggacaaa caaaggcaca ttcattacac
    32041 atcgtacagc gatcactaat ccactcaggt acttctaaag cgacgccccg cttttccata
    32101 gaagccgttc ctaaaggcat ttcgccagtt gtcattccat ttgctacaag tgtaccaaca
    32161 gagagttgat ttccttcctg tgcattcact ggttcaagta tttcttgtat ataaccagtg
    32221 ttccttttat tgattttttc aggcatctcc aacgttctcc aatggtctgg gatcgcgact
    32281 tgatgaagca gttcggtcgt ccgatcgatt gcttgtatgt ttttttctac gatagccatt
    32341 gatttatgtc catagctttt cagggcttct tcttttagca gcggaagcac ctcatcaaaa
    32401 ggaatgatgt cagctaattt aaaaaaagcc gtttccattg ccgtattgat ccggcgtccc
    32461 aaaccgactt cttgggccaa tctcatggca ttgatcgtat agaatctaat gttattttca
    32521 gccaagtaac gttttaattt taagggcaga tgcgtttcta attgttcgtc gctccaaaga
    32581 gtattcaata aaaaaatgcc acctggcttc aatcctttga ccaagtcata gctatgcagg
    32641 taagctggtg tgtgacaggc aacaaggtcc gcatgctcga caagatacgc tgaacgtatc
    32701 ggcgtatctc caaaacgaag atgagagaca gtcagaccgc cagatttttt cgaatcataa
    32761 taaaaatagc cttgcgcata tttatcggtg tgatctccaa taatcttgat agctgattta
    32821 tttgctccaa ctgttccgtc agatccaaat ccccaaaact tggcctggaa tgtttgcggt
    32881 tctgtcaaat ccagactttc ctttggttcc aaagattgat aagtcacatc atccacgatc
    32941 cctatggtaa accgtttttt gcgtatgctt gggtcttttt tcaattcatc aaaaactgct
    33001 gagatttggt cgggagtcac atctttagac cccaatccgt agcgaccacc aataacagcc
    33061 gggcgaagtt cagaatcata taacgcactt tgaacgtcta ataagagagg ttctccacct
    33121 gcccctggtt ctttacttcg atcaagaaca gcaattgttt ttactgtatg aggcaacttt
    33181 tgcacgaatg tttccactgg aaaaggacga taaagatgga tattcaaaaa acctgttttc
    33241 cgtccgtttg cattcaagta atcaatcgtt tgttcaatcg tctgtgcaac tgatcccata
    33301 gaaacaatga cttcttccgc atcgtctgct ccgtaataag tcaccaagtc ataagaagtt
    33361 cctcgtaatc ggttgatctc tttcatatat ttttgaacga tttcaggtaa tttatcataa
    33421 taggggttga tcgtttcccg ttgttgaaaa tggatgtctg gattctggtt cgtaccacta
    33481 acagtcggat gattgggatt catccctcgt ttacgaaatg aagctaattt ctcctgattg
    33541 atcagaggag ctaattcttc atattccaaa acttcgattt tttgaatctc gtgactcgta
    33601 cggaatccat caaagaaatt caaaaaaggt acttctcctt caatagaagc aagatgggca
    33661 acaggtgcta aatccatcac ttcttgtaca ctgctttcag ctaacatagc aaatcctgtt
    33721 tgtcttgcag ccatcacgtc tccgtgatct ccgaaaatat tcaacgcatt tgtcgtcact
    33781 gcccgactag caacatggaa aacacttggc agtagttccc cagcaatctt gtacatattc
    33841 ggtatcatca aaagcagccc ttgagaagcg gtatatgtag ttgtcagtgc accagttttc
    33901 aatgatccat ggaccacacc agctgctcct gcttcggatt gcatttctac tacttttact
    33961 ggttgaccga atacattttc ttttcctgct gctgaccatt gatctactaa ttcagccatg
    34021 gtcgaactgg gtgttattgg atatattgca gcaatctcgg taaatgcata agaaatatat
    34081 gcggctgccg tattgccatc cattgttttc atttttcgca tgattcatca tccttgttca
    34141 tattctctct tattatctgt tccattataa cgtaaaacat tccatttttt cttttattta
    34201 taaaaatatt tcacatatgt ctatttgaat tggtcatcta atttttagac aaacagtcta
    34261 aatcgttgcc tttttttgtc agacatgtat aaactataag cgaaagaggt gttttaacat
    34321 ggatatatca gtgattgatg caacgaaaac aaatacacaa aaaggaatcc tttatggttc
    34381 atcgaatgct cctaaaaaaa tggtcgaatt catcaaccta tcttgtccgt attgccgaca
    34441 atggtttgaa gaatcttatg agctattaga agaagcagtc caaagcgggc aattgcagcg
    34501 agtgatcaaa ttgttcgata aagaaaaaga aagcttgcag cgaggaaacg tgatgcaccg
    34561 gtatctcaca atcagcgatg gtcaaaaagc gatcaaagag atcaaacaaa tattcgatac
    34621 tcaagacgag tggaaacatc tttctctcca agaagtagcg gattttgcag tagataaact
    34681 aaagctgaca gaacaaaaag acgaacagct gagccaagct gtcatcaacg aagctgagca
    34741 agcacatatt cgatttgttc cgactgtcat cttgggtaaa gaaatctttg atgaatctat
    34801 ttcaatagag gaattaaaag aattgatcca aacaaaataa aaaaataagg agcgtaggac
    34861 aaaagtaaag aacacttttg tctcacgctc taaacaccta taaacggcgg aagcagaagc
    34921 aactccttct tatttcttgg agttaaacgc ttctgtccca gcctccttat tccgaataaa
    34981 tggtgtccaa aagcttgcat ctgccagatt atctcatttc ttatgacaag ctgagcaaat
    35041 tatctccacc aaataattta ttcatatttt tgacttgcgc atactaacta attcttaaat
    35101 tttcatacaa aatttctcaa attcccttaa cgagtaatat ttatgtacgg tgattcacac
    35161 tagtatccca atcacttttt aagttatccc gatttcaatt ctacttcaaa aatagttgct
    35221 tttatgtatg ctgttagttg attagatggt cgtttgttga gctaggtcgt ttattttaaa
    35281 caagttgttt ctttagctta tacctatctc gtctaccaaa cgcaagatgg caaacacaaa
    35341 tgcatacgca tctgtatttg ccactttgat tcgtataaag ctaacaactc ctaactcctc
    35401 tcatttaata gttgctctct tttttattca gatacatttt tgctgatcac agcctagtat
    35461 ttcaatggtt ttgaacacta aaccaaattg ttccattaca acattcactg gctgatgaaa
    35521 tggattaata gatttcgatt attcaaagcg attttctatt ggtggattgt gttcccaact
    35581 aacaagacgg attccaaagt cattatataa ctcttcaaga gttaaccctt tcctgttccc
    35641 aatagatgta tctctcccac gctcgatata aaatatggag tttcgaatgc caagacctgg
    35701 caaatctttc cttgttacag ttacactgct actaacttcc ccatataaaa tccagctcct
    35761 ccaaaatgat aatatatttt tcgaccatca tctaactcat gtaacaataa ttgttgtgcc
    35821 ctcttgtcac tcgccaaatg caaacgccac gtgcgatacc atgccatgct acctgcatct
    35881 gcagaaaatc catcaaataa tgcaacaatt gtatcttcta tcacaatcct ttccccatct
    35941 acttcatatt ctaatctaaa atcaaactcc cctcgggtaa tcgcaggtct tggtggctta
    36001 ggacccaata ttattctact taaaaccgca ttcgttccca gatgaaacac agctataaca
    36061 acaataatga ttaatatttt gtttctattt gataaatttc tcattattcg caaatcacct
    36121 ctacattctc acatactagt tcgtaatact cctttaatat caaaatatct actgatcgta
    36181 ataatattcg ctatgaattc ctactactcg tataagaaag gccaaatcat cagcttttac
    36241 ttgctgatga tttggcttgt ttctatttat cgtaattgtt ttctaatcac caaaattgtt
    36301 aacaatcggt tcagatattt cccaattcac tagccttata ttatattgat ttaacaattc
    36361 ttcttcattt attgtatttt gatcaagcgg accaaattgt tctaataatt ctttgtcatg
    36421 taaaatatcc cttctagtaa tgcctctttc cctttcaatg aaagaagcac taggaaaagt
    36481 atgattataa ccattcaacc tatctcccat gtaataatta gcaggtcctg gaaaataaaa
    36541 tatttgctta ttatcactaa cttctaacag caacactaaa tcttctccgc tggctaaacg
    36601 acttgtccat ctacgatatc tccctatgcc ttcgttcatt ccaaatccat caaattcaac
    36661 tattaacgtg tcttctatca catgtaattc ttcattcaat tcatactcaa gtctaaaagg
    36721 aaattctcca tatgtaatct ctggcaatgg tggtgctgga gttctccaaa taaatacaat
    36781 aactgtgaat agaaaaaatc caacgatcga tataaatgtt atgagacctg ctcgaagtaa
    36841 aacccgatat aataaaaatg ctgtatttcg ctttgctata tctagaaaaa taaaaagtac
    36901 tgcaatcata atgatagtaa aagttgtaaa aaaacgcatt tttgccctcc ctttataaac
    36961 atcgattctc aaattctaaa ccaaatcttg gtagttcaag ttcaggtata acgtattcca
    37021 accatacatc tcaattacta tttatgaact tatgattatc actgaataaa tcactccatc
    37081 cccttgttaa aacttctaca ttaattacac ctggttgttt tcgactagct aatccaatga
    37141 acttatcaac catccttatc caccaaccac gagaatcttg accagaagta agaagagcag
    37201 ttctcaagga tgatcgagca gttccttcca gttttttaat taatcaggcc agttatagat
    37261 aaatacttga tcttatctat atcaggactt ctatattaag caaaaattta tgtacaaaac
    37321 taaaatcttc attcagttgt ctccccgctt tttatacgat tgtattaaaa acaatagaag
    37381 cctttccaaa ttatgttact ccagtaaaga tggaattata gtttgacgga agaaaagcaa
    37441 gtataacttt taaaaaaaac tgatacattc gcatctcctg cttcatgtat cagttttttc
    37501 tttggattaa actgcttctt cacgcagttt ttccgcaaat tcatttattt tgcgaattcg
    37561 gtgattaatt cccgattttg atatcgcacc tgagggaatc atttccccta attctttcaa
    37621 gctgacctct ggatgttgaa gccgaagttc tgcgatttcc tgaagttttt caggaagggc
    37681 atgtagaccg acctttgctt cgatcaattc gatgttttcg atttgtttag aagccgcatc
    37741 aatcgtcttg ttcagatttg ctgtctcaca attgactaga cgattgaccg aatttctcat
    37801 atcccgtacg attcgaacat cttcaaatcg gagcattgag ttggttgcac caatcaatgt
    37861 taagaaatca gcaatttttt ctgctccttt taaataagaa atatagccat tgcgccgttc
    37921 aagcgttcga gcatgtagac cgtaataatt taacatatcg caaatgtctt ggttatgctg
    37981 ttcataaata gaaaatattt ccaaatgata acggctcgtt tccggattat tgactgaacc
    38041 tgaggccata aaagcaccac gtaagtaaga acgcattttt tgcgaatttc ccataatctc
    38101 gtccgaaacg tgtccattga acatcatacc atccatgata tcaagatcca tcaacacatc
    38161 ttttgtgcct tgcttcaacc ggacgatata gacattgttc ttttttaatt tcattttttt
    38221 acgaacgagt agctcacttc gtacctgata atgatctttc aaaagagaat agatacgtct
    38281 ggcaattgca gcattttctg tttggacgtt caaaataaac tgctggttca caatacctaa
    38341 agagccgttc attcgcagca aagcagctaa ttccgctttc gcatgttctc gatgaacttc
    38401 caaaccagtt agttctttct tcacatctgc agcaaatgac atcctattct cctcctttct
    38461 ccaacaataa attgcttaat attttgaacc gaaaactaaa cggaacaatt cttctactac
    38521 tttgtctcca tcgtggaaga caccaccatc tttcaattcc aaaaagtcgg tggaaatcac
    38581 tcgacatcct tcatttctca atccgttgaa gtcgtgtgcg acttgtacta gatactcatc
    38641 atagatctct gggtccatat aatcttcagg cactttttcc gtattgacca atactgtatc
    38701 gataaaaggc tgattcaaat gcttgtgtaa aacacgtata tgatcggcat ctgtgaaatg
    38761 ttccgtttcc cctttttggg tcatgatatt acagatatag acggtttcag cagttgtctt
    38821 gagcattgct tcgccgattt ctggtatcac taaatttgga aggatactgg tgaataaact
    38881 tccgggtccc aaaacgacca tgtcggcgtc cataattgct gaaacgactt ttcgagccgc
    38941 tttggcttca cttttatcat ttgtgttgca gacatacaca cggtcaatgg ttttacggtc
    39001 gatcgcgatt ttagattctc ctactgcagt cgttccgtct ttaaagacag catgcaaggt
    39061 caaaggagtt tctgaagaag gataaacatg tccatctaca tgcatcattt ttgctaataa
    39121 ttgaatcgcc tcataagtgc ttccccgcat ctcggaaact gcggcaatga tcagattacc
    39181 gatcgtatga ttggctaaaa actgatcttc ctttttgaaa cggtattgga aaatatcttc
    39241 atagaattgt ggcatatccg ataacgccac taagacattt ctcaagtcac caggaggagc
    39301 catagcgatc gattctctga ttgcaccgct gcttccccca tcatctgcaa cagtcactac
    39361 tgctgtgata tctgctcctt gatttcgcaa acttttcagg ataactggca gaccagtgcc
    39421 accgccgacc actacgatct ttggttttct tatccggtag gttttcattt tcacgaccgg
    39481 ttcaccgtct ctttcctttt atccttgtcc cgatgtgtca cattgacttt atagtttttc
    39541 cctaaagcat ttgccaaacg ttcagtcaat gccacagaac ggtgttgacc gcctgtacag
    39601 ccgattgcaa ctgtcaagct gctttttcct tctttaatgt atccaggcaa tacagtttcc
    39661 agaagatcca aaaatttatg gtagaatgat tgcgtttcat caaaggacat cacataatca
    39721 tagactggct gatcttttcc ggtcaatggt cttagttccg ggatataatg agggttgggc
    39781 aaaaaacgca catccatcac aatatccgaa tcgatcggca acccgtattt aaaaccaaat
    39841 gatacaaatt cgatccgaaa tccttggtct ccctttgatt tgaatgactc attgattttt
    39901 tcacgtaatt gtcgtggtgt caatgtcgtc gtatcaatga tcacggaagc ttgggctttc
    39961 aagtcgtcta gtatcgcccg ttctttacgt atcccttcag tgatcaaacc gtccatcgcc
    40021 attggatgtg ctcgtcttgt ttctttgtag cgagccacta gttcttcgtc tgaagcatct
    40081 aaaaataaga tagaagtgtc gatgaagttc gtattttcga tttcgatcag catgttttgg
    40141 atttcttcaa agaaggaacg agaacgtaaa tccactccta aagccatttt tgtgactttg
    40201 cctgattctt tgattaattc ccagaatttt ggaatcaatc gaggcggcat attatcgata
    40261 caaaaatagc ccatatcttc aaaactttgg atagctactg ttttccctgc accgctcata
    40321 cctgttatga tgactaattg caaattatct gtcataatta cgaactcctc tcacattgtg
    40381 catagtaaaa ttatatcatt ccgggcgtat cattaccagt tttctttttc ttttacaaaa
    40441 agatttggac caaatatctt ttaggatatt tgccccaaat ccaatttttt tacttttccg
    40501 atgctgtatc caatgccttg cttctttcag ctagcgctcg ttcaatcgtc cgatctgcta
    40561 aaatagattg ggcatcgatc actggataat ggttatcttc agcaaattca tgcatcaatg
    40621 acaattctgt gcaacctaag ataacttttt cacagtttag gcgctctacc gcttcttcta
    40681 agatttcgta atatagctct tgattcaaat aatccgattc cttgatctca tgatagatca
    40741 gataattgat tttttcttga agaacagtat caggaatcac tgtttcgaat ccaagatttt
    40801 tgacttcgcg ttcatagatt ccagctttca tacttccttc tgttcctaga atcgctactc
    40861 tccctgtcgt atgctgacgg acaagttcat ttgctgcttc tcttggcata tgaaggatag
    40921 gaatatccgt tgccgcttgt aattcttcaa aaaagtagtg tgcggtgtta caagtcaaca
    40981 caatgaagtt cggctgcaat aaattttgtt tctcaatatc atccagcaga aacggcattg
    41041 gattttcttc tgatcgatct aaaatataag ctgtacgatc aggaactgtt gcatgattga
    41101 ataagacata attcaaatat tcttgatctt ttgtagcttt cgttcggtgg ttgatcaagc
    41161 gaacaaaact ttctgtcgcc atcgtgccca ttccgcctaa aatactgaaa aaattctcca
    41221 tgaactagcc ttctttcaca tgaaaatact ttttgaatct tggaatatag ttatggaaca
    41281 tatatttcat caacaaccag cgcttgattg accggtcttt ttcataaaac acagtagtac
    41341 cgtaacgatt ttctttgatc atttgctcag ctagtttttt gtcttcattt tcccgagcat
    41401 attctaaaaa gatttttttg ggcacaccca tccataatct tgctttatct gattgattcg
    41461 ttccataggt cgtttcaaca aagggtttgt taaacactcg atcttctgtg acgaaacgag
    41521 ccagattcaa gccgttcaat gtcacaaaga aactgctacg accttgtctc aaattgattt
    41581 caaataattt atattctcca tctctaggat catacttcat atcgaaattg gcaaagcctg
    41641 tatattcgat tttttccaaa aatgccttaa tggtttgata gattttttcg ttataatctg
    41701 gcatgatcac aacgtaatta ccaatcgatg ctggtgtagg atcttctaac agtggatgac
    41761 caagacacat catccgaact tgatgatctt catctacata cgcatttagc acacgcatat
    41821 tactatcatc acccgggata aaatcttgta caatcatttc acttttataa ccggcttcgt
    41881 atatccggcc taaaattaaa tcgaactctt ctctagtctc taaaataaaa gctttttttc
    41941 ttccttcaaa ttggacagaa agatactcca cactgtttgc aggtttcaaa gcaactggga
    42001 attcaaaagg caattcctgt tccaaatgtc catttactaa catttcttct ctgacgatca
    42061 atgttttagg atacggaaga tcatattctt cacaaacttc ataaaagctt actttattga
    42121 tcagtctttc aaataaagaa taatcaatat atggacagat aaaatattct gacagctctt
    42181 gtttatgttg ggagatcaat tctgcatatc catcaccaca agcaatcaaa agatattttt
    42241 tactcttatc agaatatctt tcttttgcca aacgaagcat cgtctcgata aacacagggt
    42301 ctttatcaaa tcctggaata acttctacat tgacaatttt actgtagcgg gtaggggcta
    42361 actgatccga agcatatgct tggcagattt tgccgtatgc ttcattaaaa gaacgtgcca
    42421 taccataaac gttcatgtcg cttcctaata atatagggat aaattcttca ttttcaatac
    42481 tgttcatcat tatctctcac ttactcataa tctcttgttt ttcttttcca actacacaag
    42541 gaatatcata ccataaagaa aaaagcaatc aaaggaaact cctccgattg ctcaattctt
    42601 ttttgaacgg attgaactta taggaagttt ttgtctatac caatcagtgt agaaagaact
    42661 accatgtaat gattctagaa cactgatatt aataaaacaa gcaaaaattc atttttttat
    42721 gtttttttaa ctatctcagc tatctatcct ctttatacca ttattttttt caaatagtga
    42781 cctgtataac tttcttttac gttaatgatt tcttctggtg ttccagtcgc aaggatcgtt
    42841 cctccacctt ctccaccttc tggtcctaaa tcaatgatat aatctgctgt tttgattaca
    42901 tctagattgt gttcaatcac taaaactgtg ttaccagcat ctactaatct ttgtaataca
    42961 tgcaacaagc gggcgatgtc atcgctatga agtcctgtcg ttggttcatc tagtatatag
    43021 aaattctttc cattagagat tttgtgcaat tcactggcaa gtttcatccg ttgtgcctca
    43081 ccaccggaca atgtcgttgc tggttgcccc atcgtcacat aacctaagcc aacatcaaca
    43141 atcgtttgca gtttgcgatg aatctttgga atgtgcttga agaattctac agcatcttct
    43201 actgtcattt ccaaaatatc agcaatgctt tttcctttgt aatgcacttc taatgtttca
    43261 gagttatatc gtttgccatg acatacttca caaggaacat agacatcagg caaaaagtgc
    43321 atttcgatct taataattcc atccccgcga caagcttcac aacgaccgcc ttttacgttg
    43381 aaactaaaac gccctttctt ataaccccgc atttttgcct cgttcgtttg agcaaataac
    43441 ccacggatat catcaaatac acttgtataa gtcgctggat tacttctcgg cgtccggccg
    43501 attgggcttt gatcgatatc gatgatcttt tcgatacttt cgtagccgga aattgtcttg
    43561 aatttacctg gcttagcaga attcttattt aatttttgcg ctaacgattt ctttaagata
    43621 ctattgacca atgtactctt tccagaacca gacacacctg tgactgctac aaattctcct
    43681 aatggaaatt caacactaat atttttcaga ttgttttctg aagcaccagt gatcttgatt
    43741 gctttcccat tacctttacg gcgttctttt ggtacaggga ttgatttttt ccctgaaaga
    43801 tatttccctg tcaaagaatt ttcatcatta gctacttctt caggagtgcc tgcagccacg
    43861 atttgtccgc cttgttctcc ggccccaggt ccgacgtcaa tcagataatc tgctgcccac
    43921 atcgtatctt catcatgttc gactacaacg agggtgttgc caagatcacg cattttcttt
    43981 aatgagccaa tcagtcgatc gttgtcgcgt tgatgcaatc cgatcgatgg ttcatctaaa
    44041 atatacaaaa ctccagaaag attcgatcca atttgtgtag ccaatctgat tcgctgcgct
    44101 tctcccccag ataatgttcc ggaagcgcga ctcaaagtta gatagtctag tcccacattt
    44161 tccaagaatg aaagtctgtc atttacttct tttaaaatcg gtttggcaat tactttctct
    44221 tgttcagata acgttaagtt tgagaagaaa tctactgctt tttgaataga caactcattt
    44281 gtttgcccga tattcgttcc attgatttga acagatagag cttggggatt caatcgataa
    44341 cctttacatg tctgacaagt taattctgtc atataaagac gcatttgctc acgcgtgaaa
    44401 tcactgttcg tatcatgata acgacgctcg atattcttca ataccccttc gaaagtcgtt
    44461 tctacatcgc gaacgccacc aaaatcattt tcataatgga aatggaaaag atcatctgtc
    44521 ccattcaaga tgatatcctg atgctcttcc ggtaattctt cgaatggtgt atctaaatcg
    44581 ataccgaaac tttcacaagc ctgcgctaac atttgaggat aatactgaga gctgattgga
    44641 ttccatggaa cgatagcacc ttgactaagt gtcttcgttc tatctggaat cactaaatct
    44701 tgatcgactt ctaatttgac acctaaacca tcacagtctg gacaagctcc aaaaggcgca
    44761 ttgaatgaga acagtcttgg ttctagttcg ccaacagtaa atccgcaata aggacaggca
    44821 tagtgttcgc taaacaacat ttcttcttca ccgatcacgt caaccagagc atagccgtct
    44881 gccaatcgca gagccgcctc taaagaatca aatagacgag aacgaatccc ttctttcaca
    44941 atgatccggt cgatgacgat cgcgatatca tgttttttgt ttttctccag ctcaggcact
    45001 tcacttaaat catagatctc accatcgact cgaacgcgga cgtatccctc tttttggatt
    45061 cgttcgaata tttttttatg ttgtcctttt ttctttacca cgatcggtgc caacacttgg
    45121 atctttgtgc gctcaggcaa agccattact tgatctgcca tttgatctac tgattgactg
    45181 gtaatctcga tatgatcgtt gggacaaatc ggatgtccta cacgtgcaaa caacaagcgt
    45241 aaatagtcat tgatttccgt cacagtacct actgtcgacc gaggattttt acttgttgtt
    45301 ttctgatcaa tagaaatcgc cggactcaat ccgtcgatgc tatctacgtc cggcttatcc
    45361 atttgtccta aaaactgacg agcataagca gaaaggctct ctacgtatct ccgctgccct
    45421 tcagcgtaca gcgtatcaaa tgctagggaa ctttttccag aaccggacaa acctgtaacg
    45481 accacgaatt tatctcgtgg aatcgttaca tctatatttt tcaagttatg ggcacgtgca
    45541 ccgtgaatcg taattttatc gttagccatg ttgtcctcct actttgaagc ttttaattct
    45601 aaaatcatat ctcgcacatt agcggctgtt tcaaaatcca atgctttcgc cgcatttttc
    45661 atttcttttt ctaatttcat caataacgta tctttttctt ctttcgtcat ttcttcatac
    45721 gagacttgta ccgcttcttt tgtatcatct tccgattctt tcgtaataga aatcaaatct
    45781 cggatttctt taatgatcgt ttttggaacg atcccatgtt cttcattgta cttctgctga
    45841 atcgtacggc gtcttgatgt ttcatccatc gctagacgca tagaatctgt tactttgtct
    45901 gcgtacatga ttactttacc ttcttcattc cgagcagctc gtccaatcgt ttggactaag
    45961 gaacgttcac tacgtaaaaa gccttcttta tccgcatcca agatagcaac aagggaaact
    46021 tcaggtacgt ctaatccttc acgaagcaaa ttgattccaa ctaacacatc aaattcacct
    46081 aatcgaagat ctcgaatgat ttctgttcgt tccagcgttt tgatatcact atgcaaatat
    46141 ttgactttga tccctaattc tttgaaataa tctgtgaggt cttctgccat ttttttcgtc
    46201 aatgtcgtta caaacacccg ctggtctttt tcgactcgtt catttatttc gcctactaga
    46261 tcatcgattt gtcccatgat tggacgaact tcgatcactg ggtcaagcag ccctgtcgga
    46321 cggatgattt gttggataac ggtatctgtt tgttcatgtt catatggtcc tggcgtcgca
    46381 gagacataaa tgatctgatt gacatgtttt tcaaactctt ctaaccgaag tggccgattg
    46441 tctaaagcag atggcaaacg gaaaccgtaa tctactagca tctgttttct cgctcggtca
    46501 ccattataca ttcctctgac ttgaggcatg gttacgtgcg attcgtccgc cacgatcaaa
    46561 aaatcttcag gaaagaaatc caatagcgta taaggcggtt caccttcttt acgtccgtcc
    46621 atatgccgag aataattttc aattcccgac gtgtagccca tttctaacat catttcaata
    46681 tcgtaattgg ttcgctgttc taaacgttga gcttccagaa gtttgttttc atttcgcaag
    46741 acagttaaac gctgttctaa ttccgctttg atattcgcta cggcatgctc catatgttca
    46801 tcattcgtca caaagtgagt cgccgggaag attgccacgt gttccgtttc tcctaaaact
    46861 tcacctgtca gtgcattgac ttctcggata cgttcgacct catctccaaa aaactccaca
    46921 cgtaaggcac gttcatctct tgaagccgga aaaatctcca cgacatcacc gcgcactcga
    46981 aaacgaccgc gctgaaaatc tatatcattt ctttcgaatt ggatactgac taagtcacga
    47041 atcaactgat tgcgatctag ttctgctccc tgtcgaatcg aaactacttg tttttggtac
    47101 tcaaaaggcg aacctaatcc aaaaatacat gaaacggatg caatgacgat cacatcattt
    47161 ctttctaata atgaactagt agccgaatgt cgtaatttgt cgatctcatc atttacactt
    47221 gaatcttttt cgatatacgt atcgcttgaa ggcacataag cttcaggctg ataataatca
    47281 taataagaaa caaaatattc aacagcattg ttagggaaaa attccttgaa ttccccgtac
    47341 agctgaccag ccaatgtttt gttatgggca ataattagtg ttggtttatt cactttctca
    47401 ataagattgg aaatcgtata tgttttccct gttccagtcg cacctaataa gatttgtgct
    47461 tttttcccgc cgactacgcc atccactaat tggttaatcg cttcaggctg atcaccagcc
    47521 ggttggtatt tcgagacaag ctcaaagtgt cgggaggtat ctctctcaat cattcttcgt
    47581 cctccttttc attcattcct tttcatttta cgaccaataa aaagaaaagg aaagcaaagg
    47641 cattccttac taaaaaatta taccacaccg aacatacttt cgccactttt ttatcttatt
    47701 atgcatgtta cgttttataa cataaaatgt tagaaactcg catttttttc attttttcga
    47761 gcttacagtc ttgtctgatt cagcactttt cgcctataat aataaaatat tggaaattta
    47821 ggaggttgat tatgaaaaga aagcatttat ttcactcatt tgttttctta atgacaggac
    47881 ttgtgacact tgcgtttgga catgttgcac aagctgacaa cactacaacg gcagagtcaa
    47941 gcacaagcga gacaatgcaa aaaatagagc ccaaaaaaga cgtatacgta attgccagtg
    48001 actctgcttt tgctccattt gaatttcaaa acgcaaaggg cgagtacgaa ggcatcgatg
    48061 taaaattgat ggaaaacatc gccaaactgc aaggatttaa catccgaatg gactaccgtg
    48121 gtttctctgc tgctttgcaa gctttggaat caggacaagc agacggaatg attgccggaa
    48181 tgactgtaac agatgaacga aagaaaagct atgatttttc tgattcttac tttgatagcg
    48241 ggatccaatt agctgtcaaa aaaggagata cttcgatcaa gtcttatgaa gatttgaaag
    48301 gaaaaacagt cggagcaaaa gttggtaccg aaagtgctga atttttaagc gaccatgaat
    48361 ctgaatatgg ctattctatc aaatattttg atgctgctga tcaattgtac gacgggttaa
    48421 aagttggcgc aatcgatgca atgatggatg attatccggt aatcggttat gcgatcaaac
    48481 aaggacaaga attggaaaca ccgatcaaaa aagaatctgg cggaaaatat gcatttgccg
    48541 ttaaaaaagg acaaaatcct gagcttctta atatgttcaa tgaaggattg aaagaattaa
    48601 aaagaacagg cgaatacgat aagattatta aagaatatgt agcggatggt tcagaaactt
    48661 ccagtgagtc ttccactgct gatgaatcaa catttcttgg acttatccaa aacaactatc
    48721 aagcattgtt gaaaggactt tggagaacaa ttctcctaac tttgatctcc tttgctttgg
    48781 ctatagtaat cggtgtgatt tttggattat tcagtgtagc accaatacgc gctcttcgca
    48841 caattgctag tatttatgtc gatatcatcc gaggaattcc aatgatggtt cttgcgttct
    48901 ttattttctt tgggttgcct ggtatcgttg gatttacgat tcctgacttc cttgctggtg
    48961 ttatcacctt gactcttaac gcaagtgctt atatcgcaga gattgttcga ggcgggatca
    49021 acgccgttcc tgtcggacaa atggaagctt ccagaagttt aggtctttct tataatcgga
    49081 caatgcaaaa aatcattttg ccgcaagcga tacgcatcat gatcccatca ttcgtcaatc
    49141 agttcgttat ctcattaaaa gacacaacga tcatttccgc aatcggtgta gtcgaattgc
    49201 tgcaaactgg taagatcatt gttgcacgta caacacaaag tacgtatgtt tacttgatca
    49261 ttgcgatcat gtacttgatt ttgatcacag cattgacaaa attagcaaaa gttttagaaa
    49321 agaaggtgaa gtaagatggc agaaaaaatc ttagttgagc atttagtcaa aaaatacggc
    49381 gataacacag tattaaacga catcaatgtg tccatcaacg aaggagatgt cgtctgtatc
    49441 attggccctt caggttcagg aaaaagtaca tttttgcgtt gcttgaatcg tttagaagaa
    49501 ccttctgacg gtgaaattat tattgacggc gcccacttga tggataaaag cacagatatc
    49561 aacttggtga gacaacatat cggaatggta ttccagcact ttaacctatt ccctcatctt
    49621 tctattttgg aaaacatcat tttagcaccg atggacctga agaaagaatc tagagaagaa
    49681 gcagagaaaa aagcaatcaa attgctgcag acagttggtc tagaagataa aaaagatatg
    49741 tatcctgaaa tgctttccgg tggacaaaag cagcgtgtgg ctattgctcg tgctctagcg
    49801 atgaaccctg acatcatgct ttttgatgag cctacatctg cactcgaccc cgaaatggtc
    49861 ggtgatgtct tgaacgtcat gaaaaagtta gcagaacaag gtatgacgat ggttatcgtt
    49921 acgcacgaaa tgggcttcgc taaagaagtg gccaatcgtg tcatgttcat tgacgacgga
    49981 aactttttag aagacggaac gcctcaacaa atctttgaaa atccgcaaaa tgaacggaca
    50041 aaagatttct tgaataaagt attaaatatt taataaaaac caaaaatgcc cggtcgcttc
    50101 atgacgaccg ggcattttta gtttcttgtt ttttcactta actgtaccag ccgcatcgct
    50161 tgttctcctg cacaaacaag caatcgctct acctgttcca tcgcataaga aagtaccatc
    50221 ggttcattga cgatatcaag tacatagtcg ataccacctt cagaaactat gatgattatc
    50281 ttattctaaa gctggctttt ttgttggtac aaacatgaca actacaaaaa aaccaggcga
    50341 acgtatgatt
//
LOCUS       DBGZHO010000012        45832 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.012, whole genome shotgun sequence.
ACCESSION   DBGZHO010000012 DBGZHO010000000
VERSION     DBGZHO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.012"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            316..1185
                     /locus_tag="ACN3HL_000908"
     CDS             316..1185
                     /locus_tag="ACN3HL_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8005802.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1394..2419
                     /locus_tag="ACN3HL_000909"
     CDS             1394..2419
                     /locus_tag="ACN3HL_000909"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HHC8005803.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2458..3408
                     /gene="manA"
                     /locus_tag="ACN3HL_000910"
     CDS             2458..3408
                     /gene="manA"
                     /locus_tag="ACN3HL_000910"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HHC8005804.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3502..5205
                     /locus_tag="ACN3HL_000911"
     CDS             3502..5205
                     /locus_tag="ACN3HL_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8005805.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5207..7240
                     /locus_tag="ACN3HL_000912"
     CDS             5207..7240
                     /locus_tag="ACN3HL_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HHC8005806.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7251..7691
                     /locus_tag="ACN3HL_000913"
     CDS             7251..7691
                     /locus_tag="ACN3HL_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8005807.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7891..9018)
                     /locus_tag="ACN3HL_000914"
     CDS             complement(7891..9018)
                     /locus_tag="ACN3HL_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005808.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9021..9698)
                     /locus_tag="ACN3HL_000915"
     CDS             complement(9021..9698)
                     /locus_tag="ACN3HL_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HHC8005809.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9962..11728
                     /locus_tag="ACN3HL_000916"
     CDS             9962..11728
                     /locus_tag="ACN3HL_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HHC8005810.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11743..12180
                     /locus_tag="ACN3HL_000917"
     CDS             11743..12180
                     /locus_tag="ACN3HL_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8005811.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12193..13344
                     /locus_tag="ACN3HL_000918"
     CDS             12193..13344
                     /locus_tag="ACN3HL_000918"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHC8005812.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13406..14104)
                     /locus_tag="ACN3HL_000919"
     CDS             complement(13406..14104)
                     /locus_tag="ACN3HL_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HHC8005813.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14097..15449)
                     /locus_tag="ACN3HL_000920"
     CDS             complement(14097..15449)
                     /locus_tag="ACN3HL_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HHC8005814.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15672..17072)
                     /locus_tag="ACN3HL_000921"
     CDS             complement(15672..17072)
                     /locus_tag="ACN3HL_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HHC8005815.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17233..17970
                     /locus_tag="ACN3HL_000922"
     CDS             17233..17970
                     /locus_tag="ACN3HL_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HHC8005816.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18095..18574
                     /locus_tag="ACN3HL_000923"
     CDS             18095..18574
                     /locus_tag="ACN3HL_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HHC8005817.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18571..19338
                     /locus_tag="ACN3HL_000924"
     CDS             18571..19338
                     /locus_tag="ACN3HL_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HHC8005818.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19568..20137
                     /gene="lepB"
                     /locus_tag="ACN3HL_000925"
     CDS             19568..20137
                     /gene="lepB"
                     /locus_tag="ACN3HL_000925"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHC8005819.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20241..20843)
                     /locus_tag="ACN3HL_000926"
     CDS             complement(20241..20843)
                     /locus_tag="ACN3HL_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HHC8005820.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20949..21179
                     /locus_tag="ACN3HL_000927"
     CDS             20949..21179
                     /locus_tag="ACN3HL_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005821.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            21170..21418
                     /locus_tag="ACN3HL_000928"
     CDS             21170..21418
                     /locus_tag="ACN3HL_000928"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005822.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            21524..22108
                     /locus_tag="ACN3HL_000929"
     CDS             21524..22108
                     /locus_tag="ACN3HL_000929"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HHC8005823.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22111..23184
                     /gene="prfA"
                     /locus_tag="ACN3HL_000930"
     CDS             22111..23184
                     /gene="prfA"
                     /locus_tag="ACN3HL_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HHC8005824.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23177..24016
                     /gene="prmC"
                     /locus_tag="ACN3HL_000931"
     CDS             23177..24016
                     /gene="prmC"
                     /locus_tag="ACN3HL_000931"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HHC8005825.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24009..24188
                     /locus_tag="ACN3HL_000932"
     CDS             24009..24188
                     /locus_tag="ACN3HL_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005826.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24210..25235
                     /locus_tag="ACN3HL_000933"
     CDS             24210..25235
                     /locus_tag="ACN3HL_000933"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HHC8005827.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25410..26654
                     /gene="glyA"
                     /locus_tag="ACN3HL_000934"
     CDS             25410..26654
                     /gene="glyA"
                     /locus_tag="ACN3HL_000934"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HHC8005828.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26807..27754
                     /locus_tag="ACN3HL_000935"
     CDS             26807..27754
                     /locus_tag="ACN3HL_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HHC8005829.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27888..28517
                     /gene="upp"
                     /locus_tag="ACN3HL_000936"
     CDS             27888..28517
                     /gene="upp"
                     /locus_tag="ACN3HL_000936"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HHC8005830.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28656..28898)
                     /locus_tag="ACN3HL_000937"
     CDS             complement(28656..28898)
                     /locus_tag="ACN3HL_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005831.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29019..29091
                     /locus_tag="ACN3HL_000938"
     tRNA            29019..29091
                     /locus_tag="ACN3HL_000938"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29052..29054,aa:Thr,seq:cgt)
     gene            complement(29210..29848)
                     /locus_tag="ACN3HL_000939"
     CDS             complement(29210..29848)
                     /locus_tag="ACN3HL_000939"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HHC8005832.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29971..30603)
                     /locus_tag="ACN3HL_000940"
     CDS             complement(29971..30603)
                     /locus_tag="ACN3HL_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HHC8005833.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30954..31253
                     /locus_tag="ACN3HL_000941"
     CDS             30954..31253
                     /locus_tag="ACN3HL_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HHC8005834.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31748..33913
                     /gene="acm"
                     /locus_tag="ACN3HL_000942"
     CDS             31748..33913
                     /gene="acm"
                     /locus_tag="ACN3HL_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HHC8005835.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34185..34670)
                     /locus_tag="ACN3HL_000943"
     CDS             complement(34185..34670)
                     /locus_tag="ACN3HL_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HHC8005836.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34760..35105
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35150..35791
                     /locus_tag="ACN3HL_000944"
     CDS             35150..35791
                     /locus_tag="ACN3HL_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHC8005837.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35810..36445
                     /locus_tag="ACN3HL_000945"
     CDS             35810..36445
                     /locus_tag="ACN3HL_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHC8005838.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36463..37278
                     /locus_tag="ACN3HL_000946"
     CDS             36463..37278
                     /locus_tag="ACN3HL_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8005839.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37597..39033
                     /locus_tag="ACN3HL_000947"
     CDS             37597..39033
                     /locus_tag="ACN3HL_000947"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8005840.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            39222..41669
                     /locus_tag="ACN3HL_000948"
     CDS             39222..41669
                     /locus_tag="ACN3HL_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HHC8005841.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41899..42966
                     /gene="rlmN"
                     /locus_tag="ACN3HL_000949"
     CDS             41899..42966
                     /gene="rlmN"
                     /locus_tag="ACN3HL_000949"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HHC8005842.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            42956..43162
                     /locus_tag="ACN3HL_000950"
     CDS             42956..43162
                     /locus_tag="ACN3HL_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005843.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(43159..44262)
                     /locus_tag="ACN3HL_000951"
     CDS             complement(43159..44262)
                     /locus_tag="ACN3HL_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HHC8005844.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44815..45363
                     /gene="aac(6')"
                     /locus_tag="ACN3HL_000952"
     CDS             44815..45363
                     /gene="aac(6')"
                     /locus_tag="ACN3HL_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HHC8005845.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(45611..45730)
                     /locus_tag="ACN3HL_000953"
     CDS             complement(45611..45730)
                     /locus_tag="ACN3HL_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HHC8005846.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
BASE COUNT        15671 a         7847 c         9339 g        12975 t
ORIGIN      
        1 atttttctta ctactcgaaa ctaagcgact ttttcacaac ctcttcctta aacggtgttc
       61 aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aataggagga gctatttttg
      121 tttggctgtt cttattactt gatgcagaac agctttttca caacctcttt ttataagagt
      181 ttttactcat taatttacaa aaaacaagca aaatgcgaat tttctcacat tttttttaac
      241 aaaatcaaag ttattgcttg aaagaagaag aatccatcgt taaaataaag cttgacgtag
      301 aggggagcaa gaaatatgaa agattttcaa ttgggggctg ccacctattt aaaaagtgta
      361 gccattcggg tgaaagaccg agataaaatg attgattttt acaagaacgt tgttggcttt
      421 gatttgaaaa gagaagaaaa cgaattagcc attttaggaa cagaagaagc tggaagtgaa
      481 atgttgctgc tggaagaaag tcctagagcg aatgatcaca tgggggtgat caaaaagctg
      541 aaccgttttt cattgattat ccctagcaca gaagaaatgg cagatatcct ttgtcgtatc
      601 cgtaaaatga attatccaat caaagaagct ttagaagatc atggacgtat ggggattttg
      661 ctcgtagacc cagaagagaa tgaattggaa atttaccatg aagagaataa gaacgaccaa
      721 agagaaattc cagaaacaat ggatcaagaa gcattattaa gaaaatctga agaaaaattc
      781 agtaaactat caacaggttc ttattttgaa aaaatccatt taaatgttac taacttaaca
      841 aaagaacgcc aatttcttaa tcatgtactt ggtttgaagg tacataatga agaagagggc
      901 atccatgtat tgaatgaagg agatttccat gttggtttga cagaagctag cggaggcgca
      961 attgatttgc ctacagatga agtgattgga cttgattttc tgaaattcat gatcgatact
     1021 gaaagcatgg aaggactgat tgctcacttg cagcaactat cagttgattt cttcttagac
     1081 aaaaagcaca cagtactcac aatctatgat gctataggaa tcgaatggtg gttcgtcagt
     1141 gagccaaaag aaaagaataa aactgacatt cgatgcgacg cttaactttt tctttcttaa
     1201 cgattgtcgc atgtctcgtc attttatgaa cggtcatact atcgcttatt ctagagatag
     1261 aaagagaaaa tagtataccg ggggaaactg cgcggttttt cgcgcagttt ttttgtgtaa
     1321 aaaaggttga ttcctcatag attaagcttt aagcttggac tgtaagaatc tgatagaaaa
     1381 gcaggagaaa aagatgtatc cacacacgaa acagcttatt ttgaaaaaga tggaagaagg
     1441 attttatcca ggtgtagcag tcgccttcat aaaagaaaat caagtagaaa catttacagc
     1501 cggctttgcc caagtcgttc ctgaaaagca gctgatgaca gaagatctgt tgtttgatgc
     1561 agcctcactg acgaaagtcg ttgcaaccac ttcattagtt ttacgtctat tagaagatgg
     1621 aaagatagaa ctcgatcaac cgcttcataa atatcttcct gaatttgaaa atcagacaat
     1681 cactttgcgt catttactga cacatacttc tgatatcaaa acatggatac caaacagaga
     1741 taagctatct caggaagaat tgatcgccgc ttatttgaag ctagaaccag gtgagcaact
     1801 aggaaaagaa gtaaaatata cagatgccgg tacgattctt cttgggttga tgctagagga
     1861 aatttaccaa gaaactgcag tggaaatctt tcaagaacaa gtattggaac cattaggaat
     1921 gatgaacagc ttatttcttc cttttccttc caaaaaaatc gttcccacag aacaactgcc
     1981 ttcgggtgag gttttgcgtg gacaaactca tgatccgaaa gcaagagttt tggctgaaca
     2041 tgcaggtaac gcgggtctct ttattgattt gaaagacagc attacttttg tccaaatgta
     2101 tttgaacaag ggaaaaatcc gtaatggtcg ttttttagaa gaagagacga ttgattcttt
     2161 actgcaagat caaacaccga aaaaaaatgg ctatcgttct ttaggatggg acttaaaaaa
     2221 ggatgtagaa gacggtcatg cgattctttt tcatactggt tatacaggta cgtttttctt
     2281 gattgatata aaaacacaag aagcgttgat atttttgtca aatcgcgtac atcctgtcga
     2341 tcatcgtgcg gagtatctca tatgtcgaga tgaaattgtt gaaaactttt tgaaagagaa
     2401 agcggtatta ccgaaataat gctataatag ctatgaaaaa tgagaggagt ttgaattatg
     2461 caggaaccta tgtttttaaa accagttttt caagaaaaaa tttggggagg aagtcgttta
     2521 cgttcagtct ttggttttga tatccctaac gataaaatcg gagaagattg ggcgatcagt
     2581 gcgcatcctc atggtgtcag tgtagtagaa aatggcgaat tcaaagggaa aagattagat
     2641 gaactatggt cagaacacaa ggaattgttt ggccatcctt cagaaccagt gtttccatta
     2701 ttgatcaaga tcttagacgc agaagatgat ctatctgtac aagtacatcc agatgatgcc
     2761 tatgggatga aacatgaagg tgaattagga aaaactgaat gctggtatat catcgatgct
     2821 gaacctggtg cagaaatcat ctatggtcat catgcaaaga caagagaaga actagctgag
     2881 atgatcaaag atgggcgctg ggatgacctt ttgaagaaag taccagttaa aaaaggtgat
     2941 ttcttttatg taccaagcgg aacgatccat gctattggta aaggaatcat gattttagaa
     3001 acacagcaaa gttctgacac gacttaccgc gtgtatgact acgacagaaa agatgcgcaa
     3061 ggacaaacaa gagagctgca tatccaacaa tcgatcgatg taacaactgt ccctgcgaaa
     3121 acaccagaat tacaaatcaa agaagtccga aaagggaatt catcgatcgt cacttattta
     3181 gaaactgagt ttttcaatgt atatgagtgg gatattaaag gaatcacatc tttcaaaaaa
     3241 caagcccctt atacattgat gacggtaatc gaaggagcag gagaccttgt cgttgacgga
     3301 aaaacatatc cattagaaaa aggaacaagc tgtattattc caaatggcgt ttctgagtgg
     3361 gcggtccaag gtgaactagc aatcattgcg tctgaaccag gcaaatagtt cccagatagc
     3421 tgaaagcagc agacggtttt tcgtttgctg ctttttctac ataaaatccg tccatcaata
     3481 aatagaagtc tggtgaaaaa gatggaatac aaatggaaag caaacaacag cagtcgcgtg
     3541 tctatgaaac aactgagaaa agctggacat cacttaaatg aaatgatcat gccaaatcta
     3601 agtctgttta tcgcttgggg aatcttgtca ttagcaacaa aaggtgtgtc tggcgatttg
     3661 cacaccacat tagaagaggt atgccattgg atgatccagc tgcttttacc catcttgatc
     3721 agttattcag gcgggaaatc ggtaggggga caaaaagggg cagtcgccgg tgcaattgct
     3781 tctttagggt tgatcgctcg ttccaatgct ccacaaatcg taggagcgat gattatcggg
     3841 ccgcttgccg gcatcgtata tgaacaattt gtttctagat tccatgtgaa attcaaggct
     3901 ggatatgaaa tgcttgtcag caacctacta gtaggactga ctggtagcgt tatttgtata
     3961 attggaatcg tttttattga accagtttta aatagtgttc acttgttgct cgcctccgtt
     4021 gtgtcttggc tagtcacaat gaatctgtta ccacttgtca gtctgatctt agaacctcta
     4081 aaagtactat ttttcaataa tgcaatcaat catggtgtat tgacaccttt aggaatcgaa
     4141 ttctcacaaa cagtcgggta ctcttcctta tttttgatgg aggcaaatcc tggacctggt
     4201 ttagggatct tactttctat cctttgtttt gcagaaaaac aggaaaaagt aaatgcgagt
     4261 ggagcattga tgatccatgc gattggcggg attcacgaaa tctattttcc atttgtcttg
     4321 ctgcgaccgt atctattttt agctgtaatg gctggtgggg caagcggcac gttgatattt
     4381 caatggttag atacgggatt agctgcacct gtatcgcctg ggtcactact cgtgattttt
     4441 gccaatgcgc cttatccaca actagctggg gtaagtatag ggatagcaat cagtacattt
     4501 gtgaccttca tttgtgcagc gatactattg aaattaccaa ataaagaaaa agagaacaaa
     4561 acggtcaaag aaaggggaga aatcttggaa ccatctatca ttcattccgt catttttgct
     4621 tgcgactcag gtatgggatc aagtgctatg ggagccgccc tgctgaaaaa gaaattagca
     4681 gcagaaaaaa tcgatctttc tgtcggatac agctctatct atgaattgaa taaccaagta
     4741 aatcagctgg ttatcgtgca acatgaacta gcgggtcttg caagagaaaa agtacctcaa
     4801 agtcaaatct atgtactgga tcactttttg gaaacagata tcttgctgtc acgaataaaa
     4861 gaagcgatcc aatttccaaa gcgggaagaa aaaaaagaga tagcagatat cacagaacaa
     4921 aaaacgtcgc ctgctaatat tgtatttttg tataaaaaca acagacgcgg ctcacaaact
     4981 atgggcatga cgattttaag tcaattagca aaaaaagcga aaaaacagtt tgttatctca
     5041 aaagaatcaa tagaaaaaat caaaatccaa gaagaaacga tttatatcgc acaaagagaa
     5101 ctagctgtaa ctgaacagct agaagaaaag atccctcggc tagttctagt tgaacattgg
     5161 gtagctacga atgaatacga aaaactcgtg aagggagaaa tataagatgt atttatcgcc
     5221 cagagaaaaa caattattag cagaatttct cagtagcccg tcacctgtat ctatccaaaa
     5281 aatgatgaat ttattgaagg tcagtaaacg gactatttac cgcgaattag ataatcttga
     5341 agtctcattg aaatcggtaa atgcttcttt gaaaaaagca gctagaggct catttgtcat
     5401 tgaggcatca gaagaagtat tagagcaatt aaaagaaaat acagatggga aaagtaatga
     5461 cttatccact gctaaacgac aacacgcgat tttagccgag ttgttactga cgacagagcc
     5521 gttgagtctt gctcatttca tggaatcata tcgcatcagt aataccactt tttatgcaga
     5581 tatcaaacag ttggaagaaa gtattcgcca actgcctttg gaaatcattc ggaaccaggg
     5641 atacgagatc gaaggaccgg aaaaataccg ccggcttctg acagcgaatg tattagaatt
     5701 agaaatcaat gaatatgaac tttttcatag tatttctttc gatgcatcac tgaattattt
     5761 ttttcgattc gttgatccgc aacatctatc tcttgcacgc aaagtaatcg gggaagaatt
     5821 gatccaaaaa aagaccaatc taagtgatag aaagcttgaa catttggttt tgatgctgac
     5881 attgacgatg gagcgtgtga cgaaaaatca tttactgaca aatgagacat ataatagtct
     5941 ggcaaacaaa gaattactac agacagctaa acgattgttt tcacggatcg cttctgagac
     6001 aaaacaactt tatccagtaa atgagatcgt cttttttgca ggattattaa atgacttcac
     6061 gaactcattt gatcagaatt tctttgaaga gacgttcgat acacagcttg cttatttagt
     6121 aaaacaactg attcaagaag taagtgaaga gacgaatgtc catttttatg aagatgaaac
     6181 tttgtacaaa atgctgttga ctcatttatc tggtgtgttt tcaagagccg ttttacaaga
     6241 agagacactg accaatccga ttttagaaaa aatcatggtt caatacgagg aagttgcgaa
     6301 tgcaatccgt aaagcagtag agcggatttt tcaagaaaaa aaattatccg aagaagagat
     6361 cgcttatatg gtccttcatt ttgcgaattc attggaacga agtccgaaag aaagcaatat
     6421 cagtattgca ggattttcgc caagtggatt agcttctact agcatgttgg aactacgatt
     6481 gaaaaggtat tttcccttca tccaacaaat tcatttctat cggattgctg atttaaaaaa
     6541 aatcgattta caagaagaat atgatgttgt tatttctaca tctattttac caggatacgg
     6601 tggaaaatat attttagtct ccccgctact gctagaagat gaagtcaagc agctaaaaga
     6661 agctttttcg catattgaga agaaaaaaag gcaaaaaatt acgtataaca gcaataacga
     6721 gtggatgata gaagatactt atgaggaaac aatgcatttc atggatcaaa tcaatcaatt
     6781 actcggtcgt ttttttatcc aagaactgga taatcctgag acgatttccg aaacgattcg
     6841 cagcttattt ccttattttc ctgaaggact agtaacggat gaagaggtgg ttcatcgccg
     6901 gctgcttaag cgatatgaac aagcacctat cggtattcct catacaaata tggggttatt
     6961 ccatacatcc agctcattga tttctaaacc gatcttttgt attttcaatt tgaaacatcc
     7021 gttgaccatt gaagggatgg atagacagcc agtcgatttg tcccgtatgt tagttatgct
     7081 ggcgccttcg ccaatccaag aaaaagacgg gattctttta ggaaagatca gtggagcaat
     7141 catcatgaat gacttgaaca ccgagatctt ccgctcagga aataaagaaa tcgtttatca
     7201 gttgttagcg aaaatcctga ttgaagaaat aaagaaatga aggtgaaaag atgatacagc
     7261 taccagcaga aaaaatattg ctcgatcaat cctatcaaaa ttggaaagaa gcgttgaccg
     7321 agatcggcca gtggatgacc caacaagggg gaatcaaacc ggcatatatc caatcaatga
     7381 tcgaaagaca agaaaaagcg agtgtctata tcgggaattt cgtagccttg ccacatggga
     7441 ctgacaaaga tgaagaagta gtagaagaag gaatctattt agtccaagtg cctgatggtg
     7501 tggactttgg aacaaaagag gaaccaaaaa tcgcgacact cttatttgta gtggctttaa
     7561 aaaaagaaca tcagttagcg gtgctccaag atttagcctt tttctgttca gacatcgacc
     7621 aagtaatggc gctcagtgat gcggaaacca ttgaagaagt ccaaatgatt tttgaacatg
     7681 gacatatata accaatgttc acagtaaaaa aagctgcctt gcatcaagta ataacttcaa
     7741 ccaagataaa aataagagga gctatttttg ttgggaggtt cttattactg cggatgcaag
     7801 cttttgaaaa ctatttattc tagaaaaccg tttatttgaa ataggggacg gtgacaaggt
     7861 ttttgtcacc gcccctatta tttttgtgtt ttaatagctc ttttttatat agatagtgcc
     7921 catacctatg aataataaaa cgatactcca tataccaagt gtcaagatac cattcatgaa
     7981 agtaacctgt tctgaagcta gtggcgagaa aatatctcct cctatgatca cattttgaaa
     8041 atcaacataa gaagttggca agtaatgact gattgattct atccatccaa tcgaagaaaa
     8101 caagcgatac tctgctaaga aaagacaaag aagtgtacct aaaagattga ctagagaatg
     8161 ttcaaataaa gcagatagaa gaaaactgat tgtacttaaa aagagcaccc acaacaacag
     8221 gaacagaaag ctctggaaaa gatactcata catcggcagg attcgtatct cctgaccaat
     8281 gatcgttcct acaggataac ggaagtctcc caaaccattt ttgattatta ctagtataga
     8341 gacgatcaaa aatggcatca cgagacttag catagctgca ccataataaa tggtaaaacg
     8401 gatgctatgt ttctttacca tactatccgg taatagattg actagagaga ttacctgctt
     8461 tcttttttca taagagatga tggaagaaag aaacaaggcg gttatacata aaatcaaaaa
     8521 actagaaatc attcctgaaa aaatattttc gtagtaattt gctaaagaga gatgcgctgg
     8581 caagtcaaaa atagaatatc tttggatctg atgttctttc atataacgga gcaactcgac
     8641 acgtttttgt tgttcaatga ttggaattcc ttgtctttga ccagaaatca gtcgatccag
     8701 tatatctttt tcataatgat aagttgcttc gaccatttgc tggacattcc ctgtgttttt
     8761 tgcatgtaag attgcttcga tcagtttgtt gcttttctct aaactttcca caaattcttt
     8821 ctcattctca tcttctttca acgtttcaat caaacgttgc atctcttcat agttatgatt
     8881 cagttcatcg aattctgtat aagcaagttt atgatcaaaa aaaagtggga atgcaaagag
     8941 cacgaccaac aatagaggaa ataaaaagtt tactttgttt tttagtaaga gattgcgttc
     9001 aaatgtaagt aaagacatag ttacacctca tataatttac gataaatagc taaaatctct
     9061 tccatatttg aggattctgt gacgatttct ccatttttta gaaaacatgc tttagaacaa
     9121 atcgattgga tattcgcgat agcgtgggaa gaaagaagaa tcgtcttccc ctctttctgc
     9181 cattgtctga tgaggctatt caagatatca atacttcctg ggtctaatcc gttcaacggt
     9241 tcatcgaata acatgacaga tgaatcactg atcaagtaag cagcaagcaa gacatgttgt
     9301 ttcattccta gagacatttt tccaatcggc aaagtaaggt actcagtcat cttcaatcgt
     9361 tggaaaacag tttggcattc tactttgctc tgccaatagt atttgatcaa agtcaaataa
     9421 tcaacagccg atagatagtc ggataactga ttcgttgatt ctagaaaaaa gaaagaccgg
     9481 cgataatctg tataagcagt aggagagatg ttgtgaaggg acaattgatc ataagttgtt
     9541 ggcagcagtt gggcaatgcc attcagcaaa gttgttttgc caaatccgtt cggggcaatc
     9601 aaagcagcta cttctcctga ttctactaaa agattcaatt gtcgaatcac acgtttttta
     9661 ccacgtttca tgttcatgtt tttgatcagt aatgtcatag ataggcctcc aatataaaat
     9721 ttaataacat aatagaatgg aaaacatcta aattaaatgc taacaaaagt tattgtttgc
     9781 atattataaa aaaattaaaa taacagtttt atttaaaatt gaagttttct gataccgaaa
     9841 tctttttatt ttgctgacat actcaaacct ttggcacaaa gtttcgtgcc aaagtacgac
     9901 tatttctctt tttagtaagc ggatacaatt agagtatcaa aaggagagag ggagagacaa
     9961 aatggaacgg acgattccca aaaacaacat ttcgctaaaa gcgagggtac aaaaattagg
    10021 cagtacttta tcaagcatgg tcatgccaaa tattggagca ctgattgcct ggggtgtatt
    10081 aacggctcta tttatcccag atggttattt accaaatgag gctttcgcta ccatggtaag
    10141 cccaatgcta acttatctga ttcctttatt gatcggttat actggcggaa aagtaattgc
    10201 tggtgaccgc ggatcagttg ttggggcaat tgcaacgatg ggtgtgattg tcggaacaga
    10261 tattccaatg atgctaggcg cgatgatcat gggacctctt ggtggatatg ccatcaagaa
    10321 atttgatcag ctattccaaa aacggatcaa atccggtttt gaaatgctag tcaataattt
    10381 ttcagcaggt cttatcggtt ttggattagc gttattaggt ttttctgcga ttggtccagt
    10441 tgtcgatgca ttgactcaag caatggcaaa aggtgtagag atcattttat ctgcccattt
    10501 gattccattg acaagtattt ttattgaacc agcaaaaatc ttatttttga ataatgcaat
    10561 caatcatggg attttgacac cattgggaac tgaacaagta gcagaggctg gaaaatctat
    10621 tctattcttg cttgaagcaa atcctggtcc aggacttggc gtattacttg cttttacttt
    10681 gtttggcaaa ggagcagcaa aatcttcagc accaggagcc atgatcattc actttttagg
    10741 cgggatccat gaaatctatt ttccttacgt tatgatgaaa ccgttattat tcttatcagt
    10801 tataggcgga ggaatgtcag gaagtttcat tttccaattg atggatgctg gactaagagc
    10861 gccagcttct ccagggtcga tcattgcgat tctagcgatg acaccgttca attcttacct
    10921 tcctgttatt ttgggcgtga ttgttgccgc agctgtttcg tttggtattt ctgcagtaat
    10981 tttgaaagcg gatgcgaaag atacaaatga agacttcgaa aaatctgttc aagagacaaa
    11041 ggcagctaag caagcttcca aaggtgccca aggtattcct caaggagcta cattctctgg
    11101 cgtacaaaaa atcatttttg cttgtgatgc aggaatggga tcaagtgcga tgggcgcttc
    11161 gatcttgaga aaaaaagtac aggaagcaga cttgcctcaa acggtgacca atcaagcaat
    11221 cagccaactg acagatgact cgaatacatt gatcgttact caggtcgaac tacaagaaag
    11281 agcaaaacaa aaagcaccga gcgcgcgttt tgtctcagta gaaaactttt tgaattcacc
    11341 tcgatatgat gaaatcattc aagaattaag cagcaagcag aaaacatcag tttctgaaat
    11401 tgagaatgag ccagcagaag agtttctttc agcaaacatc aaacaaatca aagagattct
    11461 acttgtccac gatgatcgtt ccggatcagc aacaatgggg atgaccgtgc tcaaagatat
    11521 attagacaag aaccatttaa ctatcccgtt aagaaaagtc aatatccaag atttaaaaga
    11581 tgaacctgat tcactgatcg tagccaaaga aagtttagcg gaaaaagtac agatggctgc
    11641 acctcaatcc attcatttat cagtcaacag catggtcaat ccgcaaaaat acgaatcgat
    11701 tgcacaatat ttgaaacaga cagcttaagg gaggaaaaca gcatgcaaag tttgccattc
    11761 gacatgatcg agctcaatcg atcttttaaa accaaagaag aagcgatccg ctattgcggt
    11821 cagatgcttg tagaagcagg gtgcgttgat gaggaatata tcgatgccat ggtagataga
    11881 gacaaaatgt tatctgttta tatggggaat tttatcgcga ttcctcatgg aacagatgaa
    11941 gcaaaaaaat atgtgaaaaa atccggcatc tgtgtcgttc aagtaccaga tggtgtagat
    12001 tttggtaccg aagaagaaga aaagattgcg actgttttgt tcggtattgc aggagtcgga
    12061 gatgagcatt tgcaacttgt acagcaaatc gcactttatt gcagtgatat ggacaatgtt
    12121 gtccagctag cagacgcgct cagcaaagaa gaagtaacgg aaaatctagc aattgcttaa
    12181 ggagagagaa aaatgagagc agtacatttt ggtgcaggaa atatcggtcg aggatttatt
    12241 ggagaggttt tggcagctaa tggatttgag attactttcg tagatgtgaa tcacacgatc
    12301 attgatgctt taaatgaaag aaaagaatac gaaatcgaat tagcagatga atcaaaagaa
    12361 aaaatcactg taaaaaatgt caaaggaatc aacaatcaaa caaatccaga aaaagtaatc
    12421 caagaaatcg ctgaagcaga tttagttact accgccattg gcccgaatat cttacctttt
    12481 attgctgagt tgattgcaaa aggtatccaa gaaagagaaa aggaaggaag cacaacatct
    12541 ttagatatca ttgcctgtga aaatatgatt ggcggttcag catttctaga aaaagaagtg
    12601 tataaatatc ttccggaaac atcatttact gacaaatata tcggctttcc aaatgcagca
    12661 gtcgatcgaa tcgtcccatt acaacaccat gaagatcctt tattcgtcca agtggaacct
    12721 ttcaaagaat gggtcattga cgatagccaa agaaaaaata aaaaaatcca attaaaaggg
    12781 gttttatatg tagatgatct agaaccatat atcgaacgca aactatttag tgtcaatact
    12841 ggtcatgcga ctgtcgctta tacaggtgcc ttgttaggtt accagaccat tgatgaagca
    12901 atgcaagatg cgttagttgt ggcacaatta aaatcagttt tgcaggaaac aggaagtttg
    12961 ctgattgcca aatgggggtt tgatgcagag cagcatcatg cgtatattga aaaaatcatt
    13021 catcgcttcc aaaacaaaaa tatctctgat gcgatcacac gtgtcgctcg gacaccatta
    13081 cgtaagttag gttatcaaga aagatttaca cgtccagtga gagaactaca agaacataac
    13141 ttgacttgcc cacatttgac ggcaacaatg gggattattt ttaattacta tgatcctgaa
    13201 gatgaacaaa gccgtcaatt gcatgaaatg aagatccatg aaaacttgga acaattgatt
    13261 caagaagtca caggaatcaa tgatccgaaa acaatcggga atatcaagca aaacgtgaac
    13321 cgttatgcca agcaagtcgc ttaaaatagg atacgaaaaa ggggaatgtg acgaaatttt
    13381 tgtcacattc ccctttttcg aataactagg ctgtttgtcc ttcaagatag ggcagatcca
    13441 attctttacc gtaacgttgt tctaaagcta ggcggatcaa acgagctgcc aggttctcat
    13501 ttcttgcaag gataggtcca tggaaataag aaccgaagac atttcggtaa atgacacctt
    13561 cagattggtc ttcaccatta tttccttgac cttgtaccac tttccccaaa ggtcgttcac
    13621 cttcacctaa gaaagtccga ccattgtggt tttcaaatcc ataataagtt tcattgaatt
    13681 cttcgttatg gataacgata tcaccgataa accggttatt ttcctgactt aacgtgtagt
    13741 gatccagtgc actgattcct tggatctttt ctccattagc tcccatgtag tagtgaccta
    13801 gcaattggta gccaccacaa atggctaaca tgacgccatc attttcgata tagttgatca
    13861 aagaatcttt ctttttctgg atgtcttttg aaatgattaa ttgctcaaag tcttgaccac
    13921 cgccaaagaa aaccaagtca tatttatcag catcaaaagg ttcatgtata ctaacgatct
    13981 ccgtatggca agaaaccccc attttttctg ctatatattt caacatcaaa aggtttccgt
    14041 tatcaccata tgtgttcatc aaatttccat aaaggtgggc gatattgagt tcataattag
    14101 ccacggttca ttcctccttt gataaatcct tgagcagcta gttctttacg aagctgcaat
    14161 acagcagtgt aagtagctaa aatatagaca tgctcagttg gcaattcttt gattttttcg
    14221 attacttctg gtaattcttt tgtttctgtc aatttatttt ctggaatccc ggcaactttt
    14281 agacgtaaag tcatatctgt atgacggtct cctccagaaa taacagctgg gatatccata
    14341 tcggcaaagt tttcaaaatt accatcccaa atccagctga catcgattcc gtctgcgtaa
    14401 ttggcattta ataaagccac taaagaaaat ggataaggag ctagaccaat catatcgatt
    14461 acttgattga tacctacagg atttttgaca agtactaatg tacatttttt cccattgata
    14521 ttgatgactt cttgtcggcc gaatactttc tcgtcatatc ctaaaccttg tttgatttta
    14581 tcaggatcga cattgaagta ctctgccact gcagtagctg ctaaagcatt gtagacatta
    14641 tacataccgc caacttcgat tccgtattca tgaccatcga tcacgaaatc tgctgacaca
    14701 ttgtccatcc gtaccatatc agttaatcga taatccaatt caggacgttt gaagtcacaa
    14761 tttggacagt aatatttccc taagtttgca taagtgatca ttttataatg caagatgtga
    14821 tgacaatttg gacataagac accgtctgta ttgtaatgag ccatttgttc acgatcttct
    14881 tcatggtcaa agccataata ttttctagga ttgactgttt cgatagaatt gaagattggt
    14941 gaatcaccgt tactgataat cgttgcattt ggtgactttg cggcaccgtc tacaatcatt
    15001 ttataggtcg tatagatttc tccataccga tccatttgat cacggaaaat atttgtaaat
    15061 aagaacagtt ctggtttcat atattctgtg actttgctca aacttgcttc atctatttct
    15121 aggacagcaa actttttctg tccttttttt ggttttgcct gcaagaaagt cgatacaatt
    15181 ccctgtacca tattcgcacc agtagggttg gttagaactt catcgaattg ctggcgcaaa
    15241 atattgactg ttaaagcggt agtcaatgtt ttaccgtttg ttccggtgac aacgacgact
    15301 tggtagtctt ttgccaaact atctagtata tgtggatcga ctttcagcgc tagtttacct
    15361 ggtaaacttg atccgccttt aaaaaaagtt tttaatgccc attgcgacgt ttttccaact
    15421 gcaatcgcaa aatgactgcg tattcccatt atgtaacctc caaaaacgat ttgctgacga
    15481 ataaattcaa ctaatcatac catatgttga aaaaaaggtt aaattgcttt tcttattctt
    15541 aagaaaaggt tacggctgaa agtgcatgaa atcggacaaa atcgcatgat ttaacaaaaa
    15601 aacagcttga aacaaaatga ttgtttcaag ctgctgtgat tttattattc cctcttacct
    15661 atattcccat tttaaccgat aataattttc tcgcttggat attcatagcc tagatctcgt
    15721 gtttcttttg gcacgaataa catcaatgta tatagcattc cgatccgccc aataaacatc
    15781 agtgtagcaa tcgtgatttt gcccacaaca gacaagtctc cggtaatccc taaagataaa
    15841 ccagttgttc caaacgcaga agttacttcg atgatgatcg agatcagcgt ttgttcttct
    15901 gtagcagata aaaaaacgat acaaaagaaa cacataccaa gagaaagcat aaagacaacg
    15961 actgattttc gcacatcatc ttgatcgatt ctccgtccaa aaatattgat gttatcttca
    16021 cttttgagga aggaatatag atacaaaccg atgattgcta cagtagttgt tcgaatcccg
    16081 ccgcctacag aactaggact gcatccgata aacatcagta aagaaaaaat gatcagtgtt
    16141 gtgatttgaa aatcacccaa atcgtgaatc tgcagaccag cattacgagt cgtaatcgaa
    16201 taaaacatcg aattgatcca tttgacactc atattggaat cttggaataa atggtccttt
    16261 tccaatagat aaatcaagac agttcccgaa acaaacaaga taacaaaagc taacacagct
    16321 aatttggtaa acaaggaaaa acgaaacgga agcttcgcat tggaacgttt gtataatagc
    16381 cattcccggc actccatcaa tacaggaaaa ccaattcctc cgacaaaaat caaaaacatg
    16441 atcaggatca agaaaaaata gtcatgtgca aagggcttga tggaatcccc agtgacgtca
    16501 aacccagagt tcgtgacagc cgatatcgcc tgataaaaac cgtaaaaaac ggcatcacgc
    16561 caacgatcaa aatagcctct gtaataaaaa taaatagaaa agaatgtccc aaaaagtaat
    16621 tgaaaccaga ttaaaatagc aaaagtgatc cgaatcagtc ggacgatacc agacaaacgc
    16681 ggttgattca tatccgtcat gatcagctgt cgctgtttca gtgtgatccg tcgtttagaa
    16741 aaaatgacaa aagcagtaga aatcatcatg atccccaaac caccaacttg aaataatatt
    16801 tccagcagta taataccgtt atcattgaac acagaattga tatcaaaagt cgatagtcca
    16861 gtcacactca ctgtactgat tgccatgaac agcatgtcca caaaagaaac atggctatct
    16921 ggttcgcgaa aaatcggcat ataaaataga acgagtgata agaccgtcat caatatataa
    16981 taaaaaacga tgatttggat cgatgagaaa tgattggcag caaacttctg tcctcgccgc
    17041 tgcagccttc gaaagaataa atcaacatgc acagtactat cctcctgaca atagtcgttt
    17101 ctaccagtat acaaggggaa ttaggaatac tcaaagaaat tatcaaacag ataacaatac
    17161 agctttcgat taaaatagaa atggcttata ataaggaaaa tcctagaaaa aagaaggagg
    17221 aggaataaca aattgattaa tgctcaacaa atcgtagaaa aaatgaaaaa tcaaaaaata
    17281 aattatgata cagttctgaa aaaaatgatc atgcaatggg agaaagaaga agtaaagcct
    17341 aagatattaa tacatacatg ctgtgctcct tgcagtacgc acacattgga attcatgtct
    17401 caatatgcag agatcacgtt atttttttca aattcgaata ttcatcctaa aagtgagtat
    17461 ttgcgaagat tacatgaaca aaaacgattt gtagaccaat ttaatgagaa aactgaccat
    17521 catgttgcgc taatcgttga tgaataccgt ccaaatgaat tcaccaaaat ggttttaaca
    17581 aaccatcttg aaaacgaaaa agaaggtggt gctcgctgca gtgcatgctt caatatgcga
    17641 ttagatcttg ttgcgcaaaa agcgcaagaa ctaggatacg attactttgg aagtgccctg
    17701 accatctcgc caaagaaaaa tgcagctttg atcaatcaga tcggaatgga tatccaaaag
    17761 atttacggga cacaatactt gccaagtgat ttcaagaaaa acaaaggcta tgaacgctct
    17821 ttgcaaatgt gcaaagagta tgatatttat cgccaatgtt attgtggttg cgtgttcgct
    17881 gccaagcagc aaggatgcga tctgaaagaa atcaatcggg aagcaaaagc ttacttaaaa
    17941 acatcaaccg tagtttttga ggaaaattaa agaaatcttt cggaaaaacg taagaaaaaa
    18001 ataaagaatt tatggtagaa ataaggtaga ctgtataatt tgtccgtagt aaagtaagga
    18061 aacaagaata aatttcaatg aaggaagaga taagatgcga aaagtagcac ctattttgaa
    18121 gccaatcgct gtattaacaa tctcgacgat tgtcgcgact actacaggta ttgtgaatag
    18181 ttccagctac cgtgcaccaa gttcaagttc tagtactgta gaagaaacaa caccaactac
    18241 ttcagtctcg acatctgaac caacaacaac ggaaagtttg aatgaaacca ctacgacaag
    18301 tacatgggac gatacaacaa ctagttcgtc gtatgatgag acatatacaa ctgacagctc
    18361 aagcgaaaca agtaatacgg taccagatgg cactccatcg gattcaacca atccaagtac
    18421 aagtccggat acaagtgcta gctccgaaac gataccaagc agtacgactg tagatgataa
    18481 cacgcaaaat gatgatgcag cacgtacagc acagcaaaac caagattcag gaaataccca
    18541 aacgtataac cagcaagcag gtgattctca atgacatttt tactagacct tatcaacggg
    18601 gtgcataaat tccttggcta tttagacatc agtcctaaat atcttaaccg tggatatacg
    18661 attttaagtg tgattcccac gctttattta ttgagaattg tttatggact ttggcaaaac
    18721 caaaactatc ttcaattttt cttatatgga cttgcatttc tagtgcttgt ttattttact
    18781 gttttaaatg tattttatta ctttttagat aaaaacacga aagccgatgt cactcagctt
    18841 tttgtgaagt atttacctga tgaagcgttc aacatccaga cagaagaatc gatagataat
    18901 ggaaattcga tcgataaagt gaatacacaa gaggtcatgg tttcttatga cgaagattat
    18961 caattgaaat tagccgagaa tatgcggtat ttgattggaa atggtgagat caaaacaaat
    19021 gaactcggtc gcatggatgg atttctggtc gatagaaata cattgtatcc ttattactat
    19081 gtcaagaaaa caggagagaa agagtatgtt ctaaatattg gacgaagcta ctcggacatg
    19141 gaaaaagtag ggaccattcg acttgactca acagaagaca cattggaacc tgtcggattg
    19201 ttcatcgtcg gcggtgattt tgtcaaagac gggttacgct atcatgagcc ttatcgtctg
    19261 aaattgattg caaaaaaggc acagtcgcag gaagaaccag tggtttatag tcgtagccaa
    19321 agaagaagac attcataatg tgatgaaacg ccgtgtatca gtggttgcga taaaaacgtt
    19381 tattcggaat aagggggatg tgacacgtct tttgtcacgt tcctttttta tataacgaga
    19441 aagataagac gaacacatca cttattcttt cctttcattt ataaacattg tagaataaag
    19501 aaagtacaac gaagtattgt gaaaaaacgt aataaataac gaggaaaata caagtaggag
    19561 gtaagctgtg aaagaatttt tgaaaaattg ggggattttg atccttgtat tagcggctat
    19621 tttattagct agagtgtacg tgtttacacc agttactgta aacgggcatt cgatggaccc
    19681 tacattaagt gatggacaac gattgatttc atctaagatc tcaaactatg aacgaatgga
    19741 tattattact acaaaggaac cgggggatga agaacggatg attgttaaac ggatcatcgg
    19801 tatgcctgga gatacagtca agatggaaaa tgaccagttg accattaatg gcaaaaagta
    19861 tgatgaacct tatctggatg agttcaaaaa agaattttca gaagataagt tacaaggaga
    19921 atatgcttat agctcaggat tccaagcaca agcagaaagt tcatccacct ttacgagtga
    19981 ctttgaatat actgtgccaa aaggaaagta tcttgttcta ggcgataacc gcttgatttc
    20041 aaaagacagc cgaatgtttg ggttagtcga caaagatatg atccaaggaa aagttgtttt
    20101 ccgttattgg cctctttcag aaattaaaat catgtgatga aaaaataaaa agaagctgtg
    20161 acatgttttt tgtcacagct tctttttccg aaaattcctt cttatttctt ggagttgctc
    20221 actttttttg caatctcatt ttaagctttt tggctgatgg ataagaaaag cgaagcgttt
    20281 ttgttcataa atagcttttc cccacgatgg aaggtatgac tagtagcaga gacaaagccc
    20341 gttttttcca atcgattatt caattcttct tggctaaagc cattatggac tttcggatga
    20401 ctaatttgtt cattcttgtc aaagtctacg atgatcaatt gaccgccagg agctaaaatt
    20461 tcataaagtt ttgtaagaat attctccgta tcaggaatgt gtaaaagtac aagtgataga
    20521 aggatgagat tagcttggac agcaggaaat tcgacagaag catcagcgtg gatcgttcgg
    20581 acatttttca gatctgctgc ttggatcttt tcttctgcca ttttcagcat agtttctgaa
    20641 gcatcggcaa tgatcagttc tttgaatctt tccgcaagcg gtaaactaac aagcccagtt
    20701 ccgcctccgt aatccagcag gactttttgg tggctgtcgc gcggtagata agtagttagt
    20761 tcttcgcgaa taatcttggc taatgcttga cggtcagggg aatcataatg gttagcgatg
    20821 gaatcaaaaa tattttttgt catcaaatag ctccttacgt aaaactttga aattttaact
    20881 tattatagca cgtgaaaaga aagaaagcat gctatactca attcaaaaag ggagaatcta
    20941 gaaagaatat gccgatatcg tttgtaaaag atagagagga aaaaggaaag tgtgtccgag
    21001 aaatattact agacttgcct gagtggtttg ggcttcctga atcaacggaa aaatatatcg
    21061 aggaatcaag taaactacct ttatggtgtg aaaaaagaaa agaagaatat ttaggcttta
    21121 tcactctttc acagacaagt gaagatactg ccgaaatcta ttctattgta tgggaataaa
    21181 aaaagactat catcaccaag gattaggaac aaaacttttt aaagaagcag aaggttacgc
    21241 agcaaaacat tacaaatatt tgcaagtgaa gactgtagac gaggggcact actctatata
    21301 tgatcaaact atttgtttct acgaatcatt aggattttca aggttggaag tttttccaaa
    21361 tttatgggat gaatggaacc catgtttagt tcttgtcaaa aaattggaac aaaagtgagc
    21421 aatagattta atactaatct gtgcttgatg aaaattctca ctgtaaaaaa tgctgaaaat
    21481 caagtataat accataggaa caaactggaa ggtgaaaaag agcatggcac aactattttt
    21541 taagtatggc gcaatgaata gcggcaagac gatcgagatc ctaaaagtcg cacataatta
    21601 tgaagaacaa aataagccag ttgtcttaat gacaagcggt attgatacaa gagatggttt
    21661 aggcgttgtt tcaagccgaa tcggactgaa acgtaatgcg atgccgatat ttgaagaaac
    21721 agacgtattt gacgtaattc agaaaatgga aagcaaaccc tattgtgtgc tgatcgatga
    21781 agcgcaattc ttaaaaaaga aacatgtcat tgcttttacg agaattgtgg acgaattgga
    21841 tattccggtt atggcatttg gtttgaaaaa tgattttcga aacgagttat ttgaaggatc
    21901 aaaatattta ttgctttatg cagacaaaat cgaagaaatg aaaacaatct gttggttctg
    21961 ccacaaaaaa gcaatcatga atttacatta tattgatgga aaccctgttt atgaaggcga
    22021 tcaagtgcaa attggcggaa atgaagctta ttaccccgtt tgtcgaaaac attactttca
    22081 cccatcaatg attacagaag gagaataagc atgtacgatc aattacaagc aattgaagac
    22141 cgttatgaag agcttggaga acttttaagt gacccagaag tgatttctga tacaaagcgt
    22201 tttatgcagc tttcaaaaga agaagcaaac acgcgcgaaa cagtcgaagt ttatcgtcgt
    22261 tataaagaag tagtacaagg aatcaccgat acagaagaac tgcttggtga aaaactggat
    22321 gatgaaatgg ctgaactagc aaaagaagaa ttatctgaat taaaaaaaga aaaagaagtc
    22381 ttagaagaaa aaatcaagat cttgctttta ccaaaagatc caaatgacga taaaaatatc
    22441 atcatggaaa tccgtggagc agcaggcgga gacgaagcag cattattcgc tggcgatctt
    22501 ttcaatatgt accaaaagta tgctgaagca caaggctgga aaacagaagt gatggaagct
    22561 aacgttaccg gaatcggtgg atataaagaa gtgatcatga tgatcaccgg agacaacgta
    22621 tattcgaaat taaaatatga aagtggtgcg caccgcgtcc agcgtgttcc ttcaactgaa
    22681 tcgcaagggc gtatccatac ttccaccgca acagttgtcg tgatgccaga agctgaagaa
    22741 gtagagatcg atattgaaga caaagatatc cgtacagata tctatcatgc ttcaggtgct
    22801 ggcggacagc acgtcaataa aacagcatct gctgtacgtt tgactcactt accaacaggg
    22861 atcgttgttg ctatgcaaga tgaacgttct caaatcaaga accgtgaaaa agcaatgaaa
    22921 atcttgcgtg ctcgtgtgta cgataagatc cagcaagaag cacaaagcga gtatgatgcc
    22981 aatcgaaaat cagcagtcgg aactggggat cgttcagaac ggatccggac gtataatttc
    23041 ccgcaaaatc gtgtgactga tcatcgtatc ggattaacta tccaaaaatt agatcagatt
    23101 ttagcaggga aattagatga gatcgttgat gcattgatca tgtatgatca aacatcaaaa
    23161 ctggaagcta tgcaaaatgg gtaaaatgac ctatcgagaa gtcctgtcac gggcttcttc
    23221 ttttttagag gatcatggga aagaagcata tagtatccaa tttttatttt tggaacgaaa
    23281 acaatggaaa aaacttgatt ggctccttca tatgaacgaa gagatttcag aagaagaaca
    23341 gcggttgatc gaaaccgatc tgcgacttct gcttgcagat catccacctc agtatttgct
    23401 aggatatgca gatttttatg atcatcggtt aaaggtaact gaagcaacac tgatccctcg
    23461 accagaaaca gaggagttag tcgaatggtg tttagacgag acgcctggtg taccgttaga
    23521 agtgatagat attgggacag ggactggagc aattgctatt agtttgaaag cagcaagaaa
    23581 aaattggcat atatctgctg tggatctttc agaagaagca ttagaagtag cgaaagaaaa
    23641 tgctcagaaa gaaggaacga aaatcagttt ttatcatgga gatacattag gaccagtaat
    23701 ggatcagcaa tttgatgtga ttatttctaa tccgccgtac atcagtcgga atgaatggga
    23761 actgatggat gaaagtgtcc ggtcattcga acctaaaatg gccctttttg ctgagaacga
    23821 tggattagct atttatgaaa aaatagcagt tgaagcacca agcgtactaa aatcaaatgg
    23881 aaagattttt ttagaaatcg gatttcgcca aggtgaagca gtaaaaaaaa tatttcagca
    23941 agcatttcca gataaaaaag tggcgataaa aaaggatctt tttggcaatg aacgaatgat
    24001 ccaagtttat ggttgaagtt gtggatgaaa aattttttat ttgttttttt attataaaaa
    24061 aacacttatt tgacaaggat gtaaacgact ttttggttta tcaacaagtt tatccactat
    24121 tgacaaatag attatccaca aacagtggaa aacttgagga taaactcaga caaaataaga
    24181 atgtatgaaa aaggggttgt ggataaactg tggaaacgaa acgatatgat gaaacagaat
    24241 tgcaagaggc agccgaagca ctgaaagaag gagaacttgt tgcttttcct accgaaacag
    24301 tatacggatt gggcgccaac gctcttttac caaacgctgt caagaaagtg ttttctgtaa
    24361 aagggagacc gcaagataat ccattaatcg tccatgtcgc ctcttttgaa caagtaaaag
    24421 agtatgtgga caactttcat ccggcagcag agaagattgt gaagaacttc tggcctggac
    24481 cattaacttt gatatttaag atcaaaaaag acactttgcc ctcagttgtg acgggaggat
    24541 tatccacagc tgcatttcgt ataccggata acaaaaaaac actagaagta atcgaacttt
    24601 ccggtgttcc gcttgtcggt ccaagtgcaa atacgtcggg aaaaccaagt ccaacgactg
    24661 cagatcatgt atatcatgat ctacaaggaa aaattaccgg gattattgat gatggagcta
    24721 cgcgaattgg tgtagaatcc actgttcttg atttaagtga tccaacagcc atgcctatga
    24781 ttttacgacc aggtgcagta acgaaagaac aaatcgaagc agtcatcgaa tctcctgttg
    24841 ctattgatca gcatcttgta aaagaaaatg aaacaccaaa agcccctggg atgaaataca
    24901 aacactactc acccgataca cgtgttctga tggtcagaga tggcgattgg tcaactgcag
    24961 ttcaatgggc aaaaaataag aagatccgtg caggtgtcat agcaagcccc gaaattgcgg
    25021 atcaagtgcg gacagatact gcagctgttt atatgtataa cgacaactca gtagaagcgg
    25081 cggctaaagg attgtttgca ggtctaagag gattagatga accaacactt ggattagatt
    25141 tgatttttgt acaagtgtat ccagaaactg gattggggaa tgcttacatg aatcgcttga
    25201 aaaaagcagc aggacaaaat tattttgaaa aatgatcaat tggttattgt cgcattcttt
    25261 tagtatgata caatgctatc aagtaaatct tctatcagtg aacgaaaaac taagcgtaac
    25321 taatcgtaat agaagagata cgaatatttg gcaatttgtt tttgatggga aaaataaaat
    25381 tgtaggaaaa taaaaaggag ctgttgtttg tggtagatta caaaacgttt gaccctgatc
    25441 tttgggctgc gatcgccaaa gaagaagaaa gacaagaaca taatttggag ctgattgcct
    25501 ctgaaaactt tgtctccgaa gcagtgatgg ctgcacaagg aagtatcttg acaaataaat
    25561 acgcagaagg ttatccaggg catcgctatt atggtgggtg tgaatttgtc gatatcgttg
    25621 aaaatttagc gattgaccgt gcaaaagaat tattcggagc gaaatttgcg aacgtccagc
    25681 ctcactccgg ctctcaagcc aacacggctg cttatctcgc tttggtagaa ccaggggaca
    25741 cgatcttagg aatggatctt tccgcaggcg gacatctaac acatggatca ccagtcaact
    25801 tcagtggcaa aacctatcac tttgttgctt acggtgttga tccgacaaca gaagttattg
    25861 attataatgt ggtacgtatt ttagctagaa aacatcaacc aaaattgatc gtagcaggtg
    25921 ccagtgctta cggacgaacg atcgactttg cgaaattcag agaaatcgca gatgaagtag
    25981 gcgcaaaact gatggtagat atggcacata tcgcaggatt agtagcagca ggacttcatc
    26041 ctaatccagt tccttatgca gatatcacaa cgactaccac tcataaaaca ttgcgtggcc
    26101 ctcgaggcgg catgattttg acaaacgatg aagcattagc aaaaaaaata aatagtgcgg
    26161 tatttcctgg tattcaaggc ggccctctag agcatgtgat tgcgggtaaa gcagtagcat
    26221 tcaaagaagc attagatcct gcatttaaag aatatagtga acaaatcatc gccaatgcaa
    26281 aagcaatggt caaagttttc aatcaagcaa ttggaaccag agtcatttca ggggcgacag
    26341 ataatcatct gatgttgatc gatgttcgcg agttaggtat aaatggaaaa gaagcagaga
    26401 gcattttgga cagtgtgaat atcactgtaa ataaaaactc gattcctttt gaaacactaa
    26461 gtccattcaa aacaagcggt attcgaatcg gcacgccagc aatcactact cgcgggttca
    26521 aagaagaaga tgctgtaaaa gtggctgaac tagttgtcaa agcattacaa gcaaaagatg
    26581 ataacgctca actagacgaa gtcaaaacag gtgtacgcga attaactgaa aaatttccgt
    26641 tgcataaaaa ataaaaattt aaattccatt agtaaacaga aaagttcaat gttgggcttt
    26701 tctgtttatt ttttgggaaa acggattctt tgacaatatc ggtgatgctc tctagtatat
    26761 gaggtgtaat tttagtcttc acactaaatc tcagggagga aaagtcatga ctgatcgtat
    26821 ctcgttagaa aaggaagcag tagcattcag tgatgcaaat gcgcctcatc cgcgtatcta
    26881 tgaactagca ccggaagaag gaagagtttt actagaagaa gtacaagaat cacctgtgaa
    26941 caaatattcc gtcgatattg aagacttgat ggtggatact ggcgaatggg gaaaactcaa
    27001 tattcgtctc gtacgaccag aagggaatat ggataaatta ccagttattt tttatattca
    27061 tggagcaggc tgggtttttg gcagtgctca aacccatgat aaattgatca gagaacttgc
    27121 ggttcgtacg aattccgtcg ttgtctttcc agaatatagt cgatcaccag aagcaaaata
    27181 tccaacagca attgaacaaa attatgctgt gttgcaacag ctgaataaat tagccaagtc
    27241 aaaaaatctg gatctcgaga atctaatcgt tgcaggagat tcagtaggtg gtaacatggc
    27301 tacagtcatg acgatcttaa caaaagaacg aaagggcctc ccaatatcca agcaattgct
    27361 gtattatcca gtcacaaacg ctgattttga tacagattcc tatcatgaat tcggagaaaa
    27421 ctattttttg acaagagaag gaatgatgtg gttttgggac caatatacga cgaatgaaga
    27481 agagcgtgct gaaatcacag cttcgccttt gagagcaaat ataaatgaac taaatgatct
    27541 tccttcagca atgattttaa cgggagaagc ggatgtatta agagatgaag gtgaggctta
    27601 tgcgcgcaaa cttcgtgatg caggggttcc tgttacacaa gtacgcttcc aaggaatcat
    27661 ccatgatttt gtcatggtaa atgctatgga tcagacaaag gcaacgcgtg cagcaatggc
    27721 attatctact tcttggatca agaaaaaaga ataagctttg cttgtccgca ggaaaacttc
    27781 ttttcaaaaa cggattttct taggaaaaat ggcgagtttg actagtcaat cacttgattt
    27841 tgttttacaa ttaaaaagaa acgacagaac aaaggagagc ttaaaaaatg ggcaaatttc
    27901 aagtgatcga tcatccattg attcaacaca aactaactat tattcgggac aaaaactgcg
    27961 gaacaaaggt ttttcgtgaa gtagtcgatg aaatcgctat gttgatggca tatgaagtat
    28021 cacgggatat gccattggaa gacatcgtga tcgaaacacc gatcactgaa acaacacaaa
    28081 aaacgttgtc tggtaaaaaa gtagcgatta ttccaatctt gcgcgcaggt attggaatgg
    28141 ttgacggtat cttggaattg attccagctg ctaaagtggg acatatcggt ctttatcgag
    28201 atgaagaaac attggaacca catgaatatt tcgtcaaact tccagaagac attgatgcac
    28261 gtcagttgtt tgtagtagat ccaatgttgg caacaggcgg atcagcaatc atggcaatcg
    28321 atgcattgaa agaacgtggc gcgtcgaaca ttaaatttgt ttgtttggta gcagcacctg
    28381 agggagtaaa agctttgcaa gaagcgcatc ctgatattga catctataca gcttctctag
    28441 atgaaaaatt gaatgaacat ggttatatcg ttcctggact aggggatgcg ggtgaccgtt
    28501 tgtttggtac aaaataagta aatacgaaaa agggtgtgac acaacttttg tcacatcctt
    28561 ttttggtcat ttttaacgtt tgatgcagaa cagctttttc acagctttcg tttgcatata
    28621 aaaaaaccat cccaaaaatg cagagatggt caaattcaaa tcttttttag ttctttgtag
    28681 ttaacgatta ctacaccctt actttgcgtc atcaagttcg cattttctgc agtttcatca
    28741 atctcaacaa cagcggaatt tttcaattgc tttgaaatcg ttccagtttg cgacttgccg
    28801 tgaattgtga acattacgtg agtattgatc ttgaattttt caccaatttc cgatggtacg
    28861 atagttgtat caaattttcc aaaagttgcc attttcataa aacctgcctt tcacatcaat
    28921 tataccacgt tttatgaaaa atatcatgaa attaaactaa ttttccatcg gactctttac
    28981 aatcagccaa atagagtata taatttcttt tggataaggc cagcttagct cagttggtag
    29041 agcaacgcac tcgtaacgcg taggtcgtag gttcgatccc tatagctggc attaaaagag
    29101 aagacagata tatcaaggat ttttaatcca ttgatacatc tgtctttttg tttaaaggaa
    29161 ataaagtatg ctttcttagc aatagagcat gtattatttc tataaaaatt taggagaata
    29221 aaacgactag caatatagct gtgaaatcaa atatcacatg aactgcccaa cttgtaatga
    29281 tcgagttgct tttaatggca gcttggttga ataacaatct tgccacccct tgtatcaaaa
    29341 ggatgtgtgc tacagtgtgt aaaatatttc cattatcata agtactgtaa tggataaatc
    29401 caaagatgat tgctgacaag aaactagcga caggaatgct gaacttacta gaaaaaatag
    29461 cgagaaaata cactgagaac aattcttctc caagtatcat gataggcaaa ataataaata
    29521 ataacgggct gaaagcctca tttattggat tgcctgttaa accccatttc aaaatttgtt
    29581 gcaaaaatac cgagactgcg gcactgatta ctacattgat aaaaaaatat ttggctatat
    29641 ttttgacagg agcgacaggt ttcgagaaca tttttttcgt atctttttta ccaaaaacaa
    29701 gtgtaaatgc tataaatcca gtgatagtta aagaaaaaat gctaataatg gatggcgcaa
    29761 atagcaaccc taacaaaccg agtacaacga caatagtgcc caatatccct tttttaagtt
    29821 ctattttttt tcctaaaatg ttattcatga taataactcc tactattcag tttttgaaga
    29881 tagagtcagt atacatgaag agttaaaata ggcaatgttt ttttatggat atttgtattg
    29941 ctaaaaattt atcttatata ttcattttga ttatactact tttatttgta aaaattttct
    30001 agcaaaacca agtgcttgca actgattaag cgtacaattt tttagatgtt ccgagcgtac
    30061 ttcaatcatt tcaaaggagt tgctacttaa atcgatattt tttaaatcag tatcaaaaaa
    30121 gctagcattt tctaaatcat tagtagaaaa cattatttta gtgagggaac agtctacaaa
    30181 atctgcgctt gataagacag agtgctcaaa ggtactttct tttatgtttg aaccagataa
    30241 atttacatag tccattttac aattctcgaa taacgtgttc ccaatataac tttccatcaa
    30301 tttagtacct gttaatttac aattgacaaa tttcacgcga tgcaacatgc tttttgtcaa
    30361 tatacagcct gaaaaatcac agttttcgaa tatacagtcg gtaatctcca ttctttgaaa
    30421 atcattggaa gcaaaaaatg catacttgaa aatagatttg taaataattg gatggcagat
    30481 tatttggttt tcgatgacct ctttttgtga aaggatatta tacagttcaa aatcttcgtt
    30541 ttcatagata tgaaaaaagg atcctttatt caagcttgct tcattaactt taggaaaaat
    30601 catatttaat tacctccatt ttcataaagt catattaaca aaagctaaac caacttacat
    30661 tagcagaaaa tgagataggt tttcgccttt ttcgataacg atagtgtcgc tatctcttga
    30721 aacgttctta gaattgccct gagagacaca aattaggcgt aattctaata aaaatcttag
    30781 aataaaaatt tttactgatt taatttagaa tgtttttaaa ataaaaatcg ttgccataac
    30841 agtgtattga aaggttttaa caatccagta atgatttaaa aaaatctaga tgtagcgtat
    30901 actttgttta tagaatgtag tgggaagaaa tatatttttg ggaggaaatc gtgatgtcta
    30961 aaagtgaaga aatagaaaac atggtactaa aattatatga tctcgtttta aatccagaga
    31021 tcaaagaaaa ggaacgtata cttttgatag acgcaaagac aggcttagaa aaaggtcagt
    31081 attatcctaa agtcataaat aatttggaac gtagtttacg tccgttagca atcaggggag
    31141 aattgtctaa accagtatca ccgttttata tggagatatc aacaatagga aaatttgaaa
    31201 aagaattagg tcgaggaatg gcttcggcac cgattacttt tgggcattta taaaaacgag
    31261 ttattcatct caatgaatta aaaagtatag tcaatctcat aatgcaggct aggttcattt
    31321 atttgaacag agtctgtatt tttttattct aaataaagaa acagatgttt ctttatattg
    31381 tattttatcc tttaattaac acaaaaacag ctagtataaa ctaataatgt taattaaaag
    31441 tgtattttat gaaactatcg ttatttatta atgttgcatt tttgtaagtt aaaaattgga
    31501 aatatagatt gaaaaaatga aagcaataag taaaataaaa tgaatatatg cgaaaaaata
    31561 atttacatta ggaaaaacct tgtaaaaaca gttttttggc atatttattt tttataaata
    31621 tttgtaaaat aactatcaat tttttagtta aaagattgga aatgagtggg ggaggaattg
    31681 aagaaaggat ttttgagaga tgatatagta ggttttattt ttagttaaaa taggggagat
    31741 agaaaaaatg aaaaagtgta gaaatattat tttatcaatg ttatttatta ttactaatat
    31801 aacatcactg attcctgttc atgtctatgc ggatgcaggc agagatatca gcagtaatgt
    31861 cacttcgttg accgtggacc caacgaatat tacagatgga ggaaacataa aagtaaaatt
    31921 ctcgtttgac gaaaaaaaac aaaatatcca accaggtgat tatctttgga tcaattggcc
    31981 aagtgaagga aatattcgcg gtgaaggatt ccaaaaagaa atcccattaa tgattgaaaa
    32041 taaaaatgtt ggaactttaa cggtcagaaa agattctgcg caggttgtgt ttaatgaaaa
    32101 tattaaaaac ctagactcag tagaaggttg ggggcaattt gagatacagg ccagaaacgt
    32161 aaccgatacc ggtgaagaaa atacgggacc attcaccgtg acgagcggtg ataaaacagc
    32221 tactgtaaat gtgacaaagc cagcttctgg ttcttcttct agcgtttttt attataaaac
    32281 aggagacatg ctacctgaag atactaagca cattcgatgg tttttgaata ttaacaataa
    32341 cggcacttat gttgaacaac cagttaaaat cagtgatgaa atccaaagtg gacaaagatt
    32401 agatccaagt acgtttgaaa ttaatcaaat acacttaggt gaacagaagg tttatagagg
    32461 agaagaggga atccaacaat ttttacaaga tttccccagc gctacattta atttttcagt
    32521 aactgataat tacattgaaa taactatacc aaaaaacttt gtcaatctta ggaaaataat
    32581 ggtgagttat aagacgatca tagaaaaccc agaacaaata aattttgaga atcattcgga
    32641 agcttggttt aaagaattta ataaacctgc tgttgatgga gaaagtttca atcatacagt
    32701 taaaaatatt tcagcttctg gtggagtcaa cggtacagtt agaggcgaat tgaagatttt
    32761 caaatatatc aatgacacag agattggtat cccaaatgtg actttcgaat taagacgagc
    32821 agatgaacag cctattcaag gacagtctag tatcctgttg acttcgaatg aacagggaga
    32881 agctagtatc aaaggcctgc aagtaggaga ctatgttgta aaagaaaaag aagcacccaa
    32941 ttggattgat tttgatccac taagttcaaa tgaactcaaa ttctccataa acgaaaatga
    33001 tacagaggga gtcagtttac ctatttataa caagaaaaag gttacgaaca tcacagcaac
    33061 taaaatttgg aacggtggaa ccactccaag accgagtatt tattttaaat tattcagagc
    33121 aagtacaaac aattgggaac cagttcctga tgcagaaaca aaacgattag acaatggaat
    33181 aacttcagtg acttgggaag atatccaaca gtatgatgat agtggaaacg aatatacgtt
    33241 taaagtgcaa gaagtagatc aaaacggaaa tgattatgtc ccttcaggtt atcaaaaaat
    33301 tgaaaacggg ctagtcgtta caaatgagaa taaagaagtc atttcagtct caggacaaaa
    33361 aacatgggaa gacaatgaga accaagacgg caaacgaccg acgacgatca cagtaaatct
    33421 attagccgac ggtcaaccga tccaacacaa agaagtaagt gaaaaagatg attggcgcta
    33481 tcgtttcaca aatctgccaa aatacagaga cgggcaagaa atcatctata ctgtaacgga
    33541 agacaacgtg cccgaataca gtacgacgat tgacgggtat aacatcaaaa acagttatac
    33601 accggaaaaa acaaatatat ctataccagg tagccatata acaccgtgga aaaattttcc
    33661 agagaagaca gagagagaga aaattagaaa tctattctct caaaaattgc aaatatttgc
    33721 tcatacagga gaatccagcg aacaaagaag caattatatt agtaagagag ctgtacctaa
    33781 acagataaca aataaatcaa aaagcattct tcctaaaaca agtagtaaaa aatctagttt
    33841 tgctgtaatc attggtttat tgatagtaac tatctgtgct gggatattct tacaaaaata
    33901 taaaaaagtt tagttagaat ataatatttt ttgttaaata tgactgaaat caaaagaata
    33961 aaattccgat ttataatcga aaaaagaagc atttttatat atgcttcttt tttcgtagaa
    34021 tcaataaata tggatttggc taactatgga agaatactcg tattagtttt cagcgttcat
    34081 actagttgtt acattgtttg attggccaaa agaatttctg atatattttg tgctaaataa
    34141 agaaaaagac gcttgaattg ggaaataaga aaactactct atcattacaa attttcataa
    34201 actggcagat gttctaagta aacaagtatc ttttcaaagt cggaaaaatc cataatcaac
    34261 gtagtggtat tgatatttgg atgaaagcct acggtatctt gacgatcaat agcagcatcg
    34321 atcacgactt ggattttttt ctctttgtcg tgcatcaatg ctaatggagt cactgtacct
    34381 gctggaacgc ctaggaggtc aggaagctgt tcttcagaaa caaaagataa gcgcttttct
    34441 tttaattgtt cagctagttg ttttaaatcg gcgtgctttt catcaggcaa gatgacaaga
    34501 tagatttgtt ttccttttct tgatttcaat aatagatttt ttacttgcgg accaggtagg
    34561 gaaaaaggga catttttgac tgacgtaatc gcaggatgat cgactttttg aaaagagata
    34621 cccagttttt ttagtagttc ataagcttct tgttcggttg cacgactcat cgcgcatcac
    34681 cctccttttt ttattagtgt atcataaaaa agagttgaca aatgaaaaat aatcatgtaa
    34741 attacacgta aagttaaaac aaatgacatc gaaaagaaga gtagccgtta ggtgttttta
    34801 gagagtctct ggttggtgga aagaggcagc agttaaccgt gaaacacatc ttggagtcga
    34861 ttttctgaag cgtatagtag gaaaatccgg ggagcccgtt acagctgcgg tcgttgctag
    34921 atgaccagat aaggctggct tttccgtgag gagtcggtaa aaaaaggtgg aaccacgtga
    34981 ttaacgtcct ttgatcttcg gatcaaagga ctttttgttt tcatctgaac ggcaacgact
    35041 gtgtgaggtt ttttctgcaa ggaaaaaata aacagaggtg gaaccacgta taatacgtcc
    35101 tcttggcatt tgccaagagg atttttttat tttaaaggag gaaaagaaga tggagtattt
    35161 gattgaagtt atgccgcaat tattagtagg agcactcaca acattgaaat tatttttatt
    35221 taccttgatt ggctcattac cattagggat tgttttagca ttaggattgt ctttgcattt
    35281 taagccgcta cgctacttgc ttcaaacata tgtatgggtt atgcggggaa caccgctgtt
    35341 gttgcaactg atttttattt tttatgggtt gccgacgatt gggatcgttt ttgatcgttt
    35401 cgaagcagca ctcattgcct ttatcttaaa ctatgcagct tattttgcag agatctttcg
    35461 tggagggata caatcgattc ctcaaggtca atatgaagca gcgcaagttt tgcaattaag
    35521 tccctttcaa acggtgacga aaatcgtcat cccacaagtg acaaagattg ttttaccttc
    35581 tgtagggaat gaagttatca acttggtcaa agattcttcc ttgatctata tattaggttt
    35641 aggtgacgta atgcgtgctg ggaaaatcgc gatggaacgc gacgcgactt tactgccttt
    35701 gctaggcgtg gcaatcatct atcttacatt gactggtatt ctaacaatcg taatgaaaca
    35761 agttgaagga aaattaaatt attaccgcta actgatagga ggaagaaata tgattgaatt
    35821 gaagaaagtg aacaaagcat ttggtgaaaa aaaaataatc aaagatttga atctaatcat
    35881 tccagatggg aaaacattag ctatcgtagg tccttccggt ggcggtaaaa ccacgctttt
    35941 acgtatcttg gctggcttag aaagttctga cagcggagaa ttttatttag acggtgtacc
    36001 gttcaaccca ttcgagctta aaatgaaaga acaagttgta ggagtcgtat tccaagactt
    36061 ccagctattt ccacatctga atatttttga aaacattacc ttagcaccaa aaatggtatt
    36121 gaaacagaca aaagaagaat acaccaaaaa agcagaagaa ttagcggctt cattagggat
    36181 tagtgattta ttgaatatct atccttatca gctttctggc ggacaaaaac agcgggtagc
    36241 gattgccaga gcattggcta tgaatccacg ggtattggct tatgatgaac caacaagtgc
    36301 tttagatcct gaattacgcc agcaagtcga gcgtttgatc ctatcattga aagaagatgg
    36361 ggtaacccaa attattgtca cccatgattt agtatttgca gaaaatgtcg gtgatcaatt
    36421 actaaaagtt tccccaattc attaagaaag gagaagatag agatgaaaaa aaccagtttt
    36481 ctattcgctt tgatcgcagg tcttcttctt tttgcaggct gttcgaacaa aaaaacttca
    36541 gcagataatt gggcgactat caacgaagag aaaaaaatcg ttataggttt agacgataca
    36601 tttgttccta tgggatttag agataaagac gggaagctca caggatttga tattgattta
    36661 gccaaagcag tctttgaaca atatgggatt acggtagact ttcagcccat tgactggtca
    36721 atgaaggaat ttgaactgaa caatggaacg atcgatttga tatggaacgg ctattccaaa
    36781 acgccggcaa gagaaaagaa agtgcaattt acaaaacctt atatggaaaa cgatcaagtg
    36841 ctgatcacac ctaaagaatc aggaatcaca aactttggac aaatgaataa taagagatta
    36901 ggtgcgcaaa atgggtcatc tggttatgat gtatttacga aacaaccaga agtattaaaa
    36961 gagatagtca aaaaccaaga tgctgttttg tatgatagtt ttaatgaagc attgatcgat
    37021 ctgaaaagca gacgggtcga tggtctgctg atggataaag tatacgcaga ctattatttg
    37081 aaacaaagaa acgaactaga agacttcaac ataacaaaag gttcttatga gagtgaggat
    37141 tttgcagttg gtgcacgcaa gtcagatagt acattagtga aaaaaatcaa tgaagcccta
    37201 gatcaactag agaaaacagg tgaattccaa aaaatatccg ataaatggtt tggcgaagat
    37261 gttacgccga gaaattaaca aataggggac tgtgacaaaa gacgtgtcac agtccctttt
    37321 tccgaataaa cagtgttctc ctgccaactc cttgtgactc ggagctgaat ggcaggctca
    37381 caacctcttg gtaaacggtg ttcaaaagcc agtttttcgg tattaagcca aatttatgca
    37441 aaaatgtaga aagccatttt cacaaaattt ttcttactac tcgaaactaa gcgacttttt
    37501 cacaacctcc tttacatatt tttattttgt tgtggaaggg gtttcgtgtt attctaaaag
    37561 aggaacgatt gaaggttata ggaaaggaag agatgaatgg aacacaaaga acttacctca
    37621 tttccaaaag attttctgtg gggctctgct tctgcagcgt atcaagtaga aggagcttgg
    37681 caagaagatg ggaaaggaga atcagtctgg gatcgatttg tacggatacc tggaaagaca
    37741 tttaaaggaa cgaacggtga tttggcagta gaccactatc atcgttataa agaagatatt
    37801 gctttaatga aagaacaagg tctgaaagct taccgcttct ctgtagcttg gacacggatt
    37861 tttcctaatg gacgaggaga agtcaatcaa gctgggctcg ctttttatga gagattgatc
    37921 gacgaattga ttgaaaacga tattgaacct atgttgactt tatatcattg ggatcttcca
    37981 caagcattgc aagatgaata taatggttgg gaatcacgtc agatcattga agatttcact
    38041 cattatgcag aaacattatt tgaggcattc cgcgggaaag tccattactg gattagtttg
    38101 aatgaacaaa atatcttcac ttcattaggt tatttgttag cagcacatcc gccaggtgtg
    38161 acagacccga aacgaatgta tgaagttaac catattgcta atttagcaaa tgcatctgtc
    38221 atcaataaat ttcacgagtt agaaatgcct ggaaaaatcg gaccaagctt tgcgtatacg
    38281 ccaaattatc caattgacag taatcctgaa aatgttctgg ctgctgaaaa tgcagaagac
    38341 ctgatggcca attattggat ggatgtctat atgtggggaa aatatccgat tgctgccatg
    38401 aggttcttag aagaaaaagg atgggcacca acgattgaag ctggcgatgc agaattgcta
    38461 gaatctgcta aaccagattt tcttgggatc aattactatc aaacggcgac gaatgcattc
    38521 aatccattaa acggagttgg tgctggaaaa atgaatacga caggaaaaaa aggttcatca
    38581 gaagaaactg gagttcctgg aatgtataaa aaagttgaga atccatttgt cgaacgaaca
    38641 aattgggact gggagattga cccagaagga ttaaggatcg gactgcgtcg tatcacaagc
    38701 cgttaccgca tgccggtact gattacggaa aatggcttag gagagtatga caagttgaca
    38761 gaagataaac aaatccatga cgactatcga atcaattact tacaaagcca cgtcaaagcc
    38821 atcaaagaag caatttcgga tggagcagaa gtcctaggct attgcacctg gtcttataca
    38881 gatttgctta gctggctgaa cggttatcaa aagcgatatg gatttgtata tgttgatcaa
    38941 gacgaaacac aagaaggatc tttggaacga tataagaaag acagttatta ctggtaccaa
    39001 aaactgattg aagaaaatgg agagaacctt tagttcacat acttaaaaca agaaggtacg
    39061 gctggatatg gccgtgcctt ttcttgataa aatcatttag aaattaagaa aaactgtaaa
    39121 ataagctgaa aaatgaaaga aagcgtcagt tctttcaaac aaaactttag ttcccttact
    39181 tttttttgta taatgaaact tgatgaaatg agggataata aatggcacaa aagaaacggc
    39241 ctactaaaaa aaggaaaaag acgaaaaaaa cgaaaaagca aaaacagcag caggaacaaa
    39301 tgctgacgat tggtgttggg tttgccttga ttttatttgc tgtcttcggc tttttaaaat
    39361 taggtttttt aggaatattg attgcaaacg gctttcggat cattgcagga aatacttacc
    39421 aaatcctctg tcttttatta gccgtattag gattttggat tgtcattaag aatacagagt
    39481 tttcaattgg taaaaaccga cgctggtttg gcggcatact cttttatttc ggtatcttat
    39541 tattgttaca tgcccattta tttggcaaac tccatactgg ggaaccaaat atcatgggga
    39601 cgacatggga tttgttagcc agtgatataa aacaaagtca agtagacaat aacgttggtg
    39661 gtgggatgat tggagcaatc ctttatcatt ttacttactt cttgattgca cagcctggaa
    39721 gttatttagc agcagtgcta ttactggcag gaggagcatt cctgttcagt aatctggaag
    39781 gctatcagct gttaaatggt atccaatcaa ttggagaacg agtacaggaa ttattggaag
    39841 gtgatcctgc caagcaagct cgaaagcaag cggcaaagga agagagaatg aaacagcgcg
    39901 cagaagcgaa agaagcaagg cgcttagctg caaaagaagc tgcagaaaaa gaagctgcag
    39961 aatatgagaa gaaaaaagcg gtgagccagc aaagggaaaa tactgctgat gaatggcagg
    40021 aaccagaaaa tacagagccg gagcagctaa gttttgttcc aatcgacagt tttcaagaaa
    40081 atatccatcc tgcgaatcta gagaaaccag taccagatac accaaaacag accaatacag
    40141 cagaaggttt ttcagatgag ttgccagagg atgacggtac ctcattagaa tttgagattg
    40201 aagcagaaca ggaaaatcaa gactatgaat taccgacagt tgatttgctt gattctatac
    40261 caactgtgga tcaaagtgat gagtataaaa aaattgaaaa aaatatcggc gtattagaac
    40321 aaactttcca aagtttcggt gtcgatgcca aggtcgtcaa agccagctta ggaccatccg
    40381 tcacaaaatt cgaagtccag ccggctgtag gggtaaaagt aagtaaaatt gtgaacttaa
    40441 cagatgatat cgcgcttgct ttagcggcga aagatgtccg gatggaagca ccgattccag
    40501 gtaaatcact gattggtatt gaagtaccaa atggaaagat cagtatggtt tcctttagag
    40561 aaatcatcga agcacaacca aaccacccag ataaattact agaagtacct ttaggacgtg
    40621 atgtttctgg acgggtacaa acggctgatc tttcgaagat gcctcactta ctcgtggctg
    40681 gttcgactgg tagtgggaag tcagtagcaa ttaatgggat tatcacaagt atattaatgc
    40741 gtgctaagcc ccatgaagta aaactgatga tgatcgatcc gaaaatggtt gaattgaata
    40801 tgtacaacgg catacctcat ctgttgacgc cggtcgtgac gaaccctaga aaagcagcgc
    40861 aagccttaca aaaagtagta caagaaatgg aagaacgata tgaaaaattc gcggcaaccg
    40921 gagtaagaaa tatttctggt tacaatgaat ttgttcaaca gaaaaacttg gaaaacggaa
    40981 cgaaacatcc aaccttacca ttcatcgtag tgatcgtaga tgaattagct gatttgatga
    41041 tggtagccag caatgaagtt gaagatgcga ttattcgttt agcgcaaatg gctcgggcag
    41101 cggggattca tatgatccta gctactcaac gtccaagtgt ggatgttatc acaggaatca
    41161 tcaaagcaaa tgtaccttcc agaatggcat ttgcggtatc aagcggtaca gattctcgga
    41221 cgatcattga ttctaatggg gcagaaaagc tcttagggcg aggagatatg ctattcttgc
    41281 caatgggtga gaataaaccg atccgtgtgc aaggagcatt catttctgac cacgaagtag
    41341 aacgggtcgt tcaatttgtt acagatcagc aagaagctca ttatgaagag aaaatgatgc
    41401 cgacagatga agttgaaacg acaggtgctc cagaacagcc acaagatgag ctgtttgaag
    41461 aagcaaaagc acttgtcgtt gaaatgcaaa cggcaagtat ttcccttctc caaagaagat
    41521 ttcggatcgg ttacaaccga gcagcacgtt tagtagatga actggaagct catggagttg
    41581 ttggcccgtc agaaggaagc aagcctcgga aagtattcat tgagcaggaa gaaacatcag
    41641 aaacgttgcc ggacgataat gacatgtaaa acttgtgtga tgaagggttg aaaaacgaat
    41701 aaccaataaa aagacaaggc atgatgatac caaaagaaaa aatggttttt ttccatcttt
    41761 tctaatacgg tatgatgtct tgtcttttta gtttttgtga gattaaagtt ctattcgatt
    41821 tatttgtgaa gtattgcatt aaggaaatga atcatgtata gtatgtagcg aaactttgag
    41881 aaaaagaggg aaaatacttt ggaaaaacag tccatttatg gcttgacgaa tgaagaatta
    41941 atcaattggt ttatagaaaa cggcgagaaa aaattccgag ctgcccaagt ttgggaatgg
    42001 ttgtatcaaa aacgtgtaag taatttcaca gaaatgacga atctatcgaa acaattgatc
    42061 gaaaaattat cggagcattt tatcatcaat cctctaaaac agatggtcgt ccaagaagct
    42121 tcggatggta cagtaaaata tttgtttgaa ctccctgata aaaacatgat tgagactgta
    42181 ctgatgagac aagaatatgg cttgtcagtt tgtgtgacga cacaagtagg atgtaatatc
    42241 ggctgtacgt tttgtgcaag cgggctgctc aaaaagaacc gtgatctgac tgctggagaa
    42301 attgttgcac agatcatgat ggtccaacat tattttgatg agcgcaatct tggcgaacgc
    42361 gtttcacatg tcgttgtaat ggggatcggt gagccatttg ataattacga caatgtaatg
    42421 gactttttgc atatcatcaa tgatgccaaa ggattggcaa ttggtgctcg gcacattaca
    42481 gtttccacta gtggattagc acacaaaatc aaggaattcg ctaataacgg cttgcaagtc
    42541 aatctggcta tttccttgca cgcgccgaat aatgaggtgc gaacatcgat catgcggatc
    42601 aaccgaagtt tcccaattga gaaattgatg gaagctgtgg atgagtattt agagaaaaca
    42661 aaccgtcgaa tcacgtttga atatatcatg ttgaatcaag taaatgatag accagagcat
    42721 gcgcaacaat tagcagatct attaaaagat aagaaaaaat tagcatatgt caacttgatt
    42781 ccatataatc cagtcagtga acatgatcaa tattctcgca gtccaaaagc tgatgtattg
    42841 agattttatg atgtattgaa gaaaaacggc gtaaactgtg tgatacgtaa agaacatggt
    42901 acagatattg atgcagcttg cggacaattg cgaagcaagc aaatgaaaaa aacagttgcc
    42961 aaataatcgt atcctactcg ttttttcaat taccataaaa ggagcagttt tcttaattaa
    43021 ggaactgttc aacttaaata agagaaaaga ttctatagcg aaagctataa agcttttttt
    43081 gacaagaaaa accctcatca agcaaagaaa tgtcctcaat ttgatgacag cctgcttgat
    43141 gggggtttta gcaattattt aactgatttt cttatatcct tgctggcttt cttgtgtagc
    43201 atgataagtt tctacgtcaa gaatggcctg tttaaatttt tctcgggtga tttcataagg
    43261 cacatgttta atatcatttg ttgccatggc tttatctaag attgcttcta aatcggtcgt
    43321 gacattgaga ttcatgtcgg ttaacgatac tggaagttgg ttctttttca taaacacata
    43381 gattttatca aacaaatcga actgctgatc catcatcaat aaggtcagta caccataact
    43441 gacagatgct ccgtgaaggt atccctccat tttttctaga acagtcgtac cgtaatagaa
    43501 tgagtgtgcc atagcagaat tatagttatt gttaactaaa acagaaacca atccggtagt
    43561 aacaatgata tccgaaacga cttgttcaat tgcatatgag ggacgatcgt cggcactatc
    43621 tttcaatgct tgcgtaccat aagtcaagag acgatcaatg cacatttttc cgatttggat
    43681 tcctaatcta tccgtgtagc ctagatcatc gccacgagca gaaaaagtag attcgacttc
    43741 tttggataaa gcatcgccaa tacctgccca taagtattta tcaggtgctt cggcaataat
    43801 tgctgtatca atgaaggtgt gtacaggtgg ttttgaagga aagaagagtc cgtccattac
    43861 gccttcttcg ttatagatga cacataccgc agtgacgggc gaacagttcg aaccaatagt
    43921 gggaaaggtg aagactggtt tagctagttt ttcaccaatg acttttacag tatcgcaagc
    43981 acggccacca ccgactgcaa acaggacgtc tgctttttgg acactttcat gctggatcaa
    44041 ctgttcaata tttccataag ttgaattacc cccgtaccag agactggcga caacctctat
    44101 ttcctgtgtc aaagctactt ttattttgtt ttctgccttt gaaagtgcag tcttccctcc
    44161 aatcagcact acttttgtcc catattcttt gacgattcca tttgcttttt catacgcatc
    44221 tgttccaatg gtataatttg gtaagaaaac actttgactc atattcattt ccttctttct
    44281 tcgttgaaac gggttaaaat tttaaagagt gatcgatctg actgcggctg tagatggagt
    44341 agaggtgaac ctaagacagg ataagtgatg aataaggtgg catgaacacc ttgaaatcat
    44401 caataagtat cctaaaaacg aacaagtaca aaaacattga aaacgacaat aatgaatttt
    44461 tgttcctctt agtatttcta ccgattccct ttgctttttt gtaattatct aaaaattcta
    44521 aaaattaaga ttattatatg aaaacaggtt ttatttgtca attcataatt ggtttttttt
    44581 aaagcaaaag ataatctata tcatgatgaa caaacagagt tttttcctcc aattgatggc
    44641 tttcctgatc tttcctattt tgaataaagt gtttctgtat aattttttta ttttataagt
    44701 aagataaata atgaaagaat agagatactg attggtagct aaagattttt gagcgagaac
    44761 atttcgtttt ttcaaaagga ctgttagaat aagcaagaac aagggggaag acgtatgata
    44821 atcagtgaat ttgaccgtaa taatccagta ttgaaagatc agctttctga tttactgaga
    44881 ctgacttggc cggaagaata tggagacagc tcggcagaag aagtagaaga aatgatgaat
    44941 ccagaacgaa tcgcggtagc agcggtagac caagatgagt tagtaggatt tattggtgca
    45001 atccctcaat acggtatcac aggttgggaa ttgcatccat tagttgtaga aagctcccga
    45061 cgaaagaacc aaataggtac tcgattagtc aattacttag aaaaagaagt agcttccaga
    45121 ggaggaatca cgatttattt aggtacggat gatttagacc atggaacaac gttaagtcaa
    45181 acggacctgt atgagcatac atttgataaa gtggcttcca tccagaacct tcgtgaacat
    45241 ccgtatgaat tctatgaaaa attaggttat aaaatcgtag gtgtcttacc aaatgcaaat
    45301 ggctgggaca aaccggatat ttggatggca aaaacgatta ttcctcgacc aaattctcaa
    45361 taataaaaag aggttgtgac agaagtaatc agcttcaaga aataagaagg aatttacgaa
    45421 aattacttct tgaatttttg tgaaattcca acttatttcc gaagaagcta cttttggaac
    45481 accgtgtacc agaggttgtg aaaaagtcgc ttagtttcga gtagtaagaa aaattttgtg
    45541 aaaatggctt tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa
    45601 caccgtttat tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat
    45661 tcttttttat ctttgtatgg caataataga caatataacg aaaattattt aatggctttt
    45721 ggaagaccat ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca
    45781 cgaaaaaatc attattttat gaaaaagaca aaaaaaagtg ttgatttttt aa
//
LOCUS       DBGZHO010000013        43704 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.013, whole genome shotgun sequence.
ACCESSION   DBGZHO010000013 DBGZHO010000000
VERSION     DBGZHO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.013"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..237
                     /locus_tag="ACN3HL_000954"
     CDS             <1..237
                     /locus_tag="ACN3HL_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8005847.1"
                     /translation="IDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMEFNQVNQGFIS
                     SVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(351..1481)
                     /locus_tag="ACN3HL_000955"
     CDS             complement(351..1481)
                     /locus_tag="ACN3HL_000955"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HHC8005848.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKE
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1541..1768)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2130..3332)
                     /locus_tag="ACN3HL_000956"
     CDS             complement(2130..3332)
                     /locus_tag="ACN3HL_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8005849.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3392..3595)
                     /locus_tag="ACN3HL_000957"
     CDS             complement(3392..3595)
                     /locus_tag="ACN3HL_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HHC8005850.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3737..4801)
                     /locus_tag="ACN3HL_000958"
     CDS             complement(3737..4801)
                     /locus_tag="ACN3HL_000958"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HHC8005851.1"
                     /translation="MDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERFE
                     ELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQF
                     FRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINNE
                     SNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAKI
                     ISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQSF
                     EKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYYQ
                     EEVEYYERKLQSISNEKTSY"
     gene            complement(4862..4969)
                     /locus_tag="ACN3HL_000959"
     CDS             complement(4862..4969)
                     /locus_tag="ACN3HL_000959"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005852.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            5132..5944
                     /locus_tag="ACN3HL_000960"
     CDS             5132..5944
                     /locus_tag="ACN3HL_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005853.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6318..6509)
                     /locus_tag="ACN3HL_000961"
     CDS             complement(6318..6509)
                     /locus_tag="ACN3HL_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005854.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6754..6983)
                     /locus_tag="ACN3HL_000962"
                     /pseudo
     CDS             complement(6754..6983)
                     /locus_tag="ACN3HL_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6967..7164)
                     /locus_tag="ACN3HL_000963"
     CDS             complement(6967..7164)
                     /locus_tag="ACN3HL_000963"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HHC8005855.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7310..8188)
                     /locus_tag="ACN3HL_000964"
     CDS             complement(7310..8188)
                     /locus_tag="ACN3HL_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHC8005856.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMLSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(8227..9345)
                     /locus_tag="ACN3HL_000965"
     CDS             complement(8227..9345)
                     /locus_tag="ACN3HL_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HHC8005857.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9342..11441)
                     /locus_tag="ACN3HL_000966"
     CDS             complement(9342..11441)
                     /locus_tag="ACN3HL_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HHC8005858.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLGNLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPLYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETMNYFAQLFGQLSMSDDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACSGLAEIFEALEQLSLSERYKDIACKLKESICKQMTIDGTF
                     GEQFLEGIGDEEKTTYSVKNYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDPLYQNTMTFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSDMHNH
                     QAFVTRLEELICLADLDGSWWWWPYRLEAKQGEVVRDFGCGKCGWASGLFVSIMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIYIQRRKR"
     gene            complement(11492..12313)
                     /locus_tag="ACN3HL_000967"
     CDS             complement(11492..12313)
                     /locus_tag="ACN3HL_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8005859.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12310..13119)
                     /locus_tag="ACN3HL_000968"
     CDS             complement(12310..13119)
                     /locus_tag="ACN3HL_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HHC8005860.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(13140..13634)
                     /locus_tag="ACN3HL_000969"
     CDS             complement(13140..13634)
                     /locus_tag="ACN3HL_000969"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8005861.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13646..14146)
                     /locus_tag="ACN3HL_000970"
     CDS             complement(13646..14146)
                     /locus_tag="ACN3HL_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8005862.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(14211..16907)
                     /locus_tag="ACN3HL_000971"
     CDS             complement(14211..16907)
                     /locus_tag="ACN3HL_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8005863.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17335..18408)
                     /locus_tag="ACN3HL_000972"
     CDS             complement(17335..18408)
                     /locus_tag="ACN3HL_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8005864.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18405..19232)
                     /locus_tag="ACN3HL_000973"
     CDS             complement(18405..19232)
                     /locus_tag="ACN3HL_000973"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005865.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(19233..20039)
                     /locus_tag="ACN3HL_000974"
     CDS             complement(19233..20039)
                     /locus_tag="ACN3HL_000974"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005866.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(20051..21136)
                     /locus_tag="ACN3HL_000975"
     CDS             complement(20051..21136)
                     /locus_tag="ACN3HL_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005867.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(21153..21695)
                     /locus_tag="ACN3HL_000976"
     CDS             complement(21153..21695)
                     /locus_tag="ACN3HL_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HHC8005868.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21953..22942
                     /locus_tag="ACN3HL_000977"
     CDS             21953..22942
                     /locus_tag="ACN3HL_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HHC8005869.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22939..23676
                     /locus_tag="ACN3HL_000978"
     CDS             22939..23676
                     /locus_tag="ACN3HL_000978"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HHC8005870.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23673..24224
                     /gene="coaC"
                     /locus_tag="ACN3HL_000979"
     CDS             23673..24224
                     /gene="coaC"
                     /locus_tag="ACN3HL_000979"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HHC8005871.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            24240..24872
                     /locus_tag="ACN3HL_000980"
     CDS             24240..24872
                     /locus_tag="ACN3HL_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHC8005872.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24957..25604
                     /locus_tag="ACN3HL_000981"
     CDS             24957..25604
                     /locus_tag="ACN3HL_000981"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HHC8005873.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25609..26592
                     /locus_tag="ACN3HL_000982"
     CDS             25609..26592
                     /locus_tag="ACN3HL_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HHC8005874.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26995..28509)
                     /locus_tag="ACN3HL_000983"
     CDS             complement(26995..28509)
                     /locus_tag="ACN3HL_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HHC8005875.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28647..29453
                     /locus_tag="ACN3HL_000984"
     CDS             28647..29453
                     /locus_tag="ACN3HL_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005876.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29628..30197)
                     /locus_tag="ACN3HL_000985"
     CDS             complement(29628..30197)
                     /locus_tag="ACN3HL_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8005877.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30280..32340)
                     /locus_tag="ACN3HL_000986"
     CDS             complement(30280..32340)
                     /locus_tag="ACN3HL_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HHC8005878.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32617..34095)
                     /locus_tag="ACN3HL_000987"
     CDS             complement(32617..34095)
                     /locus_tag="ACN3HL_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8005879.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34393..35328)
                     /gene="murB"
                     /locus_tag="ACN3HL_000988"
     CDS             complement(34393..35328)
                     /gene="murB"
                     /locus_tag="ACN3HL_000988"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HHC8005880.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35401..36321)
                     /locus_tag="ACN3HL_000989"
     CDS             complement(35401..36321)
                     /locus_tag="ACN3HL_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8005881.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36434..37186
                     /locus_tag="ACN3HL_000990"
     CDS             36434..37186
                     /locus_tag="ACN3HL_000990"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HHC8005882.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            38172..38705
                     /locus_tag="ACN3HL_000991"
     CDS             38172..38705
                     /locus_tag="ACN3HL_000991"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HHC8005883.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(39195..39719)
                     /locus_tag="ACN3HL_000992"
     CDS             complement(39195..39719)
                     /locus_tag="ACN3HL_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HHC8005884.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39712..40185)
                     /gene="tsaE"
                     /locus_tag="ACN3HL_000993"
     CDS             complement(39712..40185)
                     /gene="tsaE"
                     /locus_tag="ACN3HL_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HHC8005885.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(40308..41288)
                     /gene="pta"
                     /locus_tag="ACN3HL_000994"
     CDS             complement(40308..41288)
                     /gene="pta"
                     /locus_tag="ACN3HL_000994"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HHC8005886.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41441..42121)
                     /locus_tag="ACN3HL_000995"
     CDS             complement(41441..42121)
                     /locus_tag="ACN3HL_000995"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HHC8005887.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            42247..43116
                     /locus_tag="ACN3HL_000996"
     CDS             42247..43116
                     /locus_tag="ACN3HL_000996"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8005888.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            43142..43657
                     /locus_tag="ACN3HL_000997"
     CDS             43142..43657
                     /locus_tag="ACN3HL_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HHC8005889.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
BASE COUNT        13048 a         9044 c         7478 g        14134 t
ORIGIN      
        1 attgatattt atttcgcaga cccaggaacg ccttcccaac ggggattaaa tgaacattca
       61 aacggactcc tccgaaaaga tggactacca aaagaaatgg aattcaacca agtcaatcaa
      121 ggattcatct catccgttgc gtccaaaaga aaccatatcc ctagaaaatc actaaattac
      181 caaacaccat tagaagtttt tttgagttac gtaaatggaa agttttgtct cgcttaattt
      241 gacaaataat acaaataaat aatataaaag gtaaataaaa aagagtggat ttctccactc
      301 catgaaaagc cgactttttg ggacgctttt ttttgccaag cctcacattt ttatagccaa
      361 acttcttttg cgacttgctg caataattgg attttcttcc attgttcttc ttctgttaaa
      421 tggtttcctt cttctgttga agcaaaccca cattgaggac tgatacttag attttccaat
      481 ggtacaaatt gttgtgcttc ttttattcgt tcttttattt tctccgtatc ttccaaatct
      541 ggaaacttag aagtaactaa tcctaaaaca actttacttt ctttgttact ccaatgtctt
      601 aaaggagtaa aatctcctgc tcggtcagaa tcgtattcca aaaagaaacc atcataattt
      661 gttgaaaaca actcttctgc aatgggttca tatccaccgg aaaacagcca agaagaagcg
      721 tgattcccgc ggcagatatg tgttgtgatc gtcaaatctt ctggtttgtc ttccagtgcg
      781 ttattgataa tctctgtaca aatatgggcc atttctttcg gatcaatttc tttttgaaga
      841 agtgcttctc ttttagtttg atcagctaga aacgcccaat ttgtatcatc gaattgcagg
      901 taacggcaac ctttttcata aaaagcatga atcgctgctt tgtaagtaga ggacaagtcc
      961 tcataaaaat cagatagatc aggataaatc tccttgattt ttgaagaacc atcattagat
     1021 aggatctctt gtcgtaaaat catcgtggga ctagggatcg ttgcttttgc aacaaaagta
     1081 tcatctgttt ccactacttc tttcagaaaa gcaaaatctt ttaaaaatgg gtgatttgga
     1141 ttgaaagata atttatctac tacccgaata ttataagctg gtgctgcttt tccgtggaat
     1201 gtttgattat atccagtttc tggaacatag ccttcgatac catttagttc ttctaaaaaa
     1261 tcaagatgcc aaaatccacg ccgaaattca ccatctgtaa ttcctttgat gccgactgct
     1321 ttttggtctt ccactaattt ttttatttcc tggtcttcga ttgcacgaag ttcttctttt
     1381 gaaagtaagc cttcttgaac tttttttctt gcttctttga tcgattgcgg gcgtaagaaa
     1441 cttccgacat gatctactgt aaatggtcta tttttgctca tttcattcac tcttttcttt
     1501 gttttttgta aaaaaaaatc cttttactag caaatactag taaaaggacg attatactcg
     1561 tggtaccacc ttttttcaga aaaaacattc tttctctcag cctgacaata aaatcagtgg
     1621 tcttggtaac gaaagactgt tcgtttttgc ctacctttcg acaaaaaatc ctctaaggcc
     1681 attttcgaca gtcaacttct agctttttac accaaccaaa gcctctcttg aaccattttc
     1741 tgtctacttt ccttctcatc ggatactatt agaataaaat tagaatagca tgtttgaaag
     1801 aaaagtcaat agggaataag aacaaacaaa aactaatttg ttattcttag taatttgttt
     1861 gtggaataca ataaagcttt tctaatatga taattgttca gtcgtccttt catcttagat
     1921 cacttcctta aaatgatcat acccgtttca accacataaa aaaggactta attttgaaaa
     1981 atttcccatc aaaactaagt cctttttatt atagttatgc aaatttgctt attttctcgc
     2041 tatttccgat acatcttgaa caggtgcaat tcgactgaaa acactggtgc aaaagcattt
     2101 atttgtctta tggtagaacc gtggaaaact cagactggta ataaattgtc attttttgaa
     2161 agaatagcgc cctcttgaac attatcaatc gcacttacca cttgttgatc tgactttgca
     2221 tataagtgac cgtaagttcc taaagtgatt tgaatattcg catggcccaa tcgttcttga
     2281 atagatagcg gttgaatatt ctgctcaatt agaaatgcaa catgagaatg tcgtagcgcg
     2341 tgaagcttaa tcggtttgac acccgctttt ttagcagctt cttttaacca gttcgcaaaa
     2401 gaataaggtg gcgtaaatgt tccgtccaac tgagcaacat attcaaaatt tccaatacgt
     2461 ttttgcaagt cataccactg tctgagtttt aaggaaagct tcttccccaa cccaatcgtt
     2521 cgataagcac atttagtttt gggagtcgaa aagtaccaat catcttttgt attataaatc
     2581 aatgtcttct caatcgttat cgtgtttttc tcaaaatcta cattcgacca agacaaagct
     2641 tcaagttctc caatccgaat gccagtataa aagagcattt catacacaat cttccgatgg
     2701 tgggtttgaa tcttatcatc cttcaattca ttcatcactt tttgaaactc actgtgttcc
     2761 caaaactcaa ctttcttatt ctcagaagga agcgaagaaa catcttcaac gggattttta
     2821 gcaatcaccc cctctttaac agcccgatcc aatacaattt ttaggtgccc tcgaatccga
     2881 ttgatataag attttgataa cgtttcgcca ttaacttttt tccgtgaatt acgtgactct
     2941 gtctggctta gttcaaataa ccaatcctca atatcgtgac ttgtaatatc tcgaacacga
     3001 aaatgataga aaaactgcat acgcttttcg aaaatgaatt gcgcattctc atatgtttga
     3061 cttttgacct gtctctcgta ccattttaca aacctatcct tgtaaaactc ttcgaaagtc
     3121 atttgattgg tagaacacag ttgattagga attgtcttgt taaaatcatg tgtttccatg
     3181 tacttgtcat aagcaatttt ggcatctttt tgtgaagcat aacctcgttt agtcttctga
     3241 acctttcttc cattttcatc tatacctaga tacgctcgga agaaccattt ttttgtcttt
     3301 ttatcttggt aaatattttt aatttttggc atcgttccat tcctccctgt acttgagaaa
     3361 agctacttta atagtaccgc gcttgtactg tttattccgc aacttgaatg tgaaaaagat
     3421 gttcaattac tcgggatggc accacaccaa cttggcgatt attataaaaa tcaatacctt
     3481 caatccttgc aagatatgcc ttgctctctt taatcattcg tgcagcttga ctaggtttaa
     3541 agcccatctc tatcaaaatt gcacgattta ccatgaaatc acattttgtt tccattctct
     3601 cacctcctga ttctttactc cttttaaaat aatcctcttt ataatctatt gtttctcatt
     3661 cgatggttgt gttatactcg tcttgtcgag gcggagtacg ttgcacaact tgttgtgtaa
     3721 gcagtacttt gcttttttag tagcttgttt tctcatttga tatactttgt aattttcgtt
     3781 cataatactc aacctcctcc tgataatact ccgggtctgc cttcatattt tggagaagtt
     3841 tgatctgtct tggattcatt tctccttgtt caataatcaa aggcaacaag gaagaatgaa
     3901 acgtttgatc gacctgtgca ataaaaacta atgatggtga aacaccatga attaaccaac
     3961 tcatagtttt ctcaaaactt tgaggaattg tatctaaaga aatggtgatt gcgccataat
     4021 tgctaataaa ggctgcccat ttggcatcaa cttttgcacc tagatcattt ggatcacggt
     4081 cataaaaaca aattgctcca ttaagtaact caaagaacag tttggttaaa tcatgggttt
     4141 ttgaaataat ctttgccaag ctttgcgctt tctcttttcg ataccgtagt tcaaagcgat
     4201 tctttacttt tgcctcttct aaaggaattc ctcgtcgctt ccgttgttca tggtccttct
     4261 gataaaagca aaaacgacac tgactcttct ttgagcctaa atacaaggtc tcaccatttg
     4321 attcattgtt tatgatatcc gtaccgccat gagattcact cacttgaaaa gtggtccaca
     4381 catggcctag tattacctta tgcttaagtt ctggaatgct gagactcccc acaaaatcat
     4441 ctaaagtaaa atcaatccgt gtaaagttcc cctgataatc taatacctta cgaaaaaact
     4501 gttgccaatt tgtttttcgt gtttttagcc atcttgctaa gtgtttacag ccttgacctg
     4561 aaaactccat cacagttcct ttaaccgcat cgtcaatgga ataccgaatc gtgattactt
     4621 gattccacac gtattggcca atatagccct ttggcgcata atccagttcc tcaaaacgtt
     4681 caatgggcat ttcaataatc tcttcaatta gctttaaatg ttgattcgag aaaaagtgaa
     4741 tggttagata atcaatcaaa acacggttaa ctggaacgac ctcttcttgc aaactatcca
     4801 acacaagatt caatttttct tcacttaatt gtctcgttcc tttttctact ttcgataata
     4861 actatctcga aatccccact ttttctgcta aatatcgttg tgtccacccc ctttcttctc
     4921 gagaaactcg aatggcttca ccgagatcat gttgattaac ttggttcata gacaaacctc
     4981 cttctgctat ttacttgtca aagaacctat tgaacttatt ttaagtacat ttttattgta
     5041 cgcctgtatt tattttaagt caatatgttt tgactttttt taagtacaca cgtatactaa
     5101 atttaagaac ttatcctgag gaggagtttt catggagata gacaagcaag cagtcggcaa
     5161 tcgaattcgg cagattcgcc aagaattaaa gttgagtatg gagaaatttg gcaaactaat
     5221 tggtgattta ccgcgaagta cagtcaataa ctgggaacgt gggatcaacc ttccaaaaac
     5281 cgaaaccctt caccaaatcg cagagatagg tcatgtcacc aatgaatatc ttttgtatgg
     5341 tgatcaagag aatcaataca ttttagaaat gctccaaaaa aaggcaggta agcttgatcc
     5401 taagattgaa ggtctcatag tagacgaaat caaacacgct gaccttgtta gtgaaaaaga
     5461 aatggatcga atgattgaat tttttattac aaatctcatt ccaccaactg aacaagacca
     5521 gtttactttc caatgtatcg atgaaaaaaa gcagctttat cttggttcaa ctaattttgg
     5581 taaggaagcc cagctctatt tgcaacatga taatcaaaat catattctgc acatgatgcc
     5641 ctttaccttc tccaacttta gtgtggatcg catactcgtc tatttagcaa atcaaaaatc
     5701 ctattcctat tttgggaaac atttacccaa ggaactaggt gagaaagcca tccttctata
     5761 ctcaattaat caattgacca gcgatgtgcg aattgccccg ttggtctatt cagaagaaac
     5821 cgcttcttat cagtacacag aggacaatca atatctacta gaacagcaat atctttatct
     5881 accattcgtg atggaagtcg agaaagaacg cctgttaaat gcagcgtatc catcatcaaa
     5941 atgaggtgac aaaattgata agcacgtgac aaagaaaata ctgctaggac actccccaat
     6001 gggtagttgt cacagtttcc tgttctttgt tagccccctg ttagaaccgg gggctttatt
     6061 cctgcagtcc ggctacgcct tcctgcaata gacaaaactc cagatcgggt aattcgcttg
     6121 tggcgaaacc cgacctggag tttgtctctg tattttgaac cctaaaaatt aatcaaacag
     6181 actgatattc tcataatcag cgcgaaataa gccattaagt acagttttcc tacctatttt
     6241 tgataacccg ctggttagtt aatattcctt ttccgagaga gataaatgat tggttaaatc
     6301 tatatacatc tcaaccttta aaaatgtttt cgaaatactt catcagtaca tgtcatacaa
     6361 attaccagtg cattctcaaa ttctagttct ttaattgatt tcagttgagg agcagttact
     6421 tttggcggaa atttccattt ttgtccaaac ctcttccccc gatgaaattt ctttgttgca
     6481 attattgcaa tgaaaaattt ttgtttcaaa aatatacata attacttcct ccaataaaaa
     6541 ctatctacct ctcaaattat ttttctctaa taagaaaaac agaaaaggta ataagataca
     6601 acagtgatga ttcctaataa agaaaagact acaataatat ttttctaact tatcgccttc
     6661 aaagaaatag tttcttattt ttcactaaaa taaaaaattt attgcaaaaa aaatagaagt
     6721 gacaaaatta tcaatcattt caaggtaata taactacctg agtttattat cgattaaaat
     6781 gctaactaca tttgcaagag aagcgagagt taaaggtaaa tatagaattt ctactttttt
     6841 agcaatagaa ataggaataa aatatttaaa atgtatagaa actttctttt ttttcttgct
     6901 atctttttat aatcacaact ctctataata gaattacgat ttattttata cggctgaaaa
     6961 aatctatcac caaaaaaatt caaacattaa gccaaggatt atgaagtcaa catttcgaaa
     7021 aatgaacata cattggtaag caactataac tattaccaca gacataaagt aacacaatat
     7081 attactattt aagtgtacgc caccagtgaa tatcctcaag gtatacagcg cacaacaaaa
     7141 agaaaaaagg aaacgcagaa gcatttcctt tcagtgattt aatgaaaaca acacgatttg
     7201 acttagagcc tttttatttg aattcatttt cgctttatcc aacttcattt gatcatttga
     7261 ttactcggtt aaatactttt gacatgagta tcaatgaaac attcattaat tatggttgct
     7321 tatttcttac cgcttttctg gccaatgcta atccgccgat tattccggca ttatcaccta
     7381 attcgggcgt aataatgtag ctatcaattg gtggtatttc aacatatcca tttataagct
     7441 caacaaattt atcctgaact tttttcttca tgtgttcttg tttcattaca ccaccgccaa
     7501 aaataattct atctggcgaa agcatcagtg ttgtattgta tgcacattgg gcaaggtaaa
     7561 aggcttcaat ctgccaaaac gaatcgtcag ccaataaatt ctggcctttt acacccaatc
     7621 gtttttcaat cgctggtcct gctgccatcc cctctaaaca atcttggtgg aagggacagt
     7681 ttcctgaaaa attgtccttt ggatgtcgct tgatcaacat atgccccatt tccggatgac
     7741 tgaacccttc cacgaaagtc ccattgaaca aggcaccacc tccgatacct gttcccacag
     7801 tgaagtatgc aacacctgct aaccctttgc cagaaccagc aacatattca ccatagcaag
     7861 ccgcattgac atctgttgtc cattcaatcg gaatattgaa atattgcttt agcgttccta
     7921 caaaattgaa attttgccaa gcaagttttg gtgttgatgt gatatgaccg aaactcgttg
     7981 atttgcattg aatatcaatt ggaccaaagc agccgacccc gatgcctgcc aattgttcct
     8041 taaaaggttt aaaaaaatca atgacctgct tcattgtttc aactggagtt gttgtgggaa
     8101 aactgactct ttccaaaatc gttaattcct cagtaccgac tgcacagaca aatttagtcc
     8161 ctccagcttc aattgcccca tatatcatca taggttcctc ccttcgaata tgtgaaaaac
     8221 acttcattaa cgcggcaagc gttctcgatc agtgaaatga cgtttagtat ttcctgaagc
     8281 ttctgttgaa taccaatagg cgacactagc aacatcgtct tgccgctcaa ataagcgaac
     8341 atcatcgttg ccgatttgtt gtaaagtgac cgataaatct tcggtaaaac agatggggtc
     8401 ttgaagatgc caacgataaa gaccatgtcg tggcattgcg tcgtcaccaa aggcatgaac
     8461 ggcattcaat tttcccgttt caaaacgatc tcttgtggca tctctatttg attggtaagg
     8521 ataccctaaa aaggctgttg aatagttttt cgcatgtgga cgtccgaact catcgtactc
     8581 atgaaaggcc cacgccccgc caaaataatc ttctgaacct gttgaggtta cggtcggata
     8641 ctcactatcc ccatcaatgt agaatttaaa ctcgccttcg ccccaccaat aacgttctag
     8701 gcaggtaagc gcaaggtaag tacccacgta atagccttga ccctttaatc gatcaattaa
     8761 cttataatcc tcctgtaatt tggtaatgcg ttcccgatgc caatttgcgt gaaaatatag
     8821 gctattttct tccaattcgt ccaccaaagc gtaatttatc gtataaaaaa atgaggacat
     8881 atccttcgga tgtaaattct cgatcgtaat tttagcggat gtttggaaag gcatttcgaa
     8941 ataggaatta aagccccccg taggattaac cactataggc aacgagttca cctcgcaacg
     9001 ctctccaaac ccattacaaa agaaatcccc taaaggactt tcaacagccg ggctatccga
     9061 cccatcccaa taaattctta agattaaatc acgtaaaaca aaactgccaa attctgttcg
     9121 atcacgaatc gtcatccaca tatgacgaat tattcccgtt ccagtaatat ccgcaatcac
     9181 agtttcttca ccagaagtca gcggaattgc gccacgacct ttgcggcttg gtcctagctc
     9241 gcttggcaac atcgcagctt tacctttctc gcctgttgga ttttcgggag tgattgctcg
     9301 actctggatt tttttaaatt gggtaatatt ttttagtata ctcatctttt tctcctttga
     9361 atgtaaatcg tttttccctt ttctacgtga agaatttttt tcgtatcact tattttcaat
     9421 ggcttttctg acaaatttga aatactcaac tcggattgcg tacattcaat cgaaatgaag
     9481 gcttgaccga acttcaaatt tttccaagaa aacgttaaat tatcaacagg atcaatttgc
     9541 aatactcctt ttttgaattt caatccgaaa tattgactga tcattatact gacaaaaagg
     9601 cccgatgccc agccgcattt gccgcagcca aagtctcgca caacttctcc ttgtttagcc
     9661 tctaaacgat acggccacca ccaccatgaa ccgtctaaat ctgccaaaca aatcagctcc
     9721 tctaatcggg ttacgaaggc ttgatggttg tgcatgtcac tcattaaaac agtgataaag
     9781 ccaggaaaag tggcgccgga ttctaatccc caagtgatgc ctttgatttc ctcgctataa
     9841 gttggattga aagaactagc agaaaaggtc atggtgttct gatataaagg atctttatta
     9901 tctaaaaatt gataaaaagg catcaacgta gtgtctgatt cttctccatc atgcatcaat
     9961 aaattgattt tcccatccac aatcacatca cttaaaaaga ttaacccttg ctcaagaatc
    10021 ggtttttgat agttcttcac tgaataggtt gttttctcct catcaccgat cccctccaaa
    10081 aattgctccc caaaagtacc atctatggtc atttgtttac aaattgattc ctttagttta
    10141 caggcgatgt ctttgtatcg ctcgctaaga ctcagttgtt ctagggcttc aaaaatttct
    10201 gcaagtccac tacaggcctt ccaaagacaa agattgctgc cggtatgata ctttccaagt
    10261 gcaaaggcgt ctgataacca aacagatgga aaaagcattg gttcccctga ccgacgttga
    10321 gctaatatgt cctcaataat tcttgaagca ttcagtagaa cctgcggaca ccgctcaaag
    10381 aattttgtat ccccagtatg ttcaaaataa agactagcca gtaacgcact ggataacgaa
    10441 ttactcagag aatgattgat acctcctgta aattttgaac caggaaactt aacgccatat
    10501 tgatcaaacc atagaaccgt tttttgacat aactccggtt caaacatggt gaatggcaat
    10561 gatgcgtaat acatatcctt attccaaatt cgattagtag caggatagct gccccaattg
    10621 ctgccgacga cctgtccctg tcgattcata ccgaaactag aaaagctttg ataaagtgca
    10681 cgacgataga gatggacaac tctatcgtct gacattgaca gctgcccaaa tagctgagca
    10741 aaatagttca ttgtttcctt cagccatttt tcgatatcag attcctgaaa agtcattact
    10801 tcttcaaaag catttgggtc cacaaaagca atggcgaagc ttgccacttc ctgttgtgcg
    10861 atcgtgtcct tatttccttt ttgagaaatc aacacatttt gctgatccga atacttctct
    10921 tggtacaaag gcacatcttt cactgaaact tgaaggcttt cgtgtgtttc attcacaatg
    10981 taaacctgtt gaacaagcat acttaaacgc ttattagcca gtattggagc aaaggatact
    11041 acaatgacct taaacgtcga ataatgatga atatatctag gcaaacagtc ttgaatcaca
    11101 tcgacttcaa tacgatgatc cgattctgac aaatggtaga caatcccgtt tacttcaacc
    11161 tttaaggata acgaattggt ttgagaaagc tgtttattga cccaaacacc tggtttttcc
    11221 tcagttagta aattttctcg ataaaaggtc aacgtttgaa tcgtcccgca aacatcaagg
    11281 tttcctaatg tcttttgatt acttacatca aaggtcaatc cctttacatc aggaatattc
    11341 cgatagtagc tgtattcgtt tgaagtagtc acatttccgt cgtttaactc agcattaaat
    11401 aatgggtgtt tgggtgaata aattacttca ttaatagtca tcttttccct ccttgctaaa
    11461 aaaactgcag cctagtagct gcagcttcct actatgcgat tccaagtaat gacaataaaa
    11521 ttcccaagac gaccattcca aaaataattt tgatgacgcc gactttttta tctagtaatt
    11581 tgaaacagcc caatgttacc aataacggta caattccttt aaaaatacta tcgaggattt
    11641 cttggacatt cattagttct tcgcccttca ttgaaaagct caaaacggta ttgaatttga
    11701 ccatactgat cgtcattgcg cctaccatga tcagacccaa gatactagca gcttttgtca
    11761 gaatttcaat taacccgttc gcatacagct tttcaatata tttagagcct aatgaatagc
    11821 ctaaaacgcc gccatagtat cgcatcaaat aattaggtat attgaacata actaaaaaga
    11881 taattggtgc caaaatattt ccggcattgg ctaagttgat cgctagtccc gcggtaacga
    11941 cacgccaaac tccccagaac aatgaatcgc caattccagc caatggtccc atcaaactcg
    12001 ttttgatcgc gttgatactt tccacgtcaa aaccagcttt ttcagaattt tccttctcca
    12061 tcgatgccgc aatccccatg acaaaggacg cgcaaggaat ggtcgtcgaa aaatactgtg
    12121 tatgacgttc cagcgccgca gctcgatctt cttcactttt gtagaaatga ttaatgaagg
    12181 gcatcataga ataggcgaaa ccaccgccgc ccatcgtcac cggattcacc gaagcataca
    12241 tggtcatcga gcgccaaaac atcttccgaa ccaatttttt ctcatcttta gaaattccat
    12301 cagctaattt cattgaaaga aatcctcctc ttcttggtca agcgttgcat ttacagcagc
    12361 atcgctttga actgcatgaa cagatatatt ttttagttgt agatctcttt gggctataac
    12421 aattgcaata atcgttccaa ctgcggcaat tgcaatcaat ggtaactcga gatacgccat
    12481 aacaacggcc ccaaagaaaa accacacagc aatattttta ctccaaagca tccgtaacag
    12541 catcgccatc ccaactgccg gcagcagatt tccagcgact gttaatccgt tcatgatgac
    12601 ctctggaata ttatccaaga cgcttttgac aacatctgct ccaaataaaa cggcaaagaa
    12661 tggaataaga gcataaagcg catagtggac aaaccacata acgaagtgca gattgatgat
    12721 tcctttttga tcaccagatt ttgcaaattt gaaaaattta gcagccatcg gtccacatac
    12781 aaaagaaaaa atcatattca ttaactgtaa tcctaatact gctagtggaa agacaatggg
    12841 aataatcgca tccacgtttc ctcccatttt gattgcgaac gctgtagcca acccagcagc
    12901 caaagaaggc tccgccgtac tagagattcc gatattgacg acacccataa aaatggcttc
    12961 tagtgacgcc ccgacaatca accccgtctg caaatccccc atcaacgctc ctgctaacgg
    13021 agcaacaaca atcggacgac tcagcatgga catcccgaac atttcatgtc cagcaactcc
    13081 aataaaaacg gccaaagcga ctacaaatgc atcatacata atttttctcc ttcctttttc
    13141 taaaaatcac tcaaaataga gatagctgaa cgtttttcca tcgccggtgt aggctgaaaa
    13201 acggtatctg gataaagttc aactaattct tttaagtctt gaatttctga cgtcgttaac
    13261 atcacttcct ttgataaggt tttcttatct tccgatggcg gtgtcatttt cccagcattc
    13321 cccacgttca ttaattcgat ttccgttggg aaagctttcg caacttttac cgcatctttg
    13381 acattaggga ctaaaaccat caagcgcatg tccttcgccc gcggatcttt taacaaatga
    13441 atcgcgtcat caactgtttt aataatgact ttgacattcg atggtgcagc catcttcaat
    13501 gtcatctttt gaatatcgtt ggtagccgcc tcatcgcttg ctactactaa cccggttaaa
    13561 tttagactct ttgtccaagt catcgctact tgtccatgaa ttaatcgttc atcaattcgc
    13621 actgctttaa tcatttttct tcctcctaaa aaaaatcttc ctcttcattt actacatgta
    13681 cctcatcaag aatggtcatc tttaattcct gttggcattt atttaccagt tcctgaatat
    13741 cctcctttgt taattccttg gttgccaata ctatttcgag cagaattggc agattaaagc
    13801 cagacaaaat agttacagca atctctttct ccaaaaaggt tttggtaatc ttctgattga
    13861 cacttccgcc aaataaatcg gtaaaaacaa aaatctgatc ctgctcgttc acctggttta
    13921 caaatacatt caactcctgt tcaaaatcac actcatccac ataagcatta atcaccgtaa
    13981 tctcttgaac cttccccgtc agtaattgaa tactgctaag aaagcctgaa gctaagtgac
    14041 cgtgagtcgc tattagaatt ttcttcatat ggttaattcc tttctttctg ttcactttta
    14101 tataagcaat tcctgtgcca acttttaaaa acattggttt aatcacgtta attcacatta
    14161 aaaaaagtgt ctaacctaaa aaaaacagat tagacacttt tttagacact ttatttttga
    14221 atatacggtc ctaataattc atagagcagc gaaagctcat aagcattgac tttaaaatta
    14281 tatttcatct ccattgattg aaaaatactt ctagaaacat aataaaattc atcttcatct
    14341 ggtttcaaat cataattcgg ttcttcagat ttttctgtcc gagccaagaa taaacgttcc
    14401 atcatcaatg ccgtatgcat atagagattt agttttacac ggccatttaa agtgaaatga
    14461 tagtaatttt catatttaga aatgactgtt tccacttcac tcatcacgat cgttgggttc
    14521 agaaagttca aacggtccgc aattccttcc aacgaaaaga attttactag ctcctgaatc
    14581 aagcggttaa attctgccgg cttcatttca ggactcaaaa tatgctccaa attggctgct
    14641 ccatcaccgt ctaagatgtc ataaacatta atattaggaa ttgaaaagga acgtggaaga
    14701 tccgaagtcg tgatgaccaa ttttgtcttg tcaaaataag tttcatcatt ttggtcgatt
    14761 aattcacgta gttctctgta gtccttcgtg aaaacttcga tggattcatc cgataaatga
    14821 tgacgaaaaa catctttcaa tttgtccgaa atccccaaac ccgacataca ggaaatgata
    14881 atgttgctac tttgagaaaa gccttcaaag tattgaacat tgattgaata cttgtctgct
    14941 gcatcctccg caatctgttt aaatggcgca ttcatcgtca tcttcaagcc aatatcaagt
    15001 gcaatggaag tcgtcaaatt attcagaaga agtaactccc cttttaaatc gttcttgatc
    15061 tgtgtgtaaa tttgatttaa agagcccata tctacgatca gcactagact atctgtattc
    15121 acttgccgtt tcacgaaatt ccttgtcgat tcgacaatct ctgacacatt actctctact
    15181 ggcatatcca acgcttcaaa aacataattg ccgcataatt gattcactac tgcttgaatg
    15241 ctgctagccg tactatctcc gtgagcaagc aacaggccct tcagctcgat ggattcatct
    15301 acataatcag ataaagtcac gacaataagc agtcttagaa agttctcgtc cttttctgag
    15361 agcggtggta aatgctccaa gaactgatta cataagtaag tcgtccgagg tagatttgca
    15421 gctaatgtac gatttatccc ggttaagtct gtcttatagc ttggggaaat gacataggat
    15481 ctgctaataa tttctgcaac aggtccactc gtcgtcaatc cgtacgtttt tcctaaaacg
    15541 gatacccaga cctttctaaa catctgaatc atcaattttc tactcattga taaaaaagaa
    15601 tccttatcaa tgtgatgcac caaatgctgt acttcattct ttatcgaaga aaaattttca
    15661 ttgaaattac cttcatttat cagctgagta attttttcca aaatcgaatc ataatcaaac
    15721 ggtttgattc gatccgtttt tatcttttga tttttcttta tcaataaact agcaatcggc
    15781 aagctttcta cttcggattc cagcatattt aactgaatca agatctcatt tttcccaatc
    15841 gttaatggtt cttcttgtgt tcgactatac acatccgcac aactgatttt aatgatattc
    15901 ttcagcttac caatattccc actaaaggga tgagataaca ttaaagacaa ggcttctctt
    15961 gaaacaataa tatctttttg taaaacatcc gcttcatttt gaaaaaataa ttgaatcagc
    16021 tctaatcgtt ctcgaatggg gcgatcttca aaagttggca acataacact aatttgaata
    16081 cgccgatcaa aggtgtctaa taaataattt tcaccttttt ccgtcgtggc gaaaataaaa
    16141 cgaaccttag cagaatgcca atttacattt tcaccgactg gacgatagtt tccagtatca
    16201 ataaatagaa agagcttttc ttgattttct ttcgataggc gatggacctc atcgagaaaa
    16261 agatagccgt tgttggccgt tgccaataaa ccatcggtat ccttttcagc ccccgtaaag
    16321 gcccccttct tgtatccaaa cagtgttgcc gaaagcagtt cgggattgtc cgcataatcg
    16381 gcacagttta agatagcaaa tggtgcatct ttttcaataa tttgctcatg gatagcgtat
    16441 tcaaaaattt ttgtggctaa aaaacttttt ccaacacccg tggctccatt tattaataca
    16501 ctgagtccgt taggcggata tttgacagcg gctatacatt tttgaatgac ctctctcaga
    16561 cttccgtcat gaccaactac agaatgaaag gcttcgttta tttgctccgt attatctaca
    16621 accgcatatt catctaaagg cttccacaaa acaggctttc ccggtaattt ctcgaccttt
    16681 ttatcttcca ctaatctcgt caaataatgg ctggcattct gacgagagat acctagattc
    16741 ttcgaaattt tctcggcagt gacagaagac atattccctg ttagtcgtat cagctcatca
    16801 aaaactcgat ctttagcgct ctttttcatt ttttcctcca gtttaatgtg tctaaaagca
    16861 taataaacta tcggctgcaa tatgtctatt ctatatttgt attccaattt ttactttgaa
    16921 acacaaatag tcgaatattt gcctcagata tctgacaaaa taatttatct accaatttag
    16981 tttttatcta atatgatttt tatgtttttt catagctaca aatattgaac tggattcata
    17041 tattagtttt attaatagat tacagaaggg ttaagtatat ttgcatagtt tccaattact
    17101 ttatccttct gtaacttttt caatcttaga tttactagcc cgtctcgggc cctattttac
    17161 aatggttttg tccacttttc tctggtagaa aaacgtggta gaaaaaataa aataacacaa
    17221 aaaaagcggc gtttcatccg cttttggtag aagattggaa aactcagata gaaaaaggac
    17281 gatttttagc tctttagaac gttgataagt ccccattctt actgagtttt gccattatct
    17341 cctatacatc ttgaattcta agaataggtc attatagatg cctaggtatt tcgatcctag
    17401 atctttgtag acttcaagat gggagatcgt gtcatcagat ggatagaatt gttcgtccga
    17461 cgaaatgtct tttggcaata acgcttttgc ttcttcattt ggtgtagaat aaccaatata
    17521 ctctgcattt tgtgccgcat tttccggttc tagcataaag ttgatgaaat cataggcacc
    17581 ttctttattt ttcacggttt ttggcataac gatattatca aaccaaagat tggatccttc
    17641 tggtgggatc acataatgta aatgttcatt ttcccacatc atatcggcag cttcgccaga
    17701 aaatgtcact gccacggagg cttcttcatt gatcatatac attttgatct catctgccac
    17761 gattgctttg acatttggtg ttaaatgatt caatttattt gctgcttctg tcagctgtgc
    17821 catattctta ctattcaaag aatagcctaa actattcaaa gaaagcccca taacttctcg
    17881 tgcaccgtca atcagcatca aactgtcttt taattccggc ttccacaaat catcccaatg
    17941 cttaatttga tttgcatcaa agaatttatc gttatatacg atccctaaag ttccccaaaa
    18001 atatggaatc gaatactgat tatctggatc aaaatccaag tctaaaaatc gtggatcaat
    18061 attatttaat cctttgatct tcgaatgatc taatggaagt actagttttt ctttgatcat
    18121 tttttggatc atatattcac ttggtatagc gatgtcgtag tttgtcccac cttgctggat
    18181 ttttgtgaac atcgcttcat tagaatcaaa tgtttcataa ttcactttgt atccatattc
    18241 tttttcaaat ttcgtgatca aactaggatc gatataatct ccccagttat agatggtaag
    18301 tacctttgct ccactcatgc cacttgtttt ttcaagttga cgaacaccaa gcagcagcac
    18361 cgcaataatg atgagaatac ctaaaaacag agattgtaat tttttcatcg cagccgtgcc
    18421 accccctcgc gtactcttct gtttttcttc agccgttttg gacggttttc tttactaata
    18481 aagtagtatc caatgaccaa tatcatggag aacaagaaaa ctaacgcact tagcgcattg
    18541 atttctaaac tgattccttg tcttgcacga gaatagatct ctactgagag cgtcgtaaag
    18601 ccatttcctg tgacgaaaaa tgtaaccgca aaatcatcaa gagaataggt aaatgccata
    18661 aaatatccag ctatgattcc tggagaaaga taaggcaaaa tgatattttt gactacttgg
    18721 aaattattag caccaaggtc tctagccgca tcgaccattg aatcgttcat ttcctgcaat
    18781 tttggcaaga ccatcaagac gacgattgga atgctgaaag caatatggga aagcaataca
    18841 ctctgaaaac ctaatccgaa tcctagtagt gtaaagaaaa tcaagaaact agcaccgata
    18901 ataacatcag gagagactaa taagatgtta ttcatgctca acaacgctgt ccgtgcacgt
    18961 cgttttttcg tgtaatagat tcccatagcc ccaaatgtcc cgatgatcgt ggcgatcaat
    19021 gcagataaga aagccagcat gaacgtattc aatacgataa tgatcaaacg tgtatcttca
    19081 aaaacagctt cataattttc ccaagtaaat cctgtaaagc tgttcatcgt tcctccttca
    19141 ttgaaggaat aaaaaatcag atagaagatc ggtgcatata agaataaaaa gacgatccct
    19201 aaataaagat acgaccattt aaattttttc atttatgagc gacctccttt tttcttctcg
    19261 cctgtcagga gcatcacgat gaacatagca atgattaaaa tcacaccgat tgtagaaccc
    19321 atcccccagt tttgtgtaac caagaaatgc tgttcgatag ccgttcctaa agtgatcacc
    19381 cgatttccgc caatcagacg agtcagcatg aataaagaaa gagaaggaat aaatactgct
    19441 tggacaccac ttttcacacc atttaatgat aacggaaaaa tcactcgtcg gaaggtctca
    19501 aagctattcg cgcctaaatc tctactagca ctgatcaaag aaggattcat ctcttccaat
    19561 gcattgaaaa ttggcataat cataaatgga atctcgatat acgttgccac gaacagaaaa
    19621 ctgaagtctg tgaataatat ctgtttcggc ccgatcccga taaaatcaaa gaaatgattc
    19681 acgctgccgt gcacactgaa aatcccaata aatgcgtaag ctttaagcag cagattcacc
    19741 catgtaggca aaataatcag catcagccat aattgcttgt gcttcagttt tgttaaaaaa
    19801 taagcagtcg ggtaactgat gatcagcgtg aaaaacgtga tcaaaaatgc ataccataca
    19861 gaattgatcg tcatagaaag cgatgtcccc gacgtaaaat aagatagata attattcagc
    19921 gtgaattgcc cattcatatc aaaaaaagat tgataaatga tcattaatac aggcgcgatc
    19981 acgaataaac cgagccacaa aatataaggg acggaataga tcctgcgcat tgttttcatt
    20041 cttgtccccc ctattcttcg tagctgtcaa gacgtgcatc gaattcttct tcagactcgt
    20101 tgaaacgcat gacatggata tcttctggct caaaggccaa tcctactttg cttccttctt
    20161 tagctttttt cgttgaatgg accatccatt cattttgctg ttcatcataa cagatgattt
    20221 cataatggac accacgaaac agctgagtat cgaccgttac gactagtttt cctttatctg
    20281 gtgtcgtgat cgtcaaatcc tctgggcgta aaacaacttc aactggttca tttagacgca
    20341 tcccgccatc gacacattca aattgcttac caacaaactc aactagatta tcttcgatca
    20401 ttacaccgtc cacgatattg ctctccccaa caaaatcagc aacgaaatga ttgattggct
    20461 catcataaat atctacgggt gtaccacttt ggacgatttt ccctttattc atgacaaaaa
    20521 tctcatcact cattgccaac gcttcttctt ggtcatgagt aacaaaaata aacgtgattc
    20581 ctaatcgttg ttgcagatcc cgcagttcat actgcatatc tgtacgtagt ttcaaatcaa
    20641 gcgccgataa cggttcatct aatagcaata ctttcggttc atttacaatt gctcgtgcaa
    20701 tcgctacacg ctgtctttga ccaccagaca tttcactaat ctcccgtttt tcgtatccag
    20761 gaagctggac catacgcaaa gcatctttta ccttcttttc gatatctgat ttggacattt
    20821 tcttgatctt caatccaaaa gcaacgttat caaaaacatt catatgagga aaaagtgcat
    20881 aatcttggaa gactgtattt acttgtcgct tattagctgg caaatcattc aaccgtttcc
    20941 cttcaaaata gatgtcccct tctgtagctt cggtgaatcc agctataata cgtaggatcg
    21001 ttgttttacc acagccggaa ggaccaagca gtgtataaaa ttttccttgt tcgatctcaa
    21061 aacttacttt ttttaatact gtttcatcat catagcgttt cactacttga tcaaatgaaa
    21121 tgattggttt ccccacgttt ttacccccta tattacaaat atgattgcgt tgcaacaatc
    21181 aatacttttg ttcgtttttt gagatgattc cttaattgat gttgttttgt cgcttgataa
    21241 tagatcgact gtcctgcttt tgccacatag accgtctctc ctaagcttaa ctctaattcc
    21301 ccttctaata caaaaataaa cgtttcagat aatgaaggtt caaacgtctt atattctcct
    21361 gcaccttcaa aagtcagcaa gacaggctcc atttcttttt cattcgaatc agccacgagc
    21421 cattccaatt catacccgtt ttcttcatcg aaataaaccg tatgatcttc ttttgaataa
    21481 accacttgca gattcgctgc ttcttgatga aaaaattctt ctggagtcac acctaagact
    21541 tcaagaatag aaaagaatgt ttccattgat ggtgaactta aatctcgttc caactgggaa
    21601 atataccctt ttgacaaatc tgtgcgttcg cctagttctt cttgtgtcaa attcttttgg
    21661 atgcgcaaat ttcttaactt ctcaccaatt tccataattt cctccgaatc gaagttttct
    21721 aatagtaaac ttcctgttta ctaccactcg tattagtata cgaaatttat tgaaaaaggc
    21781 aaccctttgt aaaatttttt ttgctgaata tttctttatc ttttggaata aattctagtt
    21841 gtttgattct ttatttttca cctaattttt gtctaaattt acggaagaac aagaataaaa
    21901 gagtaggctt tatggtatga taaaagaaaa ttttaaaagg agtgtctcac gaatgaacgc
    21961 ttttcgatct tttcaggtaa taaaggaacc tgttttccat acagcaatca gtgatctgcc
    22021 atttactgag ttggctgaaa atgaagtctt ggtaaaaatt gcctattctg atgtcaatta
    22081 taaagatgca ttggcaatga gcgagtctgg tcaggtgata cgaacatatc cgatgactcc
    22141 agggattgat ttatccggaa ctgtcgtcca aagtaacaat ccacgttttt caaaagaaga
    22201 tcttgtactt gctactggtt ttgggcttgg cgtcacccat ccaggcggtt atagccaata
    22261 tcaaaaagta ccaggagact ggttagttcc tctaccaaaa aatatgacgc tgcgtcaagc
    22321 gatgatcctt ggtacagcag ggtttactgc tatgttgtgt gtgaacgctt taatccgtca
    22381 aggtatgacc tccgataaaa aagttgtcgt tactggtgct tctggcggtg taggcagtac
    22441 agcgatagcc ctgttacata aactaggatt ccagtcaatc attgcctttt ccagaaaaga
    22501 agagtctgtc acatggctaa aaagtctagg tgctttgcaa gtcgtacgac ctgatgaatt
    22561 tctgccagag acaacaaaag ctttaggaaa acagcaaatc gactatgtca tcgacacagt
    22621 aggtggcgag cagctaagca gtcttcttcc attgatctct tataacggtg cagtagcttt
    22681 atgtggcaat gctgggggaa tcaaactaaa cgcgactgtc ttgcctttta ttctgcgaaa
    22741 catccagttg attggaattg attctgtcaa tgtaccaata gatcaacgtc tttctttatg
    22801 gcaacagatg gcggatttgc agattgcaga tgaactggtc gtccaagaga ttactctgga
    22861 tcaattgcct gaaacagcat ctaaactact tgctggaaca caccaaggaa gaacactagt
    22921 aaatgtaggt gaccataaat gaagattcta atcacagctg gaggaacgac tgaaaaaatc
    22981 gatcaagtac gtgctattac aaatcattcg acaggacgat tagggcaagc attagctgat
    23041 tatttagctg ccaatccgga taccacaatc gattacgtga ctacgaaaca agcactgaaa
    23101 ccgaaaagac actccaatat aacgatttat acgatcgaat ctgcactgga cttattttta
    23161 caattagaag aactaacgaa aaaagaacac tacgatgcga ttatccacag tatggcagtc
    23221 agtgatttta ctcctgcttt tagtttttca gaagaacagc tggcaaaaaa cctacccact
    23281 tcttcaacgc aagaagaact ggacaattgg tttgcggaaa atgaacagac agataccact
    23341 gtttcaaaga tctcttctaa caccgagcat cttgtgctcg ttttgaagaa aacaccaaaa
    23401 atcatttctt atctacgtga atggcagcca aaagcaaaaa tcattggttt caaactatta
    23461 gtagatgtac caaaggaatc tcttctggca gtcgcaaaaa atagtctgat aaataacaaa
    23521 actgatttta ttttcgcaaa tgatttgacg gaaatccatg gcgagacaca ccacggctat
    23581 ctcttatcta aagatggaac agtggaagaa gctcaaagta aatctgagat tgctgcattg
    23641 attactgaga aaattagact ggaggaatca aaatgaaaaa gatcttacta ggcgttactg
    23701 gaagtatttc tgcttacaaa agcgctgatc ttacaagtca attcgtcaaa ttaggtgccc
    23761 aggtagatgt gattatgtct aaaagcagca cacattttat cacgccatta accttgcaat
    23821 ctctgtcgaa gcgcgcagtc catacagacg tcatgcaaga atcaaatccg caggtaatca
    23881 atcatatcga actagcaaaa caagctgact tgtttctcat cgcgcctgct acagcaaaca
    23941 ttatcggcaa gctagcaaac ggcattgcag acgatcttct ttcaacagtc gcaatggcgc
    24001 ttccagtggg aacaccaaaa ttgattgccc ctgccatgaa cacgaatatg tatcaaaacc
    24061 cgatcactca gcgtaatctg gaaacattga gatctgtcgg ctatcaggaa attgaaccaa
    24121 gagaatctct tttagcttgt ggagattttg gaaaaggtgc cttagctgat attcagacga
    24181 tcatcgaaca ggtcatgctg actcttaatg aaagaaatgc ttagaaaaaa ggagtactta
    24241 tgaaaaatac aaaaaacttt acattaactg cgatgttttt agctattttg attttattag
    24301 ctgttacgcc tttaggtttt atccctatcg gtccaatcaa tgcaacaacc atgcatattc
    24361 ctgtaatcat tgcttcgatc gttttaggac caagactagg tgcttttctt ggcggtacat
    24421 ttggactgat cagcatgatc cgtagcacag ttatccaaac acctttgtct tttgtctttt
    24481 ctccgtttat cccagtcatc ggaacagaac atggaagctg gaaagccttg ctgatcgcgt
    24541 ttattcctcg catcttgatt ggggtggttc cttatttcgt ttataaaggt ctgcgcaaac
    24601 taatgaaaca aaaagcagat tccgtttctt tattcttagc tggactttcc ggttcattga
    24661 ccaatacgat tttagtgatg aatatgatct actttttatt ccagcaagat tatgccaaag
    24721 tcatcggaac aaatttaaat gctgtttatt cagctattct agcggttatt tttacaagtg
    24781 gtatacctga aggaatcgtc gcaggtcttg cgactgcagc agtatgcaat gtcttgttaa
    24841 gatacttcaa gcacccttct cttactaact gatagtcatc gtagccgatc tctgattttt
    24901 ttctcttttg gtgttactat tgaatggaaa gatttgacgt cgaaaggatg atccaaatga
    24961 aaatttttgt tgtaggtgca aacggacaaa ttggccgaca cctgataaaa gatttagctc
    25021 caagttccca tgaaattttt gcaggggtga gagatgttgc ttcccaaaca ttagtaaaaa
    25081 aagagaatgt ttcgtatgtc tcttttgatt taacttggtc cgtggaaaaa atgaccgaag
    25141 cattcaaagg catcgatgta ttgatttttg ctgccggctc tcaaggaaag aatcttctgc
    25201 aagtagactt ggatggcgca atcaaaacag tgatcgcagc tgaaaatgcg catgtctctc
    25261 gctatctgat ggtcagtgct gtttatgcag atgaaccagc aaaatggcct gagtccatga
    25321 cagattatta tattactaaa cattatgcag atgaatggct gaaacgaact aacttagatt
    25381 ttgtcattct tcaaccagtc acattgacta acgatgaaga agttacttcc attcaattaa
    25441 ctaagcctaa tgagaaggca tcaaaaacga tcactcgctc tacagttgct gctgtacttg
    25501 ccgctctagt ggaagaaacg gatatttctc gtacgactct agtactttct gaaggtagca
    25561 aagagttgaa tacagcattc caagaatggg caaaggagga atagatccat gcgtgccatt
    25621 tcaatcaagc atcctggttc tgtagatgta ttagaacaaa ttgaagtgcc tgttcctaaa
    25681 ccaaaacaag gcgaattact gatcaaagtc catacagcag ctgtcaatcg aacagatatt
    25741 atgaaaagag aatcagtctc tttgaaacct ccctacccta ttttgggagt cgaagtagct
    25801 ggagaggtag ttgagaataa aagtgatatc tccactttta ctcctgggac aaaagtatac
    25861 ggattagtca atctaggtgg ttatgccgaa tatgctgtga tgcctgccga tcgtgcaatc
    25921 cttctccctg atacgctaga ctatgtttct gctgctggaa tctcagaagt ttttttgact
    25981 gcttatcaaa cactttactg gcttggaaaa ttacaagaag gcgaaactgt cttgatccat
    26041 gcaggagcaa gtggtgtggg aacagcagcg atccaattag ctagacagct ttctcacgcg
    26101 aaaatcatcg ttactgcagg atcagaagaa aaactcgcct tttgtaaaga acttggtgca
    26161 gatgaattga tcaactataa aaaacaagac tttcaagaag aggtacgaaa aatcactgaa
    26221 ggtcggggag tcgatgttat tttggatttc atcggcgctt cttactggga aaagaattta
    26281 gcttctatag ccgttgatgg acgttgggtc ttgattggta tgctaggtgg gaccatcgtg
    26341 cctgagatag accttggtgt attgattggg aaacgtgtcc aactgcttgg tacattattg
    26401 acacctagaa gtgatcagta taaagcagag ctcgcacaaa cttttatgca aaaagctggg
    26461 ccttttctag aaaatggcaa gattcggcca atcattgacc gtacattcca attcagcgca
    26521 gtcaaacaag cgcatgaata tatggaagca aacaaaaaca tcggaaaaat cattttgaag
    26581 ataactgaat aaaatcatgc tgatcaaaaa agaggctggg acagaagcgt ttaactccaa
    26641 gaaataagaa gaaattcacg aaaattgctt ttcaaatttt tgtgaatttc agcttatttc
    26701 cgaaggaatt tcttctgctt ccgccgttta tacgtgttta gagcgtgaga caaaagtgtt
    26761 ctttactttt gtcccacgct ctttttccga ataaacggtg ttcaaaagct tgcatctgcg
    26821 gtaataagtc caaccaagtt aaaaacataa gaagctgttt ttacttggct gttcttatta
    26881 cttgatgcag ggcagctttt tcacaacctc ttcactaaac agtgttcaat cagctgaccc
    26941 tcggtattag ctcaaaacgc tggtttcaca acctcttttt atttacgttc tatttcattc
    27001 attttccgaa gcaaatcgag ctgcttgtat gcccgcttgt cgcccaaaaa taatgatctc
    27061 cgcaactgaa tttccaccga tccggttgtt tccatgtaag ccacctgtga cttcaccagc
    27121 agcatataac cccctaattg gctggttttc tttatctaat acttcagtgt tcgtattgat
    27181 tttcacaccg cccatcgtgt aatggattcc tggtgcgatt ttgatcgcat aataattcgg
    27241 agacgataag tcatgttcca tggctgtggc acggttgaat tgagcatctt ttttctccgc
    27301 aacatccgta ttccatccat caactgtttt tgctagtgtt tcttttggta aatcgatttt
    27361 ttctgctaat tcttccattg tctttccagt tgtgacatat cctttttggt cataaaattc
    27421 aatagctgtg gcacgatcac gcacgccttg gtcaaaaatc aaataagctg atttttcagg
    27481 caatgctgta attgctgcag atactttatc ccttgtatcc atttcattga caaatctttt
    27541 cccctcttga tcgaccaaga ttgctccttc tccgcgaaca acctcaccaa tcaagacccc
    27601 ctcatcctgc tgcacagttg gatgaatttg tattttatcc atatcaacgg tttgtccacc
    27661 taatttttca atcatggtga taccatctcc agttgatcct tcttgatttg tcgtaatata
    27721 atcagctaaa tcgggacgat atttttcaat aaattctttg ctggcaccaa aaccgcctgt
    27781 ggtaactacg attgcttttc cggtgacctc ttttggttct tctccttgaa catgtacagt
    27841 cacttcattg accgtttccc catttttctt aatgtctgtc acatctgcgt tgacaaaaat
    27901 agggatttcc cgctcatgga cgttattcaa taacccctcc actaagtatc caccaatagc
    27961 cgagccatca gacggacgat gtgtcctctt ttcactcatc cctccagtga tcgttaagtt
    28021 gtccagtttg ataccgtttt gatctagcca atcgaccgca tcagcagagt gatcgacaaa
    28081 gtatcgaagc atttctttat cattcgttcc tccaccacct tttagcgttt cttcatagaa
    28141 ggcatcattc gagtctttga ttccttcttc tttttgaaat tttgtttctg aagcattcat
    28201 accgcttgat gatttagatg tgtttcctcc ggcaacaggc atcttttcca aaattactgg
    28261 attcaaccca gcatcttttg cttcgatagc tgctgccatc cctgcaccac cagctccaat
    28321 aatcacgaca tcataagatt ctttcatttc ttttggatct gtatatactt gttcagaagc
    28381 gcctgatgat acttcggcag attccttcgt actagaactt gtctgtgctg tatttttctg
    28441 atctgcgccg catgcgctca tagcaagaag tgcaacggct gttaataaac cagcaactaa
    28501 ttttttcatt tgtatccccc ttttctcctt atactatatt aagtgatttt tttcacaata
    28561 tcaactctgt ttttctttaa gtcatatagc tttggtaaac acacgcttct tagtataatt
    28621 aaggatatac atgaaggagt tattttatga atcatttgaa aacctttttt acgaacagta
    28681 caaaaactgc aggtagaatc acaaacggaa tctatatttt attacgtatc atcgtcgtta
    28741 ttatgctagt ggatcaggtc tggaaccaac actggggaaa tacaatgctt ttattactga
    28801 cattaatttt atttgaaatc ccttattttc tggaaaagat attaaagata cagattccaa
    28861 atatgctaga aatcattttg ttatctttta tttttagttc aacagtttta ggagagttaa
    28921 gtgattttta tggctatttt tcaatgtggg atacttttct acatgcattc agcggatttt
    28981 tagctggggg tgtcggcttt tcccttgttt atttgctcaa taaaaataca aaaaccatga
    29041 acttgactcc tttattacta gcagttgttt ccttctgttt ttcgatgaca gttggtgtta
    29101 tgtgggagtt tgtggaattt tcagcagata aattactgca attcgatatg caaaaagata
    29161 cgatcatcca gcaaatcaat agtgtggagt taagtaaaga cggaaacact gtctatcatg
    29221 ttccagatat cactcggaca atcattgaaa gtcaaaatgc agatggtaaa acagataaaa
    29281 caatcatcca aaatggttac ttagacgtgg gaatcatgga tactatgaag gatttatttg
    29341 ttaattttat tggagcagtt gttttcagtg tatttggtta cctctatagt cgaaacgatt
    29401 accaaaaatt tacgttcatc aagaatttta ttcctaaaaa aatcaaacga taaaacatgc
    29461 taaaaaacaa gagaaggggc agtgacaata cttttgtcac tgccccttct tttttgaatg
    29521 tatggcatgc cattagttat ccgatagtat taactcaaaa aagtaagata tgaggaatga
    29581 ctatttcgtt ttttatccca atactgagga cttatttcac catttcgtta tttatctaat
    29641 ttacttaaaa cctgcataac tttttcataa tctggattag gtgtgccgtc tagattttca
    29701 gcaataaaag taaaacccat ttttttataa agagcaatcg cctgatggct ccatgtctgt
    29761 gtgtgaagat agattggtcc gtccgtatgg agggtaggaa attcttgcaa gactctggca
    29821 gtcaatgctt ttgcgagccc ttttccttgg taatctggtt tcactgctaa ccaatgaaaa
    29881 accggataca cttgctctct tgattttttt cgccaagcgg tacaggttgc tactttttct
    29941 cctttttttg tctctacaaa aaacatcctt ctttcaagtt cttcaggata aggagcaaag
    30001 ttttgttgaa aatactcaag tgcttcatct gtcgtttgaa attccccaac ggaagtctca
    30061 atctccgccc aagcagattc atcttctttt tgataaaatc gaaattcaaa accttccgct
    30121 aaaggcgtga ttggaacatt ttgttgaagt ggtcttgtca tccagatttc tgcgtaaggt
    30181 aacgttttat ctaacatttt tctatccctc ctcgtctcca ttatgccaaa taacatatga
    30241 ctcagctact tatttgacta taacagatag agatataaat cagaaccagt catctgcgtc
    30301 aaattcattt cgattagcgt atacccatgt tcctgccata cctcgcatga aatctcctaa
    30361 agcagaagaa ggaatacctc caccaggtgc gggtgttccc ggactaggaa gtggtacttg
    30421 cggctgcaga tgctcatcgg tggaatcaat agttgacaag cgttttttct tcgtttcctt
    30481 ctggtcatct gattccttct gatcttccga ctgtttagca acaaattctt tttctgattg
    30541 ttgttttatt ttaggctcta aaatttcatt ttccaatcca gaaacttgtg gggccaaatg
    30601 agcttcttgc cttatcgttt tattagattc tgagattttt ctagatattc ttgctaactc
    30661 taggcttctt gtttgtttta ctttccctgt tggagaaact gcatgagcca tttgttgttt
    30721 tttttctgac aagctttctt cttgtctttt ttgttctttt tgatctatct gtttgtttaa
    30781 tggtaaaaca tgtaatagtg actgagcatg gagttcttgg agtgaatacg ggtcatgata
    30841 actatacata atcgtaaaat cacctgtttg tttggtcaaa taaccatcct ccaatggtac
    30901 ttcattgatt gtaaccgata catcctttaa cggtacgggt ttacctaagg aatttgttgc
    30961 tgattggatc aactcttctt tgtttatttt ttcgtttgga tgaacaataa gatcatgacc
    31021 ttctaatgaa cgattgtctg gtatataaac ataagtaaag gtaatttccc ctcctgattg
    31081 cttcctatta ttcatcagtt ctgagtgaag tacttcaagg atctccgacc agtgactttt
    31141 tctgtctaat ccgtttgctt gcatccaatc agaaatagaa gtgactttcc cattttgttc
    31201 ataagtcgat aaatctatat ttggcactcg atcagaaaat tcagcaggta ggcgcaaatc
    31261 aggaatacga tttacactac tcatatgtgt ttctgcttga agttctttat ttgtttgact
    31321 atctataaaa tgagtgatga cagtcgatga agcagcagat gcttctacat aaactacagc
    31381 tgttgtttct gccacatttg atgttttcga gtctatataa gttaatacaa cgggatattc
    31441 tcccggagtt gtagtatcta ctgtcccgtt cattttgatt tcttctttat ttcctgaagt
    31501 tccatcgctt tttgttacat attcaacaag atctttaggg gcgtaactct ctcctgttct
    31561 taagtgaaga tcttttcctt tgatagctgt ttgatcagca cgaacatgga tcacagcaga
    31621 tgcagtcatt gtttttaaag caattggatc aaaataggac aaggaaatag tagatgttcc
    31681 tgtattagtc gtatccacga tattcccatt gtttgaaatt actttggaca tatctccttg
    31741 tgttccatct gcgttcttca gcctttctac cagatcagat atcgaaactt ttgtccctgc
    31801 cagaacatcg attttctttc tttcaaactg tgaataatct ttttcatata cataagaaac
    31861 ttgtgcgctt ccaccgtcct ttatatctgt caaagcatga ttcaaaatat cagtgatctg
    31921 ttttaactga tcaccttttg taggatcagt catatcggaa aagatagaaa gcggcacact
    31981 gcttccggtt tccgatgtcc ataatgtttt gttaggaatt aaccagtagt ggtttatcgt
    32041 tggaggataa ctgactttat tataggaagt caatgcagga agtagctgtt ttccatttgc
    32101 atcagtgaaa gtatgagtaa tagtgatagg ggaatcagtg gtctcagaaa cagaggtacg
    32161 tacgaccttg atggtttgtg tcgttgcctg aacgggtaca tgcatataga cacctacaga
    32221 taaactgatc agcatcgtgc gcatcataaa cttaacgtag tgtttttcag aacacgaccg
    32281 ttccttatct aaacgacaag cgtgtttatt tagttgtttt gaacgtcttt ttgaacacat
    32341 ttattcttag tcctccctac tcttgtctaa acatgaagta gtaattttca taagatgatt
    32401 tcattatata aataaaatca aaagaagatg gactattagg agagtatttt ttttgatttt
    32461 ttattgtttc aagaaaatcg gaataataac ttatgtactt tttaattttg ttaagtaata
    32521 tatctagtta tatctagtta tatctagtta ccttttcttt gaaaaaaaca taaatcagct
    32581 aataaatatg tgagacaaag ctgccatcca taaatactag ctgatttttt cagttaaatg
    32641 tctatttttt tctctgatga tggtatttcc aaaatattcc cagtcatctg gagtcggtgg
    32701 atttttccaa attatctgtt ctttattaaa tttttcaagt aaacaatcag ataaataaat
    32761 attcgtacga gaagtgattc gactctcaat cacaatattg taatttttaa atcctttcac
    32821 ttgagaaata atgtaatcgg tataagcaga tccttgcgaa aaatcaatac agacatgaat
    32881 cggtgcttca aaatatgata ccggacaaat accgaccaat aaaaagagat aatcataaaa
    32941 taagcgaatc atgaaacgtt catcttttcc caagaaatag cgtttattct cttgtatgac
    33001 cttttggatt gctgtactga atattggata cgtctcgaag aaaaactgta gctgcttttt
    33061 agacgtaaag ctagtcatct caaagtcgaa tatccaattt tttcgattga catgcatcat
    33121 acccatacga agttcttttc gtatatatag tctttcttct tcagagattt caatcgaaaa
    33181 tggtaattga tcaatcaatt ccactgacat tttttgacta atcatgtgga tatcatgaaa
    33241 atgagcttcc gcaagtccaa atgcgccatc taattcaaat tcttcttccg tgatcaaaaa
    33301 caacatgata taagaaatct catcaatgat ctgctcttta gggatatgaa gaaaagaaat
    33361 atgtgataaa tccttgatga tcttcattcc ttctgagctc ttaaagtatt catctgaaaa
    33421 gaaacgtttt ccgattggtt gattcccata ggccctcaac aaactaatag tggttagcaa
    33481 attgaatttg attcgttttg ttgcagacag ttttaaattg aacagatatt caaaatattg
    33541 cacgatactc tttgcttcat tcatgacgct ttctctaaat ggcatagaaa aaccattaaa
    33601 gaccccgaaa tataccccaa ataatacgtt ccgtatgttt atttcttccc caactaatat
    33661 gtttttcttt aactttattt gatgctgttc aagaaaagag actaattctc ttctttttac
    33721 ataggctctt gatatgctta aaaaatgatt ctctgcaaat ttttcgatcg ttacttttga
    33781 atccacgatc tccgttaaca gtcgagcaat ttttgatcgt tgaaagtaga ttcttcttaa
    33841 atttttgata tccgtcaaat tcagacgttc gacatggatc tctgcttctt ctgaaatttg
    33901 gatctctggc tttgttttga attcagtaaa ttctttattt aattctatga tataatttct
    33961 tgttttaaat ttagacaaac ctaatgtttc atataactta ggcagcacta cataattctt
    34021 tttctcaaat tctaaatatc tagctagcag cagtttttct ctatcttcct cttctataag
    34081 gtaatccaac ttcatatcct acacctcaaa aaatgcctca taccaattac ttgatatgca
    34141 gatgaaagtt catcttttca cctatactga ttttatgatg gattatgctt gttttttcat
    34201 cagttattct cattttttat cttttttttg agaatattgc aaaaaatgga aaaatttatg
    34261 aggaaatatt ctatattttt tgttttattg tgttaaaatg tacaagattt gcgccatttg
    34321 cgtaaacaac cacaaaaaag agcaggacgg ccaccgtcct gctcttttac ttattttaag
    34381 ttccattact tattaattgg ctaaacttct gcttgtttct gatattgctt gtttttctcc
    34441 aatgatccgc acttctgttt ctaaagacac atcaaatttt tctttgatta cttcttggat
    34501 gtgcgcaatc aattcaatat aatctgtcgc tgtcgcatga tcgatattga cgatgaatcc
    34561 agcatgtttt tcagagactt gtgcaccgcc ccatttcagg ccttgcaatc ctgcttgttg
    34621 gatcagctga cctgtatagt gtcctactgg gcgcttaaag acacttccgc atgaagggta
    34681 ttctaatggc tgttttgatt gacgcaattc ggtcaactca tccattcttg ctttgattgc
    34741 ttcataatcc cctgtttgca aactgaatcg agcttccaat acgatagcac gtaattcttg
    34801 gactttactg tgacgataag aaaataccat ttcgtctttt gtcaaagttt tcaatgttcc
    34861 atcttcaagc aaaagatcca cttcagcaaa aacatctttg atctctccgc catacgcacc
    34921 tgcattcata taaaccgctc caccgacact tcccgggatg ccgcaagcaa attcaaatcc
    34981 agtcaatgat tctgccaaag ctgcataagt cgtatcaatc agtgaggcac ctgcttccgc
    35041 aatgaccatc gttcctttga catgaatctg tttcatttca gtcagcatga tgactacacc
    35101 gcgaatcccg ccatcttgaa cgatcagatt gcttgcattt cctaatacca tccaaggtat
    35161 atcatggatt cggcaataat cgatgatttg ctttacttct tcttgttttt tcgggaatgc
    35221 aaggacatca gctggtccac ctgttttcgt aaacgtatag ttcatcaatg gttcatcaaa
    35281 caatatagta atcgtggcta agctttcaac tatttcttct ttattcactg aggattttcc
    35341 tttcttttct caaacgtcct cattattcta tcacgcttaa tacaatcttg ccagtcttgt
    35401 tcaaagttga tgacggtagt gatctttaag cacttcctca cataattcat gacttcttac
    35461 aacttctttt tgtttaagca attctgtttc cgatttacct aaacggatct gagaaaagaa
    35521 ggcctctacc attggctcaa acccgcgttt gactagcgtg tttgtccagt cgccaaattc
    35581 tttcactttt tttccatcag catcttgaat gacaagctgg gtcagatcgt ttacttcata
    35641 agtaccattt ttacttgtta cttgatattt ttctatatta gcgccacttg ctaaatccat
    35701 cgttaaaata gccgtttgat tttgtgtttc taattgtaaa atggcatatt ccaaaaattc
    35761 ctttgtttct cttatctggt attttgttct caaaatgggt tcatctaata aatacacagc
    35821 tgtatcaata agatgtaaaa acaaatcata aaggacgaac tctgtcgttt cttttgccgc
    35881 tattcgattt ttttgcaggt ggatcaaccg cttatctggg atacgtttca attcttctac
    35941 cataggagca aagcgccggt tgaaaccgat catcaaaatt atttggttct tatcagctaa
    36001 ttcttgcaat tcacgaactt catttagatg gacactcagt ggtttgtcaa tataaacatg
    36061 gataccattt tctagacatt ttttggctaa ttcataatgt acttttgttg ctgcgtggat
    36121 catacatgct tcgatttttt cttctaaaag ctcatcgatc gtttcatata gatgttggaa
    36181 cccgtactct ttttgaattc tttcttttgt ttctttattt cttgttgcaa aataaaaatc
    36241 aagtgttcct tgttttttcg cataagttgg taaatatgct ttttctgcga tattccctac
    36301 accgattaca ccaatcttca tctactttcc tcctggatca tttagttact ttcatcttac
    36361 accatttttt actaaaatga ggtacaatag tatcgcaaag gtaaggaaat taattcgaag
    36421 gagtgtgctt ttattgaaat ttatctcttg gaacgtaaac gggcttcgtg ccatcgtaaa
    36481 taaaaatttt ttagaagttt ttcatgagtt agacgccgat tttttctgtc tgcaggaaac
    36541 gaaactccaa gcaggacaaa ttgatttaga tcttccaggt tattatcaat attggaatta
    36601 cgcggaacga aaaggctatt ccggcacagc gatttttgct aaaaaaccag cattgaatgc
    36661 cacttacgga atgggtatcg atatccatga tacagaaggc cgtctgatta ctttggaata
    36721 ttccgatttc tttcttgtaa cctgttacac gccaaattct caaagcgaat taaaacgttt
    36781 agattaccga ttagaatggg aagaagcctt ttataattat ttggaaaatc taaaaaaaca
    36841 aaaaccagtc atcgtgtgtg gggatctaaa tgtcgctcat caaaagattg atttgaaaaa
    36901 ctggaaaacg aatcaaaaaa atgctggatt cactccagaa gaaagagcgg ctctttctcg
    36961 actgttggat aacgggttta tcgatacatt ccgttatttt tacccaaccc aggaaggtgt
    37021 ctactcttgg tggaactacc gattcaattc aaggaaaaac aatgctggtt ggcggatcga
    37081 ttactttttg acgagcaaag atttagagcc aggactagct gatgcaaaga tccatacgga
    37141 cattatgggc agtgatcatt gtccagtaga attagatttg aaataaagag gttgtgaaaa
    37201 agtcgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca cattttgcat
    37261 aaatttggca taataccgag aaactggctt ttgaacactg tttatcgaga gattgtgaaa
    37321 aagctgtcct gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg
    37381 tttggttggg cttattaccg cagatacaag cttttgaaca ccgtttatta agaggttgtg
    37441 aaaaagctgc actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    37501 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta ttaagaggtt
    37561 gtgaaaaagc tgcactgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat
    37621 ttttcgtttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattgagaa
    37681 gttgtgaaat cagcgtcctg acctgagtat tagagaaaca aatggcaaaa tagttcctca
    37741 tattttgcta ttttttgagc taataccgag ggtcagctga ttgaacactg tttagtggag
    37801 aggttgtgaa atcagcgtcc tgacctgagt attagagaaa caaatggcaa aatagttcct
    37861 catattttgc tattttttga gctaataccg agggtcagct gattgaacac cgtttagtgg
    37921 agaagttgtg aaaaagtcgc ctactttcga gtcgtaagaa atttttttga aaatggttcc
    37981 tcacaacttt gcataaattt gacttaatac cgagaagtca tgatccccat ctaactccaa
    38041 atcacaagga atgagttcaa aaactagctt ttctcaacaa atattacata aaaaattcta
    38101 tgttttttgt taaatttatt tgcttttttc aaaagtatgt tacagtaatt tcccaaggag
    38161 gttttacaga aatgaatttt gttgccatgg attttgaaac tgccaatcat cagccttata
    38221 gtgcttgttc tcttgcgcta gtcatggtaa aaaatagcca gatcgttgat gaattctata
    38281 cattgataca gcctgagact ccttttttct ggcgaaatgt ccaaattcac ggaatccatc
    38341 aagaagacgt acgcaatgcg ccgaaattcc cagaagtctg gcaaactatc caaccatatt
    38401 ttcaaaaaaa tcgtttagtc gttgcacata atgctgcttt tgatacaaag gtcttagcgg
    38461 gatgcttaga ttattatcat cttgaacagc ctaattatct ttctttatgt acagtgaaaa
    38521 gtagccgtcg cctgtttcct gaatttccaa atcatcgatt gaacactgtg tgcgaaaatt
    38581 tgaacatcca attagatcat caccatgatg cattggaaga tagtcgtgca tgtgcggaaa
    38641 tcctgcttta tcaagaaaaa aaattcggga cagatccatt gaaaaaactt gtgactataa
    38701 agtaaaagaa tacttatgaa acacacaaag aggtcgtgag cctgccgttt cactccgagt
    38761 cacaaggagc aatttcaaaa aatagcttct catgtttatt aaatattgtg actggtgacc
    38821 gaggagctgg caggagaaca ccgtttattg gagaggttgt gaaaaagctg ttctgcatca
    38881 agtaataaga acagccaaac aaaaatagct tctcatattt ttcatttggt tggacttatt
    38941 accgcagatg caagcttttg gacaccgttt accaagaggt tgtgaaatca gcgttttgac
    39001 ctgagtatta gagaaacaaa cggcaaaata gttcctcata ttttgccgtt ttttgagcta
    39061 ataccgaagg tcagctgatt gaacaccgtt tattcaaaaa aaatggactg cgacacgact
    39121 tttgtcacag tcccttcgtg tgtttttctg ccttctcaaa aggatgacag tttctcactc
    39181 ttttcctatt tcttctattc aatcaaataa ctcattttat atacatctaa aaattcacct
    39241 agatctgttc ttgcccctct aggcatgacc gcttcgattt ggaagcccat ttttcggtaa
    39301 aggtgtacgg ctctttcatt acgaacttga acgtcaagct ccaatcgaaa aagtacaccc
    39361 atttccttcg cccaactgat gatttcttct agcataagag tgcctagtcc cattccccaa
    39421 tattcctgca gaatactgat accgacttct cccacgtgag acaaacgaaa ttgactgtct
    39481 gccttgacag atgctgttcc aataatcgtc ccttcataga ttgcaagcag caataaatta
    39541 ttattgcttt cgtatatata atccaactct tcttctaagg tttctggtgg taacaggagt
    39601 tctgcttcat ccaaaactaa aaattctgtc tccttattaa cttgtcccat catcaaaaga
    39661 atgtcttttg catctcctgg cactgcttcc cgcaagatga tcccaacttc ttcactcatg
    39721 attttcagcc catttttcta gaattcgctg tttgaaggtt tcactttgct ccccgtatga
    39781 gattagtttc acataccgct tttctaaatc tgtatcactt ttttctaaaa tcagttccaa
    39841 ataatcctcc ggcagtgctt cttctaatag atttccccat tcaacaacgg aaagcccatc
    39901 accttcaaaa tattcatcta accctaaatc tgctccgcta gctgctaccc gataaatatc
    39961 catatgatac aacggaatcc gaccttgact atattctcta ataatcgtgt atgtcggact
    40021 tttgatcatt tgcgttatcc ctaatccttg ggcaattcct ttcgtcaacg ttgttttacc
    40081 cgcacctaga tcaccagtca atatcagatt gtcacctggc attgcggaat gaccaattgc
    40141 ctctgcgaat tgttctgtca ttgttaatcc tgatagttcg atcatttttc atcttctccc
    40201 gctcttcttt ctttttgcca gtatatcgcg taatgaagtt tttttaaaga aaaaatgaac
    40261 tagtcaagaa cagcagctgc tgtttttggc tagttcgcgt gtatttgtta atcaatcaat
    40321 gtttgtgctg ctgtgataat cgataattta tatacatctt cttcatttgc tccacgagac
    40381 aaatcagaaa ccggtttgtt caagccttgt agaattggtc cgattgcttc aaagttaccg
    40441 aaacgctgag caattttata gccgatattt cctgactgca attctggaaa tacaaagact
    40501 gttgcttgac cagctacttc tgaatctggc gctttcagtt gtgcaactga aggaacataa
    40561 gaagcatcaa attgcaattc gccgtcgatc atgtattgtg gcgctagttt tttagcgatt
    40621 ttagttgctt caactacttt gtctacttct ggcgatttcg ctgagccttt tgtcgagaag
    40681 ctcatcattg ctacttttgg ttcgatatcg aacaattctg ctgtttttgc agaatctacg
    40741 gcgatttcag ccaattcttg cgcagttgga ttcacgttga tcgcacaatc cgaaaagaca
    40801 tatttttctt gatctcttcc acgtaccatg atcatcgctc cgcttgtccg actgatgcca
    40861 ggctttgttt tgatgatctg aagtgctggg cgaacagtgt cgccagtcga atggatcgct
    40921 ccagagacca ttccgtctgc aatccccata tacgtaagca tcgtaccaaa gtaattcaca
    40981 tcttttaaaa tcttttctgc ttgttctttg gatgcctttc catttctacg ttcaacaaaa
    41041 gtatccacca tttcatccca cttatcgtaa ttatcagggc tgatgatcgt aaagctagat
    41101 gttttgattc ctctggcatg cgctgcattt cttatttctt cttcgttccc tactaaaatg
    41161 ggttccacaa gttcttctgc tttcaaccgg gcagctgcgc ctaaaatacg agcatcagta
    41221 gcttccggga aaacgatttt gatcccacgg cgaacaattt taaatcttaa actatcaaac
    41281 aattccacaa gatgacctcc agacgttttt atatgtatta tcatacacta ttccagaaaa
    41341 aaagaacagt ttattttatc tgtatcagtc aaaaatgctg gaaaaattaa gtttttcaca
    41401 tacaaagcga actgcactat aacaggaaag cgctgtttta ttacactgtt tcaggcagtt
    41461 gccaatcaat cggttcttct cctaacgcaa ggagcgcatc attcgttttc gagaagggtt
    41521 tggaaccaaa aaagccacga cttgcagata acggactggg atgtggagat gttatgatga
    41581 tatggcgact cttatcgatc attttgattt tttcttgtgc cggttttccc cacaagataa
    41641 acacgattgg tttttcccgt tcatttaatt tttcaatgat cgtgtctgtt aatctttccc
    41701 aacctttccc gcgatgagaa tacgcttgcc cttcccgaac ggtaagaacg gtgttgagta
    41761 aaaggactcc ctgtttagcc catgacacta gatttccatg ttgaacaggt gcgattccaa
    41821 gatcatcata aagctcttta tagatatttc ttaacgatgg cgggatcttt acgccaggtt
    41881 gcacagaaaa agataagcca tgagcttgat tttctccatg ataaggatct tgtcctaaaa
    41941 tcaccacttt aacttcttca taaggagtca attccaatgc ttcatagata tgatacatat
    42001 ctggatggat cttttgggac gcatattctt tttttaaaaa ttctcttaga tgcagataat
    42061 aatcttttga aaattctgag gacaaaactt cttgccaact gttatgaatg atttctttca
    42121 aaaactccac ctcctaataa aaagaataac tcacattttc ttcaatcaca agggacaatc
    42181 ttcaccctca gcacttgatt aatatggtaa actaggaaca agaagcagaa aggaacgata
    42241 atcattatga tcaaattaat tgcatcagat atggacggca cattattaga tgcccatatg
    42301 agtgtttctc ctgaaaatgc cgaggcgata cgttttgcaa atgatgccgg tgttgagttc
    42361 atggtcgcta ctggtcgaaa ctatcaagaa gctcgcgcag ctttagatga ggtaggaatc
    42421 gattgtgcga tgatcacttt gaacggggca caggtatttg ataaagaagg aaattcattg
    42481 tttaccgtgt cgattccaaa taatcaagca atctctgttt tagatattct agatgctaac
    42541 ggtatttact atgaagtagc aaccaacgat ggtctttatt ctgaaaatca agcgaaacga
    42601 attgaaagtt ttgcttccat ggtggctacc catttacctc accttacgta taaaatggcg
    42661 attgccatgg cctcagctaa gctggagtta ttgcacatca catacgtgga cagtattcgt
    42721 gctattttgg aagaaaagaa tctggaagtt ttaaaaatta tttgttttca tacagaaggg
    42781 ccagctgtat taggtccagt tggaaagcag atttctcttt taggcgatct agccgttact
    42841 tcctctggtc aaaacaatat cgaagtgaac cataaaaacg ctcaaaaagg aattgctgtt
    42901 gcccatgtcg ctcacgagcg tgggatttct ttagaagaag tcatgacgat tggcgataac
    42961 ttcaatgatg tcagcatgct gcaagtagca ggagtcagtt tcgcaatggg aaatgcagaa
    43021 atcgaagtaa aagattatgc caaatataca acggacacaa accttgaatc tggcgtagga
    43081 aaagccatat tgcgcgcgat tgcagaagac ttgtagtttt atctagaaaa gagggatata
    43141 gatgtcagaa tttttcattc aggaaaagca gcttggacgt gcaactcgga caattgtcaa
    43201 aaacgaaaaa ggacattccc tgtttttgat ggttggtcgc tggggaacaa agggcgatgc
    43261 attgtctctt tatgccatga atggcgatct cgttgctcac atcaagcaga taagcctgac
    43321 attcggtacg cgttttgagc tgtataaaga gttcgaaaag gtgggaacca tgcagaaaat
    43381 attcaattgg cccggtgact tttattatat tcgtagactt cactggacag tccaaggtga
    43441 tatctataat catcaatatc aaatccatca tttcaatcag caaatcatga aaatggataa
    43501 agcaacactt ttttcaggag attactatgt attggatgtc tcaaatgatg aagatgctcc
    43561 agtttgtatt tgtattgctg cggttttaga ttactggctc taccgtaaag acaaaagtcg
    43621 cgataagcct gtttcttacc gacttaactt aagttaaaaa gatgtacctg aaatgcggaa
    43681 atacgcattt caggtacatc tttt
//
LOCUS       DBGZHO010000014        43672 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.014, whole genome shotgun sequence.
ACCESSION   DBGZHO010000014 DBGZHO010000000
VERSION     DBGZHO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.014"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            598..1287
                     /locus_tag="ACN3HL_000998"
     CDS             598..1287
                     /locus_tag="ACN3HL_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8005890.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="ACN3HL_000999"
     CDS             1274..2482
                     /locus_tag="ACN3HL_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HHC8005891.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="ACN3HL_001000"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="ACN3HL_001000"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HHC8005892.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ACN3HL_001001"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ACN3HL_001001"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HHC8005893.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="ACN3HL_001002"
     CDS             complement(6585..7280)
                     /locus_tag="ACN3HL_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HHC8005894.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ACN3HL_001003"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ACN3HL_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HHC8005895.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="ACN3HL_001004"
     CDS             complement(8479..8670)
                     /locus_tag="ACN3HL_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HHC8005896.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="ACN3HL_001005"
     CDS             complement(8691..9581)
                     /locus_tag="ACN3HL_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HHC8005897.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="ACN3HL_001006"
     CDS             complement(9568..10335)
                     /locus_tag="ACN3HL_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HHC8005898.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ACN3HL_001007"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ACN3HL_001007"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HHC8005899.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ACN3HL_001008"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ACN3HL_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HHC8005900.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ACN3HL_001009"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ACN3HL_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HHC8005901.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="ACN3HL_001010"
     CDS             14906..15289
                     /locus_tag="ACN3HL_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005902.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /gene="jag"
                     /locus_tag="ACN3HL_001011"
     CDS             complement(15457..16215)
                     /gene="jag"
                     /locus_tag="ACN3HL_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HHC8005903.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="ACN3HL_001012"
     CDS             complement(16233..17051)
                     /locus_tag="ACN3HL_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HHC8005904.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ACN3HL_001013"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ACN3HL_001013"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HHC8005905.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ACN3HL_001014"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ACN3HL_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HHC8005906.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="ACN3HL_001015"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="ACN3HL_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HHC8005907.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="ACN3HL_001016"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="ACN3HL_001016"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HHC8005908.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="ACN3HL_001017"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="ACN3HL_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HHC8005909.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="ACN3HL_001018"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="ACN3HL_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HHC8005910.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="ACN3HL_001019"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="ACN3HL_001019"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HHC8005911.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="ACN3HL_001020"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="ACN3HL_001020"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HHC8005912.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /gene="rpsF"
                     /locus_tag="ACN3HL_001021"
     CDS             27093..27392
                     /gene="rpsF"
                     /locus_tag="ACN3HL_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HHC8005913.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="ACN3HL_001022"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="ACN3HL_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHC8005914.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /gene="rpsR"
                     /locus_tag="ACN3HL_001023"
     CDS             27980..28216
                     /gene="rpsR"
                     /locus_tag="ACN3HL_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HHC8005915.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="ACN3HL_001024"
     CDS             28359..30332
                     /locus_tag="ACN3HL_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HHC8005916.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="ACN3HL_001025"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="ACN3HL_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HHC8005917.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="ACN3HL_001026"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="ACN3HL_001026"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HHC8005918.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="ACN3HL_001027"
     CDS             33211..34503
                     /locus_tag="ACN3HL_001027"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HHC8005919.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35239..36102
                     /locus_tag="ACN3HL_001028"
     CDS             35239..36102
                     /locus_tag="ACN3HL_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHC8005920.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36231..37853)
                     /locus_tag="ACN3HL_001029"
     CDS             complement(36231..37853)
                     /locus_tag="ACN3HL_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHC8005921.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38102..38623
                     /locus_tag="ACN3HL_001030"
     CDS             38102..38623
                     /locus_tag="ACN3HL_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HHC8005922.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="ACN3HL_001031"
     CDS             complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="ACN3HL_001031"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HHC8005923.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40704..41522
                     /locus_tag="ACN3HL_001032"
     CDS             40704..41522
                     /locus_tag="ACN3HL_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HHC8005924.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41625..41822)
                     /locus_tag="ACN3HL_001033"
     CDS             complement(41625..41822)
                     /locus_tag="ACN3HL_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005925.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41991..42569
                     /locus_tag="ACN3HL_001034"
     CDS             41991..42569
                     /locus_tag="ACN3HL_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HHC8005926.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42664..42801
                     /locus_tag="ACN3HL_001035"
     CDS             42664..42801
                     /locus_tag="ACN3HL_001035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005927.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT        13330 a         8331 c         8604 g        13407 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaacaaacgg tgttcaaaag cttgcatcta cggcactaag
    34681 cccaatcaga tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc
    34741 agagcagctt tttcacaacc tctccactaa acggtgttct cctgccaact cctcggtcac
    34801 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    34861 agctaaacgg caggctcaca acctcttggt aaacggtgtt caatcagctg accctcggta
    34921 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc cgtttttttc tctaatactc
    34981 aggtcaaaac gctgatttca caacctctga ttcacggtgt tccagaagta gcttctacgg
    35041 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    35101 ttgaagctga ccacttctgt cacaacctct tattttgatt agaacttgcg aaaataaacc
    35161 ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac
    35221 gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac
    35281 catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa
    35341 gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa
    35401 aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt
    35461 tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc
    35521 tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag
    35581 atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct
    35641 gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat
    35701 tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt
    35761 aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg
    35821 gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc
    35881 cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat
    35941 gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag
    36001 ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc
    36061 tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg
    36121 taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat
    36181 cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat
    36241 aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca
    36301 gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata
    36361 aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc
    36421 aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta
    36481 gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca
    36541 ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag
    36601 aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga
    36661 tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc
    36721 caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt
    36781 gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat
    36841 atatcatcta aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag
    36901 tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt
    36961 tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat
    37021 tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct
    37081 tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa
    37141 tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat
    37201 actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc
    37261 aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc
    37321 aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca
    37381 ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt
    37441 aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat
    37501 tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt
    37561 tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag
    37621 tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta
    37681 acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct
    37741 gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca
    37801 tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt
    37861 cctcactttt atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa
    37921 aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa
    37981 aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt
    38041 tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa
    38101 aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact
    38161 tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt
    38221 tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga
    38281 gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg
    38341 cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt
    38401 atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag
    38461 tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt
    38521 cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt
    38581 tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata
    38641 aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat
    38701 ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga
    38761 agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt
    38821 ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg
    38881 gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggcg
    38941 cttgttattg atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa
    39001 ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc
    39061 aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc
    39121 ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag
    39181 ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact
    39241 taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc
    39301 attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa
    39361 taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc
    39421 agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc
    39481 ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca
    39541 gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc
    39601 accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat
    39661 ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac
    39721 aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc
    39781 agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc
    39841 gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt
    39901 tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag
    39961 caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg
    40021 ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt
    40081 atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat
    40141 gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattta gttcctggaa
    40201 agagttatag ttcatggatg tagaagcaac ttgtcctaag aacgctacta gaggcacatg
    40261 gtccatctgt gcatcataca aaccattgat caaatgtgtc gcaccaggtc ctgcagagcc
    40321 gaagacagcg ccgactttcc ccgttaattt tgcatctgca gcggctgcga gtgcgccgac
    40381 ttcttcatga cgaacttgaa tgtagttgat ttcggttttt tcttgatata gcgcatccat
    40441 aattgaattg aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc agctttcaag
    40501 aacttttacc attgcgattc ctgcattgat ttttgacatg gtgtttcact cctttagcaa
    40561 tgatgataca taaatttttt gtatctagag tatagaactt tttatcgaaa atcccaacta
    40621 attcgtcttt tcacaaaaat gtagtcatgt ttttgggaat atgctagagt agtacataga
    40681 tagattcaag agaggggaat ggcatggttg aatggctatt gagacttgaa ccttggcagc
    40741 aagcacttgc tgggacagct tttacttatt ttatgacagc tcttggtgcc gggttggttt
    40801 ttttctttaa agaaatcaaa aaagaagtgc taaacttgat gttaggattt gcttctggtg
    40861 tcatgattgc tgcaagtttt tggtctttgt tagatccggc tattacaaaa gcagaagaaa
    40921 atggagatat tgcttggcta gttgtaagta ttgggtttgg tttaggcggt gtgtttttat
    40981 atatggcaga taaaacactg ccccatatgc attttggacc acaacatgaa gcagaaggat
    41041 tgcctaccca tttaaaacgg acgatcttgc ttgttttttc tattacattg cataacattc
    41101 ctgaaggttt agccgtgggg gtagcattcg gtgcagcagc aactgcggat aatccgacag
    41161 ccgctatatt agccgctgtt tcggtggcgc taggtattgg tatccaaaac ttcccagaag
    41221 gagcagctgt atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag gcctttgttt
    41281 acggacaagc ttctggaatc gttgaaccaa ttgctggagt gattggagcg ctactagtaa
    41341 cgaaagtgga gctgctgctt ccttatgcac ttgcttttgc cgcaggagca atgatttatg
    41401 tcgtggtgga agaattgatc cctgaagcac agcagacatt gtccagcaaa cgtcattttg
    41461 cagtttttgg cgtcatgagt ggatttatca ttatgatgat tttggatgtg gcattaggat
    41521 aaataaaaaa aatatatatg atatatcaaa tagggccgcg aacttatatc gcgaccctat
    41581 ttttttagta agttatatca taatgaagtg aatggtatca tacattaata atagtttttt
    41641 ctatgtgtat ttcctttgat ccagcgaaca agccagatga taagtgcgat tgggattaga
    41701 actttgaccg caaaccataa aagcccgctt aggacactga caaaaagact gatgacgaag
    41761 ctagctgcaa ttagcactaa aagaaccatg aagatattta agaacatatt tttttgacgc
    41821 atacaaaacc ctcctcttgt tcattcttta ctatagaaaa agtataacag ggattgttta
    41881 aaaacacctc caactgaaga ctgattttta cttcatctac ttaaatgatc aaacaattgc
    41941 tttttctctg gtttatcatc taaaatagag cggaaaagga ggagaatatc atgcctaaaa
    42001 atcgtcttga agcatttaca gatgctgtaa tcgcgattat catgactatt ttagttttag
    42061 aacttcatga acctaacgga gacacgtggg aggcgctcgc tgcattaggt taccgatttt
    42121 ttatctatat tgtcagtttt atcattttag cgatttattg gaacaatcat catcatttat
    42181 ttcaagttgt acataagata aatggacggg tcttatgggc gaacagtttc tttgtttttg
    42241 cgctttcgct ttttccgttt gcaacttcat ggatcagtga gtacatcaat agcctggctc
    42301 cagaaatgac ttatggtttt gttaccttga ccgctaatat tgcgtattat atcttggcaa
    42361 aagaacttgt caaagcaaat aaaggccacg agaaagcatt gaaggcgatg ttgaataatt
    42421 acaagaaatc gtatctatcg attggtttga atgtgttagg aattgtctta gggtatttag
    42481 tagcgccagt agccgtgctg atcgcaaaca tcgtgattct agctgcttgg atcatcccaa
    42541 gtcgtaccat cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt aagagaaaaa
    42601 tatagaaaaa ataaataaac gatcaaatat ccgagtgata ctagtattca aagagggatg
    42661 cagatggatc aaaaaagaat tcatgtagga ctgattacta gttttgtcac gatgcttatt
    42721 tatttggatc aaggtcattt gacttggaca gtagttggtg tcgtaggatt tttgacatta
    42781 ttcacagcaa taaaaaaata aacatcttta tgtaatctga tgttctatct atttaagaaa
    42841 agcatgttta cagcagtatg attctgttgt aaacgtgttt ttatttgtgg aaaatttaat
    42901 ttttagaaaa gtgtatcgaa aaatagatag ttagtttttc cacagtggat aacttcgtaa
    42961 gagataaaaa taaaaaatta gtcaaagaag ggcgtataga tttcttttga taggagatat
    43021 acaacagaaa tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt gtggtttttg
    43081 gaataaaaaa ataacatatc tcattttacg cttttgttat tttatactta aaaaataacg
    43141 acacagaaaa taccgtgtct cagatttctc tactacttct aaaaactact gtttttttcc
    43201 tttgaaatgc cttcaaaaag taggatcagg cagaatatac tggcagaatc aaggagaagg
    43261 gagcctaaat aaggagaaaa accatagaaa atataaagta attacttata aaacaagctt
    43321 tttatagaaa aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat
    43381 tgagatattg actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt
    43441 tttgttaaat aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat
    43501 aatatagtag attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc
    43561 gtcatagata cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga
    43621 agacggacag ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa ta
//
LOCUS       DBGZHO010000015        42949 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.015, whole genome shotgun sequence.
ACCESSION   DBGZHO010000015 DBGZHO010000000
VERSION     DBGZHO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.015"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..449)
                     /locus_tag="ACN3HL_001036"
     CDS             complement(<1..449)
                     /locus_tag="ACN3HL_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8005928.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
     gene            793..1200
                     /locus_tag="ACN3HL_001037"
     CDS             793..1200
                     /locus_tag="ACN3HL_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005929.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            1214..1615
                     /locus_tag="ACN3HL_001038"
     CDS             1214..1615
                     /locus_tag="ACN3HL_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005930.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1617..1988
                     /locus_tag="ACN3HL_001039"
     CDS             1617..1988
                     /locus_tag="ACN3HL_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005931.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(2024..2326)
                     /locus_tag="ACN3HL_001040"
     CDS             complement(2024..2326)
                     /locus_tag="ACN3HL_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HHC8005932.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2584..2697)
                     /locus_tag="ACN3HL_001041"
                     /pseudo
     CDS             complement(2584..2697)
                     /locus_tag="ACN3HL_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3080..4312)
                     /locus_tag="ACN3HL_001042"
     CDS             complement(3080..4312)
                     /locus_tag="ACN3HL_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HHC8005933.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4566..5135
                     /locus_tag="ACN3HL_001043"
     CDS             4566..5135
                     /locus_tag="ACN3HL_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8005934.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(5313..5753)
                     /locus_tag="ACN3HL_001044"
     CDS             complement(5313..5753)
                     /locus_tag="ACN3HL_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HHC8005935.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5911..6675
                     /gene="map"
                     /locus_tag="ACN3HL_001045"
     CDS             5911..6675
                     /gene="map"
                     /locus_tag="ACN3HL_001045"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HHC8005936.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6707..7630
                     /locus_tag="ACN3HL_001046"
     CDS             6707..7630
                     /locus_tag="ACN3HL_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HHC8005937.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7706..8845
                     /locus_tag="ACN3HL_001047"
     CDS             7706..8845
                     /locus_tag="ACN3HL_001047"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HHC8005938.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8838..9638
                     /locus_tag="ACN3HL_001048"
     CDS             8838..9638
                     /locus_tag="ACN3HL_001048"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHC8005939.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9638..10465
                     /locus_tag="ACN3HL_001049"
     CDS             9638..10465
                     /locus_tag="ACN3HL_001049"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHC8005940.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            10470..11177
                     /locus_tag="ACN3HL_001050"
     CDS             10470..11177
                     /locus_tag="ACN3HL_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8005941.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            11277..12143
                     /gene="rfbA"
                     /locus_tag="ACN3HL_001051"
     CDS             11277..12143
                     /gene="rfbA"
                     /locus_tag="ACN3HL_001051"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HHC8005942.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            12157..12729
                     /gene="rfbC"
                     /locus_tag="ACN3HL_001052"
     CDS             12157..12729
                     /gene="rfbC"
                     /locus_tag="ACN3HL_001052"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HHC8005943.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12751..13779
                     /gene="rfbB"
                     /locus_tag="ACN3HL_001053"
     CDS             12751..13779
                     /gene="rfbB"
                     /locus_tag="ACN3HL_001053"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HHC8005944.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13877..14728
                     /gene="rfbD"
                     /locus_tag="ACN3HL_001054"
     CDS             13877..14728
                     /gene="rfbD"
                     /locus_tag="ACN3HL_001054"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HHC8005945.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14763..16796
                     /locus_tag="ACN3HL_001055"
     CDS             14763..16796
                     /locus_tag="ACN3HL_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8005946.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMITFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16840..18120
                     /locus_tag="ACN3HL_001056"
     CDS             16840..18120
                     /locus_tag="ACN3HL_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HHC8005947.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            18330..19136
                     /locus_tag="ACN3HL_001057"
     CDS             18330..19136
                     /locus_tag="ACN3HL_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8005948.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            19148..20368
                     /locus_tag="ACN3HL_001058"
     CDS             19148..20368
                     /locus_tag="ACN3HL_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8005949.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            20358..21944
                     /locus_tag="ACN3HL_001059"
     CDS             20358..21944
                     /locus_tag="ACN3HL_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8005950.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21983..24121
                     /locus_tag="ACN3HL_001060"
     CDS             21983..24121
                     /locus_tag="ACN3HL_001060"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8005951.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(24489..25472)
                     /locus_tag="ACN3HL_001061"
     CDS             complement(24489..25472)
                     /locus_tag="ACN3HL_001061"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HHC8005952.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            25850..27241
                     /locus_tag="ACN3HL_001062"
     CDS             25850..27241
                     /locus_tag="ACN3HL_001062"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HHC8005953.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            27257..28297
                     /locus_tag="ACN3HL_001063"
     CDS             27257..28297
                     /locus_tag="ACN3HL_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8005954.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRKIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            28316..29401
                     /locus_tag="ACN3HL_001064"
     CDS             28316..29401
                     /locus_tag="ACN3HL_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HHC8005955.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            29434..30396
                     /locus_tag="ACN3HL_001065"
     CDS             29434..30396
                     /locus_tag="ACN3HL_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HHC8005956.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            30389..31816
                     /locus_tag="ACN3HL_001066"
     CDS             30389..31816
                     /locus_tag="ACN3HL_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HHC8005957.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            31818..32888
                     /locus_tag="ACN3HL_001067"
     CDS             31818..32888
                     /locus_tag="ACN3HL_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HHC8005958.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            32875..34296
                     /locus_tag="ACN3HL_001068"
     CDS             32875..34296
                     /locus_tag="ACN3HL_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HHC8005959.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            34309..35316
                     /locus_tag="ACN3HL_001069"
     CDS             34309..35316
                     /locus_tag="ACN3HL_001069"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HHC8005960.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            35328..36332
                     /gene="neuB"
                     /locus_tag="ACN3HL_001070"
     CDS             35328..36332
                     /gene="neuB"
                     /locus_tag="ACN3HL_001070"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HHC8005961.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            36329..37477
                     /gene="neuC"
                     /locus_tag="ACN3HL_001071"
     CDS             36329..37477
                     /gene="neuC"
                     /locus_tag="ACN3HL_001071"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HHC8005962.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            37450..38127
                     /locus_tag="ACN3HL_001072"
     CDS             37450..38127
                     /locus_tag="ACN3HL_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HHC8005963.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            38078..39259
                     /locus_tag="ACN3HL_001073"
     CDS             38078..39259
                     /locus_tag="ACN3HL_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HHC8005964.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            39272..40249
                     /locus_tag="ACN3HL_001074"
     CDS             39272..40249
                     /locus_tag="ACN3HL_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8005965.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            40249..41157
                     /locus_tag="ACN3HL_001075"
     CDS             40249..41157
                     /locus_tag="ACN3HL_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HHC8005966.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            41158..41910
                     /locus_tag="ACN3HL_001076"
     CDS             41158..41910
                     /locus_tag="ACN3HL_001076"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HHC8005967.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            41915..42862
                     /locus_tag="ACN3HL_001077"
     CDS             41915..42862
                     /locus_tag="ACN3HL_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HHC8005968.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        14394 a         6526 c         8277 g        13752 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcacct cttttaatta gatttctagt
      481 ctaacttttg gggtgcacat catttttgag gggaagtaca tatagttgtt gatatagttg
      541 ctaatattgt tagctaattt gttagtaaaa ctgtatacga atttagatag taaaaaaaca
      601 gtttgttcct tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat
      661 atacttataa atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta
      721 ttgttaaact aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat
      781 taggagaaat caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag
      841 caatttggca ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct
      901 ttaattccta ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca
      961 gaaaagataa aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct
     1021 acgggtgaag tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac
     1081 gccagaaatg tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga
     1141 actgagattg gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa
     1201 ggagacgata cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat
     1261 aaattttgct gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga
     1321 tgcaagttct actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga
     1381 gattaacaca atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa
     1441 aagaaaagct gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat
     1501 caaaacaaca tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt
     1561 attatctgac tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt
     1621 ttgactttaa tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt
     1681 ctaaagaatc ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat
     1741 ctgatgagta tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa
     1801 gccaccaaac cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac
     1861 ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa
     1921 ccattacgaa aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac
     1981 tcacctaatg aatttcaagc gagtttgttt gttatttttt tatttaatct ttgtatcttt
     2041 ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgcta cgtgcgtccg
     2101 gcacgtcagt cacgatatca aacaaaaagt atacaccctt cttcattcta gttttcgcag
     2161 caggaatttt gaaatagttc ttattagaat agtagagatt gattaataag ctatcttcga
     2221 ttgctaaaaa gaaaacttct gaattccata ctttataaaa atctttgata aatctattcg
     2281 aagggtcaaa tttaaaccat aattgtgttt ttccttccat cagcataaaa gttcacctca
     2341 aaaagagtat acgaacgaat gttctttttg tgaaggcgga atttaatata ctgaataata
     2401 gaaaacaagt acttgtgcca aattatgtgc caaaaaaatt cgaattcaac aaaatgtaaa
     2461 caaatagaaa accttctata ttaagatttc ctgcaataac aaacacaaca gaagacgtgt
     2521 aatagttagt caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt
     2581 tgtataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag
     2641 tatatttact ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa
     2701 cagtcgaaga gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt
     2761 gtagttgatt ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag
     2821 tcctatccaa cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt
     2881 aaagccaatg ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt
     2941 taatacttac aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg
     3001 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
     3061 catgtgtgcg aaagtatact caagcccaat cgccgtttcg gaaaatcggt actgtagagc
     3121 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
     3181 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
     3241 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
     3301 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
     3361 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
     3421 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
     3481 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
     3541 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
     3601 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
     3661 taccgggagc agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt
     3721 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
     3781 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     3841 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     3901 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     3961 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     4021 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     4081 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     4141 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     4201 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     4261 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     4321 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     4381 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     4441 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     4501 aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta aggagattaa
     4561 aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct gcttatgaag
     4621 tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac aaaatgaatt
     4681 gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga caagctcttt
     4741 ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat acagggaata
     4801 cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag aagttgtatc
     4861 gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc tcttatactt
     4921 actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa gagcagatcg
     4981 aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg atgtcttcaa
     5041 gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt atagatgcta
     5101 tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt ccacaaatca
     5161 gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca gcgtatgcat
     5221 ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat acagattgaa
     5281 taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag ttctttagcg
     5341 aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt aacattttcg
     5401 gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac cgatttgcag
     5461 aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc caatagatcc
     5521 aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc atcatcgtat
     5581 gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc tacttgggta
     5641 cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac aatatcggcg
     5701 atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc catgatgtgc
     5761 ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt gaaaagaaaa
     5821 taaaacctaa agacacctgg ggaatgtcat ttggctaaat gtatgccgct atgttaaaat
     5881 gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc acgtgaaatt
     5941 gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct gcgtgatttt
     6001 ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta tatcgagagt
     6061 catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac ttgtatcagt
     6121 ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa cggtgatttg
     6181 gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg ttgggcctat
     6241 gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa gaaagctttg
     6301 tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg tcatgctatc
     6361 caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg tcatggcgtt
     6421 ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg aaaagggttg
     6481 cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg aacttggaaa
     6541 atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact ttcttgccaa
     6601 tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc acaaggagaa
     6661 gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga aagtttggaa
     6721 caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa agcgcatcac
     6781 tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct tgtctttatt
     6841 tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc aagagactgt
     6901 actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg gtcctgcaat
     6961 caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat tagcggcttt
     7021 atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag cgtatggcgt
     7081 agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca ttgtcttgtt
     7141 catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga ttttggatgc
     7201 tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa ctttgaagtg
     7261 gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa ttgtccctaa
     7321 tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg tcggctggat
     7381 gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga tcagcggtta
     7441 tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg ctacgatcat
     7501 cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc atcaaatcaa
     7561 aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat tttctcataa
     7621 aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat aataattatg
     7681 actcttaatt aaagtaggtg cccatatgct tgtttctttt agtatggtta taagattttt
     7741 tctgacaatt ttattatcac tgatattaac acctgtattc aaaatcattt cagtacaaac
     7801 aggtatggtc gacaaaccaa atgaaagaag aataaataaa gttccaatgc cttcagcggg
     7861 cggactgcct atctttattt catttgttat atcgacttta ttcttattcc gtaaaattat
     7921 ccctcaatcg tatattgtac cgatcttgat tgcttcttta gtaatcatag tcacaggagt
     7981 gctcgatgat aaatatgagc tgacacctaa acaaaaaagt atagggatct tgattgcttc
     8041 tcttattatt tattttgtag cagatatacg tattgattcc ttcacgcttc cttttattgg
     8101 atatatccaa ctaggctggc ttagttttcc cgtaacgatt ttttggatct tcggtatcac
     8161 gaatgcggtc aatctgattg acggtttgga tgggctggcg gcagggattt cattgatcgg
     8221 tttaattacg ataggaatca ttggatattt tttcctccat gcttctacag tgtatattcc
     8281 agttgttatt ttctgtcttg tagcaagtat tatcggtttt tttccttaca atttttatcc
     8341 ggcaaagatt tatttaggcg atacaggagc tctattccta gggtttatga tggccgtcct
     8401 ttcactacaa gggctgaaga acgtgacttt tgtttcatcg atttctttgc tgatcgtcat
     8461 gggagtgccg gtaacagaca cgttttttgc tatcattagg agaaaagcaa accgtgtttc
     8521 tttttctaca gcagataaaa aacatcttca tcaccgacta atcagtttag gctttactca
     8581 taaaggtgct gtcctgacga tttatgcgat ggctttgatg ttttctttca cagctatggt
     8641 catgaattat actggaagaa tcggaacgat catattgatt attgccatgt tgtttgctgc
     8701 aattttatta tttgaattga ttggtctgat caatgagaaa catcagttta ttttaaaaac
     8761 attgcgattt ttagggaata aagagtaccg tacgcaagta aaacagaaat atttgaagaa
     8821 atggaaccgt catatagatg aataacaaat taaaccagcc gatccttatt agtattgtga
     8881 cggcaaacag tgataaaatt tttcggacac tagataattt tatttcaact gtaaaagatg
     8941 aaacagcagt aaaaatccga atttttgaca acaattcact tcccgagtac aaaaaaagac
     9001 taacagagta taggaaatat ccctacatcg atatctattt tcatgatgaa aattccggat
     9061 ttggttatgg acataatcac aatctgatag ctagcgattc tcgctatggc attatttgta
     9121 acccagatat tttagtggat gaagagacag ttacagcatt ggtcttgtta ttgaaagaac
     9181 atccggaatg tgcgatgtta gcacctaaga ttcttaatga agatggaaca actcagcacc
     9241 tcatccgtga gcagctggct gtttttgatt acgttttgcg ctttgtgcct ttcaaatggg
     9301 tcaaaaaaaa gtttgacaaa cgactggctg tgtttgaatg ccgaggattg cctactgatg
     9361 ctaatagtta tgtacggatg atctcaggta gttttatggt agctgatatt gataaattta
     9421 aagagataaa ggggtttgat gagcgtttct tcatgtactt tgaagacaac gacttgtgtt
     9481 tgagttttga aaaagcaggt tacaagttat tgtacacacc cttttatgca gttatccatt
     9541 tttacgggaa gggtgcgcat cgaaatgcaa aactgtttcg cgtgtttttg acttctatga
     9601 tgaaattttt caataagtgg gggtggcgtt ttttctgatg aaaccagaaa tattagtagt
     9661 cgttgtgctt tatcagcaac tattcagtca atctccagct tatggaccat taagcaaagc
     9721 acttagcgaa aagcaaattc agcttattat ttacgataat agtcctcaaa ggcagcaaaa
     9781 tgagctgttt gaaaaagaaa atatcgttta tcatcatgat ccgcaaaatc ctggtttagc
     9841 ggtggcttat aattttgcgt tgtctcaagc agatgaagga acacgttgtc tcgtcactct
     9901 ggatcaggat acgaggctag tcgacgatta ttttgaacta ttgcgtaaag taacctttac
     9961 agatgaatgt gttgctgcag ttccgatgat tttttctggg agccgacaag tttctcccct
    10021 atattcagat cgttatatca atcgtacagc tcaagcagta gaagttgaag gcccaacagc
    10081 tgaacgaatc atggcaatca attcaggtgt tgcctggtct gtcaaatttc taaaaaagat
    10141 tggcgggttt aatcctgctt tttctttaga ttttttggat cattggctgt tttggaaagt
    10201 ggatcagttg gaaaaaactg tggagatcct tcctgtacga atggaacatg atctttcggt
    10261 tttagactat gaaaaagttt caagtaatcg ataccgttct attttacaag cagaaaatcg
    10321 attttatcat gaatatgatc aaaggcattt atccagtcac cgacgacaat tattgttaag
    10381 aacagctaaa cagttcttga ccgtcaaaaa ccggcatatc tggcggatga ctttgcgctc
    10441 atatgttaag aattggaagg tgtgaattcg tgcgttcggt ttgtatagct acctttaatg
    10501 gaggcagata tttaagagag cagttagata gtattttatc tcagctttca gcagaagatg
    10561 aagtagtcat ttctgatgat gggtcagtag atgatacatg ggatatatta actgaatacg
    10621 cagaaaaaga taagcgaatc cagctttttt cggggcctcg tcaaggattg atcgctaatt
    10681 ttggttatgc gatccagcag acgaaaggag atctaatctt tttggcagac caagatgatg
    10741 tttggttgga gacaaaagtg aaaaagatca ctgactattt tgagcagaat ccggatcagc
    10801 tagtagtagt ttctgattta atcattgtgg acagcgagct gcaagagatc catgattcgt
    10861 atttttcgtt tcgaaattcc aaagaaggat ggcttaataa tgtgataaga agtcactata
    10921 ttggtgctgg tatggctttc cggtcttctt taaaacccga tattttgccg atcccgtcag
    10981 aagtgccgat gcatgatatg tggattggtt tgctgggagg aaagaagact gggttcctaa
    11041 gagaaccgtt aactctgtac cgaagacatg atttaaacgc gagtgagatt gaaacacatt
    11101 ctaaattacg gcaaaaaatt tcttggcgtg ttcatctgat tacggcgttg atcaaacgaa
    11161 aatggtttaa acgttgataa aagatgttta aatccttaat atttccatga caaatataac
    11221 aattgatgag ataataacaa agtgaaattt gaaatcaaaa aggagagcag atatccatga
    11281 agggaatcat tcttgctggg ggcagcggaa cacgtctgta ccctttaaca aaggcaacat
    11341 cgaaacaatt gatgccgatt tatgacaaac caatgattta ttatccaatg tctactctga
    11401 tgttggcggg aatcaaagaa attctgatta tttcaacgcc acaagataca ccacgtttca
    11461 aggaattatt tggaaacgga aatgatttag gactgcagat cgaatatgca gtacaagaaa
    11521 gtccagatgg attggcacaa gcgtttatca ttggagaaga atttattgga gatgatagtg
    11581 tctgcttggt attaggggac aatatttact atggtggcgg tctgtctaaa atgttgcaac
    11641 gagcagcttc aaaagataca ggcgcgacag tatttggcta tcatgtcaat gatccagaac
    11701 gctttggtgt agtagaattt gatgagaata tgcaagcttt gtcgattgaa gaaaagcctg
    11761 ctcagccaaa atcaaattac gctgtaactg gcctttattt ttatgacaat gaggtaattt
    11821 ctatcgctaa aggtatcaaa ccttcagaac gtggagaact agagattacg gatgtcaata
    11881 aagcatattt ggataaagga aaactatccg tagaacttat gggacgcgga tttgcttggc
    11941 ttgatacagg aacacatgaa tcattgcttg aagcatctac ctttatcgaa acaattgaaa
    12001 aacgtcagaa cttaaaagtg gcttgtttgg aagaaattgc ttaccgtatg ggctacatcg
    12061 ataaggaaca attgctggcc cttgcacagc cattgaaaaa aaatcaatac ggtcaatatt
    12121 tattgaattt ggccgctgaa taaggagtcc ttacagatga aagtaacaga tacaaaatta
    12181 acagatgtca aaatcgtaga aatggacgtc tttggcgatc atcgcggttt cttcacagaa
    12241 agttattcaa aagcaaaatt tgcagaacat ggattgaaat atgactttgt tcaagacaac
    12301 cattcactat cagctgaagc tggtgtcctt cgggggcttc atttccaaaa aggagaagct
    12361 gcacagacaa aattgattcg ggtagtcact ggagcagttt tagatgtagt agtggatatc
    12421 cgcaaaggta gcccgactta tggtcaatgg gacggattta tcttatctga acataatcat
    12481 cgacagttgc ttgtacctaa aggatatgcc catggattcg ttactttgac accaaatgtg
    12541 aacttccttt ataagtgtga taattactat aatgcagaag cagatggggg catcgcattt
    12601 gatgatccag atttagcgat tgattggcca attgatccat caagagcgat tatgtcggaa
    12661 aaagatcacc gtcatccgac attaaaagaa tttgaagcag aaaatccatt tgtttacgga
    12721 gaaatctaag aattaaggag aaattttctt atgaaaaaca tcattgttac cggaggtgcc
    12781 ggattcatcg gctctaattt cgttcattac gtggtaaaca atcatccaga agtgcatgtc
    12841 actgttttgg ataaactgac ttatgcagga aacaaagaga acttggccgg acttcctagc
    12901 gatcgcgtag aattggtcgt aggagatgtt gcagatgcag aattagtgga ccgtctagta
    12961 aaagaagcgg acgcagttgt tcattacgcg gcagaatccc ataacgataa ttcattaaaa
    13021 gatcctttcc catttgtaca aacgaatatc attggtacgt atacactttt agaagcttgc
    13081 cgcaagtatg atgtacgcta tcatcacgta tctactgacg aggtttacgg cgatcttcca
    13141 ttacgtgaag acctgccagg acatggggaa ggcgaaggag aaaaattcac tgcggaaaca
    13201 ccatataatc cttcaagtcc atattcttct acaaaagctg gttcagatct gttagtaaaa
    13261 gcatgggtgc gttcttttgg cttacgtgca accatttcaa actgttcaaa caactatggt
    13321 ccttatcagc atattgaaaa atttattcct cgccaagtaa cgagtatctt aagcggtatt
    13381 cgtccaaaat tatatggcga aggaaagaat gttcgtgact ggatccatac gaatgatcat
    13441 tcttcagcag tgtggctgat tttgacgaaa ggcagaattg gcgaaaccta tctgatcggt
    13501 gcagacggtg aagaagataa taagaccgtg atggaattga tcttagaaat gatgggccaa
    13561 ccaaaagacg catacgacca tgtaaacgac cgcgcagggc acgatttgcg ttatgcaatc
    13621 gattcgacaa aattgcgaga agagctaggt tggcagcctg agtttacgaa cttccgtgat
    13681 gggttggctg acacgatcaa atggtacgaa gaacatgaag actggtggaa aaaagaaaaa
    13741 gaggccgttg aagcagcata tgccaaaaat ggacaataat acagaggaaa tttcactgta
    13801 ttaatggaaa aacacatgtg aggcaggcgc tcgcctgtct cttttttaaa ataaaaatca
    13861 aggagcggat aaccatatgt ttttattaac tggaggaaat ggacaattag gtacagaatt
    13921 gcgccattta ttagatgaaa aaaatctgcc atatgtttca acagatgcaa aagacttgga
    13981 tatcacagat gctgagaaaa caatggctta tattacagaa ttaaaacccg atgttatttt
    14041 ccattgcgca gcttacacag cagtagataa agcagaagaa gaagcaaaag aattagatga
    14101 gaaaatcaat gtcgatggca caagaaatgt agcacttgca gcaaaagctg tgaatgcaca
    14161 attcgtctat atcagtacag actatgtttt cgatggaaaa aacaaaaatg tagaatacga
    14221 agtagacgac caaacgaatc cactaaatga atatggtcgt acgaaattat taggcgaaaa
    14281 agcagtagaa gagattttag aagactatta tatcatacga acttcttggg ttttcgggat
    14341 ctatggacac aatttcgtct tcacgatgca acgcctagcg gaaacccgcg acaaactgac
    14401 tgtagtaaat gaccagtttg ggcgaccaac ttggacacgt actttggcag aatttatggt
    14461 atatgtcatc gaagaaaaag caccatttgg tatttatcat ttgtcgaacg aaaatagctg
    14521 ttcttggtat gagttcgcaa aagaaatatt gaaagataca gatgtagaag ttgcacctgt
    14581 tacgtcagaa gaatttccgc aaaaagcaac acgtccgcag tattcagtca tgagcctgaa
    14641 aaagacagaa gcgttaggtt ttgtcatacc aacttggcaa gaagcacttg cgcaaatgct
    14701 ggaagctgcc aaaaaaatga ataagtaatt tcctttttat caaatagaat ttggagcatg
    14761 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aatcaggcag
    14821 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    14881 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    14941 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    15001 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttt
    15061 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    15121 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    15181 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    15241 tcgaagtact gatgatatta acgaagagga aaaaagctct atcgctaatc ggtgcatttg
    15301 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    15361 tctttacttt gggactgatg attacttttt atcattattt ctacaatcat gataaaaaat
    15421 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    15481 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    15541 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    15601 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    15661 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    15721 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    15781 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    15841 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    15901 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    15961 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    16021 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    16081 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    16141 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    16201 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gtcgccttag
    16261 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    16321 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    16381 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    16441 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    16501 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    16561 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    16621 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    16681 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    16741 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    16801 ctagctgaga ataatcctga aatattagta gaaaggagag tgaagataat tcaagcaatc
    16861 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttgct gacgctagtc
    16921 ttttttgttt ggacagcagg ggtaggtttt ccagcaactt tgtttatata taacaatagt
    16981 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    17041 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    17101 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    17161 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    17221 tttacggtct tcctcggaat cacgttatat cgtgtattta cagagatcca agtaccagaa
    17281 ggacaaagca tctgggctcc aggcaattcg ctttctgata tttggatcaa tacgaataca
    17341 atcggaagtt ctttgatgac tcttgcttta ttgatcagtg gatttgccag ttcttttgaa
    17401 cgatggtatg ttcgaatcat cggtgggata gcagtcgttg cagccttttt aggtatttgg
    17461 gtctgccaat ctagaggtgc attagtcgcg ttgattgttt ttgcgatatt ggatctttta
    17521 cctaaatcgt tgatgcgtgt cattcgtgcg ccatttattg cctacacggt tacgattctt
    17581 ttagctttgc cgatttctta tctggcggct gtctctgaaa aagtcaattt gtttaccggt
    17641 cgagaagata tttggcataa attctatcag acgctaggag aaaaatctga acaagtttta
    17701 ctaggaatga aaacatttat cttccagcga ggaaaccaat ttttaggaaa ccacaatagt
    17761 tataattcta ttttgaatat ctatggattg ataggatttg ggattgctgc tttgctgctt
    17821 atccttttta ttggtcgctt aacgttgaaa gcagatttat ccaacgggca gatgactttt
    17881 atctgggcct tttttgcggt gatgatgcag tcatttatgg aggatacatt gacttcatac
    17941 cgatgggttc cgattattta tatcctgttg gctatggccg ttcatcgata tgatgaacca
    18001 gaagttacgg aggaattcta tgttatggaa gaggcatatg acgatatgac ttatgatgat
    18061 acatcttatg aggaacaacc agatagcgct cattcttcca ggatccaacg ctatcattga
    18121 taggcacaaa atacgagaga ggctgtgaca accgtcgcag ccttttttgg tttattgcaa
    18181 ttgtctagca tcttctgtaa aatagaaacg ttagagaaaa tcttgtatca tagaaaatta
    18241 agaaagaaat aagaacgcag ctcggtacca aaaatatggt aaaatggcac ttgactgtaa
    18301 ttcactgaaa atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaagg
    18361 acatttatca gaacagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat
    18421 atgcaggatc gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga
    18481 tttattggct ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat
    18541 ttatcgtata tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat
    18601 caactacggt tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc
    18661 gtatcttgcc cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga
    18721 ttggcatagc tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga
    18781 tttattattt attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga
    18841 tccaaccatt tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt
    18901 ggacattacc gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga
    18961 aattaaatcc gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt
    19021 ggttctggga gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg
    19081 taatcggctc tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag
    19141 aatagctatg acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta
    19201 cgcaaaacct tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga
    19261 tgtattttat gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt
    19321 cgtgggagaa aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac
    19381 accaacatcc ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc
    19441 aggattcaat cctgagtatt ctggctatga aaatatctat ttaaatggaa tggttctagg
    19501 attttcaaga gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgacatcgg
    19561 cgaccatatt tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt
    19621 tgctgtagcg atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg
    19681 agatcttgaa tttcaactaa aatgtatgga aaaatttaca gaaatcaaga actcgggaaa
    19741 gacgatttta ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta
    19801 ttggttgaaa aatggaaaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta
    19861 cgaaaacttt ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga
    19921 acgcttcgca gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaagataa
    19981 aaatccagtg gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt
    20041 aaaagacgat acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt
    20101 ttatgtgtgc ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga
    20161 gaatatcttt tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga
    20221 cgttgcggtc tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa
    20281 cttgtttgtc agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga
    20341 agaagggact catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg
    20401 tgggaaaaat tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcctggaa
    20461 acggccgatt aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgtcgagc
    20521 tagataagga attgttcgat tttgtcagcg agtttgccca agatggattt tatggagata
    20581 tcgaaagttt tgaatgggca aactattatg ctggacaaac atttgattac gttttgtttg
    20641 ccgatgtttt agaacatttg gtagatcctg gaaaaacgtt gaagaaagtt agagaatttt
    20701 tgaatgaaga aggagaaatt ctaattacat tccctaacct tgcgcataat tctgtcatga
    20761 ttgatttgtt caataatcaa ttgccatggg cttcttatgg tttgctagat gaaacccata
    20821 attcttttta tactcatgat ggcttccaaa aagtttttga aaaagcagga ttatacatca
    20881 atattgaaga ttatttgtac ttagctgtag gtgatacaga attaaaatca acttatgaag
    20941 aattgccgga agctgtacgt tatgatttca aaatgcgacc atttggcgaa gtctaccaat
    21001 acttcttctc attgatgaaa catccagtag cacaaagttc cattgcgcag ccgcaaaatt
    21061 ctaattatgt gaaagtatta gaagtaatcc agcaaacgaa acaagatgaa ataattcaac
    21121 aaataccatt caataatttc acaggggaaa atgagacact aagtttccat gtatcagaat
    21181 tagcagaacg aatggtgttt cgcttcgcgc agcaacctag ctttatcgaa ttcagcgcag
    21241 aagctgctgg agaaaaactc acatttatcg attcaaatgc tgtagtcaaa acagtaaatg
    21301 attgttattt gtttgatggt aaagatttac cagagttctt tttaacggat attgcaggga
    21361 aagaagtgac tatccattgt cactatcgtt ttatcggaga attgacacca acaatgaaag
    21421 aattgctgga aacaatccgt ccaatggctg aagttacaaa gcagctttct gagaaaaatg
    21481 atgaattaga aagagaaaat cattatctta ttgagaataa tacaagatta gatcagacgt
    21541 tgaaaacaac cataaatcgc tattgcacgt tgttggaaag tgatgaatgg acaatcaaac
    21601 atagattagg gcgacgtaag aaagaaacat cgaaaaaaat ccaagaaaaa gagctttctc
    21661 tatgtattga cgaaaaaatc tgggatgcag aaacaaagat attgaaaatc atcgggtggg
    21721 gaatcgctaa ttcggatcgc caaccattgt cctataagtt atcagccgac caatcaccat
    21781 tttttgaagc aattcctgtt ttacgagaag aagtcaatca agcaaaacag ctagctgaag
    21841 gagcaaaagc aggatttgaa ctgcggatcc tttgcgagaa ggaacgttca ttcttagttg
    21901 aagcagtggc tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat
    21961 aaagataagg agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat
    22021 cactcgtgaa cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac
    22081 caaagaaatc cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt
    22141 cgtaagattg gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa
    22201 ggtacgttta tcagggaaaa tgagaggaaa agcaatctta gacttccaaa cagcaagaca
    22261 tcaaaatggc atagctgtga aattaaacgg taaatatcct tatgatgacg gcattgaatc
    22321 ttcatgggaa agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg
    22381 cgtaaaaaaa gcaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc
    22441 agagtggatc agtcgtcatg agaaacctga tctgaaagag caaaggaaag aagtacaagg
    22501 atttgcctac cgcccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg
    22561 gctcgaaaaa tgcattgatt cggtacttga tcaaacgtat gatcactggg aactatgtat
    22621 cagtgatgat gcttctactg atccagctat ccgaaagtgt ctagaatcct atcaagcaaa
    22681 agatgataga attaaagtcg ttttccgaca agaaaatgga cacatcagcc tggcaactaa
    22741 ttctgcattg gaaatggcag aaggagagtt tatagcgctc ttagataatg atgacgaatt
    22801 acctccattt gccttatatg aagtggcaaa agtgctaaac gtacatccag aactggattt
    22861 gatctacagt gacgaagata aaatcgatgc agatgggaat cgctttgacc cgcacttcaa
    22921 agcagactgg tctcccgata cattgatggg aaataattat atctctcact taggcgtata
    22981 tcggacaagc attgttaagg aacttggcgg tttccgtaaa ggatatgaag gctctcaaga
    23041 ttatgatttg gttcttcgtg tgacagaaca aattcctgca gaacacattt accacattga
    23101 ccgtgtcttg tatcattggc ggacgatccc gggatcaact gcaagcaatg gagaagctaa
    23161 aagctacatc tatgattctg gagtgaaagc attgacagat gctctatcta gaagaaatat
    23221 caagggaagc gtacatcctg gcagaatttc tggtttttat gaaatcactt atgatgtttt
    23281 gcaagaagac ttggtcagtg tgatcattcc aactaagaat ggctatgaag atctaaaaac
    23341 ttgtgtggat tcgatcatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga
    23401 taatggaagt acagatccta aaatgcaaga attatttgca gaatacaagc atcagctgaa
    23461 agaccgattt atcgtcgaat taattgacat tccattcaat tattcacgta tcaacaatct
    23521 ggcagcagaa aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat
    23581 tgaacctgac tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt
    23641 aggagcaaaa ctgttttatc cagatgatac aacgcagcat gcaggagtat tattaggaat
    23701 cggtggtgtt gcagggcatg cattgaataa ctatgatcga acacattgtg gttatttcgg
    23761 ccgattggtc attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc
    23821 agctgacttc aatgctgtta acgggtttga tgaaacatta gaagtagcat tcaacgatgt
    23881 tgacttgtgc ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga
    23941 attgtaccat ttcgaatcta aatcaagagg ttatgaagat actccagaaa aacaaagacg
    24001 ttttgctggt gaaatcaaaa aaatgcaaga taaatggcca gcatatattg cgcatgatcc
    24061 attttacaat gataatttaa caaaagaagg aatcggcgac ttttcgttga gaccagatta
    24121 aactataata aaaagctgtt atgttgtgat tcgctcgcac ataacggctt tttatagttt
    24181 tttgtcaaaa aaaggcagaa ggtgccgact caaaaaaata agtcgaggtt gggacagaag
    24241 tgtttaactc cgagaaataa gaagaaattc acgaaaattg cttttcaaat ttttgtgaat
    24301 ttcggcttat ttaagaagaa gttgcttctg ctcccaccgt ttattcgttt ttaaagaatg
    24361 agacaaaagt gtttcttact tttgtcccac gctcttattc atgctcagag cgccaataga
    24421 tacaaaatca tagccaaagt ttcacgaacc ctagctgtca aagaatcgat attttatttt
    24481 aatataggct attttaaaat aaatggttta aggtattcct ctacaaaagc cactctatca
    24541 attatcatgg gtttaaaata agaagtgatg gagataacca gattgttctt agcgtcaata
    24601 taaagaacat ttccactatt accaattgct gaatatattt cgttctcaga atctaatacc
    24661 caccataaat agccatatct catattttgt aagtcttcta aagcactggt tctaggtttg
    24721 aacatctcgt ttatccacat gggtggtacg atttgttttc ctttatacat ccctttattt
    24781 aggcataata caccaatttt tgccagatca cttgccgata aacacaaacc atatcctgcc
    24841 gtcccgatat ttagtggatc acaaaaccag acattggttt taggagactt atccattgta
    24901 aactgcttat gttcttcagc tgtttcagca taataattga catggtttgg tatccctata
    24961 ggatcaaata gatacttatt ggcaaaatca acagttgtta gcttacttgt ctgatacaac
    25021 aagccagtta atatgtgtaa acagacagtt tgatagttga attcgccggt tatacctttt
    25081 cttcctccca ataaatctag tgatgttttt gtccaatctt cacttgaaca gacttttgtc
    25141 catggatcgc ctttacattt gtagggtgct ttcattgtta gcaagtgctt gattgtaata
    25201 gcgtaaatag ttttctcccc gcgtttcact ttatactctg gaaaataatc taatacttta
    25261 tcatcgatac ttttgattaa tccttgctct aaagcaatgc caatcagcaa agatacaata
    25321 cttttcgttg ctgacatgat atgacaagta tcgtcttttt tataaccatt ccattcatct
    25381 gtataaactt ctaccccatc cttatatgcg acaatttgac atatatttgg ttgtcgaaaa
    25441 ccaataaaat catgcaactc ttgtttattc ataagatatt acctcacttt cttctataag
    25501 cataatgtca ttaaaaatcg atttcaattt tttcgattct tcacgtaata caggtattct
    25561 tatggactag acagcgcttt gggaagatgg attctctgaa aaatataaag gttcacttta
    25621 tgagtggata aaaaaagcag caaatacttc gacttcttta atttaccaac attagtgaaa
    25681 atcgattcat ctggagattt gtaatttaga gtccttgtct tgattagagg tgtataaagc
    25741 tttttattag acatttttaa attccattac aatttgctta taaactaggt ttttaaaggt
    25801 gactatggta agataataga gatattattt tgtgattagg agtgtatata tgaataaaaa
    25861 tggagaatgg agtgctgcac gacggatatt cattatatta atggatgtta ttgtatacaa
    25921 tgcagcaata tatagtagtt tcttactgaa gtttcgtgga gagatcccat tacgaaattt
    25981 agaaactttc caacactcag caattattat ttcagtgatt tttattgcgt tgaacatttt
    26041 gttgggtgca tatgtttttt ataatcgaat gatcagtgac atcgtgtttg tcacagtcat
    26101 cggtcaggta ttgatgacac tagggatcat ggtagtgact tttgcgggcc gctggtttgc
    26161 ttttccacgt cttgttatct tactttcatt tgttctcggt acgcttttct taagtatcta
    26221 tcgtattctc gtatataaac tttatttacg cgtaagtcga gataaaaagg tcgtcattat
    26281 tgggttagaa aaggatgtcg caccagcaat ccaaaatttt ggttcaaaga aaaacaacaa
    26341 acataaagtc gaagcagtca ttcttgataa ctattatgca aacatcaaaa atatgattaa
    26401 agacatcgat attgtctatc ttgcttctca tatcgaagaa actgaaaaaa tcaaaatcta
    26461 tcaattagtt actaaaaatg aaaaaaaatt gtttttgaat acaacatttg aaaacttgac
    26521 attgatcaat ccaaatatta tgaatttcga agatgaaagt attattgaag catctggatt
    26581 tagaatccaa cctgaatatg aactattcaa acgtttgttt gatatcatcg tttcacttgt
    26641 tttattagtt attgcttcac catttatgtt attcacagca attttagtca aagtgacatc
    26701 accgggacca atcatctata aacaagtgcg gatcacaaaa aatcaaaagg aattttcaat
    26761 ctataaattc cgctcgatga ccgccacagc cgaagcaaaa tctggaccag ttttagctaa
    26821 gagcaatgat gcacgagtaa cgcctgtagg taaatttatt cgagctgtcc gctttgatga
    26881 attaccacaa atcttcaatg tgctgaaagg cgatatgtcg atcgtaggac cacgtcctga
    26941 acgtcctttc ttcgtcgatc agttcaatgc agaaaaccct tattactact tacggcataa
    27001 tgttcgtgct ggtatcactg ggtatgcaca agtctatgga aaatatgtct ctgattacaa
    27061 cagtaaatta cgttttgatt tactttatat caaaaaatat tcattgatgc ttgatttaaa
    27121 gatcttgctg caaaccatca agatcctatt tgataaaatg tcctctcaag gacttgaaga
    27181 agacgaaaat gtgatctcat tggcagaaat tgcttttccg aatgaaaaaa tctttcgcta
    27241 gttgggaggc gtaaaaatga acaatccgaa attcagcata atcgtaccag tatacaatgc
    27301 agaagcaact attggtcgaa agattgatat tctaaaagaa ttggattatg aagagtacga
    27361 agtcgtttta gtaaatgatg gatcaacaga tcaaacacag gaaatcattc aagaactgat
    27421 tgaaaatgat gaacgttttg aattgattac tacgaccaat caagggcccg gattagcaag
    27481 aaacgaagga ataagacagt caaaaggaga atatctctta ttcttcgatg cagatgacac
    27541 gccagtaaaa acgatcttgt cagattatga tcatttgcta gaaaagagtc caaaagcgga
    27601 tcttgttgtt agttcgtttg tttttcgtac aatggacgag ggaagaatcg tttccgaaaa
    27661 agaaaactta gttacagaat gtcactatct aactcacgaa gagtttataa aagacatgta
    27721 tcagttaatg aatgaacagt tgatgtatgt tgtatggaac aaatgctatc gtagcgatat
    27781 tctgaaaaat aaccaaattc tatttaaaac ttataatagt tgtgaggatc gaatatttaa
    27841 cttacattat tatgaatact gtcatcaagt gatcatgaac ccaaaagtag aatatattta
    27901 tgaatttgaa ggtgggaagg ggatcactaa tcaataccga cctaacaagt tcgaaacatt
    27961 taaagaattc tattcattag caaatactgt aacagacgat attaataaag acggtatggc
    28021 ggcgcttctt ttaaaaggga caacttcagt tattttttct atttatagta cctctgcaag
    28081 aacttcaaaa gagaagaaag acgaagcaaa gcagatattg agtgatccag tgatccgaga
    28141 agccaagcaa attgctaaga cggattcttc agcaaaaaaa ataacaaagt tgctttacaa
    28201 tatgccagct ccactatttt tatctgctgt aaaagttgga agcttcgttg aagtgaaaat
    28261 gccagggtta atggctgctt tgaagcgagt atattagtta atggaggaaa atataatgaa
    28321 aagaattttg cattttcagg gacgaatggg tttaggtgga gcagagtctt tcatgatgaa
    28381 tttatatcgt aaaattgatc gtacaaacta tcaatttgat tttttgattt atgaagatta
    28441 tgcagatgtt caagactatc attcagagat tgaaagatta ggaggccgta tttttgttgt
    28501 acctaatcct aagaaaaata tttttaaata tttaatagaa gtgaataagt tactaaaaaa
    28561 agaatctttt tctatagttc acaatcaggt ttattttggc gggggaatta atttatggtt
    28621 agccaaaaag aatggaatca gacagagaat tgctcatagc catgcaactg aagatggaaa
    28681 atctcaaaat attgtaatga atgtattgcg taaattttta accaaattgt tgttacaaaa
    28741 tgcaacagac taccttgccg ttagtcaaga agctggtgaa agtctgtttc aaaaccatcc
    28801 ctttgagata gttcataatg gtattgattt agagctttat agtaaaaatt cagaagctaa
    28861 ggttaataag agaaaagaat tggatatctc aatgagtact tttgttgtgg gaaacattgg
    28921 acgattagag aaacaaaaaa atcaatctta tttgttagag atttttttag aaatactaaa
    28981 aatgaattct gattcttact tgattttagt aggtgaaggg tcacttagaa ataaactgaa
    29041 agccaaagca gtagaattgg atatagagaa aagagtaaaa tttttaggag aaagaaacga
    29101 tattcccgag ttattatctg tgatggatgt ttttgtaatg ccttctcttt atgaaggtct
    29161 gccaatggtt ggattagaag cacaagcagc aaaattaaaa ttagtcttag cagatactat
    29221 ttccaaagat acaaagttaa caaataatgt ggattttgta tcattagatg aaacaccaca
    29281 agaatgggca aaaaaagtaa taaaagagcc gtatgctaat aaaataacac aagaactaaa
    29341 gagttatgat gtttcgtaca ctactgaaca aatggagagt atatatagta gagatcatta
    29401 aaaatgttca agatatttta ggagtgatta tttttgaaaa tatgttattt gatattggca
    29461 tacaatgata ttggcaactt aaagagattg gtcaatcgat tgaacgaaaa tgcagttttt
    29521 attattcata tagataaaaa aactgatata gaaccattta ttgaagcatt taaatcatat
    29581 gataatgttg aatttttatg taataaaaac cgtgttaaaa tttattgggg tggtttttcc
    29641 attgtacaag cagaaatcaa tttagtaaag agagcattac aaaatgagaa atatttaaaa
    29701 tatgtattat tatctggtgc tgattatcca atcaaagata atgagtatat ttataattat
    29761 tttaaaaaga atagttcagt ggagtttatt cgtggaatag atctagatca aattaaacat
    29821 aaagaatttt attataaaca tatagatgta tatcaaaaac atgattatcc tagaattaat
    29881 aggaataaca caactgcatt taaaattttt agagctataa ttaatcgttg tctgaggatg
    29941 attaaacttc ccccaaaaat tagacaccat aaatttgatt tgtatcatgg ttctcaatgg
    30001 tgggctttgt cgaaagaatg cctaacagaa ttaatacaaa tgtatgaaca aaatcaacaa
    30061 gactacctga attttaaaat aggtatgttt gccccagatg aaaaattttt tcatacactt
    30121 ttttttaatt cctcgttcaa aaataaaaat gttattggag gaccagattt accacttgaa
    30181 ttgaaaaata ttgaagaaac tactttacaa acttcgaaat tagcaaatat tcatattatt
    30241 gatccttcca tgaacaaatg gtttgatgaa agggatatag atcaaataaa agaaagtgaa
    30301 aaattatttg taagaaaagt taaatcggat tactctgata aactattaaa tagaattgat
    30361 aaagaaattt tgaaagttgg aaatatagat gaatagaata gtacctgttt tagagaagag
    30421 tttattaagt cgagatgcgt ttcgagtaat aaatttaatc atttgtctgc tttattttat
    30481 gcctagtact tttaatgtaa ctaatatccc gatgaaaata gcttttgctt ggggtggaat
    30541 tatagttttg tatgaggttt ttataaagaa aaattttttt aaaatgcgtt tttcttggct
    30601 actgattgga gcaatgatta gttttatctt aactataatc attaacagag aaaatttttt
    30661 aattccatct atttataatt ttggatattt gctgattact ttgatagtaa tttttcctgc
    30721 agacttttca caaagtgaag aggaaaaaaa gaaaaaaatg gtgtatttta ataatgtttt
    30781 cattatcata atttttttag ctgcgctaat atctatctat caatttattt ttttgatttc
    30841 ttatcatgtc ccaacaggaa cgccaggatt acttgcaaga caaggtttta ttgaacatcg
    30901 gttatttggt gtctatacaa gtccaaatgt tggagctatg tttggatata cttctattat
    30961 tttaagttta attagtgtat taatttcaaa aataacaaaa acgattcgtg ttttttatat
    31021 gatgaatttt atcgtacaaa tattttatat tacactttct tcgtctagag gtgcccaggt
    31081 agtaatttgt tcttttttag tattatttct tttgttgttt gccaattcaa aatttagaaa
    31141 gagcattaga gaagtactac ctgtaaaaat caaatggatg gtaagcatat tattagttct
    31201 attggtatat ttttcttttg gtactaatta tgctaaggat tttttagcaa caattcctgt
    31261 atcgattgat agaaaagtag aagttataga gtcaaatgaa tcagataaaa ctccacttcc
    31321 agaaaaagaa gtaatattac agcattctag tgataactcc gaaatttcag ctggtcgttt
    31381 tacgatttgg aaagctgcgc ttaaagttat aagaccaact ttgttatttg gttatggaga
    31441 gaccgatttc tatgggaata gcgatgcaaa atttttgaaa aaagtagatc ttgatactac
    31501 agatgtgaat gaactaaaaa gagcacatgg aaacatgcat aatggatttc ttcaagtact
    31561 tgtatcaagt ggtataattg cttttatatg tatctatgct ttctatgtgt taaatatctt
    31621 tagtttactc aaaacatttt ttagaagtaa agtgaattat gcgtttcttg gtattgtttt
    31681 aatttttata ctatctattt ttatagatga aatggtggag gctcatgtac ttttcaataa
    31741 gcgcgatgtc atttcaattg ttttctggta ttatttggga agcatttctt acttgtattt
    31801 aaaaaaggag aattaatatg aagacagctt tcattgcttg gactccttta catttgatta
    31861 atatattaaa tgtttatcaa aatttttacc gagaatcaaa aggagattta tttatttatt
    31921 ctgaatttga aaacgctaga agatatagtg agcgtataaa agaattaggg ctatttaatg
    31981 atgttgtttt tgtgaatcac cggaaaatcg gttcttcctt taaacgtaaa attaacttgt
    32041 taactaacca taatcaattt ttctcggatg atttatccgt ttatgatgaa atttttatac
    32101 agggggaaaa ttatttcaca aaaatacttt tctccaatgt ttacaaaaaa aatccagatg
    32161 taaaactaaa ttatatagaa gatggtttgg gtacttattt gaagaagagt atattttcaa
    32221 caagtaaaaa cgttcaaaga gtttttaaaa tattaaataa aaatagcatc ttcaaaaaaa
    32281 aaattgacga ttattttgtc tattgtccgg aattgttact ttatgatgta aaaaatataa
    32341 aaaaaattcc caaaatagat gaaaacagta aattgatgaa aaacatacaa tcaatctttg
    32401 ggatagaaga agtttttgtc ggagataaat gtatcttttt tgatcaacct ttattatctg
    32461 atggttatgg catagatgaa acagatattt tcgctaaagt aaatagtata ttttctggaa
    32521 aaaaagaaac tttaattaag cttcatccta gagcaaggac aaatcgttat ggtgaaaaaa
    32581 acatattgaa ttccagttta ccgtttgaag tcttgctact tgaaaatgac ttctcttcaa
    32641 cacttttgat tagtcctata tctacaattt ctttttcacc atctatgatg tttgaaaaga
    32701 cgatcaactc tattatgttg gctaaattaa ttttaaatga atatacagca ttatctgaag
    32761 ataaaaaaga aacattgaca aatattgttc ttttctgtga acattataac cgtctatcag
    32821 aagaaaaaat tttactccca gaaaactggg cagaattaag aaagttggta gagtatggga
    32881 ttatttaaca cactttccaa gtcaaaatta gttaagtcca gtttctggta tactataggg
    32941 aattttttta ttaagggaat ttcattcata actattccta tttttgtaaa tattactact
    33001 caagcagaat atggtttgat taataatttc acttcatttg tatcaatttt ttcgattctt
    33061 gttgggctaa gcctaaattc ggcaattaat aatgcaagtt ttgactataa agatgacata
    33121 aatgaattta tgtcatcggt actttctcta gctacacttt cgttaattgt gttcttatta
    33181 atagggaaca tatatttttt gttttcaaat gctttttttg atatgaacca acttgtattt
    33241 aatttgatgt tattacaaag ttttgctagt tttgtaatta gttatatcca gtcttatttt
    33301 acgattaact ttaaccattt taaatatttg attttatctt ttatatctac ttttttgaat
    33361 attgcaatct ctgtagcttt gatgcagaca ttatattttg atgataaata tgttggcaga
    33421 gtagtcggcg gaacactgtc atttgtgttg ataggtttag taatttattt aagaataatg
    33481 ataaagggtg ctcatttttt tgataaaaaa cagtggagat acgctttaaa aatctctttg
    33541 ccgctaatcc cacattcctt agcaaatata gttttagcac aattcgatag aattatgatt
    33601 aattcttatt taggtcctgc tgcgggggga atatattcct acattagtaa cataggtatt
    33661 attctaagcg taatatggat gtctactaat aacgcctggg ttccatggtt ctatggtgag
    33721 atgagtaaaa ataatgaaaa aaaagtgaag aaagttagta actattattt agtagtcttt
    33781 actttgatta cgatgattgt aatggtagtt tcgattgatt tagcaaaatt tatggctccg
    33841 aaagactatt attctgggtt atctttagtg gttccgataa ccttaggcta tttctttcag
    33901 tttttatata gtttaccagt taatgctgaa ttttatgaga aaaaaacatc gtttattgcg
    33961 attggtacag tagcaagtgc tatagttaat atactattaa acatgatttt catacctagg
    34021 ttaggaataa ttgctgctgg atacacaacc gtatttacgt attttttact ttttattttt
    34081 cattataata tcgctaaaaa aattacgaat aaacaattat ttgacacaaa aaaaatatgt
    34141 atcataataa tttttgtatc aattttttct ttgatacttc atattttaat caatcaaatg
    34201 ttgattcgtt acgttttgac atcattattg ataattagtt tagttatata ttttttaaag
    34261 attaagaatc gaattataga tgactataat tcataggagg agatataagt gtttaaagga
    34321 aaaacaatat tagtaactgg cggaactggt tccattggaa gtgaaattgt tcgtcagctt
    34381 ttaaaatatg aaccaaaagc tatcagaatt tatagtagag gtgaagaaaa acaattttat
    34441 atgcaacaag agctctcaaa tcacactaat ttgagatttt taattggtga tatcagagac
    34501 tctcaaagga ttgattatgc atgtcgtgat gtggatatta tttttcatgc tgccgcaatg
    34561 aaacacgttc cagcaagtga atataatcct atggaagctg taaaaacaaa tgtgatggga
    34621 actcaaaatg taatagatgc agcgatcaaa aataatgtaa aacattttgt aggtatcagt
    34681 acagataaag tagtgagtcc tactaacacc atgggtgcga caaagttatt gagtgaaaaa
    34741 ttaataatag ctgccaatca gtataaagga aaaacagaaa caatattttc ttgtgtaagg
    34801 tttggaaatg tcatggggtc aagtggatct gttattcctc tttttagtaa acaaataaaa
    34861 aacaataaag atattacttt gacagatgtt gatatgacac gatttatgat gtcaataccg
    34921 gatgctgcaa gattagttct gtctgctgct atgaattcaa aatttggaga aacatatgtc
    34981 ttaaaaatgc cggcaatcaa tattttaact ttagctcaat cattaataaa aatatataat
    35041 gatacacatg atgaaaaata tagaggtgaa ataaaagttg taggtatcag gccaggagaa
    35101 aaattatatg aagagctaat gactacagac gaaattgaac gctcatatga aaatgataaa
    35161 atgtatatca ttccaccaca ctatcatgct actgacgaac tgtacaaaga ttatgaaaaa
    35221 attaaaatca ctgcatactc ttcagatgca acagaattaa tgagtggaca ggaatttatt
    35281 agaatcgcaa aagagaataa tgtcgtgact tggtaaggag ttttatgatg aaatcagaag
    35341 tatatgtaat tgcagaaatt ggtgtaaacc ataatggaag tctagattta gctttagaaa
    35401 gtattgataa agctaaagaa tgtggagcta acgcggttaa atttcaaaca tttaaaacga
    35461 ataagctagt ttccaaaaag gctccaatgg caaaatatca gaaggataat cttaaagagg
    35521 acagttctca atttgaaatg ctaaaaaaat tagaattatc tcaatctgat tttattagaa
    35581 taaaagatta ttgtatacaa aataaaattg attttttgtc tactcctttt gatgaagaaa
    35641 gtgcagactt tctaaaacaa attggtgtac aaggatttaa aattggctca ggagatttaa
    35701 caaatttacc ttttcttaga aaaatagata tgtatgggtt gccagtttta ttatctacag
    35761 gtatggctga tattcatgag gtcagtgagg ctgtagattg tttcatagat agtccagtta
    35821 ctattttaca ttgtacttca aattatccgg ctagttctga agatattaat ttattggcga
    35881 ttaacacatt aaaagaaatg ttcgggatac ccgttgggta ctccgatcat tcattgggat
    35941 atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt aattgagaaa cattttacct
    36001 tggataagga actacctggt ccagatcata aagcttcttt agatcctcag gaatttgcag
    36061 attttgtaaa gcatattaga aacactgaaa tatttttagg tgatggtgtt aagcgagcaa
    36121 tgccttctga acttagtaca aaagaagtat caagaaaaag cctagtggtc actgagaatt
    36181 taaatgtggg agatattctt acagagaaat ctcttacaat aaaacgtcct ggaaatggaa
    36241 tagctcctaa gtttttatat caatatattg gcaaaaaagt taaaagacca ataagtgcag
    36301 atagtgttct gcttgaggaa gatgttgaat gaaaaaaata cttatagtaa gtggaacacg
    36361 agctgattat ggaatatata aacctgttgc tgagaattta ctacaagata attgggatgt
    36421 atcatttgtt gtttctggaa tgcatttatc ccataaatat ggatttacta aagaattgat
    36481 cttagctgac ggatttagaa ttagtggaga agttcaaagt ttgtttttag agaacaataa
    36541 gggaaacatg gctcggtctg tggcattaga gataaatggt ttcacaaata tatttgaaca
    36601 aactagccct gattttgtat tattactagg ggatagagga gaaatgttgg cagctgcgat
    36661 agcttgtttg tatcttggaa tcaaaacagc acatattcac ggaggcgaag tgtctggtac
    36721 tgtagatgaa tcaataagac atgccataac gaaaatagca tctgttcatt ttgctgctac
    36781 ggaaaaaagc aaagagcgtt taataaaaat gggggaagat tcttggagag tttttcccgt
    36841 cggagctcct agaatagata ctattttaaa taatagatta cctagtttta gagatataaa
    36901 agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt ttgcaagtat ttcatccagt
    36961 tgtaaccgaa ctagaaaata tagaaaaaca aattttagct ttgatcaatt caatggaaca
    37021 acaatctcaa ccaattattt gcattttacc taatagtgat gctggtagcg aaattatcag
    37081 aaaaatgtac cagaaatatt taaaaacgga tattatttat attacgaatt tagagccgga
    37141 ggaatacctg actatattaa aagagtgcaa atttatgatc ggaaattctt cttctgggat
    37201 aattgaagct gcatcattca aaataccagt aataaattta ggaaccagac aaaatggacg
    37261 agaacaatct aaaaatatta taaatgcaaa tctaaatgaa aatgaaattg aaactgcttt
    37321 gaataaaata caagatcctc agtttataaa aagcttgaaa aatgttaaga acatctacgg
    37381 tgacggcaac agttctagaa gaataacaaa aacattgaat caaatattga atgatgggga
    37441 agatattaag tggattcaaa aacaaatagc ttattaaaat atactagtga tccatacatt
    37501 attattgggg ctggcggaca cgcaaaagtc attattgaaa ccttaagatt agaaaataag
    37561 ttaatatatg gattttttga tgataagcaa aataaaatgc aagatctgaa atatcttggg
    37621 aaaataaacg aattgaatag ctgggcggat agcaaaaaaa aaatctataa atttattgta
    37681 gctattggtg actgtgtagt aagaaaaaag attataaaaa aattgaatat gccaagtgag
    37741 caatatggaa tagctgttca tccaagtgct atagtggcaa aagaaatttc aattggttat
    37801 ggaactgtta tttttgcgaa tgctgtaatt aacccagatg ctgtaattgg agagcatgct
    37861 ataataaaca caggtagcat tgttgagcat gattgtagaa ttaataacta tgttcattta
    37921 tctccaggtg tatgcttagc gggtggagta catgtaggtg taggaactca aataggaatt
    37981 ggttctcaat gtatccagat gaagaaaatt ggatcttggt gtatgatagg cgcagggagc
    38041 actattgtta aggatattcc ctcacattcc ttagcttatg gcaatccagc taaaattaag
    38101 aaagaaggaa ttaattttga attctagaat tttattatca agtcctcata tgggaggaac
    38161 agaagaaaaa tatgttgcta aggcttttaa agataattgg atagcgccat taggtgaaaa
    38221 tgtggataaa tttgaagaaa gtattacaaa atatactggt tctaagggcg gagcttctgc
    38281 gttaagttca ggtacagctg ccatacatct tgccttaaga ctgcttaatg ttggaaaaaa
    38341 cgatattgtc tttgctcctt catttacttt tatagctaca gtaaatccta ttttatatca
    38401 aggggctgta ccagtgttca ttgactcaga acctaataca tggaatatga gccctgttgc
    38461 actagagagc gcattagaag aagctgaaag aaacaaccaa ttacctaagg caatcatcgt
    38521 agtgaattta tatggtcaaa tggctgatta tgaacgaatt ttagctattg caaaccaatt
    38581 taatgttcca gtgatagaag atgcagcgga atcgttaggt tctacttata agggaatttc
    38641 gtcaggctta tttgggacaa ttgggatcta ttcatttaac ggtaataaga tcatcacaac
    38701 ctcaggtgga ggagctctag tgtctagtga taaaaaatat gttgagcatt caagattttt
    38761 agcaacacaa gcaagagatc aagcaccgta ttatcaacat agcgaaatag gttataatta
    38821 ccgtctaagc aatatttctg ccggtatcgg acgtggacaa atggaagtat tgaatgatag
    38881 agtagctaaa cgaagagaaa ttttcaatcg atataaggaa gctttttctg gaattgatag
    38941 aattgaaatg atgccagaag tggatggcat ggtgccaaat cgttggttgt ctactttaac
    39001 gatcaatgat tataattcta ttgatcaagt agttaacgta ataaataaac taaatgaaaa
    39061 aaacattgaa acaagagctt tgtggaaacc actacatttg caaccagtat ttcaaggggt
    39121 aaaaatgtat taccatgata ataatcttag tgtgtcagaa aagttattta atagcggctt
    39181 atgcttacct tctggaagta atatgacaga tagtgaacaa gaatttgtta ttgatgagtt
    39241 taaaaaaata ttcaagtagg tgtgatattt tatgaacata ggaattattg gtttaggttc
    39301 catggggaaa agaagactta gactcattca agaacacttt aatgatattt tactatgtgg
    39361 tgttgatact aatgaggcga gacgaaagga agttgaaaag gaatttggaa taccaactta
    39421 taatagtcta acagaggcaa aaaatttgtt tgaaataaat tcagtttttg tttgtacatc
    39481 ccctataacc catgaattta ttataaaaga ggctttaaat ttagattgta atatctttac
    39541 ggaaatcaat ttattaaatg aatattatga tgaaataatc gaagtagcta aaaagaaaga
    39601 tagattactt tatctatctt ctacattttt gaagagaaaa gaaattcaat atattaagtc
    39661 taaagtgacg cataataaaa aaatttctta tcaataccat gtaggacagt atttacccga
    39721 ctggcatcct tgggaagatt atcgcaattt ttttgtttca aacaaaaaaa ctaatgggtg
    39781 tagagaaata ttcgctattg aattaccttg gattatagat acatttggga aagttaaatc
    39841 gtttactgta atgacccaga aattatccaa tcttgatatt gattattcgg acagtttcac
    39901 tcttattatt gagcatgaaa ctggtatagt tggaacttta agtgtagatg ttgtttcaag
    39961 agtagctaaa agaaatttaa ctataattgg tgaaaagatt ttaatagaat gggaaggtaa
    40021 cccggattct ctattttcat ggaatgaaga aacttctagt atgacagata ttcaattgta
    40081 cgatgaggtt atgcatgata ataattattc acatactatt attgaagatg catatttaga
    40141 ggagattaaa gaatttttca cgcttttgga aaagaaaatg gaaccccaat atacttttga
    40201 aaaagataag tatattatta acttaattaa cgacattgag gtaaattaat gatgaaagta
    40261 attttttttg ggttagggtc aattggaaag agacatctaa aaaatctaat aagctatgga
    40321 aaaaagaatt ctattaattt tgatataaca gcttatagta gcagtggaaa aaaagagttt
    40381 gaagaaataa cgtatattca aaatagagac gatttggata cacattatga tatagctttt
    40441 attacaaatc cgacttttaa gcatctggaa acactaaatg taattgttga aaaagttgat
    40501 tacatatttt tagaaaaacc tgctttttct gagagtattg atcttactca atataattat
    40561 gattacaaaa atatttatgt tgctgctcca ctgaggtata aaaatatcat ggaagttgtt
    40621 cgtaatagta ttcaaagtaa aaaagtatat tctgtaagag ctatttgttc tacttatctt
    40681 cctgattgga gaaaaggtac tgattataga aataattatt ctgcctttaa atctatgggg
    40741 ggaggagtag aattagactg tatacatgaa ttggattata ttataaacct atttggtttc
    40801 cctaaatcag taaaaaaaca gtttggtaaa tattcgaatc ttgaaattaa cagtaatgat
    40861 ttagcaacat atatattgag atacgatgat aaaattatag aaattcattt agattatttt
    40921 ggaagagttc ctacaagaaa atttcaattg tttactttag atgaatgtat caatgttgac
    40981 ttattaaata ataaaataag ttttgaagaa aacattgtta aagaaatgcc tgaatctgct
    41041 aatgatatgt atgagaagga gttgaaatat ttctttgaaa acgtagtaac aggcaaagaa
    41101 aactggaatg atttatatca tgcaaacgaa gtattgaaaa tagctgagga gaaataaatg
    41161 gaaattttat ttactatttg tggtagagct gggtctaagg ggtttaaaaa taaaaatttg
    41221 aaatatttgg caggaaagcc cctagtccat ttcgctttag caatgataga tatctatcaa
    41281 caaaaacatc ctgaacataa ttgcacgact tgtttgaata cggacagtaa tgagttagta
    41341 gaattgacga ctaagttaaa tccgtctgtg aaaattgtag aacgtaaacc tgaattagct
    41401 acagatactg tagggaaaat tgaagtgata cgtgattcat tcttacaact agaaagagaa
    41461 gataatatat ttgatttaat tatagattta gatttgactt cacctttacg tgaagtttct
    41521 aatcttgaag aattaataga tgaacatcta aaaaatttag ataaagacgt ctacttttca
    41581 gttgtttctg caagacgtaa tccctatttt aatatggtaa aaagaattga aaatgaagtt
    41641 actatagtta ataaatcaag atacacatct aggcaacaga cacctgaagt ttttgaaatg
    41701 aatgcctcaa tgtattcttt taaacctgaa tttctaaaaa aaagtaatta tatttttgat
    41761 gggcaatgtg ggataataaa aatgagagat tatctaattt tagatattga tagtgaagaa
    41821 gattttaaat ggttagaatt tttgtttcct aaatttttag aagattcttc ggagcttcaa
    41881 gatatctata attatttata tcggaggtaa aaggatgagc tgttatctta tcaccggtgg
    41941 ggctggcttc attggttcta ccttagccaa tcatttagga gaagaacatg tggtaatcgt
    42001 cgtcgatgac ttatcaatgg gaaaagtaga aaatcttgat atgacgaaaa atatcacttt
    42061 tattgaggga gatgtcgctg agaaatcctt gatggaagag atcatgaaag ctaataaatt
    42121 tgattatatc tttcatttag cagcagttgc tagtgtggca gattcagttg cccgaccagt
    42181 agaaacacat cgtgtgaatt ttgaaagtgt attaatgatt ttagaattga tccgcaagta
    42241 tcaacctgat ttaaaacgga tcgtgtttag ttcttcagcg gctgtttatg gggatgaacc
    42301 gactttacca aaaaaagaag agtccgtgat tcgcccattg acgccttatg cggttgataa
    42361 attcgctgca gaacaatatg tgctagatta ttgtcattta tatgatgtac ccggtagcgc
    42421 agttcgtttt ttcaatgtct atggtccaaa tcaaaatccg aattctccat acagtggtgt
    42481 gatttctatt ctcgtagatc gctataagaa acaaatcgta ggagaagcaa cttcatttac
    42541 attatttggt gatggaagcc agtctagaga ctttgtttat atagatgatg taatccaagc
    42601 attactttta gttgcgaatg aggaagctgc actggggaaa caattcaatg ttggaacggg
    42661 taaagcaacc acacttttgg aattgattca tgcaatcaat gaaattctcg gtgtagaatt
    42721 gacacttgaa tacaaagaag agcgttcggg tgatatccat gactctctag cagatattac
    42781 taagatccag tcaattggct atcaaccgaa atatggtatt ttaagtggaa tgactaatta
    42841 tttgaaaact gaaatcaatt aaaacatact aagataagat tagagggtaa attcaggctc
    42901 tttgtcaata aggactgatg agttttgtaa aatcaaatct gggatagaa
//
LOCUS       DBGZHO010000016        40656 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.016, whole genome shotgun sequence.
ACCESSION   DBGZHO010000016 DBGZHO010000000
VERSION     DBGZHO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.016"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(61..2424)
                     /locus_tag="ACN3HL_001078"
     CDS             complement(61..2424)
                     /locus_tag="ACN3HL_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HHC8005969.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2589..3093
                     /locus_tag="ACN3HL_001079"
                     /pseudo
     CDS             2589..3093
                     /locus_tag="ACN3HL_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACN3HL_001080"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACN3HL_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HHC8005970.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACN3HL_001081"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACN3HL_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HHC8005971.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="ACN3HL_001082"
     CDS             complement(5894..6205)
                     /locus_tag="ACN3HL_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HHC8005972.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="ACN3HL_001083"
     CDS             complement(6202..6495)
                     /locus_tag="ACN3HL_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HHC8005973.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACN3HL_001084"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACN3HL_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HHC8005974.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACN3HL_001085"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACN3HL_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HHC8005975.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="ACN3HL_001086"
     CDS             complement(8333..12685)
                     /locus_tag="ACN3HL_001086"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HHC8005976.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="ACN3HL_001087"
     CDS             complement(12897..14606)
                     /locus_tag="ACN3HL_001087"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HHC8005977.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACN3HL_001088"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACN3HL_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HHC8005978.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="ACN3HL_001089"
     CDS             complement(16103..16903)
                     /locus_tag="ACN3HL_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HHC8005979.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="ACN3HL_001090"
     CDS             complement(16900..17712)
                     /locus_tag="ACN3HL_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HHC8005980.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACN3HL_001091"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACN3HL_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HHC8005981.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACN3HL_001092"
     CDS             complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACN3HL_001092"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HHC8005982.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACN3HL_001093"
     CDS             complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACN3HL_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HHC8005983.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACN3HL_001094"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACN3HL_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HHC8005984.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="ACN3HL_001095"
     CDS             21446..21925
                     /locus_tag="ACN3HL_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HHC8005985.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="ACN3HL_001096"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="ACN3HL_001096"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HHC8005986.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /gene="phnX"
                     /locus_tag="ACN3HL_001097"
     CDS             23226..24011
                     /gene="phnX"
                     /locus_tag="ACN3HL_001097"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HHC8005987.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACN3HL_001098"
     CDS             complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACN3HL_001098"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HHC8005988.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACN3HL_001099"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACN3HL_001099"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HHC8005989.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACN3HL_001100"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACN3HL_001100"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HHC8005990.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACN3HL_001101"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACN3HL_001101"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HHC8005991.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="ACN3HL_001102"
     CDS             30332..31033
                     /locus_tag="ACN3HL_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HHC8005992.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACN3HL_001103"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACN3HL_001103"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HHC8005993.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACN3HL_001104"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACN3HL_001104"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HHC8005994.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACN3HL_001105"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACN3HL_001105"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HHC8005995.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACN3HL_001106"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACN3HL_001106"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HHC8005996.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="ACN3HL_001107"
     CDS             complement(34528..35508)
                     /locus_tag="ACN3HL_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8005997.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACN3HL_001108"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACN3HL_001108"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HHC8005998.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACN3HL_001109"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACN3HL_001109"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HHC8005999.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="ACN3HL_001110"
     CDS             38266..38433
                     /locus_tag="ACN3HL_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HHC8006000.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="ACN3HL_001111"
     CDS             complement(38495..40306)
                     /locus_tag="ACN3HL_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HHC8006001.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..>40656)
                     /locus_tag="ACN3HL_001112"
     CDS             complement(40303..>40656)
                     /locus_tag="ACN3HL_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HHC8006002.1"
                     /translation="KRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIAPSNE
                     ARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKNEHQN
                     HAVLLKKFIEMEACK"
BASE COUNT        11050 a         8686 c         7200 g        13720 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttt
//
LOCUS       DBGZHO010000017        39679 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.017, whole genome shotgun sequence.
ACCESSION   DBGZHO010000017 DBGZHO010000000
VERSION     DBGZHO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.017"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(148..2301)
                     /locus_tag="ACN3HL_001113"
     CDS             complement(148..2301)
                     /locus_tag="ACN3HL_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HHC8006003.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2595..3443)
                     /locus_tag="ACN3HL_001114"
     CDS             complement(2595..3443)
                     /locus_tag="ACN3HL_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHC8006004.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="ACN3HL_001115"
     CDS             complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="ACN3HL_001115"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HHC8006005.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5944..6123)
                     /locus_tag="ACN3HL_001116"
     CDS             complement(5944..6123)
                     /locus_tag="ACN3HL_001116"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HHC8006006.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6170..7993)
                     /locus_tag="ACN3HL_001117"
     CDS             complement(6170..7993)
                     /locus_tag="ACN3HL_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHC8006007.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8271..10550
                     /gene="helD"
                     /locus_tag="ACN3HL_001118"
     CDS             8271..10550
                     /gene="helD"
                     /locus_tag="ACN3HL_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HHC8006008.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10643..11290)
                     /locus_tag="ACN3HL_001119"
     CDS             complement(10643..11290)
                     /locus_tag="ACN3HL_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006009.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11469..12188)
                     /locus_tag="ACN3HL_001120"
     CDS             complement(11469..12188)
                     /locus_tag="ACN3HL_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006010.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12319..13470)
                     /locus_tag="ACN3HL_001121"
     CDS             complement(12319..13470)
                     /locus_tag="ACN3HL_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HHC8006011.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13687..14427)
                     /locus_tag="ACN3HL_001122"
     CDS             complement(13687..14427)
                     /locus_tag="ACN3HL_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8006012.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="ACN3HL_001123"
     CDS             complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="ACN3HL_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HHC8006013.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="ACN3HL_001124"
     CDS             complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="ACN3HL_001124"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HHC8006014.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15388..16038)
                     /locus_tag="ACN3HL_001125"
     CDS             complement(15388..16038)
                     /locus_tag="ACN3HL_001125"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HHC8006015.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="ACN3HL_001126"
     CDS             complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="ACN3HL_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HHC8006016.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="ACN3HL_001127"
     CDS             complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="ACN3HL_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HHC8006017.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17481..18008)
                     /locus_tag="ACN3HL_001128"
     CDS             complement(17481..18008)
                     /locus_tag="ACN3HL_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HHC8006018.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18188..18973)
                     /locus_tag="ACN3HL_001129"
     CDS             complement(18188..18973)
                     /locus_tag="ACN3HL_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HHC8006019.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18966..19835)
                     /gene="accD"
                     /locus_tag="ACN3HL_001130"
     CDS             complement(18966..19835)
                     /gene="accD"
                     /locus_tag="ACN3HL_001130"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HHC8006020.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19836..21215)
                     /locus_tag="ACN3HL_001131"
     CDS             complement(19836..21215)
                     /locus_tag="ACN3HL_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HHC8006021.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="ACN3HL_001132"
     CDS             complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="ACN3HL_001132"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HHC8006022.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21667..22143)
                     /gene="accB"
                     /locus_tag="ACN3HL_001133"
     CDS             complement(21667..22143)
                     /gene="accB"
                     /locus_tag="ACN3HL_001133"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HHC8006023.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="ACN3HL_001134"
     CDS             complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="ACN3HL_001134"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HHC8006024.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGTKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="ACN3HL_001135"
     CDS             complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="ACN3HL_001135"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HHC8006025.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="ACN3HL_001136"
     CDS             complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="ACN3HL_001136"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HHC8006026.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25173..25397)
                     /locus_tag="ACN3HL_001137"
     CDS             complement(25173..25397)
                     /locus_tag="ACN3HL_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HHC8006027.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25450..26412)
                     /locus_tag="ACN3HL_001138"
     CDS             complement(25450..26412)
                     /locus_tag="ACN3HL_001138"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HHC8006028.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26422..26862)
                     /locus_tag="ACN3HL_001139"
     CDS             complement(26422..26862)
                     /locus_tag="ACN3HL_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHC8006029.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27168..28133
                     /locus_tag="ACN3HL_001140"
     CDS             27168..28133
                     /locus_tag="ACN3HL_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HHC8006030.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28190..28420)
                     /locus_tag="ACN3HL_001141"
     CDS             complement(28190..28420)
                     /locus_tag="ACN3HL_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HHC8006031.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28506..29393)
                     /locus_tag="ACN3HL_001142"
     CDS             complement(28506..29393)
                     /locus_tag="ACN3HL_001142"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HHC8006032.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29482..30705)
                     /locus_tag="ACN3HL_001143"
     CDS             complement(29482..30705)
                     /locus_tag="ACN3HL_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHC8006033.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30722..31768)
                     /locus_tag="ACN3HL_001144"
     CDS             complement(30722..31768)
                     /locus_tag="ACN3HL_001144"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HHC8006034.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="ACN3HL_001145"
     CDS             complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="ACN3HL_001145"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HHC8006035.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33659..33925)
                     /locus_tag="ACN3HL_001146"
     CDS             complement(33659..33925)
                     /locus_tag="ACN3HL_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HHC8006036.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34404..36638
                     /locus_tag="ACN3HL_001147"
     CDS             34404..36638
                     /locus_tag="ACN3HL_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8006037.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36786..37106
                     /locus_tag="ACN3HL_001148"
     CDS             36786..37106
                     /locus_tag="ACN3HL_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HHC8006038.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37311..37535)
                     /locus_tag="ACN3HL_001149"
     CDS             complement(37311..37535)
                     /locus_tag="ACN3HL_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HHC8006039.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37733..39313)
                     /locus_tag="ACN3HL_001150"
     CDS             complement(37733..39313)
                     /locus_tag="ACN3HL_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HHC8006040.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
BASE COUNT        11136 a         8568 c         6888 g        13087 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
     2401 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
     2461 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
     2521 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
     2581 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
     2641 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
     2701 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
     2761 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
     2821 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
     2881 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
     2941 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
     3001 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
     3061 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
     3121 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
     3181 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
     3241 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
     3301 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     3361 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     3421 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     3481 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     3541 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     3601 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     3661 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     3721 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     3781 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     3841 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     3901 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     3961 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     4021 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     4081 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     4141 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     4201 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     4261 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     4321 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     4381 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     4441 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     4501 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     4561 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     4621 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     4681 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     4741 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     4801 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     4861 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     4921 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     4981 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     5041 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     5101 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     5161 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     5221 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     5281 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     5341 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     5401 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     5461 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     5521 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     5581 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     5641 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     5701 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     5761 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     5821 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     5881 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     5941 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     6001 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     6061 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     6121 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     6181 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     6241 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     6301 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     6361 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     6421 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     6481 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     6541 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     6601 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     6661 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     6721 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     6781 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     6841 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     6901 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     6961 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     7021 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     7081 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     7141 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     7201 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     7261 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     7321 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     7381 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     7441 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     7501 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     7561 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     7621 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     7681 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     7741 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     7801 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     7861 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     7921 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     7981 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     8041 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     8101 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     8161 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     8221 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     8281 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     8341 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     8401 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     8461 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     8521 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     8581 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     8641 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     8701 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     8761 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     8821 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     8881 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     8941 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     9001 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     9061 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     9121 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     9181 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     9241 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     9301 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     9361 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     9421 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     9481 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     9541 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     9601 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     9661 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     9721 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     9781 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     9841 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagcct
     9901 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     9961 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
    10021 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
    10081 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
    10141 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
    10201 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
    10261 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
    10321 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
    10381 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
    10441 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
    10501 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
    10561 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
    10621 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
    10681 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
    10741 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
    10801 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
    10861 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
    10921 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
    10981 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
    11041 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
    11101 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
    11161 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
    11221 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
    11281 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
    11341 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
    11401 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
    11461 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
    11521 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
    11581 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
    11641 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
    11701 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
    11761 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
    11821 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
    11881 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
    11941 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
    12001 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
    12061 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
    12121 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
    12181 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
    12241 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
    12301 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    12361 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    12421 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    12481 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    12541 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    12601 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    12661 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    12721 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    12781 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    12841 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    12901 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    12961 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    13021 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    13081 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    13141 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    13201 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    13261 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    13321 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    13381 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    13441 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    13501 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    13561 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    13621 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    13681 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    13741 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    13801 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    13861 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    13921 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    13981 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    14041 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    14101 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    14161 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    14221 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    14281 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    14341 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    14401 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    14461 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    14521 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    14581 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    14641 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    14701 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    14761 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    14821 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    14881 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    14941 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    15001 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    15061 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    15121 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    15181 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    15241 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    15301 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    15361 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    15421 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    15481 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    15541 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    15601 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    15661 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    15721 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    15781 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    15841 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    15901 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    15961 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    16021 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    16081 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    16141 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    16201 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    16261 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    16321 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    16381 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    16441 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    16501 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    16561 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    16621 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    16681 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    16741 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    16801 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    16861 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    16921 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    16981 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    17041 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    17101 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    17161 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    17221 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    17281 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttgggtct cattataatg
    17341 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    17401 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    17461 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    17521 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    17581 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    17641 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    17701 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    17761 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    17821 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    17881 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    17941 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    18001 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    18061 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    18121 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    18181 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    18241 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    18301 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    18361 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    18421 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    18481 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    18541 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    18601 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    18661 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    18721 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    18781 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    18841 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    18901 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    18961 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    19021 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    19081 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    19141 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    19201 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    19261 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    19321 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    19381 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    19441 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    19501 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    19561 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    19621 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    19681 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    19741 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    19801 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    19861 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    19921 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    19981 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    20041 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    20101 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    20161 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    20221 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    20281 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    20341 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    20401 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    20461 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    20521 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    20581 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    20641 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    20701 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    20761 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    20821 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    20881 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    20941 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    21001 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    21061 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    21121 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    21181 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    21241 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    21301 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    21361 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    21421 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    21481 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    21541 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    21601 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    21661 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    21721 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    21781 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    21841 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    21901 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    21961 ttcagatatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    22021 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    22081 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    22141 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    22201 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    22261 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    22321 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    22381 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    22441 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    22501 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    22561 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    22621 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    22681 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    22741 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    22801 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    22861 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    22921 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    22981 ggtacgaaca ttggagaaac tcgttttgta cctttttcat gtagacgaat aacttggttt
    23041 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    23101 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    23161 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    23221 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    23281 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    23341 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    23401 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    23461 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    23521 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    23581 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    23641 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    23701 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    23761 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    23821 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    23881 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    23941 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    24001 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    24061 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    24121 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    24181 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    24241 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    24301 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    24361 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    24421 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    24481 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    24541 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    24601 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    24661 tcggcgcatt catcactgca accattttcc cgcttccagc tggggtagct tctgtcatat
    24721 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    24781 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    24841 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    24901 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    24961 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    25021 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    25081 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    25141 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    25201 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    25261 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    25321 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    25381 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    25441 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    25501 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    25561 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    25621 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    25681 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    25741 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    25801 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    25861 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    25921 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    25981 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    26041 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    26101 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    26161 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    26221 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    26281 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    26341 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    26401 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    26461 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    26521 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    26581 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    26641 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    26701 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    26761 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    26821 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    26881 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    26941 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    27001 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    27061 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    27121 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    27181 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    27241 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    27301 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    27361 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    27421 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    27481 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    27541 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    27601 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    27661 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    27721 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    27781 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    27841 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    27901 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    27961 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    28021 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    28081 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    28141 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    28201 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    28261 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    28321 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    28381 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    28441 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    28501 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    28561 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    28621 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    28681 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    28741 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    28801 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    28861 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    28921 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    28981 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    29041 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    29101 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    29161 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    29221 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    29281 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    29341 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    29401 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    29461 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    29521 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    29581 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    29641 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    29701 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    29761 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    29821 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    29881 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    29941 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    30001 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    30061 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    30121 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    30181 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    30241 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    30301 ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat acatcgtatg
    30361 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    30421 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    30481 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    30541 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    30601 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    30661 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    30721 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    30781 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    30841 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    30901 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    30961 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    31021 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    31081 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    31141 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    31201 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    31261 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    31321 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    31381 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    31441 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    31501 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    31561 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    31621 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    31681 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    31741 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    31801 tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta ctgacaaaaa
    31861 cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca caccagcttt
    31921 tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc catcatatcg
    31981 cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa gcgtttcatt
    32041 aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag acccatacct
    32101 actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc tgcccatttt
    32161 ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga tgggttatat
    32221 ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt gtattgaatc
    32281 aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc tgctaagact
    32341 gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac ttccttgcct
    32401 tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg gaattctttg
    32461 agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc acgaagcaat
    32521 gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat acgcaatgca
    32581 cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag ttctttatct
    32641 ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc taatacagct
    32701 ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat atacaggaat
    32761 tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac tagatctttt
    32821 ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac agtttctgca
    32881 ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc tttttcaaat
    32941 tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc gttgacagcc
    33001 aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat tgctggaatt
    33061 tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc tgttacaaac
    33121 gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc atgtgcaaca
    33181 acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa taagtgcgct
    33241 aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata agcattatct
    33301 tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc tgattcagca
    33361 tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg atctgaaaga
    33421 accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg cgctgctttt
    33481 tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa acgagcttct
    33541 tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg aactagcagg
    33601 taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat ttcaaccatt
    33661 attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca tcagcttcgt
    33721 cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa gacataacgc
    33781 ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca tcagagttaa
    33841 atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca gtttctgcta
    33901 ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt gttgttttta
    33961 tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc ctttcatctg
    34021 taaagattaa catttttttt cgttagatac aacagttttc attcaatttc agataaaagt
    34081 attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac aaacgtgttt
    34141 atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc ctttgaccct
    34201 ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta taataagagt
    34261 caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat ctcttaaaaa
    34321 actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat gtacccattt
    34381 ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat gaggcaacga
    34441 ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt cagagctgtt
    34501 atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa aatgatccat
    34561 ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg caacagcaag
    34621 gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc aatggtggtc
    34681 agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat atcacagaac
    34741 aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc aaacgagtca
    34801 ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa ccaggtgttg
    34861 gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat gtaccgcaaa
    34921 aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa ggtactggta
    34981 tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt caagcagaaa
    35041 atgtgatcct attcatagat gaagttcacg aaatcgtcgg tgctggttct gctggtgatg
    35101 gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa ttgcaaatgg
    35161 ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct ttagaacgtc
    35221 gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt attttgaaag
    35281 gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag gccatcgaag
    35341 cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat aaagccatcg
    35401 atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt gatcctaaaa
    35461 caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct cgagaagaag
    35521 atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa atgaaagaac
    35581 gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa aaaatcgttg
    35641 aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca caactgaaaa
    35701 acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta gatcgagtag
    35761 cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca atcggctcct
    35821 tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa cttgcctacg
    35881 aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat atggaaaaac
    35941 atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa gaagctggtc
    36001 aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat gaagtagaaa
    36061 aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt cgattgacag
    36121 atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca agtaatgccg
    36181 gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt gttactcgtt
    36241 ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt tttgacggga
    36301 tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca ctaatgctag
    36361 acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct acgaatgtca
    36421 aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct cttcgacgca
    36481 cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac ccttctatcc
    36541 atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct aaaccagaac
    36601 gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat agcgtgagac
    36661 ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa tactgttcat
    36721 tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata aaagaggtga
    36781 gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta aaccagcttg
    36841 aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact attgtctaca
    36901 ctgaagcccc tgaacataat gaaattctgc tgatcaatga caaacgtaaa atccagccga
    36961 aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc gtttaccacg
    37021 aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt ccaaaacatg
    37081 aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa agagcgtggg
    37141 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc gaaagcagaa
    37201 gcaactcctt cggaaataag ctgaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    37261 ccagcttatt tcttggagtt aaacgcttct gtctcagcct ctttttcttt ctagcttttt
    37321 gatttttctc ttttcttttg tacttttctc ttttcatttt cagttctacg cgtgtcttta
    37381 tttttaactt tttcctcttt atggatgatt gatcgtactt tttgtgcaat ttgctcgttt
    37441 ttgtcccagt cttttacatc taataatcga cataatcgta acatctcttc ttttttctgt
    37501 ttttttcttt cacgtctttg ccattctgtt tccatgtgtc acactctcct ttctttaatc
    37561 atatgtacgc aaaataattt ttatattttt ttgattagac atttctatga ttttaatata
    37621 gtaaaaagag ccgtcacgga aaatccgtca cggctctaaa caaaatatga gaggctgttt
    37681 ttgtttggct attcttatta cttgatgcag ggcagcttgt gtcaagactt ctttacatca
    37741 aactttttaa ttttacattg ggatatttat ccgcaaacca gcgttctgca aattggttct
    37801 cgaataagaa caacggttgg tcgaaacggt cacgagccaa gatattgcga cttgaactca
    37861 tcttctcatc caaatcttct ggatcgatcc agcgagcgat tttgtgtccc attggagaca
    37921 tgattacttc ggcgttatac tcatttaaca tacgatattg gaatacttcg aattgtagct
    37981 gaccaacagc tccaatgata tattcttccg ttagatatgt tttataaagc tgaatcgctc
    38041 cttcttgaac taattgatag attcctttgt ggaaggattt ttgtttcatg acattttttg
    38101 cagtcacttt cataaacagc tctggagtaa atgaagggag ttcttcataa gcaactttta
    38161 gttttccttc gaacaatgta tccccaatct gataattgcc tgtatcatat acaccgatga
    38221 tatcgcctgc tactgctttt tcgacgtttt ctctcgaatc tgccataaat tgtgtgacat
    38281 tgcttaattt cagtttttta tttgtacgtt ccaaccagac atccattcct cgttcgaatg
    38341 ttccagaaca gattcggaca aaagcgattc ggtcacgatg ggctggattc atatttgctt
    38401 ggatcttgaa tacgaaacct gaaaattctt cctcataagg acttaccatc tgatcatctt
    38461 gtgttttgtg tccataagga gctggtgcca attcaacgaa agtctctaaa aaagtctgta
    38521 caccgaagtt agtcaatgca gaaccaaaaa atactggtgt ctgatcgcca cgagcaattt
    38581 tttcttgatt aaatgcatct ccagcctctt tgattagttc tacttcttct aagacttgtt
    38641 catataagga attttcagtt agaggatgat tttcgggaag cagtccatct tcatccaatt
    38701 ctactaatcg ttcatcctga taattttccg gacgataaaa ctctacacga ttatggtaga
    38761 tatcataaag accttctagc cctttaccca taccgattgg ccaattcatc ggataagatt
    38821 cgatatctaa tagctcttct aattcttcta acaattccaa tggttcacga ccatcacgat
    38881 ctagtttgtt gataaaagta aatatcggga tgccacgttt ttttacaact tggaataatt
    38941 tctttgtctg tgcttcgatc ccttttgcac tatcgattac catgaccgca ctatccacgg
    39001 ccatcaaagt acgataagta tcttcagaaa aatcttcatg tcctggtgta tccaagatat
    39061 ttactcgttt cccttgataa tcaaactgca taacagaact agtaacagaa atcccacgtt
    39121 gtttctcgat ttccatccag tctgatttgg caaaattacc tgtttttttg ccttttacgg
    39181 tcccggcttg acggatagcc ccaccaaaca atagtaattg ttctgtaatc gttgttttcc
    39241 cagcatccgg atgggaaatg atcgcaaaag ttctgcgatt gtccacttgt tgctttaatt
    39301 ttggattatt cataacctaa ctccatttct tccattcaat tatttatatt ttctctaggc
    39361 acagattgtc cgatctctta aagaaagaca atttcatata gggctgtgac aaaagccgtg
    39421 tagcagtctc tttttccgag taaacggcgt tctagagaca gcctatcagc aataagccca
    39481 cccaagccaa aaatacgaaa agctgttttt gcttggctgc tcttattact taatgcagga
    39541 tagctttttc acaacctttg tcaactacta caactgaatc agtatagcat ggattcagcg
    39601 aatgaaaaag ccaccaaacc ataagagtca aatatttttt tgtcagctga ctaaaagaaa
    39661 agacgtgttg cttgtttat
//
LOCUS       DBGZHO010000018        39584 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.018, whole genome shotgun sequence.
ACCESSION   DBGZHO010000018 DBGZHO010000000
VERSION     DBGZHO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.018"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(448..2355)
                     /locus_tag="ACN3HL_001151"
     CDS             complement(448..2355)
                     /locus_tag="ACN3HL_001151"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HHC8006041.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            2485..3360
                     /locus_tag="ACN3HL_001152"
     CDS             2485..3360
                     /locus_tag="ACN3HL_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HHC8006042.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            3440..4414
                     /locus_tag="ACN3HL_001153"
     CDS             3440..4414
                     /locus_tag="ACN3HL_001153"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HHC8006043.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            4594..5739
                     /locus_tag="ACN3HL_001154"
     CDS             4594..5739
                     /locus_tag="ACN3HL_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HHC8006044.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            5876..6220
                     /locus_tag="ACN3HL_001155"
     CDS             5876..6220
                     /locus_tag="ACN3HL_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HHC8006045.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            6491..7777
                     /gene="efmA"
                     /locus_tag="ACN3HL_001156"
     CDS             6491..7777
                     /gene="efmA"
                     /locus_tag="ACN3HL_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HHC8006046.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(7915..8514)
                     /locus_tag="ACN3HL_001157"
     CDS             complement(7915..8514)
                     /locus_tag="ACN3HL_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHC8006047.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            8918..10039
                     /gene="mnmA"
                     /locus_tag="ACN3HL_001158"
     CDS             8918..10039
                     /gene="mnmA"
                     /locus_tag="ACN3HL_001158"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HHC8006048.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10285..11706
                     /gene="arcD"
                     /locus_tag="ACN3HL_001159"
     CDS             10285..11706
                     /gene="arcD"
                     /locus_tag="ACN3HL_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HHC8006049.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            11720..12838
                     /locus_tag="ACN3HL_001160"
     CDS             11720..12838
                     /locus_tag="ACN3HL_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HHC8006050.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(12898..14190)
                     /locus_tag="ACN3HL_001161"
     CDS             complement(12898..14190)
                     /locus_tag="ACN3HL_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HHC8006051.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            14340..14900
                     /locus_tag="ACN3HL_001162"
     CDS             14340..14900
                     /locus_tag="ACN3HL_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8006052.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            15029..15406
                     /locus_tag="ACN3HL_001163"
     CDS             15029..15406
                     /locus_tag="ACN3HL_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HHC8006053.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            15339..17411
                     /locus_tag="ACN3HL_001164"
     CDS             15339..17411
                     /locus_tag="ACN3HL_001164"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HHC8006054.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(17622..18569)
                     /locus_tag="ACN3HL_001165"
     CDS             complement(17622..18569)
                     /locus_tag="ACN3HL_001165"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8006055.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            18815..19279
                     /locus_tag="ACN3HL_001166"
     CDS             18815..19279
                     /locus_tag="ACN3HL_001166"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HHC8006056.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(19341..20384)
                     /locus_tag="ACN3HL_001167"
     CDS             complement(19341..20384)
                     /locus_tag="ACN3HL_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HHC8006057.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(20761..21726)
                     /locus_tag="ACN3HL_001168"
     CDS             complement(20761..21726)
                     /locus_tag="ACN3HL_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HHC8006058.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            21960..22805
                     /locus_tag="ACN3HL_001169"
     CDS             21960..22805
                     /locus_tag="ACN3HL_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8006059.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            22996..24183
                     /locus_tag="ACN3HL_001170"
     CDS             22996..24183
                     /locus_tag="ACN3HL_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HHC8006060.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            24189..24545
                     /locus_tag="ACN3HL_001171"
     CDS             24189..24545
                     /locus_tag="ACN3HL_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HHC8006061.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            24547..24885
                     /locus_tag="ACN3HL_001172"
     CDS             24547..24885
                     /locus_tag="ACN3HL_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HHC8006062.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    24961..25217
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25280..26314
                     /locus_tag="ACN3HL_001173"
     CDS             25280..26314
                     /locus_tag="ACN3HL_001173"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HHC8006063.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            26307..26993
                     /locus_tag="ACN3HL_001174"
     CDS             26307..26993
                     /locus_tag="ACN3HL_001174"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HHC8006064.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            27017..27865
                     /locus_tag="ACN3HL_001175"
     CDS             27017..27865
                     /locus_tag="ACN3HL_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HHC8006065.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            28062..28835
                     /gene="sufC"
                     /locus_tag="ACN3HL_001176"
     CDS             28062..28835
                     /gene="sufC"
                     /locus_tag="ACN3HL_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HHC8006066.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            28848..30134
                     /gene="sufD"
                     /locus_tag="ACN3HL_001177"
     CDS             28848..30134
                     /gene="sufD"
                     /locus_tag="ACN3HL_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HHC8006067.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            30131..31366
                     /locus_tag="ACN3HL_001178"
     CDS             30131..31366
                     /locus_tag="ACN3HL_001178"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HHC8006068.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            31353..31823
                     /gene="sufU"
                     /locus_tag="ACN3HL_001179"
     CDS             31353..31823
                     /gene="sufU"
                     /locus_tag="ACN3HL_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HHC8006069.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            31828..33219
                     /gene="sufB"
                     /locus_tag="ACN3HL_001180"
     CDS             31828..33219
                     /gene="sufB"
                     /locus_tag="ACN3HL_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HHC8006070.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(33314..34456)
                     /locus_tag="ACN3HL_001181"
     CDS             complement(33314..34456)
                     /locus_tag="ACN3HL_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006071.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(34495..35229)
                     /locus_tag="ACN3HL_001182"
     CDS             complement(34495..35229)
                     /locus_tag="ACN3HL_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8006072.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            35461..35736
                     /locus_tag="ACN3HL_001183"
     CDS             35461..35736
                     /locus_tag="ACN3HL_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006073.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            35834..37831
                     /locus_tag="ACN3HL_001184"
     CDS             35834..37831
                     /locus_tag="ACN3HL_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006074.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(37907..38242)
                     /locus_tag="ACN3HL_001185"
     CDS             complement(37907..38242)
                     /locus_tag="ACN3HL_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8006075.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            38369..38584
                     /locus_tag="ACN3HL_001186"
     CDS             38369..38584
                     /locus_tag="ACN3HL_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8006076.1"
                     /translation="MKKVNNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            38621..38983
                     /locus_tag="ACN3HL_001187"
     CDS             38621..38983
                     /locus_tag="ACN3HL_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HHC8006077.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            39029..39355
                     /locus_tag="ACN3HL_001188"
     CDS             39029..39355
                     /locus_tag="ACN3HL_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006078.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
BASE COUNT        12902 a         7059 c         8261 g        11362 t
ORIGIN      
        1 tttttataga tgaggttctc cttgctgctt ttgattggct gttcttatta cttgatgcag
       61 gacagctttt tcacaatctc tccactaaac ggtgttcaat cagctgaccc tcggtattag
      121 ctcaacaaac ggcaaaatat gaggaactat ttttccgttt ttttctctaa tactcaggtc
      181 aggacgctga tttcacaacc tctcgataaa cggtgttcaa aagccagttt ctcggtagta
      241 agtcaaattt atgcaaaaat gtggaaagcc attttcacaa aatttttctt actacttgaa
      301 actaagcagc tttttcacaa cctctaatac atggtattcc agaagtaact tcttcgaaaa
      361 ataagccgaa atgtcacaaa aatttgagaa gcgattttcc caaattcctt cttatttctt
      421 gaagctgacc acttctggca caacctctta ccagattcgc actctttttt ctggcgctag
      481 atacatagcg tcttgttccg tgataccaaa tgtttcatag aattcgtcaa ggttttttgg
      541 ttgcacgttt gctcggagtt tagcaggggc atggacatcg atttgcagta aaagttgttg
      601 gtattctttt tttgcttttg tacgccaaat cgttgcccaa ttgacaaaga attcctcgat
      661 agaaagatct gattccgttt ttgctgcttc caatgcacag cttagaccgc ctgcatcagc
      721 aatattttcc gaaacggtta attttccgtt tacttttccg tcagcaaaag gcagaccatc
      781 gaattcttcg atcattgctt gtgctttgtt ttgaaattgt gtaagatctt cttctgtcca
      841 ccagttgttc aagttgccat attcgtcaaa taaagcgccg ttattatcaa atgcatggga
      901 aatctcatga gcgataacag ctccgattcc accataatta gcagagcttg attgttctag
      961 actgtaaaat ggtgcttgaa ggatcgctgc cggaaagacg atcacattcc gaaatggatg
     1021 ataataagca ttgaccgtgt cagcactcat ttcccattct gaacgatcca ctggtttgtt
     1081 ccatttgctg aaacgatctt ttaatgtgag tttgctgaaa acaagagtat ttgaaagcaa
     1141 agtaccaccc tgatctgcag gtactgtttt gaactggtcg aataatgctg ggatcttatc
     1201 ggggtagcct acttggatac ctaagttatt taattttatg acggcttttt cttttgttgc
     1261 atccccaagc cagtcatttt cttctagacg ttttttataa acggcgatca tttttttcac
     1321 catttgttct acgtcttttt tagcagcttc gccaaaatat ttttttccgt agtaatcgcc
     1381 aactacttga tcgaattgtc cagaggcaag gtaatacgct gcttttttct gaggcattgc
     1441 ttcgtctgtt ccagacaata cgcgagaata gattccgctg acttggcgga attcttctga
     1501 tagataacca ctaagagaac gtactgtttt aatgatcatc cagcttttga ataacggaaa
     1561 atgagcttct gtcaggatgt cattcaaatg atcgaagtac actggatcag ttacgatcac
     1621 tttatctgga gttgtcccaa tcaaacccgt gacaagtttt ttcaagtcca gtttatctgt
     1681 gtatttaata aatgtatcaa aagattgcgg attatacatt ttgctgtaat ctgcgttttc
     1741 ttctgcactt tttacatgag gagcaatcaa tttatcaaat tgcactgctt gttccgtgat
     1801 tgcttctgcc tgactttttt ctttgccggc aagctctaat aactgaacag ccatatcaaa
     1861 gaaaacgcct attagttgtg caccgttggg atggtctgat gcataatacg tcttatctgg
     1921 aaggaataaa gaaggcggat aagcaaagaa ggcgttcgtt tgcgcattct tcatatctgc
     1981 atctacatcc agattaaatg gcaatggtaa tgtatccaac agccattctg gaaattgctt
     2041 attcaattcg tcgaaagact gcaatgattc aactttttcg attataggtt gaagcggttg
     2101 agcatgcaac tcatttcttc ggtcataatc gtttgccagt tgataatatg caaggaaatg
     2161 tttcattttt tctgaagaca ctttttctgg atgggcaagc agatcgtctg tttctcccat
     2221 caaaagttgg tcgatcccgt caactaaatc ttggaaaccg cctgtagctg gtttatctgc
     2281 agggattttt gctgtttttt gccattcttc attgactgct tcatagaaat cttgtttcaa
     2341 tcgttctttg ttcattcatc gatcgctcct tttttgtttc gtgtgcccat tatcttacaa
     2401 aatgaaggaa ttaacaaata gaacataaaa aattgaaaat tcgaacaatc aaactgattt
     2461 gtttttttca atccttcact tataatgaaa aaaaggaggc gatcccaact gaatcaagta
     2521 gtggataaac ctttatattt caaagtagat aaaaaaatta aaaaattagc cagcactcag
     2581 cagctgcagt caagaaaaag taaattgctt tttttagctc tggtttttga agatcaaagt
     2641 tatgtgatta tcgatcaatc aggacatccg gtagaatatt ctccagcaaa atatacttat
     2701 caagagggtc tttcttgtaa aaaatggaag ctgatcaatg aagagccaat cgagttatct
     2761 agatggatca acagaaaaga agatattccc gttttgatcg aagaaaaaag gtcaggaaag
     2821 gaactcgcaa attgctgggt gggattgcca gaagaacgtt ttttgaggta taagaaatgg
     2881 gctaccccct caggctatct ttgtggtact tacgcggcag cagttctcct tgcctattat
     2941 caagactatc gtaaggggtg gatgcttcca aatgagattc gcaagaaaaa tacggctgat
     3001 tcgttggttt tgacgaaggc attgcgtagc cagatccaac cactaggact tcctacgatt
     3061 ccttttcagg ttagtacagg gatttctagt tttttaaaga agaatggcaa tcatgagcgt
     3121 gcacgagcaa ctcttctagg ttcatggcag cgagctacaa aacgtatacg tgaaggcaaa
     3181 cctgtgatga ttggtatttt gaaagtactt ggcagtacat atggcaatca ttgggtgaca
     3241 gcgtacgctt attttgaaac tgaaacagga gaacgttatt acaaagtaca cgacaactgg
     3301 ggcgattatc ataaagtcat tcctgccagt tggagtaacg gaacagtttc acttccttaa
     3361 gaatttgctg aaattaacag aaaatcttgg aaaaatatgt taaactatcg aagaatagag
     3421 aagttttggg gaggactaca tgagtaataa gtatcaggat gacacgttga agatttttag
     3481 tttgaatggc aaccgtccat tagctgaaaa aatcgcgaaa gtgttcggaa cagaattagg
     3541 taaaagcgtc gtgaagcaat ttagtgatgg cgagatttcc atcaatatcg aagaaagtat
     3601 tcgaggggat catgtgtata tcgttcaatc aacgaatgca cctgtcaatg attactatat
     3661 ggaactactg atcatgatcg atgcaatgaa gcgagcaagt gcgaaaacga tcaatgtcgt
     3721 attgccttac tatgggtatg ctaggcaaga ccgcacggcg aaacctcatg aaccgatcac
     3781 tgcgaaattg atcgctaact tgatcgaaga agcaggggca actcgagtac tgactttaga
     3841 tctgcacacg gttcaagtac aaggattctt tgatattcct gtagataatt tatttacgat
     3901 gccgttgttt gctcattatt accgtcaatt aggtctgacg ggagatgaca tcgtagttgt
     3961 ttcgccaaaa aacagcggtg ttcagcgtgc acgtagtctt tcagaatatt tgaacagcac
     4021 attagccatc gtagatcatg cagatgatgc ttcaactgag ggtggttatg tgatcggtga
     4081 tgttcaagga aagacatgta tcatggtaga tgatatcttg aacacaggag caacgcttgc
     4141 acgagcagca aatgtattaa aagaaaacgg cgcaaaagaa gtatatgcct gtgcgtcaca
     4201 tggattattg tccgatcatg cgaaaagtat tttagacaat gcaccaatca aagatatttg
     4261 tatcactgat tctgttttca cagaagaaaa tcgtcatcca gaaaacttaa caatcgttac
     4321 atgttcagaa ttaatgggtg aagcggtcaa acgcatccat gaaaatacac cgatgagtcc
     4381 gttattccgt ctggaagaaa aagaattcga ataaacaaaa aaaagaggga aagaagttgt
     4441 gacagaagtg agcagcttca aggagctgcg acaagacttt tgtcacagct ccttttttct
     4501 atgcccatga aacgtcctct agacaaaaat gagctcttct ttggtttgtt cgctatttta
     4561 tgctagaatg tgcctagcaa taatttggaa gggatgaatg aagtgaaaac tatttatctg
     4621 gatcatgcgg caactacccc catgcatcca caagtaattg aagcgatgac ggcaatcatg
     4681 caagacacgt ttggaaatcc ttcaagcata catggatttg gtcgccacgc gcatgaaaaa
     4741 ttggaaacag caagacaaat cattgcagac agtctgcaag caaaacctca cgagatcatc
     4801 tttaacagtg ggggaacaga aggggataat acagctatct tagaaacagc gttctcgcgt
     4861 caaaaagaag gcagacatct aatcactaca gctatcgaac atcctgctgt tcttaatacc
     4921 atgaaatatt tagagacaaa ggggtttgac gttacatatc tgcctgtaga tgaaaaaggg
     4981 aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag atacgatctt ggtctctgtg
     5041 atgtacggga acaatgaaat cggaaatttg atgccaatca aagaaatcgg tgaactttta
     5101 gcggatcatc cagcttattt ccatacagat gcggtacaag cgtacggaaa ccaaacgatc
     5161 catccagaag aattaggaat cgatttatta agtatctctg ctcataaaat caatgggcca
     5221 aaaggcgtcg gtttcttata taaacgagac ggagtaaata tccctgcatt gcttttaggc
     5281 ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat ctggggtatg
     5341 gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag cacgtaacaa caaatataaa
     5401 ggattccagc aattgattct tgatacatta gaagcaaacg aaatccctta tcaagtaaat
     5461 ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc gcttaattgg cgaagcaaat
     5521 gatttgctac tgatgaagct tgatcttaat ggggtcgcta tttctactgg ttcagcttgt
     5581 acagcaggaa atatcgagcc ttcacacgta ttagaagcaa tgtatggaga agatacaccg
     5641 atactaaaag aatccatccg tatcagcttt ggtttgggaa ataccgaaga cgacatccag
     5701 tatttccttg atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc attcttatat
     5761 gaacagatgt ctgagagaac gccttcattt tttagggaac ttaactgaaa aacctagtaa
     5821 aaatcaggat aaacttttat aataaagaga aactaatttt atcgaggtga aaatcatggc
     5881 atttgaaaca acagcaacgg tactgggcgc accaattagc tatcgtttgc atcctgatgc
     5941 aaaaagatat acattgcgcg ataatggatt tacagaaaca aacggaggca attatcaatt
     6001 gatccgacca ttagatgcca cgccgcaaag caaagaagga ttcaaattaa aaatcactgt
     6061 atcaaaagat attcaaacat tgaaaatgtc gatcactaca gcaaatggat tgaaagcagt
     6121 caatattttc aaagatccaa aacagaaaat gagccaagat aaattttatt ttctgatgga
     6181 tgggatgatt agccgtgggt tattcgaaaa agtcgaatga tctgtggata taaaaagaca
     6241 actagttttg aaacggccta ttgttagatg actaactttg taaggacgac gcaaattagt
     6301 tgtctttttt atttttaaat ttaacacatg ttgttatttt taatattttg ctgatttatt
     6361 gtttctaagt aaagaaattt aaattgaaac gattgttatt tagggaaaaa ggtatttttt
     6421 gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta tacaaaatga aaaagaaaag
     6481 agggatgttt atggaaaatg aacagtcggt cgttttaacg aattggaaga gaaattattt
     6541 gttcttttta tcgggacagt ttttgtcagg aatcactagt atggtcgtcc aatatgcgat
     6601 catctggtat ttgacaagag aaaccggttc ggcgacaatt ttgagttttg ctactttact
     6661 aggaatgatt cccatggttt tactaagccc atttgtagga ccgctagtgg atcgctggga
     6721 taaaaaagct cttttgattg tcacggatat tattgtagcg attttcgcgc ttattttagc
     6781 agtagtcgga acgatttcag aatccttccc gatttggcta gtttttgtgt ctttgtttat
     6841 gcgttcggtc gcacaaacat tccaaatgcc aacgatccag tcgattatgc cgacaatcgt
     6901 tccatcttct cacataacaa ggacgaatgg acagttagga atggtccaat cagcgaattt
     6961 catcattgcg ccagctctag gtgcggcttt gttttcagtc gttcctgtca attaccttat
     7021 tttattagat gtattggggg cagtttttgg tgtcggctta ttgatttttg tgaagatccc
     7081 aaaagtttct cctgaaatat tggaagttcc gcttactatt tttaaagatg caaaatttgg
     7141 gctgcagcaa ttgatggata ataaagggtt atggtacata acgatcaatg gtgcatttgt
     7201 gatgctgttg ttcatgccag caatcagtct gtatccattg atgacgctag attactttgg
     7261 tggttccgtt ggacaggcgg gagcagtgga agtagtctac gcagtcggaa tgctcttagg
     7321 cggtgcactg atcagtttta taggaacatg gaaagaccga atgaaaccta ttattatagc
     7381 ctacatcatt atgggcctga cgatcggtgc aagcggattg gttccaaacg atagtcaagg
     7441 gttcttgtac tttcttatct tgaatgcagg agcaggttgt gcaacgccat atttcaatac
     7501 actgctgatg gcaatgatcc agcagagtta tgaatcgaat gttttaggtc gtgtcttagg
     7561 gaacttcaac tctttgatga acctggcagg tccaattgga ttattatttg caggaccatt
     7621 agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc ggaatcggga ttttattatg
     7681 cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat gataaagaat tacagaaaaa
     7741 actggtaaaa gaacaccatg agcaaaaaga cgaatagtat ggaatggagt tgtgacagaa
     7801 gtcttgttac aactccattt ctgatcctaa tgttcctgtg gcaataagcc tactcaaatg
     7861 aaaaatatga gtaattatct ttatttgttt aatacttgat atagggcagt tttttcacga
     7921 cctatcgtac ttcctctttg cttcatagat ttctttgatt tgttgctcag ataacggagt
     7981 gccaaatggt agtttttcct ttaagagttc tctttccggt gcgtctacgc ctacattgac
     8041 atcgttctcg ataggtacgc tgtaatgatg gatatgtcca tgaagattgc ggatagtgtc
     8101 gttaggcccg agcaacatcg gataatgagt caagtaatat tgttgatggt cgaatttaac
     8161 gatggcacct acatcataaa aataaaattt gggacttccg tcagtaagcc taggatcatt
     8221 tttttctaaa taacggaaaa aagcgcgact gtcatggttc cctttgatca agtggattgt
     8281 tccttgcagt tgagtgacca gttccaaaat ttctgcattt gctttttcat attgcggatg
     8341 catagcaagg tcgcctagat gataaacatg gtcggtttct tttattactg cattccagct
     8401 agtgatcaac tgttggttca tttcatccac atttgcaaag agccgcggag caaagtcgtt
     8461 ttttcctaat aagcgttcat ggaaaaagtg catatcactg ataaagtaat tcatgtatct
     8521 tttgcctccc ttttttctta gagtaaacaa aatcacttat ctgagcaact cataacatct
     8581 aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg ataagaagca attttgaaaa
     8641 atagtttttc acaatttata aaattattcc ttattgccga aaggctggcc ctttttatga
     8701 gtatgccaat tttttatatc gaatgctcaa aagatgagtg attttttggt tgactatcat
     8761 gtttgtgtac tgaataggtc cagtagaaca gtatttttac gacttgataa ttaagggatg
     8821 aaattttcag aaatatgacg tataatgtaa aatactgaaa agttgcgacc ttcaactcgt
     8881 agatgtttca gaatctaatt gaaatgatgg tgatatcatg acagacaaca gcaaaacacg
     8941 cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta acagcacttt tgttaaagga
     9001 acaaggatac gacgtgatcg gaatattcat gaaaaattgg gatgacacgg acgaaaacgg
     9061 tgtatgcacg gccacggaag attataagga tgtagcgaaa gtagctgctc aaatcgggat
     9121 tccttattac tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg aatatttcct
     9181 agccgaatac cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca aagaaatcaa
     9241 attcaaagca ttcttggatt atgcaatgga tcttggcgcc gattatgtag ctactggaca
     9301 ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg gagtagacaa
     9361 taataaagat caaacttact tccttagcca attatcacaa gaacagcttt caaaaacgat
     9421 gttccctcta ggcggcatgg aaaaatcaga agtacgggca attgctgaac gcgcaggcct
     9481 tgcgactgct aagaaaaaag attcaacggg aatctgcttt attggtgaaa agaacttcaa
     9541 acaatttttg agcaactatc tgccagcaaa aaaaggaaat atggtcactc ttgatggtga
     9601 agtcaaagga caacatgctg gcttgatgta ttatacgatt ggtcaacgtc aaggactagg
     9661 gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag atctagcgac
     9721 aaacacatta tatgtggggc aagggttcca tcatcctgca ttgtatgcca caagcttgga
     9781 tgcaagtgaa atccacttta cgacgaatga accaatgcca aaagaattca agtgtacagc
     9841 gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg atgataatcg
     9901 tgcagaagtc gtattcgacg aacctgtacg tgcaatcact cctggacaag cagttgtatt
     9961 ttatgatgga atggaatgtc tgggtggtgg tttgatcgac cacgcatatc aagaaacaaa
    10021 agttttacaa tacgtttaag cgatattaaa tgaatcaaaa cagctatggc taacaaaaga
    10081 aacacctttt cttttggata gcatagctgt ttttttgcaa taaaattaat ttttattcat
    10141 tttatacttg aaatacttgt gtaaaaagtt cataatatcc aataatatga ataaagttgc
    10201 tttttgttaa gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt gatttgttca
    10261 attttataag tgagggtgat ggaaatggaa aagaaatcga cgggtattag caaatgggga
    10321 ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat cacaagtgat
    10381 ctggctagtt ctgcagctcc agggccagcg atcctttcat ggataatcgt tgggattggt
    10441 attttagctt tggtattatc gctgaatcat ttaggagaaa agcgtccaga tctagatggt
    10501 ggtattttcg gttacgcgga agcttcattt ggtaaattag gtggcttcat cagtggttgg
    10561 ggttactggt tgtctgcgtg gctgggaaat gttgcttttg caacgatgct gatgagcgcc
    10621 atgggagaat ttttcccgat attcaaaggt ggacaaaatg ttccttctat tttatttgca
    10681 agtattttta tttggggtct gactttatta gtaaacaatg gagttgaagg agcgagcgtc
    10741 atcaatacaa tcgtgacgat ctgtaaatta gtgccattat tcctattttt aatatttgta
    10801 tttatcgcat ttaaagtgaa tatattcact gctgattttt ggggtaacgt atctgataat
    10861 ctagtgaatg gaacagggca gcaaggaacg atctggttgc agattaaagg ttgtttgatg
    10921 gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa ccgcgcgaag
    10981 aaacgttcag aagcccagca agcatcgatc attggtctgc tttgtttatt gtttatctat
    11041 atccttgctt cgatcttgcc atacggcgtc ttatctcaag aagagttagc aactatttca
    11101 caacctgcta tggcaaatat tttaaaagga atcgtgggaa attggggagc agcgctgatc
    11161 aatatcggct tgattatttc gatcattggt tcttggttgt cttggacgat gctcccagca
    11221 gaaacaacga tgttgatggc tcgagacggt ctgttgccga aaggttgggg aaaaacgaat
    11281 aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa tcttgactaa tctattctta
    11341 ttgactttct tagttactga ttatgcctat caatttgcct attctttatg tacagcggca
    11401 attttgattt gttatctact tgtcgggatc tatcaagtcc agttttcttt aaaagaagga
    11461 atcaaaaaac aagtagtgat cggtgggatt gctgtagttt ttgaattgat gggcatcatt
    11521 ttagcaggat tttcttatgt ccttttatgt agtattgcct atcttcctgg tttttgcttc
    11581 tactggatcg cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa agtaatgatt
    11641 gggctgattt gtgtggccgc actgctttca atcgggttgc ttgctgtagg ctggatcaag
    11701 atataagggg gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat ggctaaataa
    11761 atgggaaaag aaagcggtat atgatattgc acaaagctcg atcgaagcat tgacattaga
    11821 cgaactcgtt ggcttagatg ggactagcgt aagtaaattt ttcgaaaaac gcaaaaacga
    11881 accattggac tatggctgga tcgaaggatc agatgttttc aaacaagaag tcgcttctct
    11941 ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat ggagcgactg gtgctaatct
    12001 tttagctcta tacgcgttag tggaagcagg agaccatgtt gtttcgatgc ttcctactta
    12061 tcagcaatta tatgacatcc ccaaatcttt aggtgccgct gttgactttg ttcatttgaa
    12121 ggaagaagaa gattggcagt ttgatttaga acagctagaa gccttagtca aacctgaaac
    12181 aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc acattgctag atcggaaaac
    12241 tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca tatgtattga tagatgaagt
    12301 atatgcgcct ttaacggata aaggtgaatt cttgtcgatc gtagatgtct atgaaaaagg
    12361 tatagcaacc aattccctat ccaaaaccta ctccattcca ggtattcgta ttggctggac
    12421 agctactgga cctgagttgg cagaagtttt tcgaaagtat cgagactaca cgatgatttg
    12481 cggcggagtc ctgtcagatg atcttgctgt acatgcattg aagaataaag aaaaaatatt
    12541 ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat gggtagccaa
    12601 tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct acttctttca ttaaattagc
    12661 catcgaagaa gatgaccaga cattttgtat caatttatta gaagaaacag gagtactatt
    12721 agtaccagga agtgcctttg atttaccgaa gcatgcccga ctaggttact gttgtaaaaa
    12781 agaaaccttg gaaaagggat tattcctctt atctgagttc ttgaaaaaac aggcctaaac
    12841 aaaaacactg caaggacagt ctgtgacaac tgttcaagca gtgtttttca tttacgctta
    12901 ttgtctatga gaaggagagt gccctgaagc tatggagact cctgaagctt tttcttctgc
    12961 agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca agcaagaagt tgaccaaaac
    13021 aagaagagaa gtcgaaagaa agacgccacg ataaccaaat gcactggaaa cactggagcc
    13081 gatcataggc cctactacgt taccagttgc ttggaaagat tggttataac tgaagatccg
    13141 tccagcagct tgatgaggcg aatattttgt gatcaatgct tggacagcag ggagcagaca
    13201 agcatcagag ataccaatca aaaaacgtaa ggcagctaat tgccaaacat tcgtgacgaa
    13261 tgccattggg atataaacca gaatcgcaaa acccaaacca atcgcaagta ttctttcact
    13321 cccaatcttg tcacctaagc gaccaaatct tggagcggct atcaaagtgg caatcccagg
    13381 tatcgaagca atgattccgc tgatcaacgt aacattccca tgtccatgca gcaattggcg
    13441 aatgtacaga ctgatgattg gactaatgga attgttggat gcttggatga tcatcgttgt
    13501 gacgaacata ccgatgacga cgtgtggata tttcaagtct ttgaaaatct gtttggcaga
    13561 aaccatgttt tcttttttca ctgggacaaa tttttcatgg acgaaaaaca gactcaacaa
    13621 gaagacgaaa aataagatga tccctgtaat gaaaaaggta gggcgatagc caaacgctga
    13681 agcagagatc ccgccaagaa gcggtccaag taatgttcct gtaacagaac cagttgctaa
    13741 ggttccaaga acttgaccac ttttttcttt tggcgtccca gttgcgacaa gggcagtggc
    13801 attactgata taaccagaaa aaatcccttg aagcagacgc aatgcgacta attgatacac
    13861 actagtcacg caacccatca aagaaatgac gattgccatt cctaatgaag cacgcaacag
    13921 catcaatttt cttccttttt ggtcggctaa ttttccccac caaggagaga taagcgtagt
    13981 caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg acgtactata
    14041 attacctaac gtatctatgt aaagtgacat aaaaggcatg actaaactaa atccgatacc
    14101 agccataaat gttccaaacc ataagacaaa caagttttgt tcccaagttt ctcttttcct
    14161 aaataatttt tcctttattc ttgcagccaa ttagactcct tctttctgaa aattttcatc
    14221 tacagctctt tattataaac tacaatatgt agtttatcaa tgaaagtctc ttttttctct
    14281 ttctttttcg tggtaaactg aaagagtgaa ggatttattt tatgagagga aacatggaaa
    14341 tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg ctttcgagaa ctagcagaag
    14401 agatggatgt tcagcaaata acctttcagc atttagccaa acgcttggat atcaaggctc
    14461 cctcgctgta taaccatttc aaaaatattc gtgatgtcaa aacagcgcta acagcgaaac
    14521 ttctgcagga acttaatgac cagctgcgac gggctcttgt gggaaaaagt ggtcaggaag
    14581 cactgcagat ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa gcagtgtatg
    14641 agttactgat cagtgtaccg cataccaatg aagctgtttt attagatgga atccatgaaa
    14701 cgaatcagat cattttgcag atatttgagg cttttcaatt aacgaaagaa gaaaaagttc
    14761 atcgaagcag ggaacttcgt agtatgatcc acggttatct ttccttacgt tttttaggat
    14821 actttacaaa agaaccaaca atcgatccag aagacagcta tttttggatg atcaataact
    14881 ttatcgctac tttgccttaa acaatcagat tcatttgtaa caattttaag atgttcatta
    14941 aatgaccctt ttataagaga aaattcttgc aactttcttg aaaagtgact aagatgagtc
    15001 tagaaaagct gaaagaagga gcacgagtat gtatcaagta attaccatgt tcggggacaa
    15061 tgagccttgg tggttttttg aagactggga agaagatatt gaagaagaag aaacattcga
    15121 gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc atcaaaatta
    15181 tgaatatatc aatgcaaaaa gtaactttct cagcgccttt tggaatgacg gagatgagcg
    15241 ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag ggacttgcgt tgttgaaaaa
    15301 tcatcagccc atcacagtag aaagcagaaa ggaattttat gaaacaacta attctagcgg
    15361 aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa aagcacaaaa
    15421 attattatga aggacccaag gtgatcgtta cttgggccct tggtcattta ttaggattga
    15481 aaatgccgga agatctgaat aaggaatggc agagctggca aatggacacg ttgccaatga
    15541 tccctaaaaa actaggaatc aaaccacttc ctaaaacagg acatcaatta aaagcaatca
    15601 agcagctggc tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat gccggaagag
    15661 aaggggaact tgttgctcgc tggatcttag agtatgtgca tttcaataaa ccagtgaagc
    15721 ggttatggat ctcttctcaa acagataaag caatcaaaac tggattcaag caactaagac
    15781 ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa gcggactggc
    15841 tggtaggatt gaatgtgacc agagccttaa ctgtgaagta cgcggataat ttatcagcag
    15901 gccgtgtgca gacaccgaca ctagcattag tgagagacca agaaaagaaa atcgagcagt
    15961 tccgtccaca aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa gccaaaatgc
    16021 ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc acaaaaactt gttcaattga
    16081 tcagtacaag caaaggaact gtcacagaag tccaagaaaa attaaaaacg gaatctgcgc
    16141 cattgcctta tgatttaaca gagatccaaa gagaagccaa tcaacgctat ggctattctg
    16201 caaagaaaac attaagtctt gtacaaagtt tgtatgagac ccataagatc gttacttatc
    16261 cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa gaacgattgc
    16321 aagcagtcag cgactttgct cctgaggtca agcagtattt gaaaaacgga gccatcgtcc
    16381 aacagacaaa agtattccaa gacagtaaag tgaccgatca ccatgcactt ttgccaactg
    16441 aaaacagagc acgttatgaa aaattaagta atgaagagcg aaaaatctat caaatgattg
    16501 tctctcgttt tttaggactg tttgctcaac cccataaagt cagccaaaca aaagttacgg
    16561 ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa gcaggatgga
    16621 aaggcgaaac tgaaactgag acggaaacag tcaaatggga aaaaggaatg agaatcaatc
    16681 ccgatttcgc catcaaaaaa gaactatctg caccgcctaa accattgtca gaagcaagct
    16741 tgcttggtca aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca gagattatcg
    16801 agaaactaat caaatctgaa ctgatggaac gtacccctca aggattgcaa gtatctccta
    16861 aaggtaagca attattagta ttggtaaatc cctctttagt aacaccagat ttgacagaaa
    16921 gctgggaaaa agaccttgaa gctattgctg caggaaagaa acaagcagga accttcttga
    16981 atggaatcga aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc aaacaagaat
    17041 atcaagattt ctcgattacc caaaagaaat gcccagaatg tggggccaat ctgcgcgaga
    17101 aaaacacacg tgacggcaaa atctatgtct gcaccaattc agattgcaac taccgcagaa
    17161 gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa atggaaatca
    17221 tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga tggaacgaca gaaaaattgc
    17281 ttgataaaaa agagcagaag aagaaaatga ccaaacatga agaacgacgc ttgctgaaaa
    17341 aatatgcaca agcagaagaa ccagaagaaa gcccattagc agcagcacta aaagcagcaa
    17401 tgaagaagta ataagatatg aaagaggttg tgatagaagt ggtcagcttc aagaaataag
    17461 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgaagaa
    17521 gctacttctg gaacaccatt tattcggaaa aaaggactgt gacaagactt ttgtcacagt
    17581 cctttttcat ttaaaaaaat gtttacttca tttgacgtat attattggtg aggcttcaat
    17641 tcatttggct tcactttttc tgtttctctt atgatataaa caggacgctg tttcgtttct
    17701 aagaagattt tcccaatata tttcccgatg attccaagac ataacaattg gattccacca
    17761 atgaacagga agatcgagac catggaaggc catcctgatg taggatcacc aaacaacaat
    17821 gcccgcaaaa taatgaacaa aattgcaata ccagaaccga cacaagacaa agcgccgata
    17881 aatgaagcaa tcgttaacgg tgcatccgag aagttcacga taccatcaat cgagtagttg
    17941 aataatttcc agaaggacca agatgtttcg ccagccacac gttcgcggtt ttcataagaa
    18001 atatattctg ttttaaatcc gacccagcta aataatcctt ttgaaaatcg gttgtattct
    18061 gttaattcta ggacggcatc caccatttga cgagtcatca agcggaaatc acgagcgcca
    18121 tcgaccattt ctgtatcgct gattttattg atcaactggt agaatttttt cgcaaagaaa
    18181 ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg tgccgacaca atcgatatca
    18241 gaagtagtga tccggttgat catctcagga agcagttcgg gcggatcttg cagatcaaca
    18301 tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc cagcgtacag agccgcttct
    18361 ttcccaaaat ttctggaaaa tgagacaaag cggacataag gataagctga ggctagcttc
    18421 ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa taaacaaata ttcgaactca
    18481 tgggcacctt tgaatttttc aacctcatca aaaaaaagag gaacagtttt ttcttcatta
    18541 aaacatggga caacaattga tactttcatc gtttctatcc tttcaatcgt atgtttatat
    18601 atggtttaca ttcaaaattt aataaacctt aaataacacc tttaaaattt gattttacgt
    18661 aaaagaacag gtattctttt tgtaaactaa cgtatttagt ttaccatgtt tcctcggttt
    18721 atcaaacttt taagaacaat ttttattagt tggcaagtag ttttggatag agaaaaagga
    18781 ggaagttcca gtctattgac taggagcaaa caaaatgaaa atacacacac ctatcggctt
    18841 tttatggtta gatgcagatg aatccggatt gactgctgta tcttttcagc caatttcaga
    18901 aagcgaatca gcgaatcagc gaattttaac gcgcacacaa gaacagtttg aagaatattt
    18961 tgcgggaaaa agaaaagaat ttgatgttcc tttatctata aagagaggta cgccttttca
    19021 gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga gaaatccgaa cgtataaaga
    19081 agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg attgggcagg caaatcgaac
    19141 caatccattg ccaatcgtta ttccttgtca tcgagtgatc gggcaaaatg gaaaactgac
    19201 aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa cgccaattgt tgttgttaga
    19261 aggatatctg caaaattaaa aacagttgtg attcggacat tgttccatgc gagaatcaca
    19321 actgtttttt catgttcatt ctaaactttg atcagccaaa taaatagtaa agccatcact
    19381 gtttggagaa gcccgacagc taatccataa gataagaagc gtgtaccttc tttcatgaat
    19441 tttgcaaagt ctaaacgcag accaattgcc gctaaagcag tgatctcaaa ccagctgctg
    19501 ataaaatgtg ccgattggtc aataactaca ggtaaagaaa acaagctgtt gaccaaacaa
    19561 aagatcacaa accctaatac ataccaagga agcggtaatt ttcgtttttt ctgcgtatca
    19621 gttggcgttt caaacagagc tggttgtttc ttgtgcatga atttttcaaa cagatagaca
    19681 acaacaacga gcatcataat acgtagaatc ttaaatagca tggcgaattc gacaacagaa
    19741 ttgtcaagta agcttgcccc agcgactact tgaccaacag attggagtgt accacccaaa
    19801 agtgcacttt tttcaatgag atttccacca aacaactgta atccaagaaa agggagagtc
    19861 aacatcatca cagtacccag tagattgact agtgtgatga tctgtccttt ttcttcctct
    19921 ttcgcatgga tggaaggggc gattgaagca atagcagaag aaccacaaac agcgtttcct
    19981 ccagccatca tcaaagaaga agtatcgctg aattgcagtt ttttaccaat caagtaagca
    20041 ccgatgatag tgactgacat ttgcagtaac acaaaaacaa ttccttttac accaatttga
    20101 gcaatcgttt gagctgtgac agttgcacct agtaaaaaaa cagagaattc taatagtttg
    20161 ctttcagcaa attttgtgcc gattgctaga acaggctgtt taaaaaaagt atttcctaat
    20221 aaaataccca ataaaatagc aatagtcgct ccacctaact gtggcagata aatagcaaga
    20281 agcctgctga aggcagcgat ggcaaaagaa agcagtaaac cgggtaagat ttcgcggacc
    20341 gctgaatcct ttacagattt tattggatgt gacaatgatt tcatttgatc ggttcctttc
    20401 gtcaataaat actaaaagca tactcgaaca tagtagcact aaaccagtat tttgacaaaa
    20461 gaacaagagg tcgtgacaaa agtcttgtac gacctcttgt ttcgaataaa cggtgttcca
    20521 gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    20581 aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt aaacggtgtt
    20641 caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac agctgttttt
    20701 gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt gaatcgatta
    20761 ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa ttaagaaacg
    20821 tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt ccgcaacttt
    20881 taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa cagtagtaaa
    20941 tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg gataaaaacg
    21001 aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt gagataaagc
    21061 gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat aacctgttag
    21121 gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat gagccatatt
    21181 tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc agatcaatga
    21241 aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta cagtgatgac
    21301 cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg aaagatcagc
    21361 tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga taacagcgca
    21421 cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat aagtacaaat
    21481 aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat catgcaacgt
    21541 ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca taagaatcat
    21601 agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa acagatttcc
    21661 aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt tcaaaaagtt
    21721 cttcatatat aatattctcc tttttattta atagatttta gtaccaagat gaacgaatac
    21781 attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt gtcttcatct
    21841 aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga tggttttttg
    21901 tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga agtggtgcca
    21961 tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt tccagagcag
    22021 cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag ttggagcggg
    22081 aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca actaagcaag
    22141 ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa actcagcaaa
    22201 aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc cacacctttg
    22261 ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct aaagtgcatt
    22321 ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa catgaatccg
    22381 attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac tctttgatgg
    22441 aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta agagaagcaa
    22501 actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc caagataaga
    22561 agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga atcggtcgct
    22621 cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg aatttccatc
    22681 gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta gagattgccg
    22741 aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag aatctcagct
    22801 ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa gcagtaggct
    22861 tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc ccaaatgtct
    22921 atggaaagac tttccattat ctaactggac cgctataata atcagcagta tggtttttaa
    22981 gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg tattgattat
    23041 ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt atatgtagca
    23101 cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca agttgtctgg
    23161 tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa atggatctgg
    23221 aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt gctcaaattc
    23281 tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt cggtgcgttt
    23341 actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc actgatcgta
    23401 actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg gctgattggg
    23461 aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga tgactttgga
    23521 acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg aatctcttgg
    23581 cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac gatcttcttg
    23641 gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc ttatcagttt
    23701 gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag ttatcagccg
    23761 gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt caacgtaagc
    23821 aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg tgaaaacttc
    23881 ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta tcgtatgatt
    23941 cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg tttgatcatg
    24001 atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact tcctttaaca
    24061 gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa catgatcggt
    24121 atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc ttcaaggagg
    24181 taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa aaagccaaag
    24241 cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa gaagtaccga
    24301 aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt cgcctgttca
    24361 acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc gagtttacgg
    24421 cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga ccactgatct
    24481 tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa ggagaactga
    24541 tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt atttaatgga
    24601 aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga catcacgttt
    24661 gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat cgaagttgaa
    24721 gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc ttctgttaat
    24781 gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa tgcgtggatc
    24841 ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca gaaaatcact
    24901 tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc tatatgaaac
    24961 gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc ctgtttgctg
    25021 aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc gagcgtaagc
    25081 aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag ctaagtccaa
    25141 gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac acggaagttc
    25201 aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg aaaaatcata
    25261 agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa agacattcaa
    25321 tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg aaaaagggga
    25381 tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc gtctcctgaa
    25441 tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata ttacaaaatt
    25501 aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc agcatttcaa
    25561 cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat tagctggcgt
    25621 accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg ggttagaagg
    25681 acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg tcggtatcgc
    25741 acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta gcgcattgga
    25801 cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga aattgaattt
    25861 gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca acaaagtcgc
    25921 tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct tcagacaacc
    25981 gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag ctgattcgac
    26041 agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa ctttgacctt
    26101 tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct ataacatcga
    26161 tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg gttcattgac
    26221 tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca tcaaagaaca
    26281 aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca tatctagatt
    26341 ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta tatatgacat
    26401 taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc ctttactcta
    26461 ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg atcatcagta
    26521 atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca tttactaaag
    26581 caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt ttatccgcag
    26641 caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct ggtgtactgg
    26701 aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc ttgatacctg
    26761 aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg atcggattta
    26821 ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg caggaaggct
    26881 accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta ctaatcgtat
    26941 ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga taataggata
    27001 tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc ttttgctgac
    27061 tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa ataaagcaga
    27121 cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt tggaacatgt
    27181 gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg atgactatgt
    27241 attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc agcatattcc
    27301 ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg gtgctgtcca
    27361 catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat taaaagatgg
    27421 tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca caattctaca
    27481 agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa cattcgatga
    27541 tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat cacttttagc
    27601 ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact tcgcttacgg
    27661 cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact ctccttacgt
    27721 gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa aactgattga
    27781 agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg gctctgttaa
    27841 accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa taagtctgta
    27901 atggcttatt tctcatcttt tttataccta ttctaattta gaaatcaaaa ttgtttaata
    27961 ataaataaaa gatatttgat tttagtaagg aaggtcattg cgcttcattc tcaattagtc
    28021 taaaatgagt gagaacgaaa gagaatttgg gggtataatg catgtctgtc ttagaaataa
    28081 aaaatctaca tgtgtcgatc gaggaaaaag aaatccttaa aggcgtaaac ctaacaatga
    28141 aaaccggaga aatccatgcc atcatgggac ctaacggcac aggaaaatct accttatctg
    28201 ccgctatcat gggcaatcca aactatgaag taacagaagg cgaaattttg tttgacggga
    28261 aaaatgtttt agacttggaa gtagatgaac gtgcgcgact tggcttattt ttagctatgc
    28321 aatatccaag tgagatacca ggtatcacga atgcggaatt catgcgtgca gcgatcaatg
    28381 cgaaacgtga tgaaaacgac aaaatttctg ttatggcatt tttgaaaaag ttagatgaaa
    28441 aaatggcttt actaaatatg ccagaagaaa tggctgaacg ttatctgaac gaaggttttt
    28501 ctggcggaga aaagaaacgg aatgagatcc tgcaattgtt gatgttagaa cctacatttg
    28561 caattttaga cgaaatcgat tcaggtctgg atatcgatgc tttgaaagtc gttgctaaag
    28621 gagtaaatga aatgcgcgga gacaatttcg gtgcattgat catcacccac tatcaacgat
    28681 tattgaacta tatcacacct gatgtcgttc acatcatgat ggaaggccga gtagtcatga
    28741 cagggaatgc tgacctagct aaacgtctgg aagcagaagg ctacgctggt atcagtaaag
    28801 aattaggaat cgactataaa gaagaagaag cgtaaggggg agcaagaatg aaagaaaaaa
    28861 actggctcga ttatcttgac gcggtaaatg atttttcttt aagtaaaggc gaacctgatt
    28921 ggatgagaac cttccgtcaa gacgcactag cgaaagcaga tgaactgcca ttgccgcata
    28981 tcgatcgggt gaaattccat cgctggtcgt tatttgatgt gaaagaaaca caaaccatca
    29041 gtgaaacagg cacgattccg gcatttgatg caatgaaaga caatcctgtg cttgtccaac
    29101 aaggttcatg gacgattttt gaacaactgc ctgtggaatt agcagaaaaa ggagtcattt
    29161 ttaccgactt gttcactgca atgatcgaat atccagaact agtccaagaa tattatatga
    29221 aaaaagcagt aaacatgaac gaagaccaat tgactgcact ccatgtagct tttatgaaca
    29281 gcggtatttt cctgtatgtg cctaaaaatg tcgtgatcga tgaaccactc gagtccttat
    29341 tcattcaaga tggcgcatcc gatgagcact tcttcaagca tgtgttgatc gtggcagatg
    29401 aacatagtga attttcttat ctggaacgtt tccagacaac caaagaacaa gtagcaaaat
    29461 catcaggtaa tatcatcgtg gaagtcatcg ctaaagctgg ttcaaaaatc aaatattcag
    29521 ccgtagatca attaggagaa aatattactt cttatatgaa tcgccgtggg cacattttac
    29581 gagatgcttc tgtcgactgg gcaattggtg tcatgaatga cggtcatgtg atcgctgact
    29641 ttgactcaga tttagcagga gaaggtgcac acgcagaagt caaaatcgtg gcaatcagct
    29701 cgggcagaca aatccaagga atcgatacac gagtaaccaa taaagcccct catacgatcg
    29761 ggcatatttt gcaacacgga gtgatccgag aaaaaggaac attgaccttt aatggtatcg
    29821 gccacatctt gaaaggggca aaaggtgcag atgcccaaca agaaagtcgt gtcttgatgc
    29881 tttctgataa agcacgtggt gatgcgaatc ctattctttt gatcgatgaa aacgaagtaa
    29941 ctgctggaca tgctgccagt gtaggacgag ttgatccaga agaaatgtac tatctgatga
    30001 gtagaggatt gcataaagaa gaagcagagc gcttagtgat tcgaggattc ctcggttctg
    30061 tcttaacagc aatccctgta gaacaagttc ggaaagaatt agtcgaagta atcgaaggga
    30121 agttgaatgg atgatcgatg ctaaaaagct acgcaatgat tttcctatct tatttcaaga
    30181 cgtcaatgat gaacctttag tttatctgga taatgcagcg acgacccaaa agccaaaaca
    30241 agtactccag gcattagcgt actattacga acacgataac gccaatgttc atcgcggtgt
    30301 ccatacgtta gcagaacgcg cgacccatga ttatgaacaa gcaagagaaa aagtacgggc
    30361 gttcatccat gcaaaagaaa cagcagaagt gctgtttact cgtggtacga cgacaagctt
    30421 gaattgggta gccagaacct tcggcgaccg ctatatcaaa gcaggagacg agatagtgct
    30481 ctcttacatg gaacatcatt ctaatgttat cccgtggcag cagttggcaa aacgaacagg
    30541 tgctgtcttg aaatatatcg aactaacaga agaaggcttc ctggatatgg aggatgcagc
    30601 gaaaaagatt acggacaaaa ccaaaatcgt ctccattgct catgtatcca atgtcttagg
    30661 tgtcttcaat cctgttcaag aattagctga acttgtccat gaaaacggcg gggtcatcgt
    30721 agtagatggt gctcaatctg ccccgcacat ggccattgat gtccaagcac tagactgtga
    30781 tttctttgct ttcagcggac acaaaatgtg cggaccaaca ggtattggtg ttttatatgg
    30841 taaacgaaaa tggttagaag aaatggaacc tgttgaattt ggtggcgaaa tgatcgattt
    30901 tgtcgaatta tacgacagta catggaaaga actaccttgg aaattcgaag cagggacacc
    30961 aaatatcgcc ggcgctatcg cattaggcca tgcaatcgat tatttgcaaa aactcggtat
    31021 ggacaatatc catcgatatg aagaagaact agccgcttat gtgttgccaa aattacaagc
    31081 aattgatgga ttgactgttt atggtccaca agacccgaat tttcggacag gagtcgttgc
    31141 attcaatttg gatgggttac atccccatga tgtcgcgaca gctttagaca tggaaggggt
    31201 agccgtcaga gcaggtcatc attgtgcgca accgctattg aagtaccttg aagtatcagc
    31261 gactgctcgc gcgagctttt atttctacaa cacaacgcaa gacgccgacc gtttagttga
    31321 agcaatcatg gcaacaaagg agtttttcca acatgggact atctaaatta gacaatttat
    31381 accgtcaagt gatcttggat cattcttccc atccgcatca tcgtggaagc ttgactgact
    31441 cgacaagcaa gatcgaattg aacaacccca catgtggaga tgtgatcgaa ttgcaagtcg
    31501 atgtaaaaga cggaatcatc aaaaatatcg cctttgacgg cagtggctgc tccatcagta
    31561 cggcaagtgc ctcgatgatg acagacgccg tcatcggaaa atcaatagaa gaagcagaac
    31621 atttaactgt agactttcta cagcttgtcc aaggaaaaga agtcaaagat cccgaccaat
    31681 taggcgatgc tgctatgctt ggtggtgtag ctaaatttcc cgctcggatc aaatgtgcga
    31741 cacttgcctg gaaagcacta ggaaaagcaa tggaaaacga tggtaccgca gctttccatc
    31801 attaccacaa ggaagaggag tgagaacatg ggcgtaccag aattagaaga atataaattc
    31861 gggtttcacg atgatgtcga accggttttc agtacaggag aaggcttgac agaagaagtg
    31921 atccgtgaga tgtcaagaat caaaggcgaa ccagaatgga tgcttgaatt ccgtctgaaa
    31981 tctctagaaa catttaacaa aatgccaatg caaacatggg gccccgacct ttcagacatc
    32041 gatttcgatg ccatcaaata ttaccaaaaa ccaagtgaca aacccgctcg tgactgggaa
    32101 gacgtaccag aaaaaatcaa agatacattt gaaaagattg gtataccaga agctgaacga
    32161 gcttatctag ccggtgcttc cgcacaatat gaatcagaag tcgtgtacca taatatgaaa
    32221 gatgaattcg aaaagttagg aatcgtcttt actgacactg actctgcttt gaaagaatac
    32281 cctgaattat tcaaagagta cttttcaaaa cttgtaccgc caaccgacaa caaattagca
    32341 gcgctgaatt cagccgtatg gtcaggtggg acctttattt acgtgccaaa aggcgtcaaa
    32401 gtcgatgttc cattacaaac gtacttccgg atcaatgcgg aaaacacggg gcaattcgaa
    32461 cgtacgctga tcattgttga cgaaggagca agcatccact atgtcgaagg ttgtacggca
    32521 cctacttatt caagtaacag cctgcatgcc gccatcgtag aaatctttac aagaaaagat
    32581 gcgtattgcc gttacacaac gatccaaaac tggtcagaca atgtgtacaa cttagtaacc
    32641 aaacgagcaa aagcatacga aggcgcaacc gttgaatgga tcgacggaaa cctaggtgca
    32701 aaaacaacga tgaaataccc aagtgtttac ttagatggaa aaggtgcacg aggcaccatg
    32761 ctctccatcg cctttgcagg agcaaaccaa atccaagata cgggtgcaaa aatgatccac
    32821 aatgcaccaa atacatctag ctctatcgtc tctaaatcaa tttcaaaaga cggcggagaa
    32881 gtaaactatc gaggacaagt aacctttgcc aaaaacagtg cgggttcgat ctctcatatc
    32941 gaatgtgaca cgatcatcat ggacgaatgg tcgaaatccg atacgatccc attcaatgag
    33001 atccacaaca gccaagtctc tttagaacac gaagccaaag tctcaaaaat ctcagaagaa
    33061 caactctact atctgatgag ccgaggcctg accgaatctg aagcaactga aatgatcgtc
    33121 atgggctttg ttgaaccatt caccaaagaa cttccaatgg aatatgcagt cgaactcaat
    33181 cgattgatca gttatgagat ggaaggcagt gttgggtaaa cctgttatag gagctagaac
    33241 ccttgatata taagggttct agcttttttg ttttgcctgt atactagaaa tgaccagatt
    33301 ttgaccagct cttttactga tgagccatca tatcagcaaa gtcttgacct gttttcttag
    33361 gtgcattatt tgtaatatgt gcatagatgt ctaatgtcac tttactattt tcatgcccta
    33421 atcgttgttg aactaccttg acagattctc ctgcttctaa taataaacta gcatgtgtat
    33481 gtctaaaccc atgaggtgta atacgaggca agttatattt tttcaaaata tatcttaacc
    33541 aatcattaac agtgtttgga atgtatagag tgtttttaac tgttgtaaaa acatgttgct
    33601 ctttagagct agtattgtat ccaagtttta aatactcttc tttttgctgt aatttccagt
    33661 tgttgaggat agaaagagtc tcagtatcta aagagataac tcgtctagaa gctcttgttt
    33721 tcggagattg aattataact ttaccaaatt catctacagc aagagtttta ttgacatgta
    33781 gttctttatt aaacgtgtct atgtctttcc actgtaaagc gagtacttca ctctttctca
    33841 tacctgtgta tgccaataat ctgaagaagg cgtattgttt catgttacca aaatctttaa
    33901 aagcatccag taaattatta agctcctctt ttgagtaaaa tttacgattt ttctcatact
    33961 ctttttttcg tggaagaagt gttttttcca taggattatt gtcaatatat tgcattgcaa
    34021 ccccgtagcg taaaatttgt gcagtctgtt ttctcatata atcgtaactt tcatatttac
    34081 tgtgccattc atctaccact ttttgacaat atgggacaga gatattcgat agtttaagct
    34141 taccaaatgc tggaagtatt tgattatttg cgtatcttac tgagattgcg attgttgaag
    34201 ctttaacact ggtacgctga tgagttatcc attcattata caggtcttca aatgtcatat
    34261 caggtgcttt ctttttaaca ccgtataata tttgatgtct gtactcgtca taatcttttt
    34321 gagcttcttg tttgctacta aaacctcttc tcgtagtatt tattttttca ccagttcgtg
    34381 gatcggtggc aatgtgtcct ttatacatcc acgccacttg accgtttttc tttttgtact
    34441 ttgatatttt tgccattaaa tcatctcctc ttagtttaca aggagtactt accactagat
    34501 ggtatcacct cccttcattt ttttcttagt gtattttttc ccaattgatg aaatcgtttg
    34561 ttctagcttg tttatattat cagtaatttc tctcacagct tcttcgggat aagacatgtc
    34621 tttcaattga ataggtagcc attcatctac cattctttct agtagttctt ctatactgct
    34681 agtgaggaaa agaatgttat tgtcaaattc ttctacaata gcattgatga ataattcttc
    34741 tatttttaag atattgaaaa gactaatttt ttcattttta actttattac aagtcttgtt
    34801 agcaataaat tcttgcatct ctggttctaa tttggaatat ctatccagcc atgtatctaa
    34861 attagagtgt actggtggga actgttgacg aagatgctgg aacaggtttt tatctggaaa
    34921 tgttatacca tctagtacaa tgctatctct ataaagaata attcccaaaa tatattcttc
    34981 tacattgcca caaactaact cctctatact catatttccc aaatcagcaa ttcgggataa
    35041 tcgctctggt attggtaaat aggttccctt ctcccattcg tagatagttt ttttgtcaat
    35101 taattgaccg ttgttaatca taagaccaaa tgctggttgt gttaattttt tactctttct
    35161 tatagctttt atttttgttc cgagtatctt ttttcgttct aaataattta ttggtggacg
    35221 ttttatcata ttgaccacac ctcctaaaat tagtatacct caaaaaaggg gtgttgtaaa
    35281 taaattttac aaagctgttg acaccccttt tttatcgagg tattatgtgt atgtcgatga
    35341 actggtaatc attttttgtt tgattaatcg gttaataaca aaatactttt attttgagca
    35401 aaaaatacga agataattct tagaaaattt gttcaagcaa tcacgaaagg agggggaaat
    35461 atgtctctac aaatcattga tagcattgtt tctatacaag ttgaacaaca agtgaaagag
    35521 ataattacag tgctaaagcc tatgctagaa gacattattt ctggagtcac tctagagtat
    35581 atggactatc agcaggcaag tgaatatcta ggtgtatcag taggaacgat tagaaaatat
    35641 gtttctcaat acgggttacc tgttataaaa attgatacgg tcattagatt taaaaaatct
    35701 gatattgata gtttcatgga acggtataaa ggttgagtaa acaaataaga ctaaaacata
    35761 tagtaataaa gagtttgttt ttattatctg tatgttttag tctttaacag aattttataa
    35821 ggaggaaaca caaatggaaa catcaatgat taatattcca atttatgtag atcaagaaaa
    35881 attattagag aagccagtta caaaaaaaga aaaaactgat gtaagagata ggtgtttaga
    35941 taactataga gaagttacaa gagatgagtt tgtagagata ctaaattcat cacaatcatt
    36001 tattccaagc aagacaaaga ataaaggcaa tgacaaggag agttttgtgg aaaccagagt
    36061 aattattctg gatgtcgata acactgttaa agatgagaag gggaaggtag tagatttgag
    36121 taaagatgat agtagatact taagcataga aaaggtttta tctatcaatt tagttcataa
    36181 ttctgcgttt gcgatacaaa aaagtattcg gtactctgaa aatctagaaa aatacaagat
    36241 tgtctttcta ttaaaagaag caattactga ctatggtaaa atggttgctg tttacgaata
    36301 cttgaaaaag aacatccccg ggtgtgatga caatgtaaat gcttcgaata gaatgttttt
    36361 tggaggatat aagtcagatg cagtgataat aattaatgaa gacaacatgt tagatattac
    36421 tgagcttccg attgatttta ccatgacatg ttctaaaaat tgtcaaagtg attcagggag
    36481 agagtatgaa ctagtcaatg aaaccgattt tgttaagttg ataaaaaatg acgacaaaga
    36541 agaaatgaaa cagtggttta aagactgcct gtttgattcc tccgacatgt cttttaatga
    36601 gatttatgaa agattgttaa ccattgatat gaataaatta cttaagtcaa gtaaaaactt
    36661 aagatgtctg tttcacaacg atcataatcc ctctgctagt atttttacca gtaaaactgg
    36721 gcattccatt ttttattgtc attccagtaa ttgtgatatc agtgaaaatt ttattggagt
    36781 tgtgatgcta attttaaaga aagacagtcg ggtagaaaca tttaattggc tattagagaa
    36841 cctagacttg tatcctacac attttcgaaa attgaaagag gaatcaaaag tactttttga
    36901 cactcttgaa tcaatgaaag acaaactttt caggacaata aggaattatc tagaggaaat
    36961 gcgacgtgtc tatgatgtct tgctttctga tgttaatttt tttgatgata gtaaggaaag
    37021 tgtgacttgt attttgtcgg gggaacaatt agctaaaaaa atgagttctt actatggtaa
    37081 aacttatgac atagataaat gtaataagtt actatcactt atgactttta taggattgat
    37141 aaaaaaatta gatgatgaag atgttccttt gaagatgctc gaatacctaa ataggttaaa
    37201 ggaagagaaa gcgttaggaa actttaatca taagagaagc aatgtctatc gattagacgt
    37261 ttttaatgca acttctgtga ttcaaaaatt gaatgaagat atccttccac ttctggaaaa
    37321 aattcatttt acatatcaat atttttctta tgaatgggtt aagatatgtt ttaacgaaaa
    37381 agaggctaaa agagtatttc ctcaaaattc ccgatcagaa ctcagcaagg aaaaacaatt
    37441 gattttagat gaagcacatg aagttttaca gggcttatcg tggcaaggga catatctaat
    37501 gacagagaaa gaacttatta acactgtttg tgaacgccta cgtaatgttg gggataacag
    37561 cgtgaaaaat gctttaataa aaaacagagg ctactttgtt aaacaaggat tcactcttga
    37621 acgagcttct aaggatatta agaaactata caatgtgaaa gcaagtagta gttttttaat
    37681 atatttagcg aaaggggcag ggatagatga aacaataaaa gaattgatat tatcaggagc
    37741 tgggatagtt cctctgtatc aatttacaag tgtaacaaga gatgatggac ggagagtaag
    37801 gaagagaaaa gacccaattg tattaaacta gacaggttat ccatagctct taatcttatt
    37861 tcatctcaat acacccaccg ttaaagttcg gtgggttatt tatttttcaa tctttcaata
    37921 gctgattgcg ttcattttct tgccttttta atagcttcat atagtcaatt gttcgaactg
    37981 catcttcagt gctaagagaa cgatagagag ccaaaaactc ttcctcataa tctacgacaa
    38041 cattgtctag aaaatggctt acaggggttc ctagggctct agaaagagct gttaagctat
    38101 cgaggttagg ctctgttaca gaattttccc atcttgctac tgcctgttgt gtagagaaga
    38161 ttttttcagc taattctttt tgtgtccacc cgagagcttt tcgcttttct ctaatgacct
    38221 ttgcatattg tttctgtttc attaatacac ccccatctca gtatagtaca acaagttgtt
    38281 gtatttgtaa tggtatttga agttttttat attttatgag ttgaaataca tcatattgtt
    38341 gtatataata aaacaggagg ggagaatcat gaaaaaagta aataatctca gccgatacag
    38401 aaaagaaaaa ggactttctc aaacggagtt agcaaaaaaa atgaatgtta cacagcaatg
    38461 tgtaagttcg tggcaaacag ggagaacgat tcctaaaccc tatcaaatga agatgctttc
    38521 tgagatatta agtgtaccaa tgaatgagct gttttctgat gtatttaata aagtaaacag
    38581 ttaactaata agcaattgaa tgattttagg aggagaagac atgtattgta gaaaatgtgg
    38641 caaagaaata acagatgaaa gtaagtattg ccagttttgt ggagcactac aagaaacaga
    38701 tgagacaacc ggaacagaca cagtaaagaa aagtactgag cagacaatta atgaaatgaa
    38761 ggaacaaatc gtacatggac aagagacagg gaagctgtat ttgattattg gttggatttc
    38821 tatggtagta tcgttagcat ttattcctgt tgtatttggt gctgttgctg ttattatggg
    38881 ctacttatat cgagaaaaag atgagaaaat gggtacgatt ttgatgatag caggggtagc
    38941 tggagcaatc tttggtgtac ttttagggat gtcaatgtac tgataagagg gataagaaca
    39001 aattattttg gagataggag ataaaaagtt gaataaagta aatatgaaca agaagtttgt
    39061 cattataggt attgttgtct tggctattat aggtattatt ttttcaaaaa tgacaggtac
    39121 atctggatta gagaagtcat caaaaccatt ggtaacacag attttacaag aacagtacaa
    39181 cttaaatcga tcatgtgatg atgtgacgat tactcatgaa aatggagata acacataccg
    39241 ggctaaagct atattagaca atggaagtgc tatcaacata aatattgagt actatccaaa
    39301 gaaagaccgt atatatgtgg agataccata tgctgaggtg ttaatgttaa attgatttaa
    39361 atgtattatg cataccgtcc aaacaggaac tcccaaaggt gtaaattcac tagggagttt
    39421 ttatagtttc ctataaatta aatactaata caggtgacaa aaaaatatta caatgattgt
    39481 cgggaatttt tatgttattc actgttataa caatataaaa gaaatgaaaa agaaaaaatt
    39541 attatggata tgtttggtat ttttattgat aattggtgga attg
//
LOCUS       DBGZHO010000019        38514 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.019, whole genome shotgun sequence.
ACCESSION   DBGZHO010000019 DBGZHO010000000
VERSION     DBGZHO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.019"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(78..770)
                     /locus_tag="ACN3HL_001189"
     CDS             complement(78..770)
                     /locus_tag="ACN3HL_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HHC8006079.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1165..1788
                     /locus_tag="ACN3HL_001190"
     CDS             1165..1788
                     /locus_tag="ACN3HL_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHC8006080.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(1872..2594)
                     /locus_tag="ACN3HL_001191"
     CDS             complement(1872..2594)
                     /locus_tag="ACN3HL_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HHC8006081.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(2584..3321)
                     /locus_tag="ACN3HL_001192"
     CDS             complement(2584..3321)
                     /locus_tag="ACN3HL_001192"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006082.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(3333..4325)
                     /locus_tag="ACN3HL_001193"
     CDS             complement(3333..4325)
                     /locus_tag="ACN3HL_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006083.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(4340..5083)
                     /locus_tag="ACN3HL_001194"
     CDS             complement(4340..5083)
                     /locus_tag="ACN3HL_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006084.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(5157..5261)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5324..6646)
                     /locus_tag="ACN3HL_001195"
     CDS             complement(5324..6646)
                     /locus_tag="ACN3HL_001195"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHC8006085.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(6633..7598)
                     /locus_tag="ACN3HL_001196"
     CDS             complement(6633..7598)
                     /locus_tag="ACN3HL_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006086.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(7595..9133)
                     /locus_tag="ACN3HL_001197"
     CDS             complement(7595..9133)
                     /locus_tag="ACN3HL_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HHC8006087.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(9549..9836)
                     /locus_tag="ACN3HL_001198"
     CDS             complement(9549..9836)
                     /locus_tag="ACN3HL_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006088.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            9970..10638
                     /locus_tag="ACN3HL_001199"
     CDS             9970..10638
                     /locus_tag="ACN3HL_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8006089.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(10929..11669)
                     /locus_tag="ACN3HL_001200"
     CDS             complement(10929..11669)
                     /locus_tag="ACN3HL_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006090.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(11799..12746)
                     /locus_tag="ACN3HL_001201"
     CDS             complement(11799..12746)
                     /locus_tag="ACN3HL_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006091.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(12875..13639)
                     /locus_tag="ACN3HL_001202"
     CDS             complement(12875..13639)
                     /locus_tag="ACN3HL_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHC8006092.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(13643..14032)
                     /locus_tag="ACN3HL_001203"
     CDS             complement(13643..14032)
                     /locus_tag="ACN3HL_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006093.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            14167..14709
                     /locus_tag="ACN3HL_001204"
     CDS             14167..14709
                     /locus_tag="ACN3HL_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HHC8006094.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            14857..15489
                     /locus_tag="ACN3HL_001205"
     CDS             14857..15489
                     /locus_tag="ACN3HL_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006095.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(15623..15748)
                     /locus_tag="ACN3HL_001206"
     CDS             complement(15623..15748)
                     /locus_tag="ACN3HL_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HHC8006096.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(15882..16775)
                     /locus_tag="ACN3HL_001207"
     CDS             complement(15882..16775)
                     /locus_tag="ACN3HL_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HHC8006097.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(16957..17883)
                     /locus_tag="ACN3HL_001208"
     CDS             complement(16957..17883)
                     /locus_tag="ACN3HL_001208"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HHC8006098.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(17968..18729)
                     /gene="pflA"
                     /locus_tag="ACN3HL_001209"
     CDS             complement(17968..18729)
                     /gene="pflA"
                     /locus_tag="ACN3HL_001209"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HHC8006099.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(18973..21204)
                     /gene="pflB"
                     /locus_tag="ACN3HL_001210"
     CDS             complement(18973..21204)
                     /gene="pflB"
                     /locus_tag="ACN3HL_001210"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HHC8006100.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(21481..23931)
                     /gene="parC"
                     /locus_tag="ACN3HL_001211"
     CDS             complement(21481..23931)
                     /gene="parC"
                     /locus_tag="ACN3HL_001211"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HHC8006101.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(23943..25988)
                     /gene="parE"
                     /locus_tag="ACN3HL_001212"
     CDS             complement(23943..25988)
                     /gene="parE"
                     /locus_tag="ACN3HL_001212"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HHC8006102.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(26154..26588)
                     /locus_tag="ACN3HL_001213"
     CDS             complement(26154..26588)
                     /locus_tag="ACN3HL_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HHC8006103.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            26715..27353
                     /gene="plsY"
                     /locus_tag="ACN3HL_001214"
     CDS             26715..27353
                     /gene="plsY"
                     /locus_tag="ACN3HL_001214"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HHC8006104.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(27485..28360)
                     /locus_tag="ACN3HL_001215"
     CDS             complement(27485..28360)
                     /locus_tag="ACN3HL_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HHC8006105.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(28442..29233)
                     /gene="codY"
                     /locus_tag="ACN3HL_001216"
     CDS             complement(28442..29233)
                     /gene="codY"
                     /locus_tag="ACN3HL_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HHC8006106.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(29251..30651)
                     /gene="hslU"
                     /locus_tag="ACN3HL_001217"
     CDS             complement(29251..30651)
                     /gene="hslU"
                     /locus_tag="ACN3HL_001217"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HHC8006107.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(30665..31213)
                     /gene="hslV"
                     /locus_tag="ACN3HL_001218"
     CDS             complement(30665..31213)
                     /gene="hslV"
                     /locus_tag="ACN3HL_001218"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HHC8006108.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(31250..32155)
                     /gene="xerC"
                     /locus_tag="ACN3HL_001219"
     CDS             complement(31250..32155)
                     /gene="xerC"
                     /locus_tag="ACN3HL_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HHC8006109.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(32353..33729)
                     /gene="trmFO"
                     /locus_tag="ACN3HL_001220"
     CDS             complement(32353..33729)
                     /gene="trmFO"
                     /locus_tag="ACN3HL_001220"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HHC8006110.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(33698..35776)
                     /gene="topA"
                     /locus_tag="ACN3HL_001221"
     CDS             complement(33698..35776)
                     /gene="topA"
                     /locus_tag="ACN3HL_001221"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HHC8006111.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(35898..36755)
                     /gene="dprA"
                     /locus_tag="ACN3HL_001222"
     CDS             complement(35898..36755)
                     /gene="dprA"
                     /locus_tag="ACN3HL_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HHC8006112.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(36811..37578)
                     /locus_tag="ACN3HL_001223"
     CDS             complement(36811..37578)
                     /locus_tag="ACN3HL_001223"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HHC8006113.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(37571..38431)
                     /gene="ylqF"
                     /locus_tag="ACN3HL_001224"
     CDS             complement(37571..38431)
                     /gene="ylqF"
                     /locus_tag="ACN3HL_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HHC8006114.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT        10463 a         8145 c         6567 g        13339 t
ORIGIN      
        1 ttgtactcca aaactgaact acttagtata gattactgtt gcttctttac taatttaggt
       61 ttacttgtta agaaagatta tttacgcaaa tgttcttcaa caatttgctg agatttatca
      121 gctgtatctt ccacttcatc ttttgctttt tctaactttt gaatatattg tttcaagctt
      181 gagttttcag cagttgcttc gtctaatttc ttttgtgtat ctgttaactg agtttctaca
      241 tttgtttttt cttgtgtcag tgttgcgatt tgttgattca aaccatttac agtattttgt
      301 aattctgaaa gttttgcttg tgcttcttgt agtcttgctg tccaatctgc attcagatga
      361 ttgatttcat catttttttg gttgatctca tctagtttga cattgatttc attttgtttg
      421 ctttgtagtt gtgcatcctt gctgactaat tgactttcta agttttgttt ttctgctgcc
      481 gattgatttt tttggttttc taattcattt acttttgttt ggtattcttg gacatctgcc
      541 tttgaatctt gcaatgtctg ttctttttgt gctagtcgag cggtaagatc tgtaatcgct
      601 tgctctttat ctgtcaatgt atgatcaagc tgtgtcagat tctcattgat tgtatcaata
      661 tctgtctctc caccccacaa aataatttca tttgcgtacc gcgtgcctgt gtagccaatt
      721 agacatagaa atgcaacgac aatcccacca gtaataaatt tctttttcat ttgcatagct
      781 ccttaatcca atacttttac atgctaaaag taagtgatct caaacacaat gtcaagcgtt
      841 tttaaattac atatgtaatt ttaatataaa tactatcaaa tactcattta atcctccttt
      901 tttatctatt taaaaaatct tttttataga gaaaaatgca ggttaatact ttcttaaata
      961 aatatttatg gtgaacaaaa acaaaaaagc aagttttatt aaacgtaacc cttttcattt
     1021 catagattac tgtatttatt acaaaaaacg cggatttgtc ataaattgtc atgcttcttt
     1081 tacctatgaa atattttcac gtgttaaagt attcctcgtt gaacacaaca aataaaactt
     1141 tttaacgaat aaaggagatt tttcatgaca tcacttaaaa ctttactttt tggaacaact
     1201 ttggctgccg gcgctgcatt cttcatggga acgactgctc atgcggacga agcttatacc
     1261 gttcaatcag gtgatactct atcaacgatt tctcaaaaat acgttggtga taactccttg
     1321 atcaatgcca ttgcagaatc aaattcaatt tctgatatta acctgattta ctcaggacaa
     1381 caattaacaa tcccaacaga aggctctgca caagcagctg ctgaacctca agcagccgtt
     1441 caagaagcac cagtccaagc tgaacaacct gttgtacaag aaacggttca aacggaaaaa
     1501 caagcagcgc ctgttgctga aacacaacct gctcctgctg taacagaaac tgctgctact
     1561 ccagcaagca caagctctgc aaaagaatgg atcgcacaaa aagaatcaag cggttcttac
     1621 acagcaacga acggacgtta catcggacgt taccaattag attcttctta cttaaatggt
     1681 gactactctg ctgcaaacca agaaagagta gcagaacaat atgttacttc acgttatggt
     1741 tcttgggaag cggcgaaagc attctgggaa gcaaacggtt ggtactaaga ttcatttatt
     1801 aatcaaacag tttactttta tacaaagaaa gccaaaaaga ggtgcgacac tagttgtgtc
     1861 acatctcttt tttatttacc taatctaatg aaacgttcca agttttgata agtatttttt
     1921 ttaacttctt caactgatag ctctttgatc tcagcgattg tctttaactg ttcttcaagc
     1981 agtgagacat aatctttttc tgaaaaaatc ccccctaaag cccactctgc tgcatgtagt
     2041 ccatccgttt caataagtaa gtggtcgatt gggactgctt tagctagttg ccagactgct
     2101 ggattctttt tcaaatcaag accaatgctg aaataacagc ctaaatcaat atagtcttgt
     2161 tgatagtcca aagaagaata ccaatggatc aaatagtgat tagggtaagc ttggatataa
     2221 tttaagatct ctttttcgca tccttttgtg tgcagtacaa caggtttctc atttatggct
     2281 gcaaaagcaa gctgtcgctc aaatactttt ttttgtgtag tcatcggtac attcgtccaa
     2341 atattatcta accctatttc accgatgatc cttgcttttt tcaaaaaagg ctcaacttgt
     2401 tcaaacgtat agctatctgc tttccaagga tggataccgt aacttaaggc ttgagtctta
     2461 cttgctgcaa gctgtctgtt ttccttccat tcttctggcg aatcacaatt gatgatcgtc
     2521 aaaatcgtgt gttcctgctg aaggagtgct aaactctgac tcccatctaa atgacaatga
     2581 gcatcactta acatctaatt cacctgccaa taactgataa atcgtttgct tcaactctga
     2641 ttgctgcagt agccattcac gtgaccgtcg tttttcaggc acttgaatct cagcaatcac
     2701 atgtgccgga cgggcggaaa gcacaagaat cctgtctgat aaataaattg cttcttcgat
     2761 atcatgcgtc acaagtaaag tagtccgctt tgctttttta ggcagcttca acatccagtc
     2821 ttgcatctgc cctctggtca tagcatctaa cgctccaaat ggttcatcaa gaagcaagta
     2881 agaagaagga ttcatgattg ttcgtaacaa ggccgttcgc tgcttcatcc cgccagataa
     2941 ttgttccggc aaaaaatgtt catagccgtt taacccaaag atatccagat aatcccttac
     3001 ttgttcttca ttgattgtta gatgattgat tttttgatat aacgtaacgt tttgatagac
     3061 gctcagccaa ggaagtaaca tatcttcttg cggcatataa ctaaatgctg tatggagacc
     3121 agttactttt tgatcgtcta ctttgatcgt tccagaagtc ataggctgga ctcctgttaa
     3181 agttttcagc aatgttgact taccggctcc gcttggcgcg acaatcgatg taaaggtatc
     3241 tttagggata gtgaaatgga tgtcttctaa tattttcagg ttttcaatga ctacattcaa
     3301 gtggctgatt tggattgaca tatctatcac tcctatttta taaactgatt agtgaatagt
     3361 tcttgcgaag gtacatcttg cttgatcaat ccgttttcct gcataaaagc tgtataattg
     3421 cgccaaactt tttcttccat caatccccaa ttctcaggat catccgtata attttttgac
     3481 aagaatgctt gtgattcttc taaaaacgtc cgatcatttt cttttgcata tttttgcaac
     3541 agtttagcac tgtcatttgg atccttaata gcttcctgat agcctttttt cgtggcatcc
     3601 ataaaagact gtaccaattc tggatcactt ttgatcagtt gatcattcgt aataattacc
     3661 ggagtatagt aatctaaccg ttcatctaat tctttcaatg ggatatagtt tagttcaata
     3721 cccgcttctt ttgctttgat catatcccaa ccttcaaagt accattggat atctgaggat
     3781 tttcctaagc tttctggccc ttctccattg cttcctacca ttgtcagttt tgaaaagtcc
     3841 ccgccgtctt tttccatcac agcttttaag acagcttctt cacttggact ttgccaacct
     3901 gcatatgttt ttccttcaaa atcttttggt gaatggatgt tactgtctga tagggtggcg
     3961 aatccagaag tattatgttt gatcactgta gcaattgctt tgactggtat attctgtcca
     4021 tctgcgtgag cataagtgac atcttcttga taacttacac caaattgtgc tttgtccgca
     4081 cctactagac caatacttgt cgaattatct cctggttcga tgatttggac atttaaacca
     4141 gcctctttat aatagccttt ttcttttgct aggtagatgc cagtatgatt agtattcggt
     4201 acataatcca aaacaagtgt cacttttttc aaatccttta tttcttgttt gctacttgtt
     4261 tcttttgcag tgccacaagc ggataaaagc aacagtagcg gtaataaaag ccataatttt
     4321 ttcatttgat ccccttctct taaaaaatat aaagcatacg ataataccct tttttcaata
     4381 atgaacaagc gccattcagc aataaactca atagaatgac acaaatgatc gcagcaaaaa
     4441 ctttatcgat ctggtagctg ttttttacgc gtatcatgta ataccctaag cctgcttgag
     4501 cgcttagcca ttctccaacg actgctccgc tgacacaata agtagcagcc acttttaaac
     4561 cggaaaagaa gccggataaa cccgctggta ttttatatat tcgataaatc ttccctgtat
     4621 ctgcccccat cgttttcaaa aagatgattt gctcttttga tactttcctc aatgtatccg
     4681 aaaaagaaac tacgatcgga aaatagctta tcaagacaac aaggatcact tttggaagca
     4741 taccgaaacc aaaccatagg gtaagtaatg gccctaacac catgattggc aacatttgtg
     4801 aaatcactag taacggataa aaagacattt ctaaaaactt ccaataatcc attgccaagg
     4861 cagtaataaa agaaagaacg ctagctatta ccaaaccaag cactgcttca tttaatgtcg
     4921 tgacagaatg ggaaagtaat acttgtgcat ctgccgctaa tgcagaaaat acagcagcag
     4981 gtccgggtaa aataaaggca ggtattttcc aaactatgac aacaatctgc caaataatta
     5041 aaatgaatgc catactgact gctggataaa gatttttctt cattttgtta cctcctttct
     5101 tctaatatga ataacaaaaa acgcttgaaa tgggcacgac atagtaaccc gcttcaagcg
     5161 tctgctatgt ttctcccttc accagtatta actgacaggt tcaatgggtc taagttcaca
     5221 acttactctc atgtcgtcta cgacatcccc agaaacaggt attcattttt taaagtgtag
     5281 cacaagaagg aaaaagcaac aagcgcttta gttatcatgc tgattatttc aataaatagg
     5341 agagatcact tgccaatgtc ggatacccca tgatatagct atccaactct tttttagtca
     5401 atttttgatt gatgacgagt gtcaaatcat cgatcaattc gtctgcttgc tcgctaatca
     5461 ctgcagcacc aatcaaataa ttttgctggt caaaggtcaa ttcagcctta gcaactggtt
     5521 cattgacacg atgataggtg aaccaactgg taagatccat ctctaccact tgatctgacg
     5581 aagaggcgtg actttttgta actcctactt cagcaagttt aggactggcg tagacgatcg
     5641 taggtataat cggatatttg ataggttcgc ttgttgcatc cgttatccgc ttagctacat
     5701 aatttccttc aaaagtggcg actggtgtca attttggggt tttccttgaa acaatatctc
     5761 cacacgcaaa aatttttgga ttgctcgttt gcagataatc attgactgca attccgtgtt
     5821 tatcaaagac gatattcgct tgctcaagtg ctaaagattc tgtattcggc tgtctcccag
     5881 tcgcacaaaa aatcatatct gctactaatt ccgtctcttt tccgactaaa cgatagcgag
     5941 taccttctga aatgatcttt tgggtttcaa caccaaaagc aaactgaatg ccagatgctt
     6001 ccatttgatg gacggcttcc tctaccaaag acgcctcaaa ttcttttaat ggccgttgat
     6061 tatgatggac aatggttact ttgctccctg cagcattggc aatcgtagct agctcaaaag
     6121 caatataacc accaccgata aaaatgattt ctttaggcag tacaggcaat gataaaaagt
     6181 ctgcactagt tttcaagtat tcctttccct ccactggtaa gatcgtaggt ctttgcccgg
     6241 ttgccaaaac taagtaatcc gcatggaaga cttcttcgtt gacttcaata gatgaatcat
     6301 ccaaaaaacg agcggttcct gaaagatgat cgatttcagc ttctgctaat tgtttttttc
     6361 ggctttctgg gactggatcc gtaaatgttc gtttgaattt ttgaagttct tcccagttgg
     6421 cagttgggat ctcgttaaaa ccttttccac tcaattgttt tacccgatta cgtgcctcta
     6481 ctgcacttaa caagactttt ttaggatcac atccacggtt aggacaagtc ccgccccata
     6541 gatcttcttc gaccactagt actgttttac ctgcttcttt caatccataa gcagcactta
     6601 agccgctcac acctgaaccg atgatgattg catcatatgt tttcatttcc ttcctcctct
     6661 cgacttaaaa aagcaaagat ttctttactt gtcagcgacc caatacttct ttgcttttct
     6721 actatcacaa tgcttggata caccgaaaga agcgaatata cttctttcat aggcgtatca
     6781 aagcaaactt gttgacgagc attttctggt atttcattta agaaatatcc attgacgact
     6841 aaatcttcta ctcgccactc tttcgtctgt ttcggttcat caaagaaatg ccgaacgtag
     6901 tcgtttttag gattcatcaa taactgctct ggtgtgtcac attggataat ttctccatcc
     6961 ttcataaatg caatacgatc acctagcttg attgcttctt ccatattgtg cgtaacgaaa
     7021 acgatggtcg tgcccaattc ttcgtgtaag gacaaaacca attcttgtaa tgagtttctt
     7081 gaaatcggat ctaatgcgct aaatggctcg tccatcaaaa tcacatctgg gcttgcagca
     7141 atagctcgga tgatcccgat ccgttgctgt tctcctccag acaactctct aggcatacga
     7201 tctcgataaa tatcaggaga taagccaact ttttgaagaa gttcatctac acggtctgct
     7261 cttttctgct tttcccaacc taacatttca gggatgactt caatattttg cttgactgtc
     7321 atggtcggga acaaagcgat ttgctgcagc acatatccca tattccaccg cattttctgc
     7381 agattatatt catttaacga ttttcctttg aagtagatgt ctcctgctga tggtttagat
     7441 aatccattga tcattttcaa agtagttgtt tttccactac cggaaggacc aaccaaaaca
     7501 aagatttctc cttttttgat tgccagattt aggtcatcga tgacatactt tccatcatac
     7561 tttttttgca catgtttgaa ctcgattaat ttagtcactg atcttcctcc tttactaatc
     7621 cttcattttt caggaagatt cgtgctactt ctgtcggctt tttcttttcg acattgactt
     7681 ggtaattcat atcaatcatt tgatcctctg ttatttttcc gcttaattta ttcagtgctt
     7741 taacgatttc aggatgttct ttagcaaaat cttttttcat cagcggtgcg ccttgataag
     7801 ctgggaataa ccctcgatca tcttctagag tcactagatc gtactccttg agctggctat
     7861 ctgtggaata ggcatccaca atattgacat ctccattatt gattgcttgg taacgcaaac
     7921 ttggctccat gctttgtaca cttgaaaaat tcaagccata tgcttcttgg attcctttat
     7981 atccatctga acgatcaata aattccagtg tgaatcccgc tttgatctga tcagagatag
     8041 ctgccaaatc ggaaatcttt ttaagttgat gttcgttcgc aaaagatctc ttgactgcca
     8101 aggcatacgt attttggtaa gccattggtt ttaataatgt catatcgaat tgcttattca
     8161 ataattcttc tgcttcgtca tatgtttttt cttttgtcaa atcagcactt ttcattgctt
     8221 caggtacctt caccaagctt tctaggacag tacctgtgaa ctcaggatag atatcgattt
     8281 gaccttgatc cagtgcattg aacaaaaaac tcgtcttgcc aaaattcggt tttaattcaa
     8341 cttctgtttt tgtgttgtct tcaatcaatt ctttatacat ttggatcagg atttcaggtt
     8401 ccgctcctaa ttttccagca atcgtgatgg tttcattttt aaacaaggca gactgatata
     8461 aagaaacgcc gccaaataaa cacaccactg ctgctaaagt aatgatggaa tatcgaggtt
     8521 tcttatgctg caaccagcga atcagtccgc tgaatataat tgcaagcaag gcagaactga
     8581 tcgcaccaat caatgtcaaa acaggtgtat ttcggtcaat acctaacaaa ataaatgtcc
     8641 ctaatccacc tgctccgatc aatgctgcca aagtagccgt accgatgatt aaaactaagg
     8701 cagttcggat acctgagata atgacaggta atgcgatggg aagctctact ttcagcaagc
     8761 gtctcattct ggacatacca aatgctaccg ctgcttcttc aatagacggg tcaatttcag
     8821 ctagaccaat atacgtgttt tggaaaatcg gaagcaaagc gtaaataaca agtgcaatca
     8881 atgctggaac agttccgatc cctacaaatg ggataagtaa acctaataag gcaagtgaag
     8941 gaatcgtttg gagcacaccc gtgatctgca ataagacttc tgccattttt ttatgattgg
     9001 ctgcccaaat cgctaaagga atagcaatca gtgctgcaat cagcaaagaa atgagagaaa
     9061 tggacagatg ttgaaatgca gcttccagca actcgccttt tctttcactt aatgtttgta
     9121 taaaattatt catgcgacct tcctttctgt tattctttaa gtataaacat ttctttcctt
     9181 tttcccaact aacttgtctt gccttaacct tacagcacga acaaaaaaaa gaaaaaaata
     9241 cctctaaata tgctgacaaa aaaagaatcc aagcaacaaa gtcggatcaa ctttttggtt
     9301 ctcgtttttt cactacgaat accataaaaa tctatacgaa attgtcactt ggaatcagct
     9361 atatcttttt tacacacaca acttttattt taataaaaag aaacagccaa taaagtagaa
     9421 atctcgtggg ggagaacacc tttattggcc tgttcaacga atattatact gtatcatgac
     9481 acttttttgc caaaaatgta aaaaatggtt gttttgacat cataaacgtc ttgttttctt
     9541 atttttactt atatcaccac tttattttct atctctttca ctccataaag aggaatgagt
     9601 tcttcttttg actgataata aacagctttc tcacggttct tcatcaaaaa aagaaagatg
     9661 tctttcatag caagtggtgc tttgccgtgt tcaaataaaa agataaattg atttgcttta
     9721 tttatctgga ccattgtcac aggcaccagt ttttgttctt gagccaaaaa aactccttga
     9781 tactctgttt ttttgggtga ttttgtaaga attgtcaata agtctgctgc tcgcattttt
     9841 ccactcctta tttgataaat aaaaagaaac agccaaaaat aatttttttt cattttcctc
     9901 ttgaagtaag agtataagtc agtataataa agaagttgct gaaaattttc aaaagaaaag
     9961 aggctagaaa tgaaaaaatt aaatttattt acagaattgt gcggaatcat tttaggcgca
    10021 ggaatctacg gattagctgt gacaggaatc aatattccat ctaagctggc agatggtggg
    10081 gttactggta ttgctttgct tttgcataat ctttttggat tcgctccttc tgtcacttca
    10141 ctgcttttta atttaccttt attgcttatc tcattgtttc tttttggaaa acacgctttt
    10201 ctccggacga tcgtcggaac atttgcgcta gttttctttt tacatttatg ggagagcctt
    10261 catatacatt ttgctgtaga tagtctactg atcaatagtt tgatgacagg tattctttct
    10321 ggcattggtt gcggtctcgt ctttcgattc ggcggaagca caggcggaac agatatcatt
    10381 tatcaagcca ttgaaaaata ttttcatatt aagattggca aaagtctttt cttgattact
    10441 tttggtattt tagttgtctc cttgctttat ttggatctca cacattttct gtatacatta
    10501 cttagctgtt ctattctatc ttatacattg aataaagtga agtatctgga aattggatct
    10561 gttttgcccc aattggaagc aaaacagact acagaaacat ttgaaccact tgatcctctt
    10621 gaacagttag agcactgatt cttatttttc actactttat ttaatttaca gaaatatcat
    10681 tatgtaaact aaaatgatat tattcagtaa aatcttcttt ataaaaaaat aaactatttt
    10741 tgcaaacgat ctgcgaaaat agtttgtttt tttattttgc cattattttc ttacttattg
    10801 ggagaaaaaa ttcgcttaaa ctcaaaaaaa tttgaggata cgatataaac tttcggatag
    10861 agtataaaat aaggaaacgc cgcagcgttt cctttccaac tgtagccgaa tataaatttg
    10921 tatatcactt atttaaaata gctattttct cccaaagagt ttccttgatc atcgatcaat
    10981 ccttgtaatg agcgttctaa gataccatgg ctttttttcg attttttttc ttctgactgc
    11041 tttgtttcct ctaacgtttt tgttcgattg aatgttcgta cagacggctc accatttctt
    11101 ttttcttgat acggcgtcgg ttctgtatcg aacaacagat aagagtcatc cgtttttttc
    11161 atcgattcga ttaaatgatc ctcagaaatt ttgctttctc tagggtctgg gataatcgat
    11221 gcgggtacat atttaggaac aaaataagaa cgctcccgca ccttcgtgtc aacagatgcg
    11281 tttcgtgtag tatgcttgga ctctgtcctt gtttcacttt gtctgacaga acgagaggaa
    11341 tcaccaaaaa gtttttttcg tcctgtcgat gtgatttctg attggtaatg gccggtataa
    11401 tccggtaatt ttcctttatg cttttccaaa ttttccttac gcggagctga cttcaatcca
    11461 tttgttgcac gacgcttgcg acggattttc tcggtgttcg tgttcgtgaa atgaaattct
    11521 ttcatctgtt caaacgggga ctgattctgt tcagtcaaaa gatcttcttg tccgtcaaat
    11581 aatactcgct tcttgtcgtt ggttaatttt acgcctaact catcatcgta cgcaggaaaa
    11641 cggaaatgtt ttcgtctgat ttctttcatt caaaccatcc ttctcaaaaa tggaactttt
    11701 ctcaataata gcacagattc attgttttca gtagcaatgc gctgattatt ttaagaaaat
    11761 agcgatgaat ttcataaata tatatatagt aataagactt aattcgttgt ctctctgata
    11821 actagttcag gaaaaaaacg acgataacct tgactcgccc ctttttcttc tatttttttt
    11881 aacaacattt ctccacatac ttcacccata cgtataatat cttgcttgat cgttgtcaat
    11941 ttaggtgaac tgatttggtc taaaaatacc ccatcaaatc caatcacacc aaattcttcg
    12001 ggcaagtgtc ctccagcatt tataatccct cttactgctc ctagtgctag ccgatctgaa
    12061 ctacatacaa aacaagtttt atctgtaaaa tctgcccagt tttctgtcat atatctttct
    12121 acttctgtcg aatgatttgg aaaccgcaag attttactag gaagatcaac ttccttcatc
    12181 acagataaat aaccagtttc ccttgaaatt tcaaaaggct cgtccacttc gataccgata
    12241 taaataatcg tttgataatc tctttctaag gcatattgcg ttgcttttgc tgtaccatat
    12301 tcattatcgc tgtctacata atcatatcct tcagaatttt ccccaaacaa gacaactggt
    12361 ttttccaaac ggtcgatcca atcgaagtct ttttttctga cacctgtgat gatgtatcca
    12421 tcacaagaac cgacgtcgaa ggcatcattt gtaactaatt ggagagaata atgcgcttta
    12481 ccgatccgtt tagcgattcc catcagcaaa ttcatgtaat agggctcagt tgtgtcgatt
    12541 tcttccagta taaataattt gatgatctgc gaccgattcg tgacaagtgc ttttgcagca
    12601 atatttggac ggtaatccag ttcagccatt gctgagaaaa ctaactcttt caattcgtca
    12661 gtcacctgtt ccggatgatt gatgactcga gagaccgtca tttttgaaac attggcacgt
    12721 tttgcaacat ctgctaaagt gggcatgctc tcttcctttc taacatgttg tcattcttac
    12781 tatcaattat accaaatttt cctaacagag tttattatag cccaaaataa aaaacggaaa
    12841 atcctctatc gtcatgagtg attttccgtt tcaattattt atactttttt atcaaatttt
    12901 ttgctaaaaa agtggaagct tcttccatta gtggtatttg taccatatgt cgctgtgttt
    12961 ttgaggaacg aaaaacaatt tcttttccgt aagacttatg ccgatttttt tctacaaatc
    13021 gttccgtttg tatataaggg attttttcgt cagcttgtcc atgccaaaag aacagaggac
    13081 gtccagctaa cttttccggc tgcaatgaca aatcatagct cttaacccat gaaatcaaat
    13141 caaaatagtc ttttggtacg acataattat attccgatgc gcgccttacg atttcttttc
    13201 catattccaa aggtgcaggg gaacccatca aacacacgcc cgctactata tgaggatgtt
    13261 tagccaacaa ggcgcatgtt gtcattcccc ccatcgaaac cccgccaact gcaagctgat
    13321 catgtagaag acctcttttt tctaaatgct tgataagtgt gtcaaattca aacagatttc
    13381 cgtagatact atcccaaaat gtataggatg gaatagaaga aaccggctgt ttgcgctccc
    13441 catgattcat cgcatctggc aggatcacac gaatgccctg ctgcgcaatt tttcttcctt
    13501 gcgtcaaaac taactcctta cttgtctgcc atccgtgata atagatgaca acgggaatac
    13561 gttcctctct taattctttc agaacaactt ctaacactgg aatatgatgg acagaacgtt
    13621 tcaatataat tggattcaat tgttactcac ctattttcat taaatttcct gatcgccata
    13681 gcaaccatgc tccaacagtt gtctggaaca ggttcagtgt accaaataat ataaatgcag
    13741 gactgaatgg ctcgggaaat aagcacagag aacaaagtcc caccactcct aatgctagcg
    13801 aaaggagtgg ataaatagaa aaattcaaaa aactggcaac gctaccgaaa atattaccaa
    13861 taaacagtat caaaaagaaa aaaacgctta aaattaaacc atctgtcagc gacatctgaa
    13921 aaacaatgtt ctctacctca attggctgtt gaatcgaata gacacctaag tatatactga
    13981 gaaggagact tagcacgtgg ctggcacaaa acacacgatt gaccgttttc attttaatca
    14041 cctaacctat ctttataatt ctattataat cattttatca tttttttgta tgtataaagt
    14101 ttcaattttt cttcacttac gatttttttt gatattgttg ttatataaat gaaaggagtt
    14161 ttacaaatga ttgatccaaa aatgttgggg atgatcttcc tcattaattt tgcttatatc
    14221 actctgaaca cgttacgttt catgttgaca atgaaaggct atcgactgat tgctccactt
    14281 gtcagtatgg tcgagatcac gatttatatc gtcggcttat cccttgtttt agatcgttta
    14341 gataatccac tgaatttatt tgtctatgcg ttaggttacg cagtaggtat cagtgtcgga
    14401 attttgattg aagacaaatt ggcattagga tacatcatgg tcacaacgat tttgccagca
    14461 aatagcgcag aagataaaag tttgccgggt atactgagag aacacggtta tggtgtgaca
    14521 cagacttctg caatggggct ggaaggtgag cggctagttc tcgaaatact ttctcctaga
    14581 aaaagcgaac gtgaactgta tcgcctgatc aaagaaatcg aagagcgtgc ttttatcatt
    14641 tcttatgagc caaaatatat ttcaggtggt ttctggacta aaaaagtgag aaaacgacaa
    14701 ggaaaataac tcacaaactt aaaaactgtc taatatctaa attaaatttt aaatgttaga
    14761 cagtttttat ttattatttt gattaaaaaa catcgacata tactcatcaa tttgttatta
    14821 tactttatat acttatcaat ttaatttgga gatattatgg aaattcaacg tagaaccact
    14881 aattttttac atttaggctc tttttttgca actttgacga tcttattttt tctatgttat
    14941 tcatacctta agacctcaca tgcgccttct agtgcattag gctggttgct tttggatcat
    15001 tctgatatca cagaagccga agaaaatccg ttttttttga ttttgtcttc tctttgcggc
    15061 ttactgtttt ctgtttattt cggtgcctat ttttttcatc gacatcctgg tacgttaaac
    15121 gaagcttcaa gcgtattgat tgcatttaaa acgttttctt ttttagcaat tcttttttat
    15181 tcgtttaatc acaatacgct tttcttcttt atcatgaatg gtttagtcgt gattttatcc
    15241 atttttactt attttatttt ttcactcatt tttagccaat tgaaatgtcc gctcttcttt
    15301 cgattagttc ctgtcacctg ttttatttac agcttgtttt ccttttttgt ccttgcttta
    15361 atgccactga ccaacccttc gacgatccaa gtcgcaggaa atctgttgga tatgctcttc
    15421 atcgtcagtc taggtgtatt tatgtggcaa agaaaaaaca aacaaaataa aaagcatttt
    15481 gaagcctgac tattacgact tcataaatgc ttttttagtt ttaaacactt caatctaaaa
    15541 gaataaccca agattggata aattattaat gactcgccat tcgtttctta gtgattctgg
    15601 attatcaaat ggacttccta atctaatcag ctagttcttc ccataaaatg ccatacttga
    15661 ctgaatcata atattgatta tttaaaaatc taacttttct tatcactact tcctttgtca
    15721 ttccacattt ctcaccattt ttttgcattc ctttgtttcc agaccatgta gtgaatctaa
    15781 taggtggtag ataggcaaaa tactcaaata attcttttaa ccataaagga agagaaaggc
    15841 tcctcctgca agggtcagta taatttttgc ttactgctct cttaggtttt actcactaaa
    15901 actgttccat attctttgat ataagaaaat gcatgcggta taaatttctt gctcagctca
    15961 gaaaagattt gtcgtttaag aaaggccatt tcctccattg tcaatgaagg atccaatgtt
    16021 ggtaattcaa tctcaaaatt gtttttttcg acaataggta attctaatgt gaatgattct
    16081 tcttccttta tagtattcgt cacaagtaga gactgatgga aaatactagg ccggcgattt
    16141 ttatatttat tcttacgtat cctgtcaacg ataacttcta tttgatcaaa aaagtacgat
    16201 tcatttacgt ctccaataag ttcggctaat tctttgaatg ccttcgttac aggaagctga
    16261 ttcttctgta caaaaaagta attagccaaa gtaagcggga agtgttctat agaggaaagt
    16321 gtgataaaac ggtacttctc atttcctgca gttgtcctca gcaattctgt ctctcggctg
    16381 tttcttactc cataaaaata cgcttctttc cgttcatctt cgaaacaata cgcccaaata
    16441 acttctccca tcgctaattt ttgttcatca acagagagtc tcttcaattg ttcagctatg
    16501 gtttcagcag ccgaagtggc ttgttgcaag taatctttag gatcaaatat tggaaagttc
    16561 aaatgatatc ttcgttcttc cctcttgatt aatcctgcat cgatcaataa atcaagaaaa
    16621 tgggaaaatt tattttgcga aaattctttt ttcaattctc ttagaatcgt ttcttgttct
    16681 cgatgttcat atagataatc ggtcaatgaa gaaaaaagcg gatcatcggt cagtttttga
    16741 taaaagtttt ccttattttt tgaataatag ttcatatatg ttctcttttc tatccgtttt
    16801 attttactta aaaggctttt acgtaaaaag gaggaagaac aagagtcata attgactgtt
    16861 attctcctcc atttcttcgg cctttagtat gttctatgtt tctttttata tcaatcgctt
    16921 atccattcat tttgaatgct tcatactacc atttgattag ctaaatacag ccgtcaattg
    16981 aggtacgact tgttttttac gtgaaacgac acctttaagc aaagcacggt tgttggtcaa
    17041 agttgtttgg aaagcttctt ctactttttc ttttccttta ccagcaacaa gtaattctga
    17101 atcactgtct aagatgtttg tgacaactaa tacgaacaga tcgtagccat ttgctttcat
    17161 ttcatcttcc attgctgctt ctagctctgc ttgtcgatcc atcacttcat taaggtccac
    17221 tgtattgact tgagcgatac gaacgttgga actgcccatt gggaaacttt ttgcatccaa
    17281 atcaagaaga accgcagctg atttatcact tagatttgtt cctgctttca acatttcaag
    17341 tccataagtg tttagatcga cttcagcgat tgctgcaagt tcttttgcag ctgcttcatc
    17401 ttcaggcgta catgttggtg atttgaacaa caatgtatct gaaatgatag ctgagagcat
    17461 gattcctgcg atttctttag gaattgttac ttggttttct ttatatagtt ttaaaataat
    17521 cgtacttgta catccaactg gttctgcacg atagtacaat ggattagctg tttcaaagtt
    17581 tgcaatacga tggtggtcta ctacagctaa aatatttact tcgctgatat ctgaaatact
    17641 ttgttggaat tcattatgat ccacaagcat gacatctgca ttttctgctt tagctgactc
    17701 tactactcgt ggtgcagata gctgaaagtg gtctaatgcg tattgtgttt cttcattagg
    17761 tgtacctaga gcaactgctt ctgtttcttt acctaattca ttttgcaagt gtgaaaacgc
    17821 aatggctgcc ccgattgcat ctgtatctgg attttggtga ccaaaaacta aaatttttga
    17881 catgtcattc gctcctttgt gatttctcct atttaataat agcaaaaaaa cggaaagaag
    17941 caatacttat cttctttccg atgcgaccta tcgcgttaaa tattttgtat actcttctgt
    18001 atgaagcaat cgtttagcat tttcgacacg ttcttttgta ggtggttcga tcccttctaa
    18061 tggatatttc aaaccaagtg tttcccactt gtattttccc atcgtatgat aaggaagaat
    18121 ctctactctg tctacatttg acaaggtttg aataaagttg tctagtcgga tcaaatattc
    18181 atcataatca cttcgctcag gaactagtac atggcgaatc caaaccggtt tgttgatttt
    18241 tgacaaatat tgagccattt ctaaaatatt ttcattgtcc caatgcgtta gttttttatg
    18301 ctcttcatta tcgatgtgtt tgatgtcaaa taacagtaaa tctgtatact tcatcaattc
    18361 ttgaaaacgt gaaaagaaag gttcttcata cgtaaaaggt tttccgcatg tatccaatgt
    18421 agtatgcatc ttccgctctt ttgctttttt aaatagttcg atcaaaaaat cgatctgcaa
    18481 tagaggttct ccaccactaa cagtaatacc acctttatct ccccagtaag gtctgaagcg
    18541 ttctgcttta tctaaaagtt catctgctgt gtattctttc cctccgccaa tattccaagt
    18601 atctggattg tgacaaaatt ggcaacgcat gcggcatcct tgcataaaca cgacaaagcg
    18661 cagtccaggt ccgtctactg aaccgaaagt ttcgatagaa tgaacatagc cgattgtttt
    18721 ttcttccatt taagttcaca tcttttcttt gatttcattt taagtacaag ttagctgtcg
    18781 aagcgaagct ttctgaacaa aatttttcgc aattgccgct tcgttatgtg taaaatttac
    18841 agggacggaa catacaagtc ctgcccctgt aaatcgtttc tttcaaataa gcatactgat
    18901 tattcgattt tgatgcgatg gctattcaac gtcctttcga cgctaagtcg aaaaactttt
    18961 ttcacgaact ttttacattc tgtcgtgtga agttctcatc aagacatcta attgttgttc
    19021 tcttgtcaag tcacggaatt taactgcata accagatacc cggatcgtca agttcggata
    19081 tttcattgga ttttccattg catcacgcaa taaatcatta ctgaatacat tgacattcaa
    19141 atgataagct ccttttgaga agtatccatc taagacatta cgcaagtttt cgattcttgt
    19201 atcttgttct tttccaagac ctgaaggatt gattgtttgg gtatttgaaa ttccatccaa
    19261 tgcacagccg taattcattt tagctgttga gttcaggcta gctaataacc cactttgttc
    19321 cgcattgtaa cttggatttg ctcctggcgc aagtggtttt ccagcttcac ggccatcagg
    19381 agtatttcct gtatttttac cgtaaacaac atttgaagta atcgtcaata atgaagttgt
    19441 tggttttgag ttgcggtaag ttttatgacg tttgatttgt cccatgaagt attccaagat
    19501 ccatgaaact aattcatctg cacggtcatc atcatttccg tatttaggga agtcgccatc
    19561 cacttcaaaa tcaactgcta ttcctttttc attacggatt gcttttactt ttgcatattt
    19621 gatcgctgac aagctgtctg ccgcatgaga gatcccagca atacctgtag caaatgtgcg
    19681 ttgcaagtca gaatccatca aagccagctg agctgcttca taagaatatt tatcatgcat
    19741 ataatgaatg atgttcaacg tattgacata tagttctgct aaccaatcca tcatattcat
    19801 gaagttatgt ttcacttctt caaagtctag tatttctgat gtgattggac gatattctgg
    19861 tccaacttgg gcgccagtca cttcatcgac tccgccattg atggcatata atagtgtttt
    19921 agccaagtta gcacgagcgc caaagaattg catgtctttt ccgacaactg ttcctgatac
    19981 acagcaagca atcgcacaat catcagaacc ccattgttca cgaagctgat tatcattttc
    20041 gaattgaatc gaagaacttt cgatagcgat tctgctagca tatgttctga atccttctgg
    20101 aaggtgttca gaatacaaaa cagtcaagtt tggttctggt gaaggtccca tatttgttaa
    20161 tgtatgaagc agacggaaat cattctttgt aactaatgaa cgaccatcta atcccatacc
    20221 tgcaatggat aaagtagccc agatagggaa tcctgagaat aattggttat attcaggtgt
    20281 acgcgcgaat ttgaccatac gtaatttcat tactaagtgg tcgatcaatt cttgtgcttc
    20341 tttttctgtg attactccat tatccaaatc acgttggata tagatatcaa ggaatgctga
    20401 gatacgtccg attgacatcg cagcaccatt ttgtgatttg attgctgcta aatatccgaa
    20461 gtatagccat tggacagctt cttttgcatt tgcagctggt ttagaaatat catagccata
    20521 tttcgcagcc atttctttca tttgcgctaa tgcacgatat tgttcagtga tttcttcacg
    20581 taaacgaatc acttcttcac tcattgtatg ataaccagtc atatcatgat cttttttctt
    20641 ttgttccatc aaatagtcga ttccatacaa tgccacacga cgatagtcac cgatgatacg
    20701 tccgcgaccg taagcgtctg gaagccctgt aatgattttg tttttacgag cagcacgcat
    20761 ttcagcagta taagcgtcaa atacaccttg attatgtgtt ttgcgccagt cagtgaaaat
    20821 atgtgtcaat tcatcgtttg gtgtatagcc attgcttttt agcgcattgt tagccatatt
    20881 gattccgccg aacggcatga atgcttgttt caaaggtttg tctgtctgta gaccgacgat
    20941 tttttccaaa tctttatcca aatagcctgc atcgtgtgaa gtaatagttg atacgatttc
    21001 tgtgtccata tcatagacac cgttacgctc gaattggata tcatttaact tttgcaattc
    21061 atcccataat ttttctgttg cttctgttgg gccttccaaa aagctgtcat caccgcgata
    21121 ttcagtgtag ttattttgaa taaagtctct agtgtctacg ccttctttcc atttggtacc
    21181 tttaaatcca ttccattgct ccattgtatg gacctcctaa atttctgttt tatgtaacag
    21241 tttttacgtg attagtataa cacagcaccc tatctttgca agggttttct tgttttttat
    21301 ttaacaattt ttatgtttta tttacatata tttaaatcaa cgttgacata ccaacattta
    21361 agcattgtga acactttcat ctttttttgc aaacgtataa ggatttatta aaaatgaatg
    21421 aaaaagagac gccacctgta ttaatacaga tggcgtctct tcattaaaat actacaacag
    21481 ttacgactcg atgaaaatct caggagcatc gataacttcg atgacttctc cacctttttt
    21541 ctcatccatc gcaaatgatc cattcgatgt tcgatcacct atagggaaat cagttgggtc
    21601 aatcgttaac tgctgccctt tttgattcat caaggttatt tcttttgatc ttccttccga
    21661 catatagata atacggtgcg gatttttttt cagctcacgc atgaccgtca ctccccgctt
    21721 cgcacgtgaa gtttggctga tttcttgagc aagcatgcgt ttaacagctc ctcgctgagt
    21781 aacgattacg atcggcgtat caccttctgc taacacaagc agcccgttga taatcctatc
    21841 tccatctttc aaattcatag acttcactcc agctgccttt gctccaacaa cgggaacatc
    21901 tgttaaagga tagcgcaaac ccattccttg atgcgttact aagaaaacat ctaagcctgg
    21961 ctgatcttct ttcagataca cagcaatcag ttcatcttct tccgccttta gcttcataca
    22021 gctgagcgga cggctcttat aggtgcgcca tggttcgaac tctgtcattc gtgtttgctt
    22081 gatcaatcca ttcttgctga tgaatacaaa tgttttctct gcttgaattt tttgatatgg
    22141 gaaaacagct aaaatcgatt cgtctacaga cagattggag attgtttgag aaatgtgctc
    22201 accagcatct ttccatttca aatcgggtag ttcatggaca gggcggtaga tcacatttgc
    22261 tttatttgtg atcagaagaa catggtccaa tgtactcaat tcacctgagt atagcaagta
    22321 gtcgccttct cgcatcccga tttcttctgg tttggaagca ctataagaac gaaggcttgt
    22381 tcgcttcaca tagccttctc gcgtcacact gacaattacg tcttcttgtg ccactaagac
    22441 ttgcgtatca attttgattt cttcgatttc gtcttcgatt gtcgttagac gagcggaaga
    22501 ataatttttt ttcacttctc gcaattcttt tttcataaca gagaaaagct ctttgtcatt
    22561 tgaaaggatt ttattcaact ctgtgatttg cgcaatcaag ctttcggatt ccttttgaag
    22621 ctctgtgata tccgtgttcg tcaaacggta taattgcaat gtgacaattg cttctgcttg
    22681 ttcttctgta aattgaaaga cgtcgactaa attctttttg gcgtcttttt tgtctttact
    22741 ttcacgaatc gttgcgatta cttcatccag aatcgataaa gctttcatca atccttctac
    22801 gatatgctgt cttttttgag ctttggctaa atcgaattga ctacgttttg ttatgacttg
    22861 ctttcgatgc tcgatataac ttcttaaaat gtctttcagt ccaacttgat gcggagtcat
    22921 atggtcgata gcgaccatat tgaaattgta attgatctgt agctcagtgt ttttgaacaa
    22981 ataattcaaa attccttgag cattggcgtc ttttttcaat tcgacgacaa tttgcagacc
    23041 tgttctatca ctttcatctc gtacttcagc tattccatcg attttcttat tcaaacggat
    23101 ctcatccatt tttttcacca aggtcgcttt atttacttca tatgggattt ctgtgatcac
    23161 gatttgctgt ttattaccct tcattgcctc tatctttgtt ttcgaacgaa gaataacttt
    23221 tcctcgtcct gtttcataag cttttttgat ttcatctttt ccttgcaaga tccctcctgt
    23281 tggaaagtca ggtccaggaa tatattccat caatttttca aggctcgctt gtggatgatc
    23341 gatcatatag attgtgccat cgatcacttc agctaagtta tgagtcggga tttctgttgc
    23401 atatccagca gatatacctg tcgatccatt gacgagaagg tttgggtatc gagctggaag
    23461 gactgttggt tctttttctg tatcatcaaa attccacacg agatcgactg tttctttctc
    23521 gatatctgct agcatctctc cacttaactt ggataatctg gcttcagtat aacgcatcgc
    23581 agcaggtgga tcaccgtcca tactcccgtt attcccgtgc atttcgatca gtacttcccg
    23641 caacttccag tcttggctca tgcggaccat cgcttcataa atactgatgt caccatgagg
    23701 atgataattc cccatgatat ttccgacaga ttttgctgat ttacggaatc ctttgtcata
    23761 cgtattgcca tctttgttca tggcaaataa tatccggcgt tgcactggct tcaatccatc
    23821 acggatatca ggcagtgcac gttcttggat aatatatttg gaataacgtc cgaagcggtc
    23881 acccatcact tcttctaaag ttaattcttg tacttcttgt cgattttcca tcaggtgacc
    23941 tcctattcta cttcaaataa ctgattgttt tcatttttat ctgctcgttc ttcatctaat
    24001 aaatcattag aaactgaagg agagatttca gtatcctctt ttttatctaa gatactgcca
    24061 tcttcttcga gcgtaaattg cacgtgattt tcgatccatt ttcttcgagg ttctactttg
    24121 tcacccatca gtgtggttac tcgacgttca gcttgcgcag catcatcgat acggacgcgg
    24181 atcaacgtac gggaagtcgg atccatcgtt gtttcccaca attgttccgc attcatctct
    24241 ccaagtcctt tatatcgctg cagcatatat cctttgccga cttttttaat cattgctgcc
    24301 aattcgtcat ctgtccacgc atattcaatg acttgcttct ttccttgtcc tttggatact
    24361 ttatataaag gcggtaacgc gatatatact ttcccagctt caatcagcgg tttcatataa
    24421 cgataaaaga aagtaagcag taatacttga atatgggcgc cgtctgtatc cgcatcggtc
    24481 atgatgatta ctttgtcgta attacagtct tcgatagaaa actcaggacc gactcctgca
    24541 ccaatcgtat agatcatcgt attgatttct tcatttttca agatatcttg cattttagct
    24601 ttttcggtat tgatgacttt tcctcgtaaa ggtagaattg cttggaactt tctgtctctt
    24661 ccttgtttag cagatccgcc agcagaatcc ccttcgacta aatacaattc atttttctta
    24721 gggtttcggg attgtgcggg tgtcaatttt cctgaaagaa gagattcgcc ttttttacgc
    24781 ttcttcccat ttcggctttc ttctctggct ttacgtgctg cttctctcgc ttctctggct
    24841 ttgattgctt tacggaccaa catctggctc atttcgctat tttcctgcaa ataaaagccc
    24901 atttgttcac tgatgacgtt atctactacg gtacgagcaa ctggcgtacc aagtttttct
    24961 tttgtttgcc cttcaaattg cagaagattt tcaggtacac ggatagaaag tacagcagct
    25021 aacccttctc tgaaatcact accttccaga ttcttgtccc gttctttcag caaaccaact
    25081 tttctcgcat attcattata agatttcgtc atcgccgctt tcataccagc ttcatgggtt
    25141 cccccatctt ttgtccgaac gttattgaca aaagataaaa cattttctga ataaccgtca
    25201 ttgtattgat aagcgacctc tacttcgata ccttcttttt ctcctgaaaa ataaacaact
    25261 ggtgtcaatg tatctttttc ttcattcaga taatcaacaa attctttgat tccttcttcg
    25321 taatgaaaaa tttccttgac tggttcttct ccacgaagat cagaaagaga gattttaacg
    25381 ccttttagaa gaaaggcaga ttctcttaac cgttcggcta aaatttcata tgaaaatttc
    25441 gttgtactga atattgtatc atctggtaaa aaatggacag tcgtcccgtt tgcttttttt
    25501 gtttttccta tctttttcaa agtaccgtca ggtttaccgc cgtttttaaa tttctgctga
    25561 tactctacgc catctctaac gatcgttaca attagccatt tcgataaggc atttaccaca
    25621 ctggctccta caccgtgcag tccaccagaa gttttgtacc ctccttgacc aaactttccg
    25681 ccagcatgca gcacagtaaa aatcacttca actgttggta ttccggaagc atgcattcct
    25741 acaggcatcc cacgtccgct atctgcaaca gttatactat tgtcttcatg gatggtcaca
    25801 tcaatctcac tgccataacc tgataatgct tcgtcaactg cattatcgac gatttcatag
    25861 actaaatgat gcaagcctcg gctgtcagtg gatccaatgt acatccctgg tctttttcta
    25921 actgcctcta atccttccaa tacttggatg gacgagtcat tgtattcgtt gtttactttt
    25981 tttgccaagg caaacgctcc ttcaataata ctttgcggca aaaccgcacc acgattatca
    26041 tactagaaaa ggtcgtgaaa aaaaagaggg tagacgagaa atcaatttta attatctcct
    26101 aaccgctttt tcgacattcc cctctatcga tcatctcttc tttgtggtca tttttatttt
    26161 tggttttctt tcaacttacc aagttcaatc ttaatacaac gatccattac gatatctgta
    26221 cgtcctgctt ttcttagcat ctcagctgct tctttgtttt caatccctaa ttgtgcccag
    26281 aacactttag catcagtttt caaaaaatca cctgctattt caggtaaaaa ttcactccgt
    26341 ctaaatacat ctacgatatc gattggatca tcgatttctg tcaaattcgc atagactttc
    26401 tcgcctagaa tttcttcacc agccaataat ggatttactg gtatgatttt atatccattg
    26461 tcttgcaata cctgtgcaac catgtaactt gttcgttctg gtttattgct caagcctacg
    26521 acggcaatat tttttgcttc ttccaaatag ttgaaaatcg tttcttgtgt tggatttttt
    26581 acagacattt ctgccacccc ttgcttttct ttttattcca tctattatac ttgtatcttt
    26641 cattttttca attgttcctg ttacctattc atgctaaaat aaaggatagt tttcaacttg
    26701 aaagagggta aaaaatgaaa ttgatcttat tacttatttt agcatatctt ttaggttcta
    26761 ttccttccgg tgtctggatt ggcaaattgt ttttcaaaaa agatatccga caacacggga
    26821 gcggtaatac tggaacgacc aatacatttc gtgtattagg caaaacagcc gggattgttg
    26881 tcctgcttat ggatatttta aaaggtacat tggctacttg tttgccgatg atcttccacc
    26941 tttctgggat taaccctctt tggtttgggg tatgcgccat tcttggccat acatttccga
    27001 tttttgctgg gttcaaagga ggaaaagctg ttgcgacaag tgcaggaatg cttttaggat
    27061 ttaatcctgt attttttgtt tattcttgta tcatctttat cgttagttta ttttgtacaa
    27121 gtatggtgag tttgagcagt atgatcagtg cagtattgat cactttatct acgatcgtcc
    27181 ttccttatgt agctcctgtg attttggcta agcccaattg gttactgacg atcattgcct
    27241 ttttagtttc ttcctttatc ttttatcggc ataaagacaa tatcaagcgt atcagaaacc
    27301 atactgaaag tcgaatcccg tttggtttga atagcagcaa gaaaaaatcc tgatactttt
    27361 tcattccaaa gagataaaac gggagtgtga caaatcgatg tcacactccc ttattactta
    27421 caggatagct tttttacaca ccttggtaaa cggtgttccc tgctaacttc tcggtcacaa
    27481 cctcttactt cactgtgatg gaatattttg tcttgaagat ttcatgggca cctagttgat
    27541 tgatccctac tttttccatc aagtttccac tactgttcac cgtgtcagcg attccgcacc
    27601 acggttcgat acaaacgaaa ggcgcttctt ttggataagg agaccagatc cctacataag
    27661 gcatatcttt atagcttaaa gttacgctat gggaagattt ttcacttcga atggcgtacg
    27721 catttagacc ccttgtttca aaaaccaagg catcttgctc aaaaagttca cgattcaaag
    27781 ccagattcgt atttgtctga cctaacgtct tttgatccat atcgatgaat gggcctttca
    27841 atggtaggcg taatcttgat ttcaatggag aaaatgccag atagaaatct tcaaatgaca
    27901 atccttcttc aagaggtaca ttgaaagcag gatgtccacc gatagaaaag aacatttctt
    27961 tttcaccggt atttgccact tgataatgaa ccgtgatgcc gtctcctcct aattcatagc
    28021 tgatcactaa ttcaaaatca aatggatact tttctaatgt ctccggcgta ctccttaaga
    28081 tgaaactagc catttcttgt ccatgttcaa tgacttcaaa atccatatcc cgagcaaatc
    28141 cgtgttgccc catttgatat gttttccctt gataaacata ctgatcatct tttaaacgtc
    28201 caacaaaagg gaataaaacc ggtgcatgtc tgccccaata cgctggatca ccttgccaga
    28261 tatactctaa accatgttct tttgatttca gactgatcaa ttccgcaccg tgttcagcga
    28321 tttcggcgat cagctggtca ttttgaataa taacagtcat tgccattcct ccaacttcga
    28381 cttacttttt aaaatgggaa ggctggaaca aacatttcta tctgccccag tccccttact
    28441 tctaataact gtgttttgct aactcgtctt taaaacggga attcaatact tttaaataag
    28501 ttcccttcat gcctaacgaa cgagattcaa tgattccagc tgattccaat tttcgtaaag
    28561 cattgacgat cacagaacga gtgatgccga tactatcggc aatattagaa gcagtcagac
    28621 gaccttcatc tccatccaat gcttcaaaga tagcttgtac agccttcaat tcgctataag
    28681 ataatgtgtt gattgccatt tggacagccg ttgcactccg tacatctgct tcgatgcttc
    28741 gagacttctg ataaaggatc tgcataccga caaccgtagc tccatattct gctaagacta
    28801 gatcgtcatc tgcaaacgat tgttccatac gagataagat aatcgtaccc aaacgttcgc
    28861 cagctccaaa gatcggaacg acagtcgtca gaccaaatgg atatttctct cttgactcta
    28921 ccggaaatgc agtaatatca ctagtaattg ggatattagc ttcagttttc atcaactgtg
    28981 ccactgtatc agtataagat tcaggaaatt gtttctcaac aaacattgtt ttgattcgtt
    29041 cattgttcac atcgtgacgt tcattataac ctagtaatac tccgtcactt cctatgatat
    29101 aggtgttgct gtcaagaata ccacctagtg tgacagccat tttatcgtaa ggcaaatctg
    29161 cttgcatgtc aaaagtattc ttttgctgca aaagtgtgtt tatcttgcgg gttttcgtta
    29221 gcaagtctgt cattgtcgtc ctccgatttt ttataaaata tagcgactta aatcttcatt
    29281 tgccgcaatt gagccaagtt tgtcatccac atatgcttct gtgatcgtta tttctcccat
    29341 ttgcatatct ggtgcttcaa ataatagatc ttctagtagt ttttccaaaa tggtatgcag
    29401 tctgcgtgcg ccgatattat ctgtgtcacg gttgacatcg aaagcgattt gagcgatccg
    29461 ttcaattgct tcttttgtaa acgtaactga cacattttct gtaccgatca acgcgacgta
    29521 ttgttttact aaagcattat ttggttcggt cagaatcttc acaaaatctt cagctgtcaa
    29581 atcatctaat tctacccgta tcgggaagcg tccttgaagt tctggaatta gatcacttgg
    29641 tttagacaaa tggaaagctc ctgaagcaat gaataggacg tgatctgttt ggatgatccc
    29701 gtattttgtg tttacttgtg aaccttcgac aattggcaat atgtctcttt ggacgccttc
    29761 tctggatact tctccagatt gctgtgattt agaagtgatc ttatcgattt catcgataaa
    29821 aataattcca ctttcttccg ctaatttgat tgcctcacta tggatatcag catccttgac
    29881 taattttgct gattcttcct tgatcaataa ctctaaagct tctttgactg ttaccgtccg
    29941 ttccactttt ttcttcggtg tcaaagcacc tagagtttca tttaggtcga tccccatttg
    30001 ctccaatcca ttgttcatca ttggtgcagg tttcttttgg tcttcaactt caatggttac
    30061 ttcacgacta tccagtaaac ccttttgtag ttgttccaag actgtacggc gattgattcg
    30121 aatatcttct gtcacttctt cttgcggttc agcggtattt tgctgactag cattaaaaag
    30181 attcatcatt tgttcaaatt gattagtgga ttgtttctgt tcttttttga taccaggtac
    30241 caagattttt accaaacgtt tttctgcatt ttttttagca cttgtgtata cacggctgta
    30301 ctgctctttt tctacgattt ggatcgcatt ttctactaaa tcccgaacca ttgattctac
    30361 atctcttccg acataaccga cttcagtaaa ttttgttgct tcgactttga caaatggtgc
    30421 attgacgatt tttgccaaac gtcgtgcgat ttctgtttta ccgacccctg taggtccgat
    30481 catcagcata ttttttggtg taatatcttg ttgcattttt tcatctaact gcaaacggcg
    30541 atagcggtta cgcaaagcaa cggcaacaga tttttttgct gcgtgctgtc ctacgatata
    30601 ttcatctaat tcacttacga tttgtcttgg tgtttgtttt aattcataca tatctactca
    30661 cctcttacag ttcttctacg ataatattat gattagtaaa gatacagata tctgcggcaa
    30721 tatttaacgc attttctgca atttctttcg cactcatgtc gttttgagca tagtttttca
    30781 ttgctcgggc tgcagccaac gcaaaattcc ctcctgatcc gatagctaag ataccatcat
    30841 ctggtgtgat aacttctcct gtacctgaaa caagaagcat ttctttatca ttcattacga
    30901 tcagcatcgc ttcaagtttt tgcatagatt gctgtgtccg ccattcttga gctaattcga
    30961 cagctgcgcg ttgtagattc ccgttatatt cgtttagttt gccttcaaat ttttcttcta
    31021 aagtaaacgc atctgcaaca cttccggcga aacctacaac aacttctcca ttgtagatac
    31081 gtcgtacttt ctttgcagtg cctttcatga caacagattc acccattgtt acttggccat
    31141 ctccagccat agcaaatttc ccgtcttttt cgacggcaca gatagtggtt gaatgaaatg
    31201 gtgattcgac catgtttgtt tcctcctaaa tttgttcttt tccttatttt tacgctcttg
    31261 gatggaaaga acgatagttt ttttgtaaac tttcttttgt tacatgggca tagatctggg
    31321 tagtcgataa attggcatgt cctagcaatt cttggactgt ccgcaaatct gccccattat
    31381 ttaataaatg agtagcaaat gtatggcgca gcatgtgagg atggatatca ctatccaaac
    31441 tgcttttttt gatcatttga ttcaagacat attcaattcc agtaggcgtg attggttttc
    31501 catgatgatt cacaaaaacg atatcatgct cttcgtgata ttttgtcatc aatacctggc
    31561 ggccttccct gaaatattct tgcagagcat cttgagcaaa agaacctaga ggagcatatc
    31621 tctctttgtt ccctttacca tggatcaaca tgacctctga atcaaaatca atgtctgata
    31681 ccgacaaact gctacactca cttaaacgga tgcctgaccc gtaaaggact tccagtaaag
    31741 cgcggttcct caaatccaaa ggactatctc ctgctacgct gtcaaaaagt gcttgcattt
    31801 cattttcata aaaaaaacgt ggcagtctca aatttttctt tttgagatga acgtaagaaa
    31861 atggattttc ttttatcact tcttctttga gaagatactg ataaaacgaa cgtaggctgg
    31921 ctatcttgcg actgatagaa tttctgctat agctaggacg atgatcagct aatgcactca
    31981 aatagacacg aaccgtaaaa tattccgcct tcagcagatc agcgtctcca gattcctcca
    32041 aaaaatgttt gaaatggaga atgtcttctt catatgcttc tttcgttttt tctgaatatc
    32101 ctctttcgac aatcaaataa cgcaaaaatt tttgttccca cgtggcttct gtcattttct
    32161 caccttcctt ttgtcccaga gaataattta gcacagcgtt tataaaaaga caaataaatt
    32221 gtcagaattt aaccaatatt tctaagtttg ttcacaattg gcgcaattcc tcacattttg
    32281 tttgagaaat tcttaagaaa aacgcaagaa aaagagcgag actatccgtc tcaccctctt
    32341 catggagttt ccttactcat ttgggattgc agttttttct aattctgttt ttattgcctc
    32401 attagctttt aaagctcgtt gtgcaattgc ttcatatctt gcttttttgt ctcgaatgcg
    32461 ctctggcagt tcaggaaaca gaccatagtt ggcattcatc ggttggaaat gttttccttc
    32521 cgcatgagta atgtagtaag ccatacttcc aatagctgtt tcttgtggaa actcgactgg
    32581 ttccatttct tttgctaagc gtgcggcgtt gattccagca agtagtccgc tcgctgcact
    32641 ttcaacatag ccttctacac cagtcatctg acctgcaaag aacagatctt cgcgtttcgt
    32701 tgattggtaa gtcggtttca gcaattctgg cgaattcata aagctgtttc ggtgcatcac
    32761 accatagcga acgaattcag cattttctaa cccaggaatc atccggaaaa cacgtttttg
    32821 ctcgccccat ttcaagtgag tctgaaagcc cacgatgttg tataaagaag ctgcagcatt
    32881 gtcttgacgc agctggataa cagcataagg acgtttgcca gttttaggat cttccaatcc
    32941 aactggtttc ataggtccga aaagcatcgt tttgaatcct cgctgtgcca ttacttcaat
    33001 tggcatacat ccttcaaaat atttttcttt ctcaaaagat ttaagttctg ccacttcggc
    33061 attgattagt gcctcatgga aagctttgaa ttcctcttct gtcatcggac agttcaagta
    33121 agctgcttct cctttgtcat agcgggactt caaatatact ttatccatat cgatcgtagc
    33181 tttgtctacg attggtgcag ctgcatcata gaaataaaaa ccatctgaac cattgaatgc
    33241 tttgatgctt tctgctaatg gatgagaagt caaaggtcct gttgctacta cggtgattcc
    33301 ttccggtatt tcagtaattt cttcgtttat cactgttact aatggatgct ctttgacttt
    33361 tcgggtaatt gtttcagaaa aagaatcgcg gtcaacagct aaggcaccac cagctggcac
    33421 tgctgtttca tctgccgaag tgattactac cgaattcaat cggcgcattt cttctttcaa
    33481 taaccctact gcattagcca aactgtttcc tcttaatgaa ttggaacata ctagttcagc
    33541 aaaattactt gtgtgatgcg cctcagtcga tttgactgga cgcatttcat ataaacggac
    33601 agggactcct gcttgtgcga tctgccaagc agcttcactt ccggcaagcc ctgctccaac
    33661 aacatttacc attttcaatg aaagaacctc ttttctatta tttttggatg tcttcttcgt
    33721 aatctccatt tacacagact acttgtttac cgcctttgac tttcttctcg accagatatc
    33781 cgtcacattt tggacaattt ctgcccactg gtttatccca agaagtgaat tcacattctg
    33841 ggaaacggga acaaccatag aatagtctgt ttttcttaga ttttcgttca atgacttgtc
    33901 cttcatgaca tactgggcaa gtcacaccga tttcttttac gattggtttc gtattccgac
    33961 aatcaggaaa attactgcaa gcataaaact tcccatattt ccctaatttt atcaccatcg
    34021 gatgtccaca gacatcacaa tcgaatcctg ctggttcatc tttgatttga attttttcga
    34081 ttttttcttc cgcattcgtc agttcttttt caaacggttt atagaaacga tcaaccactt
    34141 tgacccacgc ttccgtgcct tcttcaattt tatccaaatc tccttccatt tctgctgtga
    34201 aatggatatc gacgatttga gggaagaatt cacagattaa tgaattgaca atttctccta
    34261 gttcagtcgg ctcaaatctt ttttgtgtca attttacata gtagcgtctt tggatcgtat
    34321 caagtgttgg tgcataagtg gaaggtcgcc ctaccccgtt ttcttctagt gcacgaatca
    34381 acgtagcctc actaaaacgt gctggtggtt gagtaaaatg ttgttttggt tcaatatcaa
    34441 cagattggac tacatcgcct tcttcaagtt ctggaagaat attttctttc tcttctttgc
    34501 cgtcatctct accttccaca tacacttgca tgaatccttt gaatttgatt tttgaaccgt
    34561 tcgcaatgaa gatgacacca ttttgttcta atgtcacttt cattgtatct aaaatagctg
    34621 gtgtcatctg actagccaca aaacgtgacc agatcaatgt ataaagtttc aattgatctt
    34681 tatctaaata ttgtttgagt tcatctggtg tacgaagcac actcgttgga cgcacagctt
    34741 catgggcatc ttgtgcgcct tgagcatttt tgatctttcg gtgatcatgt ctagaaaatt
    34801 cttttccata cgtatcttca ataaatgctg cggcctctgc ttttgctgta tcggcaatcc
    34861 gggtagaatc agtacgcatg tatgtaatca agccgactgt tccttgttta cccaaagtga
    34921 ttccttcata taattgctgt gctaccatca tggtttttct tgttcgaaag tttaacttac
    34981 gggcagcttc ttgttgcagg ctacttgtag tgaaaggatt cgcagggttt cttttgcgct
    35041 ctttcttttc tactttttta acttcgaagt ctgttccatc aattctagca gtgacttctt
    35101 ttacactttg tgcatctggt aatttctttt tcttaccgtc gattccccag aaatttgctt
    35161 tgaatttctt gcgagctttt ttaaaattac cgtcgatgct ccaatattct tctggaacaa
    35221 attctcggat ctctttttca cggtcaataa taatttttaa agcgacagat tggacacgtc
    35281 ctgcacttaa ccctttcttg accttacgcc agagaatagg actgatcgaa taaccaacga
    35341 ttctgtctaa ggtacgacga gcttgctgtg catctactaa atctacatcg atcgttcttg
    35401 gttccttaaa agctgctttg actgcgtctt ttgtgatttc attgaagacc acccgatttt
    35461 tttctttcag atccaaccca agtaggtacg ctaaatgcca agcaatcgct tctccttctc
    35521 tatccgggtc acttgccaag taaacttttt gagctttttt tgctgcggct ttcaggcttt
    35581 tgatgacatc gccttttccg cgtatagaaa tataatgggg ttcataattg ttttcaaaat
    35641 cgatacccat tttacttttc ggtaaatctc ttatatggcc aacactggcc attactttat
    35701 agtttcgtcc aagatatttc tcaattgtct tggcttttgc aggtgattct acaatcacta
    35761 aatatttata cgccattact gaatggactc ctttccattg tcgtgttcct actattaaaa
    35821 gaggattcat acaaatcgta gctaatcata tccattcaga aaacgtttgt caagaaaagc
    35881 aaatgaaaag tatggtgtta ttctttaaat tctgccaaga tatcttcacc cgaaaccgtg
    35941 caaactgcac cgtcttggat caaatgatga catccggtag aatgttctgt taaaatattt
    36001 cctggaacag aaaaaactgt tcttccaaga tccaatgctt gctgtgctgt tatcagagag
    36061 ccgctttttt tcttggcttc aaagacacat gttcctttag acaaagctgc gataatccga
    36121 tttctcattg gaaaacaatg ctttttcggg ccggattgag gaggatattc actcaaaaga
    36181 agatgatcat ttgcaatcac ctcttgcaag tcacgatttt cagcaggata gacttgctct
    36241 atccctgttc caatgactgc gattgtccgt ccaccatgag agattgctgc ttggtgaccg
    36301 tatgtatcta tccctttcgc gcagccactg acgatcacat atccagcttc tatcactggt
    36361 tttagtaaat aataaactgt ttttttggct aaagcagaag tgtgtcttcc accaacaacg
    36421 cttaacatgt tacaagaaag taaagataga tcaccattat aaaacagtac aattggcgga
    36481 taggtcaagt gaagcagctg agggggatat ttgggatcaa agcaagtgat aaacgactgt
    36541 ttcgattgga ttttgcccca gttagcgtga atttcctgcc aacttttgcg aaacagctcc
    36601 cggtgtttgg ttattttacc tatcttaatg atgtcttcaa atccgatttc tttataagga
    36661 tactgcatca tccagttagc aagtgcccat tttccttgac tactgattcc ttttgtataa
    36721 gcaagtttca ataaattttc ttctatttga tacatcataa aaccgccttt cgtctctctt
    36781 tctaataaga tacgtaaaag cggctgtttt ttattgtaaa tattttttta caggtgcaaa
    36841 acttttacga tggattggcg taattccttg tcgttcaagt ccttctaagt gttcctttgt
    36901 tccataacct gcattatgcg agaaaccata tccaggataa agcacgtcat attctttcat
    36961 caattggtct cgatatactt tagcaatgat acttgcagca gcaatcgaca cagatcgtac
    37021 atcccctttg attatttttt cctgctgaat aggcaaatcc aaggtcatcg catcgatcaa
    37081 caaatagctt ggtacaatgg acaatttttc tactgcttgg atcatcgcta atttacttgc
    37141 ttcataaata ttcacatcat cgattgtctg ctgatcaacg atcccgatcc cgattgccag
    37201 ggctttttct tgaacttgtt gataaagaag ttctcgcttt ttctctgata attgtttgga
    37261 gtcattcagc cctaatatga tctcattttt cggcaagata actgcagctg ccacgacagg
    37321 tccagctaat ggtcctcttc ctacttcatc aatgccggca atccattggt gaccttgtgc
    37381 gtacccttgc ttttcaaagc aaaacatttc ttcatatttt tccttaatta atgcttcctt
    37441 tttcaatcgt cgttcaaaag aagccagtgc ttgctgcacg cctttgcgtg gatcatttct
    37501 taatgattct agtgtaggat catctattct ctgtatgctt ttcaatcgtt ctttgatact
    37561 ttggatggat tcagtcatca cttttttgct ccatttcttc gcaacgatcc agtgtgtatc
    37621 gtccaagttt tccttgacga atatcatgca cgactaattc gctgccacga tcatagtctt
    37681 ctttataccc acgttttgct gtaatatcca tcagtaattc cggtgccaat ttttcttctt
    37741 gctcgattga taaaccataa cgatcgctga ttcttcctga ataatatcgg gcaaaaaagt
    37801 ctaatccgta aatcgctaaa tcatctaaat ggacaagctg gtctttgatc gcgcctgtca
    37861 gcgctagttt tttgccgatt tcttcatctt caaatttggg ccataaaatc cctggtgtgt
    37921 ctaacaattc caactcatta cctaaacgaa gccactgctg accttttgtt acgccaggct
    37981 tatttcctgt ctgtgcaatt ttcttgccta ctagtcgatt catcaacgta gatttcccaa
    38041 catttggaat acctaagacc attgcccgaa tagcgcgagg cttgatcccc cgagcagcat
    38101 ctcttgcccg tttttctttc aatgcttctt tagccgcagg tactagacct ttaattcctt
    38161 tactttcttg tgccgtgata gctaatgcaa gatggccttg tttacgaaaa tattcttgcc
    38221 acagctttgt ctgttgtgga tctgccagat ccgctttatt caataaaaca aggcgaggtt
    38281 tttgctgaat gatctgatct agcattggat tacgagaaga taaaggtaat cgtgcgtcta
    38341 ccaattcaaa tacgatgtcc acatatttca ttttttcaga aacttctcgt cgggcttttg
    38401 ccatatgtcc cggaaaccat tggatggtca ttgttctctc cattcctttc ataccggaat
    38461 attccccggc tttacttgtt tttttctttt tcaatataaa ttcacttttt tatt
//
LOCUS       DBGZHO010000020        38221 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.020, whole genome shotgun sequence.
ACCESSION   DBGZHO010000020 DBGZHO010000000
VERSION     DBGZHO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.020"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(578..1522)
                     /locus_tag="ACN3HL_001225"
     CDS             complement(578..1522)
                     /locus_tag="ACN3HL_001225"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HHC8006115.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1818..2762)
                     /locus_tag="ACN3HL_001226"
     CDS             complement(1818..2762)
                     /locus_tag="ACN3HL_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHC8006116.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2983..4197
                     /locus_tag="ACN3HL_001227"
     CDS             2983..4197
                     /locus_tag="ACN3HL_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8006117.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4219..6234
                     /locus_tag="ACN3HL_001228"
     CDS             4219..6234
                     /locus_tag="ACN3HL_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HHC8006118.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6317..7690)
                     /locus_tag="ACN3HL_001229"
     CDS             complement(6317..7690)
                     /locus_tag="ACN3HL_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHC8006119.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7716..8000)
                     /locus_tag="ACN3HL_001230"
     CDS             complement(7716..8000)
                     /locus_tag="ACN3HL_001230"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8006120.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(8002..10017)
                     /locus_tag="ACN3HL_001231"
     CDS             complement(8002..10017)
                     /locus_tag="ACN3HL_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HHC8006121.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10196..10501)
                     /locus_tag="ACN3HL_001232"
     CDS             complement(10196..10501)
                     /locus_tag="ACN3HL_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HHC8006122.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10590..11621)
                     /locus_tag="ACN3HL_001233"
     CDS             complement(10590..11621)
                     /locus_tag="ACN3HL_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8006123.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11828..12703
                     /locus_tag="ACN3HL_001234"
     CDS             11828..12703
                     /locus_tag="ACN3HL_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHC8006124.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12855..13697)
                     /locus_tag="ACN3HL_001235"
     CDS             complement(12855..13697)
                     /locus_tag="ACN3HL_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HHC8006125.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13789..15666)
                     /locus_tag="ACN3HL_001236"
     CDS             complement(13789..15666)
                     /locus_tag="ACN3HL_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HHC8006126.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15663..17084)
                     /locus_tag="ACN3HL_001237"
     CDS             complement(15663..17084)
                     /locus_tag="ACN3HL_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HHC8006127.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(17087..20476)
                     /locus_tag="ACN3HL_001238"
     CDS             complement(17087..20476)
                     /locus_tag="ACN3HL_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HHC8006128.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDDYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20733..22124
                     /locus_tag="ACN3HL_001239"
     CDS             20733..22124
                     /locus_tag="ACN3HL_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006129.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22197..22844)
                     /locus_tag="ACN3HL_001240"
     CDS             complement(22197..22844)
                     /locus_tag="ACN3HL_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8006130.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22852..23538)
                     /locus_tag="ACN3HL_001241"
     CDS             complement(22852..23538)
                     /locus_tag="ACN3HL_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006131.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23544..24617)
                     /locus_tag="ACN3HL_001242"
     CDS             complement(23544..24617)
                     /locus_tag="ACN3HL_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006132.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24839..25513
                     /locus_tag="ACN3HL_001243"
     CDS             24839..25513
                     /locus_tag="ACN3HL_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8006133.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25518..26858
                     /locus_tag="ACN3HL_001244"
     CDS             25518..26858
                     /locus_tag="ACN3HL_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HHC8006134.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(27007..27993)
                     /locus_tag="ACN3HL_001245"
     CDS             complement(27007..27993)
                     /locus_tag="ACN3HL_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HHC8006135.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28717..29748
                     /locus_tag="ACN3HL_001246"
     CDS             28717..29748
                     /locus_tag="ACN3HL_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006136.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29857..31389
                     /locus_tag="ACN3HL_001247"
     CDS             29857..31389
                     /locus_tag="ACN3HL_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HHC8006137.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            31528..32340
                     /locus_tag="ACN3HL_001248"
     CDS             31528..32340
                     /locus_tag="ACN3HL_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HHC8006138.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            32330..32815
                     /locus_tag="ACN3HL_001249"
     CDS             32330..32815
                     /locus_tag="ACN3HL_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHC8006139.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32838..33383
                     /locus_tag="ACN3HL_001250"
     CDS             32838..33383
                     /locus_tag="ACN3HL_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HHC8006140.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33456..35099)
                     /locus_tag="ACN3HL_001251"
     CDS             complement(33456..35099)
                     /locus_tag="ACN3HL_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HHC8006141.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(35228..37456)
                     /locus_tag="ACN3HL_001252"
     CDS             complement(35228..37456)
                     /locus_tag="ACN3HL_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8006142.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(37489..37968)
                     /locus_tag="ACN3HL_001253"
     CDS             complement(37489..37968)
                     /locus_tag="ACN3HL_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HHC8006143.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        11167 a         7211 c         6942 g        12901 t
ORIGIN      
        1 ttcataaaaa tatggaaaat atggattaat tttgaaataa ttgatttaaa aggaatacaa
       61 aagagtgaat agtaggaaat agtggtttag aactagtggg ctgatttttt atatatttta
      121 gtttacataa tatatattat acaaagtaga tttaaaaaat gataaacctc tctcgaacgg
      181 ttttttatca aaaatcgtca tttttccatc aaaatctgct tatgcaaaat tataaaaaaa
      241 ttttgcagtt tttcttactt tttttgtcgt ttaattgaat gataaaaacc agtttcttta
      301 ttcagttaat caaatatgaa cgaattagat atgaatcatt gtatttgccg ttgcggaagg
      361 attttttaat taaccacaga taaacattga taacgattcg cttattgtaa tcaacagatt
      421 aaatttcata tgttcatatg tacggataca ttttcggacc gattaatttt aaccattctg
      481 tttatttgct tacctattag atatcaataa aaaactgctt aacagctatt tcagctgtta
      541 agcagtttta ggatttttag ttcatattca ttgtttctta taatacagtg ttcaatactt
      601 ctcttaaagc acttgttgat ttgctgaaca ttgctttttc ttcttcgttg attgataatt
      661 caacaacttc acgaacacca ttttcgtcaa cgattgatgg cacacctgta aagatatctt
      721 tttcgtcgta ttcaccagtt aaataagcag atacaggcaa tacagcttgt tcgttattca
      781 agatagcttt tacgatacgt gcagtactca taccaatacc atagtaagtt gcttttttac
      841 gatcaatgat ctcataagca gcattacgga ctttatcagc aatcacatct aattcatctt
      901 gggcaatacg atggtctttt tctacaattt caaacactgg tttaccaccg acagttgtat
      961 gtgaccatgc agcaacttct gaatcaccat gttcacctaa gatatagccg tggacgctgc
     1021 gtgggtcaac ttttaatttc aatgcgattt ctttacggaa acgagttgta tccaatgttg
     1081 ttccagtacc gataacacgt gatgttggca gaccagattc gttccaagcg atatatgtca
     1141 aaatatctac tgggtttgaa gcaacaacga taataccgtc gaatcctgat cccatgattt
     1201 cttttacgat ttggcgcatg attgacgcat ttgttttaac taaatctaaa cgagattgac
     1261 caggtttttg gttgatacca gctgtgataa caacgatatc agcatcttta cattcttcat
     1321 agccacctga ccatacagcc acattttcat cgccccaagc cataccatct aaaaggtcca
     1381 atgcttcccc ttctgctttt tcttgattca catcgatcaa tactaattca ttagagattc
     1441 cttggttgat cattgcataa gcgatacttg ttccaacaaa acctgtaccg acgattacta
     1501 ctttacgact tgtttttttc atgaataaac agctcctttt cataactatt tgttactttc
     1561 atgaaaagta tagtcttgtt tattcatttt atcaacatgt taattataat agttgttatt
     1621 ataatttttg atggaaacga attcctgaat acgcataaca gataaatgac aaatgtttac
     1681 acctatatcc cctgataata caaccaaaag tttagaactg aaaataaatc caaaaaaatt
     1741 cgctgcaacg atataataag acagcaatcg cacctaaaac aattttcctt catatgcttt
     1801 agtgaaagat tttcttctta atgtttattt ctccattcat tgggagtaca tgttgaatac
     1861 ttcttgaata atttgaataa agaagtcgtt tgtttatatc cgatacgatt agcgatttct
     1921 tccaacgaaa aactcgtttc ttgaatcagt tccaacgcaa agtcgaattt tttctttaga
     1981 accagttctt gaaaggaagc atcaaaatac attttcaatt tattactaag atagaccgga
     2041 ttgtagccaa aatgagctgc tgtttctttt aacgtacaag aagtaaaatg cttatcgata
     2101 taatctaata ctctaagcat ctcattttct gcgcatccat ctgctgatga aaagctttgt
     2161 tgttctaata aatgagtcaa ttcgatcagt aatagtgatg tatagagatt taacgaacgg
     2221 atcttatgac tgtatgtatc aaaataaatc aacagcatat tttcaatcaa atgcgtcaaa
     2281 cgacttgttt ttccgccgcg aaaatgaatg aattgtgtat gttccccttt ttcttttgat
     2341 gcatttatca aaaaagaaga aagtagatta tttgtgcttg ccaaatgatt caatatctct
     2401 gtagataagg tttcttcttt taataagatg ttgattaaaa tatcctcttg ccctgtgtat
     2461 tcgattcttt gagtagcttc tttatcaatg atcaccacgt cactttcttc catctctatc
     2521 ctttctccat taataatttg taaacatgta ccgctataca tataattgat ttcaacaaaa
     2581 tcatgtgtat gctcgggaac ttccgcatat cgacggtgtt tactgatatg aatatttccc
     2641 tgttgaaata gatcccctcg gtggattttt ggcggtgtct gaagatggta agctaagttt
     2701 aaatcattga tattcattcc ttgttcacgc tgcagagttt cgattgattc ttcgttacgc
     2761 aaaaaaaatg tctaattcag ctagttccaa ttgactccct cctttttgta agcggtttct
     2821 ttcgcttatt agttcacgct gtactgctat tatatgcaaa gctatttttg gtttcataaa
     2881 gactttctat ggttgggaca tgaacttcct gtgattccgc tattgagaga ataaccactt
     2941 catactatat ttttgataag cgcttacaaa aatgaaagga acatgcttat gaataaaaag
     3001 atgatgaaat tttctctgct gtcagtctct cttattttga cttctgctgg tgcagtcacg
     3061 tctgcaattc ccagtatgtc agctacttat gccacgcgtt ctttatctgc tgttgaatta
     3121 ttaacgactg ctccctcttt tatggtcact atttttgttt tgattagtag ttttattgct
     3181 aggaaaatcg gacaaaaaca aactgtgatc atcggattag tgattgcatc gatttatggt
     3241 atcctccccc tcttctcaca aagttacagt attgtcttag cttcaagagc tggactaggt
     3301 attggctttg gattgatcaa ttctttggca gtcagcatga ttgctgcctt ttatcacgga
     3361 gatgaacgag cctctatgat tggttttcaa agtgcatttc aaggatttgg tgcagcttta
     3421 atgacatttg ttgcaggaca gctagtacag ttcggttggc aatatacctt tttagtctac
     3481 gccatcagct tacctattct tgtcttgttt gttttgtttg ttcctacacc tgaaacaact
     3541 gaacttcaat cacatggcac agccccaaca agacaagtaa tcaaaacgaa tcctaaaatg
     3601 attagttatg gtatttttct cttgctggtc atcgtggtat ataatgctgt atcgattaaa
     3661 ttagccacag tcctgacgac ttattctcta ggaaacgaaa ctaatgcagc gaatatctta
     3721 acaatcatgc aattggcaag tatggctgcc ggagtttgtt ttggctggct tcagacaaaa
     3781 gcacatcgct atatgcttac actttcttta ctactgatgg gaatcggctt tgtattgatt
     3841 gccactgtga taaacctgta tgtgattggg tttggtgcga tcctaacagg aatttctttt
     3901 tcgttattca ttccttactt attcaaccaa gtaagtatcc aagcgcccaa gtacgcggag
     3961 agtttcaata cttcaatctt attggttggc gctaatttag gtactttcat tgcaccatat
     4021 ggtttgctct ttctctcttt tgcttctctt gggagtaaaa cacttgctgt tttcgtcaat
     4081 ggcagtatct tgctgttgat tagcgcgctt attagccttc tagtagtaca caggacgaat
     4141 agaaagacag tgataagagt agatgaagaa ataaaagaac aattgacaac aaaataaatt
     4201 tgatggaggt cgtgtaaaat gacaaatgaa aaacataaag atagatggct ttggtatcct
     4261 ggagactttg agatccgcca tggactgcta caaaatttcc aacgggaaga acgaggtttt
     4321 gactggccag cgtactggta catggatgat tgccatcgga acgtcaagtt taagagatat
     4381 tactttcttg atcaaccttc catgtttaaa gtgacgatcc aaggagttgg gtatgtagaa
     4441 attaatggac aaaaacatcc atgtggaaaa tggctgactt gtccagctgg taaagcaaaa
     4501 attcgtatct ttgtaggaca tacatcaggg ctaccagcga tgtttatcga gggagacgaa
     4561 gtaaaatcag atattggctg gacagcaagt aattttattg aagaatatcc agctggctgg
     4621 agtccgcttt atgtcgatat cgcaaaagat ccaaatcaaa tctattatca aaaagaatgc
     4681 gtccatccag tcactgaaac ggagattggc ggaggaatct tattcgattt tgggcgagca
     4741 gtgaatggct gtgtagaact aatatctctg gatgaccata tcgaatctat cactctatgt
     4801 tatggagagt ccgatgtaga agctatggat atcgattatt gctactataa gcaaatagga
     4861 atgacaagaa aaatgaaagc tcgtaaacgc gcttttcgct atttgtttat accagaggtt
     4921 tctactggaa tggttcaact tcaagttttt catgaatttt tatctctttc gaaacaagct
     4981 gctttttcaa gcgattcttc tttactgaat cagatctggt cagtatcaga agaaaccttc
     5041 aagttatgta gtgatttgtt ttttatcgac ggtatcaaac gagatcgctg gatttggtct
     5101 ggagatgcgt atcaatcatt catgatcaat caatatcttt tttttgacga ggaaatcaat
     5161 aaacgaacga tattagcatt aagaggacaa aatgaaatca agcagcatat gaatactatc
     5221 gttgactatt cgatcttgtg gttgattggt atcgaaaacc actatatgat gacgaaagac
     5281 tatgaatttt tacgcatcgt ctaccctaag atgcaatcat taatgagata cttgatggag
     5341 caaacgaatg aattagggtt tatttatggg agagcaaaag attggatatt tattgattgg
     5401 tctgaaatgg ataaagaagg aacgcttgct gcagaacaag tcttattact gaaagcctat
     5461 cattccatga tcacttgcgg agatatctta gctgaaacat atggagagaa cgaaaattat
     5521 catactcatc tctatcaaga aaaatatcaa ctattgaaac aaaacctatt tgactacttt
     5581 tgggatgaag aacttggcgc ttttatcgat tgctatgaat ctgggagaag aaatgtgacg
     5641 cgtcatgcga atattttcgc tgttttattc gattttgcta acaaagacca acagcaatcg
     5701 atcttaaaga atgtcttatt gaatgacact atcacacaga ttactactcc atatttcaaa
     5761 ttctatgaac aagatgcttt atgcaaactc ggacagacga atatcgtcta ccaaacgatt
     5821 cttgattatt ggggagggat gttatctcat gatgcggtaa ctttctggga agaatacgac
     5881 cctactcaaa caggaaatga aaagtacagt atgtatggag atccttatgg aaaaagctta
     5941 tgccatgcat ggggagcaag cccaatctat cttttaggac gctattttat cggtttgtat
     6001 ccaacaaagc caggttatga agaatttatg atacaaccta atctagattc atttgaaaca
     6061 ctgaattgta cgctacctat caaagatgga aagatttcgc ttgaaaaaac aaaagataag
     6121 atcgtgatta cttctgatag aacaggcgga acagtgaaaa tgaatggtaa aagttatcct
     6181 cttctagcaa aacagccact tgtcttaaca agctattcaa aaataaatgc ataaaacaaa
     6241 aaactgcttg cgacatatca gaagacttta aatcttcttc tgatattgtc caagcaattt
     6301 ttattttgaa gtttgcttaa ttctgttctt tagaaacaat gtttgttctt tttccggcaa
     6361 aaagaaagct agataatacg acaagtaaaa agaaagcgat gattccaact gtcaaggcta
     6421 tttgaccgta ttctcctagt ttcccaagta caagtcctgg tactagataa tcagtatcgg
     6481 caaatgtaga agaagcgatt ttaagatctc ctaatactgg aaggataaat aatggcagcc
     6541 aactaatcaa taagctattg aaagcagaac ctaataccgc ccctcttcta ccgccagtcg
     6601 agttgccgaa gacaccagaa gcagctccgc agaagaaatg tcctactacc ccaggaatga
     6661 taactgtagt ttgcaagcct atcatagcaa acatggatag tgttcctaca aagaagctaa
     6721 caaaaaagcc aattaataca gcattaggtg catatggaaa aacgatagga acatctaatg
     6781 ctggtttaga atcgggtacg agttttttag caatcccttg gaatgctgga acgatttctg
     6841 ccaacaccat tcgaacccct tgaaggacga taacaaaccc agctgtgaat gttccagctt
     6901 ggatcagtgc aaagattaca gcgttgtctc cattgcttag ttctctttca acaaatccag
     6961 gaccagctaa caaagcaagt gcgacatata cgatcgacat caagagcatg atcgatacag
     7021 tagaatctcg caaaaagctg aaacttttag gaatctttat gtcctctgta gaacggtctt
     7081 tgtttccaaa aaactttccg atccatccac tagaagcata accgatattt ccggtatgcc
     7141 ctaacgcaac ttgattgttt ccagtgatgt tcttcataaa cggttgacaa agagcaggcg
     7201 taatagttaa tagtgttcct tcgaagaccc cgcctaataa gatcatccac aaatttgcag
     7261 taaaccccgc gcttactaaa atgactgctg ttagacaaga aacataaagc attgcttgac
     7321 ctgtaagaaa aatgaattta tatcttgtga atctagcaag taaaatattc acgatcatcc
     7381 ctactagcat gatcaaagca gtaggtgtac cgtattgttg caaagcaatc gccactactg
     7441 cttcattgct aggaactact ccttgagtat gcagagctgt ttggaacatc gaagcaaaag
     7501 gggttagtga attactgatt aaaccagcac cgccgatcag tactaggaat ccgacaaatg
     7561 ttttgatagt tccttggatc acttctgaaa atttcttctt ctgaagaacg agaccaagca
     7621 gtgcaatcaa agaaacgagg atggagggct gactgacgat tgacacaaac aaattcaaca
     7681 atttatccat tgatagttcc tcccttgaat catttttatt cttttgacaa gatcttcgtt
     7741 actttttctt ttacttcttc gctgtcaatg atcgattgca aaggtacgag cttttcatca
     7801 ggtatagaag ttagcgtatc tttcaaagaa tgctcaatga agaaataatc agccatatcg
     7861 ctagatacac ttccaacatc cgtatgactt acttcaaact cgtccacatc tgctccaaga
     7921 tctgcaagtg cttgtttgat gttcatctct accataaaac ttgttcctaa tccactttga
     7981 catactgcaa aaattttcat atcattcgtc tccttttctt atgatcgcta atatttcttc
     8041 ttttgttgat gcgtgtaata aatcttgaag attttgttta ttagaaagta gctttgttaa
     8101 atttgccaaa gcccgaagat gtgcctcatt atcgatagca gctaaacaga tgaacaaact
     8161 aatgggatgg gctggattat caagcagatc cacaggttgt tgaagtttca gcaaagacat
     8221 ccctacttcg tttacgccat cttctggacg agcatgaggt aatgcgatgt gatcgccaat
     8281 atggataaac gcaccatact gctccacgcg ctcgatcata gctttgatat aactttcttc
     8341 tattttattt tctgataata gcggctgtgc ggcaaatgtg attgcttctt gccagttttt
     8401 tggttgatcc gataattgga tcatttcttc tgttaataat tcagatagca taggacgttg
     8461 atcctccttc ttttctaaaa gtttgttcat tttacgattt aatacttgat agagcttttc
     8521 ttcgtctacg ccttctttta attcgatata aggcagtagc gccgacaaca attcttgggc
     8581 agaaggcatt gaaaatcctg gtatcagcca atctctttgt acttgattga tcagctgatt
     8641 tttttccaag tcagtcatga ttggatgcag aacatagaga gactttttct tatcagtaag
     8701 tgtgagaggt acagtagaaa aaataatatc gtaagaagtt tcgtcaacct cgtgtaagcg
     8761 gtcagctgaa ttagtctctg taaaaaagat catcgggaat aattgctgaa gttcactttt
     8821 taagatcaat gaagagctaa tgccacttgg acagacgatc acggctctta tttttctatt
     8881 tctttcttct gcgtccgctt ttctgatctc tccgccaaat agtatagtga aaaaaccaat
     8941 ctcttcttca gggatgctct tccctattcg tctttctaac ggaagtaatg cttttcttgt
     9001 catttcgtag atggaagcat attgatgctt aatttgatcg atcatcacat taggtaaata
     9061 aaaagaatag gaaatacgaa aataggcagg gaccaagtga taaaagacat tcatcaataa
     9121 ttcacgaaac gaagcaaatt ctacggccat caggaattcc atgcgatgga tgacttctga
     9181 agaacattcc agcaaaaaat caagtgcagg ctcctggaca tctccttcaa cgatcgatgc
     9241 taagcaaaga gagaaaaata taatctccga attttgatgt tcggaatagc caaggccagt
     9301 caatacttgt cgactaatgt cagtgactgc aagagaagcc aacagttcag catcttttac
     9361 cagttccatg gatgtttttc caattcgaat ggttgtcaaa ctcaaataat aagctaattc
     9421 atccattcga tttggtgcga atcgaagatc tgatagtgaa atcgttttat ctagcaaatc
     9481 tctaactttg gcgtaataat caatggaaag ggttgcggtt aaatacgtga gcccaaatct
     9541 tccagcaagt gactgcatca aacgagcagt gcgatttttt gcttctcttc ttaatattgc
     9601 ttctgaccct agcagcctaa aaccagtttt cctagtatac gacagctgac aatcttccac
     9661 ttctaattca tttcttatct ttttgatatc tgacaggact gtccctttag aaacctgaag
     9721 aaaatcttga aaatgaaaaa cagaaacaga cgttgcagtc gaataaacca tcaaataaag
     9781 aagatctctt cgctcttgtt cggtatacac agcttcaaat cgagtaatat ccaaaaattt
     9841 ttctgcccag tcgattgctc ggaatttctt tatacggata cgggtatcat ccacatattc
     9901 ggcaaaagga gttaattgtt tgatcgcctc gcttgtattt acttcgatga tctctgctgc
     9961 tttttctaga ctgatttctc ttggtgtttt caggagataa ctaattttgt agttcacagc
    10021 gctgttcacc tcctacttat attctagtat ggtagcgctt ttaaatcgag gggtgtttgg
    10081 tacaacttac agttggattt tttttacgac tgtaccgaac gatttctatc gaatggatac
    10141 agaaaaaaag caggtgacca aatgtctcct gcttttatga attgatttcg tccgatcaat
    10201 gatgatcatg tttatttttt gaggtcagtt cttcaaattt ttctttgaca tcttcaaccg
    10261 ctttttcgat atctttttca aagtgattgg gctcattagg ctttgtttcc tcttctacag
    10321 aatttgaacc agataaagct gtttctttat tttctgtttc accagagttt gtgccagcta
    10381 atgattcttc tttgtcttct gtttcaccag aattagttcc tgctaaagcc acttcttctt
    10441 ctgttttagg ggccattgaa cctcttaatc gtttgtgttt ttcaccgtca taatttgtca
    10501 tgttggttcc tcctagtagt tctatacttt ttcatcgtac aataagacag tttatgcgtc
    10561 aaaaaacaaa cccgattctt acaaatatgt catatttttc cttctgattc ttgaatgctt
    10621 ttgattcctt cttccaaaat tttcatttgt aagattgttt cttcatcttt gatgactttt
    10681 tctgcgccat taactaatgt ctcgtaaatc ccttcgtaga cacggctgta atcaccaacc
    10741 tcggaaatta ctttttcttc atgataactc ccttgttcat ctatataggt caatacacca
    10801 taatgttcgg gcaaatcgat accaaagtct tcatgatcag gcatgtaaaa cattttcaga
    10861 tgttcttctt gtcgatcttt tgtttgtttc acgaacatcc ctttttttcc gtaaacgacg
    10921 aaacttggac gttctttgat gcggaaataa ctggatttta tcgaaatttt catatttcca
    10981 tagaaaaaat ccagatcgaa gtaatcattc attcgtcctt tccctaaaag ttgacgtaca
    11041 tcatagctga tatcatctgg ttcgccgaaa taagaaagaa cttgatctac tgtatgacaa
    11101 gcatgtccat ataaatagct gttcgcagta gaaaattcat gcgtattttc tggtacttcc
    11161 ggtctgaaat aatcataatg catttctact tctaaaatat cccctaattt tccgctttcg
    11221 attacttttt ggactgtcaa gaagtcagaa tcgaaccgtc tgttttggta acattggata
    11281 aatagacctt tttcttttgc taatgcaaat aactcttctg cttcctttga cgtttctgca
    11341 aaaggtttct ctactagtac attcttacca tgttcgagtg ccatttttcc atattcataa
    11401 tgaaattgac taggtgtagt gatgacaact aattggatct caggatcatc ccaaagatca
    11461 gacagctgat cagtatattc gatgtcttcg aatgttttcc acactggttc agatggggaa
    11521 aaaatttttt tgatattgat tttgttcgta agttttcttg aaaaaggcaa atgatagcga
    11581 tttgtactct ttccattgcc aagataagcg attgtaagca tgagtggtgc ctccttttat
    11641 tgatgttttc agtatatcct agaaaagcgc agaaagtatt tataatagct attctggtaa
    11701 aaaagttcag aaaaacactt gttatcattc ggtttggtga aattaatgtt caaagtaagg
    11761 ataaaaatca aaaagatagt agcggaacca agtgtttatc agtaagatag aatttggagg
    11821 tcagatcatg cttattgaag aaaaactaac aaaacaagag ttgtttacca cgacagagaa
    11881 acggattgtc gattacatcc gtaggaatat cgaagctgca gtctacatga cgattgaaga
    11941 attagcaaaa gctacgtata cttcccattc agctatcatt cgtttatgca aaaaaatggg
    12001 attcagcgga tttaaagaat tccgtttcga gctggggcgg gaagttcatc aattgattgc
    12061 tcagttcaat caaacgattg atcctaattt tcctttttca agtgaagata gcactcagca
    12121 aattgcaaag aaaatggcgg atttatcgat ccagtcaata aaaaaagcac aattgcagat
    12181 tgaacatgaa gatttagatc aaatcggtaa agtattgaac aaggcacagc gaatctttct
    12241 ttttgcaaaa ggtgattctc aaatcacggc aaggaaattc cagaataaaa tggtcaagtt
    12301 gaataagttt ttgatcatgg ctgaagaata cagtgattct tcttggaatg cagccaattt
    12361 gactagcgag gattgcgcca tttttattag ctacagcggt cgcatccatc attatgaacg
    12421 aataatgacc tatttgaagc atgtagaggc ccctaccttg ctgattaccg gaaatcagca
    12481 ttcagaaatg gccaaacagg ctgatatgtg tcttgttata tcgcaggagg aatatgattt
    12541 tgctaaagta gcgactttct cctctcaaat tgccttcgat tacgtattaa atacgttatt
    12601 ctcagtgata tattctcaaa attttgaaga gaatatccgc aacttgaaaa acaaacaaga
    12661 attgatgcaa aaaggccttc ttaaagaata tcggaaaact taagaaaaga tcctcattta
    12721 gtaataagaa agatagtgtt tgataggctc tctttgatat catcataaaa acaggctgaa
    12781 gttttctttt tcaaacctca gcctgtttgt ttacggaacg attcgaatag atatattata
    12841 gaaatgagga atagctaact tctgtttctt attttgaacg attgacgaaa aagatatata
    12901 agaaggagga aaatcagtat acatgcagct aacaatccat acaggaaaaa tcgtttgttc
    12961 tcggatactt tctgtacttc tttttgaact tcttttgcat gataaggaac ccggtgccct
    13021 ctgacaagta agcgatgact gttgaccata taaggtgtac aagttaggag tgtcacgaaa
    13081 tcctgccctt tttcgattct cagatctttt gtatcagtcg gttctaccgt cttgatctga
    13141 tcgacttgat aagcgagtgt ccgtccattg atttcgatat agaaagaatc acctaaagtc
    13201 agtttcggta agtctgtgaa caactttgct tgaggcagtc ctcgatggct ggaaataacg
    13261 gcatgtgtat tttctccccc cgtaggataa gacgttcctt ccaataatga ggcacctttt
    13321 tctagcagca cagtattcgt ttcatcaaaa attggcaaat ggacattgat ctcagggatc
    13381 gtcaaaatac cgatcgtatg tttctcaaaa taggttctat cctttttcgc aggttctttt
    13441 ttcttagtaa agggatctgc acctggattt ccaccttctt ttgctaattg ctggtttttc
    13501 tttgtcatgt tttcttggat tttagccatg acttcttcat tttctttgac cgcttgttgc
    13561 tgataatgag agatgatctg ctgatccaga taattattca gcgcgtcgct aacaaatgga
    13621 taagctagta tccctattcc tgagagaagc aagaaaagca tcagcagatc tagaagtttc
    13681 cttttctttg gtttcatttg tgttctcctt gtgatgactg tttgataata aaagaaaaag
    13741 gagcatttgc gtaatccgct gctccttttt ccaattcttg caaaaagact aaatctgact
    13801 gtgcttgcgt ctagcaaagt acagtccagc aatcagtaga aggactactc ctgcaccgat
    13861 atacacatag attcccttac cgcctgttga aggaagtgta cctttgtgtt tatttggtat
    13921 tttttcagga gaaatcaact gtcctgctgt tacataagat tgttcatcga tagtaaatgc
    13981 tacacggttt gttaatggaa catatttttc tggcgctttc gtttcttcca gatagtacgt
    14041 gccatatttt agacctgtca catcgattaa accgttactt gtggttgtaa aaaccgttgc
    14101 tgattctttc gccgataccc agctgacggc ttttgtggat gggtcgatcg ataaatattt
    14161 cgctgtgtca ctatcttgat cacgaacgac gaattctgct ccagcaagtg tttggtctga
    14221 tgtaacgtca ccatctactt taacaaatcg tttgccccca gtaacgacat cgactgacgg
    14281 tggtgtttga tcatttgtat gcccgttatc gacatttgct tggttagaaa atcctttggt
    14341 tggatctgct ttttcgttca aatgcatata gtaaacgaat ttcaatgtac cgccaggagt
    14401 taatgaagga atataattcg gatcaactga aaccgtgaat ccgtctgttt gctcagtgac
    14461 agaataattt actgggtcga tttctttatt tccatcatat aaggcataag catacgttcc
    14521 tgaagaatca ttatcaaatg ttaaagcagc gtcatgagta tcgataagtt tgaatgttgt
    14581 gtacttgttt tgcgttcctt ctttatcagc gatacctaat gggatattga cagaaatctc
    14641 atattgaatt ttttcaccga ttgcgacatc ttttccattc aattgaggtg ttgttttatc
    14701 aactttagac gtatcatttt tgatggtctt ttctactggt gtttggctat ttgccaggat
    14761 ctcaaaaggc gtgattgttt gcttttcaat catttccgca ttatcaggag cttttacttc
    14821 ttctaaatta tattttccaa cttctaaatg attaacgatc aactggcctt tttcaataga
    14881 tgcctcggca aagtcattgt tgccgatgtc ataagaatga ccagtaatga aatgtttggc
    14941 tttggtttga tcagttgtcc aagtgtacaa tccatctgtg acactttgga tgtatttttt
    15001 gacgcttggt gttccttctt ctttagaaat aataaattct gctccattta gtgcttcgtt
    15061 ttcggcagta ccgatttttg taactttcaa cgttccatca ttaccgactg tatttttagg
    15121 gtagagatgg atagtatcta gttcttctgt cccgtattta taagagccat ctgcttgttt
    15181 gatcatctca tatacaggga aagctaaaac catgtttgcg gcagctgaca ctccgtcttt
    15241 tggttcttct ttgatcgtgt agactgcatc tttcccattt tgttttttag gtaaagataa
    15301 agtgacattt ccatcagcat ctgtcgttcc tgaagcaact ggtgtaccag gagtcaaaga
    15361 ctggactgct tgttttgctg catccacgga cgctccttta tctcgttgcg cataaaattc
    15421 ttgagtgacg ttataaactg aaaatgaaat atcggctaat ccttggtatt gatcgaattc
    15481 gctcatttct ttcccgctgt tttggattaa aggatcgggt aaatcagtca ttttcttttt
    15541 atgaaggatg acttgagctg ctgtctcctc tgcaaacact ttttttgcgc cgaagctgtt
    15601 tgtgagtaat ggtaaaataa ggaaaaggac tcctaacata acgtttattt ttttatgatt
    15661 tttcattttt tcactcctgt tctttttttg ataaacaacc agattgcaaa gcttgcgaat
    15721 accataccaa caacgcctaa aagtgtattt ttcgtttcgt ttgtttttgg aagaaatgga
    15781 cggctatttt cttttttatt gactactttc aatatactgt ccgcctcttt atcctcagaa
    15841 agaaaagttg aaatggtaaa cggaatttct gtttcactta aaatataacc agaaggtgct
    15901 tcgatctctt ttaatcgata acttcctgtt ttcaacccgg aaattgaaaa agcgccattt
    15961 ttatcggaaa tcaggtgaag cgcatctgat tcgttctttg tccacttgta tccgttggct
    16021 gtttgctgga ggtaatttcc tgctttgttt ttaataagga atactgcgcc agctaatcgt
    16081 ttatctggtt tatttgtctc gattttgaca aattgcttac tccctgtata tacagagact
    16141 ttctttgtac tgacaccaaa accaaaatcc agtgttccgt tgttgttgat ttccttgttc
    16201 gcctgtgctg tactgcttag ctgcatctga taagaaatgg tcagtttttt tccagcatat
    16261 ttttccaacg aagggatcga aaataaaaca tcaaatccgt gaggtttctt gtgtatgaca
    16321 aagccttctg tcagcttttc tccattcgat gaaatcgtta aactattagg taaaaacgtt
    16381 aatgcttcat ccgcactatc tgacaattcg aacttttgat agtcaaggat atttacagga
    16441 attgtcgtat gcaaggaata agtgattttt tcaccaatcg taaaatcatt tctaggctct
    16501 tctaatacct tctcaaaagg tggatcaggg tagtcgtttt cttcattttt aggatacaaa
    16561 tggatagttg aaagtttttg attgttttgt ccatgtacag gaagaacaac taccatattc
    16621 tctgcctttt ctttgacgac ttctggtact ttggattcaa tgaaaagata cgctttatct
    16681 cttttttctt gatctttagc ggccagagaa aaagaagcga taccatcttc gttgttaaga
    16741 gttgtagttg ttgcttctgc ggtaaacata ccggaagacg caccgttttt tgcgatctct
    16801 gcttgtgctt cttctaccgt tttgcccttt tcccgtagat ggtaaaaaga atctgtgaca
    16861 tcataaactt ggaatgtgac accatttaat cctcgatacg tttgtaataa agctttttct
    16921 tgtccgtcat ttggatgatt tttcggcagt tgcccgtttg ggaaaagcaa tttgtgtaaa
    16981 gtaatctgaa ccatttctgt ttctgtttct gttgctacct gagtaaaagc tggtttaaat
    17041 agtaacaaga agagacacat actaagccaa ccaagttttt tcatatttag ctgccccctc
    17101 tttctttttt caaaaaaaga taccaaatag aaaacgcaca accaatcatc cctactagat
    17161 agattcctaa acggccaatt cctcccgttt caggtaatgg tacttttgcc tgattcgtga
    17221 tgtctaaaga aatctggttg tttttggctc ctggtgacag aacagattca tgatcttgtc
    17281 catccacttg aattgaccca tcttcgtgta taactatagt aactggctct tttagacctt
    17341 ggtatccttc tggtgtaaaa gtttcggtca gcgtataagt tccaggtttt aaattttcga
    17401 atagaaaggt atctgtttct tgtccatctt ttggcgattc taagtccatt tctggtccct
    17461 gcagtctgaa ttttgctcct tttaatgtct gtccgttgtc ttcttttttg tgtaccgtta
    17521 gatcaaacgc ttttagtcga ttttgatgag tgagcgtcca tacattattt gtcatctcgg
    17581 tattttttcc cgtgtaaatg atttttccat atttatcgat ttggaattca taatttcccg
    17641 gcgaagtatc atatccggca ggaccagctg tttcaacgac tcgatattta ccaggtgtga
    17701 gtgaatcaaa actggcaaga cctttttcat tcgttgtttg gctgtcaatt ggctgataag
    17761 taccatttgc ttcttttttc tgtagggaaa atgctgctcc tttaagattt atctctttgt
    17821 ccgtcccttg catcgcatac ttacgtactg ctacaggaac ttcaacaaaa ggattttcaa
    17881 tagtcaactg gatcgtatca tcggaagtag tgactgtttt tccatcaatg gttaccgtac
    17941 catcagaagc gatcttgatt tcccaagtag tctttttgct taatccatgc ccttctggag
    18001 cttttgtttc tgtcagcgta taggtcattt ctttttgcaa tttgacattt tctggaagag
    18061 aataggttcc gtcgccatga tctgttagta aagtatcaat agaatctcct gttaatttga
    18121 aaacagcgcc aataagatcc ttttcacctg tagaggaatt tttcgttatt ttcaagttta
    18181 acggtgtgaa ttgtttagta tttttccatg tcattgcatc tatttgttga gaatcgtatc
    18241 ctggtacagg taattctttg attgtttggt aactgaatgc ttgaccttga ttattgtatt
    18301 gaggtagtga taatatctct tgataacttt ctccgctatt tgcagataat ttgtcaatgt
    18361 ctgcacgttc ccacgtattt gttgtatctt tagctggttt aatgattcga atatatccgt
    18421 ttttccaagc tgcagcattt gtcgtatgtt cccgttgaat ctcaaaagta acttgatctg
    18481 gacgatcagc tagattgttg tcaaattctt cccataactt tttgatgtga agactgactc
    18541 cgggagcttt agcagatggt ataccgaatt cagctaattc attggtatca atgtttggct
    18601 ggaaagttgt cctgccgttc atttgatacc agaaatttgg atggaagtcc tcattttctg
    18661 tttggattct cacttggtaa tggatttgga tttcttggtc ttttcctaaa tagatctgat
    18721 tgctcttgat ggtatttcct tctatggaaa tagatggagt gaccgttgta ggacttgtcc
    18781 ccacactctt gactgaaagt gtaccaggct gataaatgaa tggttctgcg attggatcat
    18841 ttatttgtcc attgcttaca gttgctgaga tctgtacagc ttttttggct aggtattcag
    18901 agatatctgt tgcatgatca gctgattcat agtaaagatc gcctttttca tctgatgaaa
    18961 ccatttgtcg catacgagac tctacttctg cttttgagag accagctgcc ggatcgcttt
    19021 gaagttggat gccaagacca tgtatttcga ttcctcgttc tttgagtgcc atcgcttctc
    19081 cgatggttgc gataaacgta ctgtcgattc ttctggatag attgttttgg tcaggtgcat
    19141 catagattct tgagattaga gaagtatttc ccggccgatc ttgcgtatta gaaaactgag
    19201 ttccgtaata attgctgctt gattgtgcgt gtacccgctg tactttatag gaaaatgttg
    19261 gtacaccatc cgtcagcaaa acgatcactt ttttatgtcc atttggaacg gatagcatgc
    19321 ttcctgcatc tcttagtgct ttttgtgtaa aagtaccacc atttgtccgt gaaggtgtaa
    19381 tggattttac ttgatttttc actgaatcaa atgaacccat ctgtactgca ccgttactgt
    19441 agctatatcc ttcgcttgag tagccgacat atcccatatt gattttgtct gtgataccgc
    19501 tatctgctaa agtatcgaca aaacgatcga caccaatctt tacttcaccg atccgattat
    19561 tgtcgttcat acttcctgac cagtctacga ccaatacgag atcaagaggc gtgatatctt
    19621 tttgtacatt tccacgagca ttcaaataaa catcaaacaa tccgggtgta cttgtttcct
    19681 ttgcatactt tcgtatcgca tagtctgctt gattaccggt tcctccatat tcgatatacg
    19741 aatgggtccg atcattagga tctccattcc aagaatttat accatcccat tgatttgttc
    19801 cgtttttatt gccttgatga tcaagaacat ttgtatttcc tgtaggttgc caactggctt
    19861 taggataagt gccctgatca tctgttgtat attctgtagg aatcgtttga ttagatggca
    19921 cactcacagc tggcaaggat aatgtaggca atgtaaatgg gctgacagaa ttttcgtttt
    19981 cttttgatga ttcttcttct atttcgtctg gctttggtac tgacacatct gtatctttct
    20041 tattttctgt ctcatcaata atgtcatatt ctttattatc gacgatcagc ttgtttgcct
    20101 ggctgtggta aagtgctgga tcgattggaa aactcagatc gatagtttgt ttagtgtttg
    20161 atgagatttc caacgtaatt ttcccgctat ttacctgata agcatagtca tctccttctt
    20221 ttctttccac atcacttaag taattttcga ctagaccaat ttctttttct atcttttcag
    20281 cactggtgtt attcgcattt agcttgatgt tcagtgcttt ttttccagac tgatccgaaa
    20341 tgacttcagc tgaaattgtt tctaaaactg ttggatcatc tgtagtgtct gctattgcag
    20401 ataatggcac aaagtttgat aaactcaata ttatcagcat gaaaataact ttcagtttct
    20461 tccctgtggt cgtcattttt cccctccttt ttcttttttt ctgttttgac gtgaatagtg
    20521 aaaattatta aaataaacag gcgttacata attttattta ttttaatatg ataattatta
    20581 tacgaagggc gctaaaggga atcacaccaa ttttcatacc aattggtttc atttatgaag
    20641 ttgattcctt cgattaatga gcgtttcatt gaaagaaaag ggttgaggga gaaaaacata
    20701 tgatcaggtt gttggaatta aactatagaa agatggaaaa aatcattcga attctgtcca
    20761 tttctgacaa gtggatgact aaaaaagaac ttgccaaacg aattggtagt tcagaatcta
    20821 catttgtaag gtatatcgaa gagatcaaaa tccgctgggg aacggatgta acgattcaat
    20881 cttcacaaaa attggggtat cgtcttgaac atttgaatgt accagcttat ttaaatgttc
    20941 tgatggaaat gtcgcaaagt tctacaaaca gtcgtttatt aaatgagatt attgtcaatc
    21001 cgggtaaaac gattgagtat tattgtgaaa aaatttccat cagccggtct tcttttacac
    21061 gtaagttgaa acaatgcaat caaattttag aaagctattt attaaaagtg atcgttgacc
    21121 aaggttttca gttaactagc cttaaaagtg agctccagtt gcgtatcttt gttacctttt
    21181 tctttttaag ttactacgga agacgcacgt tgccatttcc aatcgaaaaa aagaagatca
    21241 aagaaattat ggtcaagaat aattgtcaga tgaatttgtt tcaggaagaa agcccatatg
    21301 agcaatcttt ctttattatg tattttgttg tgcatctcat gagagaatcc caaggaactc
    21361 catttgaatg gaaagctgga gactcttatg tacagttgat aaatatcgat aaaaaagact
    21421 tcttaatctt gaaaaatctc ttaggaaaat tgaagtacag cagctatata aaagtagtga
    21481 actattttgt caatacgatt ttttcagaat tttcggagaa agaaaaaaat gaaatcagtg
    21541 agcagatacg aaaaaatatg tcctactgtt cgttttcatc cgctgattgc aaagaaaaaa
    21601 acgaagaata tgttgttcaa ttattaacgc aaatttattt tttctcccgt attttcccat
    21661 acgatacgac tcatttgacg atccgtgcaa cttactttgc acagcagatg caacaccgcc
    21721 agatacgtct atatgctgga tttcgtgcag aacttcaatt ttattccact ctactgaatc
    21781 agaatctgat ttattattta tctagctata tcttttggat gcttatcggt aatcctgaaa
    21841 ttcaccatta tacttctgat aaaaaaatac tgattatcag cgacttaagt cttcgacata
    21901 gtcaatatat tgaagaatat atcagtgata ttcttgctgt gcataaaatt cactctgaga
    21961 caactgctat tactgaagat cagctgtcga aatacaatct tctcgagtat gatctgatcg
    22021 ttacgaatca acccattttg aatgcccatg ttcctcatat attgattgat gatagtgtgt
    22081 cattcgcaaa tgaagaagaa ctcatccgct tattcgagtt atgaataatc aaaaaacagc
    22141 tatgtataaa ccaccctgat aaaaatttca ggacaaatac acatagctgt ttctttttat
    22201 tgtattcctt cagcaatcca acgagattta tagcgaaagt cttttaacaa ctcttctttt
    22261 gtccaattat ttgcaatgag atccgtcaaa gtgttcatta cgagggtcat ggaaaagtat
    22321 aggaaactaa ctgcttcttc cgacgattga atggagaaat gattgattct taataattcc
    22381 agccattttt cgttcattgg agaatcagcc gatagttctc tacgtttggt tgtctgctga
    22441 tcatttcgct gggttaacaa gtataacctt tgccaataga tactttcgtg atctaagtcg
    22501 cagcaccact ctaaatattt ttcgatcccc aaaaagaaat gttgtttgtt ttcgctaatg
    22561 aattttaaga tatcttgatg gactatgtga gaactgcttt tgatcgtata caaataagca
    22621 tcttccaaat cttgaaaata tttataaaaa gcaccgcgcg acatccccat cttgtcaacg
    22681 atttctgaga ctttgacttg gctgatgtgc tgtgagcaaa atatctccag taataggtca
    22741 tcgattctct gtttctttgc gttcgataaa ttgaaaaaag tttcttttgg catccacatc
    22801 tctcctttat ctctgattat acgtggatag cccttcattg tcatgaagga ttcattcctt
    22861 ctttttctct tcttctgtca agtacccatc ttccattcga taaacgcgat cactccattg
    22921 aatcatacgg acatcatgag taaccataat agtcgctttt tgtttctcat gagcttcttt
    22981 aactagtaat ttgacgactt catatgcatg atctgtatcc aaactagctg ttggttcgtc
    23041 tgctaagatc aagcttggct cattatataa agcgcgagca attgccactc tctgtctttc
    23101 tccaccagaa aggtctttag gataactatt tttaagtgac tggatatcta aagattgcag
    23161 caaggaatcg atttttgttg aatcttcttt ttttgaagta acttggtcaa ctagttcaaa
    23221 ttgttccttt accgttaaaa aaggaatcaa attagagctt tggagaataa atcctatttc
    23281 tttaaagcgt aaatctgctc gttttttttc tggaagctca gttagtgagt gaccgttgat
    23341 cactatttct ccggaagtcg gtgtttgcaa tcctcctgaa atggtaagga aagtactttt
    23401 acctgaacca gaaggaccaa tgatgctgac gaattctcct tcctttacat aaaaatcaat
    23461 tgctttcaaa gctgagacct ttgtatgacc agaaccaaat gttttggtaa cttttttcat
    23521 cgttaatatt tttttcattt ttattaacct cctattgctg taattgggtc tactttggtt
    23581 atcgtacgta tcgaaaacaa tccgcctagc attgcgacaa tgatcaaaat cccactatat
    23641 agcaaccatt gtgaccaaaa aacagcaaaa ggcatcgcgc ttggtaaaat cagactagtc
    23701 aaataagcaa acaaaagagc aagcagaacg cctaccaccc caacaataaa ggactgtgct
    23761 actaaagatt tagcgatgaa gaaatttttg atcccttgtg ctttcattac tccaaaaata
    23821 gcagtcttct gaagtgtcat cacgtacatg aaaataccga ccacggcagc aaccactaag
    23881 aacaaaaagt atatcatcgc atttaaggtc atattttggg cagaatagcc aggaatactt
    23941 tcaatgaatg tcccaatagt taataactgt agacccttcg atgctttttc tttcgaaatt
    24001 ttagctgaat cctttattac gatcccattg atcggctgtt cttcttcaga agcaaacggc
    24061 tgttgtccat acttcaaagc agtccacgta tctagggacg catagatgac gggagaaact
    24121 gtgtaataag tttcaggaaa gataccgaca atcgtcaaag gatcgtcgta actgccaatt
    24181 ttgatcgtat ctccaatttt atagcctgaa tcagccagat tttgagagat gatgatttca
    24241 ttctttgttt taaattcatg ccctttcgtg agttttggta ataaaaatgc ttctttcgtt
    24301 gtgccgaaaa ctgtaacatt ttctttgttt tttcctttga ttgctccgct gtacaatccg
    24361 attggtgctt tctctcctcc ttcaatgtat ttcagatctc ctcttgttaa ttgtgaagct
    24421 gcaaatactt gatttgcatc ctccgacaaa acaatctctt gtgcgtccca atcatcgatt
    24481 gcttttttaa actcttctga aagtccattc gctagtcctg acaacatgaa tacgacatac
    24541 gcaatcaaga acataatacc gacgatcaag ccatatcgta atttagaata gcgaatttct
    24601 ttgatagcta gaaacatttg tttttcctcc ctatgataga ttgatagtga caaaatgtca
    24661 cttgttgaat agtgtaactc taaagtgaca atttgtcact tgtgttgttt ttttcttatc
    24721 aataaattgt ctaagacatc tttcgataaa accttaacat gagtcataaa aaatttattt
    24781 aagccttatt tatgctttcc atgataaact aaagtgacca aatcaatgag gtgggaaaat
    24841 gattaaacta ttagtagtag aagacgataa agtattatcc aataatataa aagaaatact
    24901 cgctgcaatc ggcgagataa cacaagttta tgatggtagt gaaggactgt tcgagttgga
    24961 aagtggagtt tatgatcttg caatcttgga tttgatgatg ccggaaatga atggatatga
    25021 agtgttagca aaaatacgga aagaaaaaat acagactcca gtattgattt tgactgcaaa
    25081 agatagtttg gaagataaga ttgaaggatt tgaacgaggt gcagatgatt atctaacaaa
    25141 acctttctat cgagaagaac tgatcatgcg cgtgaaagca ttattgaaac gctcgctagg
    25201 tctctttgat gaaaatgttc tgaagtataa ggatatcagt tgtgatttaa aaagcaatga
    25261 agtcttgtat aaagaacaag ttttgcccat acaaggaaaa gagtttgaat tgctcgttta
    25321 ttttttacaa aataagggaa tcattttgac aaaagagcag atatttgacc ggatctgggg
    25381 atttgattct gatacgacga ttacagttat tgaagtttat atgagcaact tacgaaaaca
    25441 tctgcgaagt actggattgg ataaagaaat caaaacctta cgtaatgtcg gttatatact
    25501 gcaaagggtg tgatgcaatg aatggagata ttacacgaaa gcaacgtagt cgcttttttg
    25561 cgacaaatgt agcagcattt gcttttatct tttttctttt gggattcatt actttacaga
    25621 tattaaacca atctgcatac agagaaacag atctgtcatt agagaaaata aattttgatt
    25681 ctcgaacagt acaattagag atacaaagat atcagcaagg cgatcccttt ttaaacccga
    25741 ctcaaacgga acaaaacaga acaaacatgg aacagccatt aatggaacca tcaaatgacc
    25801 gttttaacac tcaagtgatc ttgtggtcta aaaatggtga gatattgaat aaagcagcta
    25861 ttggtgggcg tttcaaccaa atcaaagaat taaaaatgga tacgaaaaat ctgaatacca
    25921 tccaaaatat tgaattaaat gaagacagtg gctcatctgc cctctctttc cgttcgatta
    25981 cgaaaaaagc ggagacgaat caagatggcg ttgcctacat ccaaatttta gaaaatacaa
    26041 atcaaatcaa gaattcatta gcgacttttc gcacgattat gattttgtgt atgattgttt
    26101 tttggattct ctctattggt atcagttatt acttgtctag tctaagcatg cgccctatta
    26161 ttctttcttg gagaagacaa aaagaatttg ttgagaatgc ttctcatgaa ttgcgcacac
    26221 cgttaacgat tattcaaaat agtttggaac atctttttac caagcctaat catactatta
    26281 ttgaagaatc cgaaagcatc gctcaagcat tgtcagagac gaggcgcctc actggattga
    26341 cttcggattt gctgacaatc gctcggaatg attctgatca gcagctgctt tcaaagcaaa
    26401 tgatcaatac acaagaatat atcgaacaac ttgttaaacc atttcaagag atggccatca
    26461 tagatggaaa agagtttatt ctccataacg atgcaacatt agaagtacca attgatgaaa
    26521 aaaaaatcca tcaagttttg gttattttgc tggataatgc attaaaatat acgaatccag
    26581 aagataagat cattttggat tcatctgtta accataaaga atggctgatt cacgtaaaga
    26641 atactggccc ttctatcagt gaagaagatc aagcaaggat ttttgatcga ttttatcggg
    26701 aagatcaatc tcgggcgaaa gagactggcg gatacgggct tggcttggca attgcaaaac
    26761 aggtaatcga acagcatcat ggacagattt ctgtatccaa ttatcttcca caaggagtcg
    26821 attttaaagt ccaattgccg ttgaagccta aaaaataatg cttatcccta aaaaagggct
    26881 gtgacaaaaa tcttgtcaca gccctttttt gttgcgaata aacggtgttc cagaagtagc
    26941 ttcttcggaa ataagccgaa atttctttaa gctgaccact tctgtcacaa cctctttagc
    27001 ttacgcttac gattttttat tgcggtcttc aatgtgtaca tcaccgcttg tgtcaatatc
    27061 caattcttct cggctaacat cttctgtcac tttttcaaca tcttcatgtt cttctttatg
    27121 aatcccaact tcttcacgaa taactgtatg tttgcttaca tctacttgct cttctttgat
    27181 tgggatagta atcgtgtcat cttccaattt ttcgtctgtt ccctgtgaag attgatctgt
    27241 tactggtttg cgttcgatga cgatttcttc acgtttgacc ggtacttcta ccgtttcagt
    27301 atcgttgacc acatgtttgt ggatgtcgac ttctccagtt gtcacatcat gtgtatttac
    27361 atctaatttt tcttctttta gttgaattgt atcatcatct agatttggtt tgcgatcgat
    27421 gtcttcagtc ttgcttgtac ccattgtatc agtctcgcca ggtacgtcca tcggatcagt
    27481 tcctggtgtc atattcaatg gatccgttgt attttgaaag cctgtcgtgc cacctacgtc
    27541 cattggatct gttccagtgc cagtttctaa tccagtcccc attgtgcttg ctgggctaac
    27601 agtatcttgt gtatccattg tatcttctgt tgtttctggc tgacgatagc cttttactgt
    27661 gatgacaaat tttccatcag aaatatctcc tctatattga tataaaggat cattttctgg
    27721 tgtagccgtc tcagaatcat aggtatcaaa agaaaaagta tcttttattt tttcccataa
    27781 agaacggtct tcttcaccat ccatccgatt ttcatctgtt tcaacatcta taccagacaa
    27841 tccgtcaaat cctagtctag atgctgcttc atcagtagta taaataacga tatcatctcg
    27901 ttcataccct tcgttacgca accgttcaat tactgataat gcttcttccc tcgtactata
    27961 gcttccgatg accgttaaat ttttctcttc catgtaaatt cctcctagca aatagattta
    28021 tgattggtat attgttactt ataaatttat tctataggag acgattgttt tctacaaata
    28081 tttagattgg aatttgatta aaacaattta attgaaattt gaaaacattt atgttaatga
    28141 aagtcatatt ctaataaaat gtcatttgtt tctatatgaa tttttatgaa aaatttcata
    28201 taatttccac tcgttgtgat ggtttaattt atccaatcca tcaataagca aacaacttat
    28261 ataaaaaagg attaattctc aatataattg ctcctaccat agaataaatc ttcatgtaaa
    28321 gtaatgaagt accaactatt tctaatactt ctttaagaat tatcccaaca atatcgttag
    28381 acaaaccatt attgaataaa tggagagcca atcgattctg aaaaaatgtt ttctaatttt
    28441 tcggaaataa aagaaagagc ctcctgccat tagaacgaac caaatccatt tcattgctca
    28501 tgaagtaacc acatagctaa aaagaggata aatcaattaa aagatcaaaa gaatgactgc
    28561 actaataaaa taactaaaaa tgtatcttct tacttcatat cttttagcta gtacttagtt
    28621 aaaaatttgc ttcctaagat caagacaaac tgtctatctt catttgatga aatgcggtaa
    28681 aatatagaaa atgaacacta ttggagggaa tttgtaatgg acagcaaaac tagaaaacaa
    28741 ctgcaagaaa agttaaagca acgtacacac ttgctccctt ccgtctttca acagttttta
    28801 gaagaaaatc gttcttccct ttcattaggc agtcgctatg aatacgcaaa agattttcat
    28861 ctgtttactg attatttgag aaaagtattt tctgaagaag tggatgatca gctgattatc
    28921 catttagaaa aacaagatta tcagaatttc ttagctaaaa tctatcgaca tactcgttcg
    28981 ttccaaacta cagcgaacca agaaacggag caattgtttg aaaatagcta ttacgggatt
    29041 tcaaggaagc aatattcatt aaatcatttt ttacgatttt tgtatcaaaa aggactgatt
    29101 gaagaagaga tttctctttt gggtacaagt ttaccggaaa caaccaaagc agctccgcga
    29161 tatatcgatg cagaactttt caaagatttt gagcatttgt ttatcccgat tgaaggcttt
    29221 caaacaagca gagaagctag ctttgaagaa aagaatagac cgaggaacct tgcaattact
    29281 gccattcttc tgtattgcgg attaaagatc catgaagtag tagaacttaa acgtaaagat
    29341 gtatctttga ccaagcagat tcttaatctg aatagaaaag aaaacagact gaataaagta
    29401 ccaataccaa aagaagcgat gccatttctg gagaactatt ttaagttaac agcacaaaat
    29461 acggacgaaa attcttttgt ttttcgttcc tcacatgatc agcaaatttc tcctcggact
    29521 attcgccaaa ttttgagcaa aattacagta tataaaaacg tatcgccaga actatgcaga
    29581 aaaacatatc gttattatgc agaactatat ttagatgatg ctgacgcggt aaattattta
    29641 tgtggtaatc gatacctctc atcccattct tttcaagata tctgggaaaa gatggttgat
    29701 ttttcttatc acgaattagc ggcattcgtt cgggtttctt ccatataaaa caaatgtatg
    29761 atcttttttt cacaataaac tatgttatta tataaaggat tatgttacga ttatcttgaa
    29821 tttgtatatt acttaacaaa agataatgga gtgtgaatga tggagaccat aacgtattcc
    29881 cctttgaact tatttacgaa ttttcaagaa gctgcagcta acttttccga gaccccgatt
    29941 atctttgatg agccactttc agctttccca gaattaggac ttgaaacaac ttacaaaaaa
    30001 tgctgcgaaa gtgtgttgaa acgggcttat caattggctc atcttggagt gaaatccgga
    30061 gacaaagtta ttatttataa gagttccgct tttgacacat accttctagc tgtttctgtg
    30121 tcttaccttg gtgcagtgcc tgtcatgact tcttatcatc taccaacaac aacaatggaa
    30181 gtatttatcg atcgtttaga agaccctttc attttatttg atgatgagac aaaaaagcga
    30241 gtgagagaaa tttcaaatgg aacaaaatca aaacagattc ctattcttta tttaatggaa
    30301 caacctgctt tgtctgtttc tcaatcattt ttagacaaaa atgaaatttc ttatatgacc
    30361 catacttctg gtacaactgg tatccctaaa cttatttgtc attctgctca ttctatggga
    30421 tggcggacga aatggcaaaa aacagttttc acaaaaattt cggaaaagaa attaatcgct
    30481 tttcacatct ctccagtgca ttccagattc aatattggta tctcttcttt gatgtccatg
    30541 ggatttccta tgatgccttt agcaaacgca caaagttcaa aagttgttca tatgttggaa
    30601 gctcaccggc caattgcact agagacccat ccgaataact ttgttcagtg gcgttttact
    30661 gctaaggagc atccagaagc tttttcgggt atccgatact atcactccac ttttgatgct
    30721 ataaacaacc agacaatgaa gacatttttg cgaacgtcga tggcacagga tgcggtattt
    30781 cttcaagtat atggccaaag tgaatgcgga ccaatgattc ttaaggctca tacactagag
    30841 agtttgaaaa caagtgatgc aagagatatg ggcgttggac tggaagacat gacaagcgct
    30901 cggattacag attcagttgg gaatgtccta cctgaaaaca cagatggtca tatacaatta
    30961 ctgtctaaag gacgggcttt gacttattac aaggaagatg cacggttcca ggaaaatgtt
    31021 tatggcgatt ggtgggatag cggagattac ggttttatgg ataagcatgg ccacctattt
    31081 ttgaaagatc ggcaagtgga tttgatcgaa acgatcaata gtacattagc tattgaagac
    31141 tttttattag attcgttaga ttttttggca gaagtagtga ttgtaaggga taaaaatcat
    31201 tctccacaac cgattattgc tttagctcct gataaagaaa tggattggaa tcgatggtgg
    31261 gagcaagtcc atgaacttcc tcgcttgaac gtccctatca tccgtgattt tgatgcaatc
    31321 ccgcgaacag ctacaatgaa agtgcaacgg cttcaaatcg agaaagaatt aaaatcacaa
    31381 aagtcctaac tatttaagga aagaaagatc cattttggtc tttcttttct ttttgttttt
    31441 ttaaattgga tgagataaaa atatgccaat tggctgtttt tcttttttga aaatttcgtt
    31501 atactcttat tcatggagga aaatgttatg aaaagaatct tgacaattgg cggttctgat
    31561 ccatttgctg gtggaggaat ccaaacagat ttaaaaactt ttgagaattt tggtctattc
    31621 ggactaagcg ccttgacttc tataggggca ctagatatta atgagcgatt tatgctggaa
    31681 tctatatctt tggaattgct taaacgacag ttagtttcga ttgataaaat gacttcatta
    31741 gatggtatca aaattgggtt attgaattca agtgaagcaa tcatggttgt tcgagacttc
    31801 ataaaaacaa aacaaaatat cccaatcatt ttagaccctg ttttggcatt caaagaaact
    31861 gaagctgtga tcaatcaatt gtatatttcg cagctcatcg aagaactttt tccacttgtt
    31921 acgatgatta cgcctaattt ggcagaagct gctttacttt ctggtcaagc tcttccctct
    31981 tcgttaacag aaatgatcca tctcgctaaa gaactcactg cttcaggaac aaaaaacatt
    32041 gtgatcaaag gcggcacaag gatggctgga gatgaagctg tggatcttct ctattcaatt
    32101 gatcattatg aggtattttc tcataaaaaa atcgacacta caacagtaaa cggggccggt
    32161 tgtgcctttt cttctgcaat aacagcgaat cttgtgttag gggcagattt taccaaagca
    32221 gtagcagaaa gtaaaaaatt tgttgcccat tgtatttcta atggcgtgct gatgaacgat
    32281 cataccggaa gtgtctggtc tggcggtatt caaaaaggag gaatgagaaa tgaaaactaa
    32341 gcaattaacg atctatgcta tgctgattgc gttgacagtt gccctttcat taacaatttt
    32401 gatccctgta ccggctacga atggatttgt gacattatgc gaggccggga tctataccgc
    32461 tgcttttctt tatggtccaa cgggtggatt agttgttggt gcttccagtg gtctattgat
    32521 cgatttgatt tcaggatatc cgcagtgggc agttttttca ttagtgatcc acgggttaca
    32581 aggatatgtt gctggttctt tcagcaaatc ttctactcgt atgtggggat tagggctttt
    32641 attaggaagc ttagttatga tcatcggcta tggtatcgcc ggttggattt tatatgattg
    32701 gccggctgga gtggcttcta taccaggaaa catcttccaa aatctgattg gaatgggact
    32761 tgcctttcct ataactgcaa gtcttcaacg tattcaagca cggaagcaat attaattgaa
    32821 aaagaaggtt ttagaaaatg aagttgtcag aaaaagaatt aaaagaccaa ttgactgaaa
    32881 tagttaatga catattggct gaggcacact tgaaaaaagg tgatcttttt gttttaggat
    32941 gcagcacaag cgaagtcgtt ggaggacata ttggaaaaaa ttccagtgcg gaagttggtc
    33001 aatggatcat ccgtacgtta aaagagttgt tggatcctaa agaaattgcg ctagctgtcc
    33061 aaggttgtga acatttgaac cgagcattag tagtagaacg aacagtggca gaagcaaaaa
    33121 atttcgaaat tgtctctgtt gttcctgcac tacatgctgg aggtgcttgt tctgttgctg
    33181 cttttgacca gttcaatgat cctgtcgaag tggaacacgt agttggacaa gccggtatcg
    33241 atatcggtga cacatcaatc ggtatgcata tcaagcatgt ccaagtacct gtcagacctc
    33301 gtttgaaaac ccttggacaa gctcacgtga cagcccttcg ctctcgtcct aaatatatcg
    33361 gtggtcctag agcgaattat tgaaatgagt aattgacaga gcaatctgaa aaacttcctc
    33421 gcaaagtcca actaatgaac tttaacgagg aagttttact tgtttgtttt atataaccga
    33481 gcttcataag gtgctagtat gcctttagct tcaaattctc cgctagagga atttgacaag
    33541 agtaatgtcc aggactgatc tgcttctttt ggaagttcat agtcagcaag tgattctgtt
    33601 aagtttacca taataagata ttgttcatct tctaaatatc tttcatagac ataaagttgt
    33661 ggatgttcat gaagatattc tttataagaa ccgtatatca gacctttatt ggtttgtcta
    33721 atgcggatca tgttcttata gaattgcagg accgactctg gttcatattc ttgttgttct
    33781 acattgatcg ttttggtatt tggattagtg atcagccaag gttcatgtgt agaaaaacca
    33841 gcatattgtt ccgaagtcca ttgcatgggt gtcctgctgt tgtctctcgt tgtttcacga
    33901 atgatatcca atgcttcttc tcttgtctta ccttccgcaa gcagcctttt ataaagtctt
    33961 ttcgaatcta ctgcatcaac ttgatcgatc gattcaaagg gcatattcgt cattccgatt
    34021 tcctgtcctt gataaataaa tggcgtacct tgcaaaaaga aatacatcat agcgattgct
    34081 tttgcagaca tagcccaaaa atcgggacga gtatctccaa acactgaaac ggcacgagga
    34141 acatcatggt tttccatata taaagcgttc catccgatac catccaatga agtttgccaa
    34201 gcgcttaatg catgtttcaa tttaaggaca tctaattgcc cttctttttc ttgctgccag
    34261 atatggatat gatcaaattc gaatatcata tcgaaataac cgtctttccc tacccattgt
    34321 ggtccttctt ctgcagtgac accacttgct tctccgacag tcatgatatc gtactcttca
    34381 aaaacatgtt tcaaatcggt caaatgttct tcgattcctg agacattttg aaagggtgag
    34441 aaagggttct ctgtggcttt tactgaatat tcatcttttt ttacatgaga aatcgcatct
    34501 aaacgaaatc catctatccc tttatccaac caccatcgga tcatattgaa tagttcttct
    34561 ttcaatttct cgctttccca atttaagtct ggttgttctt ttgcaaaaac atgcagataa
    34621 tactgtccag tttcatgaga atactcccaa gcagaaccgc cgaaaatcga tgtccaatta
    34681 ttcggttctt tgccatctac cccgtcgacc caaatgtaat aatcgcgata cgggctttct
    34741 ttagattttt tcgattcttc aaaccattga tgctgatccg aactatggtt gatgacaaga
    34801 tccataatca ctttgatccc taattcatgt gcttctttta gcaataaatc aaaatcttcc
    34861 atcgttccga atctctcttc tatatcttga tagtcactta cgtcataacc attatcgaca
    34921 aatggagatt gatagatcgg attgatccag ataaagccga taccaagatc tttcaaataa
    34981 ttaagttttt cacggatccc attgatgtct ccttgaccat cgccattgct atctttgaaa
    35041 ctagcaggat agatttgata gcctactgct tctttccacc atttttgttc ttgtatcata
    35101 tcgtttcact cctttaacgg tccctcttga ttataaccga ttctatttta gaagtatcct
    35161 tgttaccggt aactagaaac gaaaagctca acgaatctgc taagtgcgtt cgttgagctt
    35221 tattttatca tagatagcgg gcaatcagtt gaatcatttg cttgggaaat tcattcaagt
    35281 cagtaatatc tacaaaacga ctttcaccgt agatcgactt gatttcttct ttgtcttggc
    35341 caatagctgc ggagacaaat aggattcctt gacgttcata ttctttcaaa acagactgga
    35401 tatcttcttt tgcttttttg cctgtataat ccggcaacgc ttttggctga ccgtcactaa
    35461 tattaagcaa cagtttggtt gttgcggatt gtctgtttaa tttttctgct gctaaacgaa
    35521 gtgcagcacc atcacgattg ttttgccttg gtttcatagt gactaatttt tcatttaacc
    35581 attgaaatcc gtcttcaaat tctttataag aaaacaaaga agtcttttct cttgacgaac
    35641 ggtctgctgt atctccgtaa atcaacaatg ggatatcgac tttcttagaa aattcggcaa
    35701 tggcaatcgc tgcttttttt gccgcttcga tccgatcatc ccgtatcatt gacccagatt
    35761 catcgatccg tacagctacc gctaaagaag gttgctcatg tggcgggttc tttttgtcaa
    35821 aatttctcaa atcaccatat gctactttgc ttgcattgaa ccgctgacct tcgtattttc
    35881 ctttttggta cgtctctgtt tgttcattat ccagtaactc taaaatttgc cggctaagtg
    35941 attctactat tggcattact tgcatgtgta gctcacgtgc ttccggcgtt tttccttgga
    36001 aagctggtcg gtgaacgatg agaccttctt tttcatgaat cgtttccttc atgatttgtc
    36061 gcgcttcttt attcagttgc ttcttgattt ccttatcatg tgcttccatg tcagaagcag
    36121 acatttcttg agaatcatct cctgtttgtt gttctttttg attttttcct tcgatatcgc
    36181 tactgcgttc tttttgcatt tgaggaggaa tctcgttttt ttctattgtt tcttcttgtt
    36241 tctcttctcc ctcatttggt tcttcagcag acaacgattt cttttcatct aagcgcagaa
    36301 tttcttcagc attttcagtg atgtttcgtt catttgcttc ttcggcgcta atggttcttt
    36361 cttttgtatg ctcagattga ggatgacccc atttttcttt tctcaatatg tcctgaagtt
    36421 ccagtagcaa tccactgtca gacaaagctt gttcaagaat tgccaattca tctgaatcag
    36481 tggataattt atacaaaact tttggataaa tcgactggag taaatcttgt ccttgcttat
    36541 aggtatttgc ccaataaaaa taagaacgca ttcctgctac acctttgatg gcgttagctt
    36601 ttgcagtttc atccaacaaa cggataatct ctgccatctt taagagaagt tcttgttttt
    36661 ggatcatagt tttcgccatc gcacgttctg ccatgacttc taaggcagga agatccattt
    36721 tttccgcatg ttgcatccga tctcttaaag attcatttaa tgggcgattt ccttggtaat
    36781 ttcgatttgt agtgatcaca atgacgcaat ctggatggcg acgaatgatt cctgtcggta
    36841 aattcaacat cccatttggt tcgagcgctg agttaagtgc cacaagaaca gaggcatctc
    36901 ggatgacagt cggctcttga atctctaata aatagccttt ttcaatcgct cgaacgattt
    36961 cagaagggta atagctgtaa tggattgcat ctggataatc agcttcgatc ctttgaacta
    37021 gctctgctaa tttttcttta gcagaaaaag gatcaatgcc gtaatggttc tggatcagtg
    37081 tcagtacagc ttcaagtgta tctgtttggt aaatagcttc tagtaattct tggtcttgtt
    37141 ccttattaga atctactaca ggtaataagg ctccgaaaac atctgatttg tccatatctg
    37201 caaaacaggt cacttttgta tagggaagtt gcagatcagc agatagtgct ttggctaatt
    37261 gtgtcttccc cgacccggca tctccttcca aaagtacgtt actgattttc atttcaggat
    37321 cttgccaatt ccctttgatt tcggaggcga tccgccattc ttctgcactt gtccgatggc
    37381 ttttcggttt cttccagatc atttgctttt ctagccgtga aaaggttcgg ttttctgtta
    37441 gtgagaaatt ctccatgctt ctcttcccct tttgatcatc tctgtctatt aatatcctag
    37501 ctcatctaaa agacgtttta aaatacggaa tcgttcccca atcagttctc cgtctttttg
    37561 tagtgtatcg taatacaaaa tgatgtcttc atcgatcttt ggatttttgg tatctacttc
    37621 taccgtcatt cggttccctt gtaatccaat gatgtctacg actggatttt ctggatcata
    37681 aaatttttca taacgataag catcttggaa gtataaactt ccttgcgcag ctaagatcgc
    37741 taaatctaaa atacgtgtga ttggtaattc ttccgactgt cgtgaccatt tttctccagt
    37801 atgtcgccat accttgcctg agatatcgac ttttccacga tcattccact gagcaaggcc
    37861 cagtgaaagc ccttttgcat ccatatttaa tgcatttctt ccatcaactt tatcatagtc
    37921 ttctacaacg attactggtt tatgttttaa atttgttggt atttccatta ttttaactcc
    37981 tcatcctttt atttttagta aataagtaaa ttagtagttt actcatttac taaactatat
    38041 gcgacattat agaggattga agtgaggatt gcaaagaaaa agagcttcat tgatagaaat
    38101 aaaaacacca tctcgttctt ttacacgctc attagtaaca tgtagaaagt ccaagatgat
    38161 gttggaatat tttggctcta tactttttga tgttggtgaa cttcaccaac atcttttttg
    38221 t
//
LOCUS       DBGZHO010000021        37476 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.021, whole genome shotgun sequence.
ACCESSION   DBGZHO010000021 DBGZHO010000000
VERSION     DBGZHO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.021"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            100..543
                     /locus_tag="ACN3HL_001254"
     CDS             100..543
                     /locus_tag="ACN3HL_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HHC8006144.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(549..1733)
                     /locus_tag="ACN3HL_001255"
     CDS             complement(549..1733)
                     /locus_tag="ACN3HL_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HHC8006145.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2001..2699
                     /locus_tag="ACN3HL_001256"
     CDS             2001..2699
                     /locus_tag="ACN3HL_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHC8006146.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2706..3383
                     /gene="nth"
                     /locus_tag="ACN3HL_001257"
     CDS             2706..3383
                     /gene="nth"
                     /locus_tag="ACN3HL_001257"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HHC8006147.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3509..4042)
                     /locus_tag="ACN3HL_001258"
     CDS             complement(3509..4042)
                     /locus_tag="ACN3HL_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006148.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4339..6720)
                     /locus_tag="ACN3HL_001259"
     CDS             complement(4339..6720)
                     /locus_tag="ACN3HL_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HHC8006149.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6710..7357)
                     /gene="recU"
                     /locus_tag="ACN3HL_001260"
     CDS             complement(6710..7357)
                     /gene="recU"
                     /locus_tag="ACN3HL_001260"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HHC8006150.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7421..7960
                     /locus_tag="ACN3HL_001261"
     CDS             7421..7960
                     /locus_tag="ACN3HL_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HHC8006151.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8050..8469
                     /gene="gpsB"
                     /locus_tag="ACN3HL_001262"
     CDS             8050..8469
                     /gene="gpsB"
                     /locus_tag="ACN3HL_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HHC8006152.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8491..8858
                     /gene="rnpB"
                     /locus_tag="ACN3HL_001263"
     ncRNA           8491..8858
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACN3HL_001263"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9067..10233
                     /locus_tag="ACN3HL_001264"
     CDS             9067..10233
                     /locus_tag="ACN3HL_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HHC8006153.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10279..11775
                     /locus_tag="ACN3HL_001265"
     CDS             10279..11775
                     /locus_tag="ACN3HL_001265"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HHC8006154.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11856..12539
                     /locus_tag="ACN3HL_001266"
     CDS             11856..12539
                     /locus_tag="ACN3HL_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHC8006155.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13184..14374
                     /locus_tag="ACN3HL_001267"
     CDS             13184..14374
                     /locus_tag="ACN3HL_001267"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HHC8006156.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14476..15429
                     /locus_tag="ACN3HL_001268"
     CDS             14476..15429
                     /locus_tag="ACN3HL_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HHC8006157.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15498..16847
                     /locus_tag="ACN3HL_001269"
     CDS             15498..16847
                     /locus_tag="ACN3HL_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHC8006158.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17030..17353)
                     /locus_tag="ACN3HL_001270"
     CDS             complement(17030..17353)
                     /locus_tag="ACN3HL_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006159.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17482..18645
                     /locus_tag="ACN3HL_001271"
     CDS             17482..18645
                     /locus_tag="ACN3HL_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHC8006160.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18715..20064
                     /locus_tag="ACN3HL_001272"
     CDS             18715..20064
                     /locus_tag="ACN3HL_001272"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHC8006161.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20109..20540)
                     /locus_tag="ACN3HL_001273"
     CDS             complement(20109..20540)
                     /locus_tag="ACN3HL_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006162.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20928..23570
                     /gene="alaS"
                     /locus_tag="ACN3HL_001274"
     CDS             20928..23570
                     /gene="alaS"
                     /locus_tag="ACN3HL_001274"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HHC8006163.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23770..24366
                     /locus_tag="ACN3HL_001275"
     CDS             23770..24366
                     /locus_tag="ACN3HL_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHC8006164.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIVTIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24488..25636
                     /locus_tag="ACN3HL_001276"
     CDS             24488..25636
                     /locus_tag="ACN3HL_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHC8006165.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25674..26087)
                     /locus_tag="ACN3HL_001277"
     CDS             complement(25674..26087)
                     /locus_tag="ACN3HL_001277"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HHC8006166.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26166..26597
                     /locus_tag="ACN3HL_001278"
     CDS             26166..26597
                     /locus_tag="ACN3HL_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HHC8006167.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26696..26929)
                     /locus_tag="ACN3HL_001279"
     CDS             complement(26696..26929)
                     /locus_tag="ACN3HL_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8006168.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27112..28782
                     /locus_tag="ACN3HL_001280"
     CDS             27112..28782
                     /locus_tag="ACN3HL_001280"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HHC8006169.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28929..29315
                     /locus_tag="ACN3HL_001281"
     CDS             28929..29315
                     /locus_tag="ACN3HL_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006170.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29302..30000
                     /locus_tag="ACN3HL_001282"
     CDS             29302..30000
                     /locus_tag="ACN3HL_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HHC8006171.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30005..30469
                     /gene="lspA"
                     /locus_tag="ACN3HL_001283"
     CDS             30005..30469
                     /gene="lspA"
                     /locus_tag="ACN3HL_001283"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HHC8006172.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30466..31377
                     /locus_tag="ACN3HL_001284"
     CDS             30466..31377
                     /locus_tag="ACN3HL_001284"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHC8006173.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31612..32151
                     /gene="pyrR"
                     /locus_tag="ACN3HL_001285"
     CDS             31612..32151
                     /gene="pyrR"
                     /locus_tag="ACN3HL_001285"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HHC8006174.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32165..33448
                     /locus_tag="ACN3HL_001286"
     CDS             32165..33448
                     /locus_tag="ACN3HL_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HHC8006175.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33461..34387
                     /locus_tag="ACN3HL_001287"
     CDS             33461..34387
                     /locus_tag="ACN3HL_001287"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HHC8006176.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34406..35686
                     /locus_tag="ACN3HL_001288"
     CDS             34406..35686
                     /locus_tag="ACN3HL_001288"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HHC8006177.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35691..36767
                     /locus_tag="ACN3HL_001289"
     CDS             35691..36767
                     /locus_tag="ACN3HL_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HHC8006178.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36772..>37476
                     /locus_tag="ACN3HL_001290"
     CDS             36772..>37476
                     /locus_tag="ACN3HL_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HHC8006179.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNME"
BASE COUNT        12314 a         6546 c         7979 g        10637 t
ORIGIN      
        1 ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt gaataggaaa
       61 caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag acaactgcta
      121 atagaagaat atctggattt agctaatgag attattcatc gtaataaacc agaaatggaa
      181 aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat cgggaaaatc
      241 cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg agccatcagt
      301 aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag cgaagagaat
      361 aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa tagacacgag
      421 caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat gtcaaaagaa
      481 gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg aagtagcaaa
      541 tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa aaatccgaat
      601 accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg gccgatgacg
      661 cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg gttatctgag
      721 acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc gaaaccataa
      781 cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa tgtgatgaat
      841 agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc tgaaaatttt
      901 ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc aatcaaagag
      961 aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa ttgagaaaag
     1021 atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa taaaggaata
     1081 acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg ggagaaactt
     1141 aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta gccataaacg
     1201 gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc caactcagct
     1261 aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc acccatccat
     1321 ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc atataaggtg
     1381 gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat ccatatcgaa
     1441 tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat aataaggatc
     1501 ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa gaaggcagct
     1561 agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat ggagtgagaa
     1621 taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa tccagtgaat
     1681 aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta catgtaaaaa
     1741 ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat tttgtttcct
     1801 tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa aagtgaagat
     1861 acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat ctgaccgatc
     1921 agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta cgtatactgt
     1981 gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct ggacaaacag
     2041 tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct gaagaatttt
     2101 tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct gatttgcaga
     2161 tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg gatcgtctcg
     2221 taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa gcagatcgat
     2281 ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa gaaaaaaaat
     2341 acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt gaacaagaat
     2401 ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta gaagaagacc
     2461 attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat caggcttata
     2521 gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta cgtacaaaac
     2581 aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga gaagtagaac
     2641 agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg gaggagtagc
     2701 ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat ggaatgtttc
     2761 ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt gcagtgatct
     2821 taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg tttgcctctt
     2881 ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt aaaataaaaa
     2941 cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag cagctgattg
     3001 aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt cctggtgtag
     3061 gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca atcgcagtag
     3121 atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat gctacggtca
     3181 tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta aagacacatc
     3241 atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag tgcgaggtat
     3301 gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa gaaaaggcgc
     3361 taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat gtatgaatta
     3421 tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa agtaaatgta
     3481 catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa taaaagttgt
     3541 tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata cctataaaat
     3601 aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa ggtgtaataa
     3661 aaatgataag tgataataaa aaaataccat ttataactaa acataaacta atggatttgg
     3721 gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat aaaaaagtga
     3781 gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg cttaaaagta
     3841 cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt aataataaac
     3901 aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat aaaaaaagat
     3961 ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg aagccttctt
     4021 tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca atgggattat
     4081 taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt ataaacaagt
     4141 aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt ttaagctaaa
     4201 tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa tacagcttgg
     4261 tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac cacgcttgta
     4321 gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg atggtgtatg
     4381 gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag gaggagcaga
     4441 tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg aagacgctgg
     4501 ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt cgctttgact
     4561 agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag tctggacata
     4621 gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg tatattgatc
     4681 tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc agtctgtatt
     4741 tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg ctacgtgtga
     4801 cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg aaatcgaata
     4861 atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa taccaagttt
     4921 tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat ataacccagc
     4981 gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt ctgtgatcat
     5041 ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt cttctgttcc
     5101 gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc cattggcgaa
     5161 agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc catcttgttc
     5221 ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga tcccaagatt
     5281 ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga ctgctggaac
     5341 attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt gattatccca
     5401 gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa tagtttttcc
     5461 agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt tcatcgtaga
     5521 accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt cttctgcgat
     5581 gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa gggtggaggc
     5641 aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga tatcatatag
     5701 tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg tgtagacatt
     5761 cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat cgacgatctt
     5821 agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta cattaacagc
     5881 ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca aaacagtatc
     5941 tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag gggcttgagg
     6001 catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct taccaaagta
     6061 catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt tatttacgta
     6121 gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca tccacgcttc
     6181 ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg aaagtttgat
     6241 caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt tagagagggc
     6301 agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc gatcttctac
     6361 cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt tttcacgctt
     6421 ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg aagatacggt
     6481 agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc agaaaagtcc
     6541 tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga tcttgataaa
     6601 taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat tcttcttcac
     6661 actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt catttgccat
     6721 tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg tccaaataag
     6781 gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc aaagataaag
     6841 gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa tgaacactat
     6901 tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag accccatttt
     6961 gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta aagggaaaag
     7021 atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga tagacgccat
     7081 tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca gcacttctct
     7141 taggatagtc tactttcacg atttggatag gggtaggctt tttatggata accgccaacc
     7201 cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc atcccccgat
     7261 tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga gaggcattct
     7321 tataataagg ttggccattt ggatagcgca ataccatctt taatcacact cctaggccac
     7381 attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt caaaagtaat
     7441 ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg atcctaaaat
     7501 ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag aagggctgga
     7561 atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa tagtagcgga
     7621 attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt ctgattttgg
     7681 taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat tagcagatta
     7741 tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga atcacactcg
     7801 ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat tccctggaaa
     7861 aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct acgaaattcg
     7921 gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt gtttgattta
     7981 tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat gaaaactaga
     8041 ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca agaattcaaa
     8101 acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa tatcatcaaa
     8161 gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga tcgattgagt
     8221 gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt gcaacaaaca
     8281 gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt gtcaaatctt
     8341 gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa accagcacaa
     8401 cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga aaaaacacgt
     8461 caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc tgacttgatc
     8521 aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg tgcttagcga
     8581 aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag gcttcggcta
     8641 tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc catccggtgg
     8701 aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt tttgtctgga
     8761 agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct ttgttttttc
     8821 tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat cagggaatta
     8881 ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag ctatttttca
     8941 atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg ttattcggaa
     9001 tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata aataaggaga
     9061 ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag cgggctagaa
     9121 gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga gaacggacgt
     9181 gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt acgtacagca
     9241 gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga attgtttgaa
     9301 aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt tcctgtagct
     9361 ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat cacaaaaaaa
     9421 gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc actgacggaa
     9481 actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat ggtaactctg
     9541 gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg tggagcacca
     9601 ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa agaccgtcca
     9661 ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt aataggccat
     9721 aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg gttcagtcaa
     9781 gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga tattgaatta
     9841 gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc caatgcagaa
     9901 gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga cttcaaaacg
     9961 gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct aggagaagaa
    10021 gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt aaaaacatgg
    10081 agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca aaaagcaacc
    10141 aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta ttggggaact
    10201 cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca ttcaattgga
    10261 tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa agaaatcaat
    10321 cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat gcctgaaaaa
    10381 gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt ttcaaaaaaa
    10441 atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga agaattgtcg
    10501 gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga acatcgcgta
    10561 ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg acaatggcaa
    10621 aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca aaatattgaa
    10681 ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta tgatgttttg
    10741 ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt tgatcagctt
    10801 aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga acctgaaaca
    10861 gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt gaaagtaatc
    10921 gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca cccatttatg
    10981 actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac agatttcaaa
    11041 atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca agacatcgat
    11101 gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca tgaatcacaa
    11161 tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa gcaatatcct
    11221 ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa attttatcgt
    11281 ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt gacttaccct
    11341 ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg ggtagatgtt
    11401 gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat acgaccaaca
    11461 aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt tggttatttt
    11521 ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt gcagcaagaa
    11581 atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa ctggatgtca
    11641 gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat ggatgcaaca
    11701 catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta ttttaatgta
    11761 tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa tctatagatg
    11821 ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa gtgatcgctg
    11881 attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat cataccaaaa
    11941 gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac cgctttgtga
    12001 cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa aatgagaacg
    12061 aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag gaacagatct
    12121 cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct gaagcggccg
    12181 aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca ttaggagcaa
    12241 tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt tttgatcctg
    12301 aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg acagtgatca
    12361 atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat tacggatatg
    12421 aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt tttctggaat
    12481 ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac aaaaaatgat
    12541 ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc gtaaaagtta
    12601 cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg agtcacaagg
    12661 aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg attcggaatt
    12721 ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt gtcacagtcc
    12781 ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa attaaaaatt
    12841 gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat aaataaatta
    12901 aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg tgttgtattt
    12961 atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca tactatataa
    13021 gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat tctcataatc
    13081 agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac acgatatatg
    13141 tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt ccaaagaact
    13201 aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat acaatacgat
    13261 cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa agatgatcaa
    13321 tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa aagcatgtat
    13381 tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca atggttcgct
    13441 gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag aagcagcaat
    13501 cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa tgacaaaaga
    13561 agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt gccgcttatc
    13621 cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga aaaaagcaaa
    13681 ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg gtgttttctc
    13741 catggatgga gacattgcac gattgccgga aattattccg attgttgaaa aatatggact
    13801 gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg caggaaccgt
    13861 caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat cgaaagctat
    13921 aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt tgaaagctag
    13981 aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag ctgcattggc
    14041 ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg aaaatgctaa
    14101 ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg aaacacctat
    14161 tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga agctgatcga
    14221 acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga caggcaggat
    14281 cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag tagcagttta
    14341 tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt cgtctattta
    14401 aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta gtaaaaaaga
    14461 tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca aattggttca
    14521 gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc gacagatata
    14581 cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt aatggattac
    14641 gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca tttggctgct
    14701 cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa cgtgactggg
    14761 ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac gccaagttca
    14821 atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac tcttcagcgt
    14881 cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga ttattattat
    14941 gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc ttatgcaacc
    15001 ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc aatcaaagaa
    15061 ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta tatgccagat
    15121 gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt tcatcgaaat
    15181 gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc tattcaaaaa
    15241 atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc aatagcagaa
    15301 tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt ttcgccgaaa
    15361 tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa attggtagag
    15421 acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat tggctatggt
    15481 atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa gtaaaaatag
    15541 aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt atgggcacag
    15601 tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca ggatccgcca
    15661 gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca ggactaacag
    15721 gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat atcgaacgga
    15781 tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt tattttccag
    15841 caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta tttggtcttt
    15901 cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg ttgatcaatt
    15961 ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc aagcttattc
    16021 ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac ttccaactgt
    16081 ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg ggcttgctag
    16141 caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga gaattgaaaa
    16201 agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc atgatcgttt
    16261 atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc gcaggaaaca
    16321 gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga agactggtca
    16381 cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt actggaatgc
    16441 gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc tttgctaaac
    16501 ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc atcgctattg
    16561 gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt gtcatttgga
    16621 ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa cctgatttgt
    16681 ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc attggaggga
    16741 cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg gggatagtat
    16801 tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta aaacattcga
    16861 attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg aggagtacgt
    16921 ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt tgtctacgat
    16981 gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt tactttgatt
    17041 tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc aagcaaccag
    17101 aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta gacaaagcat
    17161 gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga ttgaagacta
    17221 gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta gttctttttc
    17281 ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca aaaacaaagt
    17341 acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg aaagaaatga
    17401 gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata agagagatac
    17461 aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt tgcgctgatt
    17521 gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga atatcgaaag
    17581 tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt ttatttattg
    17641 tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc ccaaatgaca
    17701 gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga caacacggta
    17761 ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt atttttggaa
    17821 ccagctttta atgttttatt actcatacca tttggcattt atttaagata ttatttccgg
    17881 ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt tgaattgacg
    17941 cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga tgtgaatgat
    18001 ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt atttacattt
    18061 atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa gactgtctca
    18121 ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct tattaatttg
    18181 gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc tcatatctgg
    18241 tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac caatggatgg
    18301 acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga acgaatttct
    18361 ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg tttaagctgg
    18421 ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt gcagatgagt
    18481 gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt aaatatcttg
    18541 ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca cacatatact
    18601 gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag caaaaacgct
    18661 ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc acgaatgaat
    18721 aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc aaagggcttc
    18781 aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg aaaaaatatc
    18841 attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc tttgtttgaa
    18901 aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag tagggaacta
    18961 gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc ggagatccgt
    19021 gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct gcatcaccaa
    19081 cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa tgaacaagcg
    19141 ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac attggatatg
    19201 ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct gcagttttta
    19261 gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata catggaaaat
    19321 ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga aaattggctg
    19381 atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac aattggtcat
    19441 ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat tgccgattac
    19501 ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc aagagagaga
    19561 aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc gactgattta
    19621 gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga aattccagaa
    19681 gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt aaaaggaacg
    19741 gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga aaaattgggc
    19801 gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata cgatcgtaat
    19861 agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat tggtcttgtg
    19921 aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg ggcaattgca
    19981 gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac tgctcgtaaa
    20041 aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg tgtcacaatc
    20101 tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc ttcaataaaa
    20161 ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt catttcagct
    20221 actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc ttcaagcaac
    20281 tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc cggcttgaag
    20341 caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg atcaagaaat
    20401 agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc aggaatccct
    20461 tgttctaata caaaaacttg atatctcaaa aagcagctag ctgcgcgtat ccattcatcc
    20521 gctccaacta tttttttcat catattcctc cttgtcatga atagcagaga tgtattgatt
    20581 cctttattct tatcgtacca aaaatcgtgg agtatgacca aaaggaaatg aaaataaaaa
    20641 ttgagatatt gacagtgatc aatagaatgc gtatactaat taagtacgaa aaggatatga
    20701 tttgtttttt aagactcaca gaaaattctt tcttggctga aaaaagaata gtcactaatc
    20761 aaattgctcc ctttttctat tttggtagaa ataccgacgc agctcagcgt tatcgagttt
    20821 aagaggtaat gattacacat cattgcaatc aaggtggtac cgcgagtttt cgtccttggc
    20881 tgtgatggtg tttttttgta tttaatttat agaaagcagg taatgacatg aaacaattaa
    20941 gtagtgcaca agttcgacaa atgtttcttg atttcttcca atctaaagga catacgattg
    21001 aacctagtgc gtctttgatc cccgtgaacg atccaacctt attgtggatc aactctggtg
    21061 ttgcaacatt gaaaaaatat tttgatggtt cagttgtgcc agaaaatcca agaatcacaa
    21121 atgcccaaaa atctattcga acaaatgata tcgaaaatgt cggtaaaaca gcacggcacc
    21181 atacgatgtt tgagatgctg ggtaattttt cgattggtga ctatttcaaa aatgaagcca
    21241 tccactgggc atgggaattt ttgactgatc caaaatggat ggcattcgat ccagaaaaac
    21301 tttatgtaac agtttatcca aaagatacag aagcaaaacg catctggcat gaagaagttg
    21361 gcctgccact agatcacatt attgatgtag aagacaactt ctgggatatc ggtgcaggcc
    21421 catgtggtcc ggatacggaa attttctatg accgtggaga agcttataac gatttagcag
    21481 aagacgatcc tgaaaactat ccaggaggag aaaatgaacg ttatttagaa atctggaact
    21541 tagtattttc agaattcaac cataagcctg ataacacatt tgaaccactt cctcataaaa
    21601 acattgatac ggggatggga ttggaacgca tggtctcaat cgttcaagat gcgtcaacga
    21661 actttgagac agacttgttt atgcctatta tccacgccgt agaaaagcta agcaaacaag
    21721 taaaatatgg tgaaaaccca gtaacagata tttcttacaa agtaatcgca gatcatattc
    21781 gcgccctttc atttgctatt ggcgacggtg cattgccatc aaatgaaggg agagggtatg
    21841 tcttacgccg tttgcttcgt cgtgctgtca tgcatgggaa aaaattaggt attgaacaag
    21901 cattcttata tcgtttagtc cctgttgttg gggaaatcat ggtaagttat tatcctgaag
    21961 tacttcaaca aaaagaattt attgaaaaag ttatccgtac agaagaagaa cgtttcaatg
    22021 aaacaatcaa tgaaggtttg gaaatcttaa atcaagtgat ccaagaagta aaaaacgaaa
    22081 acgggacgac tctagcagga aaagacatct tcaaactata cgacacatat ggcttcccgg
    22141 tagaattaac ggaagaggtg gcagaagatg aaggactgaa agttgatcat gctggttttg
    22201 aaaaagaaat ggatgcacaa cgcgaacgtg ctcgctctgc ccgcagtact gaaaaatcaa
    22261 tgggggtaca atctgcttta ttgacagata tcaaagtaga aagtaaattc attggataca
    22321 cagaacaaga atcagatagt caattattgg tcatcgttaa aggtgagtct cttttgaatg
    22381 aagtcgcaga aggtgaagct caaatgatct ttgatcaaac acctttctat gcagaaatgg
    22441 gtgggcaagt agcggatcaa ggatggatca tgaatgaagt aggcgaaatc gtagcagttg
    22501 ttacagatgt tcaaaaagcg cctaatggtc aatttatgca caccgtagaa gtaaaagcac
    22561 caatgagtga aggacaaacc tatcatctat tgatcgatca atcgatgcgc aatcggatca
    22621 tcaaaaacca tacagcaacc catctactgc acaaggcatt gaaagaagta cttggcgagc
    22681 atgcaaatca agctggttct ttagtcgctc ctggacattt acgattcgac tttacccact
    22741 ttggtcaaat cacttcagat gaattagctg aaatggaaag aatcgtcaac gaaaaaatct
    22801 gggaagctat cccagttgaa acaattgaaa cagatatcga tacagccaaa aacatgggtg
    22861 caatggcttt gtttggtgaa aaatacggac atgacgttcg agtagtaaat attggcggct
    22921 ggtcaatcga actgtgcgga ggcacacatg tagcaaatac agaaaacatc ggaatcttca
    22981 aaatcgtttc tgaatcagga attggtgcag gcgtgcgacg aatcgaggct gtaacaagta
    23041 aagaagcgta cgaactactt gaagaagaag aaaaacaact aaaacaagta gcaacaattg
    23101 ttaaatcacc tcaattgaaa gaagttgttt caaaagcgga acaattgcaa cagcaagtaa
    23161 gagagctaca aaaggaaaat gaacaattag ctagcaagtt agcgaatcaa caagctggtg
    23221 atgtattcaa agatccagaa acgatcaatg gaaaaacaat cattgcagca caagtaaaag
    23281 tgaaagatat gaatcagctg cgtcaattag ctgaccaatg gaaacaaaaa aatatttcag
    23341 atattcttgt tttagcaaac gaacaagaag gaaaagtcag tctgctagcg gcaatgacga
    23401 aagaatcaaa tgaagctgga ctaaaagctg gcgacttgat taaagcaatc gcaccgaaag
    23461 taggcggtgg cggtggtgga cgtccagaca tggcacaagc tggcgggaaa aatcctgctg
    23521 gtattccaga tgcacttaaa gctgcgaaag aatgggttgc gcaacaatag ggcgtttacg
    23581 tttgacagaa aaacaaaagt tcaaacattg aacgaaacat gattatgggg gcgaagacaa
    23641 acaagtcttg ccctcatact tttttcaatt ggatggcgca tctaatcaaa tggtcggatt
    23701 cggatggtct ttagttgacg aaagtgacag aaatttttac gattagtata aataaaaagg
    23761 ggtgaaaaaa tgaatagtag aaataagacc tttcgactag tcttacgtgc gatcttgtta
    23821 gcaatcatca tcgtacaagc gatggttcct tggctggggt ttattccatt aggattcatt
    23881 agtttaacaa ttatccatat cacagtaatt attgctgcag tagtattagg cccaaaagat
    23941 ggcatggtga ttggcttgtt ttggggaatc gttacaattg ttcgtgccta tgccatgcca
    24001 acaacgccat ttgatacatt agtgttcacg aatccgatta tctcggtagt tcccagagta
    24061 cttgttggct tagtagcagg cttggttttc cactggattt atcaaaaaaa taaatcaata
    24121 acgatcagct cagcctttgc aggggtactg ggttcattgg tcaatacagt cttagtgtta
    24181 ggattcatgg gattatttta tacaggtgca acggcagatg cctatggtgt agactctgct
    24241 cttttattta aaaccttagc aggggttgca gcaatcaatg ggataccaga agcaataggt
    24301 gcgggaatca taacaccatt actagcaaaa gcgttatttg cagcaacacc gttgaaacca
    24361 gaataatgac catcttttaa tagtaatagg acgcacgata gatagaaaaa ggaagagagg
    24421 agaggaaaac aatcgtcctc tccatctttt tacctgagca acaagcaaac tagaaggggt
    24481 aaaaaacttg gctaagaaac aagaagaaaa aaagaaacaa ataccgcaac agcggacaaa
    24541 aaaaggagta ctagcgggta tcttaggatt ggttacgaat ctgatcttgt ttgtctctaa
    24601 gctaatgatc gggctttttt caggaagtgt ctccattatg gctgatgcag tgaacagtct
    24661 atcagatact gcttcatcca tattgacttt gatcggattt aaaattgctg caaagccagc
    24721 agatcaggaa catccttatg gacacgaacg cttcgaatat atcagtgggt tatttgtttc
    24781 gatcatcatt acttatgtag gatttcaatt tttagagtct tctgctgaaa aaatcatcca
    24841 tccagaaaat gtctctttaa cacccatcgt cttttttgtc ctaatcattt ccatcttttt
    24901 gaaatttgca caaggcaaaa tgtatcaggt tattgcgcaa tccattgatt ctgaaacatt
    24961 gagagctaca gcaacagata gttataatga tgtctttact acactggctg tattgctttc
    25021 agcagcaatc gaatgggtaa ctggatggcg tattgatgga tatataggtt ttgctttagc
    25081 attatatatc ctttatagtg gattgacgat gcttcgaaat tttgtatacg aactattagg
    25141 aagtcgccca acgccagcag agattgaaga aatggaagag catttaaatg cttgcgatga
    25201 tatacttggc tatcatgatt tattggtgca taactatgga cccaataaac gctttgcatc
    25261 agtccacatc gaagtagatg aatcaatgaa tttgaatgtg gctcataaga ttattgatct
    25321 gatagaaaaa gactttaaaa agtctttgga tgtggaactt gtctgtcact tggatccaat
    25381 gcctgttgat aacgaaaaat actataatat cttgcggcag ttaaagcaaa ttcttcttga
    25441 aacaggtaca gggcttaata ttcatgattt tagagtaatt catcaaggaa aaacgctgca
    25501 atttgatgta gtggtccctg agaaattcca gtttgttgat acagaactag aaagaatctt
    25561 acgtagtcaa atagaagaaa aaatcggaga ttaccaattg gaaattacgt ttgatcacaa
    25621 ttatctttta tattaaatga gaaactataa aaagactcct taaagttttt aatttaaaga
    25681 gtcttttttt cttttaattg tttatggaga gcctgacgtg caagattatc tgctccttta
    25741 tttttgtttt cgggcaacca ttgcaggatc aataaagaaa attcggatag aagttcttgg
    25801 attctttgaa ggtagggaag gaagagctcg ttcttcgttg cgtttttgtc gaccgtagaa
    25861 actagtgttt tgctgtctga aaaacagaaa atcgtttcat tctgtaagtc gtttttcttt
    25921 agaaattcta aagtttttaa aaagacttcg aactctgctt gatggtttgt ccctatagaa
    25981 agcgggatag atagctgttc ttgtttacct tgatagacaa tcaagattcc acctccacta
    26041 ggaccagggt tgccttttgt agaggcatca atgtatactt ttaacataaa aagagattct
    26101 cctttttgtt caaactaatg ttatggtaag attatatcat tactgaatcg gtgagaggtt
    26161 agagaatgaa aaaaaatatt cgatggcagc ctgaactggc acatacgatc atctattggt
    26221 cattgacctt gatcattctg ttttttagtc tgattctttc tttagaaaac acaggtcctt
    26281 attggaaaag caattttgtt ttaggtattt ttcttgtttt tctatttcta ggtttgcggc
    26341 gttcttttat tttaaaatca aactctgtga ttatacgtta tgctgctttt tggaaagacc
    26401 gagaaatatc tgtcggacag attcgatctt tgacgccaac taatactggg gtgcaaatga
    26461 tgttgcaaga tgagaaagcc ccatctgttt tcatgatgcg aaaaaaagat caagtagtcc
    26521 tttttgatca ttttgaaaaa aacggaccca aatcagaatc aattccttat ccttatacga
    26581 aaaaaagaaa aagctaattt taaaaatcag aacctaaaaa aacgaatttt tacaggaaaa
    26641 gaaaagagtg agacgtacgg ttcatcccgt ttagcgtctc actctatttg tttatctatt
    26701 catgcatact agtatcggta gtctgaacgt tgcctttctt gacatgggca gcttgtgttc
    26761 ctcgattccc ttcgatgatc tcaaattcga ccacttgatt ttcttccaaa gttttgaatc
    26821 cctcttcttc aatcgcagta aaatgtacaa aaatttcttc tgtgtcatca taactgataa
    26881 agccgtatcc ttttttgttg tcaaaccatt ttacaattcc tgtggtcaaa gcactcacga
    26941 cctttctaaa gtctgatcat agccttcatt ataaagagta tttataagta cgtcaaataa
    27001 attaaaaacc tgtaatttta tgtttttttt ctgaataaaa aaaggtataa ttggcatatc
    27061 ttaacaaaga agatattttg ttgaataaag ttcgtgaaaa ggggtaatca aatgaagaat
    27121 gatctgcaaa tttcacaaga aacagagcta gaaccgattg ttgaagtggc tagtaaatta
    27181 gatcttaagg aagacgattt ggaactgtat gggaaatata aggcgaaaat caatttttct
    27241 ggaatcaatc gatcaaagga taacgctgag gggcatttga tcttagttac ttccatcaat
    27301 ccaacaccag ctggcgaagg aaagtcaacg atcactgtag ggttaggaga cgcgctcaat
    27361 aaaatcaata aaaaatctgt tattgcattg cgagaaccct cacttggtcc tgtgatggga
    27421 atcaaaggtg gtgctgcagg cggaggatat gcacaggtat tgcctatgga agatatcaac
    27481 ttgcatttta ctggtgacat gcatgctatc acaacagcta ataatgcatt atctgctctt
    27541 ttagataatc atattcatca aggaaatgaa ttgaacatcg atgcccgccg agtgatttgg
    27601 aaacgggtag tcgatctcaa tgatcgtgaa ctgcgtaaag taattgttgg cttgggtggg
    27661 ccaatccaag gtgttccaag agaagatggg tttgatatca cagttgccag cgaaatcatg
    27721 gctatcttgt gtcttgcggc agaccttgaa gatttaaagg ctcgtcttgc aaggatcgtt
    27781 gtcggctata catttgaccg tcagcctgtg actgctggag acttgaaagc agaaggcgct
    27841 ctggcattac tgctgaaaga tgcaatcaag ccgaatcttg tacaaacaat ttacggaaca
    27901 ccagcttttg tccacggggg accgtttgcc aatatcgctc atggctgcaa tagtatttta
    27961 gctaccaaga cagcattgag attagcagat tacgttgtca cagaggcagg atttggtgca
    28021 gatcttggcg gagagaaatt tttagatatc aaagtaccta acttgaaaaa agcgccggat
    28081 gctgtggtga ttgtcgccac tgtccgtgca ttgaaaatgc atggcggaat gaaaaaagat
    28141 gaacttaaaa atgagaatct tgatgctttg aaagtaggtt ttgcaaattt aaagcgccat
    28201 atacgtaata tggaacaata tcagctacct gtgatcgtcg caatcaatga attcgtaaca
    28261 gatacagaca atgaactcac actgttggag cacttgtgtg aaaatcaggg gattcttgcc
    28321 aagagagcga gtgtatgggc agatggagca gaaggcggcg ttgatttagc aaaagctgta
    28381 gtacgattga ttgatagaaa agaagctaat tacaagccat tataccgcct agaagaaacg
    28441 atacaagaaa agacagaaac aatcgtcaag aaaatttacg gaggaaatgg tgttgttttc
    28501 agcaaaaaag cgcaaaaaca aatagaagag tttacgaaga atggatggga caaactgccg
    28561 atttgtatgg caaaaacaca gtattcattt tctgatgatc cttcactgct aggtgcaccg
    28621 gaagatttca ccatcacgat ccgcgaaatc atcccaaaat taggggcagg atttttagta
    28681 gccttgactg gagatgttat gacgatgcct ggtttgccta aaaaacctgc tgcattgaat
    28741 atggacgtga caaatgacgg agaagtgttg ggattgtttt aagcttgatt ataatctacc
    28801 atcgaaggag ctgtattttg actacagctt ctttttttag acgataggga attaattttg
    28861 tttacactag gatcattctt tttctttatt gtattttgag ctatactaaa gcataatagg
    28921 agggtatgat gaaaacgaca tttataagaa aaaccggttt ttacggtatg ggtagctcga
    28981 ttcagctaag aatcaacaat gaaaaacgca gtgttctcag tcatgaacaa aagataacgc
    29041 ttgatctgga agtgcccttt acgatgcagg tcacctttta ttggctaaaa agccccgttt
    29101 atacagtgaa agaagcaaag cctgcttatg tgatcacaat gaattacttg attcttcaaa
    29161 tctatccgtt tttatttcta gcaactgggt tgggggccgt tttcctacaa aatttatttt
    29221 tcagtttttt tgcagttatt gtgttgattg cgttcttttt ctatataaaa aaccgggcat
    29281 atttgatcaa ggaggaaaat tatggcaaac tctgatcttt ttttaatcag tttcaatcga
    29341 atcgaaaaat ggatgagaga cgagatggga aatgcacgaa atatgggatt taccgaactt
    29401 gtcagacgcc tagctcaaag aaaacaatta atgatcagaa aatacgaaga tgatctttta
    29461 cagcttgctc agttaaggaa tgcgatcgtc catgatcgga tcgcagtcga ttttgtcatt
    29521 gcagagccaa atgattggac agtcaagcga atccagctga tcgaacaaga actgattcag
    29581 cctgaaaccg tgctgcctcg atttgcaaaa cgtgtaacag gttttgaaca agatcttccg
    29641 ttacttgaac tgttaaagat agtagcagaa aaaaggtatt cacaatttcc gttatacaat
    29701 aaaggaaaat ttgtagcatt gattacttta cgtaatatcg ggttttggct agcaaaagaa
    29761 agccaaaaag gtccggttga tttaacaaat aaacgagcgt tggatttgat catccaaaac
    29821 ggaaagtaca caaattatca ttttgttcca gctaaaacac atatttacga ggttgaagcg
    29881 atgtttcgtg agcaagggac tttggaagcc gtacttatca ctaaagatgg gaatcccgat
    29941 ggtaatctgc tcgggatcgt acgacctcgt gatatttata aacaaataga aaaggattga
    30001 ttttttgtta attatttatt ggatattcag cgctttgcta gtaggagtgg atcagttggt
    30061 caaatggtgg atcactgata atctagcgct tggagagacg aaaaatctta taccaggtat
    30121 tttgtcactg aatcatattc gaaacactgg agccgcatgg agtatgctag aagggaagat
    30181 gtggttcttt actatagtga cactcattgc agtcgttgtg attctcacat tgatgattaa
    30241 aaatcgtgaa aaaggtaatc gctggttcat gattggattg agtttgattc tagctggtgc
    30301 gattggcaat tttatcgacc gtattcgtct tggctatgta gtagatatgt tccagacaga
    30361 ttttatgagc tttccgattt ttaacgtagc agatgtgaca cttgtatgtg gagtgatttg
    30421 tatgttaatt tatattattt tagatgaaaa ggatcaaaga aaaaaatgac agaacttaaa
    30481 acgacgattc accatgaatc tggtaggatc gataaagtat tgactaattt attcaccgat
    30541 tacagtcgtt cgcaaattca gctgtggctg aaaaatggag cggtttctgt caatggacag
    30601 ccagtcaaag caaattacaa agtaaaacaa ggagacgaga ttactgtctt gatccccgaa
    30661 ccagaaacat tagatgtggt cccagaaaat atcccgttga cgatcgttta cgaagatgaa
    30721 gatgtagcgg tgataaacaa acctcaagga atggtcgttc atccttcagc aggtcatacg
    30781 catggcacaa tggtcaatgc gctgatgtac catatcaagg atctttctac gatcaacggc
    30841 gttattcgtc caggtattgt tcaccgaatc gacaaagata cttccggact gctaatggtt
    30901 gccaaaaatg accaggcaca cgaatcatta gctcagcaat taaaagataa gacctctttg
    30961 cgcaaatatg ttgctttagt ccatggagag attcctcacg aaaaaggaac catcaatgcg
    31021 ccaatcggcc gttcgaagga aaaccggaaa atgcaggcga taagagaaga tgggaagtcg
    31081 gctgtcacac attttactgt attggaacgt ttcgaaggat ttactctggt tgaattaaaa
    31141 ctagaaaccg gaagaacaca ccagatccgt gtgcatatga agtatatcgg ttatccgtta
    31201 gctggagatc cagtatacgg accgaagaaa actttgaaag gcaatggtca gtttctccat
    31261 gcgcaaatgt taggttttac gcacccgact acaaacgaaa agatgatctt tgaagcacct
    31321 cttccagaag tttttgaaaa aactttagaa aaattaagaa aaaacattgc attttaattt
    31381 agataacggt atagtaatta acaacgaaag cataaaactt aatagaattc ctttaagttt
    31441 agtcccgtga ggctaagaag ggtgggagca aggatacgta tggtgcgcca taagtagatt
    31501 gctcattgac atagtatagc tatcagtgta tcagtatacg ctcagtctaa acattcctcc
    31561 tgtcctctta gggcaggagt ttttttatgc aaaaaagtag ggggaatgaa aatgcaagca
    31621 aaagaagtag tagatcaggt aaccatgaag cgagcattga ctcgaattac ttatgagatt
    31681 atcgagagaa accatagtat ccaagatatc gtattggtag gtatcaaaac acgaggaatc
    31741 tacattgcat caagaattgc cgaacgcctg aagcagctag aagatatcga tattcctgta
    31801 ggagaactgg atatcacttt ataccgagat gacaaaaaag aaaatccaga agaaccggaa
    31861 cttcattctt ctgacatccc agtttcctta gaaggaaaag aagttatttt gattgatgat
    31921 gttttgtata caggacgaac gattcgagca gcaatggacg cagtaatgga ttttggcaga
    31981 ccaagaaaaa tttcattagc agtcctggtc gatcgtgggc atcgagaatt gccaatccgt
    32041 gcagattatg ttgggaagaa cattccaaca tctcgggcgg aagagatttt agtagagatg
    32101 caagagcttg atggacaaga tcgcatcatg attttgaaag aggaagatta gaggagagag
    32161 aaacatgtcg gagaaaaaag gatttcataa tgatgacgtg gtgttagata tccacgatcg
    32221 cccaacccca ggacattggg taggattaag tttacaacac ttgttcacga tgttcggagc
    32281 aaccgtgtta gtccccatct tagtaggtat cgatccaggt attgcgctag tcagttcagg
    32341 actaggtaca ttggtgtact tatttactac taaaggaaag atacctgcgt acttaggaag
    32401 cagcttcgct ttcattgcag cgatgcagct tttgatgaaa acagatggtt atccagcgat
    32461 tgcacaagga gcagtcacaa ctggattagt ctatttgatt gttgcgctga tcatcaaaaa
    32521 gatcggttca gcatggctgg ataaaatctt gcctccaatc gtcgtcggtc cagtcatcat
    32581 ggttatcggg ttgggacttg cggcaaatgc agcaacaaat gctatgtata atcagggcac
    32641 gtatgatttc aagtatattg ctgtagcgct gatcacatta ggattaacaa ttttcttcaa
    32701 catgtggcta agaggttttc tcggattgat tccgatttta ctaggtatta ttagcggata
    32761 catcgtagcc ttgctgtttg gaatcgtgga tactaagcca atcgtagacg ctgcctggtt
    32821 tgctgttcct aactttgaga ttccctttgt acaatatgaa ccaaagctat atcttggagc
    32881 aatcacaaca atggcaccca tcgcttttgt gacgatgaca gagcatatcg gccatcttat
    32941 ggtattgaat aaactaacta aacgtaattt ctttgaagaa ccgggtcttc ataagacgtt
    33001 gacaggtgat ggattagcac aaatcgtggc agcctttgtc ggaggtcctc ctgtaacaag
    33061 ttacggtgaa aacattggtg ttctggctat cacacgtgtc catagcgtgt ttgtgatcgg
    33121 tggagctgca gtatttgcag tcattttagg attcgtagga aaattaagcg ctttgatttt
    33181 aagtatccct ggaccagtca tctcaggaat cagttttatc ttatttggag taattgccgc
    33241 aagtggaatg aagattttaa tcgagaacaa aatcgatttt gataaaaaga aaaatctgtt
    33301 gattgcttca gttatcttag tagtaggaat tggcggactc gtctttgaag taggcacatt
    33361 tacattgtcg gcaatggcat tagcaactgt acttggcatc attttaaatc ttatcttacc
    33421 agaaacttca cgaagcgaag aaaactaagg aggaaacatt atgatcatca aatcagaacg
    33481 tatcagctta aagcatttat tgaccgttga ggcacttact gatcaagaag ttatgggctt
    33541 gatccgcaga gggcaggaat tcaagcaagg tgctaattgg actccgcaaa agcgccagta
    33601 ctttgctaca aacctctttt tcgaaaatag tactcgcaca cataaaagct tcgatgtagc
    33661 ggagaaaaaa ctagggctag aagtgattga atttgaagca agcacaagct ctgtccaaaa
    33721 aggggaaaca ctatacgata cagtactgac gatgtcagca ttaggcgtag acgtagcggt
    33781 tatccgtcat ggtgatgaga actattatga cgaactgata caaagtaaaa caatccagtg
    33841 ttcgattatc aatggaggag acggaagcgg acagcatcca acccaatgct tgcttgattt
    33901 gatgaccatt tatgaagaat ttggtcattt tgaaggtctg aaagttgcca tcgtaggtga
    33961 tatcactcac tctcgcgtag ctaaatccaa tatgcagatg ttaaaacgtc taggcgcaca
    34021 agtattcttc tcaggtccta gagaatggta cgacgatgaa ttcgaagtgt acggacatta
    34081 tatgccattg gatgaactac tagatcaagt tgatgtcatg atgatgcttc gggtgcaaca
    34141 cgaacgccat gatggaaaag aaagtttctc aaaagaaggc taccatcagg aacatgggtt
    34201 aacagttgag cgtgcgaaga agttgcaaaa acatgcaatc attatgcacc cagcaccagt
    34261 taaccgtgat gtagaattag ctgattcatt agtggaagga ttacagtcgc ggatcgttca
    34321 gcaaatgagc aatggagtat tcgtcagaat ggcaatctta gaagcagtgc taaatggaaa
    34381 agcgtaatta taggaggatg aaaaaatgaa aacactcatt aaaaacggtc agatcaatac
    34441 acgaaaaaat atgacgacac cagcagaaat ttggatagaa gatgggcgaa tcaaagcaat
    34501 cggtacagga ttctcagaag ccgaatttga tgaagtgttt gatgcaaagg gacaattgat
    34561 cacacctggt ttagtggacg tccatgttca tttgagagag ccaggattta catacaagga
    34621 gacgatcgaa gctgggactc gctcagctgc tcgtggcggt ttcactactg tatgcgcgat
    34681 gccgaattta aatcctgtac ctgatacggc agaaaagctg agacaagtat atgacatcat
    34741 tagaaaagat gcagttgtga aggtattgca gtatgcgcca atcacagaaa atctgcgaag
    34801 tgagaaatta gttgatcaag aagcactgat tgaagaaggt gcttttgctt tcacaaatga
    34861 cggtgtaggt gtccaaacag ctgggacgat gtatctggct atgaaagaag ctgcaaaaaa
    34921 caataaagcc ctagtagccc atacagaaga tgaatcttta ttatttggcg gcgttatgca
    34981 cgctggcaag aaggcagaag aacttggtct tcccgggatc ttaagcgtaa ccgagtcttc
    35041 tcaaattgct agagatctgt tgctagctga agcaactggt gttcattacc atgtttgcca
    35101 tgtttctact aaagaaagtg tccgtgtaat cagagacgca aaaaaagcag gaatccacgt
    35161 aacagcagaa gtttcacccc atcatcttat tttgatcgac gaagatattc ccgaagattt
    35221 cggcttttgg aaaatgaacc cgccgctaag aggacgggag gacagagaag ctttgatcga
    35281 aggcttgctt gacggtacga tcgattgcat cgctacagac catgcccccc atggattaga
    35341 agaaaaaagc caaagtttca tgaaatcacc atttggtatc gtaggaagcg aaacagcgtt
    35401 tcaactgatc tatactcatt ttgtagaaac tggtcgattc acgttggaac aagtgatcaa
    35461 ttggttggca gttaaaccgg ctgagatttt tggtttgaat gcaggaacgc taacggttgg
    35521 tgcccccgct gatgtagcag tttttgatat tacacaaact tgcacgatcg ataaagaaga
    35581 ctttttatca aaaggggaga atacaccttt tatcggctgg aaagtaaaag gcgaaacaca
    35641 aatgactttt gtcaacggaa aacttgtgtg gcagaaggga gaataaaagt atggaacgtt
    35701 tgcttatatt agaagatgga acagttttcg aaggaaaggc ttttggtgca gatgctagtg
    35761 tcttcggaga aatcgttttt acaacaagta tgactggtta tcaagaaact atcactgatc
    35821 aaagttttaa cggtcaaatc attacattta cctatcctat ggtgggtaat tatggggtaa
    35881 atagagatga ttatgaatcg atttctccaa catgcaaagg agtagtagta aaagaacatg
    35941 cacgtgtagc ttcaaactgg cgaaaccaaa tgacgctaga ttcatttttg aaacaaaaag
    36001 gaattcctgg aatatcaggt atcgatacgc gcgcccttac tcgcaaaatc cgtgaagtcg
    36061 gaacgatgaa agctagtata gttgatgctg gagattcctt cgaacatgca tttgatcagc
    36121 tgaaagcaac cgttctagca accaatcaag tgcagcaagt ctcaactaac aaaccttatc
    36181 caagtccagg aacaggtcgg aaagtcattg tcattgactt cggcttgaaa catagtattt
    36241 tacgagaatt gagtaaaaga aactgtaacc tcacagtact tccctataac acagatgccg
    36301 agacgatttt agcgctatca ccagacggag tcatgctgac gaatggacct ggtgatccaa
    36361 aagatgtgcc agaagcaatc gaaatgatca aaaaaatcca aggaaaagta ccgatttttg
    36421 gtatttgtct cggtcaccag ttatttgctt tagccaacgg tgcagatacc tataaaatga
    36481 aattcggaca tcgaggatta aatcacccgg tacgagaagt agcgaccgga agaattgatt
    36541 ttacttctca aaatcatggc tatgcagtcg atgaagccac gattgatcca gaaaaactca
    36601 tcgtaactca tgtagaagta aatgacggaa cagtagaagg agtcaaacac agagattatc
    36661 ccgctttcag tgtgcagttt catccagatg ctgcccctgg tccgcatgat gcactacatt
    36721 tatttgatga atttatggaa atgatggacg caggaaagga gcagtaaaca gatgccgaaa
    36781 cgtacagata tcaagaaaat tatggtgatt ggatctggtc cgatcatcat tggtcaagcc
    36841 gcagaatttg actacgcagg aacacaagcc tgccttgcct taaaagaaga aggatatgaa
    36901 gtggttttag taaattctaa tcctgcgacg atcatgacgg ataaagaagt ggcagatcaa
    36961 gtatatatcg aaccgatcac acttgaattt gtatcaagga ttcttcgaaa agagcgtcca
    37021 gatgctctcc ttccaacttt aggcggacag acaggcctca atatggcaat ggagctggca
    37081 gcatcaggta ttttagaaga attgaacata gaacttctag gaacaaagct ttctgcgatc
    37141 gatcaagcag aagatcgtga tctattcaaa cagttgatga aagaattgaa tcagccaatc
    37201 cccgagtctg aaatcgtcaa tacagtagaa gaagctgtag attttgcaaa taaaatcggc
    37261 tatcctgtca tcgttcgtcc agcctttact ttaggcggaa ctggtggagg tatgtgtgaa
    37321 aatgaagaag aattacgtat cgtatcagaa aatggattaa gtctttcccc cgctacccaa
    37381 tgtttgattg aacgaagtat tgcaggtttt aaagaaattg aatatgaagt gatgagagat
    37441 tcggctgata atgcaatcgt tgtctgcaat atggaa
//
LOCUS       DBGZHO010000022        34660 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.022, whole genome shotgun sequence.
ACCESSION   DBGZHO010000022 DBGZHO010000000
VERSION     DBGZHO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.022"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(313..2205)
                     /locus_tag="ACN3HL_001291"
     CDS             complement(313..2205)
                     /locus_tag="ACN3HL_001291"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006180.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="ACN3HL_001292"
     CDS             complement(2202..3929)
                     /locus_tag="ACN3HL_001292"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006181.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="ACN3HL_001293"
     CDS             complement(3945..4595)
                     /locus_tag="ACN3HL_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HHC8006182.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="ACN3HL_001294"
     CDS             4799..5095
                     /locus_tag="ACN3HL_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHC8006183.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="ACN3HL_001295"
     CDS             5287..5907
                     /locus_tag="ACN3HL_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HHC8006184.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="ACN3HL_001296"
     CDS             complement(5999..7165)
                     /locus_tag="ACN3HL_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHC8006185.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="ACN3HL_001297"
     CDS             complement(7177..7530)
                     /locus_tag="ACN3HL_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HHC8006186.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="ACN3HL_001298"
     CDS             7658..8680
                     /locus_tag="ACN3HL_001298"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HHC8006187.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="ACN3HL_001299"
     CDS             8699..8860
                     /locus_tag="ACN3HL_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006188.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="ACN3HL_001300"
     CDS             complement(9119..9553)
                     /locus_tag="ACN3HL_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006189.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="ACN3HL_001301"
     CDS             complement(9663..11522)
                     /locus_tag="ACN3HL_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HHC8006190.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11523..11663
                     /locus_tag="ACN3HL_001302"
     CDS             11523..11663
                     /locus_tag="ACN3HL_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HHC8006191.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11640..12799)
                     /locus_tag="ACN3HL_001303"
                     /pseudo
     CDS             complement(11640..12799)
                     /locus_tag="ACN3HL_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(13106..14530)
                     /gene="araA"
                     /locus_tag="ACN3HL_001304"
     CDS             complement(13106..14530)
                     /gene="araA"
                     /locus_tag="ACN3HL_001304"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HHC8006192.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14546..15244)
                     /locus_tag="ACN3HL_001305"
     CDS             complement(14546..15244)
                     /locus_tag="ACN3HL_001305"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HHC8006193.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15201..16862)
                     /locus_tag="ACN3HL_001306"
     CDS             complement(15201..16862)
                     /locus_tag="ACN3HL_001306"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HHC8006194.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17080..18480
                     /locus_tag="ACN3HL_001307"
     CDS             17080..18480
                     /locus_tag="ACN3HL_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HHC8006195.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18732..19811)
                     /locus_tag="ACN3HL_001308"
     CDS             complement(18732..19811)
                     /locus_tag="ACN3HL_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8006196.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19897..20856)
                     /locus_tag="ACN3HL_001309"
     CDS             complement(19897..20856)
                     /locus_tag="ACN3HL_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HHC8006197.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDTLIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20868..22379)
                     /locus_tag="ACN3HL_001310"
     CDS             complement(20868..22379)
                     /locus_tag="ACN3HL_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HHC8006198.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22401..22964)
                     /locus_tag="ACN3HL_001311"
     CDS             complement(22401..22964)
                     /locus_tag="ACN3HL_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HHC8006199.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22970..23833)
                     /locus_tag="ACN3HL_001312"
     CDS             complement(22970..23833)
                     /locus_tag="ACN3HL_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006200.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23847..24743)
                     /locus_tag="ACN3HL_001313"
     CDS             complement(23847..24743)
                     /locus_tag="ACN3HL_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006201.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24918..26207)
                     /locus_tag="ACN3HL_001314"
     CDS             complement(24918..26207)
                     /locus_tag="ACN3HL_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006202.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26179..27696)
                     /locus_tag="ACN3HL_001315"
     CDS             complement(26179..27696)
                     /locus_tag="ACN3HL_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HHC8006203.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27894..28784
                     /locus_tag="ACN3HL_001316"
     CDS             27894..28784
                     /locus_tag="ACN3HL_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HHC8006204.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="ACN3HL_001317"
     CDS             complement(28857..29681)
                     /gene="nadE"
                     /locus_tag="ACN3HL_001317"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HHC8006205.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29693..31165)
                     /locus_tag="ACN3HL_001318"
     CDS             complement(29693..31165)
                     /locus_tag="ACN3HL_001318"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HHC8006206.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31802..32164)
                     /locus_tag="ACN3HL_001319"
     CDS             complement(31802..32164)
                     /locus_tag="ACN3HL_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HHC8006207.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32387..33139
                     /locus_tag="ACN3HL_001320"
     CDS             32387..33139
                     /locus_tag="ACN3HL_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHC8006208.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33279..34202)
                     /locus_tag="ACN3HL_001321"
     CDS             complement(33279..34202)
                     /locus_tag="ACN3HL_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006209.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34217..34489)
                     /locus_tag="ACN3HL_001322"
     CDS             complement(34217..34489)
                     /locus_tag="ACN3HL_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006210.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10229 a         7212 c         5980 g        11239 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc tagatgaggc aacataagta tacggtcatt ttctaagaac tcttcttctg
    12061 gaaaatcagt caagtattta gccagatgtt gtttttccaa tgcttgcata acagcatatt
    12121 tatcaacaat ttcacttctt cctacattga taagtacagc atcttttttc attttttcta
    12181 tattcgcctg atcgatcaat ccttttgtat cttctgtcaa cggcagcatg actacgatgt
    12241 aatccgaggt agaaagaact gtttctaaat ctgcttgccg aacataatcc aactgggcat
    12301 cgcggataga ataacccaag acatccatcc ctaagctata gcaacttagc gctacttttg
    12361 tgcctatcgc tccaagacca agaagaccga tggttttgcc ttgcaattct cgtcccacat
    12421 aagcacttct tttgttttct gcctgttcta aaatattagg acctgttagt gtttgtacca
    12481 tacgacttgc ttcgattatc ggacgggaag ataagagcaa acagcacaaa acaagctctt
    12541 ttactgcatt agcatttaca cctggtgtat tcatgacgat cgtcccgttt tcagaagctt
    12601 tttcaacgtt gatcgtgttc accccaacac cagctcttga aattgctagc aaatctggtg
    12661 taagccattc atctttcact ttcgtactac gaataactat tccttcggct ggcaaatcat
    12721 ctattatttt gaaatattcc ccttgtaact tttctatctc ttgttctgga atagcatcaa
    12781 tcaaatgaac gtgatacata aaaccccctc cttactaaca agtatctcga aatttctgca
    12841 attagacaac tgtttaccat ttgacttcct agaagcaaaa agagcagtta gagcagagta
    12901 ggctgagtga taaaaataag gctatgacaa gttactgcca taagccttat tttcgagagc
    12961 aaaatattga gggtgagata tcttgataaa tggtgttccg ttagctgaca ttgataataa
    13021 gactaaattt caaaaaagtt gaaaagcaaa tttcgtcaat ctcttcttat ttcttaaaac
    13081 taagtggctt tttcacaacc tctttttatc taataaccac tgtttccaac tcaactaatt
    13141 ttgcccacgt ttcaatttga tctgttgtta gatttagcga gacaacggta tgatgaccgc
    13201 cacctgcctg aatccatgaa tggacacctt catggaaatt cggtttagtt ttccataaca
    13261 cacgtgcaac aggtaaatta ggtgcttcag tcgttggttc aaaggcttct acttcattga
    13321 tcagcagttt ataatgcgta ccgaaatctg ccatcgatac gactacccct tctcctgctt
    13381 tcccatcaaa tacaagacgc gccggatctt ctctatctcc cattgataaa ggagaaacaa
    13441 cgattcttgg tttcgtcgca gcaagcgtcg gatctacttc catcatatgg gattccaaga
    13501 ttgcttcttg gccactagct agctcgtaag tataatcttc catgaatcct gtatctttcc
    13561 ctcgagccat gattttcagc aaccgatcaa tcgctgcagt tttccagtcg ccttccccag
    13621 caaaaccgta tccttctgcc atcaaacgtt gtacagctag tccaggtagt tgtttcattc
    13681 catacaggtc ttcaaaatta gtcgtaaaag cgttatagcc tccttcttct aagaaacggc
    13741 gaataccgat ttcctgctga gcttgtactt ttacatgttc ctcccatgtc ttttcttcat
    13801 aatcaccata gtcgaaggta tacaattcct tgtactcttc aaataattga tcgacttctt
    13861 cgtctgatac gcgatcgatt acttgtacaa gatctccgat accaaaataa tcaacagtcc
    13921 aaccaaattg aatctgtgct tccactttgt ctccttctgt gacacccacg tttctcatgt
    13981 tgtcaccaaa acgagccact tttattccaa aactttcatt ataggctact gcaacatcca
    14041 tccaatcagc aatctctttt tggatctcag gtcgtttcca gtagccaacg acgattttat
    14101 tttgtttatt taatcgagca ttgatgaacc catattcgcg gtcaccatga gcggattgat
    14161 ttaaattcat gaaatccata tcgatcgttt tccaaggaat gctttcgtta tattgcgtag
    14221 ctaaatgaag caatggtttt tgtagaagct ttgtcccgcg gatccacatt tttgctggtg
    14281 agaaagtatg catccaagtg atcacacctg ctacttcttc tcgataattg acctctttca
    14341 tgatttttgt gatcgtatca gcagtaactg ctaattcttg aaggcggatt ggataaggca
    14401 attggccatt ttcattcagt tcatcgacca tttcttgtgc atgtttcttt acttctcgca
    14461 gtgcttcttc cccatataaa tgctgtgatc ctacaacaaa ccaaaattct ttttctccaa
    14521 tattcaacat aattagccac tccttttatt tgttttgtcc gtaatacgca ttttttccgt
    14581 gttttcgtaa ataatgttta tctaaaatcc gttgaggcag ctcttctgaa aatgaattga
    14641 gctgtctggt aaataaattc atcttgcata cttcatctag tacgactgcg ttcattaccg
    14701 cactttgcgc atctttcccc caagtaaatg gaccgtgtcc gtgtaaaagt acccctggaa
    14761 ttgctaaggg atcaattttg cgttctttga atgtttctat gataactttt cctgtttcat
    14821 attcgtaccc gctgtcgatt tcctgttgtg tcaaaaatcg agcacaaggt accgatccat
    14881 aaaaagtatc tgcatgcgtc gtccccatcg caggaacatc caatcctgct tgtgcccaga
    14941 tcgtcgccca tgtcgagtga gtatggacga ttcctccgat ttgaggaaat gaacgatata
    15001 aaacagcatg agtaggcgta tccgaagagg gattgagttt accttcaatg atatgattgt
    15061 ccaagtccac aacgaccatg tcgtctgctg tcatctcttc ataactgact ccgctaggtt
    15121 tgataacgaa atatcgtgtt tcaggatcaa aagcgctcac atttccccat gtatatttga
    15181 cgagtccgtg tttaggcaag tcaagatttg cttggtatac ttcttctttc agttgttcca
    15241 gcattttcta tcactccttt ttcttgcaat tgatgaatcg ctgttttttc aatgtcgatc
    15301 ccctcacggt aacgtctcat aaatatctga tagcctgcta tttcttctgc tgaaggtgtg
    15361 atggtgattc cttggtcttg tccaaacacg tcttctgcca agaagttttc taaagacttc
    15421 ccatgtcgat ccatcatata ggctgctaat aacgcgattc cccacgctcc accttctccg
    15481 gctgtgtcca tcactgtaac tggtgcctcc atagcagatg ctagaatccg ctgtccaact
    15541 tctggtgttt taaaaatccc cccatgcccc actaaacgat caatttggac attctcagat
    15601 ttcaatatat ccattccgat tctcattgca ccaaaagcac tggctaaatg gatccgcatg
    15661 aaattcgcta aatcaaaacg gctacctggt gtacgtacaa ataatggcct tccttcattt
    15721 actcctgtaa tgttttcacc ggaaaaataa ccataagaaa gtaatccccc gcaatccgta
    15781 tcgccttcta gcgctttgtt gaataatacc gtgaataatt tatctctgct tatctccata
    15841 cccaaagaat tggtaaattc ttcaaaaata ctgacccaag cattgatatc cgaagagcag
    15901 ttattcgtat gaaccatgcc tactagttct cctgaaggtg tagtgaccat gtcgatttcc
    15961 ggatggacat tttctagttc tttttctaat acgatcatag cgaaggcgga agtaccagcc
    16021 gaaatgttcc ctgtcccttt ggctacactg ttcgtagcga ccataccggt tcctgcatcc
    16081 ccttctggcg gacaaaccgg gattcctggt ctcaaatttc ccgtagggtc gatcagataa
    16141 gcccctgatt cgcttaactt gccagcttct tctcctgcta ctagaacttt aggcaaaatg
    16201 tgatccaagt caatcgctac gtgcgctttt tcgattaact gaccaaaaat atttttcatt
    16261 tcttgatggt aggttttcgt tgaaggatcg ataggaaaca tgcctgatgc atctcctacg
    16321 cctagtactt tctcaccagt aagctgccaa tggacataac ctgcaagcgt tgtcaaaaaa
    16381 ttaatttctt tcacatgttc ttctttattc aaaatagatt gatacaaatg agcgatactc
    16441 catctctgcg gaatattgta ttgaaatttt tccgttaata ttcgttctgc ttcttcagtg
    16501 attgtatttc gccaagtacg aaatggtact agtaactgtt ccttgctatc aaatgctaga
    16561 taaccgtgca tcattgcact gaacccaatc gacccgattg tcgtaagatt ctcgccatag
    16621 atttcgaata cttctgctgc catttttcgg taactgacgc gcagtccttt ccaaatatct
    16681 tctaatgaat aggtccagat accattttct agtttgtttt cccactcata actaccagcg
    16741 gcaataggag taaaagatga atcaatcaat acagctttga tcctagttga tccaaactca
    16801 atccctaaag atgtacgacc atctatgaca tctaacatac tttgcgcatt tacttccttc
    16861 ataatgattt aactccctcc ttctcgtcaa acctgatcaa accgtctttt tagtagcgct
    16921 tacaatgatt attgtatact tttgtacgta catgtcaagc agttatttac aagaatacaa
    16981 taaaaaacac ttgttttgta cgtacataag ttataaaatg aaattgctta caaaatctga
    17041 tcaaccgcct tctcgaaatt ctagaaggag agaatactta tgaaaaaaga aaaaaaagtt
    17101 tcctcatcgt ttatttattt ttttggcgca tttggcggca ttctatttgg atatgatatt
    17161 ggtgttatga ccggcgcctt acctttttta cagcatgatt ggggtttggc aggtaaagct
    17221 tctttgatag gatggatcac gtcttcggtc atgttaggtg cgatccttgg cggctcttta
    17281 tctggtcttc tttctgataa gcttggacga cgaaaaatga ttcttctttc tgcacttatt
    17341 tttatggctg gttctgtcct ttctgcatct gcccctcaca atggttctta ttttctgatt
    17401 gcagcaagga ttcttctagg tttagctgtt ggcgctgcat ctgccctagt tcctgcttat
    17461 atgtctgaaa tggctcctgc tagactaagg ggaagattgt cagggatcaa tcaagtgatg
    17521 attgcttctg gcatgctcct ttcctatgtt gcagattatt tgctaaaagg gttgcctgaa
    17581 acgatggctt ggcgcgtgat gttagggctc gctgctgtcc ccgcgctgat tttatttttc
    17641 ggtgttttag ctctaccaga gtcaccgcgt tttcttatgc aatctggccg cttggaagag
    17701 gcaaaaagag tattgaacta tattcggaca ccaaaagaag ctgaacagga attcgaacaa
    17761 atccagctga atgtcaaaca agaaaagaca accggaactt cttggcatac tttgttttta
    17821 gaaaaatatc gttccttagt cattgccggt attggtgtag cagtattcca gcaatttcaa
    17881 ggagctaatg ctatttttta ctatattccg ctgatcgtag aaaaagcgac tgggcatgca
    17941 gcgagcgatg cattgatgtg gccgatcatc caaggaatca ttttagttgc tggttctttg
    18001 ctctttttgg ttattgcaga caagttcaat cggcgaactt tattgaaaat aggcggtagc
    18061 gtgatgggac tttctttcat cctaccagct gttttaggaa ctgtactgga tgctcataca
    18121 aattcgttgt tgattctctt gtttttatgt atttatgtcg cattttattc ttgcacatgg
    18181 gctccactga catgggtaat cgtaggcgaa atattcccac tagctgtccg cgggcgagca
    18241 tctggcctag cctcttcttt taattggatt ggttctttcc tagttggctt gctttttcct
    18301 gtgatgactg cttctatgtc tcaagaaatc gttttcggca tttttgggat catctgcttt
    18361 ttaggggttt tatttattca agagatcgta ccagaaactc gtgggaaatc tttagaggaa
    18421 atcgaacaaa gtgcatctaa aaaaacttat cctaaacgta tttctatcca tcattcttaa
    18481 agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaaccgctt agtttccagt
    18541 cacaaggaac aatttcaaaa aacagcttct catgtttgat gaatattgtg acttgtgacc
    18601 agttggtagg agaacaccgt ttagtggaga ggtggtgaaa gaaacgttca gccttgagcg
    18661 atgacaaaag ctctcacaaa cattgcgacg agtaaccgta ggagcaataa gaggcggtaa
    18721 aaacccgtct cttatttttc gttttctttc actgtttccc gttcaactag tacaggttca
    18781 tagagaatat ttggctgtgc ctgtcctttt tcaatcgttg tgacgatcca ccgtgcggca
    18841 tcttgtccca acttttcttt tggatgcgtc aatgttgtca attttttatt ccctaaatgg
    18901 cttaaagaag aatcgtctgt tcctacgatc gataggtcat ctggaatatg atagccattt
    18961 tctgtcaact tatctagcat taaactagct atttgatcgt tatagcaaat gatgccatct
    19021 aaagcttgtt cttctttcaa ccgttgtact gttttttcag cgattgtttc tcgtgtttcc
    19081 gtggtgaaag taatgatatc ttccgtcaaa aaacgcacat tatactgttc acacgcgctg
    19141 ataaaacctt tcatcctgta ttttccttga agatcgtcga tttttgtgat gaacaacaga
    19201 cgctgatgtc ctttttttat caaatattct gctgccataa aaccgacttt cacatcatct
    19261 aaacaaatat aagaggcatt taactcttca taagcagcat tgatcatcac catcggaatg
    19321 ccttgttctc tcaaagcaac ataaagtgct aagtttgggt tatactgatt acttttcgta
    19381 ggctcaacga tcaaaccatc taccccataa gcaatcattt tcttcaaaca ctctttctcc
    19441 aattcgtgat cgttattcgt actggctaaa agcaatgaat acccagattc tcgtaattca
    19501 ttttcgattc ctcggataat cgacggaaaa atataatcag agagatatgt ggtgatgaca
    19561 ccgatcgttt ttgttctgtt caatggtgtt ttttctttct tatagctgtc atctacatat
    19621 gtgcccgacc ctttttcttt acgcagatag ccctcattta ccaacacagc gattgcttgc
    19681 cgaatcgtat gtctgctgac gtcatatatt tcttgcagct tgaattctga gggaatggtt
    19741 gtatttactt cgtattcctc acgaaggatc ttttgtttta tctcttctgc aatatcttga
    19801 tattttgcca tttgccttgc ccctttttat ttgtacgtac atatatcata acgagtctgc
    19861 aaggtttatt caagcaaaaa tcaaggtttc ttgtgctcat aaggcatacg gaacaggttc
    19921 accaaattct ggaaatcctt gctcattcca cgtaaagcat tgcgcgttcg cgtgccgatt
    19981 aggattgtct aacggatccc ctttttggtt cttctctggt cgagcatgat agatcaaagt
    20041 atcaaagcac ccgtcttctg aaaccgtaaa cgagttgtga ccaggaccaa attgcttatt
    20101 tttttcagaa gaaacgaata ctggctccga taatttatgc catgattctt ttaataaaag
    20161 attcttgtgc tcatcagccc acagcaggcc catggcatag ttttcatctg ttgcactacc
    20221 agaatacgta atgaatattt tcccattgcg agtaaggact gctggacctt catttactga
    20281 aaaaccccgt ttttcccatt catactcagg tatagaaagg aggatctgct tcccctttaa
    20341 cgtccaagga ttatccattt cggatagata aagattagaa ttcccagtaa tttcaggatc
    20401 ttgttgggcc cacacataat atagctttcc ttgagaagag aaagttgttc cgtctaaact
    20461 gaaagtttcc cttttcgttt ttatttgtcc cttttctatc caatctgtat tcattggatc
    20521 tatatgctga ttttcaagta cgaacatgcg gtgatgatga gattcatcac gtatagtttt
    20581 atgattgctt gcagcaaagt aaatatacca ttttccattg atataatgga cttcaggtgc
    20641 ccagatcaat tcactcatcg gtccttcttc atgagcctgc catacaatca ggcttgcagc
    20701 atgttctaat tcattcagtg actttgccct tcttaattca atcacttggt agcctggaac
    20761 cgatcctgta aaataataat aaccatctgt atgtttatat acccaaggat ctgcccgttg
    20821 ccgaacgata ggattattat aaagtgtctt catcataaca aatttcctca cattttcttt
    20881 attctaatta cattccaaga gtatttttct atccctacat ttaattcgtc atgtttttct
    20941 attgaaaaat agtttatttc aggttttatt ttttctggtt cttcacgtgt atttttgtcc
    21001 aacagatcgc tactggttaa tgtgtagtgc tctccttgat ctagcaaatt gaaatcatgt
    21061 tcaatcgtta tcttttgttg ttcatttgtg cgattgatca agaaaatagt cagctgattg
    21121 ccgttatcta cgatcacact gtccacataa ggaacatttt ttatcttttc acaatcataa
    21181 acagggcaaa tgatttgttg tttcaatact tgacctttag catatttcga taagtgttgc
    21241 atcacataat aagttggatt cctccatgct tgtcctttag catctgtcag tattaaaggt
    21301 attgtgttta ctaacaatga ttgacaacta atctttacgc gatctgcgtg tcgtaaaata
    21361 gccagcccta atgaaccaaa taataatgta tcttccatag taaagtaaca ccaatcgatg
    21421 ggactaccga cttcaaaatc cctatgtctt ttttccggtt gggcatgtac attccattca
    21481 tcaaacgcta gatacattgt tttctcactt ctcaaatatc cttttacata atcacaagta
    21541 gcaacgattt cttcaatttg acgatcgaat cgataagctt ttgcaaggta tgtcgctgta
    21601 tcatcacgct catttttagg aggtttagtc aagtcttctt catcatactt atcaatatag
    21661 ttatgcaaag ctaaataatc tacattctca taagcttctt ctaatgcgat acgatcccat
    21721 tcagggtacg atggtaaacg tggcgtagag cttccaacta agattgtttc aattgaatca
    21781 tccactaact tcatgacttt tgaggcttca tttgctaacc taccatattc ataagcactc
    21841 ttagccccca cttgccatgg accgtctagc tcattcccta aacaccataa tttaacgcca
    21901 aaaggctttt tttgcccatt ttttattctt aaatcactcc agaaggttcc ttttggaaaa
    21961 ttacaatatt ctactaaatt ttttgcttca tcaattcctt ttgttcctaa attcaccgtg
    22021 aatatcggtt tcgcttgtac atgactgatc catttaaaaa attcgtggag tccaaaagaa
    22081 tttggttcta tacctcgcca tgctaaatca attttttttg gtcgttgttc tttcctacct
    22141 acagtatcca cccaatcata accagatgta aagtttcctc caggatagcg aatgacacct
    22201 aattctaatt cctttacata agagaggaca tcttgtctaa acccgtcacc atcagctgtt
    22261 tcatggcccg gttcataaat ccctgtatag acgacacttc ccatatgctc aacaaatgag
    22321 ccaaacagcc gagaactgat ctctcctacc gtaaaatcct ctctgatttt tactttcact
    22381 tcttcgtcca acagctttcc ctacctttca tttcctatag tcaagataat agatacaagt
    22441 ttccatacgc caccagcaaa gataaaaata aaaggaggga aaagaaatat gagcagtaca
    22501 aatcctaata acaatacgca acaaagaata tttctcaaaa aatcaaaaaa tactttccat
    22561 gcactttgtt caaaaatttg taaaaatgtg atatctttgt tttcagaaat cacatatatc
    22621 caggataaaa gaaacatgga ataaataagt aaaactacat atccactaat tgaaagtacg
    22681 attgtctgtt cttctaataa ttgattaaca agaaaataaa taatgatcgt taacagacta
    22741 aggaacaagt tcttaccaaa atgttgcttt attccttgaa agaaaaaata aatgatattt
    22801 cctgatccct cacctttcca ttgcgccatt acataaaaaa cagcacatgt agcaggcacg
    22861 atagtaataa caggcaaaca cacgattacc cagagaatac ctaataagat gtaatcagaa
    22921 accacaatca actgtccata aagtttagtc tcaactattt tcatcttcct cactctttca
    22981 ttccagacat agctgttcct tgaacaaaat atttctgtgc aaaaatataa accactagta
    23041 atggcagcat tgaaataacc gttccagcca ttacaggtcc ataaaaagaa atgttctgcc
    23101 ctgtaaataa agctaaccct gctggtaaag ttctcatttt tgaactactt gtcaatatca
    23161 atggataaag caagtcattc caactattca tcagcgtgaa aatccctaat gataaaagag
    23221 taggtttgct caatggcaac atgattttca aaaaaatatt aaactcactt aatccatcaa
    23281 tgcgtgctgc ctcttccaaa gaatctggta aagtaataaa aaaggaacgc atcatgaaga
    23341 taccaaatgc agttgtcata cgaggaatga tcaaacctgc ataagtatca agcatgccaa
    23401 gcaaattgac ttcaataaat agaggaatca tgaagacttg gaatgggatc atcattgtca
    23461 gcaaaacgaa atagaacaaa actgattttc ctttgaaacg catacgagca aatgcatacc
    23521 ccgcaagaga atcaaagaat acagaagtga tcactgtccc tccagcaaaa atcactgtat
    23581 ttttgatgta atctaataaa gggatcgttg tccaaacctt aatatagtta tctagggtat
    23641 agctatctgc aaatattcta ggcggaaatg agataatgtc tttttcgtgt ttaaaagaag
    23701 aaataatcag ccacaaaaaa ggaaacgcaa taaccaacaa tataactagc atactaatcg
    23761 ttcgaatgat ttttttacca ctaactgctt ttcgactatt cacagtaact gtaatcgagc
    23821 tttctggtgc catacaggtt tccctcctat ttcatttgtt tttctttccg tgacatgtac
    23881 acattagtgg agatagctat agttgcaaca atgataaaca aaaccgaaga cagtgctgat
    23941 gcatagccca attcataagg tgctgtaaat cctcgactgt aaatatattg aacagctgtt
    24001 tctgtcttaa attgtgggcc accagcggtt gcaacatata cttggtcaaa cacttgcatc
    24061 gaaccaatca gattcgttaa aatacaaaaa cctaaggagg gaacgatctg aggtagcgta
    24121 atgttaaaaa actgctgtcg atttgttgca ccatccattt gagcagattc atacaaagag
    24181 ggagagattc cctgaatagc agtcaagaga atcgtcatag taacaccaaa attcttccaa
    24241 acagtcatga tggctaccgt cggcatagca agggttggat cgcgaaaaaa ttgagggatc
    24301 ggcaagccga cttgtgaaaa caagtaagga atcgccccta cattcggatc aagcaacata
    24361 gaaaaaataa tcgcaattga cgtcaatgaa caaataactg gaatgtaaaa tgtcgaacga
    24421 caaaaacgat tgaatctggt atttttagat aatgctactg ctgctaataa accaacgata
    24481 atttgtgttg gcgtttcgag tacggtgaaa tataaagaat gaatcaacga attaactgct
    24541 cgttcatcac taaatatacg tgtgaaattt tcaaaactta caaaatttct tgatgtaaag
    24601 aaaatattca aatctgtaaa actaatagca aatgttccta aaagcggtat gacagtaaat
    24661 aataataaaa ctaaaaaaga tggagttaaa aacaaatacg cagcacgatc aggacgattc
    24721 caatatttgg tgaatccgtt catatagtcc acctcatctt tcattttgat aaaatataca
    24781 atcttggttt aaacgaatct gaataagata tccgaacaat cgctgtgatt tttgcaataa
    24841 cacctatctg caaatactag gtcgatcatt cagatatctg tatcttgcca acagtctatc
    24901 ctgtataaag ttctgtacta tttttgcagt aattgattga tggcatcatc tgcatcgttc
    24961 atgagtgtct caggatcttc tcctgctaat aatttttcaa tcagtggatt gatgatatcg
    25021 ttattgatcg cagagatttg ggtaaaacct ggtaaatatg gctctgcata gtccatttgt
    25081 ttcgataatt cagatacaat aggatcattt tttacttctt catcttttgc tactgaatcc
    25141 aagtaggcag gaaaaccatt ttcgatactc cattttttac caatttcagt tgtattccaa
    25201 tatttcaaaa actcatagac agcttctttt ttattattat ctgtacttgc cggaatggca
    25261 tatcctacgc catctaaaat agctgttttt ttgtctgaat cactcccttg tggtaaggta
    25321 gtcacattat aatcaatctc gtttgctttc aatccgttat ttaaccatgg cccattgatt
    25381 tcaatggcta gttgaccagc attcattaaa ttgtccattt cggcgccaga aatcgattct
    25441 ggaccagtct tgtctacatg gatcattttt tggatcgctt ttaacgtttt aaggttctca
    25501 ggagacgcaa attcagactt agtataatca tcgttcacta atttaccgcc atttgctaac
    25561 atccagttat ataacggtgc agttccatcc ttattgaaga caaaacctga tacattttta
    25621 ctactatcag ttaattttgg tgccatttct gtcaattctt cccaagtagt aggtggttgt
    25681 tcagtatcta atccagcttg tttaaacaaa tcattattcc aatacatata catgccttgt
    25741 acctgcatgg ggacaaaata ctgtttacct tctacttcac ctaattcaat agccgtttct
    25801 ttaaaatcag atttatctac tccatcatat tcccagaaat cgtctaatgg ttgtaccgct
    25861 ccgttttcta catactgtgc aaaatctgga taatttaatg caataaagtc aggtgctttt
    25921 ttagaagaaa tcgctgtagg aagtttttca ttcaaattgg cccaagtcat gatatccatt
    25981 tcaattttga tgtttttatc atttgtttta ttaaattcat taacgatttc ttgcaatatt
    26041 tcaccatcag atgcagtaaa cccattccaa aaagtcaaag tcacttcttt atcagaatca
    26101 gattctgctg aacttccgcc accgcaagct cctaaaatac ctgttgcagc taccaacaaa
    26161 gagccaatta accatttttt acctttcatt ttttgttcct ccttcatctg ataaacgaca
    26221 tctgaccaca ttccaagata gcggtttcaa taaacaattg attttcccat cttcagcttt
    26281 tacatttgtt gaatgacttg gttttacttg ttcactttta ggaagattag ttgcttttgt
    26341 atcaaatcca ctcatttcag aaaaatcaat cactccctct aatgataatt cagacaagtg
    26401 aacagttaga ttcatttctt cttctccacg gttaactgca aatatgacaa gttctttgtc
    26461 atttattacg gctatacttt ctaaatacgg cacttcttca aaatcttccg tcgcatagtt
    26521 tgctgaacga atttgtgggc ttaacacctc tccttgtcca tacacagcag cttgcataaa
    26581 tggataatag atcgtctgtc tccaagcttc tccgtttgtt tctgtcctga ttggtgcaat
    26641 aacatttacc aattgagcaa gacaagcaat ctttactcta tctgcatgtt tcaataaagt
    26701 gattaataga cagcctaata gtaatgcatc ttcaaaatta tagttatctt ctagtaaagg
    26761 aggagcaatc tgccaaggcg ctgcttgctc atcttgttcc gctgaatgat accaaatatt
    26821 ccattcatca aaggacaggt tgatctgctt cttactatgt ttcttcgcct tgactgtatc
    26881 gcacatcgct gtcacttcag aaatgaaccg atccatgtct aaggaacgtg caagataatg
    26941 agaaagatca tttttttggt tgccataata ttgatgcaga gacaaataat ctatttgatc
    27001 gtacgcttga tcaagaactg ttaactccca atcaccaaat gtaggcattt gccgattcga
    27061 acttccgcat aaaaccacct caattgaatc atctacgagt ttcatcgcct tagccgtttc
    27121 ctctgctaac cgtccatatt cttccgctgt tttatgtcca atctgccaag gaccgtccat
    27181 ttcattccct aaacaccatg tcttaattcc aaaagggctc tcttgaccat tcgaacgcct
    27241 taaatcactc caataagttc ctttaggaaa attacaatat tcgactaaat tacgagctgc
    27301 atctactcca cgagtaccca gattgacagc catattgatt tcggccccca catgctgaca
    27361 ccagttataa aattcatgaa tcccaacttc attcgtttca attgtccgcc aagctaaatc
    27421 caaccttcta ggtctatttg ctatgggccc aatactgtct tcccaacgaa atcctgacac
    27481 aaaatttcca ccaggatatc taatcatggg aatgttcaat tcttttacca agtgaatgac
    27541 gtcttggcga aatccacttt tattagctga tggatgatct ggctgataaa tcccttcata
    27601 tactgctcgt cccatatgtt caataaatga actgtacaac cgcggatcaa ctttgcctac
    27661 acgcttgaca ctactaatca acattgtggc ttccataact gacctccttt aatttataca
    27721 tgaataatac acctcgttga aagcgttgtc aataatataa atgttaaact tacttatttt
    27781 ttatcgattt taattaacca aaatattaat aatgattaaa acaaataatt taatataact
    27841 tttattaaca aatatgttaa tatataagaa aaacctttta agaggtgata tatatgcaac
    27901 tacaaataaa cgaagaatcc ttaccggtat atgaagcatt agctagtaaa acaaggatca
    27961 agatcatcca gctactttcc aaaaaaaaga tgaatgtcaa agatttggca aaagaacttg
    28021 gagtgagcag tgctatcacg acgatgcacg tgaaaaagct agaggaagca aacatcatca
    28081 aaacagaaaa agtaggacaa caaaaaattt cgagccttcg tgtcgataaa atcgatatca
    28141 gttttccaga aaaaatattc aatgcttttg atacgaaaga aacatcgata cctattggtc
    28201 actatacaaa ttatgcaatt gaaccaacat gcggtttagc tacgatccat gattttatcg
    28261 ggaaagtgga tgaaccacgc tattttatgg atcctcgaag gatggatgcc cgcattctct
    28321 ggtttaccag cggatttgtc gagtatcagg cacctaattt tttaaataca gaggatacat
    28381 tggagatgtt ggaagtttct gtggaaattt cttctgaatt tcctttttca aatgacaatt
    28441 ggccttcaga tatcactttc agcctaaatg gtgtggagct aggaacatgg acgagccctg
    28501 gagattttgc tgatatccgc ggtaaatata cgcctgattg gtatccagat aatcttaatc
    28561 aatacggctt gctgaagacg atccgaatta ccaaacactt gacgaatatg aatggagaac
    28621 ccttgtcaaa catcacgatc aacgacatcc ctaaagagca agacacttgg catttgcgaa
    28681 tcgaagtgaa agacgatgcc aaacatgtgg ggggctgtac tttatttggt aaaggattcg
    28741 gtaattacga tcaggatatc aaattaaaag tttactacag ctgatatttt tcttttctat
    28801 tttataaaac aaaaacagcc aatccctatg aagggacggc tgtttttgct ttattgttat
    28861 ttccagaaat catccaaaac ggaaattggc aaatgtcgtt tatgttgtgt cttgttccac
    28921 catgcttcga ttttttcttg tgcttgagcg ggaacttctt ttccttctag ataatcatca
    28981 atttcattat atgtgacacc tagtgcgact tcatctgcaa tcattggttt cccatcttca
    29041 agatctgcag tcggaatttt tgtgtataat ttttccggtg cattcaatgc ttgaagcaat
    29101 tgtttccctt gtcgtttgtc caaacggaat aatggcaaaa tgtcggctcc accatcacca
    29161 aatttcgtga agaatccagt aatgttttct gcagcatgat ctgtccctaa tacggctcct
    29221 gctctttctc cagctacggc atattgcgta atcatacgtt gacgtgcttt gatatttcct
    29281 ttgttaaaat cgctgattcc cacacctgct tcgcttaata cttgtacttg tgcatcaaca
    29341 gctggtttga tatttactcg cagactaaca tcgggctgga taaagtcaag agcagctttt
    29401 gcatcttctt catctgcttg ttcaccataa ggaagacgaa cagcgataaa ttgatagttt
    29461 tcatcttttg tttcttcacg catttcttcc atcgttagtt gcgccaaacg gcctgctaaa
    29521 gtagaatctt ggccgccgct gatacctagt acaaaagttt taagaaacgg atattttttc
    29581 aaatatgctt tcataaagtc aatactttta cgtatttctt cttttggatc aattgttggt
    29641 ttgacaccta attcattgat aatttctgtc tgcaggctca tttattctcc tcctatgctt
    29701 ctgtatgaag ttctgctacg ctttttttca ttcgttccat gatagccatt ttatggttcc
    29761 agcattcagt agacagatcg actgggtatt tttgcggatt caagtctcgt ttatactctt
    29821 cccatagtga atctagattt tcttttgtat attctttgat ttcgtttagt gcaggtaatt
    29881 cgtaaactct ttttccttcg ataaagatat cttgtaaaac tgggcgagct gtaaagtctc
    29941 gaacagtttt attgataaac gtatgcactg gatggaacat gaagatagct tcttcttctc
    30001 gagggtcttc atcccataat gtcacgtagt ctccttcaga tttcccatca aaatttcgag
    30061 tgatgcgcca cacttgtttt ttccctggag tagttacttt ttctgcattg cttgataact
    30121 tgatcgtatc catcattttt ccttcatcat cttcgatcga tactagcttg aatactgcac
    30181 caagggctgg ctgatcatag gctgtgatca attttgtccc aacaccccat acatcaattt
    30241 tagctttttg catctttaaa ttcaaaatcg ttgcttcatc caagtcattc gaagcataga
    30301 tttttgcttc cgtaaatccg gctgcatcta attgttcccg aacacgctta gatatatagg
    30361 ccatatctcc actgtcgatg cgtacgcctt ggaagttgat tttgtcacct aattctttcg
    30421 ccacgcgaat cgcacttggc acacctgatt tcaacgtatc ataagtgtcg actaagaaca
    30481 cgcagtcttt atgggtttta gcgtaggcca taaatgcttc ataatcattt ccataagatt
    30541 ggactaacga atgagcatgg gtcccgctag ctggtatccc aaatatcttc ccagcacgta
    30601 cattgcttgt tgcatctgct ccgccgatat atgccgctct agttccccag actgctgcat
    30661 ccagttcttg tgcccgtcta gttccaaatt ccaatagtgg atcttctccg atgacagatt
    30721 tgatacgagc tgcttttgtc gcgatcaacg tttggaaatt gaccatattc aacagtgctg
    30781 tttctactaa ttggcagtgc gctaaaggcc cttccacttg gattaatggt tcatttgcaa
    30841 aaactagttc tccttcacga gcagaacgaa ctgttgcttt aaattcaaaa ttttgtaaat
    30901 actccaaaaa accttcagga tagacttcta atccacgcaa gtaagcaata tcggaatcat
    30961 tgaacgtcag attctctaaa taattgacta accgttccaa tcctgcaaaa accgcgtatc
    31021 cgtggttaaa aggcatttct cgaaagtaac attcaaaaac agcatgtaaa tcagctcgac
    31081 ctaattccca gtatgtctgc atcatattga tttgatatag atccgtatgc agcgtcaaac
    31141 tgtcgtctgg gtaagtatta ttcatcttgt attactcctc ttggcaagtt ttcatttcct
    31201 acccattata acaaaaaaaa ttaataggaa aagaaatctt ccattttttc tgaaaaagca
    31261 catgttttac ggatatttct tgctaaaaat gaactccatc tgctaaaact atcctttctt
    31321 attggtattt aacctaaacg agaaagaata cttattttat tcaatgtatc cgagacacga
    31381 agaaattagc gttttctatt tttcttactt gataaaataa gtagattttc ctactacaat
    31441 cgtagccgtt aagataccga tgattgaaca aatataacca aatgtctcta caacataatc
    31501 aatggcaaaa gtttttgaag caataatacg tctttccttt tttgcttctt atccccaaag
    31561 aaacggatat aacttattat gtattgaatt tttttggaaa ggcgaattat gacaagatat
    31621 accttgcgtt gaaaaaactc gcggaaaaaa tatcacacgt ttttaaaaag atacaaagta
    31681 agaaagcagc tgtcaataga atggaaacaa aaatggcgag acatcaatca gtctcgcctt
    31741 gttttttatt gtatacatta gatatggagc aggttaccat aaagatgatt attagtcgtt
    31801 attaaataga atccttcgta tttttttgtt ctatcactac aatatcttta tttggacgtt
    31861 tgaattgtat tccggcacgt tctagctcct gtttcactcc tacatggact ttgacatctt
    31921 ctcgtgtcat ttttaaaacg tgatgaatcg catagtcgat ttcttgcctt gtgatttttt
    31981 tcttcgtatt gatcatcacg acttgctttt tatcatatgt gtctaccaat agcagttgtg
    32041 ttcgatctaa cgaaaataat ttgtaataat taatagccgt attcccaaaa aagaattcca
    32101 ctactttagg ataaaatgtc ttaatattta aattactatt cacaggtgtt tcgattagct
    32161 tcatctcatt cctcttttct atatagtcga tttagatcca atcttaagtt atgttaccat
    32221 ctttcctagc attaaggaat cggttacaat tgaaccttta aagacaaaag gatttacctt
    32281 ttatcactta atagtataac ataatttcgt gagaaaaaaa tacaattttt tcttgaccat
    32341 ctcgttacgt aaaggattat gcttacattt gtcaggagga aaaataatgg agtacacaat
    32401 aaagaaaatg tcagagatat caggagtcag tccgagaacc ttgcgctttt atgatgagat
    32461 tggactgcta aaaccagcta ggatcaattc ttcaggttat cggatttatg gcaaaaaaga
    32521 agtcgatcgt ctgcaacaca tcttatttta tcgaacaatg gcattcaagt tggatgatat
    32581 ccaagaggtc ttagacaatc catcttttga ccaccagaaa gctttaatca agcatcagca
    32641 aatgttgctg gaaaaacggg cacaaatcga taccctcttg acaactgtcc aacagacact
    32701 tgatatgtac gaaggaggaa gaaaaatgag tgacaaagaa aaatttgaag ggtttaaaca
    32761 acaaaagttg aaagaaaatg aagaatccta tggacaagag attcgacaaa aatacggaaa
    32821 aaaaaaggtt acagcatcca atgaaaaatg gatgaatatg gataaagaaa cgtatgaaga
    32881 aatgcaaact gttgaaaagc agatgttatt tgatctcact ctttacttaa aagaaccaga
    32941 agatgaaagc ttagcagacc gtatcttcca agctcataag aagtggttct cttacagctg
    33001 gcctgaatat cagccaaaag cgcataaagg actaggaatg atgtacgaag ccgatgaacg
    33061 gttcactgca tattatgacg agcgaagtgg tcatggtgca gcaaaagctt taaatgaaat
    33121 tatccaaaaa aaggcgtaat cttttacatg atccaacaaa aaagtacacg taaaatgacc
    33181 taataacaaa acagcagaca cccaagttag atttttatgc taacttttgg tgtctgctcc
    33241 attctttcac aagttttttc atcctacttt aaatatattc atcgttgaat aaacgtataa
    33301 ggtattttca ctttatcctt tttttctgta agaaacaatt gaaatgccat ttctccgcaa
    33361 gcttccagat ggtggtcgat ggttgggaaa ccaagaagct cgctgatcag caaattatcg
    33421 cgtccaatca ccactggtgt cttatcttgc agatagcttt gcaagatgcc tgctgcaacc
    33481 atatccgaat ttgtaaagac accatcaact ccaagctctt taaaaaagaa gcctgcttgt
    33541 tttcctttct ctgcatctat acaatcccaa aaaacaagtg attcatcaaa agatggaaaa
    33601 agttgatgac atagctgcaa agtgattttt gagttataac ttagcctgcc acttcgcccc
    33661 aacgtgatgc ccaattgctt tataccttgc tgcttcaaat aagtaagacc ttctgtaatt
    33721 gattgttctc gatcaataaa gacacagctt gcctgttttc ccttgatttc ttcacaaaaa
    33781 actagaggtc catatttttg atatgccaat aaatcatcta gtgtattggc acgagacgta
    33841 atgatcaatc catcgaaagc tttagctgca aattcttcaa gataccttcg ctctttttct
    33901 ttatgatagc ccgtcggtaa aagtgtcact ttgtaatcat aatcaaacgc tgcttcaatg
    33961 atcccactga tcaactgatc aaaatacgga tgattggtat aaggcagaat cactccaatg
    34021 cttttcgttt ttccataact taactgtctg gcatttgcat tagggatata atcgacttct
    34081 ttcatgaccg caagtatttc tttccttttt tcctcatcta catatggatg tccattgatt
    34141 acacgtgaaa tagtagaaac tgaataacct gtgagctttg cgatatctcg aatgtttgcc
    34201 actgctgctt cgccacctat acaaaaagat tttcttgtaa atagtctacc acagctggac
    34261 cgcattcaaa aaactgatac atttttcctt catgcgaaaa actgatccgc tgcccgcccc
    34321 aatatatatc ttttgtcaaa ttttcgattt cattcattgg tatttctttt actatattcc
    34381 tattcaaccc ttgaaaactg tacaacgtta atacggatcc cttgaactcg acaaacgcat
    34441 aaaaataatt gttcgttgtg ccatctgtta tctctacata agtattcatt gcaagccctc
    34501 cttttgatac tttgagtata gtgtatgaaa cgcgtctcat agcaaggagt ttgttttgcc
    34561 aaagaaaagt tttattcctc tttcattatt accaaagtct cttattttaa attgaataca
    34621 ttataatgat actgtaaata tatctttatt attagtgaat
//
LOCUS       DBGZHO010000023        34653 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.023, whole genome shotgun sequence.
ACCESSION   DBGZHO010000023 DBGZHO010000000
VERSION     DBGZHO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.023"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(59..1612)
                     /locus_tag="ACN3HL_001323"
     CDS             complement(59..1612)
                     /locus_tag="ACN3HL_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006211.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            1760..3049
                     /locus_tag="ACN3HL_001324"
     CDS             1760..3049
                     /locus_tag="ACN3HL_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HHC8006212.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(3175..4254)
                     /locus_tag="ACN3HL_001325"
     CDS             complement(3175..4254)
                     /locus_tag="ACN3HL_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHC8006213.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(4363..4803)
                     /locus_tag="ACN3HL_001326"
     CDS             complement(4363..4803)
                     /locus_tag="ACN3HL_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHC8006214.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4860..5270)
                     /locus_tag="ACN3HL_001327"
     CDS             complement(4860..5270)
                     /locus_tag="ACN3HL_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HHC8006215.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5451..5885)
                     /locus_tag="ACN3HL_001328"
     CDS             complement(5451..5885)
                     /locus_tag="ACN3HL_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8006216.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(5985..6833)
                     /locus_tag="ACN3HL_001329"
     CDS             complement(5985..6833)
                     /locus_tag="ACN3HL_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8006217.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            7222..8988
                     /locus_tag="ACN3HL_001330"
     CDS             7222..8988
                     /locus_tag="ACN3HL_001330"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HHC8006218.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            9090..10349
                     /locus_tag="ACN3HL_001331"
     CDS             9090..10349
                     /locus_tag="ACN3HL_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHC8006219.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10496..11797
                     /locus_tag="ACN3HL_001332"
     CDS             10496..11797
                     /locus_tag="ACN3HL_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006220.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11800..12651
                     /locus_tag="ACN3HL_001333"
     CDS             11800..12651
                     /locus_tag="ACN3HL_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HHC8006221.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12664..13479
                     /locus_tag="ACN3HL_001334"
     CDS             12664..13479
                     /locus_tag="ACN3HL_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HHC8006222.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            13630..14796
                     /locus_tag="ACN3HL_001335"
     CDS             13630..14796
                     /locus_tag="ACN3HL_001335"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8006223.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            15026..15673
                     /locus_tag="ACN3HL_001336"
     CDS             15026..15673
                     /locus_tag="ACN3HL_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HHC8006224.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            15757..16701
                     /locus_tag="ACN3HL_001337"
     CDS             15757..16701
                     /locus_tag="ACN3HL_001337"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HHC8006225.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            16836..18287
                     /locus_tag="ACN3HL_001338"
     CDS             16836..18287
                     /locus_tag="ACN3HL_001338"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HHC8006226.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            18308..19144
                     /locus_tag="ACN3HL_001339"
     CDS             18308..19144
                     /locus_tag="ACN3HL_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HHC8006227.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            19144..19803
                     /locus_tag="ACN3HL_001340"
     CDS             19144..19803
                     /locus_tag="ACN3HL_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHC8006228.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            19929..20618
                     /locus_tag="ACN3HL_001341"
     CDS             19929..20618
                     /locus_tag="ACN3HL_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006229.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            20624..21580
                     /locus_tag="ACN3HL_001342"
     CDS             20624..21580
                     /locus_tag="ACN3HL_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HHC8006230.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            21624..22136
                     /locus_tag="ACN3HL_001343"
     CDS             21624..22136
                     /locus_tag="ACN3HL_001343"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006231.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(22392..22940)
                     /locus_tag="ACN3HL_001344"
     CDS             complement(22392..22940)
                     /locus_tag="ACN3HL_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HHC8006232.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(23029..24210)
                     /locus_tag="ACN3HL_001345"
     CDS             complement(23029..24210)
                     /locus_tag="ACN3HL_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HHC8006233.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(24446..25954)
                     /locus_tag="ACN3HL_001346"
     CDS             complement(24446..25954)
                     /locus_tag="ACN3HL_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HHC8006234.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            26113..26304
                     /locus_tag="ACN3HL_001347"
     CDS             26113..26304
                     /locus_tag="ACN3HL_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006235.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            26507..27424
                     /locus_tag="ACN3HL_001348"
     CDS             26507..27424
                     /locus_tag="ACN3HL_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HHC8006236.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            27417..28490
                     /locus_tag="ACN3HL_001349"
     CDS             27417..28490
                     /locus_tag="ACN3HL_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006237.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            28638..29156
                     /locus_tag="ACN3HL_001350"
     CDS             28638..29156
                     /locus_tag="ACN3HL_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006238.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            29137..29529
                     /locus_tag="ACN3HL_001351"
     CDS             29137..29529
                     /locus_tag="ACN3HL_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HHC8006239.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            29605..30540
                     /locus_tag="ACN3HL_001352"
     CDS             29605..30540
                     /locus_tag="ACN3HL_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHC8006240.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            30673..31452
                     /locus_tag="ACN3HL_001353"
     CDS             30673..31452
                     /locus_tag="ACN3HL_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HHC8006241.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            31445..31762
                     /locus_tag="ACN3HL_001354"
     CDS             31445..31762
                     /locus_tag="ACN3HL_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HHC8006242.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            32006..33616
                     /locus_tag="ACN3HL_001355"
     CDS             32006..33616
                     /locus_tag="ACN3HL_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HHC8006243.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            33773..34621
                     /locus_tag="ACN3HL_001356"
     CDS             33773..34621
                     /locus_tag="ACN3HL_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHC8006244.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        11456 a         6166 c         6707 g        10324 t
ORIGIN      
        1 ttgatacata aatccggagg ttgttaataa gcattcggat ttatgtatct tatttggtct
       61 aggaagtaac ttgattttct tttttcgatt gatccatgag tgcttcttct tttaattcaa
      121 agatatattc tgagatcctc ataatcactt ttttccagtc ttctggtgtg atgattcctt
      181 ttaaaatata gatttttttg atatgagaag gcaattgttt caaagggcag tcgctgataa
      241 cgatgttgca gttctccata aaatcatttt gtattttgat cgattcattt gaaaaaattt
      301 gttctatctt aacgatcaga tctttactga tataaaaatc acgcgtatag ttcacaccaa
      361 tcacaattcg cggctgtttt ttgtagcgat catacaaatg tactaggtct tcaaccatcc
      421 attgcacatt ttccttttct aaaataactg gtaacaagtg ttgattttgt tctctgaaat
      481 ccatataaaa ttgttcaatg gcggtttgga cttctttcaa cacgctatgt tcttgataaa
      541 gcatgaaagt aggaaggggc gtatttggtt gattgaagtt aagaaatcca ttataaagtt
      601 tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt ttcaggtata aacaaatcaa
      661 atacagtaca aaaggactcc accatttctc ttgaataaag aacatgagga acgtttgctt
      721 tttttaaaag tttgtattgc tccaagcttg tttcttccga ttcgattttc gtgatagaaa
      781 gtcgagctaa aatattcact aagatgcgtt gttcgcgaca aattggcaga ttaggtcgca
      841 aaatatctac agagggatca ataaaaaagt caatatattc atactctgtg aattcttttt
      901 gtacgtcttt cacagaagtt gcaggaaaat tctctttaca tatttttaat agaaaatata
      961 atttatctat cataccgcta tttagtcggt caagtacttc ttttttaaaa aaagtattca
     1021 tcataaaagc cactacttgc ggatcttcat cataaaattc tgtagcagta cttgaaaaga
     1081 tgttccaata aatatctaat gctgcatatt gaatttgtac ctcttttcca gaaaaagact
     1141 ttctgccatt attagaaaag gagatagaca aaccgtacaa tgctaaaaat gcattaatct
     1201 ttttcatttt cgtatacaaa taagaggcac tatagtttgt ttgctgactt aaactgataa
     1261 tcgaatttgt ctgacagctg aacaaagaag tcaagatctg ataactgact gattcgttgc
     1321 agtatcttcc aaatagacga taatagcagt aagccggatc aattccttca aaattcaact
     1381 ttaaaaaagg tttttgctta tcaatatgca gttctgttag attgagacgc tcaaagtctt
     1441 gttctaattc tttgatgtat agtaaaaaat ttgattcaga catatggaaa tgatctgcta
     1501 aatattgtgt agtaataaag aaacgatgtt cagataggaa aagaaaaata tctaattttg
     1561 tattgctttt tttcttcaag agaaacgttt taatcgcttc ttgagtttgc atgaaagagg
     1621 ctccttttta cttaaattgt taaaacttga aaatattact gtttttttca taaatttaga
     1681 caaaaaaaca gtaaacatat aggtagaatc tctactatct tatttcttgc atacaaaaaa
     1741 atcaaggagt gagagagtta tgagatattc aaccatctta atatcaacat ttgcagcctt
     1801 aagcttatcg cttactataa atcagacagt ccacacagag gagatagaaa cagccaaatg
     1861 gacagaaacc aagtgggcca acgtcaatcg aattaccttt caggatgaat tttcatcctt
     1921 caattcagga gtcgcaaaat taagaaaagg acaaacagcg accatcaaag caaaaattga
     1981 ctattcagga gacttagcac ctatactaca atcagctgtt acatttgaga atgttgatcc
     2041 cgctttgtcg attggctatg acgagaacac tttgactatc caacacaagc aagcgatatt
     2101 taccttcacc gttacattaa atcaggactt gttaaaacca gcgcttttta ctgtcaaggt
     2161 atcagatgga ctaccgaacg atcatcatca tttaacgccg tatagtcagc ggcagacaat
     2221 tgagcaagat tcagctatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc
     2281 agaaaatgaa aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc
     2341 ggaaatagaa cctggagaag aacccgatac agaaactcaa ccagagccag acaatgaatc
     2401 aaaacctgaa ataacccctg gagaaaaacc agatgtagac ccagaagaaa aaccggatgt
     2461 gactccagaa ccagatacgg attctggaaa ccaaacagta ccggaaacaa atccagacac
     2521 agataatgaa actgaaaatc cagaaaaacc agaggcagcc ccagaagaaa aaccagatgt
     2581 aactccagaa ccagatacgg attctggaaa ccaaacagta ccggaaacaa atccagacac
     2641 agataatgaa actgaaaatc cagaaaaact agaggtagat ccagaagaaa aaccagatgt
     2701 gactccagaa ccagatacgg acgcaagaga ccaaggaata ccagaaaaaa taaacaaaaa
     2761 aacaattcaa gaggatggaa aaaaagagag taaaaaatca aatctagcaa ttctaaaaat
     2821 aaatgaagag cagctgaata aaaaatcacg aatatttgat agcgcccaat cagctgaaac
     2881 cttaaaaagt agcaaggata caacctttgc tagtcctgaa acgaaaaata aacagctacc
     2941 aaaatccgga gagtcacaaa acaaagttat actgtggagc ggaatcattc tattaagtat
     3001 agcaacaatg ctttctgcaa aaagatttaa acaaaacaga tctctctaac atttgaataa
     3061 tgtctgtgaa cgcatttttc aaataaaaag aaatatccag aaaacgaccc caaaatacca
     3121 gattgaaatc tgatatttgg ggtcgttcat actttatctt tcttcatatt tattttaagg
     3181 gatatctgtt tcttttggaa gatggttcgg gatctttttc actttcaata catctaaaaa
     3241 gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg ccaaagaacc gttcgctaac
     3301 aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt ttgctggaca tcaacttcgg
     3361 attcagcaca taagactcaa ttagatggac aatcaaaatc gtaatcagga tataaacaac
     3421 atctcggatg cctccttggg aataagctat gaaagataga ggaatacaag aaatgataac
     3481 acctgctact gggatcagac ttaaaatgaa aatcatgatc gctaaactca gcagctgatg
     3541 aaagccaaat acagccaagg cgattgtagt gagcaacgtg tttaaaagag cgataacaaa
     3601 ttgagcttct aataccaaac caaatgtatt gacaaactta tcggcaaaat agtaaatatc
     3661 ttgaaagaac caagaaaatt cactttttaa aaacaatctt gagaatacaa ttgttttttt
     3721 cttttcaatc ataaaaaaga aacttaagat gaatgacata gcaaacgcca ctgccatttt
     3781 tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca ttttgaagct gttcaaaaaa
     3841 atcgtttcgc tcaatataag tatggatata ttgtaaaaca ggatctgcat cttttggctg
     3901 atgctcgtaa aaatcaataa cggactggat catatcaaat gtttgatgaa taagcatcgg
     3961 gatatacttt gtgaatgcca gatagataag gtaaacgatc agtgtataaa tcatgatagc
     4021 taaaacacct gtagggattc ggacaaatcg ctgaatgatt tgaacaagat gaatcatcaa
     4081 ataagtaaag ataaatgtga gcaaaatggt tgtaatcata cttctaacta agaaaagaac
     4141 aaaaacgaca aataataaaa cagtgagacg gcgtattttt tcattcgcca aaaaacgctg
     4201 ataaacggtc aaatcgacaa cctccaaata acaaaaaata aacacgttat tcattatatg
     4261 atggaatatg aaaataagaa agagaaagag caaaaagaaa aaccgctaaa tgacgttatc
     4321 ttatgagttg gttttcctca taaaatcgtt catctagcag tttcagccct ttttctggtc
     4381 ttgatgaaaa ttatctagca tttttcgggt cagatgttgc agtgtatcca attcttcctg
     4441 ttcaagtgga agataagact tgatcttttg tggaatacct tctgcttgtt tttgcaacgc
     4501 agcaccttga ggagtcagcg taacatttac gattctttca tcacccgttt cacgctgacg
     4561 attaatataa tttttttctg ctaacttttt tagtaaggga gtcagcgtac cagaatccag
     4621 acacaaatca tttcctagct ctttcactga agtctttttc ttttcccata aaactaacat
     4681 cacaagatac tgggtatagg taagattcag cggcttgagg agggaagtgt agtgtctaat
     4741 gatttcctta gaggcggcat ataaaggaaa acatacttga ttaactaaat atagatcttc
     4801 catttttcca cctccgctgt tttactatag tgtatcatag cggatttaca caaaaaagtc
     4861 tattcactaa ctgctttcag agtaacttct atatttccag ctgtagcttt tgaatacgga
     4921 cacactttat gcgctgcctc taataattct tgcgtttctt ccagagaaag accttcgata
     4981 gatccttcaa tctctacacc taagacaaag ctcgtttcac tttctgaata aagggaaact
     5041 tgtgcactga cagtagaagc cccagagata tttttttgct gtttgatcaa ttctaatgca
     5101 ctgttaaaac atgcactgaa accagctgca aacaattgtt cagggttggt tgcattttcg
     5161 acgcgtttac caggagctgc aatattcaat tcgaatgtac gatcgggatt atgaacttct
     5221 ccagagcgtc cgcctgtgtt gatcattttc gtagaataca tttttttcat aaaattacca
     5281 cctttaatta tattttatac aattgaattt tacacaatat aattgtggaa agcaaagaaa
     5341 tggattggca taagataaat aagagaaagc acatgaaaca gacgcgcttt ctcgaatagc
     5401 aaacatatac aaaaaaatat cagagacaaa aactaatctc atcataaaca ttacatatat
     5461 ttctcaaaaa gttgttttct ttcttcaaaa cttacttcac gatggacctg atgaagcatc
     5521 cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc catcatttct
     5581 gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt gtcctcgata
     5641 tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg agcagtcaaa
     5701 ccaagagacg tgttttcatc cagcatatgg aatctcgtgc catacaaggt aaaaatgact
     5761 tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc aaagattgtt
     5821 tgatacagtt ctagtgcttt caaactatca tttaatacaa aatctatttc cgttccttta
     5881 tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt attataccag
     5941 ttaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc gattggatga
     6001 taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa ggcacttgga
     6061 tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac aacgatcaat
     6121 aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt aaggccacgt
     6181 ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact catgaccata
     6241 acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga agtgattgca
     6301 atagataaaa tagcataaag aaactcttct attccaaaaa caaacagatt aagagaaaca
     6361 acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata ttttttaaaa
     6421 atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa aatcgcaact
     6481 cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga agtaatcatt
     6541 gtttctggaa ctattgcaat gattaaagga aaaaacaagc ttccgaaaag tactttaaaa
     6601 aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt caacactaaa
     6661 ataactatag ctcggtcaaa tcctaaaaca gcttccagta atattcctag accgctgaca
     6721 cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc taatatgaag
     6781 agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt catttatcca
     6841 cttccttaat tcattaataa tactcttatc ttattataac ttacttttca ccttaagtta
     6901 actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc ttctagaata
     6961 tacttctacg ttaaaaactg ttaaaaaact tttactttag aaaattggag aaattgatcg
     7021 cttaagataa attcaggaca ctaaatagta caggaagtag attaaaactt ttaaaagttt
     7081 taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa actgttaccg
     7141 ataacatttt tgaaagcgtt gtcttttgtt tctctatcac ttatagtgat gacgtcatat
     7201 taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc ggaaagtgaa
     7261 tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag gaaaaatgat
     7321 atcaaaaaag tatatgtgct ttgtggagat ccatatacca taacaactga aaaatggtat
     7381 caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta ttgggaaatt
     7441 gaagtgacga gcgaaacaag gcgcttacag tatgcgttcc atgttgttgg ggaagataac
     7501 acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt gattactgaa
     7561 ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac tattccagaa
     7621 tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa cggggacaaa
     7681 gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg agaagacttc
     7741 ttcgggggag atttgcaagg tgtgagggat catttggatt acttgacgga ccttggcgtc
     7801 aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata cgatacgatt
     7861 gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa cttgattgat
     7921 gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca tatgggtgtc
     7981 cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta taaagactgg
     8041 ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc agaaactgct
     8101 gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact aaatacagca
     8161 aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa agaattcgat
     8221 attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg gaaaaaattc
     8281 agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat ttggcattcc
     8341 tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc attcacagat
     8401 tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt cagtggaatg
     8461 aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa cttattagat
     8521 tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt gatgaagtct
     8581 gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg gacagaaata
     8641 gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga gaaggaggaa
     8701 caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa acagttgtct
     8761 aagattattt ctgaaggttc tactcagtgg ctaatagtat atgatcgtga agataagctc
     8821 tatttcacac gggaactaga gggacagatc atctatgttt actttaatca gtcaaaagaa
     8881 ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca gttgttagaa
     8941 gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa actgttaccg
     9001 gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa gggtgtaaca
     9061 gcacgttgaa tacacaggag gaaatgaaga tgaaaaaaag aagtgtgaaa cagttgggtt
     9121 tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat ggtaactctt
     9181 cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat tctggatata
     9241 aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg aaaatcaagc
     9301 tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg cctgctggaa
     9361 agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga cagcaaggac
     9421 atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac aaagcccaag
     9481 tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt gttttgtact
     9541 ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag aatctatcca
     9601 aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt ttagctaaat
     9661 ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat gtatttggtg
     9721 atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta gaaggaatct
     9781 cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac ataaaaagtg
     9841 caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc attgacggtc
     9901 catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc aaaattccta
     9961 ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg gtagtcagca
    10021 attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg aatcaggaaa
    10081 atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa gctagggaaa
    10141 cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat gaaacagctc
    10201 aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa aacttgatgt
    10261 tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca gtaaaaacaa
    10321 tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt tttataaaaa
    10381 atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat cttgctcttg
    10441 ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca ttcagatgca
    10501 gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac ttattccagg
    10561 gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg ccatattcgt
    10621 cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat tggttacttt
    10681 gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca ctttgcaatt
    10741 catcattaca atcattttct tgatttttta cggtttgaat cttttagacg cttatcgagt
    10801 agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag tcatacataa
    10861 tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc tcatgatttt
    10921 tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt atgacttcaa
    10981 tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt ttagtatctt
    11041 ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg tgatttggac
    11101 tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg ttgctcacca
    11161 gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat gggcggtccc
    11221 agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag gtgccatcaa
    11281 tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg caatctcttg
    11341 gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct ggttaggatt
    11401 tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag acttatatga
    11461 agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca cgcttcctgc
    11521 tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt tcaataattt
    11581 ctccatgatc tatctgttta acaatggtgg tcccggaagc gtaggcggag gagctggttc
    11641 tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc cgcagtattc
    11701 tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt cattgctggt
    11761 atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt tcattcgagt
    11821 gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt aatactgtca
    11881 gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc aggaaatatt
    11941 gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac tcggctattc
    12001 agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt cctaacaatg
    12061 atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta tcgttttatc
    12121 ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac tatggcagca
    12181 ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta ctggttcttg
    12241 acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa aggatacttt
    12301 gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg gcatttcagg
    12361 atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca agcattatgg
    12421 gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg aacacctgaa
    12481 aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa ccaaagagtc
    12541 tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt attcttcttt
    12601 ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata ggagcagagt
    12661 atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac tcaagtgttt
    12721 gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt tttagtttcc
    12781 ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat tccattagaa
    12841 caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt ttctgaactt
    12901 gaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac ccctgaaatt
    12961 ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt tattgatttt
    13021 gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg ctatacgatg
    13081 aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt ccaacgattt
    13141 ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta tagtttaagt
    13201 cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc ctttttcttg
    13261 tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag tgcaaatttg
    13321 atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt tatccacttt
    13381 gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct tttatgggtt
    13441 tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc gatttatgcg
    13501 acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct gaaaaaatta
    13561 aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt ttttttaagg
    13621 aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc tttctcgctc
    13681 cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac ggacactcct
    13741 ccccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac aagtaacgct
    13801 tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg aagtatccaa
    13861 gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa agattatcta
    13921 aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga tatccatgcg
    13981 cattatgact taggtaacga cttttataaa ctttggctag atccaacttt gacttattct
    14041 tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa taaagtccat
    14101 catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat cggttgtggc
    14161 tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac tgggatcaca
    14221 ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca tttagaagat
    14281 aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt tgatcatatc
    14341 acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta tttcaaagtg
    14401 gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag ccgacaacaa
    14461 ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta tgtccctggt
    14521 gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga tttggaaagc
    14581 ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca tcaagtccaa
    14641 gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct atatttacaa
    14701 gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt gcttgttcaa
    14761 cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta ctgtttaaag
    14821 actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt tgtctaactt
    14881 ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata aaagtttggt
    14941 tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa tagaatacta
    15001 ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta gtttatttgc
    15061 agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg ggaatacgtc
    15121 ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag caagcacatc
    15181 ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata tcaaagtgtc
    15241 tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa ttactagttt
    15301 ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg atgatcaaaa
    15361 agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga atccagaaac
    15421 tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg atgttgataa
    15481 attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa gcggtacggc
    15541 aacagattgg gatttggata aagatttagg tactacttat tgggaagtca aagtaaaaga
    15601 cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac tgtcaactga
    15661 acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta gtcatgatac
    15721 actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac gacctttgcc
    15781 aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat gactacccag
    15841 gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag ctgtacgatc
    15901 aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg gagtatcaat
    15961 tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct tgcgtatgaa
    16021 aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat gagtgtccag
    16081 gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat cactgaatta
    16141 aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt tgaggccact
    16201 tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat caaattgcct
    16261 ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca gtttccattg
    16321 acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac agaacaagaa
    16381 gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta tatcaagccg
    16441 actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat ccaaatcatt
    16501 ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg tggcgcaagc
    16561 atgttacaga ttggtacaga gcttcataaa gaagggccgg aaattttttc tagaatcata
    16621 aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga atttaaaggc
    16681 aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc gtcttttttt
    16741 ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt tagacgaact
    16801 tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca gaattagcaa
    16861 aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata cagaaaaaaa
    16921 taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc gagagtaatt
    16981 cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc ccatttcctt
    17041 taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct cgtttatttg
    17101 aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg ataggtctag
    17161 ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca gacccagtca
    17221 tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga tcaagtggag
    17281 gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt gatggcggtg
    17341 gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct tcgcgaggga
    17401 cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt gatttcggct
    17461 tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt atccattccg
    17521 gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa aaacggttga
    17581 agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag gcagtacttg
    17641 ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca gagattcctt
    17701 acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc gcagaaacag
    17761 cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa gaagaacttg
    17821 aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct acttacatcg
    17881 attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat caagaatacg
    17941 atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa gatttgcaaa
    18001 gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta gaaggtttag
    18061 acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca cagttggcta
    18121 atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa aacatgcctc
    18181 taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa atcggctatc
    18241 tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag aaacaaggag
    18301 aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt ttattttaag
    18361 cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg tagaaaaaaa
    18421 gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt ataatgatca
    18481 aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac ggttaaatgt
    18541 caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt caaaaagaga
    18601 atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa aattctccct
    18661 ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag atgattcagg
    18721 aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca atactagcta
    18781 tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg ccacgaatga
    18841 tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg attattatct
    18901 gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg agaacgttta
    18961 tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc tgaaaaagaa
    19021 aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa tatctgaaaa
    19081 atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt cggtgagtga
    19141 gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc tttcgtactg
    19201 caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg aaatttggta
    19261 gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt atttattcgt
    19321 ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct gttatatttc
    19381 gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac gattaccagc
    19441 agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc aggtcagtgg
    19501 gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat cgttttgccg
    19561 caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct agtgaaaggt
    19621 acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa gatcataggc
    19681 ggtcggacat tcgattattt ttctctctat attttagttg cactgattta ttgggtcatt
    19741 tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatcca tcagtcaatc
    19801 tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt ttcttgtata
    19861 ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata tgttcggagg
    19921 tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac caatattgca
    19981 tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa ggaattgtag
    20041 atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc tatgagctga
    20101 aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga cattataatt
    20161 attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct acaggaatag
    20221 gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct ggtacatttc
    20281 tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct ttgacaaacc
    20341 gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag cgaggcgtaa
    20401 aatattttcc aaaagatcaa ttgtacaaag aattgaaaag acgttcagaa aatcaagatc
    20461 cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt caggcaatca
    20521 atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg aggcaacaac
    20581 agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact atccttattt
    20641 aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag gattgctctc
    20701 caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta aaaatgtgat
    20761 cgaattattt caaaaaaagc accatccaat cgctgtgatc caaaatcccc aagtaggaca
    20821 attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata gctctgtcgt
    20881 ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac ctccagcgtt
    20941 tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac agttggcagg
    21001 agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc tgcccgaaaa
    21061 caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt atgcagataa
    21121 aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat atattggatt
    21181 ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta gccgagcgct
    21241 tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac attttgtctc
    21301 tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag gagataaaat
    21361 gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa tgattgaatt
    21421 attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa agtggtcact
    21481 tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt ggcttaaata
    21541 ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg taaatgaaaa
    21601 aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa gaagtagaag
    21661 aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc tctcctcaat
    21721 ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa agaaaagaaa
    21781 gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc tcaggcgtgg
    21841 atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct tatttatcga
    21901 ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa ccgttcttag
    21961 aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc gatacttatc
    22021 cagctaatga accgatggaa aagaccatct attctgctgg attcacttat caagggatga
    22081 ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc aattgactat
    22141 aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat catatgatag
    22201 ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt ccgaaaatgc
    22261 ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc tgaaactccc
    22321 ttcatcgaga ggtcgtgaca tagcttttgt cacgatctct cggcttatcc tacgagtatt
    22381 attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc ttggaacgct
    22441 ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa ctgtgctaaa
    22501 tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc acgttttttc
    22561 aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac taccgtcccg
    22621 aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca atttcctact
    22681 gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc atattggtcc
    22741 cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga aacaaaataa
    22801 taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt aatgatcttt
    22861 tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga aggaccgata
    22921 aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt gaaaaagctt
    22981 tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatttt ataccagcaa
    23041 gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa ttttcaatcc
    23101 gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac cagaaatgat
    23161 cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg ctgttgtacg
    23221 ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt catttgtaac
    23281 cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga ttccgctgat
    23341 gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc cgaatatccc
    23401 gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca tagcagcaac
    23461 cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga aaaatgtctg
    23521 ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat agggatttac
    23581 aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga tcacatattt
    23641 agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag acatagccga
    23701 tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt ttatggaaat
    23761 aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt ccaatttgcc
    23821 catcccgttg attttactta atcctagacc aacagctttc ataaataatg gaagaatctt
    23881 gatatagcgt agaataccga taatagcaga aataaataca attggcatca atacggaaag
    23941 aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa caccttgccc
    24001 agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg ctgtaccaaa
    24061 agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca caattagtgg
    24121 tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta atgtgacaaa
    24181 taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa ttccgtttta
    24241 ttttacctgt tttgcaaata aaatactaat ctttagtgaa attttcatta cttttttaga
    24301 gtgaaacgca ttcattttcc attagaaaat aaagcgaaca aaataaaagg tttaaaaagt
    24361 gtaacgtctt agtaaagtct ataaaaaaac gaaactatcg attaagctaa tagtttcgtt
    24421 ttcaacattt ataagtaaac tttttctatt ggtaatatag attttcggaa gggtagacag
    24481 gtgcgcaggt aatatcgatt cctagttttt tcaatgtttg ttcatcattt ttattgacca
    24541 tcacagtaga gtgggcttgt gctccctcaa gttcagctag tttatcataa gcaacttgag
    24601 cgattggatt cgttactgca ctgattgata aagcgatcaa gacttcattg atgcttagtg
    24661 catccaaaga ggaatgaagt gtctttgatt tcaatccttg tattgtttca agaactaatg
    24721 gtgacaataa aggaatgtca tctgcgatat gggctaaatg ttttactgca tttaagataa
    24781 ctgccgctga cgcatccatc aatgaacttg tacgcccggt aatgatgact tcatctggta
    24841 attcgattgc aatcacagca gaaggatctt ttgtaggact ttgcgcttga atcttatctg
    24901 catagtcatg ggcagggact accacgtttc ggtcttcagg acgtaaaccg acttcttcca
    24961 taatcagttt gattcgatta actgcttctt cgtcgatcaa tccttttttg aagtcgcatt
    25021 ctgtttggaa ataacgacgg atgatttctt gtttagaggc ttcttggaca acggtatcat
    25081 ccacgatccc aaatcctaca cgattcacac ccatgtcagt aggagattga taaacagatt
    25141 ctttaccagt aattttttca ataatacgtt tgattacagg aaatgtctca acatcccgat
    25201 tatagttcac agctacttta ttgtaggcat caaagtggaa ggaatcgatc atattgacat
    25261 cttttagatc gactgtggct gcttcataag caatgttcag cggatgtttc aacggaacat
    25321 tccatactgg gaaagtttcg aacttggagt aaccagctgc atgtcctttt tggctttcat
    25381 gatacagttg gttcaagcaa gtagcgagct ttccacttcc tgggccagga gctgtcacta
    25441 caacgattgg tttagttgtt tcaatatact cattttttcc aaaaccatct tctgagacga
    25501 ttttttctac gttgactgga tagtcttcga tttctgagtg tttatagacc ttgatgtttc
    25561 gtctttctag tttattgata aagactttcg tggcaggctg tccactatag cgagtgataa
    25621 cgacactgtt gattaataag ccataaccac gtaattcatc gattaaccgc aagatatcca
    25681 tatcataagt aatcccataa tcaccacgga tcttattacg ttcaatatct ccagcataga
    25741 cgcaaatcag tatttcagct tgatctttca atttttgcag caatttgatt ttcgcatctt
    25801 cttcaaatcc tggaagtaca cgtttcgcat gcttgtcgtc aactaacttc ccaccaaatt
    25861 ctaaatataa tttgtcatag tggttcactc gttccaaaat atacgctgac tgctcttcaa
    25921 tatatttttc tgaatcaaaa ccaatttttt tcactaggtt ccctccttaa gtactaaagc
    25981 attttttcat ttttttgagg attcgtcaac tggaagagcg aaattcctca aaaaaacaaa
    26041 gaaaatggtt taaaccaact tgtctagata gttattcatt ggtatgatag tttttgataa
    26101 ggaaggtgct acatgaaaaa aagacagaaa aagaaaaacg catataaaca ctatatccgt
    26161 tcgattttta ccggttatga aagaatgctt gaagatcccg aattggaaca attgacgttt
    26221 acttatctaa acgaagaaac gcagctaact cgtgatgagc atcagcgcat tcatttcaca
    26281 acaagagatc tgcctagtaa ataaaaaata agataaaggt catcggattc gattctgtcc
    26341 tatcagatgg aaagactagt tgatcgaaaa aaaggctgta ccaaattttg gtgcagcctg
    26401 ttttatggag cattgcccgc tcttttttat aacaattttt tacagaaaat ggtactattg
    26461 aagtattaat aagtgaaaaa cagatgagta agaggaggca agtagtatga aagagccaga
    26521 tacaaatgca aattatgagc cagacgaact agaggagacg aacgcggatc aggatacagg
    26581 acaagaatcg tcttcttttt acgatatcaa agaaaaagca agcatgaatc tttcccaatt
    26641 attagaagac ttacaggctt ttgaaaaagc tgtccgcgaa gaagatatcc ctgagatcta
    26701 ccgtttatac aatggccgat tgaatgaaga attaaaaaga agctcaaatg aaaatcacga
    26761 gatcgatcaa ttgctgatgc gtaagatcca tgatcgtttt ttacaggaat ttccttttat
    26821 ggaacaagta gaaaacatct cgccaacgat gagctattac aaaatcggca cttattacca
    26881 tgatcggccc acggtcggta ttgatgcaag tctgccagaa atttttgttt tgcctaagat
    26941 cgatgaagag tgggagaaat attcccaacc ggagtcaacg gactatgaca aaaaaatcaa
    27001 tgagctagac gcaaaggtga tcactgctca gacagaaatt gaacgtttag atgaacaaat
    27061 aaaagaaatc aatcgacaaa tgactgattt gaacgacaat aaaggattct tgaatcgtaa
    27121 aaaaatcgag gaagaaattc aagaattaga gaagaagaag caagtactat ctaatgaaaa
    27181 attaggctgg cttccttata ttgagacgcc tgaaacaatc cagcagcaaa aagaagcatt
    27241 gaagcaagaa gcaagagcag accagcttcg tgcagccatc gtagaaaaag aacaaaggca
    27301 aatcagacgc tatttcggta gcaaagaggg attcggtcaa gcaatccatg aattcttgat
    27361 gaattatctt ggcaatgaga atcctaataa tcaatctaat gaaggaggtt ccgagtatga
    27421 atgaacacga tgaagcagaa tggacaaaaa atgaagaaca aacagaagat catgaagaaa
    27481 cgaacacttc attggaagaa caaacaagta atcctctgga tgacacagaa gaaatcccta
    27541 tgctagagga aacaaaaata catgaaaaag aaaaagtaac tccgacgaat acgaatactg
    27601 cagaaaacac ccatgcttac gaaataactg aaaatcccgg gtatttagaa ggaaaagagc
    27661 aagatcatca agatatcgtc agtttgattg aaacagcgga agcagaatta gcggatttac
    27721 gtatgagaaa agatttgatc gaatcagatt ttccacaatt attagaatca tatgatcgtt
    27781 ttatattgaa tgaagaacca atctccacga tcggaaagac aagcctgatc gaatacttca
    27841 cgtatgaatt actgaaaccg ttgaatgata ttggtctgga acggtcaaat tcagcttatg
    27901 acacatggaa aacaagacat ttttcgatca attatacgtt gaatggacaa aacgaattag
    27961 tcttttcctt tgtattaccg accatcgatc aacgatacca agtggaatcg atgagtctcc
    28021 taaacgtatc accagagaca atggaaatca atgtccaaga tgaccgggtg ctttctttga
    28081 tccgacactg gtcagtggat cgagtattct ctgcagggca gatcacgata ttcaatcaca
    28141 aattgaatca attattagcc catgcaagaa cacttggttt taccgttaat cagacattac
    28201 tagacaatac gaagccactt cgtttgaatc ttcagagcga atttgaattg acgaatgaag
    28261 tattggatga tatttttatc gtggcaatga aaaatccatc ctacgatatg gaaaagatca
    28321 acgaaactac ttatcaagta cgattagata aaggacagtc tttaacgata acaacaaacg
    28381 aaaaagatca aacagtcttg tcgatctcat ctggagacta cccacgatct gtcattgatt
    28441 tctttatcaa ttacgaattc ttggtcccat taatggtgag aaagtcctga ttggataagt
    28501 tggattacca gatgtcattc agataattct gttccaaagg acttgcggca gttatccaga
    28561 ataattgtca caagtctttt ctgtatgtac taaatggacg tgaataactt gctgatgaag
    28621 gagggatttc attaggaatg tccacaaata aaatagcaca gcttagctta ttgtctgctg
    28681 cttgtgtagc aggtaggatc gcttttcaat ttattccgaa tttccagcca atgactgcta
    28741 tttttttatt tatagtactt tacttaagct taaaagatgc gttaattgtc atgagtcttt
    28801 ctattgcgat cagcagtttt tattttggtg ttggaccatg ggtcatcggc caatggatca
    28861 gctatactgt tgttctgagt ttgttttcaa tcgtctgctt gagaaaaaca gtgcaaagga
    28921 atctatggtt aaagggagtc tgtttttttc tggcgggcat ggtttacgga ataggtatga
    28981 ccgtttttga tacgctgtta tatcgtttgc ctcaaccttg gatctattac cttcaagggg
    29041 tgtcgtttga tttgatgcac agtataggca atgttgtgtt ctttcttgtt tttctgccag
    29101 tcgtcaaacg tttttacaat cattcaggag gaaaaaatga aaaaaataat ttatagtttg
    29161 cttgcaatga gtgtcagtat actcattttg acaagttgca gtacaaccta tacacaatcg
    29221 gcttccaacc aaaaggagga agtaaaaaca tcgcaaaaag caacaatcac gttacaagaa
    29281 aatggtcaaa acttttcgga aaaagaagtg gtcttcaaaa aaggcgatga tttactgagt
    29341 attttgaaac gaaattttga agtcaaagaa gataacggct tcatcacttc gcttgaaggg
    29401 cactcacagg atgagaaaaa tcaactctat tggatgttta ctgtggacgg gaaaagtgct
    29461 actactggtg ccaaagagat caaattgaat gatggacaat cggtcatttt caatttgtct
    29521 aaactataag tttcataaaa aactgttaaa gggcgaatat tgccataatt cagtgagttc
    29581 agttgatgaa agaaggaaaa taacatggaa aattttaaaa aaagcggaat gttttccgta
    29641 attgctgctc taggggctaa tattctagtt gctatcagca aatttgtcgg ctatgcaatc
    29701 agtggcagtg ccgccatgct aaacgaaagc atccacagta tcgttgattg cagcaatcag
    29761 attttgctgt tattcggtga taaacaagcc aataaaggac agagcgagtt gcatcaattt
    29821 ggtgaaggac gagcaaaata ctttttcagt acaatcgtcg caatgatgct tttcttcggc
    29881 ggtggggcac ttggggtgat ggaagctttt gaaaagttga cgcatccatc ccatgaagtg
    29941 ggtaatccga tcattgttat agcaatactg ttatttggtt tggtaatcga aggaagttcg
    30001 ttacgcgtgg caatgaaaga aatcaaagaa ttgaatactg aaaaactttc cacgatgcgc
    30061 tttttgcgcg aaagtcgaca cagtgaaata ctgattattt ttacggaaga cttgtgtgct
    30121 gtaatcggtt tggtcttggc tttagcagga acaatattga cttatgcaac cgggattgct
    30181 gcatttgatg cgatcagcgg attgctgatc ggtttcttgc tgatgggagc cgccattttc
    30241 ctagcaaaag aattttatag tctgatcatc ggtgaaagcg tgacagcaag cgatttatca
    30301 aaaatcaagt tagcttttga acgtcctgag atcagtcggc tgatcgatat aaaaacagtt
    30361 catttaagtc caacggagat tttagttgca gcaaaagcag atatcgttgg taacaaagag
    30421 aatgaagctt actcggtcat caatgatatt gaaaaaaata tgcgtcagtc tcttcctgac
    30481 aagaagatgt atatatacat tgaaacagat aaatatgacc caaattattc tcgtaaataa
    30541 aacgtttatt catgaattga agcaaaaatg agaaaaatat aatcttgttt ttaaataaaa
    30601 cggctacaat ttagcgaatt tatgttacaa tgagtccgct gtttatttgt tgtaattaaa
    30661 ggagatattt taatgaacaa aaagaaaagt gcgccatggc ttcaagcttt gcatgcagtg
    30721 atgccacttt gtataagcta tataccagta ggattagctt gcggagtatt gttgcaaaaa
    30781 gttggatttg atcctctctt atcaggactg ttatcgattc tggtcttttc cggtggcgcg
    30841 cagtttttag ttgcatctat gcttacgacg caagcatcat ttgcaacgac attattgatg
    30901 gttttctttt tagaattacg ctatacatta ttaggagcaa gtcttgccgg ttttatgaaa
    30961 aaagaaaagc ggacgttttt ggctgtcttt tctcaatcac tgaatgatga aaactatgcg
    31021 gtgaactact taaagttttc aactgaccct tcctggaata aaagaaaggc tttatatgtc
    31081 aattggttct caatgactgc atgggccggt agcaatatga tcggtaattt tttcggctcg
    31141 gtgattcgag tagatgctga ccttgtccat tttgctttga cggccatgtt cattttcatg
    31201 tttatcatgc agatgaaaag cgcactactg atctttacag gtttattctc aggcgtatta
    31261 ggggtcgtat tcatggtatt attccaaaat actttcggat tgattgcagc aacagtcatt
    31321 gcttcatttg ccggatttat gctggagaag gcattcaaaa aagaaaaagc taagaaacta
    31381 agagaccgcg gtaaagatgt caatgagccg ctcttcaact tcccggaaca ggaggccaat
    31441 caccatgact aaactatatt tgctactttt agttgcttgt ctgttcatcg tggcatatat
    31501 cccgcgcttg ttcccgatgc tttattttac tcatcgaaaa gtgccatcct ggttcagtga
    31561 ctggatgaaa tatgtaccgg tggcattatt tgcggcgtta gcttttaaag atgttttcat
    31621 tactcatgaa catctggata ttgcttggaa tatcaaaata gctgcaatga ttctagtagc
    31681 aggcgtggct tacaaaacac gttcgatggc gttgtcagtt ttgacaggac ttgcgtctgt
    31741 ctttttgctg tctatgcttt aaactgtttt attttattaa aaacagagat tgcgacataa
    31801 gttgttcaaa ctgatctatc cgaactgcat ttgcaacagt caattctgga tgcaagttta
    31861 ttcgtaggga taaaaaagat tagtgttggc ttatgatgca agctcttttt tattttagga
    31921 attagagagg gatttgtcct tctatgattt tttgctataa tagggaagat gtttatttta
    31981 tgaaagaata gttgagggaa tttaaatgaa taaaaaattg atgcaaggaa cattttggct
    32041 aacctttgct aatcttctat gtaaagtttt aggggtagtc tatttgattc cctggctaag
    32101 tatgatgggg aacaatcaag atggtatgct tgctacgaca ttgtataatg ttggctatct
    32161 tccttatgga ttgttcctga tgcttggtac agtcggattt ccaaatgcga ttgcaaaaaa
    32221 agtagctgta gccacaaaag aaggagataa cgctgcttgt cggctgattt ttagaagtac
    32281 gatcaatatc atgtttgtca tcggtatcgc ctctgctgca ctgatgtatt tatttgctcc
    32341 tttactagcc ggaatcagtc cgattgctaa cgttaataat gggatactag ctatcagaag
    32401 tttatgccca tctttgattg ctatcccaat tcttagtgca atgagaggat atttccaagg
    32461 aaaaaatgat ctgcggcctt atggaacttc tttgattatc gaacaggctg tgcgagtgat
    32521 cgttatcttg gctggtactt attacttgcg cgtattgact gacggaacca tattagaagc
    32581 tgtattgatc agtacagtcg cttctttctt cggtgggtta gctgcgatta tccatatgta
    32641 tatcgtcgga cgcagaaaag acttcttcga acttaaagat tttttgattt ccagccgtta
    32701 tttcgaaaga gaaaaccgat ctgcctctgt ctctatcatt cgggaaacac taccgtttat
    32761 ttttgtcggc tcagtcatta ctatcgttca aatgatcgac caagtaacga tgaaaccact
    32821 gcttcacttt ttccgtccag agatcgcaga tcagcaactg gaattcttat tcagccgtgc
    32881 ttctgtcaat ccaaataaat tgacattgat cctgatctcc atggtaggaa cagtagctat
    32941 aagcagcttg ccaatattaa gcacgatgaa gaaaaaagat cggatacaaa tcgaaaaaac
    33001 agtaggagat agtttttcga ttgcgttatt gattcttctt ccttcattga ctggaatgtc
    33061 tttattagct ggaccactat acacattgtt ttttggctat gatcctgaaa gtgtcggata
    33121 tttccaaatg gctttgctag cttctttgtt tttctcttta ttcacgatcc tatctacgat
    33181 gcttcaatct ttgaatcacc atcgttttgc gatccgatta actgtagaag caattatcct
    33241 gaaagtcatc ttccaagtaa tcggattagg attagttggc ggatacggga tgagcttatc
    33301 aaatggctta gcattcggta ttgtctttgt tcgcggctat cactttatgt gcaaagaata
    33361 ccgaatagca cctttagcaa agatcagcaa ttttttctta aaaactttcc gctccaccct
    33421 gattatgctt gcagtatgtt ttgccgtttt ctttttgctg aatcagcgat tgtcaatgga
    33481 atcaaaaagc tatgcaatga tttattgtgt ggctgtagga agtattggcg gcttagtatt
    33541 tttattttct caattcggaa aaaatgggtt tcgaatgttg aaaaatgtta aacatcatag
    33601 cagaagcaaa gaataggtta actaatcgtt ttttgctgtc acttgaaaaa cggcaactcg
    33661 tatgattacg cttgtcgttt ttctattttc caattttagt ttcatatcta atcttactta
    33721 tgatatagtt ataaggtctg gaaaaattct ttgaaacgag gaaattaaac acatgaaact
    33781 tgcagtagtt acagatagtt cggcatatct gccggaacgt atcaagaacc atcccgactt
    33841 attcgttatt ccaatccctt tgattatgga tgggaaaatt tataacgaag gaatcgatat
    33901 cgaagcggat gaatattatg gacttttaaa aaacagtaaa gattttccta ctacttcaca
    33961 acctgtcgta ggggaagttt tgggtttata tgaggaattg aaagagaaag ggtatgacac
    34021 gattttaagt atccatcttt cttcagggat ttctggcttt gtcaacacat tatttgcgat
    34081 gaaagatgac atcagcggag taacggtcat tccttatgac tctaagatca ctagtatgcc
    34141 gatgggacac atggtagaag ctgccttaga cttaaatgat gaaggtcagt cccttgatga
    34201 aatacttgca catatcgatc gaatccgaga taatacctat gcttatctga ttgtagatga
    34261 tttgaacaat ttagtacgag gaggacgttt gacaaatggt gcagcgctga ttggcagctt
    34321 attaaaaatc aaaccgatcc tgacattttc tgaagggaaa attgttttat tcgaaaaaat
    34381 ccgttcaagt aaaaaagcat ttgctcgagc tgaagaaatt attggtagaa gaaataacga
    34441 aatacaaccg ccagtcaaac tttacgtgat acatgcaaat aatttagaag tagcgattgc
    34501 ggagaaagag aaattgcaga aaaaatatcc aaatgcagaa atcgaaattg gtcatttcgg
    34561 accagtcatt ggtacacatt taggtgaaaa agccatcggc attgccattt cagcgcaata
    34621 attcctttta ttcaaaaaac ataccaaaaa tat
//
LOCUS       DBGZHO010000024        33592 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.024, whole genome shotgun sequence.
ACCESSION   DBGZHO010000024 DBGZHO010000000
VERSION     DBGZHO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.024"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            74..1735
                     /locus_tag="ACN3HL_001357"
     CDS             74..1735
                     /locus_tag="ACN3HL_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8006245.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1805..2152)
                     /locus_tag="ACN3HL_001358"
     CDS             complement(1805..2152)
                     /locus_tag="ACN3HL_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HHC8006246.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2236..3177
                     /gene="opp3b"
                     /locus_tag="ACN3HL_001359"
     CDS             2236..3177
                     /gene="opp3b"
                     /locus_tag="ACN3HL_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HHC8006247.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3178..4221
                     /locus_tag="ACN3HL_001360"
     CDS             3178..4221
                     /locus_tag="ACN3HL_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006248.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4227..5297
                     /locus_tag="ACN3HL_001361"
     CDS             4227..5297
                     /locus_tag="ACN3HL_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006249.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5287..6240
                     /locus_tag="ACN3HL_001362"
     CDS             5287..6240
                     /locus_tag="ACN3HL_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006250.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6252..7262
                     /locus_tag="ACN3HL_001363"
     CDS             6252..7262
                     /locus_tag="ACN3HL_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HHC8006251.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7547..8368)
                     /locus_tag="ACN3HL_001364"
     CDS             complement(7547..8368)
                     /locus_tag="ACN3HL_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HHC8006252.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8465..8743)
                     /locus_tag="ACN3HL_001365"
     CDS             complement(8465..8743)
                     /locus_tag="ACN3HL_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006253.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9011..11020
                     /gene="metG"
                     /locus_tag="ACN3HL_001366"
     CDS             9011..11020
                     /gene="metG"
                     /locus_tag="ACN3HL_001366"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HHC8006254.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11499..12086)
                     /locus_tag="ACN3HL_001367"
     CDS             complement(11499..12086)
                     /locus_tag="ACN3HL_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006255.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12261..13583
                     /locus_tag="ACN3HL_001368"
     CDS             12261..13583
                     /locus_tag="ACN3HL_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHC8006256.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13738..14514
                     /locus_tag="ACN3HL_001369"
     CDS             13738..14514
                     /locus_tag="ACN3HL_001369"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HHC8006257.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14507..15076
                     /gene="rnmV"
                     /locus_tag="ACN3HL_001370"
     CDS             14507..15076
                     /gene="rnmV"
                     /locus_tag="ACN3HL_001370"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HHC8006258.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15069..15953
                     /gene="rsmA"
                     /locus_tag="ACN3HL_001371"
     CDS             15069..15953
                     /gene="rsmA"
                     /locus_tag="ACN3HL_001371"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HHC8006259.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16404..17033
                     /locus_tag="ACN3HL_001372"
     CDS             16404..17033
                     /locus_tag="ACN3HL_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006260.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17157..18266)
                     /locus_tag="ACN3HL_001373"
     CDS             complement(17157..18266)
                     /locus_tag="ACN3HL_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006261.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18475..18897
                     /gene="mgsA"
                     /locus_tag="ACN3HL_001374"
     CDS             18475..18897
                     /gene="mgsA"
                     /locus_tag="ACN3HL_001374"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HHC8006262.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19084..19182
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19220..19756
                     /locus_tag="ACN3HL_001375"
     CDS             19220..19756
                     /locus_tag="ACN3HL_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HHC8006263.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19796..21559)
                     /locus_tag="ACN3HL_001376"
     CDS             complement(19796..21559)
                     /locus_tag="ACN3HL_001376"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006264.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21562..23277)
                     /locus_tag="ACN3HL_001377"
     CDS             complement(21562..23277)
                     /locus_tag="ACN3HL_001377"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006265.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24056..24280)
                     /locus_tag="ACN3HL_001378"
     CDS             complement(24056..24280)
                     /locus_tag="ACN3HL_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006266.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24471..27248
                     /locus_tag="ACN3HL_001379"
     CDS             24471..27248
                     /locus_tag="ACN3HL_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8006267.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27329..27748
                     /locus_tag="ACN3HL_001380"
     CDS             27329..27748
                     /locus_tag="ACN3HL_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8006268.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27760..28230
                     /locus_tag="ACN3HL_001381"
     CDS             27760..28230
                     /locus_tag="ACN3HL_001381"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8006269.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28247..29026
                     /locus_tag="ACN3HL_001382"
     CDS             28247..29026
                     /locus_tag="ACN3HL_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHC8006270.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29013..29834
                     /locus_tag="ACN3HL_001383"
     CDS             29013..29834
                     /locus_tag="ACN3HL_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8006271.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            29851..30900
                     /locus_tag="ACN3HL_001384"
     CDS             29851..30900
                     /locus_tag="ACN3HL_001384"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8006272.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            30913..31917
                     /locus_tag="ACN3HL_001385"
     CDS             30913..31917
                     /locus_tag="ACN3HL_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8006273.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32550..33569
                     /locus_tag="ACN3HL_001386"
     CDS             32550..33569
                     /locus_tag="ACN3HL_001386"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HHC8006274.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        10960 a         5963 c         6876 g         9793 t
ORIGIN      
        1 ttattcatta aactcttaaa caacttcaga aaatattaat tattctgaaa attccaataa
       61 aggggtacgt aaaatgaaaa agaaatttac atttggtttg gttgcggtat gcggccttgt
      121 acttgctgga tgttatggcg gcagttcagc cacaagcagt agttcagcaa aaagcggttc
      181 agcagatgga ggaggcgtat ttaacttagt cgtgcctcaa gaaatgccta cagctgactt
      241 atcagttgca acagatacaa tcagttttac agcattgaat aacgtttatg aaggaattta
      301 ccgtcttgat gaagacagca aaccacagcc ggcaggagct agcgagttgg cagaagtcag
      361 tgaagacgga ttaacttaca aaatcaaatt acgagaagac gcaaaatggt caaatggtga
      421 tcctgttaca gcagcggatt acgtttatgg ctggcaacga acagtagacc cagctacagc
      481 ttctgaatat gcttacctgt atgcgccagt tgaaaatgca gaagacatta cagctggaaa
      541 gaaagataaa tcagaactag ggatcaaagc agttggtgac tatgaattag aaatcaaatt
      601 gacgaaacaa acaccatatt tccaatatct gcttgctttc ccatcatttt tcccacaaaa
      661 acaatccgta gtggaagaaa atggggatgc ctatgcatct gcaagtgata aagctgttta
      721 taatggacca ttcacattag aagattttga tggaccagga acagatacag aatggactta
      781 taagaaaaat gatcattact gggacaaaga tacagtaaaa ctttctgaaa tcaaagtcag
      841 tgtagtaaaa gaatcttcta ctgcattgaa cttattcaaa gatggccaag cagatgacgt
      901 gatcttgtct ggtgagttag cacagcaaaa cgcaaacgat ccagcttata cttctgttaa
      961 agaagcgcgg acaagctata tcgaattcaa tcaacgtgaa aagaattcac cattcaacaa
     1021 tgtgaaccta agaaaagcta tttcttattc tatcgatcgt gaagctttag taaaacaagt
     1081 actaggtgac ggatcagttg tctctacagg attgatccca tcagatatgg taaaaagtcc
     1141 aacaacgaac gaagactttg caaaagaagc tggaaaatta gtttcttatg acaaagataa
     1201 agcaaaagaa tattgggaaa aagcgaaaaa agaattgggc gttgattctt tagaatttga
     1261 tttgatggct tctgatgatg attcatcgaa aaaagtaatc gaatatgttc aaaactcaat
     1321 ccaagaaaac ttggatggcg taacagtcaa accaacacct gttccattct ctgtacgtct
     1381 tgaccgctca acttcgggtg attttgacgc agtactaggc ggatgggctg ctgactatgc
     1441 agacccaagc agctttactg atttgtttgt cacaggtaat tcatacaacc gtggtcgctg
     1501 gagcaatgca gaatatgacg aagcagttaa agcagcttca tcaacagacg ctggcgatga
     1561 acaagcccgt tgggatgatt tccaaaaagc aatcaagatc atctctgatg atatgggtgt
     1621 cgttccggtg taccaaaaag cagaaggtca cctagtgaat gaaaaaatca aaggtatcgt
     1681 tcaccatgcg gcaggcgctt catgggatta caaatggaca tacgttgaag aataatcgtt
     1741 aataccgtga gcatgagaaa aaacgaggct gcggcaaatg tcgcaacctc gttctcatat
     1801 tcacttatcc taacaaagaa aaaagcatga aaatagcaga aagagcaatt agtattccgg
     1861 caatgatcag ccaaaagctg tacataccgt agctggcaga cgagagcgag gaaaattctg
     1921 gttttttctt tcggttcctt gttcgtgcaa gatggaccga tcgctgaaaa tgatcgaaga
     1981 aacccgaaga aaagacccat aaaaaaccgc cgataatcag aaacggcaat gaccataaga
     2041 atagatcatt agataattga atgagtgtaa aggaatggtt gatgagattt tttattaaaa
     2101 taaccagaat cagtagaaaa gctactgcgt aggggataga tttttttttc atttgattgc
     2161 tcctttattt ttggttcatt atctaataat gtagcgaaac atctgtcaga agtcaaaagc
     2221 tagggggaaa cattagtgaa tagttatatc aaatatgtat taaaacgtgt ctttttcatg
     2281 atcatcacgc tttggttaat tgcaacaatc acctttttct tgatgcaatt gctgccgggc
     2341 acgccatata cgaatcagga acgtttgagt cctgaaacaa tcgagatgct aaataaacaa
     2401 gtcggtttgg ataaaccagt tatcgtacaa tatgggattt atctttctaa tttgcttcaa
     2461 ggagattttg gaatttcctt ccaatttaaa aaccagccag tcgcacattt gttagctgga
     2521 agaatcggac catccttgca gttagggtta caggcaatta tctttggaac agtcctaggg
     2581 acgattttag gaacgatctc tgccatgaag caaaatacat gggcagatac atcttctaca
     2641 ctcgtagcga tattaggtcg ttccattcca aactttgtat ttgctgtttt attacaatat
     2701 atctttgcaa tcaaattaca agttttgcca atcgcaaaat gggatggctt tgtgtacaca
     2761 atcttaccaa caattgcgtt ggccatgtcg ccgcttgctg actctgctcg gtttatccgt
     2821 acggaaatgg tggaagtact gcatagtgat tatgtggaat tagcaaaagc aaaaggattg
     2881 agccgttggg aaatcgcctt taaacatggt cttcgaaata gtttgattcc attgatgact
     2941 ttattaggac cgttagctgt agcattgatg accggatcac tggtggtaga aaatatcttt
     3001 gctattcctg gtatcgggga acaattcgtt aagtcaatca caacaaatga ttatcctacg
     3061 atcatggctg taacgatcct ttactcattt atgctgattt ttgttatttt gatcgtggat
     3121 ctattgtacg gtctagttga tccaagaatt cgtgtttcag aagggagccg aggataaatg
     3181 gaaatgatac caaagcgtta tgaaacagtt gcagatatcc ctgcggatga atttcttcca
     3241 ttacaaaaaa ataccgaaga agaacgtgaa cagattactg caccttcttt gaattttatc
     3301 caagattcat ggcgccgttt aaagaaaaac aaagctgccg ttatttcaat ggttttacta
     3361 ttggtcatca ttttgatctc tgtgatcaca atctttgttt ctcctcatga tccaactgcc
     3421 caaaacgtgg cttatatcaa tttgcctcct cgtattccgg gaatcaatat cgatggattg
     3481 aatggaaaag caatggttgg tggtgaactt gttgataaat atgctcaagc aaacgtccct
     3541 tcaaacgtaa atttcttttt aggaacagac ggtttgggac gtgatgtatt aagccgctta
     3601 tttatgggaa tgagaatctc gttgctgatc gcatttattg ctgcattact agatgtaacg
     3661 attggtgtag cttacgggtt ggtttctggt ttgttaggcg gacgtgtcga taacgtgatg
     3721 caacgttttt tggaaatctt atcaggaatt ccaaacctcg ttgtcatgat tttgatgttg
     3781 gtcgtttttg aaccaggaat tttttcaatc gtggctgcta tggccatcac aaactggata
     3841 ccaatggcac gtatcgttcg tgcacaaaca atgaaattaa aagatcaaga atatgtttta
     3901 gctggattga cattaggtga atcaagaatg aaaattgcat tcaaacatat tttgccgaat
     3961 atctctagtg tcattattat tcaaatgatg tttagtattc catctgctat tttcttcgaa
     4021 gcctttttaa gctttatcgg tttaggtctt acgcctccgt cagcttcatt aggaacgatg
     4081 ttgagcgaag ggtacaagac attcctgtat ctgccttatc tattatggat tccggcagta
     4141 actttatcgg ttatcatgat tggctttaac ttacttgctg atggattgcg tgatgccttt
     4201 gatcctaaaa tgaaagagtg aagacgatga cgaaaatttt agaagtgaaa gacttagaaa
     4261 tctcttttga tacgtatgct ggaaaggtac gagcgattcg cggtgtcaat tttcatttga
     4321 ataaaggaga aacattggcg atcgttgggg aatctggaag tggaaaatca gtgacgacca
     4381 gaagcatcat gcgcttgctg tcaagcaacg ccaatataga tgctggtcaa atcctcttta
     4441 aaggtaacga tatcgttgga aaatcagaaa gagagatgca aaaaatccgt ggtaaagaaa
     4501 tagcgatgat tttccaagat ccaatgacct ctttagatcc gacgatgccc attgggaagc
     4561 aagtcgctga gtcccttaga aagcataata aagtttcaaa aaaagaggga caaaaagctg
     4621 cattagaatt gcttaaatta gttggaatac ccgaagctga gaaacgtatc aacagttatc
     4681 cgcatcagtt ctcaggaggt cagcgtcaac ggatcgtgat cgcgattgca ctggtatgtt
     4741 atccggaaat cctgattgct gatgaaccta caacagcgct tgatgtgact attcaagcac
     4801 agattttgga gctgctgaaa gaaattcaga caaaaatcga tacatcaatt atctttatca
     4861 ctcatgacct tggtgtagta gcgaatgtcg ctgatcgtgt cgctgtcatg tatggaggaa
     4921 gaatcgttga agttggaaca tcggaagaaa ttttctacaa cccgcaacat ccctatactt
     4981 ggggactgct tggttcaatg ccgacattag atagtgcgaa cgatcgattg tatgctattc
     5041 ctggttctcc accggattta ttgaacccgc caaaaggaga cgcattctat ccaagaaatg
     5101 aattcgcgat gaaaatcgat gcagaacaag aaccaccatt ttttgaacta tcaaaaacac
     5161 acaaggcagc aacttggcta cttgctccgc aggcacccaa agtgacaccg ccagaagaaa
     5221 tccaacgtcg ctgggctatc tttaaagaga aacaaaaaca tacttacggt caaggaggaa
     5281 ttgctgatgc caaataaact acttgaagtt aaaggattga aacagtattt caatgtagga
     5341 aaaaagaatg aagtacatgc tgtaaatgac atcagctttc acatttatga aggagaaaca
     5401 ttcggtttag ttggagaatc tggaagcgga aaatccacta ctggccgtac gatcattcgc
     5461 ttgaatgaac ctactgatgg tgagatatta ttcgacggtc aagatataac gaagatcaaa
     5521 gataaaaaag gtttgacgaa attccggcat gatgttcaga tgatctttca agatccatac
     5581 gcttcgttga atcctcgtat gaaagtcaga gatatcattg ccgaaggaat tgatgttaat
     5641 ggactagcta aatcatctga agagcgtgca aaaaaagtcg atgatctatt gagaactgtt
     5701 ggattgaatc caagccacgg tactcgttat cctcatgaat tttcaggtgg gcaacgccag
     5761 cgtattggta ttgcacgagc attggcagta aaaccgcgtt ttatcatttg tgatgaacca
     5821 atttctgcac tagatgtgtc gatccaagcc caagtggtca atttgttgca agatctccaa
     5881 aaagaacatc aattgaccta tctatttatt gcacatgatt tgtcgatggt taaacatatt
     5941 agtgaccgaa tcggtgtaat gcataacggc ttgttattag agatgggaac aagtgatgaa
     6001 atctataatc acggtgttca tccttataca gaaagtttgt tatctgctat tcctctacca
     6061 gatccagacc atgagagaaa acgcagaaga atcaaatatc aacctgaacc agatgacgga
     6121 caagtacgtc aacttcgtga aatcgcacca gaacattttg tctatgcaac tgagcaggaa
     6181 gtcccatatt acgcaaaaaa actaaaacga caaaaggaat ctcttctggt tgctaactag
     6241 gagggacata gatgctaaaa gcttttaaat tccgtatgta tccgacagaa gaacaaaaac
     6301 agcaattgat tcgtactttt ggatgtgctc gatttaccta taaccatttg ctgaaaaagc
     6361 ggcagaaaag ttggcaacaa acaggagtag ccaatttttc gctcacaccc gctacattaa
     6421 aaaaagaata cccattctta aaagaagtag acagtcttgc tttagcaaat gcacagctta
     6481 atttggatcg ggcttttcgc aattatttca agggacgtgc cagcttccca aagcttaaaa
     6541 cgaaaaaaag tatgtggcaa tcttatacga ccaacaacca aacccgtacg atctatctgg
     6601 aaaatggcta cttaaagtta ccaaaacaaa aagaactaat caagataaat cagcatcggc
     6661 cagttgaagg atcgattcgc tccgctacga tttctgctcg atataatgaa gaattttatg
     6721 tcgcactact ttgtgatgtt tcgccagtaa aaaaagaatc tttagctaaa tggatcggga
     6781 tcgcctatca tccgaagaca ttgatccaaa catctcgacc tctagaagta actttaccaa
     6841 aatttcacca gacagaagaa aagctgcaac atgcacagcg gaaattgaat gtgaaagtcc
     6901 gctccgctca ccatagaaag atcaggttag atcaggcaag caattatcag aaacaaaaga
     6961 gaaaagtaat ggatctttat ctgaaacaaa agaaccagcg agaagattat cttgaacaat
     7021 tatctgggaa attggtcaaa caatatgact acttatttgt agaatctttt ccaaaagaag
     7081 aggcacatgc tgatttttct attcacgact ggcataaatt aataacaaaa ttgcgttata
     7141 agtcccaatg gtataataaa aaatttcttt tgatcaatac cgacggagca gaagaaagca
     7201 attccgtaag aaagagccaa gtagtagaaa aaatgggcag acattcggtt atcaagggat
     7261 aaaaaatgaa tgaaactgat aggagcgtta gggttagcct tgttaataaa aagtcttaat
     7321 gacttttgtt tctaggaatt tttcttttga agaaaagctc actaattatg acaaaccaat
     7381 aaaacaatag cagaaaaagt tcgtacgagc tttttctgct attgttaatt ttttattcag
     7441 aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa gagttgtttt
     7501 tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat tcatggtgcc
     7561 ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt tcaccgatct
     7621 catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt ttataatcga
     7681 tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct ttacctaaaa
     7741 cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat gctttcaaga
     7801 tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca gtgactaaat
     7861 caagcgagat agccacttct ccgctagata aatggatctt gttactatga cgttctagtg
     7921 tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct ccaataaagg
     7981 ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta ctgaatgtat
     8041 gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt gtttctctta
     8101 agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat gcccatgaat
     8161 ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct tcttctttgt
     8221 tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct ggacgttcct
     8281 gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa tataattttt
     8341 cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta aaagtacttt
     8401 ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa atctaggtta
     8461 tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa agcagataaa
     8521 acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata acgatatata
     8581 cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa tgcccatgga
     8641 ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt gctaatgaaa
     8701 gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt ccagtccctt
     8761 actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa gccgtttttt
     8821 agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc ttttaaagga
     8881 tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa aaaagctaac
     8941 agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc gataaaggag
     9001 gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct attatccaag
     9061 cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa ttgctcgtta
     9121 taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac atggtcaaaa
     9181 aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag ataaaatggc
     9241 ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat tcattcgcac
     9301 gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat tagaacaggg
     9361 agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag aattctttac
     9421 agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg gtggtaaagc
     9481 gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc gcatgagcaa
     9541 atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc agccagaatc
     9601 tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc ttgcagtttc
     9661 acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg tggtgtatgt
     9721 atggatcgat gcattatcca attatattac tgcactagga tatggctccg aagatgaaag
     9781 tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa tcgttcgctt
     9841 tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac ctaaaaaagt
     9901 atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa aaggaaatgt
     9961 cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt attatttgct
    10021 tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg tttcccgtgt
    10081 caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg ctatgatcaa
    10141 caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat ttgatagtga
    10201 actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg aaaaaatgga
    10261 attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca aatacattga
    10321 tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat tgaatagtgt
    10381 catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc caatcatgac
    10441 agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa tgaatcttga
    10501 aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag gtacaccaat
    10561 cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa tgtctgaagg
    10621 tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac ttgtttcaac
    10681 gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag tagcagaagt
    10741 catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac tagatgctgg
    10801 agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg atccaagcga
    10861 attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga tgcgtggaca
    10921 aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac aagtaatcga
    10981 agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag ggggtatgac
    11041 actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt aaattccttc
    11101 ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa taaatcctag
    11161 aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa taggaatcgt
    11221 aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga ttcatctggt
    11281 actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta ttacatctat
    11341 atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt tatgttcaat
    11401 tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc atcggctttg
    11461 acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt atggtaacct
    11521 tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa tgggatcgaa
    11581 aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt tgtcaacatc
    11641 acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg attatcccaa
    11701 tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata gatcccgact
    11761 aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa aatcgctgaa
    11821 agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat cccccacaag
    11881 atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag caatattagt
    11941 ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa ccaatgccaa
    12001 tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata atctgctaat
    12061 ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa ggtaggttta
    12121 gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc actgaaagtg
    12181 gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat accaaatttc
    12241 aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat ctgtttggcg
    12301 cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa actgctgctg
    12361 ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg ggtggtttct
    12421 taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg gaaactggtg
    12481 gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta ttaggatggg
    12541 cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc tttgcgacac
    12601 aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca gtgatcaccg
    12661 ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct gtacaatcag
    12721 tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga ttattgaccc
    12781 caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt acttttgtcg
    12841 aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg ttaggtgtcg
    12901 gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca attattcttg
    12961 gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg aaaactttgc
    13021 cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac gtcatttttg
    13081 gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac ggtgcattga
    13141 acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa gacgagctac
    13201 ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat gttcctgcgg
    13261 ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac tttttaacag
    13321 acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt gtctttattt
    13381 taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat ccaatcgttc
    13441 cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg acgcaaacga
    13501 aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat tatcaaaaaa
    13561 agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt acgaactagg
    13621 tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat tttgattttt
    13681 gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga gataaacatg
    13741 atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat tccagaaacg
    13801 attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt cgatacgcca
    13861 acgattgaaa agtctttgca attaagccat gactatccaa atatatacag tattatcggc
    13921 tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt acaagaacaa
    13981 ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca ttggatggaa
    14041 gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc aaaagaaatg
    14101 aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca aatcctaaaa
    14161 gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga ttatgaatgg
    14221 gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt cactttcaaa
    14281 aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt acttgtggaa
    14341 acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga accaggctat
    14401 actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga agaagtggct
    14461 gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg ataagatgaa
    14521 gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc gggaagtagt
    14581 tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc tgatgcaaat
    14641 tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt tttcaggaga
    14701 aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt ttttgccgcg
    14761 cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa gtgatgctgc
    14821 tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg ctgtttctga
    14881 aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag caaaagaaaa
    14941 acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac aattggaaaa
    15001 acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga aaatagtgga
    15061 ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa gagattttat
    15121 tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact gaaccaaata
    15181 ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg atcgaagttg
    15241 gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa gtcgtagcat
    15301 ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc tatgacaatg
    15361 tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt agagaaacat
    15421 ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt acgacaccga
    15481 tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc atgatgcaaa
    15541 aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt tcattatcga
    15601 ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa acagtatttg
    15661 tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat ataccggcag
    15721 tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt cagcaaagaa
    15781 gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag acaaaagcat
    15841 ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg gagactttgt
    15901 cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag taaaaaaaga
    15961 ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac agccaaacaa
    16021 aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca agcttttgaa
    16081 caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa ggaacaattt
    16141 caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg caagcttttg
    16201 accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc ctatttttgt
    16261 ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg atttagaaaa
    16321 gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat ttatgtgtca
    16381 agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta acgatttctg
    16441 ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc atgattccac
    16501 cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt tttacaccag
    16561 gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca acgccggtta
    16621 tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct tggtacttgc
    16681 aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat tggcgtttcc
    16741 aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta gtagtcagca
    16801 tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat ttttatacag
    16861 tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat aatattgctt
    16921 attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg gcagcaaaaa
    16981 aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat tagacatgat
    17041 ctctcaaaaa aaaaactctc atctagtaat ggataataaa tcctctaaga tgagagtttt
    17101 ttgtcctaaa aagagctgca ccaacatctt ctggcacagc tctaacaggg ggcaatttat
    17161 ggaagtttga tgacttgttc tgtttcttta tcaaagaagt ggcctttgct gatgttgaag
    17221 gcaaggtcga ctatttcgcc tggtttatgg aaatctcttg catctacttt tgagatgaac
    17281 tcagtagaac cagtttttgt gtaaagcatc gtttcagctc caagtaattc ggaaacgaca
    17341 acttctgatt tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc actgtggatg
    17401 tcttctggac gaataccgaa gataacttct tttccttcat aacctttttc aactaatact
    17461 ttgttttttc cttcaggaat acgaagctta agcccatgtc catctgtgat aacaccattt
    17521 ttcaatgtca cattaaagaa gttcatggca ggagatccaa taaagccggc aacgaacata
    17581 ttgacgggtg tatcataaac ttctttcggt gtaccgattt gttggataaa tccgtctttc
    17641 atgataacga ttcggtcagc catagtcatt gcttctgtct gatcgtgagt aacatagatg
    17701 gtcgttgttt caagacgctg gtgaagtttg gcaatctcag cacgcatggc tacacgtaat
    17761 ttagcatcta aatttgataa tggctcatcc attaagaaga cttttgcatc ccgaacgatt
    17821 gcccgtccca atgccacacg ttggcgttgt ccaccagata aagcagctgg ttttcgtttc
    17881 aagtattctg tcagacctaa gatctctgct gcattgtcca cacgtttttt gatgtctgct
    17941 ttatcatatt tacgtaattt caagccaaaa gccatattat caaaaacagt catatgagga
    18001 tacaatgcgt agttttggaa aaccatggca atatcacggt ctttaggtgc cacgtcattc
    18061 atgacttttc cgccgatatt tagttctcct tcagagatat cttccagtcc cgcgatcatt
    18121 cgcaaagtag ttgactttcc acaaccggaa ggaccaacaa aaacgataaa ttcacggtct
    18181 ttgattgata gattaaaatc agttacagaa taattttctg cattgtcata ttttttatat
    18241 acgtttttca gagccatttc taccataata cgttccacac tttctttttt agttttatta
    18301 actatttaaa gtataaatga aagcgttaac taacttcaat gtcatgttga acaagaattt
    18361 tttctttttt ttgtcaatgt gctagtttta agctttaata aatatccata agaaataaaa
    18421 actgatacac tggagtaaat aagtatgtta acaatatcaa aaggagtgtc tcttatgaaa
    18481 atcgctttga tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc aacagcgtat
    18541 aaaacaatat tggaaaaaca tgaacttttt gctaccggga cgactgggca gaggatcacg
    18601 gaagcaaccg gcttgccgat ccatcggttt aaatccggac cgttaggcgg ggatcagcaa
    18661 attggagcca tgatttcgga ggatcagtta gatttggtga tttttcttcg agacccgctg
    18721 gctgcacagc cccatgaacc agatgtaaca gcacttatcc gtttatctga tgtctatgag
    18781 attccgttag ctacgaatat cggaacagct gaggtgctac taagaggact ggaagccggc
    18841 ttcctagatt ttcgaagaat cgtccatgaa atagacaagc atccactttc attttgatgg
    18901 ataagcgtat ggaaaaataa cgtttaatgt tcgcctatat gtagctataa aagctaaaca
    18961 aactgataat atgcgatata atacgaacgt attggataat ataaacaata atattagttt
    19021 ttcgtatttg cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag atcccaaaaa
    19081 taatacagag tagaaaataa agcgttaagt gctaagagga tgggatgttg cctcttggac
    19141 gaaggacgta atgttcgcgg ttttattttc gcattcgctg catgatacga tgtagcagct
    19201 cttaaaggag atgctaaaaa tgaagaaaca ccggttagac gcacgtatga ttgctattat
    19261 gggcttattg attgcattga tggtcacttt gtcccgactg gtagcaatcg agaccccatt
    19321 tattaaaatc agtgtcacat ttattccaca agtgatcatg ggcattcttt ttggtccttt
    19381 ttggtcaggg ataggcgcag ttttagctga tttagtagga atggccctct tctcgaaatc
    19441 tgcattcttt attggattta cattgaatgc atttattgaa ggagcaatct acggattctt
    19501 tttctatcga aaagagatca cttggaaaaa tgccattctg gctacgctta gtgtcacgct
    19561 gatcatcaac ttatttttga caccattatg gcttgcgttg atgtaccatg tgccattgtt
    19621 cagctgggtc gtttgggcgc cccgcctgtt aaaaacagta atatggttac cgattcaatc
    19681 aattgccatt tattacgtag gacgtagtat tccttacaaa aaaattttaa gaagtttagc
    19741 gatccacgct aaataaaaaa caagcagtct tcccatccca gaagactgct tgtttttatt
    19801 gtgctgtgaa ttgtgcttga tagagccgtc ggtaataacc atctttttga agcagctcat
    19861 catgggtgcc catttcgaca atagctccct gatccatcac taatatctgg tccgcatttt
    19921 tgattgtgga caggcgatgg gcaatcacaa aactggtttt tccttccatc attgctaaga
    19981 aggcttgttg gatttttttc tctgtcaatg tatcgactga gctggtagct tcatctaaga
    20041 tcaacatagg gggattactg atcatcgttc gagcaatcgt caacagttgg cgttgtccat
    20101 ctgatatctt taacccttga ccgccaatct tagtatctaa tttttccggc aaacgttcta
    20161 caaattcata catataagag gcttttaggg catcattgat ttctgcgtca cttgcttccg
    20221 gattcccaaa acgaagattt tctcgcaatg tactgtcaaa tagccaagta tcttgtaaca
    20281 ccattccaaa acttttacgt aatgtatcac gttggataga gcggatgtca tggtcatcga
    20341 ctgtaattgt tccttttgtt gtgtcataaa aacgcatcag caaattaaca agtgtggatt
    20401 ttccggcccc tgtttttcct actatagcaa tggtttgacc tggataagca gtaaaattga
    20461 aatcttcgat caaacgctgc ttggggtcat aagaaaaaga aacatgatca aaagagactt
    20521 ttcctttgat atttttgggt tccaaggcat aggcatctgg caaatcaggc ttttcttctg
    20581 gctgatcgat caaatcaaat gctcgttcta gaccagaaaa agcggtttgc agttgtgtcg
    20641 tgattccaga aagttcgata aatggtttag aaaactgact tgagtagatc gtaaagctgg
    20701 aaatcacacc aacagtgatt gacgaaccac tcttcaatgc caataggccg ccaactaaac
    20761 caatcgataa ataagcaagg tgatctacaa aacgagaaga cgggtttgtc aaggaagaag
    20821 aaaattgtgc ccgttgtcct ttttcatata gatcagcatt tagcagttca aattgctgtt
    20881 gactagcttc ttcttgctga aaagctttca cgattttctg gttaccgatt cgttcggtca
    20941 caaagcccga gatatcccca ataatccttt gctgtctatc gaaatttgtt tgtgaagcac
    21001 gagcaacgat ccaactcaca aggaaaataa ttggtgtaga acaaagaacg accaatgtca
    21061 gaagtggact tagacgcatc ataaaaataa acgaaagaat gatgattgcc actccagaaa
    21121 ataattgatt gaaggccgca gaaattgcaa tggaaatatt gtccatatca tttgtaaatc
    21181 gactgacgat atttccgtgg gagttttgat cataataacg aagtggcaat cgattcagat
    21241 gagcaaatgc atcttttctt aattttgcaa cggataagta agctaaccga ttgcttaaca
    21301 cttggatgag ccattgactg actacgttga ttaaaacgat accaccgaat agaataagta
    21361 aatggaacag tcgattgaag cggacctgtc cttctccaat catttgatcg atactttgac
    21421 caatttgtaa cgtcatcaca actgttgcaa tcccattgat gattcctagt atcacagcta
    21481 gccaaatgtc ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc gtctgcaagg
    21541 ataatttttt tactttcata actattcttc ctcctgtgat gcgacgattt cctgatattc
    21601 tgctgattga gcaagtaatt cttcatgggt accctgagca gcaatcttac cttgatccat
    21661 cactaagata tgatgtgctt cttgaataga gcggacacgt tgggagataa taatcactgt
    21721 actgccaaga taagtctgta gcgccttacg caaatccaag tctgtttgat aatccaacgc
    21781 acttaaagag tcatctaaaa tcagtaatgc tggcttggca atcaaagctc ttgcaatcgt
    21841 cagtcgctgt ttttgtccgc cagagaaatt tttcccattt tccatgactt ttgtatctaa
    21901 accatttgga agctgacgga caaattcttc tgcctgagcg attttcagag cttcccaaca
    21961 ttctttttct gtggcgtctt tcttacccca ttgaaggttt tcacgaatag tcccggtaaa
    22021 tagtacagaa gtttggggaa caagagcaat ttgctgacgg agatgatcca gctgccaaga
    22081 acgaacatcc attccgtcca ttataactgt accggaactg acatcataga aacgcggaat
    22141 caattgtgtc aaagtcgttt tcccgcttcc ggttggacca atgattccaa ggactgtatt
    22201 tcgcttcagc tgaaatgtaa tattttggag agaaagacca gaatcaggag tataacggaa
    22261 gtcaacatgg tcaaaagcga taattgcttc agaagaaaaa tcgggagtag tactgacctc
    22321 agcttcaaga atcgaatttt ctgtgtctag cacctctttc acccgatttc ctgaagcttc
    22381 ggcacgtgtg aagatcacga cgaggtttga aacaacgatc agtgccaaaa gcatttgatt
    22441 catataattg atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat ttactttgat
    22501 cccgccaact gtcagcaaac agatgatccc gacattcatg atcaaggttg tagcaggtga
    22561 taatagggca gagatattgg aaacacgtaa ataattgttc gctagatcat ttgtgctttt
    22621 atcgaacttc tctgtttctt tttttgtctg cgcaaatgcg cggatgacac gaacaccgct
    22681 aagattctga ctaacgtgtt cattgagctg atctagtttt tcttgcactt tttggtagag
    22741 aggaacggtt tttttgatga taaaaaataa aatgattgag aaaataggca ataatgctaa
    22801 gaaaaacaga cctacttccc agtcgatcac aaaagccatg accactgacc cgatacttaa
    22861 aaacggtgct ctgatcaata aacgaatgac cattgctaaa gctagctgaa gctgattgat
    22921 gtcgtttgtc attcgggtga tcaaggtatc tgttccaaaa tgattcaact cgttgtgaga
    22981 gaaagtattg atttttttga ttagctgatt acgtaactct gtaccaaatc cttgtgaagc
    23041 tactgaagca tagtattggc aaatgatagc acaaatcaga ccaatcacag acatagcgac
    23101 catccataag cccatttcaa tgatttttcc tcggtcattc atttttagtc cattatcgat
    23161 caaggaagcc atcattaaag gcaggacaag ttcgaagaca gcttcaagaa atttgaagaa
    23221 cgggcccaaa atgatttgct tacgatagtc ttttgcataa cgtaataact gaatcatatg
    23281 attcctccta ttatttattt gtctacaatt gaaaaaacaa gtactaccac attgtagctt
    23341 aggaaattta gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt attatgaaga
    23401 agctttagaa attgaataga ctattttttt taaaaaaaag aaaatgagaa aacatgccag
    23461 tctcttcatt cataggaacg tctattttac ttaatttttc tataaatgaa ttctgcataa
    23521 aaaatatatc aagtaaatgt ttatagatga aactctattt acttcttttt taatttgttc
    23581 ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa atctaattga
    23641 ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt gggtactatc
    23701 ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta tcaggtttga
    23761 tggaacgaag acaacctccc gacatcaagt caaaagctac ttgagatttt gatctgaaaa
    23821 taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt aatcaatggg
    23881 aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag tacctcttta
    23941 ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt tgttatacca
    24001 catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt gaatcttatt
    24061 ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa aatcctgttt
    24121 cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata gccatataaa
    24181 gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga aaagttttcc
    24241 aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca tagcctcctt
    24301 attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg ttttttagaa
    24361 taaaaattat aagggataag taggctgctg tctataataa gatatatttt tcaattcttt
    24421 attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg gtgaataagt
    24481 tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc gatttagaac
    24541 atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta aaaagaaaca
    24601 cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa atcaattctc
    24661 gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag ttacgcacga
    24721 atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg caaccaaaag
    24781 acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc gaacaaatca
    24841 aaacagctct ttactatcca gatggcggat taccactttt gattacaggc gaaagtggca
    24901 caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat gatctgctag
    24961 aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat cctgaacttt
    25021 tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa gaaaataaaa
    25081 aaggggcctt tgaagcagca gatggtggga tcttgttttt agacgaggta catcgcttaa
    25141 caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt tatcgtatgg
    25201 gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg actgaagaga
    25261 ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc gaactacctg
    25321 cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt tttctcgaag
    25381 aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca cttttaacaa
    25441 gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt tcagcagcaa
    25501 aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat catttgcaaa
    25561 aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc tatattacgc
    25621 aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag cgaatcgtta
    25681 aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta tattcttgcg
    25741 aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt gagaccagta
    25801 gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag acctttcgac
    25861 aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc ttgagttact
    25921 atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt atccaactaa
    25981 tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac tatgtccaac
    26041 gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg gatcggattt
    26101 tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg ccaaaagcga
    26161 tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta aatcgtttat
    26221 tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca cagcagattg
    26281 cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg atcatattag
    26341 tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta tccgtaccgc
    26401 ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa tgcctgcaaa
    26461 aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag ccagaatggc
    26521 gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc ttcactggaa
    26581 tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg gcttgtcagt
    26641 tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt gacccattat
    26701 tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc accaatatcg
    26761 actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta gctgaatggt
    26821 tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc attcgtaatt
    26881 tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag gtgatgggag
    26941 aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc agcaatccca
    27001 aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc cgacaaatgc
    27061 caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa gggttatctg
    27121 ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc cccaattctg
    27181 agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg atagaagaag
    27241 aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc ttttttagta
    27301 tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag cttcccatgg
    27361 aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa atcattctat
    27421 tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag taaggcagct
    27481 ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg gcggaagtgt
    27541 caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg ccggattgaa
    27601 tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga caactgtttt
    27661 gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg agcggctcaa
    27721 tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt gacaagagtc
    27781 gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat aggcgcagac
    27841 tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac aacgatcaaa
    27901 ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc gattgccgcg
    27961 ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc gatcgaggat
    28021 gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg agggatcaag
    28081 gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga agaggaggaa
    28141 cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt accagcagat
    28201 aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga ttgtacaagc
    28261 agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag ggacatcgtt
    28321 gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg atgtaaaaac
    28381 tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct cagtaggtgc
    28441 ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg ctattacagc
    28501 tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt tgacattgat
    28561 attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag cagacaatta
    28621 tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg gtatcggtct
    28681 ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca atacgatcgg
    28741 aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag ctacagggtt
    28801 gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac aagttgcacc
    28861 atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga ccggagtagc
    28921 tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc gtcaactacc
    28981 acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc aaaaacagca
    29041 aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg gagttttctt
    29101 ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg attttgaaaa
    29161 agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta gagtttttta
    29221 acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg gaggaagaaa
    29281 ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca tctttgatgg
    29341 gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg attgccacag
    29401 gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg ttcattttga
    29461 ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga tatcgcttag
    29521 gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg acattaggcg
    29581 cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc accatcaata
    29641 ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt tttgatgata
    29701 tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta ttgaagaaag
    29761 aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt ggttcgtgga
    29821 tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta tatctatgaa
    29881 gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag agaacatatg
    29941 aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc ttgtttagca
    30001 gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga acctttttat
    30061 tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt gtcacaaagc
    30121 gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg gttacctgtt
    30181 gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca aattattgat
    30241 ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc gactgtttta
    30301 cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag caaaaaaata
    30361 gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc gattattcaa
    30421 aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca gcgtttcgtc
    30481 accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa attgactgaa
    30541 acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg cccatacctg
    30601 gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa taaggaacgt
    30661 tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac cattaccaca
    30721 aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga atatctgtct
    30781 gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt agctaaaggt
    30841 attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag taaattataa
    30901 gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat aaaaggcgca
    30961 ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga aaaatttgac
    31021 gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc tgtcacttat
    31081 atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata ttacactact
    31141 ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac cggtacaact
    31201 caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact gattggattt
    31261 atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac ttatccagct
    31321 cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta tttgaatgga
    31381 gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc aacagggtta
    31441 gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa acatcgacgt
    31501 gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta ttcatatgcc
    31561 atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc tgccgagttt
    31621 cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt tttaggcgaa
    31681 gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat ttgcagcaat
    31741 tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa atatcgcgga
    31801 cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc tcatgtggag
    31861 cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga ttattaggat
    31921 agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc cctttatttt
    31981 tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc tacagttcaa
    32041 cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg caatagtact
    32101 atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc gccagtttac
    32161 atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa ccgtcaacag
    32221 agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg tctcttatgt
    32281 attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa tgctggtagt
    32341 aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg taaaaataaa
    32401 atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa agaagtaaac
    32461 aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact ataatggaaa
    32521 ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt cttggtcctg
    32581 gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat gtccgtattt
    32641 ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat cagcattttt
    32701 tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca gaagcagtgg
    32761 ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca gtcgcacagg
    32821 aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa ggactagaac
    32881 aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa gaaaaaagac
    32941 aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta catgatatca
    33001 caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa aaactgttca
    33061 tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa actggtgcag
    33121 cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga ttcggagatg
    33181 atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt ggtgtcgcga
    33241 tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg atcgttactt
    33301 gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag ggacataagc
    33361 tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg acaaaagcag
    33421 cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca atctataatg
    33481 ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta cgtgacggaa
    33541 aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc gt
//
LOCUS       DBGZHO010000025        31335 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.025, whole genome shotgun sequence.
ACCESSION   DBGZHO010000025 DBGZHO010000000
VERSION     DBGZHO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.025"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            2..370
                     /locus_tag="ACN3HL_001387"
     CDS             2..370
                     /locus_tag="ACN3HL_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HHC8006275.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            550..1491
                     /locus_tag="ACN3HL_001388"
     CDS             550..1491
                     /locus_tag="ACN3HL_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HHC8006276.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1560..2291
                     /locus_tag="ACN3HL_001389"
     CDS             1560..2291
                     /locus_tag="ACN3HL_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHC8006277.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2435..4615
                     /locus_tag="ACN3HL_001390"
     CDS             2435..4615
                     /locus_tag="ACN3HL_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HHC8006278.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4635..5117
                     /locus_tag="ACN3HL_001391"
     CDS             4635..5117
                     /locus_tag="ACN3HL_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HHC8006279.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5133..5894
                     /locus_tag="ACN3HL_001392"
     CDS             5133..5894
                     /locus_tag="ACN3HL_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HHC8006280.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6025..7359
                     /gene="murC"
                     /locus_tag="ACN3HL_001393"
     CDS             6025..7359
                     /gene="murC"
                     /locus_tag="ACN3HL_001393"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HHC8006281.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7666..8151
                     /locus_tag="ACN3HL_001394"
     CDS             7666..8151
                     /locus_tag="ACN3HL_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HHC8006282.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8144..8827
                     /locus_tag="ACN3HL_001395"
     CDS             8144..8827
                     /locus_tag="ACN3HL_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HHC8006283.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8953..11598
                     /gene="polA"
                     /locus_tag="ACN3HL_001396"
     CDS             8953..11598
                     /gene="polA"
                     /locus_tag="ACN3HL_001396"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HHC8006284.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11643..12479
                     /gene="mutM"
                     /locus_tag="ACN3HL_001397"
     CDS             11643..12479
                     /gene="mutM"
                     /locus_tag="ACN3HL_001397"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HHC8006285.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12443..13072
                     /gene="coaE"
                     /locus_tag="ACN3HL_001398"
     CDS             12443..13072
                     /gene="coaE"
                     /locus_tag="ACN3HL_001398"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HHC8006286.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13124..13456
                     /locus_tag="ACN3HL_001399"
     CDS             13124..13456
                     /locus_tag="ACN3HL_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HHC8006287.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13768..14259
                     /gene="nrdR"
                     /locus_tag="ACN3HL_001400"
     CDS             13768..14259
                     /gene="nrdR"
                     /locus_tag="ACN3HL_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HHC8006288.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14282..15655
                     /locus_tag="ACN3HL_001401"
     CDS             14282..15655
                     /locus_tag="ACN3HL_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HHC8006289.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15655..16581
                     /gene="dnaI"
                     /locus_tag="ACN3HL_001402"
     CDS             15655..16581
                     /gene="dnaI"
                     /locus_tag="ACN3HL_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HHC8006290.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16710..17150
                     /locus_tag="ACN3HL_001403"
     CDS             16710..17150
                     /locus_tag="ACN3HL_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HHC8006291.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17294..17995
                     /locus_tag="ACN3HL_001404"
     CDS             17294..17995
                     /locus_tag="ACN3HL_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HHC8006292.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17992..19113
                     /locus_tag="ACN3HL_001405"
     CDS             17992..19113
                     /locus_tag="ACN3HL_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HHC8006293.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19128..20360
                     /gene="pepT"
                     /locus_tag="ACN3HL_001406"
     CDS             19128..20360
                     /gene="pepT"
                     /locus_tag="ACN3HL_001406"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HHC8006294.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20492..21400
                     /locus_tag="ACN3HL_001407"
     CDS             20492..21400
                     /locus_tag="ACN3HL_001407"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HHC8006295.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21435..21707
                     /locus_tag="ACN3HL_001408"
     CDS             21435..21707
                     /locus_tag="ACN3HL_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HHC8006296.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21718..22764
                     /locus_tag="ACN3HL_001409"
     CDS             21718..22764
                     /locus_tag="ACN3HL_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HHC8006297.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23015..25624
                     /gene="clpB"
                     /locus_tag="ACN3HL_001410"
     CDS             23015..25624
                     /gene="clpB"
                     /locus_tag="ACN3HL_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HHC8006298.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25775..26461)
                     /locus_tag="ACN3HL_001411"
     CDS             complement(25775..26461)
                     /locus_tag="ACN3HL_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006299.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26439..26933)
                     /locus_tag="ACN3HL_001412"
     CDS             complement(26439..26933)
                     /locus_tag="ACN3HL_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HHC8006300.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26953..28173)
                     /locus_tag="ACN3HL_001413"
     CDS             complement(26953..28173)
                     /locus_tag="ACN3HL_001413"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006301.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28320..30155
                     /gene="lepA"
                     /locus_tag="ACN3HL_001414"
     CDS             28320..30155
                     /gene="lepA"
                     /locus_tag="ACN3HL_001414"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HHC8006302.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30249..>31335)
                     /locus_tag="ACN3HL_001415"
     CDS             complement(30249..>31335)
                     /locus_tag="ACN3HL_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006303.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10431 a         5601 c         6716 g         8587 t
ORIGIN      
        1 gatgtttacg aatgaaataa aaatcatgct ttatgtggac gatgtagaaa aaaatgcaac
       61 gttttggaga gcagttggct ttgcggaaaa agatcgtcaa gaaatggatg ggacgcttat
      121 aattgaagta ggagttgagg acagtcaaac ctcatttctg ttatatgatc gagcatttgt
      181 tgagtcccat tcacctggca cagctactag tgccccatct ttgatgtttt acagtaaaga
      241 tatctttgga ctatataaaa aaatgcagac gcaatcagtc acattaggtg atatggtaca
      301 gcttggagaa gaatatgtct ttaactttgc tgatcccgat ggcaactact ttgcggttac
      361 aggtaaataa tagaaataaa gactttgttt ttctgtgcga aacaggaaag cgaagtcttt
      421 ttaattcaaa taataatatt atgtaaacaa aaaactttcc atgcgtaatt atacacaagc
      481 aaataaatcg tcaaatgcga acgccttctt tatactgttt aggaacgaaa agaaggaagg
      541 aagaaataca tggattatca agtactgctt tattacaatt atacaaaaat cgaagaacca
      601 gaggaatttg ccaaaaatca tttagccttt tgcaaatctt tggatcttaa aggtcgtatt
      661 ctagtagctg aagaaggaat aaatggtact gtgtctggaa ccgttgaaaa cacgactgcc
      721 tatatgaaag caatgaaagc tgatcctcga tttgctgata cgatgttcaa gatcgatcca
      781 agcgaaggac atgcctttaa gaagatgttt gtaagatacc gtccagagct tgtaagttta
      841 aagctagaag aggacattga tccaaaccaa gtgacaggtg cctatctttc accgcaagaa
      901 tttaaagaag ctattttaga tgaacagaca gtggtgattg atgcacggaa tgattatgaa
      961 tatgacttgg gacattttcg aggggctgta cgcccagata tacgcagttt tcgagagctt
     1021 ccagactgga tccgcgagca caaagaagaa tttatggaaa aacgggtagt gacctactgt
     1081 actggtggca ttcgttgcga gaagttttct ggttggcttg tccgtgaagg attcaaagat
     1141 gtcggacagc tgcatggcgg tattgctact tatggtaagg atcctgaagt ccaaggagaa
     1201 ttatgggacg gcaagatgta tgtgtttgat gaacggatcg ctgtcgatat caaccaagta
     1261 gataaacaaa tcgtcggtcg cgactggttt gacggaacac catgtgaacg atatatcaat
     1321 tgtagcaatc ctgagtgcaa tcgtcagatt cttgcttcca ttgaaaatga agaaaaacat
     1381 ttaggagcat gtagcataga gtgtgcgaaa catccgcgca atcgctatgt tcaagaccat
     1441 ggaatctctc cagaagaagc agaactgcgg tttacagctt taattaaata gaaaacaata
     1501 gttttgattg tcgaccattt ccaatatgcg ctatactagc gttgaggatg gtgatccaca
     1561 tgaaatcatt gatttatgct attggggatg tccatggcaa acatgagctt tttgaaaaac
     1621 ttattcacta ttatgatcca aagatccatc agcttgtttt attaggggat ctcaatgatc
     1681 gaggtcctcg tacaaaagaa tgttttttat taggaaagca attagtcgaa gaaacaggag
     1741 ccatttacct ccggggaaac catgaagaat attttttgca atttctgcaa tcaccggagg
     1801 actggtatgc gccttatatg agaaatggtg gaaaagaaac gtttgaaagc ctgattcacc
     1861 caggggcatc ggaggaatac tccccaactg aaatctcgat gatgatccaa tcgagatatt
     1921 cagaactgat taaattttta gtccagcgcc ccttgtatta tgaatgggaa aattatcttt
     1981 ttgtccatgc cggtgtggat ttgacaaaga aagactggcg taagacaagt ctaagagact
     2041 ttatttggat aagggaacca tttcatgaag ggaaaaacaa tacaggtaag acaattgtat
     2101 ttggacatac gattacacca atgctccatg gagatatgca gacaacagac ctctggattc
     2161 aggatcataa aatcggaatg gacggtgggg ctgtattcgg agggtcattg catggggttg
     2221 tttttgacaa ggaaggtatt cttcaagata ttgaatatca gaacaacgaa ggaccttggc
     2281 atggaatctg actaatggaa agaatgaagg agctgtgact ttgttgcggc tctttttatt
     2341 tttatagaga atattgtttc tttcagtagt ttaacccagg ataaaaagta tgatagaata
     2401 aagaagcaat ttttagcaga aaagaggcat tttaatgacg gaaaatttga accagacgat
     2461 cattcagctt gtacaaaaag aactttcaga ctatcgtcct aagcagttga ctactgtact
     2521 taatttgtta aatgaaggaa acactgttcc ttttatcgcg cgttaccgaa aagaaatgac
     2581 tggaagtctt gatgaagtcc agattcgtga aatcgaagag cggtatgcct atcttgaaaa
     2641 cttagaaaaa cgtaaaactg aagtgattcg gctaatcgat gaacaaggga aactgactcc
     2701 cgagttagaa gcagaaatca cccaagccgt gaaaatgcaa caagtggaag atttgtatcg
     2761 tccatacaaa caaaaacgac ggacaaaagc aacgattgct aaagaaaaag gacttgaacc
     2821 actcgcgaag tggctgatgc agcttacaga tggagaggtg caatctgaag cagaaaaata
     2881 tattgacaaa gaaaaagaag tctcttctgc cgaagaagcg ttgcacggtg ctcatgagat
     2941 tattgctgaa caagtcagcg ataatgcaaa atttcggact tggattcggt cttatacgta
     3001 taacaaaggt atgtatgtca gcaatgtcaa ggatgagcaa gcagatgaaa aaggcgtata
     3061 tgaaatgtat tatgactttg cagaacccgt ccataaaatg gtttctcatc gaatattagc
     3121 tactaatcgt ggagaaaaag aagatattct gaaagtattc tttcaagtag atgaagcagc
     3181 aattttagct tacttggatc gccaaatagt caaaaatcct gcctctcctt cttcttcatt
     3241 cgtcagagaa gcctatcagg atagttataa acgctttatt cagccagcaa tcgagcgaga
     3301 actgcgcaat gaattgactg aaaaggcaga tgagcaagca atcgctattt tcggcgaaaa
     3361 cctccgtaat cttttgttgc aaccgccact aaaaggtaaa gttgtcctgg gatttgatcc
     3421 ggcttatcgt actggatgta aactagcagt cgtagatgcg acagggaaag ttttagcaat
     3481 cgaagttatt tatcctcata aacctgcagc gcaagcaaaa agagaagctg ctggaccagc
     3541 ttttatccaa ttaattaata aatatcaagt agatatggta gctatcggaa atggtacagc
     3601 cagtcgggaa tctgaacttt ttgtggctga gcagttgaaa tccgccgacc ataaaaccta
     3661 ttacgctatc gtcaacgaag caggcgcttc tgtttactcc gctagcgaaa ttgcacgaaa
     3721 agaatttccg catctacaag ttgaagaaag aagtgctgtt tctattgccc gtcgcctgca
     3781 agatccttta gctgaattag tcaaaatcga tcctaaagct gtcggagtag gccagtacca
     3841 acatgacgtt tctcaaaaac gtttggctga acaattggat tttgttgtgg aaacagcggt
     3901 taaccaagta ggtgtggatg tgaatacagc aagcccgcag ctcttgcagc atatatcagg
     3961 attgaataaa acaactgccc aaaacattgt catttatcgt gaagaaaacg gagaattcac
     4021 cgcacgaact caattgaaaa aagtgccacg cttaggacca aaagcatatg aacaagcaat
     4081 cggattcttg cgagtccctg gtgggaaaaa cattttggac aacacaggta tccatcccga
     4141 aagttattct attgcaaaag aaatattaac ttcagtccaa ctttcagaaa aagagcttgg
     4201 tacagaagaa gcagtagaaa aattgacacg attatccgta gagaaactgg ctgaaagcct
     4261 atcagtcgga gaagaaacgt tagccgatat tttagctggg ctgacacaac ctggacgaga
     4321 tatgcgtgat gagatgccag cgcccttatt acgtacagat gtattgagta tggaagactt
     4381 gaaaccaggg atggaattga ctggaacggt ccgtaatgtc attgacttcg gcgcatttgt
     4441 tgatatcggt gtgaagcaag acggacttgt ccatatatcg aaactcagca aaaaattcgt
     4501 caagcatcct acagatgtcg tgtcagtagg agatatcgta acagtttgga tagaacaagt
     4561 cgatacgaaa aaaggtagaa tcagtttgac gatgctttcc ccttatgaag agtaacaatg
     4621 aggagtaaca aaaattgaca caagaagaac tgcagcagtt agtagaagag atatcattaa
     4681 aaagcttcca gcttcctttc aagcaccaag caatgttcaa tccacgctta cgtacaactg
     4741 gcgggcgcta tcatttaaac gatcatcatt tagattttaa tgcgaagcta tttgaagagt
     4801 cagacgaaga gacgattgca ggaatcatca aacatgaact ttgccattat catcttcatc
     4861 tagctggaag agggtatcag cataaagata tggatttcaa gtatcttttg aaaaaaacag
     4921 gagggttgcg ctatgcacca gccttgacga agaaacagat aaagatggag tattatcgat
     4981 gccaagattg ttctgccacg atctgccgca agagaagaat cgatgtacgc aaatatcgtt
     5041 gtggaagatg tcatggagaa atcaaatgga ttgagacaaa aagagaagac tttaatgaag
     5101 cacaaaaaat cagatgaaag gatagaaggc ctttggaaaa aagtgagcag aggaatctaa
     5161 aagactggaa tcagctatta aattttttag ccgcacctga agagggaaat tttgaggaac
     5221 tgacggcacc tacacttatt ttagctggaa actgtcttcc tatcttagct gataaagcag
     5281 cacaaatgta tttaaatggc caagtagatc aattgttttt ggtcggaggg gtggggcatg
     5341 cgactagaat cctttatgag aattttgaaa agcaaggatt tcattttgaa gatggcatga
     5401 gtgaaagtga aatctgtcgt cagtatctaa aagaagtcta tgatttgccc gataaggctt
     5461 ttctgataga atcgaagtct acaaattctg gagagaacgc cactttttca ctggagattc
     5521 ttcattcctt aggagctgta ccagaaaaaa tcttattgat gaatgatccg acactgcaac
     5581 gcaggactcg agcaactttt gagaaagtat ggcaaaatga acaaactatt ttcgcgaatg
     5641 ctgtgccatt tgtgccggaa atccttcact tttctgaaga gatcatcttt acagcaaaag
     5701 aactgaatca tcaatggcct aaggaatatt tccatgcgct agtattagga gaaatggaac
     5761 gtctccatga cgatgagaac ggctatggtc cgaaaggaaa agattttatt cctcacattg
     5821 atatatcaga ggaagtttgg tcttcttaca ccagaattaa agagtcaata aaaacggatt
     5881 tttctcgtac ttgaccattt tagcaagcga atcctccttt ccaaataaat ttggttgaaa
     5941 ttttcaatcg tttataagat aatgaggagc gtgttgaatg taatagctaa aagaatggac
     6001 gctagataag agaagaggat tcaaatggaa aatcaaaata aattgtatca ttttgttggt
     6061 atcaaaggtt caggaatgag ctccttggct cttgttttac atgaacaagg tctaaatgtc
     6121 caaggatcag acattgaaaa atatttcttt acacaaagag atttagaaaa agcaaatatc
     6181 acgattctgc catttaacgc agataatgta aaaccaggga tgacgatcat tgcaggaaat
     6241 gcatttcctg attcacatga agaaatccag cgagcaaaag aattaggttt ggaagtgatt
     6301 cgctatcacg actttattgg tcattttatc caaaattata cgagtatcgc tgtaacaggc
     6361 tctcacggaa aaacaagtac gactggactg ctctctcatg tattgagtgg tgtccgtcca
     6421 acaagttatc taattggaga tggaacagga catggtgatc cgcaagcgga attcttttca
     6481 tttgaggcct gtgaatatcg ccgtcatttc cttgcctatt caccagacta tgcaatcatg
     6541 accaatatcg attttgatca tccggattat tatacaagta tcgacgatgt atttacagct
     6601 ttccaaacaa tggctggaca agtgaaaaaa gctatttttg cgtatggtga cgatgcttat
     6661 ttacgcaaat taaaagcaaa tgtgccgatt tattattatg gtgtcacaga aaacgatgat
     6721 atccaagcac gaaacatcga acgcacaact tctggttctg cttttgatgt ctatcatggg
     6781 gatgaatttg ttgggcactt cactgtacca gcattcggta aacacaatat cttaaatgct
     6841 ttaggtgtta ttgcagtagc ttatttcgaa aaactggatc tgaaagaagt tgcagaagaa
     6901 atgctgactt tcccaggagt aaaacgtcga ttcagtgaaa agatcgtagc agacatgacc
     6961 gtagtcgatg attatgcgca tcaccctgca gagatcaaag caacgattga tggcgcacgc
     7021 caaaaatatc cagataaaga aataattgca gttttccaac cccatacgtt tacgcgtacg
     7081 attgcattga tggatgaatt tgcagaagca cttgatttag ctgataaagt ttacttatgc
     7141 gatatttttg gttcggctcg ggaagaacaa ggaaacgtta agattgaaga ccttggagcg
     7201 aaaatcaaaa aaggtggaga agtcatcaaa gaaaataatg tatctccatt gttagattat
     7261 catgatgcag tagtaatctt catgggtgct ggagatgttc aaaaatttga acaagcgtat
     7321 gaaaaacttt taagcagcac gacgaaaaat gtactgtaat acaattactg cagtgtcctt
     7381 ataaaaatag aaagaggggg agtggcaaaa atcttgccaa gccccctttt ttgcaactta
     7441 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaatcaaa tcaaaaacat
     7501 gagaagctgt tttttcttgg ctgttcttat tatttgatgc aggacagctt tttcacgacc
     7561 tctgtaaact ataggaatct gttaaatcaa gggagcagaa cttgcctttt acgctacttt
     7621 tggtacaata atgtatgatt aaaaataaac tggagggttt ctatcttgaa cataggtaag
     7681 ccgagaaaac taggaaaaac aataaatgaa atcgaggaag gcgactcgtt atccttaaca
     7741 gaatctattg aagataacca gcttttgctg tatttgggat tgacgaatga tgcaaatcct
     7801 ttgtatatcc aacatgactt tgcacaaaaa acagaatatc aacagccaat cgttccatca
     7861 gtgatgctga tggggatcat cacaagtgca atttcaaagc atcttcctgg accaggatca
     7921 catgttgtca atttttctgt caattttatt gaaccggttt tccattatga aacactgact
     7981 tttcagtttg aggtcataaa agtagataag atgaaggatg tggtgacgat ttctgtagaa
     8041 gcggagaata cgaacgaaga tcgtgtgttg gatgctgtcg ttatggtcca accgccacaa
     8101 gttcctgaat tggaaatagc aatcgaaagt gaaggtgaat tgaatgaata atccaagtac
     8161 atcaatgtca ggtatcaatc gtttttatgc aaaagtttat ggatttttag gtatgggact
     8221 tgcccttagt gcagtcactt cttacttggc tctttgggta tttcctttgc aattagcaac
     8281 ttttatcaat aattttccac taggctttgt gggtctgtgg atcgttgaac tgattttagt
     8341 aatggttcta ggcgtaaaag cacaaaagaa tccgagctta gcaatcggtg gatttattgc
     8401 ctactctctt ttgaatggca taacattagc ggttactctt gcatactacg atattggaac
     8461 agtaacgcaa gctttcttga cagctacttt gatgttcatg gggatgtctg ttgtcggagt
     8521 aacaacaaaa agagatctta gcggggttgg aagagcagga caggcagctt taatcggagt
     8581 gatcattgca ctagtcttga acatcttcat tttgagaagt agcgtagttg agctgttcat
     8641 ctccctactg ttagtcgtca tctttgcagg gattacagct tatgataacc aaagcatccg
     8701 taatatctat gtccagacaa acggaacagc acatagtgga attgctgtat tcatggcatt
     8761 gaagctgtat ttggacttta tcaacttgtt cttggcgttt ctgagaatct ttggacggaa
     8821 caactaaaaa agaaaaaaat tcatcagttg gggctatacc gaattatttg gtatggtccc
     8881 gctttttctt ttcgcattcc gcaggattct ttgttagaat gaataagaac tttacagtaa
     8941 ggagttaaga agatgacaaa aaataaatta ttactcgttg atgggaacag tgtggctttt
     9001 cgcgcattct ttgcgcttca caattctctt gaacgtttca aaaatagaaa cggtcttcat
     9061 acaaatgcaa tctatgcatt caatacgatg tttgaaaatg ttatgcaaaa agagcaaccg
     9121 actcatgttc tggttgcgtt cgatgcagga aaaacgactt ttcggacaga aatgtatgcg
     9181 gagtacaaag gtggaagatc caaaacacct ggcgaattca aagaacaaat gccatatata
     9241 cgtgatttgt tgacaggact aggggtacag tattacgaat tgcccaatta tgaagcagat
     9301 gatattatcg gtactttggc agaaaaagta gacaaagatc aatttgatgt cgtcgtgctt
     9361 tcaggtgatc gggatttgac tcaattagct agtaaagaag taaaagtgga tatcactgta
     9421 aaaggtgtca gcgatatcga aagctataca ccagaacatg tagcggaaaa atatgatggg
     9481 ttgacgccaa aacagattat tgacatgaag ggactagccg gagatgcctc tgacaatatc
     9541 cccggtgtga ctaaaatcgg tgaaaaaaca gctatcaagc tattgaaaca atatggctca
     9601 gtcgaaggaa tttatgaaca tatcgatgaa atgaagcaaa gcaaaatgaa agaaaatctg
     9661 ataaatgaca aagagcaggc tttcttatcg aaaaaattgg cgaccatcaa tacttcagcg
     9721 cctgtggatg tctctatcga ctcattgaag tatgaaggga aaaatctcga taaactcgtt
     9781 ccgttttata aagaaatgga tttcaatcag ttcctttcta aattgaatat cgtagaagaa
     9841 gaagtaaaaa tggatgatat tttgtttgaa gtcgttcatg aattcaaaga ggaaatgttt
     9901 actacggata tggcgttgta cgtggaaatg atgggcgaca attatcatac agaggaaatc
     9961 gtcggagtag cgtgggggac agaaaagaaa atttatgtca cgaacgatct atctgtattc
    10021 gaaaaccgag cgttccattc ttggatcact gatccgactc ggctgaaaaa agtatatgat
    10081 gcgaaacgaa cttatgttgc tttaaaccgc tatactggaa aaacgaaagg aatcgatttt
    10141 gatgtcttgc taggtgcata ccttctcgat acgaatgaaa aaagcacaga tatcgaagga
    10201 atagctgctc attacggata caacgatatc caatcagatg aagctgtata cggcaaaggg
    10261 gcgaaaaaag gtttaccaga agaagaggaa ctcttttttg ctcatttagc gcgaaaagta
    10321 gctgcaatca atgcgttgac accaaaattg agccaagaac tggcagaaaa aaaccaagaa
    10381 gatcttttcc ggaaaatgga actgccattg tctatcattt tggcagagat ggaaataagc
    10441 gggatcaaag tagatgcgac tcgcttacaa gaaatgaagg gcgagttctc tgctcgctta
    10501 agagagatcg aacaaaaaat ctacgaagaa gccggcgaag aattcaattt gaattcacca
    10561 aagcaattag gagtgatctt atttgaaaaa atgggattac ccgttatcaa aaaaacaaaa
    10621 actggatatt ccacagccgt agatgtactg gaacagcttc gtgaacaagc accaatcgta
    10681 gaggatatcc tcacctatcg tcaaattgca aaaattcaat ctacctatgt cgagggactg
    10741 ctgaaagtga tccaatcaga tggaaaagtg catacccgtt atgtccagac attgacccaa
    10801 acaggacgat taagctctgt tgatcctaat ttgcagaaca tcccgattcg attagatgaa
    10861 gggagaaaga tacgtcaggc atttgttcct agagaaaaag actggctgat ttattcttct
    10921 gactattcac aaatcgagtt acgcgtactt gcgcatatct caaatgatga acatttgaaa
    10981 gctgccttcc tagaaggtca agatatccat gccagcacag cgatgcgtgt atttggaatc
    11041 gaaaaggcag aggatgtcac accaaatatg cgtaggcagg caaaagcagt gaattttggt
    11101 atcgtgtatg gcatctctga ttacggactt tcacaaaatc taggaatcag ccgaaaagca
    11161 gcacagcaat acatcgatac gtactttgaa aaatacccag gtgtcaaaga atatatggaa
    11221 agaatcgtac gcgaagcaaa agaccaaggc tacgtcgaaa cgctgtatca ccgccgtcga
    11281 tatctgccag acatcaattc aagaaattac aatatccgtt cttttgcgga acgaacagct
    11341 atcaatacac caatccaagg aagtgctgct gatattttga aaatcgcgat gatcgaattg
    11401 gataaacgat taaaagaaac aggtcttcaa gctacgatgc tgttacaagt tcatgatgaa
    11461 cttgtcttcg aggtaccgga aaaagaactt gaatcattag ataaattggt gaaggaagtt
    11521 atggaacaag ctgtttctct tcatgtacca ctgatcactg acagcagttg gggaaaaacg
    11581 tggtacgaag caaaataaac attgtttaag acagagcaat ataatgaagg tgaaaagaaa
    11641 aaatgccaga attaccagaa gtagaaaccg ttcgtaaagg attggaacgg ttagtagtag
    11701 gaaaaacgat tcaaaaagtt caggtcttgt ggcccaagat catcgagcaa ccagagacac
    11761 ccatctttga ggcttctctt gttggcgaaa ccatccaatc cattggacgt agagggaagt
    11821 ttttaatttt tcatctcgat cattgtgaac tgatctcaca cttgcgaatg gaaggaaaat
    11881 atcaatttac gaaagaaaat acaccaatcg ataaacatac gcatgtactt ttcttttttg
    11941 aggatggaag ccaacttcgc tacaacgatg tacgaaaatt tggtcgtatg acaatcgtcg
    12001 aaaaaggagc aagtgcaact taccgaggaa tcatgaaatt gggacctgag cctttgccag
    12061 atagcttctt attagcagat ttcgcaaatg gactgaaaaa gtcccacaaa gcaatcaagc
    12121 cattgctgct agaccaacgt ctagtgactg gtctaggtaa tatttatgta gatgaagcat
    12181 tatgggaagc gaagatccat ccagaacaac cggcgaacac actgcgcccc aaagaggtag
    12241 aacaattacg tctatcgatc attgatgttt tggatcgtgc aatagaagcc ggaggtacca
    12301 cgattcgcag ttatttgaat gcattaggag aatcaggcgg atttcaagta gcactgcatg
    12361 tctatcagca aactggcaaa ccatgtatac gttgtggaac gccgatcgtg aaaacaaaag
    12421 tggcacaaag ggggacgcac tattgtccga attgtcaaag gctaaaaatc gcaaagtagg
    12481 atttgtttta ggtttgacgg gtggaatagc taccggtaaa agtacggcag ccaaagtctt
    12541 tcagtctcat ggatttcctt tgatcgatgg cgatgtgatt gccagagaaa ctgttgagcc
    12601 tggaacgctt gctctgagga aaattgtatc agtgtttggc caagaggtat tgcagcctga
    12661 tgggcaacta gatcgaggga aacttgggat gattgttttt ccatcaaagg aaaaacggca
    12721 aaaacttgat cagctattag atccgtttat ccgaaaagcg ataaaagatc aaatcgcctc
    12781 tctaagttcc aatcatcctt tagtaattgt agatatccca ttgctctacg aaggtcatta
    12841 tgaccactat atggatgcag tagctgtcgt ttatactacg ccagaaactc agcttcagcg
    12901 tttgatgaaa cgtaatcaac tgacgctaga acaagcgcag cagagaatta gtagtcaact
    12961 tccaatcgaa gaaaaaaagc agcgtgcgga tattttgttc gacaacaatg gaacaaaaga
    13021 aaaacttgtg ggacaaatcg aaaattggct ttttgctaat cgctttcttt gagtatctgt
    13081 gtcaattttg ctatcctgag tatatagaaa gtgagggata gcgatgggat cattaaaaaa
    13141 tcaaaaggat aaagtcgtag gtaacgcaaa agaaaaaatc ggcgagatgc tcaataaaga
    13201 aaatctaatc gatgaaggtc gtacgcaatc agaaacagca gaagaaaaag aaaagcagta
    13261 ccaagcaaga atcgatgaaa tagaagacca gcaggcagaa gaagaagcga agcggcaaga
    13321 tttgactcaa gaacgaaaaa atccgacacc tgatcgtagt aaaacaccgc tcccagaaag
    13381 tgaccacatt cccgatgagc aaaaaatcga ggaacagcga atgaaacact atacaggaat
    13441 cgaagagaag ttataaaata gtaaaaaatc gagatgtgac ttgaagcaga tgagaaggtg
    13501 ttcatctgct tcaagttttt tgtgctagat gactaaatca gcttttgtgt aagttatttc
    13561 tcagtaatca aggtgatcag tattggaaaa ttgaaattta gtaaggacag gggacacaat
    13621 tacgcatgaa agtagaaaaa attgttctta tatccgtgtt ttttgggtag gacagtcgcg
    13681 tttgtgattt gtttcgtgtt ataatacaac tagttgtaaa gaaagacaca tcctttatat
    13741 aaaatgcgat gcaagaggtg agacaaaatg agatgtccca gatgtcaaca taataattca
    13801 cgagtaatcg acagccgtca agcagatgat ggacgtgcga tccgtcgccg tcgcgaatgt
    13861 gagaattgtt cgttccgatt cactacattt gaacgaattg aagctgctcc gttattagta
    13921 atcaagaaaa acggggaacg cgaagagttc aatcgcgata aaattttaag aggactcatc
    13981 cgttcagcag aaaaaagacc tgtagctatg gaacaaatgg aacaaatcgt caaccatgtc
    14041 gaaaaccgcg tacgcagtct cggagaaaac gaagtatcga cgaatctaat tggtgaatat
    14101 gtgatggaag atttagttga tttagacgaa atcgcttata ttcgttttgc aagtgtttat
    14161 cgccagttca aagatatgtc tgttttctta aaagagttgc aagatatcgt ggataaagca
    14221 aaagaaaata ataaagagaa taataaagaa aacaattaag aaacaaaaag gaggcatttc
    14281 cttggaaaat gcttggaaag agcttcaacc aaaaaatatt taccaaggaa gaaaagcggc
    14341 tccgctgaga gaagacagca agaacgcctt gctgtatctt tatcagccac taatcggcgg
    14401 agaagccttg agtatctatt tcaccctgtt atcagaaatc tctcaagaat ctggcaaagg
    14461 tcctgaaggg atgcatgcag atctgcttag tagtctaggc tgcggtatcc cgcaatttta
    14521 tgatgcaaga aaaaagctag aaggaatcgg cttactggat gtttatttta aagaagatag
    14581 tgatctggga cctcgtttta tttatgagct gttagaacca ctcattccta aagcattttt
    14641 caaagactct gttctggctt ttcttcttct ggaaaaagtt ggtgaacgac gattccagaa
    14701 gcttacccaa ttctttgaac ctaaaaggca tacagcagag ggatatcaaa aaatcacaaa
    14761 aaaattttta gatgtttatc gcttcaatga agcagtgtac gctgctaatc aagaaaacat
    14821 cgaatcgctg aataaatctt ttgaagaatc tgaatcagta gcattacttg aagcagattc
    14881 gacattcgat tggcagtttt tgaatgattg gctggcaaaa aaacatattg caagtcttga
    14941 tgatccaatc atcaaacaag tcgacatgta tcatcagctt tacggtttcg atgaattgac
    15001 acttggcgaa ctgatcagtc aatcttatga ctttagtgaa caaaaagtat ctgaaaaaga
    15061 actgcaaaaa gccattttgg caatgcagag acgtccggtg aagcaaacaa aagaaacagt
    15121 tgcggtttct gaaaacagta atgaaccctc gtcaaacgaa catttgacaa acgcagcgct
    15181 tcagctgata aaagaagcac agagcattcc accgatgaaa tatctggaag caatcaagtc
    15241 agaaaaaggc ggatatgttt ctaaacaaga aaactggtta ctgcaagatc ttgtttctca
    15301 atcaggtctt tccagtagcg tgatcaatgt tttgctgaat tatgtactag tgatcaagaa
    15361 taatgctagc ttaaatgcca gttatgtaaa tacagtggca aatgaatggg cacaaaagaa
    15421 aatcgccaca gcagaagaag cgatccagca cattcggcaa ataagtaatc aagcaaaaca
    15481 atcaaaacaa aagaagcaaa caaattatca aactggcaag cgaaatgttc gacgggaaaa
    15541 gcttcctgat tgggtcaacc agccaaaaga tgaaaaacag atcagcagcg agaaaaaagc
    15601 agagattgac cgccgtttta aagaatacct ggcaaaaaag gagggtgata tctagtggaa
    15661 gacgtaggca aagaattgaa gaggatcatc agcaaacgca attatcaaga aaagtatgct
    15721 gaaatgatcg ctgaagtctt aaatgatgcg gatgttcaag cttttctaag cgcacaccaa
    15781 gaagaattga cacaagcgga tattgaaaaa agttacgcta aattgtatga attcgtgcaa
    15841 gaaaagcgta aatatcaaaa aaacgatcca acgatgatcg ctcccggcta tgagccgaag
    15901 ctgacgttga attttcatta tgtggatgtc acttatgtac caacggaagc attgttagca
    15961 cggcaaagac aagaagaaat cagaagccga gtaaaagcaa tggatatgcc aaaagatatt
    16021 caatcggctt cttttgaaaa ctttgaacgt acagatggac gaggatatgc gagcttagaa
    16081 gccctagatt ttgtagagaa atatactgct gatccaaaag ggtatcataa aggactgtat
    16141 ctagtaggaa gttttggtat tggaaaaaca tatttattag gagcaacagc gagagaatta
    16201 gcgattgctg gattcaccac gacgctagtc cattttccga catttgccgt tgagatgaaa
    16261 caggcaatcg gaaaagatca agtggcagaa aagttagatg cagtgaaacg ttcacctatt
    16321 ttgatgatcg atgacattgg tgcagatgcg atgagtagtt ggatacgaga cgaagtattc
    16381 ggtgttatcc ttcaatatcg gatgcaggaa cagttaccaa ccttcttctc atcgaatttt
    16441 acaatggatg aattggaaca gcatttgtcc gtcactcaac gtggagatga agagccgcta
    16501 aaagcgaaac ggataatgga acgcatacgt tatttgacaa aagaaatcga aatgactggt
    16561 cgcaaccgac gcaatggttg aacagttgac aagtccaact gacatttgac ctagtagtaa
    16621 aagcaggtca gcgaatcatt atatggacag aaatgaccgg agacaatcac cgcaacaagt
    16681 aatgcagaaa cttaaacgga ggatttttta tgagggctat tttttctagt atatctgtag
    16741 ttggtctatt ttttctttta gcaggctgcg gtagcgcaga tagcaacaca ggttctgttg
    16801 attcgattga tgcgggtcaa acagtaaaaa caagcagtac gaaaacggag agacaaagca
    16861 tatttgtcgg aacgattgaa agtatcactc aagtagaagc agaagaagaa acgcttcagt
    16921 tgaaactcgt cgatgtcatg gccaaagaag atccagcgaa tatgggaacg tcattcagca
    16981 atgacggagt gatcttaaat gctactgctg aaaaaataag cgtggacata aatgaattga
    17041 aaatcggtga caaagtccaa tttacattag ttgagatgcc gatcatgacg atgtctatcc
    17101 caccgcaagt tcctggagat tcgattattg atgtttcatt gaacaaataa ccaataacat
    17161 tttttcaaaa ataagaaaat gttgttttat agaacgaaaa ggtatatttt ttaaggagat
    17221 atgggaattt ttttattcct agtctcctta ttttatttgg aaaatgctat aattatctag
    17281 aaggagtgaa gctatgaacc atttagattt atctcagcgc ttagccgcag tgggtgactt
    17341 tgtccctgaa tccgctcgtt tagcagacat tggatcagat cacgcttact tacccgttgc
    17401 attgatatta agaggaaaaa tcgaatatgc agttgctggt gaagtcgttc aaggtcctta
    17461 tgaatcagca cgtaagcaag tcaaaaaaga tggattagaa gaccgtatca ccgtacgcct
    17521 tgcaaatggt ctagatgcta tccagccaca agatggtatt acagctgtca cgattgcggg
    17581 tatgggaggt tcactgatcc gagatatcct agaagctggc aagttgaatc aacgcttaag
    17641 cggacaagaa cgtttgatcc ttcagccaaa catcggagag cgtacattac gatcttggct
    17701 gcaagaaaat cagtataaaa tccaatcaga aaaaatactt gaagaaaata aaaaaatata
    17761 tgaaatcatt gtagccgaaa aagaacaaaa accagttact tacaatgaaa tggagctgat
    17821 gttcgggcca tttctgcttg aagagaaaag tgagatcttc aaatcaaaat ggacaagaga
    17881 gcttcaacaa agaaaagcta tccgtgaaca gctcaaacaa gcagctaatc aagaggcacg
    17941 tcaaaaacaa atcgagcagg aaatccaaat gattgaggag gttttaaagc catgacaatc
    18001 agcggacgca ctttcatcca aaagtttgaa agctattgtc ctcagtggct agctgaagaa
    18061 ggagacccag tcggactgca tatcggaaca ttggataagc caatccaacg agtaatgatg
    18121 acattagacg ttcgtccaga agtggtcgaa gaagcaatca agaaaaaaat cgatttgctg
    18181 attgctaaac atcctccaat ctttcgtcct gtaaaacggc tggttactga tcagccacaa
    18241 gaaaaaatgt atgcagattt gttgaaacat gatattgccg tctatgcagc acacacgaac
    18301 atggatatta tttgggatgg actgaatgac tggttttgtg aacttctcgg tattgaagtg
    18361 gagagttatt tagtaaagac tcatgagatt cattataaaa aactggccgt ttatgtacct
    18421 gtggatcatg cacagaaaat gcgtgaagta ttagctgcag ctggtgctgg tacacaaggt
    18481 gattataccg gtacaagttt tacctcgatt ggacacggtc gatttactcc ggaagctggt
    18541 gcacaaccag cgattgggaa agtagggaag acagaacaag ttcaagaggc aaaagttgag
    18601 gttattttgc cggaaactat cgaaaaacaa gtgattcaag ccatgcggtc agctcatcct
    18661 tatgaggaac ctgcttatga tcttttcgct atagatgaac cagtcgaaat gtttgggtta
    18721 ggacgagtag gtgaattgcc gcaagaaatt tctatagagg catttgtaga acaagtaaaa
    18781 gaagcgttcc aactagatgg actgagaata gtccagccaa aaaatgcaaa atcctctgtg
    18841 aagcgcattg cgatttgcgg tggaagcggt gaaaaatttt atccgcaagc aatcgcccaa
    18901 agagcagatg tctatatcac gggagatatc tattatcata cggctcatga tatgcaaagc
    18961 gctgggttga ttgcaattga tcccggtcat tatattgaat cgttatgcaa gcaacgattt
    19021 atcgagaaat ttgaatcttg gaaacaagaa gaaaattggg atattaactt tttcgtttct
    19081 gaaacaaata caaacccatt tcaatttaat taaaaggaga gaatactatg tacgaaaatc
    19141 ttttgccacg ttttttacga tatgtcaaaa cagaaacacg ctccgatgca acaagcaaaa
    19201 cgactccatc gactcagaca caagttgctt ttgcgcaaga attgaaaaaa gaattagaag
    19261 agttaggctt agctgatgtt ttctataatg aagataacgg attcgttatg ggaacattac
    19321 caagcaatgt tgatcatgaa gtgcgttcca ttggatttat ttcccacatg gatacagcag
    19381 attttaatgc agtaggagtc aatccacaaa tcattgaaaa ctatgatggc gagtctacga
    19441 tcgtactaga tgcggaagaa cgctatacat tgaatacaaa agattttcca aatttgaaaa
    19501 attatgaagg ccacacattg atcacaacag atggcagtac attactggga gcagatgaca
    19561 aatcagggat tgcggaaatc atgactgcaa tggagatctt gatcaataat ccttctatcc
    19621 ctcacggtac catcaaagtg gcttttggtc ctgatgaaga aatcggtgtc ggagcggata
    19681 aattcgatgt tgagcaattc gatgtagatt ttgcttatac agtcgatggt ggtcctttag
    19741 gtgagttgca gtatgaaacg tttagtgctg ctcaagcaaa tattacgatc caagggaaaa
    19801 atgtacatcc agggacggca aaagatacaa tgatcaatgc tctacagtta gcaatcgatt
    19861 ttcataatca gcttccagcc gatgaagttc cagaaaaaac ggaaggatac gaaggtttct
    19921 tccatttgat ggcattggat gggaatcctg aagaagcttc tatgagttat atcattcgcg
    19981 atcatgatcg tgaaaaattc gaagcacgca aagcacaaat cacacatatc caagaagagt
    20041 tgaatcagcg atttgatcaa gaacgaatca aagtagatat gtatgatcaa tattacaaca
    20101 tgaaagaaat cattgaaaaa gatatgagca tcgtggaatt agcgaaacaa gcaatgatcg
    20161 agcttggtat ctctccagtg atcgaaccag ttcgtggagg aacagatggt tcaaaaatct
    20221 cttacatggg tattccgacg ccaaatctat ttgccggagg agaaaatatg cacggacgat
    20281 tcgaatttgt ttctttacaa gtaatggaaa aagcaacaga cgtgattgta aaaattgcag
    20341 aattgaacac aaagagttaa aatcgaaaaa gaacagctta tgacaaggcg ttcgtcccaa
    20401 tgatggaatg tcatctgtct aaggctaaag ggcaggacaa tggaattggt tgtcccgccc
    20461 tcttttttga agagtaaata ggaggtaaag aatggaaaag ctgctagttt tttataacaa
    20521 aagttcaggg aaagatgagg gtgagaaatt agcacgctgg tttcaagatt atgtaaaaga
    20581 aaagcagcca gaattatatg tagaactagc tgaaactggc ccatcgattg atgatgcgga
    20641 attagtcaag aaagcagaag ccatagaagc tgatacttta gtaattatag gtggagacgg
    20701 cacgattcat catatcgtcc aagcgttcca aaaaacatta tctcaatacc atgtcggatt
    20761 acttccaggt ggaactgtca acaaccttgc acgtgttctt gagattcccc tcaaaaaaga
    20821 agaagctgct gacgtgatcc tggaaggcaa tgtacggaaa atagactatg gtcaagtcaa
    20881 tgatgaagtc attatctcta cactgacaat cggaatctta gcagatacag cagtttggat
    20941 cagtcaagaa gaaaaacagc gttacggctc gtggatcttt atcaagaagt tttttaagtt
    21001 attgctgaag aagaaaaaat atcatttgga tttagaaaca gacgaggagc attggaaagg
    21061 aaaatcccaa ctgttgacag tcacgatgtc taactccgtg ggcggtttta caaattttga
    21121 cgactcagcg accctagatg atggaaaatt tcatgtaacg atcgtacctt ccttagatat
    21181 tttccgattt attttttatt tgcctagaat catgagaggc aaattctata cgatccccgg
    21241 cattacttat ttcacagcca aacgcatgaa aatccaagcg caggaaaaat ctgtgggcac
    21301 tcgaacggat ggagacacga cagatgatct tccagttgaa ttatctgttg tatcaaaagg
    21361 attaacagtt tattcaccaa agaaagaaga aaaagcttag aaatagtagt taacagaaag
    21421 ttggaagaag agtaatggat gtattgttac acaatccttt gtggttttac cttttcattg
    21481 tgaattttta cttattttgt ctgatggggt atgataaaca tcaggctaga actagcggct
    21541 ggcgtgttcc tgagaataat ttgatatttg tcagcctgtt aggcggtggt ttgggaggat
    21601 tgatctctcg aaaagttttc catcataaaa ctcggaaaaa gaagtttact ataggattcg
    21661 ctgcaggtgt acttgttgat ttgattctca tttatttttt ccattaagga gcaggagatg
    21721 tcgtctaaag gaacgaaaac taaaatcatt ctgaatctgc ttttgctgat tgtgattttt
    21781 gccattattt attatttaat caatcaatca tttgcagata tctttgccga attgctgtct
    21841 accagtgttg ttgttttggc agcggctgtt atattaggga cagtttacca aatcgctgaa
    21901 gggcgctcaa tcaaagaaat tgctgaacct ttcgcgccga attttacaac gaaagatggg
    21961 ttcttgacct ctagctatat tgcgttttac cgaatcgttt cgtttggtac aggaacgctg
    22021 atctcggaga tttattttta taacaaaaaa ggaatgaagc tatcccaggg agcaggggtg
    22081 acagcactcc atatgattat gtacaaactg gcagtgatca cttatgcatt agctggcttg
    22141 gtcatccaat tctctctttt ttattctaat ggtccatcaa tgatctggtt tatcatcgct
    22201 ggtatccttt tgacgatcgt gattgttgcc tttttattgg cgatgtccgt cagcttgaat
    22261 gttcaaatat tttttgtcag cttatcgaat aagttattta aaagtgagcg tttgcggaaa
    22321 tgggtggata catgcaatca gcagatctac tctttaaggg aaacggtcca aaccattatc
    22381 caagacagga ctgcgctatt gcggatttat ctatggaata tgttaaaact tgtattttgg
    22441 tatgtacttc cttatttgat tctgattgaa aaccatccta aaatagattt tctactgacc
    22501 atttcgttta tcagctttgc agtagtgctt tcaggggtta ttcctacgcc tgctggtatt
    22561 ggttcctttg aatttgtcta tttgttatta ttcagaccag ttgttggaac agttgacgca
    22621 gtttcttcgc ttttactgta tcgtttcagt tcctttatct tgccatttct ctatggattt
    22681 gtgtatgtga ttgctgaacg gcgaagagtg atcaaagaag aaataataga agtaaaaaaa
    22741 gagaataaag aaaatcaagg gtaggtcttt tataagatct acccttttta tcaaatcaaa
    22801 gaaaaacgtt atggataaga taattttacg tttgtttggc tcttttttta tatacataca
    22861 atcaattttg tttttttaag atttatataa gtcgagaaaa aaagtcaaaa aactatgtgt
    22921 atattttgac caaaattgac caaagcgata taatagtttt tgtaaagatc aaagaaataa
    22981 gtgatcttac ctttaattag gagggtatac ctgtatgaat attgagaaaa tgactacgac
    23041 gcttcaagaa gcgattgctg aagctcaaca gattgcggtc actcgaaaac atcaagatat
    23101 cgacattgcc catgtatgga aaatcttttt acaatctaat cattttggtc gaaatttcta
    23161 tacggatgcc ggattggatg tcgaatcttt tgaacatgaa attgatcgtc tactggatga
    23221 gtatccagtt gtttctggtg gaaacgtcca atatggacaa aacctcagcc agaatttctt
    23281 tcgattattg aatgaagcag accaaatacg tgaaagcttc ggcgacgagt ttctttcaac
    23341 ggaagtcgtt attttagcgt tgatgaaatt aaaaaattat ccgttaactg tttatttgaa
    23401 taaaaacgga ttatctgaaa aagaattgcg taaaaacatc gaagagatga gaggaggaga
    23461 aagagtgacc tcacaaaacc aagaagaaca atacaaagca ttagaaaaat acggcgttga
    23521 tttagtacag caagtcaaaa gcggaaaaat ggatccaatc atcggtcgtg atgaagaaat
    23581 ccgtgatgtc atccgtattc tttcacgaaa aacaaaaaat aatcctgttc tgataggaga
    23641 acccggtgta gggaaaacgg caatcgttga agggcttgct caacgtatcg tacgcaaaga
    23701 tgtgcctgaa aatttaaaag ataaaacgat tttttcatta gatatgggtg cattgatcgc
    23761 tggagcaaaa ttccgtggtg aatttgaaga aagactaaaa gcagtcttga aagaagtcaa
    23821 aaaaagtgat ggacgtatcc tcttgttcat cgatgaaatc cacaatatcg taggggcagg
    23881 aaaaacagaa ggaagtatgg atgccggaaa tctgttgaaa ccaatgcttg ctcgcggtga
    23941 attacatttg atcggtgcca caactttaga tgagtaccgt caatatatgg aaaaagacaa
    24001 agcgttggaa cgtcgctttc aaaaggtatt agtcaaagaa ccaacagtgg aagatacgat
    24061 cagtattctg cgtggattaa aagaacgttt tgagatccac catggtgtta acatccatga
    24121 caacgcatta gtagcagcag ctactttatc tgaccgttat attactgatc ggttcttacc
    24181 ggacaaagca atcgatttga tcgatgaagc cagtgcaacg attcgggtag aaatgaactc
    24241 tatgccaacg gaattagatc aagttactag acgtttgatg cagttggaaa tcgaagaagc
    24301 tgcactgaaa aaagaatcag atgatgcaag taaaaaacgc ttgaaaaatt tgcaagaaga
    24361 attagctgaa cttcgtgaag aagcaaatgc gatgaagatg cagtgggaaa cagaaaaaga
    24421 agaagtcaat tctgtttcag caaaacgtgc tgaaatcgat aaagcaaaac acgaattaga
    24481 agatgcagaa aataactatg atttagaacg cgctgctgta ttgcgtcatg gtacgatacc
    24541 tcaattagaa aaagaattga aggaattaga agctaaagca aaagacagcg agattaagat
    24601 ggttcaagag tccgttaccg aaaatgagat tgctcaagtc gttggcagat taacgggtat
    24661 ccccgtaacg aaacttgtag aaggtgaacg agaaaaacta attaaattga atgaaacact
    24721 tcataaacga gtgattggtc aagatgaagc agttgatgcg gtcagtgacg cggtaattcg
    24781 ttcacgggct ggattgcaag acccaaatcg tcctctaggt tctttccttt tcctaggacc
    24841 aactggtgtc ggaaaaaccg aattagcgaa agcgttagct gagaacttgt ttgactcaga
    24901 agatcatatg gtacggatcg atatgagtga atatatggaa aaacatgctg tgtctcgtct
    24961 agtcggagct cctccaggct atgtaggtta cgaagaaggt ggtcaattaa cggaagctgt
    25021 cagacgaaat ccttatacaa tcgtcttgtt ggatgaaatc gaaaaagcgc atcccgatgt
    25081 cttcaatatc ttgttacaag tcctagatga cggacgcttg actgattcaa aagggcgagt
    25141 agtagatttc aaaaatacgg ttctgatcat gaccagcaat atcggttcac agttactgct
    25201 ggaaggcgtg actgctgatg gaacgattcc agaagcagtg gctgaacaag tcaacacgct
    25261 attacgtgga aacttcaaac cagaattctt gaaccgaatc gacgacacga ttttatttac
    25321 accattgagc ctagacaacg tgaaaggaat cgttgacaaa atggtggcgc aattggcaca
    25381 acgtctggaa catcaagaaa tcctgctgac aatcagtgat gaagccaaaa cgtggattgc
    25441 tgaaaatgct tatgaaccag catatggtgc aagaccattg aaacgattta tcactaagga
    25501 agtagaaaca ccactagcta aagaaatcgt tgcaggacat gttatgccta aatcaaaagt
    25561 aacgattact ttacttgatg gacaacttca tttcaaaaca gaagagctag aagaaatcgt
    25621 ctaatcttcc attgagacta taaaagaaaa aaggggtctg acacaactag tgtcagacct
    25681 ccttttttca aataaacagt gttccagaag tagtttcttc gaaaaataag ccgaaatttc
    25741 ttgaagctgc ccgcttctgt cacaacctct tttattaggt atttttcact ttttctaatt
    25801 tataactttc aaagtaacgc tcatcttttt tactttgaga ccatgcaaac aatcccatta
    25861 aggcagcacc tatcgtattt gtcagcaagt cgcccatcgt atccatcaat gctgctcgtc
    25921 cgacaaacag tgtgccatca gaagcagcaa aacgttgaag attcatgcct aagaactggt
    25981 cgcataagaa ttcccagaac tcccaaaaca cgccgcaaag tccagcaaac gcaaagccga
    26041 ataagaggaa caaccaagga ctggtttttg atatctcagc atctttcatc aagtaaccaa
    26101 tcaatccata gccaagagct gtcaggacca ttggactcac cgcatgtaag attttgtccc
    26161 aaaaagagat gatactgatc aaatgcatcc ctgtgcctaa aaagacagag atgaacaaga
    26221 aaaaccagta aaacaaaacg attgctgctg gtattttaag tttgaaaact ttcaaaatga
    26281 cttgtggcat gaaaatcaat gcaatcccta ataaagattc cacgataaat gtgattcctt
    26341 gagaagtcga atatttttgt gtgataaatt cataaaaatt atagcagaca acgaatacac
    26401 caaaagcaag taaagctatt tgcacctttt tgatttcttt aatcactgaa agtccctcca
    26461 tctaaaaatc tttttacttc tgaaagcaac tcaatttctg aagaaaccac ttttccgttc
    26521 aatttgatca aacctattgt atataagttc aggtagtgaa attgattttc agctgtttct
    26581 tgtagtgcag cgattttttt cgggtgggtt ccgccttgct gtcgagtatc agtatataag
    26641 ccgatcactg ggatgccttt cgcataagcc acaccgattt ccgatgctac cccggcatcg
    26701 atcgtcagcc catctagtaa agcaatcatt aaatcactag ccaacacttt ttctgtgtca
    26761 gcaagagcaa tcattcgact gtctgcataa gcagttttgt cattgattgc ttcattttct
    26821 tgaggaagat agatcgaaag ctcagaagag agctctctga tttctttaac taactgttgg
    26881 ttatataaca aatcactttt agcaaacatt ggtgcggcaa aataaatttt catctaaaca
    26941 tcatcctttt tatcaaaaat aatcgctaaa gtaagcttcc atgtttggaa tgatacgctc
    27001 tagtgacttc agtgtttctt catctgtttc taaccgttcg attcttgcca aataagaagc
    27061 acggcgataa ttcatcatca agcaagtcaa tgtttggata tccagtcgaa cggattttcc
    27121 tataggttca tttaagacac ggacttgtcc ctgttcatcc catgttaaag cgaagacacc
    27181 attattccaa ggagcgacag gatcttcaat gatgaaatga aaagcatcag ctgttccaac
    27241 aaacggaaac cgttgaagga attcttttac atcaacgatc cgagccataa aatatggttc
    27301 gatctgctct ttgatctgac tatcttcaat caaaaatgct aaaggctcat ttttataaat
    27361 atctccatgt acccagtaga tcatggaaaa atgtgcggaa ataaagttcc ataagccatt
    27421 tcgagcttct tgatcaagat agaacatttc ttttacgtga aatatttctt cagctaccca
    27481 gtagaacaga acacctcttg gttcatggtt gctatcgtag tagacagcgg ctgtgcgctc
    27541 atcttcattt tcgaaacgcc aatactcttc ccaatgaaaa tcactgcgga ataaagcacc
    27601 atggttttgt tgggcaaatt tgtcataaac ggaaaatacg tctggatgat caactggtaa
    27661 tcgctcaacc ataccactta ctgggatttg tttaggtagc tgtgtatctc tgattttaaa
    27721 ggaaagttta tcagacatga tttcccatcc tttacgccga tagtagggga tactgtaagg
    27781 atacaaataa gagatccatt gcttattctt gcgcatatta tccaatgcaa cgataattag
    27841 atcttgcatc aatccatggt tagcatattc tggataagtt ccaactccag tcacaccacc
    27901 cattttataa cgtgcaccgt gaatattgac ttcacaagga tagatagcga tttgagagat
    27961 cagtttattt tcgtggaacc atccgaacac tttcgatact tccaaaatcg gttttttgga
    28021 acggataaaa gctcgtttat tctcaaaccc gctttcctcg atgtctgctt cagtcacttg
    28081 gaacacatag gaaagcaatt cattgaattg atcgatatgt tcttgagtga ccggttttaa
    28141 ttcaagattt tctctaaaat ctttttgatc cattttttca tctccattta ttagcttgat
    28201 aacagtatag caaaattcta caaaaaaaac ttctatagct gactaattaa aaactcttta
    28261 aattactgct tttcgttggt ataatggaaa gtgctgatta tatgaaaaga ggagacgcta
    28321 tggatataaa gaaaatgaaa gaacgccaag agcagattcg taatttttcg atcatcgctc
    28381 atatcgacca tgggaaatct acattggccg atcgtatttt agaaatgacg cacactgtga
    28441 cgtctcgcga aatgcaagat cagctgttag actcgatgga tttggaacgt gaacgtggaa
    28501 tcacgattaa attaaatgct gtagaactca attacacagc gaaaaatgga gaaacatata
    28561 tctttcactt gattgacacc ccagggcacg tcgacttcac ctatgaagtc tctcgaagcc
    28621 ttgctgcctg tgagggtgcc gttttagtgg tcgatgcagc acaaggaatc gaagcacaaa
    28681 cattggccaa tgtttattta gcgttagaca atgatttgga gatcctgcca gtcatcaata
    28741 aaatcgacct acccgcagca gatcccgaac gtgtccgtca agaaatcgaa gacgtaatcg
    28801 gaatcgatgc tagtgaagct gtattagcca gtgccaaatc agggattggg attgaagata
    28861 ttctcgagca gatcgtggaa tatgttcctg caccaagtgg agacttagat gcaccgctaa
    28921 aagctttgat ctttgactct atttatgata gttaccgcgg tgttgttcta aatgtccgga
    28981 tcacggacgg tatggtcaaa cccggagaca aaatcaaact gatgagtaat ggcaaaacat
    29041 ttgatgttac agaggtcggg gtcttctcgc caaaagcagt tgctagagac tttttgatgg
    29101 tcggtgatgt cggttatatc acagcaagta tcaaaactgt ccaagataca cgagtagggg
    29161 atacagtaac gttagcagac aatcctgccg ctgaagcttt accaggttac cgaaaaatga
    29221 atccgatggt ttattgtggt ctttatccaa ttgatacttc tcgttacaac gatttgcggg
    29281 aagctttaga aaaactgcaa ttgaatgatg ctgctttaca attcgaacca gaaacctctc
    29341 aagcattagg ttttgggttc cgctgtggat tcctcggact tcttcatatg gatgtcgtcc
    29401 aagaacgctt ggaacgggaa ttcaatctag aattgatcac gactgcacca tccgttattt
    29461 accatgttaa taaaacggat ggtacgactg ctacagtaga taacccggca gattttcctg
    29521 aacctgtaac gattcaggat gtagaagaac cattcgtcaa agcacagatc atggtcccaa
    29581 atgattttgt cggtgcagta atggaacttt ctcaacgaaa acggggagaa ttcattacga
    29641 tggattattt agatgattac cgagtaaatg tcgtctataa tattccgctt tctgaaattg
    29701 tctttgactt tttcgacaaa ttgaaatcaa gcacgaaagg ctatgcctca ttggattatg
    29761 aaatgtctgg ttatcaaaaa agcaagttag tgaagatgga catcttgctg aatggagaaa
    29821 aagtcgatgc attaagcttt atcgttcacc gagactttgc ctatgaacgt ggaaaagcaa
    29881 tcgttgaaaa actgaaaaaa ctaatcccac gccaacaatt tgaggtgcca atccaagcag
    29941 ctattggaca aaaaatcgtt gcccgttcag acatcaaagc cttgcgtaaa aacgtcttgg
    30001 ctaaatgtta tggtggagat gtttctcgta aacgtaaact cttagagaaa caaaaagaag
    30061 ggaagaagcg gatgaaacaa atcggctccg tcgaagttcc gcaagaagcc ttcatggccg
    30121 ttctgaaaat ggacgaggac gaaccgaaga aatagcaagg gtttgtttga aaacagtgta
    30181 aaaaataaac catgtttaca tggatttgcc accggtttgc caccggtggt ttttttcggt
    30241 ggcaaaaatc aagaattctt tctaagattt tccatgatat cgaccgtttc atttctcatc
    30301 ttatctgtta catgcgagta agtatccatc gtaattgaaa ttctgctgtg gcccaatcgt
    30361 tcagagattt ctttcatttt tgcgccattt tcgagaagaa gtgtagcatg agtatgtctg
    30421 agagaatgga agttaaaaga gagggagagt gcattcgata tcctcctagt attccatttc
    30481 actacacttg gcgtaactag ctcaccgtct tccttcgtac atactgcatt tgaatcaatg
    30541 tagagctttc catacttcat tcgattttct aattgttgtt tcttatgttt tttcagaatt
    30601 gctagcaagg tttgtccaat aaaaatcgtt cgattggaac tgcttgtctt tggcgtacca
    30661 tatacccatg cgccgtcatt ctttaccatt tgtttctcta cagtaattgt tccatttgaa
    30721 aaatcgacat catcccacgt cagaccacaa acttcgccaa cgcgcattcc cgtataaaat
    30781 ccaatattca aaggaatata gaaaggatgt ccttcaggag taatttctag catatgatca
    30841 aagtcctcaa gagaaatgat ttttagatct tttttagtcg ttggtcgtgc ttcatatttt
    30901 ggtattttta catacagcat aggattttgc ttgattaatc cccaaggata aaccgccata
    30961 ttcagcgcat tcttaaggac agagtgagta atagtcattg ttttcttcga gtaacccttt
    31021 ttaaattcag cattgatgaa attttgtaaa agagcagggg agagatccgt aagttttttc
    31081 tttcctaaat aaccgtttat atgatttttg atggtaaatc ggtagttttc ataggtattg
    31141 tattttagat ttagtttaac gtattcctcc atccaaaaat caaggtattg ttttactcga
    31201 gtatccgtac ctaaaaagta ttgtcctgtt tcgtcaatat ctgataaaac ttttcgtaaa
    31261 gcagcttcgg cctctggtcg ggtgtctccg ccaactttct ccactttttt tcttgagcca
    31321 tcatcattga tatct
//
LOCUS       DBGZHO010000026        29948 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.026, whole genome shotgun sequence.
ACCESSION   DBGZHO010000026 DBGZHO010000000
VERSION     DBGZHO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.026"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            18..395
                     /locus_tag="ACN3HL_001416"
     CDS             18..395
                     /locus_tag="ACN3HL_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006304.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            1001..1615
                     /locus_tag="ACN3HL_001417"
     CDS             1001..1615
                     /locus_tag="ACN3HL_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8006305.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            2388..4127
                     /gene="yfcC"
                     /locus_tag="ACN3HL_001418"
     CDS             2388..4127
                     /gene="yfcC"
                     /locus_tag="ACN3HL_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HHC8006306.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            4284..5468
                     /gene="iadA"
                     /locus_tag="ACN3HL_001419"
     CDS             4284..5468
                     /gene="iadA"
                     /locus_tag="ACN3HL_001419"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HHC8006307.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            5579..5782
                     /locus_tag="ACN3HL_001420"
     CDS             5579..5782
                     /locus_tag="ACN3HL_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HHC8006308.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(5883..6545)
                     /locus_tag="ACN3HL_001421"
     CDS             complement(5883..6545)
                     /locus_tag="ACN3HL_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006309.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(6558..8060)
                     /locus_tag="ACN3HL_001422"
     CDS             complement(6558..8060)
                     /locus_tag="ACN3HL_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006310.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8608..10287
                     /locus_tag="ACN3HL_001423"
     CDS             8608..10287
                     /locus_tag="ACN3HL_001423"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HHC8006311.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            10414..10893
                     /locus_tag="ACN3HL_001424"
     CDS             10414..10893
                     /locus_tag="ACN3HL_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HHC8006312.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            11112..11792
                     /locus_tag="ACN3HL_001425"
     CDS             11112..11792
                     /locus_tag="ACN3HL_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HHC8006313.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            11800..13131
                     /locus_tag="ACN3HL_001426"
     CDS             11800..13131
                     /locus_tag="ACN3HL_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HHC8006314.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            13146..14108
                     /locus_tag="ACN3HL_001427"
     CDS             13146..14108
                     /locus_tag="ACN3HL_001427"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HHC8006315.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            14219..14557
                     /locus_tag="ACN3HL_001428"
     CDS             14219..14557
                     /locus_tag="ACN3HL_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HHC8006316.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            14636..15343
                     /locus_tag="ACN3HL_001429"
     CDS             14636..15343
                     /locus_tag="ACN3HL_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HHC8006317.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15446..16927)
                     /locus_tag="ACN3HL_001430"
     CDS             complement(15446..16927)
                     /locus_tag="ACN3HL_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006318.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            17236..17772
                     /locus_tag="ACN3HL_001431"
     CDS             17236..17772
                     /locus_tag="ACN3HL_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8006319.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            17850..19220
                     /locus_tag="ACN3HL_001432"
     CDS             17850..19220
                     /locus_tag="ACN3HL_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HHC8006320.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            19287..19622
                     /locus_tag="ACN3HL_001433"
     CDS             19287..19622
                     /locus_tag="ACN3HL_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006321.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(19703..20560)
                     /locus_tag="ACN3HL_001434"
     CDS             complement(19703..20560)
                     /locus_tag="ACN3HL_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006322.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            20667..21182
                     /gene="tadA"
                     /locus_tag="ACN3HL_001435"
     CDS             20667..21182
                     /gene="tadA"
                     /locus_tag="ACN3HL_001435"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HHC8006323.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            21205..21289
                     /gene="ffs"
                     /locus_tag="ACN3HL_001436"
     ncRNA           21205..21289
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACN3HL_001436"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            21499..22884
                     /locus_tag="ACN3HL_001437"
     CDS             21499..22884
                     /locus_tag="ACN3HL_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HHC8006324.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            22921..23598
                     /locus_tag="ACN3HL_001438"
     CDS             22921..23598
                     /locus_tag="ACN3HL_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HHC8006325.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            23606..24370
                     /locus_tag="ACN3HL_001439"
     CDS             23606..24370
                     /locus_tag="ACN3HL_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HHC8006326.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            24372..25031
                     /locus_tag="ACN3HL_001440"
     CDS             24372..25031
                     /locus_tag="ACN3HL_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HHC8006327.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(25061..25570)
                     /locus_tag="ACN3HL_001441"
     CDS             complement(25061..25570)
                     /locus_tag="ACN3HL_001441"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HHC8006328.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(25682..26680)
                     /locus_tag="ACN3HL_001442"
     CDS             complement(25682..26680)
                     /locus_tag="ACN3HL_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHC8006329.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            26881..27465
                     /locus_tag="ACN3HL_001443"
     CDS             26881..27465
                     /locus_tag="ACN3HL_001443"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8006330.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(27542..28717)
                     /locus_tag="ACN3HL_001444"
     CDS             complement(27542..28717)
                     /locus_tag="ACN3HL_001444"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HHC8006331.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            28799..29179
                     /locus_tag="ACN3HL_001445"
     CDS             28799..29179
                     /locus_tag="ACN3HL_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HHC8006332.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            29253..29615
                     /locus_tag="ACN3HL_001446"
     CDS             29253..29615
                     /locus_tag="ACN3HL_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006333.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         9744 a         5010 c         6206 g         8988 t
ORIGIN      
        1 aaaggtgtgt gttcactatg ggaaaattag tcgctgttgc acagtcgctg cttgatatac
       61 tcaagtggct gatggaagga agcaattgga tatttgtgtt gccactattg cttattagtc
      121 tatttatcat gtttcgcatg gtcagaaaaa aagaaacgtt tctgattttt atctggtatg
      181 cagcatccgt tggggttgct accttgatgg ttgaattggc gttaggtagt tgggaagctt
      241 gcgtatttgc tttatttttt gctgtactgt atctaatcat ttatatccca tatatgaaaa
      301 gaaagtctcg gataggcaga aaaggtagac atacaactac tttttctagt acagattctc
      361 tcgaacaaag tagaagaacg agaagaagac ggtaatattt agtaggtata cgcaaaaaaa
      421 gataaaataa tggataaact attgagatga gagatttatt taattggtgg aaaaaagctt
      481 ttttcactta tataaaagaa tcttttttaa aggaatgctt gttgtatcgg gataagccat
      541 tccttttttt atgttattta tatatatata aatcatacca atgttttttt gtattttctt
      601 gcttgcactt ggataagaga ttacttacaa taaattcaga tagaaacagc tgaataaaaa
      661 aaggctccct gacccttagt tggcgctaag aatcagggaa tgaccagtca cacacataca
      721 ccctgaccga tcattttgcc atagtcaatg cagtgcatcg acctaattta ttgtacctaa
      781 tctagggtga aaattctacc cctatgtaga tattttccat ggtctgcacg ttgttttatt
      841 tgctatgtca aggtattggg cgtattcgtt caatgccttt tttgtgtttg aaacagcaaa
      901 gaccacatgt gttactgtct aactactgtt tttttatgta cttccttaga ttaggcagct
      961 gtttctattc atgtcaagta tagctaggcg ggagagataa atgagtttat gttattttga
     1021 ctattatcac caattggaag agaaattaag gatagaagag ccgctgatgc ttcaagctgg
     1081 cacttggatc gcgaaacaaa ttaatcaagg tggtagattg cagatatatg ctagccgcac
     1141 actaagtggt gtagcatttg aattttggga tcaaaccccg gatcttgtac caagtatatt
     1201 gattgaaaat ccagccggag gtgtctatga aacgctagaa ggtgcaggac aggcaattat
     1261 tgatcagctt tctgtcaaat cagaagacat ttttcttctt ctttcgaatg aaggaagaaa
     1321 cccggcaatc atcgaactag ctcagtggat caaagaaaat ggtcatccat taatcattgt
     1381 tactggattt gatttgtcac gaagtatcaa atcgcaacat agcagtggtt tgcgattatt
     1441 tgaatttgct gatttggttt tggacaacca cgccaattta catgatgcag tcttgacttt
     1501 gccaaatcta gatccagcga tctgcggaac agcctctctt gcaacgatct ttttgctgca
     1561 gcaagttttg tattttacag caaaacagct agtccaggac acaagtggaa aatagttatc
     1621 cacatgttga caaagttcct taaaaaaata atgttccaca taaaaatgga gcgtttgaaa
     1681 aaaagaaaac gattattaat gaggattaac aacgactact ttttttgttt tagttatttt
     1741 aagatggatc atctttgatt ttaagcttgt tttgtttaaa gtttgttatt tttataagtt
     1801 gtttcacagt tatgagaaat gagttataag aatatgtagt gtcagaaaaa taaaaagtag
     1861 tggaaaaaga gacaagaaag aatccatatg gattctttct tgtctcttaa tacacgttga
     1921 tgaaagagtc ttccccaaaa ctctttacaa agtaattata gtacatttgt tatcattatt
     1981 gcaatgaagt ttacctgata taacaaaatt gtccaacagg ataccttttt ctaatagaaa
     2041 taaaatacac aaaaattgaa ggatagataa tggatattta taagtgttta ttattttttt
     2101 tgcaatgaaa ttcaattttt caatgattgt aaaatgaaaa aaacaggacg agattttctc
     2161 taatctaaaa ataaaaaaag aattttaagg aaaaacagag aaataaaata cttaatataa
     2221 atggaaagag aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat
     2281 tttctaataa attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc
     2341 attttttatt catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa
     2401 attcttcagg aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca
     2461 ttatttttgg tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt
     2521 tcagcacgca agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt
     2581 tacgtcaaga ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat
     2641 tagaagaact gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat
     2701 tggaaaaagt cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct
     2761 ccttgacaga tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa
     2821 aattgcataa aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa
     2881 attttgtttt tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg
     2941 cattgatcct tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg
     3001 caggtatcta tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat
     3061 tattctttgc tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat
     3121 tctcaatggt gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa
     3181 ccgtgactta tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg
     3241 tagcggtggc tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga
     3301 ttatgtgggt agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa
     3361 tccgtaaaaa accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata
     3421 tcaaaaagac atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag
     3481 agatgttagt tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc
     3541 cagaaatcgc ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt
     3601 tcaaattaga tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg
     3661 atttagctgg tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag
     3721 gatctgatgc atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt
     3781 tgaccggtgt tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca
     3841 acttggttgt tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac
     3901 tggcagattt agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag
     3961 gttttatgga cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac
     4021 ggatcgaatg ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt
     4081 taggaactat tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg
     4141 taaataaaaa agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa
     4201 aatcaaagga gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat
     4261 acttaaagaa agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag
     4321 attacttagg aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac
     4381 agctagaagg cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac
     4441 taaccccggg tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt
     4501 atcaaaatcg aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag
     4561 ttgtcggttg tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag
     4621 cgaaaggtct ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc
     4681 cggtaaaaac agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg
     4741 gaatcggaga aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg
     4801 ctcgtgcagt agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca
     4861 atgtccactt aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa
     4921 cagaaattcc gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg
     4981 aagcttgcgt ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc
     5041 ctgatttttg ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga
     5101 tcgaggaaga tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc
     5161 cttattttga tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc
     5221 tagtagggat caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag
     5281 ctataaccag taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg
     5341 gtgctgatgc agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg
     5401 ctaaaggaga aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa
     5461 gtttttaatc aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat
     5521 ctgttgttga tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat
     5581 ggcagattta aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga
     5641 agcatacggc aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact
     5701 aggtgctgac atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc
     5761 tcgaaaagac gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa
     5821 tccgaaccat atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt
     5881 ttttaaactt cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt
     5941 tttgctactt caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt
     6001 tcttggaaaa gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca
     6061 tccgctacga ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc
     6121 tgacctcccg aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga
     6181 gccagtcgat ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt
     6241 gctgctatga cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata
     6301 atcgagacat catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga
     6361 tagtatacct ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt
     6421 tttccagaac cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct
     6481 acatctttat aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt
     6541 aacatcaaat tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct
     6601 atagaagcta aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc
     6661 aattgtgcag gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga
     6721 ttattcgtgg ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc
     6781 atttgtccac cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt
     6841 agctgctgtc ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca
     6901 agaatcatac aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct
     6961 cctaaagata gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc
     7021 agagtaagta tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt
     7081 gccacgttgt ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta
     7141 aatgtatctg tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga
     7201 tcagatagag tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca
     7261 tttgcaaaag tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata
     7321 cccatactgc cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg
     7381 gtatcttcat cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt
     7441 tctgctagag tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct
     7501 tcaccatccg tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac
     7561 acaccactga tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca
     7621 ggttcaccgc ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg
     7681 gcagttattc catcttttgc catagctgag gcggaacttt caaaggaata actctttaca
     7741 ttatctaatt cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg
     7801 cctggatctg gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta
     7861 aatgaagctt ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga
     7921 ttcgctgctt cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg
     7981 gctgtgaaca cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat
     8041 gcacgtttca taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca
     8101 acctatctta aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg
     8161 tatatataaa aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt
     8221 tcaaaccgac gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag
     8281 ggatttttac gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt
     8341 tgtataataa tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca
     8401 aaagatccat tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac
     8461 gcggatgtgc tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca
     8521 tatgcttcat tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact
     8581 tggatgtcat aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc
     8641 gttcgtgaaa atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta
     8701 gattgtgggc taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat
     8761 tttacgtatt tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat
     8821 gcagatgcga tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg
     8881 acagagttga cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga
     8941 tttaaggatt tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg
     9001 agctttttcc gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa
     9061 gaaggtagta tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat
     9121 caaacagatt atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt
     9181 gaatcggcaa atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa
     9241 gtatttgata cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat
     9301 ttgcaacgag tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg
     9361 actggtcaag atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta
     9421 ccaagtgaag atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg
     9481 atcattttag aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac
     9541 ggtacacacc gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca
     9601 agcatcgcga tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga
     9661 acagtgaagt tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg
     9721 caattaatga tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt
     9781 gaattagctg ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat
     9841 attactggac gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact
     9901 acaagtgcag aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt
     9961 ttacgtgatc gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt
    10021 cggcgagaaa agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta
    10081 aaagctagcc gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa
    10141 catttagaaa gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta
    10201 ggccgttact tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa
    10261 gctactcaac gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt
    10321 gctcgtcttg ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt
    10381 tataataaac gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt
    10441 tatttagaag aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa
    10501 tctttcacag aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc
    10561 gtagtgaaag gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta
    10621 gattacaaaa aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat
    10681 tttgtattaa tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc
    10741 gcacatcctg attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt
    10801 gtgtcaagcg gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc
    10861 gtccatccta tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc
    10921 agagacctca aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt
    10981 acaattgctt tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt
    11041 ttttcattga tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg
    11101 aggtgtaaaa tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa
    11161 atggccaacg cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg
    11221 cagaagaagt aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag
    11281 atatgattcc tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg
    11341 attatgcgaa cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt
    11401 ttccattcgg cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg
    11461 gtatcgttca gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga
    11521 tttatcatgc aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg
    11581 atattgatgt cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag
    11641 caaaggctgc gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc
    11701 ctgtcattga acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa
    11761 taatgagcgt ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg
    11821 attttagaat atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca
    11881 aaagaattga atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc
    11941 ggactagttt caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa
    12001 catattgaac gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc
    12061 ggggcggcag gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat
    12121 gccatggaac gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc
    12181 caaaaattag cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact
    12241 gctgagattg caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat
    12301 acatttacag tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat
    12361 atcatgcttg tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca
    12421 gatacgattt ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc
    12481 gtcaaccgcc atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg
    12541 ccaaaccaga tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg
    12601 agtattgcct ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt
    12661 tccgatgact tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag
    12721 cttgtccagc gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc
    12781 catacgattg atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta
    12841 gtagcaccac aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc
    12901 atttctgatg tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa
    12961 caagtgaacc tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca
    13021 cgtgtattgg aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac
    13081 accatcgttt ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga
    13141 gtgaaatgac agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta
    13201 tccacaggca tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac
    13261 tattacggga aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc
    13321 ttcgcttttt agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca
    13381 tcgtgactga tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa
    13441 aactgatcaa aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa
    13501 atacaaaagc aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat
    13561 ctttaaagat gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag
    13621 ggcgcttttt gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa
    13681 attatccatt tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg
    13741 ctaaactttc cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa
    13801 taatccttcc gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga
    13861 tcgtttcact tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc
    13921 cttcagggta ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta
    13981 aacgccatca tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag
    14041 aagtagagga aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa
    14101 cagaatgata cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt
    14161 caagatcttc tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat
    14221 gacattacca aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt
    14281 gatttgccca gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga
    14341 cggattagtg gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt
    14401 gattaaagac ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa
    14461 gaacatccgt ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc
    14521 gatgaaactg aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca
    14581 ttcttttcct actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta
    14641 tggttatgga atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt
    14701 tatttccgga attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag
    14761 aagcaaaaac aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat
    14821 aaataatgtc ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa
    14881 taagatgttg agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt
    14941 agcagctcat gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat
    15001 tcgtgcagca cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat
    15061 ggtaggtgta ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc
    15121 tttagcatta cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc
    15181 aatccaaatt ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca
    15241 cgtattattt gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct
    15301 gttgcgcttg atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa
    15361 atcagcgctt tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga
    15421 ataagaggat gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt
    15481 tcatatacag ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg
    15541 tatccagata gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca
    15601 aatcagcatg ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca
    15661 aatggctttg aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta
    15721 actgctcttt cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga
    15781 tttggtttct ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt
    15841 cctgtataaa agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac
    15901 tactgctgga ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat
    15961 aaattggtat tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca
    16021 attgaccgac ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct
    16081 gtttttgtcg aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg
    16141 ctctctctgt ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg
    16201 aataatcatg tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg
    16261 gaaaatatgc ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt
    16321 tttcttgttt tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta
    16381 attcaagtga ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa
    16441 gatagagacg gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga
    16501 tccgtaaatg gaattttttt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg
    16561 agggcgatat ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat
    16621 tgattagtaa catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact
    16681 tagaaaaaac agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat
    16741 gattagaata aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc
    16801 ggatcagttc tttgattgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag
    16861 aacaattatt tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa
    16921 ttagcataaa tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt
    16981 ggaaagtcat ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt
    17041 tatttaattt ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa
    17101 gatattcttg tttttaaggc ggaaaaattg atttttaatg gatataacta aatatgtttt
    17161 gataattatc aataatattt ttagaattat ttatgttatt tatttatggg tagatgaaaa
    17221 gagacggagg taagaatgat ggggagagta acaaattata gtaaagaata tttgctgttc
    17281 aaaagtatgg tatacgtgga agaatatgga atgaagtcaa ttactgcaag agagttagca
    17341 gagttctgcg gttgttctac atacccgatt tatacacatt tcaaatcaat cagcgggtta
    17401 aaagagaaga tattagaaga aatcactgtt tattttgaaa actacttagc tgaatgcagt
    17461 tccgatgatg ttttaagcat tgtctactta ttgaaagatt ttttttctat ccatgaaagt
    17521 attcgtgaaa tcattgcaaa atctgattta gacatggatt cgctatttaa gcggccattt
    17581 ttctcatatg tcaaaggtca cacgaagatc aaagaagaaa agtcgcttga attggtatgg
    17641 cttaatgcat tgggaagttt gcgctcagat gattcttctc aagattttct tgaaatgatg
    17701 aacgctgttt gggataaaaa cgaggtgacg gatgaatact tggaaaatat cttaaaggaa
    17761 cagtcacctt aggcagcaac atgaaaaagt agatcagcca cctttatttt tcgtaaaaaa
    17821 gattgtaaaa tgtctaacga aacattggaa tgaaggagga agcgacaacg ttaccacagc
    17881 aatttatcaa aaaatatcgt cttcttttag gcgaagaagc atccgatttt ttttctgcgc
    17941 ttgaacaagg aagcgtgaaa aaaggatttc ggtggaatcc actaaaaccg gcaggattgg
    18001 acatggtcca aacttaccat agcgaagaat tacaacccgc tccctacagc aatgagggat
    18061 ttcttggcac tgtcaatgga aagtctttcc tccatcaagc tgggtatgaa tatagccaag
    18121 aaccaagtgc aatgatcgtt ggaacagctg ctgcagcaaa acccggtgaa aaagttttgg
    18181 atttgtgtgc ggctcccggt ggtaaatcaa cccaattagc tgctcaaatg aaggggaaag
    18241 ggttattagt gacgaatgag atctttccga aacgtgcgaa gattttatca gaaaatatag
    18301 aacgatgggg agtttcgaac gcaatagtga caaatcatgc acccgcagaa cttgtccctc
    18361 atttttcggg cttttttgat cggatcgtgg ttgatgctcc ttgttcagga gaaggaatgt
    18421 tccgaaaaga tccaaatgca ataaaagagt ggacagaaga atctccgcta tactgtcaaa
    18481 aacgtcagca agagattttg tcttcagcaa taaaaatgct aaaaaataaa ggacaactga
    18541 tttattcgac ttgtacgttt gcaccagaag aaaatgaaga gatcattagc tggcttgtag
    18601 aaaattatcc agtaacgatt gaggagattc ctttgactca atccgttagt tcaggacgtt
    18661 ctgaatgggg aagcgtagct ggtttggaaa aaacaatacg tatatggcct cataaagatc
    18721 agggtgaagg acattttgtt gcaaagctga cttttcatgg acaaaatcag atgcataaag
    18781 aaaagaagac acgaaaaaaa agtaaagtgc aaatgacaaa agagcaggaa aaactctgga
    18841 cggagttttc aaatgatttt cattatgaag ctactggaag acttttagtg ttcaacgacc
    18901 atctttggga agttcctgag ttagcccctt ctctcgatgg tttaaaagtc gtacgtacag
    18961 gtttgcattt aggagatttc aaaaagaatc gatttgaacc tagctatgca ttagcgcttg
    19021 ctacaaaaaa gatagagaat ataccttgct tgccgatcac tcaaaaggaa tggcaatctt
    19081 acacagcagg agaaacattt caacgtgatg ggaatcaagg atgggttttg ctagtattag
    19141 ataagatacc tgtcggattt gggaaacaag taaaaggaac agtaaagaac tttttcccta
    19201 aaggattgag atttcactga gtggattagt tcgtttattt ttttgtctat gctatgatgg
    19261 agatagataa aaaggagctg atacttatga aaacatcaac aaaagtaaca atcggattaa
    19321 gcgtagcagc cgctgccagt gtagcgacag cagtcgttgt atcgggaaaa gtaatggaaa
    19381 agatccatca tatgactact cggacgaaag taaaaaaatt cgtctatgac aaatttgatg
    19441 gaaatgaaaa attactagaa atcgtagatg gtctttcaga tagtgacttg gattctttga
    19501 tgggaatgtt agcaaaaatc aaatcaggaa aaaagaaaat ctctgtttat ggtgattcaa
    19561 tcaaagattc aaccgaagat gtaaaagacc ggctaatgca ttttgttgaa aaaatgatgt
    19621 aagagaaact agcttttgaa cactattcat tcgaaataag gggttgtgac aaaattattg
    19681 tcacaacccc tttaatctat ctttaattat gttcatgaag caataaaaga tagcaaaaca
    19741 gtaaatcgtt ggcttttttt agattgaaac cagactgttc ttgaaatttt tcgattcgat
    19801 attttagagt attacgatga agaaacagtg tttttgcagc agagctgaca ttgcctaatt
    19861 cattccataa ttcttgaatg atcacttcca tttcattttg tttgatcagt tctatgtaac
    19921 ttttgatcaa cttactatct tttacagtat cttttgtata gtaatgtaaa gccacatctt
    19981 gcatagaaaa agtacggctg tgagtataaa gattgttttg ctctgttaaa aaaatttttc
    20041 tttcttcagc aaacaaaggg acgaggtcgg tgccaggtga atggaaagaa ccaacgaata
    20101 cagacgttgt cgtatcaaaa tcagcatcta aagatagaaa aataccgttg atttcagtag
    20161 catcaagata atcacggttt atttgttcga ctaagagcgc atctgtgtct gtataaaaaa
    20221 agaaatcagc agaatagcga aataattcca aaatagtatc ttgccattct ttttttaaga
    20281 attctccttt tgattcgacg tgaagctgga tcaaacgaaa gcttttttct tgaacacaag
    20341 aagcatcttt aaaaagatag tgataccatg ggtgtttttt ttgatcgttg attacaggga
    20401 ataacgcttt caaaaggctg gtttcttgtt gagataatga atcttgtttg atccagataa
    20461 aagcatcatc aattgcaaaa gaaaggatat ccgcttctga tgctggagag ttttttttct
    20521 gtgcttgtgg gtaaagagca agtaatttat ccattttcat cttgttcacc tcttgtattt
    20581 attttaccat agaaaaaaaa gttagttaca gcctttttat catatgctaa agtaaaacaa
    20641 gaaaaaacaa aggcagggaa gggtaattgg taaatacaaa tcttgatgca gtagaaaaag
    20701 aaaaatggat gcgccttgca ttggcagaag caaagaaagc agaaatgctt catgaagttc
    20761 cgattggagc agtggttgta ttggatggaa aagtgattgg aagaggatat aaccttagag
    20821 aaaccacgca agatgctact acacatgcag aaatgcttgc aatcaaggaa gcctgtgaaa
    20881 aagtgggaag ctggcgcttg gaagatgctg cactttttgt taccttagag ccttgtccta
    20941 tgtgcagcgg cgcgatgatt ttgtctcgtg tagcagaagt ttatttcggc gcgtatgatc
    21001 caaaaggcgg aacagccggt accttgatga atcttttgga ggacgagcgg tttaaccacc
    21061 aagcatatgt agaaggtggc attttagaag acgaatgtgg gatgattttg actgactttt
    21121 tccgaaagct ccgccagcga aaaaagaaat taaaaaaaga ctggtcaacg aatgaaaaat
    21181 aaggtatact attctttgcc gaaaggctag gacaatggtg ggcttgtgaa gcgtgtcagg
    21241 tctggaagga agcagcacta agcaggttcc gccatgtgtc tgattataat gaaacgacaa
    21301 cagactttcg ggtctgtttt ttttattttt atagtactgt aaaaatgaat gttcctgatt
    21361 ttttagccag actgatttat cgaatattgt acttatacaa tttgcttcaa ggcaggaaaa
    21421 actctgaaat agagcttgtt tcaatggaag aaaaagctgc ctatggtatg ataaagataa
    21481 agagaggcga gagggtacat ggaaaaaata gtgattttac atacgaatga tctgcattct
    21541 catttagaaa attggccaag gatcagaagg tttttggatc aacgtaaacg agaaaacgaa
    21601 aagaaagaaa aaacgacaac gattgcagta gatctaggtg attttgtgga tcgttggcat
    21661 ccattgtcag aagcaacgaa tggacaggaa aatatcttgc tgatgaatga agttggttat
    21721 gatgcagcga cgataggaaa caatgaaggc gtaggaaatt ccaaagaaga gttgaatcat
    21781 ttatacgatc atgctgagtt tgatatcatc ctggataact tattcgataa aaatacgctc
    21841 cagccaccgg catggacgaa accatataaa atcattacaa cgaaacacca gacgaaaatc
    21901 ggactaattg catttactgc tccatttccg cttacttata atccgaatgg ctgggacata
    21961 cggaatcctt atgatatttt gccagaatta gtcgaagatt tacgttcaca agtggatgtt
    22021 ttagttttga tgagtcatct cgggattcag gatgatttcc aaattgcaaa agaaatacca
    22081 gcaattgatg ttattttagg atcgcacacc catcatttat tcagagaagg tcacgtaatc
    22141 aatgatgtcc aaatagcagc cgctggaaag tacgggcagt atgtcggtga agtccattta
    22201 accatcgatg aagagaaaaa aatccttaag cattcagcca aagccatccc taccgaaaca
    22261 atgacagctt ttacagaaga tgaacaagaa ataaatagtt atctagaacg tgggcatgaa
    22321 ttattaaaag aaaaagaagt agcagatttg ccattttctc tgagtctaga tatcttcaat
    22381 gagcattcgt ttatccaagt agcctttgag gcggtgaaag aacgaggaaa gacggaagca
    22441 gcaatattaa acagtggtct gtttttaact gaaattccaa aagggcgggt caatcaggat
    22501 cagcttcaca ctgcgttgcc gcatccgatg cacttgttaa atgtcacatt gggtggaaat
    22561 gatctgatcc gcttagtttt agaaatagaa aaaaatcgta actttttacg taactatcct
    22621 atgaagggaa tgggatttcg cggtaagatt tttgggcaga tggtctataa tggaatcaca
    22681 tatgattcta ttaaccatca agtcttttgg aagaacaagc caatcgatct gaataaaaat
    22741 tatactttta ctaccgtaga tcatttgatg tttgttccat tttttccaac gattgagatt
    22801 gctggaaaaa atgaattttt gttccctgaa tttatccgaa gtgtggtagg agattacttg
    22861 aaagctcact acccaatcaa ataaaaacaa ggtataataa aaaagatagg tggtgaacgc
    22921 atgtctgcaa aacaaaatga acagcagaac gttgagcata aaacagaaat tgctaagaaa
    22981 aaatcatcag ctgaacagga aacaacagtc accgaagaac tgacagctgc tttggaagaa
    23041 atcgttgagg agcctaaagc agaaaaagtc aaaggcgagc tagtgacact gttagatgac
    23101 agtaattttt tgataggtga aagacattat cggcttgtgt ccgattatcg tgaaggattt
    23161 aatgcagaaa agcttggaga acgttacagt gatgtactag cccgatatga ttatatcgta
    23221 ggagattggg gttatgaaca actacgccta aaaggatttt tccaagcgga taatcgacgg
    23281 gcgcatccag atcagcgaat cgattccttg gaagactatc tttacgaata ttgcaatttt
    23341 ggttgtgcgt attttgtcat cgagagaatc ggcggtaaaa aagaaaagac aactcagcgc
    23401 cgaaaaaaga aaaaaaacca taatcgtgcg tatatcgatg agaaaaaagg accagtcgca
    23461 tctaatcgca aaaaaccggt tattaaaaat cgaaaaacag agtcagcaaa aacctctgaa
    23521 aaagtaaaaa aacaagaaca acctaaacaa gtagaaaaaa caaaaacagc atttacgatc
    23581 agaaaaaggg aagagtagtg gatgaatgga ctataaagga tatttaattg atttagacgg
    23641 aacgatttat cgtgggacac aacccatacc ggccggtaaa cgatttgtgg aagaattgca
    23701 aaaaagaaaa ttacctttct tgtttgttac caataacacg actaagtcac cagaaacagt
    23761 agctaatcgt ctagcagatg agtttgacat tcatgtagct ccagagacag tctacacagc
    23821 tactttggca acaatcgatt ttatgaaagc agatggaaaa gggaaaaaag tctatgttat
    23881 cggagaagca ggattgattg acttgatttt agctgccgga tttacatggg aagaagaggc
    23941 tcctgactat gtagtggtag gcttagataa ttatctgacc tatgaaaaag tagttaaagc
    24001 aacacttgct attcaaaaag gtgctacttt cattggaacg aacccagata agaatatacc
    24061 tactgaacgc ggccttcttc ctggagcagg gtcagtcatc tcttttgtag agacagcaac
    24121 ccaaacgccg ccgatctaca tcggaaaacc agaagccatc attatggata aagccgttga
    24181 agtattaggg ctgcaaaaag aagaagtaat catggttgga gataactatg aaacagatat
    24241 ccaagctggg atacgcaata atatagatac tttgctcgtt ttatcaggtt ttacaaaaga
    24301 agaagatgta cctgggttgc ctatcccagc tacctatgtg aaacaatcac tggatgaatg
    24361 gagcttctaa tatgaaaaat tcgagatggc agtggatgga atatgctgga ttgttcagcc
    24421 tatttctgac actgatcagt ctggcagttg gtgtgacgat caactttcga ccactatacg
    24481 tatttgatat cggacatttg caaattttgg attatacttc tttagatcaa gagacgttac
    24541 tgaaaaattt tgatcaccta atgaattatc tcaataatcc cttcaaaacc atcctcagct
    24601 tgccagattt cccagtttct gctagcggag cccatcactt ttatgaagtg aaaattttgt
    24661 ttttagtgga ttatgctgtg tttttcatca ctttgatccc gagtattttg tttatcaaat
    24721 atttgcaaaa gaatgatcgg ctttggcggt tgattcgtcc gtttcaaatc ggcatgttac
    24781 tgccagttgt tttcggtttt ttcatgatga taggatttga tcgctttttt atcctttttc
    24841 atgaaacgtt tttcaacaac gatgactggt tattcgatcc cgttactgat ccaatcatca
    24901 atgtacttcc agaagaattt ttcatgcata gctttatctt attttttgta ttattagaat
    24961 tattttttgc tgtttttctt ttcttaggaa aaaatagctt gaaacaaaca aaaaagaaag
    25021 aactcgtcta aatagacgtt ttctttcttt ttttgttgaa ttattgagta aggcgacttc
    25081 ttttttctgg ttctttgtgt gctaatcgac tggcagcagc agcggcgatc gctccgacga
    25141 tatcatctaa gaaggtatgg acatgaacgc catcgtggct gtttagttct tttaaaatac
    25201 caggtttcac cttgtcgata taaccataat tcgtaaagcc gatcgtaccg taaacattca
    25261 cgattgacaa ggctaggatc tcatcgatac cgtaaaggcc ttcgtcatct tcgataatat
    25321 gttgcaacgg actcatcaat tttttctttt ctgctaatat atctaattgg attccagtga
    25381 taatggcgtt atgtacttca cgctttgtta gcacgctgtt gacactttca gtacaatccg
    25441 ccaaagtcaa atcagaaata tagtcttttt gtaaaaacat gacaagttgt gcgatatctt
    25501 ctacagttac gccacgttcc ttcaatagtt ctcttgcctt ttcttctaaa gtctcagttt
    25561 tgacgaccat attattgctc cccctttatt ttttctttct ctatttcatg ttaacggaac
    25621 atgaaaaaaa tgcaagaaac tgctttcggg tttaacttga aatgcaaaga gatataaaaa
    25681 atcaactagg acgaagattt ttatcgtata agcttgtgct gtgaccaggc tgagttcgtt
    25741 cctttggatt aatatagtgt aaagcgttgt tcactgcagt aggtgcttca ccgagcccag
    25801 tagcaatcag tttcactttt ccttcatagg tacagatgtc accagctgca taaacgcctg
    25861 gaatagaagt agacatatct gattttacag taatggcatt tctggtacta tcaagtcccc
    25921 aagaagaaag atgttctaaa ttagaagaga atccataatt gacgatcaga gaatcaatca
    25981 tcaaatcaat cgtctcgtca cttttcactt tttttaaccg gatatctgtc agttccccat
    26041 tattgcctga taatccatcg atgagatagg gagtaagcaa gttgacagat gaagatttca
    26101 agcgtgatac actatgttcg tgcgcacgaa attccgggcg acgatgaatc aagtaaactt
    26161 cgcttgcaat aggctctaac atcaacgtcc aatcgatagc agaatcacca cctccagcaa
    26221 tagcgacttt ttttccagca tacttcatca aatcattcac gaaataatcc aatccgtggt
    26281 tttcaaatga ttcagcatta tctaaattca attttcttgg ctggaatgaa ccatttccta
    26341 aagctaaaat gactgctttg gaataatgga tgcctttatt tgtagtaatc tcgataactt
    26401 cgtcttcacg agtaagcgag agaacttctt cttttaaatg gaatgtatgg ttaaaagtag
    26461 ttaattgttt ttctaattga tcgattaatt cacttgcttt tattgctgga tacccaggaa
    26521 tatcgtaaat atatttttcg ggatacaaag ttgctaattg accaccaagt tgaggtagac
    26581 tgtcaatgat ttttgtttta gcttggcgca ttcctgcgta aaaagcggca aacatcccta
    26641 caggacctgc accgatgatt gtaatgtcat agatttccat aaaaattcct cccttttcac
    26701 actatagcag aatttaattg agaatgcttc tcaaaaatgt ttgaattcga aatcgaaacg
    26761 gtaagttata gaatgtatct agtgatgaaa aataaaagaa aacaaatcta gtatttttac
    26821 gagaggttag gtattatgtt attattatta tgaagtatgc aaatattagg aggaaacaat
    26881 atggcattcc cacaactaga tttaaaaagt gaaaaaggac caaaagctgt tatcaaaaca
    26941 aaccgtggtg acattactgt tcaattattc cctgaactag caccgaagac ggttcaaaat
    27001 ttcattgaac tttccaaaaa aggttattat gatggcgtga tttttcaccg cgttattcct
    27061 gatttcatga tccaaggcgg cgatccaact ggaacaggaa tgggtggcga aagtatttat
    27121 ggcgaaagtt ttgaagatga attcagtcgt gaactgttca accttcgcgg agctttatct
    27181 atggcaaatt caggtccaaa cacaaacgga agccaattct ttattgtaaa taacacaaat
    27241 gtgccagcta atatgcttgg acaactagaa ggtgctggat tcccatcaga aatcattgaa
    27301 gcgtataaag gtggcggaac tccttggcta gatttccgac atacagtctt tggacatgta
    27361 ctagaaggga tggacacagt agatgaaatc gcaaatgtac aacgtggtcc acaagaccga
    27421 cctgtacatg atgtagtgat tgaaacaatt gaaatttcag aatagtttgg tatggtacgg
    27481 agtaattatg aaaaaggacg aaacctagta aggtctcgtc cttttatttt gaataaatga
    27541 tttaatcgat tgtctctaaa gcatacttga ttcgattaag tccttccagt aaagtttctt
    27601 ctggacaagc aatattcaag cgcatatgcc catgaccgga aggaccaaac gtgatgccag
    27661 gatttaatac gacttttcct ttccgaacaa gagtgttctc caattcttgg tcgtctgaaa
    27721 tataggcggt aaaatctaac cacattaagt aagttccttc agggttcatt attctcactt
    27781 tcggaagata ctgttcaaaa aactgattaa ctgtttgaac atttttttct agataaggaa
    27841 tcagttggct taaccattct ccacccgtct cataagccgc ttgggttcca atcagtccaa
    27901 aagtgttgat ttcgtgctgt tggttcatca ctaaatgttt ttcaaaatca gctttcatct
    27961 ctggattttt gataaatacc attgaatttt tgattgcagc tagattgaaa gtcttggttg
    28021 cggaagtaaa agcaactagt agatcatcta aattaggatc aatcgttagc atggaagtaa
    28081 atgtatgatc gaataaagtt aaatcttgat ggatctcgtc actaaacaga atcacttgat
    28141 gttttaaaca caattcgctt aactgtttca attcttcttt gctccaaaca cgccctccag
    28201 gattgtgagg attgcataaa atcattgctt ttacattgtt ttcttcgatt tttttctcca
    28261 tgtcagacaa gtccatgatg aaatgattat ttttttctag caaagagctt cgaacgatgt
    28321 gacgttgatt tgtttctata atagaggaaa atggaggata aactgggtca tgaatcaaaa
    28381 tagaatcgcc tggttttgta aaagtttgta ctgctgcagc taaactggtt aacacaccac
    28441 ttgtaaaaac gatattttct ttcgtcaact ccacagcatg gtgttggcgt tcccaatgaa
    28501 tgatagcctg atatagttta tcagacagag tggcataacc aaagattcca tgtttgatgt
    28561 attcactaaa cgctttagct accccaccgg gagacaagaa gtccatatct gctacccaca
    28621 aaggaagtaa gtcatccatt tgatatgtct cagcaattgc gtcccatttt acactttctg
    28681 tatcttttct tgaaatctgt ttatcaaatt cgatcatctt aagacctcca gtcattttcg
    28741 tcgcttcttt ttttgagcta tttacagtat aatgataaat gcgaagagag ggaagtagat
    28801 gacttataaa attggacaaa taattgaagg aaaagtgaca gggatacagc cttatggcgc
    28861 attcgtttct cttgataacg agacgcaagg acttattcat gtttcagaag tacaatccgg
    28921 ttatacgaaa aatatccatt cattgttaaa agtcggacag ccagtaacag ttcagatcat
    28981 cgacattgat gaatattcca aaaaaatcag tttatcttta agaacgttag aaaaaacaaa
    29041 tccagctgtt ccatatcgca gaaaaaggta tttcacgaat aaaaatcgta agatcggatt
    29101 taccactatt gcggagcagt tacctatttg gatagaagaa gcattatctg aactagaacg
    29161 gaaagaaaat aagaaataaa aagtgtattt tttctgaaaa tgtgctagaa tttttatgta
    29221 agccatagaa caagttgatc gaggtggaaa ttttggcaag caaaagagtt gctggtacaa
    29281 ttatgttgca tttggaggat ggtactaaaa aatttttggt ccattcaatt gatgacaagt
    29341 tggaatttgc gttagcggaa ctttctgaag gaaagactgg tttagcgaat atacttaatt
    29401 tcttaaaaga aatagttcat atcgatgtta gcaagattag tttgatggaa ttgacaaata
    29461 cacatattaa agaggaaaat gttccgttgt ttgtctttga aactgaacaa aagaatcaaa
    29521 gagaagaatt aggcgaagga tatatttggg aagaaccagg tcaaatgcgc tctgttcttg
    29581 gaacttacga agtagaggga gtgcctttct tctaaaatac agattaagcg aacaaagaag
    29641 tttgaatttt tttcaaactt ctttttttat tgtttggtcc aaaaaataca atgaaatgtt
    29701 ctgctaaaga tagtttttta gtgcatttta ttttcaaaat atgttgaaaa cggttgtata
    29761 acgaataata ataattgatc gaaaaatcat ttcacaaagt aatgcttaat ttatagttga
    29821 ccaaggaaga aatacatgat aaatttaaca gcgttgattc tgaagtggat gttatatcac
    29881 atttctaaaa aatttaaaaa atagttattg acatgttact aacgacatga taagataact
    29941 gagtcgtt
//
LOCUS       DBGZHO010000027        29606 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.027, whole genome shotgun sequence.
ACCESSION   DBGZHO010000027 DBGZHO010000000
VERSION     DBGZHO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.027"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="ACN3HL_001447"
     CDS             <1..1350
                     /locus_tag="ACN3HL_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HHC8006334.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="ACN3HL_001448"
     CDS             1484..2827
                     /locus_tag="ACN3HL_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HHC8006335.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="ACN3HL_001449"
     CDS             2939..4390
                     /locus_tag="ACN3HL_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HHC8006336.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="ACN3HL_001450"
     CDS             4739..5371
                     /locus_tag="ACN3HL_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HHC8006337.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="ACN3HL_001451"
     CDS             5959..7398
                     /locus_tag="ACN3HL_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8006338.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="ACN3HL_001452"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="ACN3HL_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            8160..8375
                     /locus_tag="ACN3HL_001453"
     CDS             8160..8375
                     /locus_tag="ACN3HL_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006339.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="ACN3HL_001454"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="ACN3HL_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9035..9946)
                     /locus_tag="ACN3HL_001455"
     CDS             complement(9035..9946)
                     /locus_tag="ACN3HL_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8006340.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="ACN3HL_001456"
     CDS             complement(9965..10969)
                     /locus_tag="ACN3HL_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HHC8006341.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="ACN3HL_001457"
     CDS             complement(10966..13089)
                     /locus_tag="ACN3HL_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HHC8006342.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="ACN3HL_001458"
     CDS             complement(13094..15541)
                     /locus_tag="ACN3HL_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006343.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="ACN3HL_001459"
     CDS             complement(15528..15917)
                     /locus_tag="ACN3HL_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8006344.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="ACN3HL_001460"
     CDS             complement(15977..16480)
                     /locus_tag="ACN3HL_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHC8006345.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..16714)
                     /locus_tag="ACN3HL_001461"
     CDS             complement(16493..16714)
                     /locus_tag="ACN3HL_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006346.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16719..16856)
                     /locus_tag="ACN3HL_001462"
     CDS             complement(16719..16856)
                     /locus_tag="ACN3HL_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HHC8006347.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16853..18037)
                     /gene="mobT"
                     /locus_tag="ACN3HL_001463"
     CDS             complement(16853..18037)
                     /gene="mobT"
                     /locus_tag="ACN3HL_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HHC8006348.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(18296..18586)
                     /locus_tag="ACN3HL_001464"
     CDS             complement(18296..18586)
                     /locus_tag="ACN3HL_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006349.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="ACN3HL_001465"
                     /pseudo
     CDS             complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="ACN3HL_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19794..19958)
                     /locus_tag="ACN3HL_001466"
     CDS             complement(19794..19958)
                     /locus_tag="ACN3HL_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006350.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19951..20625)
                     /locus_tag="ACN3HL_001467"
     CDS             complement(19951..20625)
                     /locus_tag="ACN3HL_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HHC8006351.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20703..20915)
                     /locus_tag="ACN3HL_001468"
                     /pseudo
     CDS             complement(20703..20915)
                     /locus_tag="ACN3HL_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21036..22895)
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001469"
     CDS             complement(21036..22895)
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001469"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HHC8006352.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
     gene            complement(23610..24755)
                     /locus_tag="ACN3HL_001470"
     CDS             complement(23610..24755)
                     /locus_tag="ACN3HL_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HHC8006353.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            complement(24838..25173)
                     /locus_tag="ACN3HL_001471"
     CDS             complement(24838..25173)
                     /locus_tag="ACN3HL_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HHC8006354.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(25183..25557)
                     /locus_tag="ACN3HL_001472"
     CDS             complement(25183..25557)
                     /locus_tag="ACN3HL_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8006355.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(25570..25884)
                     /locus_tag="ACN3HL_001473"
     CDS             complement(25570..25884)
                     /locus_tag="ACN3HL_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8006356.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(25997..29224)
                     /gene="fss3"
                     /locus_tag="ACN3HL_001474"
     CDS             complement(25997..29224)
                     /gene="fss3"
                     /locus_tag="ACN3HL_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HHC8006357.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
BASE COUNT         8942 a         5919 c         5211 g         9534 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattgg gcattggtta
    16681 aaaaccattg atataaattt tgtccgaaat tcatcttgtc actttccttt cttttccatt
    16741 gctcgatccg ctgctgcact tgcattcatc aagcacatca cagtaacacc aagcatactg
    16801 ccaccaaata ccaaaaaaat atcttttaca attcccatga cgattcctct tttcatataa
    16861 tcaaattttc aattgccata ctttgttgct ccaaaatctt tttatgtcgg tctgataagc
    16921 gtgcattctg taccatatcc tggatatagg ttgtccgatt caatcgatcc aactccttag
    16981 ccattttcca cgtaggggcg acttgtcggc ctagccaatt caaggttcgt tcaatggtat
    17041 acggttttgg ctcggaagtt aattgaatct ctttccgatt ccgtccaata aaacgccccc
    17101 attgttcatt caagggccag ttggttcgcc ttttaccttc tactttatcc gcaaatcgca
    17161 agtaacgatt gataatggaa aacgtggtgc tctcaatgct acgacctttt aacaaatctt
    17221 gaatcgcatg aaaagcacgg tcatttttca gtcgaatctc aaaacgattt ttcgtctcag
    17281 tttggtctaa tggaatccct aacttgatat attgttcata gtctttttca tacaaacaga
    17341 aataaacctc actcttgaga ctgccgatat ataaggtatt gcccatgccg tccttttcat
    17401 cagcctttaa aagttccccg gaacgataac ttttaaaggt acgaaacaag gagatacatt
    17461 cttccttctg acattttttc gttagctcag gtatatccaa tagccccact cgatcattga
    17521 ttgccaagtc caagcgtttc atcacgccac cggcctttag acaatcctcg aaaaagtcgt
    17581 accagctacg cttttgagcg agtaaaaaag tttcaaattg tcggcaacct cgccccttta
    17641 attctaaaag cacaccttta tcttcttcat gagacaacat caccacaata tcacccatga
    17701 catactgttc ttgataggag taaaaggcat aatcttcatg gagcatatac tcaaatttca
    17761 aatggagaat ttcttgaata atttttcgtg catccgttgt gggaaagcga atccttacat
    17821 agtcaaacag taacgtcaaa ggcaaatcgg gattaaagct ttccagttgg tcaaaaattt
    17881 tcctcatggt ttttatagat gcggttacgc caccattttc tatctgattt aagtacggcc
    17941 gactaagtcc acaagccgta gccaatttat tttgtgaaac gccgtattcg ttgcgtcggt
    18001 cttttaatag ccgataatct aaattccgtt gtgccaagtt ctcacctcca aattcaaggt
    18061 gttaactttt tcaaatgagt taacacctat acaaattact tactatcttt gatacaacaa
    18121 gcattcttaa tggttgctta cttatttttt gtgtttttgt acccccctgt tagatacggg
    18181 ggtgagacat catggtcggc taacgccgtc catgaacagg cacagcacca cggaggattt
    18241 ctgcttcgcg aatcctccgc ggtcagcgcc taacagtcag ttgtgttggt ttaggttact
    18301 catctgtaat accatttact tccaactctg ctttcatttc taacaagtat tgacgaatat
    18361 ctggttcttt tgcttggtcc gcaatccgct caaattctgc aattacttga tttatttcaa
    18421 ttcgagcatc cgtctcctca ttcattaaat atggatcgcc agcgactttg acaccattct
    18481 tgcgaatatc aaattttaac cgtcgcaatt gttcttctaa ttctgggtct gactgaatct
    18541 ttccaatcac ccaataaatt tctccaatca actcatcata aaccatgtac atccaactct
    18601 tttaatcttc tggcaatatc aaaaatgacc ggaactgtta cagagtttcc ggcttgctta
    18661 tacaactgac tatctgaatt gacttgagaa tctcgatcaa aagcccaatc gggaaagccc
    18721 tgaagtcgcc aacactctct aggtgttagc ttccgaattt gatactgatc cgtgacgatc
    18781 gcttgttggt ctcctgttag taaggtatga acactctgtt ttcccagacg acctcggcga
    18841 cttgtggaat taggaaaagc cagattcaca ctgtcttctg gcttcacctc ttgatattct
    18901 gtttcatttt ttcgaatcat gatttttgta ccaccttgtt tcgttgacaa ggtgggggcg
    18961 gttccagtaa cttcataaac tcgattacct tgttcaaact ttcccggtaa tagtcctgct
    19021 acagagattc catcccttgc tggcagtgcg attttgattc cttcatcacc tgttaaggtt
    19081 ggcgctacgc catctgaacc atagacttgt ccacccattc ctcgattgga aggattgata
    19141 tttaccaaat ttctgatgtt ttgatcagat gttgaagacg gtccaatgat aggaaatact
    19201 tgttcggtac atgcgtctcg agaatgtccg ataaggaata tccgctcccg gctttgggga
    19261 atgtaggcct ttgagttaag cacctaccac tccacgtcat accccaatcc atccagcgtt
    19321 cggaggatcg tctcgaacgt agcccctcct tcgtgattga gcaatcctcg gacgttctca
    19381 aggaataaaa gcttaggtcg gagaagagtg gtgaaccgag cgatttcaaa gaataaagta
    19441 cctcgagtat cggaaaatct ttgccgcttt cccgcaattg aaaaagcttg gcacggaaat
    19501 ccgccgcaaa ggatgtccac tggtccgagg gattgaataa actcatctga tacacttgtg
    19561 atgtcatgca tttccacctc cttacttgta tcatgaattg ctttataact acgtctagca
    19621 aatttatcaa tttcacaaaa accgatacaa tgatggctcg cctgttccat acctaaacga
    19681 aagccaccaa taccggcgaa taaatctaaa aatctcatac attacctcat tcattgcaaa
    19741 gaaaaaagcc aagaacattt tgctcttggc tcatacatta ttaatttgtc ctactatttt
    19801 ttatttaatc caactaattt ccgttgtttt tcattggcct gatcggctac atatttaatc
    19861 accgttttga actcttttgc agtagcattt tccgataaat ccgcaatgct cttattgtat
    19921 ttctttacaa ttttcgttac ttgttctttc tcagtcatgt aattgaacct ccaaatcttt
    19981 cctactatac cctagtggta aaaataattc tagattatcc gtagcataat gaacttcgga
    20041 aatattattc gtataatctt ttattatgat atgaagcaat acatctggat gtttactctt
    20101 tacttttgca atgttctctc ttgatttgaa aaaagcgtta ataaatgcct ttttcggcac
    20161 atgacgtccc tctgcaattt cacgttcttg tgtaaatttc caagcgattt tagggtcttg
    20221 ataaacatag aaaatcgtca ctcgaaaatg ttttttcaac gcccgcgaga tatttttttc
    20281 agcacttaat attgcaaaag ttgcatccag aataaaagaa tagccatgat ctaagacata
    20341 tctaaatgcc tgctctacca accaagaaga tgctttttga aagagactag agttttttcc
    20401 attataatca ggaaactggg tgcgaaagta atccgcatca ataatcacat ggttatcata
    20461 attctcagct aatccaatgg caacctctga ttttccagcc ccaggactcc ctgccataaa
    20521 aactgcgtct cgtccaactt cgggggattt ccctttgata atataagaaa taaacttatc
    20581 cttatttgct tttgcatact ctaaataaga atcattactt tccatattaa ttatcccctt
    20641 tcttcctact atataaaagt attatacgtt acttgaagta taaagtcagt attgaagatc
    20701 actcaatcat tcatcttttc taatttacta attgaatcta agaaatcata cccttttggt
    20761 acaagtggcg tataaaactc actaatcaca ctgccacctg tatccacata acctcgacct
    20821 ttgatgtgct tcataaagaa gtttttttcg acctccccaa acatcatgga atatccgagt
    20881 tcactcatac gacccaaagc cacgcgaaag ttgaatagcg ataggtaatc ctttgatgtc
    20941 atctccagat tttcccccgc ttcacaccgt acatgaaact ttcacttcat acggcgttcc
    21001 atcaaaagaa tgttaagtat gatatatttt tcaagttaaa ctgttaaaac actattacca
    21061 gctttgacac gtaattcatt tagtttttct atttgttcat tggttagatt taatacattc
    21121 aggtatttgt gtatgatttt ttcttcgata gcatggacta atgcgtgaac atttttgtga
    21181 ataataatga ggttgctgta tttgtctgta ccctgttgtt ttactggtac gatatggtgg
    21241 caatggattt cttcgtattc gagaaattta cccgtgatag cacattttcc cttttgagca
    21301 gaatatttag atattctgtt atccacaaat tcaatacttc tttcataatt actatttctc
    21361 atcatgtgaa gtaaaagggc taggtctaat tttaatttac tgtgtatctt gcttcgtcca
    21421 ctttcagtgt acttgcaagt tccctctgat agggggacag caagtctaaa ctgaacatag
    21481 ttgagcggta caattggcac attattcaac catcgcattt ctttactttt tccatacttc
    21541 gatttgataa atgtatttaa tatctttcca tgtttctttg tcggcagttt gtgattgatg
    21601 aacggtttta gtgtataggc tattttactg caatcgagat ttacacaggt tgcaattcca
    21661 taatattgat ggattccaat caccatagaa ttatataatc caatttcttt tgcttgttcg
    21721 caatgattct tcggtctggc aactttacgt aattgtttct ttaattggat tttaactctt
    21781 gtcattgatt ttttgctcat atgactttcg actacgtatt ttttaccttt cttgattagc
    21841 tttaattcaa atcctagata ttctgattta ccttttttga gattgacaat tttggatttt
    21901 tcttcgctaa tttcaagtga taaccgttct ttaagccaca ttttcgttgc gtgaaatatt
    21961 ttatctgcat gacttcgttt tctacaaaag attttgaagt cgtcagcata ccgaacaatg
    22021 tatatttctt ttaagtttgt tcgtcttaat gcccgatact gattagtctt atcaatgcct
    22081 ttgcctttat ctcgcctatc cataatcttt tctgtctcaa tcgtggtatt ttgccattgt
    22141 gaagcaaccc accaatctaa ttcattcaat atgatattag atagtaaagg ggataggaca
    22201 ccaccttgag gtacaccttt tttagggtgt tcgactttac cggttggtag gactatagga
    22261 gcatttagca tggatcgaat aatacctaat agccatttat cacggattcc aatcgtccac
    22321 atttgacgca aaagtttaga gtgattgaca ttatcaaaga atcctttaat atcaacatct
    22381 actacaaagt gtagcttccc cctatttgcc agtcgattgc aggtagcaat cgcatgatgt
    22441 gtggaacggt ttggtcgaaa tccataacta taattgtgaa atttagcttc gcatatcggt
    22501 tctaagactt gtaaaataca ctgttgtatt aacctatccc agattgatgg aatgcccaga
    22561 gggcgtgttt ttccatttgg tttgggaatt tctacacgtc taactgctcg tggtttgtaa
    22621 cagcgaaaaa gaactttaac ctcagttaga aaggtatctt ctgacagtgt tttaatgtct
    22681 cgaatacttt tcttatcggt actcgctgta taactgccct tgttattctt gatatttctg
    22741 tatgctagtc gaatattttc atcactcata ataattgtca tgagctctgt aaaaacttct
    22801 tttttatcac tttttacata cagttcatca aatatttgtg tcatgccata gtattcacta
    22861 tgacgaagtg ttttatttgt ttttacttta ttcatagcac cactaccttt gtttacttag
    22921 gttgtagtgt ttattttgtc ttactcgatt ctatgaaata catcatttaa ttaacgattt
    22981 cttttgacta gtggctattc ctccgatata tttctatatc ctcattggta ctgtgccacc
    23041 actttcactg gcataaatgt gcttattatt cttcgtcaca aatgtttcaa tggaatatag
    23101 tttcctccac attgccagct tcccatgttt cgatattttt atctttatat atacttttag
    23161 gtgcttgctt tgaacctgta tatttccaat gcctgtaaca ttgcatggtt gttcataacc
    23221 aataatctta ctaaaccaca acatacattc tgttccgttg atacggtaga atcctgtaca
    23281 tttctataca gtccgtgtat agattctttc attcgcaagt tcgtcagtag tattacttac
    23341 attctcaccg tgagtatttt atagacctcc gacctatagg ttacatcatt cacctctgaa
    23401 caactttcgt atatgaattt atcatattta cggtaacttt cagccgactt caccgagctt
    23461 ctgaccatct aacagctata tgttaaacag ccagtcggag tattaaggga gcgtttcagg
    23521 gcgttacccc atcattccac tgctcaaaat atcagttctc cttaaaagga aacttatgtt
    23581 ttcttctttt aagtgcctaa ccttttcagt tagaaacatg tcgcacattg atcgcggatt
    23641 ccgtctccta aatatttcgc atccggcctt tggcaagcca aaatcagaaa gaaaccagat
    23701 tgacgaccca acatcacgat ttgtttgagc ttattcaaaa tcaccgcact ttctttcgtc
    23761 gttaacatct ccatataagc cacgtattca tcaaagatta aaaagttggg tggaagtcca
    23821 agataggcat aattctctcc tgttttgtag ttagacattt ctttcattgc cttgctacga
    23881 gccatcatac gttcatagaa atcttccaca caagcagaaa tttcttcctt ttgtgaataa
    23941 acatgaggca tcaccgtacc taaatcagct aaatctgcat ttttgggatc gaggataaac
    24001 aattctgcat ctgacttcaa tagtgcttcg ataatggtga ggaggaaata ggtcttccct
    24061 ccacccgtgc caccagcgat taacatatgg ggtaaagaat cataagccca tacttgattt
    24121 ttcatcaatc gcagagtccc attttctgcc actacttcgt ctatcccaat tcgattggcg
    24181 atcatatcat acagtaaagt atactccaca taggagtctt tgagttcctt ttctactaac
    24241 tcacaataca gtccgctttc taacttcttt tccaatttta aaagctgatc ttggtatttc
    24301 ccaagtgaaa tttgaacgcg aatagacagt aatccatctt tcattcgata atagattttg
    24361 gggaagtaac tgatagtctc tctggttcgg ctactattca aatctttgaa aaagccttca
    24421 ctttgagttt gtttcacttc ataccaatgg ttctctagaa tcatccgagc tagcttttgt
    24481 cgatgccaca agcttcgcca atgatcaaga aaaaagtgaa tataaagcaa tatcatagct
    24541 cctgaaaaag cgagacttcc aagcagacat actaaatctt ttatagacca aacgatttca
    24601 atagtagaaa gtgatagctt agaaatatca aattgtctaa actcttgaaa ataaaagacg
    24661 ctcatccaac cgatgaacag agcgagtagc cagccaagaa caaagtgata aaccaagtgc
    24721 tgatctcctg cgcgtatgcg atgtcctttg tacattttga tggtttccac ctccaatcga
    24781 aaaagcccaa taggatttca ttaggcaatt tcaaaaagtt atgctagtca tttactgcta
    24841 cgaggagggg agttgtttcg tttcaaccaa ttgatttaaa aagccttcaa tagcatccgg
    24901 catctccaca ccaatttctt ccaaaatgga ttctgcctgc cgacataagt tttcatttac
    24961 ttcgacaact ataaagaaag actcttcttc tcctaaccag tctagtacat cagagtcttc
    25021 ttcactgtcg ctattttctc caagtaaacc ttgatgtata atcagaaaca ttttttcatc
    25081 agaggttaat gctttaacga gttgttcctc agtcagctcg ccttttccat attgatcgag
    25141 acaatctaaa atatgttcaa cattaatttc cataatcttc acctatttct ttctttcatt
    25201 ttggttcgta ggatttcctt gattcggctg ccgcttcaag actaaatcat ccgccttaat
    25261 gaaccaatta acggtagttc cttctcgaaa aacataattg gcaacggtat ccacgattgg
    25321 attgaccaac tctacctctg catcataagc aaactcgcgt aagggtacat tagctgggat
    25381 actaacttga atcattcgcc cttgtgcaga ggattttaaa ttataggttc gttcttttac
    25441 ctcattacca attgttccat cctcattttg cttccgtact tctcggcgta atgcggaaaa
    25501 acgcaacttc ccaaatgtta aacctgaatc tacgacaata ccttctgtta atctcatctt
    25561 cttttcctcc tatgctttca ctaaatcatc aacatacaac acgtaatcag taaacccacg
    25621 attctcaatc tcatagcctt tggcaaccaa atggggattc acggctttta gcggttggtc
    25681 ttgatcaaaa tccttttcac cggcttccgc agctactacc acctcaatat catcggcccg
    25741 ttgcttactg gaatacaaat gataactgcg accaatcacc gtagtattcc gtccatatcc
    25801 ttctgttata atttctcctt caccggcata acttaacttt ccaaaggttt cagccatatc
    25861 tggcacgaca aatttcaatt ccatcttctt ttcctctttt cattgttagt tttggataca
    25921 aaaatagcgc gactactttt ttaggaggcg gtcgcgcacg ttggttctta ggatttactt
    25981 gtatcatctc atcaccttag ttccggcgat tccagaaata atagcccgcc gtcgcaaaaa
    26041 tcaaagtaaa accaatgaac agtaaaacat tggaattttt ctccccggtt tgagggaagg
    26101 tcttcactgt gggactagat tcttgagagc cacttggaac agttggtgtt tccggttgtt
    26161 tcggcgtact tagtatggtt ggaacttctt ttggtgttaa ggtttgagat ttttctttca
    26221 aatcttcatt gtgttttcca ttgatattcc catctttatc gtaattgatt tccgcaaaag
    26281 taaacttggt tccttctgga tattttccgg tatctacttt tttcgcaagc acagttttgg
    26341 tgaattcttt atcatttact tcataatcaa tcttgccaga tttccaaatt tctttgtttg
    26401 taccatccgg taataaagca tacagaattg tttcgaaagc ttcttttgag ccatccagta
    26461 catcatgagt aatcgacaca tcatcaaaca tatccaccac atcaccatga gtaaaggtct
    26521 gagaaccgtt ttctaggtgg gcctttgttt ggatagaaac atggtgttcc actgtacaac
    26581 tgacagtttg ggcttggtta ttcaagctaa catccttcgc tactggctta tcgcctgctt
    26641 caaaagcttc cttattttca tacacatagt tgaataagac aatagtttta tttaaaactt
    26701 gttcggcggt taatttatgc tgaattttcc aagttcctgt tttctctttg ttcgccaacg
    26761 ttgcgcttgt ttctgcaatc accactggtt tggctttttc atctttttct tgggcagctt
    26821 ttgtcgcatc cacatcaatg gcttgcgcta ccacatacca gtcttctttg atttcatgta
    26881 gattgtaact caatttatca actagctcgg tagaatccag agaagttaat tctttgtttc
    26941 cgtctttcca agtcgcaaga gaagttaaac tatcttcttc ctcaggcaaa tcatagagca
    27001 ttaaacggtt caaactaaca gaaaatgctt tgttcgtcag cttctcgtaa ggaacggtca
    27061 ccgttttaat tggttgtttt tggtcttgtt cggtaatggt aaagacatac tcactcttca
    27121 caaagtcttc tttgttttcc ttaaaagtag aacggatttc taatggcgta atcttttgaa
    27181 aaccttctgg ggcttctact tcttcaagta aataatcccc ataaggaaga ttttcaaact
    27241 tgccataacc atcaaaccct aattgctcgt tataagctgt ggtcgcttca tcttcggcac
    27301 ctgtgatttc attggtccct tccaatggcg acactttaaa ggtcagatca ttgaagccag
    27361 tttcggtagt gcccgcagct gatccagcaa atttaaagaa atcaaagcca aagcgaatca
    27421 cttgttcttt tgccgtaaca tttcgggtaa tcacggcatt tttttcgcta tcatccacct
    27481 ttttgatgga tacaggatac tttgtttcat caaggctata tccttcgggc gcttttgttt
    27541 cttgccaata atactcgttg atagctaaat gtttaacggc aacttggttc ttttcgtcta
    27601 aagtcaaagt gaccgtttca tcagaagctt tcgttccctt cgctaactct ggtttaaaag
    27661 cctcactcca tttaacagct tttccatcct tagcagtaaa caaggtgtat tcagcaccct
    27721 caaagactgc cttaccttgt gctttatccc cagtatcttt gtcttctttc gtcaaagtgg
    27781 tttcgccagt gacttcttga ttttgccctt ttacgttact ggtaacaagg gctacggttt
    27841 gattggcata cttcaattcg acttttacag gtttgaacgt attcacgaac ccatgactag
    27901 ctttagtttc ggtcacataa taggttccca attccaacgc attagcaatc tcttttggtg
    27961 tttccgcatg accgttttca tccgtggtca tttcttgaac gatttcaccg gttggactgt
    28021 ctttgcgaat ggcaaacgta ttaccagcta aggaataatt gtcattccaa agatcactcc
    28081 ctgtttcaac tccgctttta tccagaatga tttgcccttt ttcccgtgcg ttttttgaag
    28141 tcacgtaaat ggtttcgcct gctttaatgg tggtagtcat gggggtggta tcaatcgtat
    28201 aaggcgccgg tactgatttt tcggtaatgg ttacttttgt accatgagga atctcatcca
    28261 atgtagcaat gccttctttg tcagtagtca cgtcttttgc aggtaaagtt tttccaaagt
    28321 ctaaatggaa aaccgttcct ggtacaacat cacccgattc tttatcgact tttttgatct
    28381 ttaaagaacc ctccgtttcc acatcaattt tgattgtgta ggtattaggt ttatcaatcg
    28441 ccccggccat taaagtctgt tggccagcct ttttataggc gacaggtgtt ccggtaccag
    28501 cagatttctt aagcgtcagc acaccacttt cttttgaatt ggcatttggg gtgattatca
    28561 actgattacc attcacacga taatcaatgt ttgcggcatt ttccacaacc tcatcgaact
    28621 ctgacaaatt cagattattc gtatccgtca cagtagtcga ttgccctaat actgttttag
    28681 ccgtactatt atggaaggtt ggtttcttct gataatcgtc aatggcttga tttatttttg
    28741 cctcaatggc tgcgatattt acggcactac catctgatcg ttttattgag tgaagggtat
    28801 acccattaac ttcttgccag atcatcttct gtgccacaat atgagtatct gcatctgtac
    28861 ctactttttt ccataaaacg gaaactaatt tggctttatc ggacatatct ggtaacgggt
    28921 ttttctcata gccaggagtg aactcattgt aaatcgggac tcctggttca atacagaaaa
    28981 tatcttgttt aaagccgttg tacactgcat aatgcggaac agtgacttct gacattggac
    29041 gaccatcact aaaagttcct tcaacagcat attgatgtgc taaatctagt tctacggtta
    29101 ccgtttgtgg atgggtaatt tcatcagcaa aagtaatcgt aggagcaatt gctccaacaa
    29161 ttgcttgaac agccaaactc aaaatagtta atacacataa tttctttttt tgttttttat
    29221 acatgaaatg ttctcctttc aaattaagca caaaaaaata agatgctcgc ttgaacatct
    29281 ttgtttataa agtcttttta aaatttttat tgactgaata gaatggattt gagaatgaat
    29341 gagcctaaaa atttaatcta aaatacgaaa tatactgcct ttaaattaga acacatttta
    29401 gaacacaaac atttcaaatt taatcaaata taataaaata tatttacggg aaaaccttta
    29461 taaatcaagg tttttcaaac ttattcaatg atacgaagaa aaaaccaggt cttaagaaag
    29521 ctcgtaaagc atctcaattc tcaaaacgtt aatatccttt atatatcaac gttcaagacg
    29581 ctttccaatt atttggaaag tgtctt
//
LOCUS       DBGZHO010000028        29217 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.028, whole genome shotgun sequence.
ACCESSION   DBGZHO010000028 DBGZHO010000000
VERSION     DBGZHO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.028"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1028)
                     /locus_tag="ACN3HL_001475"
     CDS             complement(<1..1028)
                     /locus_tag="ACN3HL_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8006358.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1110..1799)
                     /locus_tag="ACN3HL_001476"
     CDS             complement(1110..1799)
                     /locus_tag="ACN3HL_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HHC8006359.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACN3HL_001477"
     CDS             complement(1905..2273)
                     /gene="rplL"
                     /locus_tag="ACN3HL_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HHC8006360.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACN3HL_001478"
     CDS             complement(2326..2829)
                     /gene="rplJ"
                     /locus_tag="ACN3HL_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HHC8006361.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3033..3160)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACN3HL_001479"
     CDS             complement(3239..3928)
                     /gene="rplA"
                     /locus_tag="ACN3HL_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HHC8006362.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACN3HL_001480"
     CDS             complement(4032..4454)
                     /gene="rplK"
                     /locus_tag="ACN3HL_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HHC8006363.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACN3HL_001481"
     CDS             4797..5465
                     /gene="sdaAB"
                     /locus_tag="ACN3HL_001481"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HHC8006364.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACN3HL_001482"
     CDS             5478..6350
                     /gene="sdaAA"
                     /locus_tag="ACN3HL_001482"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HHC8006365.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6441..7541)
                     /locus_tag="ACN3HL_001483"
                     /pseudo
     CDS             complement(6441..7541)
                     /locus_tag="ACN3HL_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7633..8520)
                     /locus_tag="ACN3HL_001484"
     CDS             complement(7633..8520)
                     /locus_tag="ACN3HL_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHC8006366.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACN3HL_001485"
     CDS             complement(8597..9142)
                     /gene="nusG"
                     /locus_tag="ACN3HL_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HHC8006367.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACN3HL_001486"
     CDS             complement(9243..9413)
                     /gene="secE"
                     /locus_tag="ACN3HL_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HHC8006368.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACN3HL_001487"
     CDS             complement(9437..9589)
                     /gene="rpmG"
                     /locus_tag="ACN3HL_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHC8006369.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9751..10395
                     /gene="cbpA"
                     /locus_tag="ACN3HL_001488"
     CDS             9751..10395
                     /gene="cbpA"
                     /locus_tag="ACN3HL_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HHC8006370.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10451..10954)
                     /locus_tag="ACN3HL_001489"
     CDS             complement(10451..10954)
                     /locus_tag="ACN3HL_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HHC8006371.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10967..11013)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11551..12516
                     /locus_tag="ACN3HL_001490"
     CDS             11551..12516
                     /locus_tag="ACN3HL_001490"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HHC8006372.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12615..13787)
                     /locus_tag="ACN3HL_001491"
     CDS             complement(12615..13787)
                     /locus_tag="ACN3HL_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006373.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13774..14919)
                     /locus_tag="ACN3HL_001492"
     CDS             complement(13774..14919)
                     /locus_tag="ACN3HL_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006374.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14933..15865)
                     /locus_tag="ACN3HL_001493"
     CDS             complement(14933..15865)
                     /locus_tag="ACN3HL_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006375.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15982..17061
                     /locus_tag="ACN3HL_001494"
     CDS             15982..17061
                     /locus_tag="ACN3HL_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HHC8006376.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17058..17687
                     /locus_tag="ACN3HL_001495"
     CDS             17058..17687
                     /locus_tag="ACN3HL_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8006377.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17797..18024)
                     /locus_tag="ACN3HL_001496"
     CDS             complement(17797..18024)
                     /locus_tag="ACN3HL_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8006378.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18127..20715)
                     /locus_tag="ACN3HL_001497"
     CDS             complement(18127..20715)
                     /locus_tag="ACN3HL_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HHC8006379.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20735..21394)
                     /locus_tag="ACN3HL_001498"
     CDS             complement(20735..21394)
                     /locus_tag="ACN3HL_001498"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHC8006380.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21443..21946)
                     /gene="trmL"
                     /locus_tag="ACN3HL_001499"
     CDS             complement(21443..21946)
                     /gene="trmL"
                     /locus_tag="ACN3HL_001499"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HHC8006381.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22167..23033)
                     /locus_tag="ACN3HL_001500"
     CDS             complement(22167..23033)
                     /locus_tag="ACN3HL_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HHC8006382.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23142..23783
                     /locus_tag="ACN3HL_001501"
     CDS             23142..23783
                     /locus_tag="ACN3HL_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HHC8006383.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23845..25206)
                     /gene="mgtE"
                     /locus_tag="ACN3HL_001502"
     CDS             complement(23845..25206)
                     /gene="mgtE"
                     /locus_tag="ACN3HL_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HHC8006384.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25224..26123)
                     /locus_tag="ACN3HL_001503"
     CDS             complement(25224..26123)
                     /locus_tag="ACN3HL_001503"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HHC8006385.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26125..26922)
                     /locus_tag="ACN3HL_001504"
     CDS             complement(26125..26922)
                     /locus_tag="ACN3HL_001504"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HHC8006386.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26900..27604)
                     /locus_tag="ACN3HL_001505"
     CDS             complement(26900..27604)
                     /locus_tag="ACN3HL_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HHC8006387.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27735..28310
                     /locus_tag="ACN3HL_001506"
     CDS             27735..28310
                     /locus_tag="ACN3HL_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HHC8006388.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28428..29105
                     /locus_tag="ACN3HL_001507"
     CDS             28428..29105
                     /locus_tag="ACN3HL_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HHC8006389.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8602 a         6181 c         5254 g         9180 t
ORIGIN      
        1 acagtattat ttcggttgct tgctgcttca cctagccctt gtactcgtgt ttgattggcg
       61 acttgaccaa attgattccc gacgtctaat aaaataatag ctaaaagcaa aatggccaaa
      121 tggcttccgc caaccaataa agcaataaag cttattgttt gcataacaag tcccatatac
      181 acgatttttc tttcagaata agaatctgcc agtcgtccca cgataggtgc agcaactgct
      241 ccagacaaac caaaaatcgc taatatccct gcttcgaatg ttccccaatt gtaggcggga
      301 ctgctgatat aaaaaatcaa cgtagaccaa aagatcgaaa atgttccaaa catgaaaaat
      361 ccactgactg ccgcttctct taatagacgt tgagaagcaa ctaaatgcgg caaactttta
      421 agtgaatcaa ggtatgaaac agctgtacta ctttgctgga cagaacgcgg cattttccag
      481 taaagcagaa gtgtaagaat tccgactgca cataaagcaa ataaatagat catccgccaa
      541 gaaaaaagac tggcaacaat accagatacc gtccgagaaa gcaaaatccc cacgagtaaa
      601 ccgctaagca atgtacccat gaccttccct cttgcttttg gtcccgctag taccgcaccg
      661 taaggaatga tgatttgcgg cacgatcgaa agtaatccta ttaaaaaaga agcgcatgca
      721 aataacgtaa acgaaggcgc aaaaaaagcg gccaacagag agacggcaga taacgctacc
      781 attcgaatga tcaattttgg acgatccacc acgtccccta aaggaactaa aaacagtaac
      841 cctaacgcat agcctaattg ggtcaacatc gtcaatatcc cgactgcact tgtgctaaca
      901 gataaactag ctgctacttt tgttccaatc ggctggatgt aatacatatt ggcaacaaca
      961 acgccacaag tgattgataa tagtaaaata agcgaagttg ttaaaggtgt tttttcatta
     1021 ctcttcattg atttccccca tttcctatct tagtttacaa cttatggaaa agattggaaa
     1081 tagaaaaata caactattcg ccacacttat tatttgtgct tttgttttcc ttgttttttc
     1141 ttgcgatctt tataaatgaa gacaactaac cctactagca cagtaacact tgcaaccaac
     1201 gtgactgcag ttttgttata tccgtgaaac agagcttctc caccacacgc atacaacaca
     1261 gacgaaggga tgactccaat cacgatcgac aatatgattt gctgtagagg caatttcatc
     1321 gcatctgcag caaaattgac catagaagat ggaataaccg gtatcatata gcctaacatt
     1381 acacctattt ttggatgttt catttgtcgg attgcttgca cccaatgatt cgtttcggtt
     1441 ttcttatcta aaaattttaa gcgatgcata aggaaaattg cagtgatgtt accaagagca
     1501 ttacccaaaa tgttgatgat cgcacctgtc agtggtccaa agctcaaacc agcaatgact
     1561 ccaactactg aagtaggaat acctggaaca gcacacatca ccgctgtcaa tacgatcaag
     1621 agtatcgatg caaaagtccc atgcgaacga atatgtgcga gtagctctgc cttactcgct
     1681 ctcggattta aaaataattg gatgtctgtc tgatattcta aatacaaccg atagcccact
     1741 accagtatca gaatgattcc caacgagatc aacatcaatc ggattatttt ctttttcata
     1801 tttcctcctg aaaaaaatct atattcatta aataatagtt taacataaaa acaaaaaagc
     1861 accgaaatcc aacataggat ctcagtgctt ttaaatagta aaaattattt aacagttaca
     1921 gatgcgccaa cttcttcaag tttagctttc aattcttcag cttcttcttt agatacgcct
     1981 tctttaactg gtgcaggagc gccatcaact acagctttag cttctttcaa gcctaaacca
     2041 gttgcttcac gaactgcttt gataacttta actttttggt ctccagctgc agttaattct
     2101 acagtgaatt ctgtttgttc ttcagcagca gcagcgccac cagcagcagc tacagctaca
     2161 ggagcagcag cagatacgcc aaattcttct tcaatagctt taactaggtc gttaagttct
     2221 aggatagttg cttcttttaa ctcagcaacg atgttttcaa tgttcaatgc cattataatt
     2281 tcctccgttt aattgttctt ttttatttaa tgctttatgc ggcaattaag ctgcatctcc
     2341 atcttctttg tctgccactg ctttgacagc gtaagccacg ttgcggactg gcgcttgtag
     2401 tacagatagc aacatagata gaagtccttc gcgatttggc aattttgcca atgctgtgat
     2461 ttcttccaat gaagagactt taccttcgat gataccgcct ttgatttcta atgcttttgc
     2521 ttctttagca aattcgtcca tgattttcgc tggtgcgact acatcttcgt tactgaatgc
     2581 aacagctgta ggtccagtga atacttcgtc catgccttca aggccagctt ttttagctgc
     2641 acgtgaaaga atagaatttt tgataacttt catttctacg ttagcatcac gaagttgttt
     2701 acgtaaacgt gttacttcat caactgttaa tccgcggtag tcaacgacta ctactgatgc
     2761 agctgctgta aatttttcgc ttacttcatc aacgattgct gctttttttg cgataattgc
     2821 ttcactcatt tttgagtttc acctcctgaa ttttgatgga agagtttttt gcactgaaaa
     2881 ggcaagtcac ttttatagtt actttgctca accagtatta ttcatcacct attcacttcg
     2941 ttcatagtga ttctactcgc tttgctcgaa aggaaactcc tttcgctttg ctcaaccagt
     3001 attgttcatc atctcttcac ttcgttcata gtgattcaca ataaaaaact ctatgccacc
     3061 gcagacatag agggactatt gaatatattc aataaacgtc ctcggtagga aattaaggct
     3121 tgatgccacc tactgtcttc ggtacaagtt aattattaac ctcaactagc ttagcatgct
     3181 aaactagttg agtcaagaat tatttttcag ttggatcaat caacattcta atatttaatt
     3241 agaaagaagc ttggtcaaca tggataccag gtccaaatgt tgttgtgatc gttacatttt
     3301 tcatgtattg acctttagct gctgatggtt tagcttttag caatacatca tggattgctg
     3361 caaagttttc aactaatttt tcatcgtcaa atgaaacttt tccgattggt acatggatat
     3421 ttccagcttt gtccacacgg taagttactt taccagcttt cacttcgttt actgcttttg
     3481 ttacgtccat tgtaactgta ccagttttag ggtttggcat taagcctttt ggtcctaata
     3541 ctcgtcctag acgacctaca gtagccatca tatcaggtgt tgcaacaact acatcaaagt
     3601 caaaccatcc gttttggatt ttttgaacca tgtcgtcgtc acctacgaaa tctgcaccag
     3661 ctgcttcagc ttcttttgct ttgtctcctt tagcaaaaac taaaacagtt tgtgttttac
     3721 cagttccgtt tggtaataca acagcaccac ggatttgttg gtctgctttt ttagggtcta
     3781 cgttcaaacg gtatgcaact tcaactgttg catcaaattt tgcaatgttt gtttcttttg
     3841 ctaaagctac tgcttcggca acaggataaa ctttacttga atcaactttt tttaatgcat
     3901 cttgcatttt tttgctcttt ttagccattt tggttcctcc ttgattgtgg ttataacggt
     3961 tgtacctccc acgtgttcta tatctttcaa tatagagcca actgagaagc tgctgtctta
     4021 gggtgtatag attattctac agtgatcccc atgcttcgtg cagttccttc aaccatgcgc
     4081 attgctgctt caacgttagc tgcgtttagg tcttccattt ttaattcagc gatttctctt
     4141 acttgatcgc tagaaacttt cgcaacttta tttttgtttg gttcgcctga acctttttcg
     4201 attttagctg cttttttcaa tagaacagca gctggcggtg tttttgtaac gaatgtgaat
     4261 gaacggtctt cgtatacaga aataacaacc ggaatgatca aacctgcttg atcagctgta
     4321 cgagcgttga attcttttgt gaatcccatg atattgatac ccgcttgacc tagtgcagga
     4381 cctactggtg gagctggagt tgctttacct gcaggaattt gcaatttaac gattttttct
     4441 actttctttg ccacgagaca tacctcctta agtccgtgat gtggttaatt ggagatgcat
     4501 atttctcctc ccacgtttta tctgatctga aaaaatccag acaaataatg tgcaaaacaa
     4561 tgcacactgg tacagtatag caaatttatt tgttttttca agattttttt ctgctatttt
     4621 tacattttgc ttgaataaac gctaaattta ttctaaaaaa acaacaattt ttcgttctca
     4681 tttcttcttt tatgttacac ttgcgctagc atggttcaac agatgaaagc aaacaataac
     4741 acggtttttt agacccttgt acaaagattc ctacataaca aaatgaggtg gagaaaatga
     4801 aagatttaag gtatagaagt gtctttgata ttattggacc tgtgatgatt ggtccaagta
     4861 gctctcacac tgccggagct gctagaatcg ggaaaatcat acgtagtata tttggcgaac
     4921 agcctgattc tgtagatatt tatctatatg aatcatttgc aaaaacctat cgggggcacg
     4981 gaacagatat tgcattagtt ggcggcctgt tagggatgga acccgatgat gaacgtttag
     5041 ctgattcttt gaaattggca tatgaagccg gtatggaagt cttgtttgtt cctaagagtg
     5101 aaaaagccga acatccaaac tctgtaaaga tgcttctaaa aaaaggaaca cgaaagcttt
     5161 cagtcactgg catttcgatc ggcggtggca atatccagat ttctgaattg aatggattca
     5221 aaatttcttt aagcatgggt actcctacct tgatcgttgt ccaccaagat gttccaggta
     5281 tgattgctaa agtgactagt atactttctg agaccaatac gaatatcggc actatgacag
     5341 tgacacggga atcaaaaggt gaaaatgcca ttatgataat tgaagtagat gatcctcaag
     5401 tagaagaaac ggtaaaaaga ctcaaacagc tgccaaatat cgacagcgta aattatttcg
     5461 attaaggagc taaaaaaatg tttttatcga ttgaagaatt agtagatcaa gcaaaagctt
     5521 atccaagtgt agcagaattg atgattgcag ttgaaatgga aatgagtggc cgttcccgta
     5581 gtcacatcat cgagatcatg gaaaaaaacc tctcagtaat ggaacaatca atcaacgagg
     5641 gaaaagaagg tgttacctcc gtcacaggaa ttaccggtgg tgatgcaaaa aaattagatg
     5701 attatttaaa tgaggcagac tttttaagtg gagaaacaat cttaaaagct gtacgcaatg
     5761 ctgtagctgt taatgaagtc aatgcaaaaa tggggttgat ttgtgctaca ccgactgccg
     5821 gaagcgcggg tgttgttcct ggtgtgctga tggctgtccg agatcggctt gatttgacac
     5881 atgaacagca attggaattc ttatttaccg ctggcgcttt cgggttagtc atcgcaaaca
     5941 acgcttctat cagtggtgca gaagggggat gtcaagcaga agttggttct gcaagtgcaa
     6001 tggcagcagc agctttggtt tgtgcaaaaa atgggactcc tcatcaagca gcacaagcag
     6061 tagccattac attgaaaaat atgatgggac tgatttgcga tcccgttgca ggcttagttg
     6121 aagtcccgtg tgtcaaacgt aatgctttag gctcttctca agcttttatc tctgctgata
     6181 tggcattagc gggtatcgaa agtgtcattc cgccggatga agtcgttgct gcaatgtacc
     6241 aagtcggacg tcaaatgccg tcgattttca aagaaacagc agaaggtggc ttagctgtta
     6301 cgccaactgc taaacgactt gcggaagaga ttttaaataa gagggcgtga taaagctcct
     6361 taatttcgag tattaagaga ttagttatct tcataacaaa aaacgaagag aggactaatt
     6421 gcccttctct tcgtttttta ttaatccatc aatttcgtat tttttacttc atcgatcgtt
     6481 tttgttcctg caagttgcat cgtgatcgac aattctttgt tcaggtgttc aaaaacagat
     6541 gttactcctt ctgccccacc tagattcaac ccataaatca ctggtcggcc aatcgcaact
     6601 aagtcagcac cacttgccag agctttgaag acatgctctc ctcgacggac accagagtcg
     6661 aaaatcactg gtacacgttt gttgactact tcggcaattt ttggcaatac ttcaaaggac
     6721 gcaggacctc catctaattg acgtccacca tgattggata cccagatacc atctgcccct
     6781 gcagagatag cgattactgc atcttctggc gattgtattc cttttacgat aactggaaga
     6841 tgggtgattt ctttgattgt tttgatgtca tctggtgtca agccttgttt tgcagctgca
     6901 taaatttctg cgattccttt tccttcgcca ttaccacttg cactttgttc gctatacgca
     6961 gctaagttag gcattggtaa tggaaattgg aattgattga tgacgtcttc ttcacggtaa
     7021 ccaccgagcg ttgaatctgc cgttaaaatg atagctttag cccctgcttc tactgctttg
     7081 ttcaaaatga actcattgaa tctgtcgtct ttactcatat ataattggaa aaactgcggt
     7141 gcgcctggcg ctgcatcggc tgcgtctttg attgtcgtat ttgcataagt gctgatggaa
     7201 aagattgatc cagcagcagc tactccttta gctgtatcag cttccccttt ttcatgtgcc
     7261 aatccttggg ccgctgatgg cgcttggata atcggtgtat ctaattcaat tccgaaaaca
     7321 gatgtatgca aatcggctga gtcgattccg cgtaatatcc gtggcatgat tttctttgta
     7381 ttaaaagaag tcgtattttc tttcatcgtc cactcatctt cagaaccacc gcgaatatag
     7441 ccaaaagctc ctgcttccat gcgctctttt acacgacctt ctagttaggc aatgtttaca
     7501 atatcgattg gatgttcttc attacttgta tgataagtca tagtagatcc ttctttcatc
     7561 ttcttgatta catataaatc atactaaact tacaaaaagt aagcaaacat ttactctcag
     7621 atacttttat cgctattctt tccaaataaa tcgacttaca agctgatcta cttcttggtt
     7681 ttcatgaagc atactatgag aggcattttc acctgtcact actttttcct ctatttcatt
     7741 tccgcgttgc ttcaacaacg catagaccgc taatgcactg tttaacggta ctgttccatc
     7801 actcaagtct gtttcatcta gttgaccagc aatcaagaaa aatcgagtgg ttataggaat
     7861 attaccgatc atttgctggt aatcttgata gcggttagaa acgacagcag gcccctttgc
     7921 taactcatct gtcagagact gcgcactatc atcgacaaaa tcattaaaag gcgcgccaat
     7981 tgctgttaat gtctgaactt gtggcaatga cgtatcctgt ccatacgttc ctaaatagcg
     8041 tagtgcacta actcctccca tggaatgccc cactatgttg actttatcta tgccgtagtt
     8101 ttctttcaga tacaaaagac aagttttgat ccattctgct tgattccact cgttattttt
     8161 attatcttca aacaatactt ggaccatcgg attgtctgct tttccagaca aatctcctgt
     8221 tgcttgtatt tgtccatctg ttcctactgt taaaaccaat tcttttactg cttgctgatt
     8281 tttttccaaa cgccgcaaca tccctttaaa ggaattttct gtcccgctgt agccgtggaa
     8341 aaaaagtgtt ggaatagtgg ttttttctat cactttactg gattctgccg ttttttcttt
     8401 atcagaaact tcagtagtat ttatcttcgt cgtctggcaa ccacttaacg caaacaaact
     8461 gataaggact aaagctgctg cagttgcacg tttgcataaa tttttgattg gttctgtcat
     8521 acacctcttc ctttccatat agaaaaaaga aagacttgaa aggccaatca tatgatcgac
     8581 atttcaagtc tctttattaa tcgattttat ctacttgatc gaaatcaagt tctgtactgg
     8641 tttcacgtcc aaacatatcg atgttgactt tcaatttttc tttttctccg tcaacttctg
     8701 ttacttgtcc ttctaatcca gcaaatgcgc cttcgatgat tttcacgact tcgccaactt
     8761 ctacttctag atcattttgt cgcaggctca taccgataga acgcaagata tgattgactt
     8821 cttctggaag taatggtgct ggtttgcttc cggctccgtg tgaaccaacg aatcctgtca
     8881 caccaggtgt gttgcggaca acataccatg aagcgtctgt catgatcatt tcaacaagta
     8941 cgtatcctgg gaatgtttta tgaacgattt ctttttcttt cccatttttg acttcagttt
     9001 ctttttcttc aggaacaacg acacggaaaa taaagtcggc cattttcata ctttgcgcac
     9061 gagattcgat atttgctttt actttgtttt catatcctga atatgtatgc aagacatacc
     9121 agtttttttc aaaagattcc attgaaggct cctcatttca ttgtaaaata aaaaaacctc
     9181 agtacacccg aagtttttct ttcgcttcat tatagcacta aaagtacgtt gtggctagcg
     9241 agttatttta aaatccagcc aaataagctt tggatggctg tatccattac gtaaaacatc
     9301 aatccgaaaa taatagaagt ttcgatgact actaacgtat ctttacggag ttgttttctg
     9361 cttggccaag ttacttgttt gatttcatct tttacgcttt ttagaaattt catgagacaa
     9421 cctcccttgc tactgtttat ttcgtttctt tatgtaatgt atattgatta caatatttac
     9481 aaaacttatt gatttccaaa cgttcgccgc tttttccttc actgactgat tttgtgtagt
     9541 tgcgagaccc acaaacggaa caagcgagtg ctgctttttt ctttgccatt tacttctgcc
     9601 cccttgctga gaatcagact tatacttcat aacagtatca cgtaactttt tacttgtcaa
     9661 tttgtgaaat aaactatcta ttgttttgga taaaattatg atatgattaa tttgaaatta
     9721 agctaaaatg agacaattgg aggtatagcg atgctattaa aaacacttgt atataagaaa
     9781 aaagatctga caaccgttac agagactagt acattagaag aagcattaaa aattttagaa
     9841 acttccggat accgttgtgt gccgatctta gattcttcag gtaatatttt ccgtggaaac
     9901 atttacaaaa tgcatatcta tcgtcataaa gcaaatggcg gtgatatgac gcttcctgtc
     9961 actcatcttt tgaaaaacgc tacaaagttc atttacctgg atacttcttt cttcaaagta
    10021 ttctttacga tcaaagagct tccttatatt gctgtccttg acagtgaaaa tcatttttat
    10081 ggtattttga cacatagtac gttgcttaat atgctctctc aatcttggag cgtagaacaa
    10141 ggaagctatg tactgacaat tgcttccaca ggaaagcaag gagatttggc tgctattgca
    10201 aaaatcattt caaaacacag cagcattgcc agctgtatta ctcttgatat cgaaaaagac
    10261 gaatacattc gacgtacatt gatcacgcta ccggctaaca ctgaagcgaa agtatgtgaa
    10321 acgatcgtca accacttaga gaaaaagaat tataaagtgg tagaaattga aaatttgcaa
    10381 aaccaagaag cataatcaaa aagcgaaaaa agaaaacagc taatctgctt tcttttttcg
    10441 ctttttataa ttagacacgc ttttcaaaat caagcgcgcg atctaaataa tacatcaatg
    10501 gtgctgaaac agccatgacg ataaactcac ttaatgcaag cgtgccatag gttgtccaaa
    10561 atgcttggcc acctgttgga actaacatat aagcaatcag tcccatgctg atggtaaaga
    10621 agatcgtgtt caatactaaa cgcatcttta catttttcac tttgttttgc aataaagctg
    10681 tcaggcctaa agaaagcaat gtttggccgc caccaaaaac cacatccatg ataccaaaac
    10741 caaagaaggc attatagacg atgaccccgc ctaaaactcc ccaaagcaat ttacggttaa
    10801 agacaactaa atgattcaaa ctttctgaaa tacgaaactg gatcggccct gaggatacag
    10861 gcgcaactaa aatagttaac gctagataaa gagccatgat gatgccattt acaacgatta
    10921 cggataaccg ttgtctgctt ttcgtttttt gcattttctc tcctcttttc tcctagtttt
    10981 tttaacgcgg gatggttgat gaaccgcggt tatgtgaaac aaacaataat tataacagac
    11041 ttttcattta tttcaatccg tcttatctgc ttttaaaaaa gcaaaagctt aaacaatgta
    11101 aacgtttgct aaaaatcgtg ggatatggta taaagtaagt gtaaggggtc ataagaattc
    11161 ccagtaaagc agacgaagta ggatctgcaa gaacagaatt gttgtgaaac ttaaataaat
    11221 aaaaaaggat gtgggaattt gagcaacctc ttactagaga acggtctagc aagcagctga
    11281 agatctaagt ggacatgccg aaccttggaa cttctcctta cgtaagtaat ggatcatgcg
    11341 cttgctaggc ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg
    11401 ctataataac caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat
    11461 tcaaaaaata gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata
    11521 tcttgtttta ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat
    11581 ccatcggcag gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa
    11641 aataagcata ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt
    11701 gctgaaactt tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc
    11761 gatactttcc cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat
    11821 actttctatc agatggaagt agaattccca gttgcttata ttccagcagg ttctggaaat
    11881 gattttgctc gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta
    11941 gcagctcaat caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa
    12001 aaaggaatag ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca
    12061 aatcattctt ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta
    12121 ttctctattc tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga
    12181 ggaaaacaat taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt
    12241 ggcggaggaa tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc
    12301 gtggtcgaac gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa
    12361 aaacaattga aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca
    12421 acaacaccgc aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc
    12481 acaataacca caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta
    12541 catctggaac accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt
    12601 tttttactat gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta
    12661 cccaaaataa attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg
    12721 aaccaaaaag attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta
    12781 ttttgaacaa accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag
    12841 tattctgctg gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg
    12901 atcccaccgc tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg
    12961 atcggcaata aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag
    13021 gtgtggatca ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa
    13081 ctaatcaaac taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg
    13141 tttcgtttac tgatctcttt gcgattaaac gctagattga tgacgctgaa accgctaaaa
    13201 atggatagaa acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc
    13261 atccgctgac tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt
    13321 gtctgttcca tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc
    13381 aaaaaggtgt tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt
    13441 atcttgatcg tcgccatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt
    13501 aagataatgt ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca
    13561 tccaatgtaa cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc
    13621 gactcttctt cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca
    13681 atattttgcg caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc
    13741 gatttatttg ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct
    13801 ttccatccaa gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt
    13861 ggtataaaaa ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa
    13921 gttgacgaga tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg
    13981 ttccgacccc atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct
    14041 atccttttgc accagattca tttttggtat caaattacca accaatgtac ctaacaaaat
    14101 cgcacacaac gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc
    14161 tacttgatag ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt
    14221 aaagcttgct gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa
    14281 gcgaatacca tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat
    14341 cgtcccgtag agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat
    14401 attacgacct gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg
    14461 cgcgagatca acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa
    14521 aaattgatcc atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag
    14581 cgaaacagat gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc
    14641 attcgcttct acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac
    14701 ttgttctaag actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat
    14761 tccagtatta atcgtttcaa gattgccacc ttgatcaatc tcgccaaagg ccgccataaa
    14821 catcaatcct aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag
    14881 cagtattttt gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc
    14941 tcaaatcctt gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta
    15001 tttttccgta actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat
    15061 ttagttcagt agttgttact tggagctgac cttttttata agcgattcca tcagaagcta
    15121 ttgttcgctg aatcgctgac aacacatttt ctgggagtaa tgggatgtcg atcgtcaaac
    15181 gatccgccgt ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc
    15241 cttgatccat gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg
    15301 tatagacaat ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc
    15361 gactttgggg gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg
    15421 caatcccaca tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa
    15481 acgaaacata tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt
    15541 tctctttttc ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt
    15601 cgtcaaagac cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt
    15661 caggagtcat tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa
    15721 gcatacagtt gatggcagtc gatttcccac tgccgtttgg acctaacaga cctaagactt
    15781 ctccttcttg tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga
    15841 ctaatttatc aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg
    15901 actataataa agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt
    15961 gtcacaatga aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta
    16021 ctggttatct cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat
    16081 ttattgatcg ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg
    16141 attttccaag ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg
    16201 ccagcgacga tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta
    16261 ggttttttgt tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta
    16321 attttgctgt ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag
    16381 aaaaagtaca ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa
    16441 aataaagcat tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg
    16501 aaccgaattg cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta
    16561 caaattggtg cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat
    16621 ttaagtgcca ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat
    16681 gagacatcga tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct
    16741 gttacgattg aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta
    16801 atggtcatca aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt
    16861 ttacattttc gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc
    16921 ccacaaaaaa attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa
    16981 caaaagggac aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta
    17041 ccaagggagg gacaccaatg ataacagtag tcattattga tgatgatcca tttgtgacga
    17101 aatcgttaca aaccatttta gaaagcacga aagagatccg tgtgttaggc attggtcatt
    17161 gtgccaagga tgcgctagtc ttatacgaaa cccatcgtcc cgatgttttg ctgacggaca
    17221 tccgcatgcc taaacaaacg ggcatcgatg ctgccaaaga aattttggct aaatttccca
    17281 aagccatcct tttgcttttg acgacattca aagatgaaga atacatccgc gaagcatttt
    17341 ccatcggtgt caaagggtat ttaatcaaac agaacttgca agcgattatt ccttctgtca
    17401 aatccgctta taatggacag gccgtatttg gtaatgaaat catcgagact ttcactcaaa
    17461 tgatgaagaa taaaccgacg attgatagtc atgcttatgc ttcttttagt gaacgtgagc
    17521 ttgcaatcat caaagaagta gctgccggga aaaacaataa agaaattgca gatgccttgt
    17581 acttgagtga cggcactgtt cgcaattaca tcagccaatt actagaaaag ctagatttac
    17641 gggatcgcac gcaattggct atctattttt atcagcattt gcaataagtc ttatctaaca
    17701 caaaaaaacc tgaatgatgc tccttcgcat cattcaggtt tttttcacat cttctattca
    17761 attgtcccgc aaaccatttc ctcacgattg aaagaatcaa ggattcgcag ggctgccagg
    17821 attcgttgga ttgttcggcg tgttaggcgg aaaaataggc gccttgtcta acgttttttc
    17881 tagttttgat tcttcacgat cgtctcgttc tacatcagga ctttcattca atttgaattc
    17941 tttttccatc tcatctaact ttttaaagtc attgccagat tcttttgcta atttcgctaa
    18001 tttatcttcg gtttctttag ccataaagta acgcccccct tttgatttca gcttagcata
    18061 tcacactgaa aaaacaaaag aaaacgctaa ccaacgatca tttttagcta tttctcatct
    18121 ttaaaatcaa gcattttttg ccggtataaa atcgtaggga gaactgtttt ccataccaat
    18181 catcggatct actaactggt tatcgatcac ttctgctgta agaacgaaat ctttagaaac
    18241 agcaggttct acctcttctt tcttttcttc tccaacaaat gaagaaaaca gatctggttc
    18301 cactgtttcc attacttggt ttttcgtttc attcgtccca ctgtcatctt ctacaggtag
    18361 cttttctttt acaacccgtg gctcttttgt atagttccca tcttcaaatg gatcatttcc
    18421 gaccaaagaa tcttcataag ctgctagttt ggtccggaga gtgatattca ttttatcatt
    18481 atccatgatc cttgatttca acgtagtcat ccggcttgct gattcattcg ctacacaagt
    18541 gacataggct tgctcttccc ctaacaaaat caacagttcc ttactgcgag tcactgccgt
    18601 gtagagcaaa ttacgctgaa gcatccgctg atattgatgg accatgggca aaataaccat
    18661 cttgaattca ctgccttgtg atttatggat tgagcaacaa taagaaagag tgattttatt
    18721 ccattcgttt cttttataag tgacctcatt tgcatcaaac tggataacta attcatccac
    18781 tttatcttca gaatcttttg ccaagatgat acccgtgatt tctcccatat ctccattgaa
    18841 tacattcaat tcgggagtat tgactaattg gaggactttg tctcctatcc gataaacggt
    18901 gtcgttccaa tgtacttcct tttttccagg tttccctgga ttgaatatct cctgcatcat
    18961 tttatttaac gcatcgatcc ctgcaggtcc ccgatacatt ggtgctaata cttggatatc
    19021 ttgtgcacgg aatcccttat ttttcgcttt ttccacaatt ttagagatca agggttcaat
    19081 ttgataagca tcacttcgga aataggaacg atctttttga ttctttgtga aatcttttgg
    19141 cagacgtcct tctttgatct catgggcaag aggaataata ctagaaccat caccttgccg
    19201 ataaatctga ttgagttcca ttttgggaat ttgttcgatt tccaaaagat catggagtac
    19261 ttgaccagga ccgacagagg gaagctgatc tttgtctcct actaagataa cttgcatatt
    19321 cgtcggaatc gctttgaata atgtgttagc cagccatgta tcgaccatag acatctcatc
    19381 aacaatcaaa agtccgcctt ctaattcttt cgtactgact gaaggtgttt tttcccgtcc
    19441 attcagcccc agaagacgat ggatcgtact ggcaggcaga cctgtcgttt cgttcattcg
    19501 tttagctgct cggccagttg gtgctgcaag tagaatagga aaaatttctt gggtatattt
    19561 tgaaggatcc aattccagtc cgttcaactc tgcaaaaaga ttgacgattc cgttgatcac
    19621 agtagttttc cccgtacctg gtcctcctgt taaaataaat agaggggaac ggattgcttc
    19681 agcgatagct tgttcttgcg aaggtccata ctgtatgccg aatatttttt cgatacgccg
    19741 aatattcttc tgcacttctt tttcaggata atggatttct tttttacgac tgagaaggcg
    19801 ctggatcgaa ttaccgatcc cccattcaga aaagtacaaa ctgttttcgt aaagattagt
    19861 ctcttcttgt tgtatctttc cttcttcaac aagttggata attacagtag caacctgatc
    19921 aggctggatt tcaattgggc gacttgtttc taaaatacgg atcgtttgct gaagcaatgt
    19981 ctccgccggt acgtatgtat ctcctgtttg aactgcatgc tgaaaaatct gatgcaagat
    20041 agctgctcga attcttctcg gtgaatctgc tgcaataccg atttgttcgg ctagattatc
    20101 tgcacgtttg aacccgattc cttctatgtc ttcgactagc tggtacggat tttcttcgat
    20161 gatatccaaa gactcgttct tataggcctg gtagatactg aaagctaact gactaccgaa
    20221 cccgtaacga ttcagtccca tgatcacttg atccatcccg tggtttagcc gaatcgtctc
    20281 agcaagcatt tctctttttg gcttcgtcaa accggagatt tgttttaata ccgaaggatc
    20341 agcaatgatt ttttcgatag catcttctcc cagcaattct acaatttttt ctgctgtttt
    20401 cttcccgatt cctgggaatt tttcgctgga aagatacgct acgatcccat ttgcagttgt
    20461 tggcttttct tgctcatatc tttcgagttt aagctgcctt ccgtatttag gatgatccac
    20521 taattctcca taaaaacgat aagtctcatt ttcttgaata tcgccgaaac ttccggtgac
    20581 tacaatctct ttttcacggt aatcagctgt ggtttcactg atgtgtacca aaagcacttt
    20641 gtaaaaatta ctaggatttt gaaaaaaaat cgcggcaact gtaccaacga aataaggcat
    20701 ttcttctggc tgcatcggaa gccgcctcct tcttctatag taaaggttct ggtgctgttt
    20761 cagttcctaa aaaatctgtt tggttccata ctttcagttc atatggcaat aatctgcaag
    20821 gctcttcagt ctctaaaatc gtcaaactac tattgaacaa tccacccatt tcacgcaact
    20881 cacttagctc ttttcctgtc atccattgaa tggctgcagt taaagaagct ccatgtccta
    20941 cgaataaaag tgggccatct ttatgtcggg caaccgcatc tgctacaaca gtttcgatac
    21001 gtgtgattgc cgattcaatc gtttctccgt gaaaaggaga aggatcatac agatctaaat
    21061 gattacgcaa attcggcaga ttatccggat atttctggta catttcatcg atcgactgac
    21121 cttctaaagt acccagccct agttctctta gcttatctgt ataaaaaatc tctaccggac
    21181 gagcaagctc tttgttgata ccttctgctg tatcacgtgc tcgctttgct gtactggaat
    21241 aaattgcttt aaaaggaaca tattttacct ttttcccaaa tgctttgatt tcttcgtaac
    21301 tttgtggcaa aagcggagaa tcgccattgc tcccttgaaa acgtctttcc tgattccatt
    21361 gtgtcttccc atgtcgggta aaatatagtt ccatacgcag caaactcctg tctttctttt
    21421 attttactct ataataaact gtctaatcca gcttgtcatt ttcatagtga tgcgtcaatt
    21481 ctaaattagg gaatccttgc tggcgaagtg cttcatacac tatcattgca gctgtattcg
    21541 ataaattcaa tgagcggaca tgctcatcat tcatagggat gcgtaaacac ttttcttcgt
    21601 tttcacgcat aaatgtttct ggcaaaccgg ttgtttcttt tccaaataaa aagaagtgct
    21661 cttctccatc agcaaaattt tcgtcactat atactttatg ggcaaatttt gagatcaaat
    21721 gtagtttacg attacctaaa aatgttaaaa aagcttctaa attactgtgg taagtaatat
    21781 ttacatcatt ccaataatcc aaccctgccc gttttagatg tttgtcatca gttgaaaaac
    21841 ctagtggctc gattaaatga agcggagtat tcgtggctgc acacgtacgg gcaatatttc
    21901 cagtgtttgc agggattaat ggttcaaata aaacgatatg attcatcagg atcattcctc
    21961 tcatatttat gttcgtttct attttctgac aatttgattt ttgcataaaa aaaaacgtat
    22021 caactcggtg tcagtcactg cgagtcgtta cgttagtgaa gctcttctca ctaactttta
    22081 tcagaacagg aacctgataa aaaccaatga aaaaacaact tgttgctaat ataacaccct
    22141 caactttttt ttgcaacctc tactcattaa aaactgctag aaaaacgttt tctcttagtt
    22201 ccttttaata attctatgtc aattgtaatc ttcttcaaag gattcttata taagtctgct
    22261 ttgattcgct cttctacctg ccattctaaa ggtgacatgg ccaaaagatc tttttgattt
    22321 tcctctggta tctcaaattc ataggttaca cgctgacgtt cagttaattt cattgcttca
    22381 gcaaacttgg ctactacacg ttcattggaa taactctgtt tttcaggttg attcggataa
    22441 aaagcctgac gtagttcctt taaataattt tcttgtggca ccaccttcaa cacttctcca
    22501 tcttctgaga gtacacgttg gaattcttgg taatgagaag gcgaaaagat atttaaaacc
    22561 gcgttgaatg tttgatcagc aaacggcaaa ttggtcaaat cagctacaca ccaaaatgct
    22621 tcggcagatt gttctgtagc tgcgtagact ccttcttttg aaatatcaaa tccaacagca
    22681 ttttgaatct ttttcaattt tgaaagttca ttcaagaagc taccttctcc gcagccaaca
    22741 tctaatagcg agacttcttc aggtaaatgc tgcgcaatag tctcaataac gggctgatac
    22801 atgccagatt ggatcattct acgccttgga acgaacattc cttgatcgta ttctgtttta
    22861 accgcatggg ataaaaaata aagtgttcct tttttggaaa ggtcaaaacg gtgattattt
    22921 ttgcatatca agccattatc agactttttt acttcttctt ggcaaaccgg acagcggaac
    22981 agctgatgat tttctgccaa aaactggcgt cctcggtcaa ttttttttaa catagttccc
    23041 cctcatttct gttttatctt accgttagat gctcactttg gcaactgcta aaaatatgat
    23101 acaatgccta gaagaaagtg aaagataaag gagaagatta gatgatcaaa gaattttgcg
    23161 ctgaaaacta cacatctatt cctctagcaa ttgctagagg agccgatcgg atcgaattgt
    23221 gtgacaactt agcggtcggt ggcacaaccc cgagtactgg tgtgatcgaa gaaacgttaa
    23281 gttatgctgg ggaaaaagat atccccgtaa tgacgattat tcgtcctaga gggggcgact
    23341 tcgtctataa cgatatcgaa ttgaaaatca tgcatactga tttgattgaa gcaaagaaat
    23401 tagggacgga tggcgtagta tttggttgtc ttactccttc aggctggcta gacgaagagg
    23461 ccttagaact attgatcgaa acagcagaag ggttgcagat caccttccat atggcttttg
    23521 acagtattcc tgaagatcgg caattcgaag caatcgattg gctggtagaa catggtgttg
    23581 accgtatctt gactcatggc ggtcctgctg acaaaactat tgtagaaaat ttcccacggc
    23641 ttaaagaatt gattgcctat acagatggcc gcttaatcat tttgcctggt ggtggtgtca
    23701 ctgcagagaa tgcagcacat gtagctaaag aattgaacgt aagcgaagta cacggaacca
    23761 aaatcgtgga tcttcagtta taatcttata aacaaaaaaa catttgcaac aggcataatg
    23821 cttattgcaa atgtttttgt ttttttacat aaaatagccc ataaataaag aagcaatatt
    23881 gaaataaatc agtacactcg tcaaatcgct caaagtcgtg ataaagggac cgcttgctac
    23941 tgctggatca aatcctagac gatccattag catcgggatt aaactacctg caagattcgc
    24001 cactgtgatt gcaaatagca tagccatccc tatgacaaac cccaagataa aattatgttt
    24061 ccaaaaacct acgattagaa aaatcgtgat ccccgtaaca gctcctgtga caacgccggt
    24121 caagacttca gccaaaacaa gtcgaacaaa tccatgatct ttctcatcag aaatcgcaag
    24181 tcgacgaaca gccacagcta gcgactgggt tccagcatta ccggcagttc ctgtaatcag
    24241 cgaaatgaag actgctaaaa tactcgcttc acttaccaag tcttcatagt gactgattaa
    24301 agaagcggtc gacataccta aaaacaacag agtgatcagc caaggcaaac gtcgagacgc
    24361 tgcctttact ggattttcat taatttcttc cacattgacc ccggcaagtc ctgaataatc
    24421 gctagcagct tcatcatcaa taacgtcgat gatatcatcg actgtgacga ttcctaacaa
    24481 atgatcatca taatcggtaa caggaagagc taagaagtca taatctctaa atgtttgtgc
    24541 cacatcttct tggtcgtcgc ctacatgaac tgaaagcact cgttcgctca tcagatcaga
    24601 aatcattgcg tcgtcatcat tcacgattag gtcgcgcaga gaaataaccc ctactagctg
    24661 accttcttga ttaacgacat agatgtaata gattgtttca gctacatctg cttcgttctt
    24721 cagcacgtac atcgcagagc gaacagtttg attggctacg atcgaaacaa attcagttgt
    24781 catgatcgcg ccagccgttt catcctcgta atggagaagt tccttgattt cactggcatc
    24841 gtctgccgac atcaaactta aatatttagc aatttgcttt ttatccagcg tattaagcaa
    24901 gtcaacagca ttatctgtat acatctcaga aagcatatca gctgcatagc taggacgcat
    24961 ttcatctagg tattctttca tatgttcgtt gtcttcttca atcacatcga acatatccgc
    25021 taattcttta ggcgacagat aggaatagat cagctgcctg ttctcttctg taagagattg
    25081 gtagaattgc ccctgctcat agatatgcat ctctaaaaaa ctgtttctga atgcctgaat
    25141 attattttcc cttaaatctt gagtcaactg ggcaaatctt tcctctaatt cttgattttc
    25201 atccaaacca atctcacctc gccttattct tcaaaccgtc tcacaactgc ctccatgtct
    25261 gcggctaaag gctgcttgaa ctccagcaac tcttctgtaa atggatggta aaaacgcaga
    25321 tcataacaat gaagggcttg tctttttatt cccagatcca ttcgcccgcc atacatatca
    25381 tcaccgagca gggcacagcc aattgcggaa aaatgaactc ttatttgatg tgtccttcct
    25441 gtatgcagct ggatatcaac taacgcgatt tctgttagtc gcttctctat ccagtactca
    25501 gtctgtgccg aacgtccttc atcagagacc attcgcttca atagcgaaga ataatctcgg
    25561 gcgatcggca aatcgatatg tccatgtgcc gataaatctg aaagccttcc actgactaag
    25621 gcctgatatt ttttcacaaa cttcttttca cgaagttgca tatctaattt tgcgtgcgca
    25681 aatccatgct ttgcaaaaag catcaagcca gatgtatccc gatctagtcg cgtcaccaca
    25741 tggattactt ggttttcgta accttgtttt ttataataag cctttacacg attagccatt
    25801 gtcccatttg gatggtattg ggcaggaata gacgaaacgc ctgctggttt atttactacc
    25861 agaacgtgtt catcttcata cacgatatcg atcggtgttt catccaaaag tacggtttca
    25921 tgttctcctt cagcaggaat cacaatggtt accttatcat ccttagctag agaaaacaag
    25981 acattttcta cttgatcatt aactttgatt tgaccgcctt gaaattttat tttcgctaac
    26041 agaccctttg agatcccttt ttcttttaaa aaatatttta cttgctgaga atgatctttc
    26101 tcataatccc atgtaaactg catatcaatc ctcactaata aaggcatctt tcacacgatg
    26161 ccaaaaatgc atatgtcgat aagaagcaaa atggatccgt tcttctgcta ttcgataata
    26221 aattgagcgg atatttgctt ttgcgacatt caattgatca accgttacaa gataatcttc
    26281 tgtattttcc aattttattt ctagccattc atcatgggca atcacgatcg gagaacccaa
    26341 agtacgaaac actcgattat tcagtgaagc aatctctgcc aactgaaagg cattgatact
    26401 aggatggatc acagcaccgc cgacactttt attatatgct gtcgaaccag taggcgtaga
    26461 aatcgtcaat ccatctcctc taaaactttc aaacagctcg tttttgatgt atacatcggc
    26521 taccatcgta cgattggccc gtttaatcgt tgattcattc agtgctaaaa aatgctggtc
    26581 cggtgtttca tccaaataac tgatccgaac atccagcaag ggataactaa cactttgttc
    26641 ccggttcgtt cgtaagctgt ctactagttc ttccagctcg taatcccgcc aatccgtgta
    26701 aaaccctaaa tgacctgtat gcacgcccaa gaaacgcaca tcattcagac aatgactgta
    26761 gtgatggaac gccgacaata atgtgccgtc tccgccgact gagatgacca attctggctc
    26821 atgatcatct cgttgaatcc ctgcttgttc taaaagtgcg ttcaaacgtt ctgtcacttc
    26881 tatagtcttt gcttctttat tatgaacgat cgctactttc atcccctgcc tcctctcttt
    26941 cgctttcttt cttcaaaagc gttcgatagt agacatcatc tgattttcct cttccatggg
    27001 agaataaccg ctgtgcttct tggatttctt cacggatact ggacatctct tcatccaact
    27061 gataggcagc ttctgccgca cgctgaagtc gttcactcat ttcttctgga aaaacgcctt
    27121 gatatttata attcagcgaa tgctcaatcg ttgcccagaa attcatcgca agagtccgaa
    27181 tctggatttc cgccaaaatt ttcttctcac cgctgatcag ctgtacagga tactcgatca
    27241 ccagatgata agaacggtag ccacttgctt ttttatttgt gatgtaatct cgttcttgga
    27301 gaactttcat gtcttttctt ttacggatga tctcaacaac ttgatggata tcttctacaa
    27361 actgacacat gatccttaac ccggcaatat cagacatttc ttcttctaaa cgtcccattg
    27421 gaatatgccg taattgtgat tttgttacaa tactatcgac tggcttgact ctcccagtga
    27481 caaattcaat cgggacatgt cgattttgtt cacggaactg tttgcggatc ccccgcagtt
    27541 tcactttcaa ttctgataca gtttgttcat atggtgctaa aaatgcttcc caatctcgtt
    27601 ccatagctga tacctctact tcattaacat tcattgttta ttctaccata tatgcaaagt
    27661 tttttcgtac tcttgattta tgcattgacc aaaaaaagaa aattaggcaa aatagacaaa
    27721 aaggagtcga tcaaatgaca caaatgcttg aaatcgaata taaatctatg ctgacaaagc
    27781 aagagtacga gatattcatc gctcactatc aattaacaga taaagatttc cgtgtacaga
    27841 ctaatattta tttcgatacc gttgatgaac agctgaagaa acaaaattgt ggcctacgga
    27901 tccgtttcgt tggtcatcaa gctgaatata cattaaaaac acctgctgaa aaagggcgtc
    27961 tcgaaacaac ggataccttt ataacagaag aagcagaagc atttatcttc gaaaaacgtc
    28021 tgcctcgttc aggcgcagtt tttcaaaaac tttctgattt gaatatcgat cctgcttcat
    28081 taatccaaac cggaaagctt acaacaaaac gagctgaatt ccctattgaa gaaggacttt
    28141 tagctattga tgaaagctgg ggagacaatc tacacgattt tgaactggaa ctagaggtag
    28201 gggatgcatc tgtgggaaaa attgctttta taaatttttt aaaacgtttt tctttacctt
    28261 atcgtcctgc taagaacaag atccaacgta tgcttgaagc taaaaattag aaacctttca
    28321 ttttcacaag gcacttgagt tcattttttt acttttttct gttaagttat aggatgtgaa
    28381 agaatctagt cactagttgt atagaatcta ttttggggga gattcatatg atcgaaatct
    28441 atttatttgt taatccttta ggggaatact gtttcgaaat ggaacaacag ttattacaat
    28501 ttatcgaaga agagtacggg acaccatcaa aagaaaagat gcaatttcgc tttcttcctt
    28561 tggtcaattt gcagacaatt ggggatgtca tgcaacaaaa aggaatttct cagaacaatc
    28621 ttgaggaacg taatcactta ttctcaatga cttattctgc agcattggac tgcaaagcgg
    28681 cgcagtttca aggaaagaaa aaaggccgcc gttttttgat caaattgcaa gaagcagtcg
    28741 gctgtaatga cataccatat tctcaagaac ttgctgaatc catatttgaa gaaatcggcg
    28801 gcgatttgaa tatgtttaaa gaagatcgtc agtctgactt cgttaaagaa gtattctttt
    28861 ctgatcaaaa aattgctcgg gaaatgggca tcacaaaaca cccttctgca gtcgtttaca
    28921 attatgcctg cgaccgtgat tttggtgttt tagtagaagt aaaaggtaca agtagccttt
    28981 ggagaatcac agagctgtgt aaaacaacag ataactcata tcaagttttt aatggtgaac
    29041 atttacatac aaatgattct cagttccatt caagaactag ccatttacac ttgctttcta
    29101 attaaaaaag gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa taatttggac
    29161 agaacagaaa gaagaaaacc tctttctgtt ctgtttattt ggttaaaaat gttttgc
//
LOCUS       DBGZHO010000029        28862 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.029, whole genome shotgun sequence.
ACCESSION   DBGZHO010000029 DBGZHO010000000
VERSION     DBGZHO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.029"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            4..243
                     /locus_tag="ACN3HL_001508"
     CDS             4..243
                     /locus_tag="ACN3HL_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006390.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..519
                     /locus_tag="ACN3HL_001509"
     CDS             310..519
                     /locus_tag="ACN3HL_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006391.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            579..1250
                     /locus_tag="ACN3HL_001510"
     CDS             579..1250
                     /locus_tag="ACN3HL_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HHC8006392.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1303..3279
                     /locus_tag="ACN3HL_001511"
     CDS             1303..3279
                     /locus_tag="ACN3HL_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HHC8006393.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3292..4047
                     /locus_tag="ACN3HL_001512"
     CDS             3292..4047
                     /locus_tag="ACN3HL_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HHC8006394.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4044..4868
                     /locus_tag="ACN3HL_001513"
     CDS             4044..4868
                     /locus_tag="ACN3HL_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HHC8006395.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4878..5126
                     /locus_tag="ACN3HL_001514"
     CDS             4878..5126
                     /locus_tag="ACN3HL_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006396.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5169..7268
                     /locus_tag="ACN3HL_001515"
     CDS             5169..7268
                     /locus_tag="ACN3HL_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HHC8006397.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7306..9363)
                     /locus_tag="ACN3HL_001516"
     CDS             complement(7306..9363)
                     /locus_tag="ACN3HL_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HHC8006398.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9477..9689)
                     /locus_tag="ACN3HL_001517"
     CDS             complement(9477..9689)
                     /locus_tag="ACN3HL_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006399.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9876..10343
                     /locus_tag="ACN3HL_001518"
     CDS             9876..10343
                     /locus_tag="ACN3HL_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006400.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10340..10582
                     /locus_tag="ACN3HL_001519"
     CDS             10340..10582
                     /locus_tag="ACN3HL_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HHC8006401.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10600..10902
                     /locus_tag="ACN3HL_001520"
     CDS             10600..10902
                     /locus_tag="ACN3HL_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006402.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10974..13028
                     /locus_tag="ACN3HL_001521"
     CDS             10974..13028
                     /locus_tag="ACN3HL_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006403.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            13028..15640
                     /locus_tag="ACN3HL_001522"
     CDS             13028..15640
                     /locus_tag="ACN3HL_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HHC8006404.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            15637..18015
                     /locus_tag="ACN3HL_001523"
     CDS             15637..18015
                     /locus_tag="ACN3HL_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HHC8006405.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            18076..18618
                     /locus_tag="ACN3HL_001524"
     CDS             18076..18618
                     /locus_tag="ACN3HL_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006406.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            18696..19028
                     /locus_tag="ACN3HL_001525"
     CDS             18696..19028
                     /locus_tag="ACN3HL_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006407.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19029..19622
                     /locus_tag="ACN3HL_001526"
     CDS             19029..19622
                     /locus_tag="ACN3HL_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006408.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19644..21338
                     /locus_tag="ACN3HL_001527"
     CDS             19644..21338
                     /locus_tag="ACN3HL_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HHC8006409.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            22026..23903
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001528"
     CDS             22026..23903
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001528"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HHC8006410.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            24034..24411
                     /locus_tag="ACN3HL_001529"
                     /pseudo
     CDS             24034..24411
                     /locus_tag="ACN3HL_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24411..25616
                     /locus_tag="ACN3HL_001530"
     CDS             24411..25616
                     /locus_tag="ACN3HL_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HHC8006411.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25632..26276
                     /locus_tag="ACN3HL_001531"
     CDS             25632..26276
                     /locus_tag="ACN3HL_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006412.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            26287..27093
                     /locus_tag="ACN3HL_001532"
     CDS             26287..27093
                     /locus_tag="ACN3HL_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006413.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            27115..27345
                     /locus_tag="ACN3HL_001533"
     CDS             27115..27345
                     /locus_tag="ACN3HL_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006414.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            27891..28166
                     /locus_tag="ACN3HL_001534"
     CDS             27891..28166
                     /locus_tag="ACN3HL_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006415.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            28208..28630
                     /locus_tag="ACN3HL_001535"
     CDS             28208..28630
                     /locus_tag="ACN3HL_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006416.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28649..>28862
                     /locus_tag="ACN3HL_001536"
     CDS             28649..>28862
                     /locus_tag="ACN3HL_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006417.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKT"
BASE COUNT        10493 a         4472 c         5860 g         8037 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgagacgaac ttatagaatt catttttaaa actttttcta tggaaatgag
      541 aaaaagtttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
      601 ttttaggagt cactttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
      661 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
      721 cacatgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
      781 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gtatttgcac
      841 aaattcagat tcctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
      901 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggc aaaggaaact
      961 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcaaaagt
     1021 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     1081 cgcgtaaatt tatcgtacct gggtacttta aattaatcga tggcgttcct gaagagaact
     1141 ctttcttgtc tttgccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     1201 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     1261 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     1321 gtaaaaaaag ctggaatgct tgttggaatg ttaggaatca ttgcaggctg ctttcagggg
     1381 tatcaagtac atgcagaaga tgtcacgcaa aaaacaccac cagagaaggt caatatcacg
     1441 gttcataaat taatgtacga tcaaggaacg caattgaatg ttgatattga cgggatcaaa
     1501 aacgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     1561 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gagagaagat
     1621 tctgatctaa ccaacgcgaa agtggacgag attgtacaag atgtagaaga caagggatct
     1681 aacagtgagt acgtcaagaa tgcaaccaac aaaattactt cagctgtaga tgaaaatggt
     1741 gagatcactt ttactgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     1801 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     1861 gcgccaatga cagataaaac aggatcagga tttttaaaaa atattcattt gtatcctaag
     1921 aacattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cgcagaccaa
     1981 agcaaacaaa cccttttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     2041 ggaacaaaat tgggtgatct tgtatcggat gatcaaggaa agctgactgc gactgatttg
     2101 acgttaggaa aatactattt tgtggaagtt ccttcggaag ttgtagtggg atcagatcaa
     2161 gaaccaacag cagatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     2221 ttaacctttg aaattacgaa tgatggcgtg acaagtgact taaaagcttc atacgtaaac
     2281 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     2341 caaattggtg acgcagtaaa ttatcaagga acgattcata ttccaacaga cattgcaggt
     2401 ggcgcagacg gtatcacagt aaacggtgtg aaaagcgaaa cttctcctta cagtgtattt
     2461 aaatggggag atacagcagg taaaggactt tcttatgttg ctgaaaaagc agatattaaa
     2521 gtaacaaata atgatggttc agtcgtatta aaagaaaata ctgactataa aatcgaaaat
     2581 tctgatagtg gttttgtgat cgattttatc gtaaataatg gacaagtaag tgatacagtt
     2641 gcgaatttac atggtcaaga tctaaaaatg acttataaca tgtttgtgaa tgatagtgct
     2701 gaaatcgcaa atccattaac aaatagcgtg gatttcgttt ataacaataa tccatttaat
     2761 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggcgc aaaattctta
     2821 aaagtcgata gcggcctatt tggaacaggt atcaaagcaa caccgcttga aggcgcagaa
     2881 tttgcagcta agaatgcaga aggtaagtac tacggtggac ttactgatac agataaagat
     2941 ggtgtcaaag aagcagtttg ggtagacgat gtagcaaatg cagcaatcct aaaatcagat
     3001 aaagagggtc attttgaaat cactggttta actgaaggag attactcact ggaagaaaca
     3061 aaagctcctg aaaactatca aaaattaaca aaagagatct ctttcaaagt agacaaagat
     3121 tcatacaaag aagaaaaccg aatcacgatc aaaaataatc aaaaagcttc cgtaccaatg
     3181 actggtagca acggtttcca atcttacgta ttgatctctt gcttgttgct aggagcaggg
     3241 ggactttctg cagttgttta ctttaagaag aaagcctaga aggatcagct aatgattatt
     3301 cgtaagcccc caaaaagaag agtcatgcac aaactgatga tatttttttg gttgctgtcg
     3361 gcagtagcag tctatttaat tccagttgtg gaaacaaatg tagcgaaatt tcaacaacag
     3421 caaagaattt tagccattga aaatcttgaa aaaacagatt cttctttgga tgttgcgaaa
     3481 atagagttag gcgatcctgt tggtgttctt acaattccaa gtatttcttt aaaactacca
     3541 atttatgacg gaacttccga caaaatttta gagaatggtg tagggattac ggaaggaact
     3601 ggcgatatta caggaggaaa cggtaaaaat cctttaatcg cggggcacag tggactttat
     3661 aaagataatc ttttcgatga tttgccttca gtaaaaaaag ggcaaaaatt ctttattaag
     3721 gtaaatgaag aacaacatgc ctatcaaatt tatcgaattg aagaagttaa agcagaagaa
     3781 ttacaaaaaa attatttaga ttatcttatg cctgaaaaag accaagatag gatcacgtta
     3841 atgacatgca caccaaaagg tgtcaactca caccgctttt tagtgtatgg tgaacgagtt
     3901 tccttcagta aagaagattt aaaactacag aaaaaagcaa aaaataggaa atcaatttca
     3961 ttggattggc gattagcact gctattcgct tttttttgcg ttcctattat ttttatttat
     4021 aaaaaaataa ggaggagatc ggaatgaata agagaaaatg gctgtttgtt tgtgtagcag
     4081 ctctcttttc tactgtagct tattcgcaac tgtctttcgc tgacagcagt gatagtagta
     4141 ccactcaaac aatagataat tcaattactg caccaagcga aacggacagt tcggagaata
     4201 ctacagaaga aacggcagat tcaaatataa gctttactga atcaacgaat ccaacgtcag
     4261 aaagttcttc agagacttca gaaaagccgc aagacgtaga agatacgcaa gtgatcaagc
     4321 aagccattca tattcaaaaa attatttctt cgaatcaaat caacaatcaa ggcagtcaag
     4381 tagcccagca agaaggtatc aatggcgcga agtttattgt ctacgatatc acgaatatct
     4441 tagaagaaat gtcacaagat gataatgaga aaaatcaatc tgtagaaata attgagtcaa
     4501 aattgaaaga tcgagcaaaa aaactttcat acgaccagtt gaaaaaagtg gctgaaggag
     4561 aaaccaaaac gattgatgat caggaaggcg tgattgaatt ttccattgaa gtacctgcaa
     4621 acaaaaaaca agcatactat atcgttaatg aatcaagccc tgaaaacatt tcaaacagtg
     4681 aagatattgt tttattgaca cctgtttcaa atgaaaaagg tgaatttttg acggatgttt
     4741 ggttataccc taaatcagag aaatcagagc cgaaagaaga aattaaaaaa gttgtgtcaa
     4801 ctggtgtaaa gaagaacttt tttgaaaatt gttgggaatt ttttgctcaa ttattttttg
     4861 ataattagga tgaaatgatg aaaataataa gaatattagt ttttaatcta tcctttttag
     4921 ccgcaacaat attgtgttgc ggtttaattt tttctcaatt atcaatttat ccaagatatc
     4981 aacgattgtt cattcatttt ctaaacattc aatgtgcttc catgccatta gaggtgatta
     5041 aaaagctctt gatcaatcca atttttatgg ttagtttggt tcttcttaca ggattggtaa
     5101 cgtgggtatt aggaaaaaaa gaatgaaaag cttacgatcg tttaaaaaaa tattagatgg
     5161 agggcattat ggaaaataaa attcattgca ctacgggaag agtaattact ttagtgttgt
     5221 ttttgttcct tcttcttttt gcgaggggaa ctgcagtcca ggccttagaa aaagttgatc
     5281 cgagtcaaat caaagaaaat aataatctgg tgctttatca tgatagtgat tcattgagaa
     5341 atatcgaagt aactgggatc aatggattta agatactaga tgagtattca actaaaaaac
     5401 aaaaagtact tgcttggcca aaagtcaaag atttgaaaag tacgtcaaaa atcgttgccc
     5461 attatcaaaa agtaggtact tatctaggaa aagaaattga ttgtgacgtg actttttcta
     5521 attttgtagc gcacgctggg gttaaccaag acggattagc taaaacaatt aatggcaaaa
     5581 agtattataa ttatttgctc tttgataaaa atatttatcg aggatttttc atgcagtcaa
     5641 tcaatgtcat gaatgcaaaa ctagaattta agtatgcagg aacaaaaaca aaagtagctt
     5701 tgagtgaacc acagccagaa attcaatcaa aaatgagatc gatgagagca gctggtattg
     5761 atttaaacga tacatttcta tccatttaca gtttaaatgg acagtatcag caacgtgtgt
     5821 cttggtataa tgacaataat gaatctgtcg gtgaacgtaa tattgatatg agagaatttg
     5881 ttgggtatga aaaaatgggt agcttacctt attttgtcac aacagataca gcatgtgcag
     5941 aatacaaagc tcctgcgtta tcaacaaaca atttaacttc aaaagtagtg ggaggacgtg
     6001 cagaaaaggc ttatagctcg aatgatcatt tcaccgatgt tgtaggagct gatacttatc
     6061 acagaagtgg tgtaacgtat acgcttcaag gcgcttcccc aacattcatg attggcgcaa
     6121 atacgaatag tatgatgttt agctttgata ctgcattgct atggacacca caaccatcga
     6181 agcctacaaa agaagtgttt aacaaagcta atactgaaga ggcagcacac aatattgaca
     6241 aaaaagtgat tccacaagga tcagatgttt actatcatat tcaccaaaag tttgatgcat
     6301 taacagtcaa cacaatgaac aaatacaaat catttaaaat cactgatacc tttgacagca
     6361 aaaattttga tatggtatcg gatgggaaaa actatgatgg cgcattgtgg tatgttgaag
     6421 cgaatggtac ttggaaaaaa gctgatacag gaggaaagtt aactgtatca ggtaatacag
     6481 tcacttatac tgcttctgac agctttttag ctaacgctgc aaattacggt agggattata
     6541 ttttgcagct ccatatgaga gcaaaaaatg atgcaaaagg aattgcacca aatgtggcta
     6601 ctgtaacgtt taacaatgat ccgaacaaag gaacacaaaa aacaaataca gtagaaaact
     6661 atttctctct taaaccaaat aaaaaagtgg aacaagatgg gaaagatgtt gatggtcgaa
     6721 atgatggtaa aaaaggaacg cctacagctc ctttaaatgc aggatctgaa gtacaatatc
     6781 tagtcacaca aaaatggcat acaaaaggtg tagacattgc ctcagatcat tacaagcaat
     6841 ttagtattca agatccagtg gaagatcgtt tgacgtataa agaaggttct gcgcgagtga
     6901 tagatatgag tacaggaaaa gatattactt cagaaggtac actaacctat gatagcaatt
     6961 caagaacgct gaagtgggaa gcttccgctg atttcttaag taaaaatctt ttagatggac
     7021 gagaaattca gctgatattt acagctaaaa ctcctttgaa tgaagaattg gatatcgaca
     7081 accaagcaaa agtttcagta gaaagtattg agaaagcaac taatgtagta acgattgggg
     7141 taaaacctaa cttacctcag atcattgtgc caaaaactgg atcgaatcat ttagtgctaa
     7201 ctgttattgg aagtatatta tttcttactt tagcatcatt gggctatgta gttttaaaac
     7261 tcaaataaat ataaaaacaa ggctgagaat cagccttgtt ttcttttatt tgaagattgg
     7321 attcgcacta ataaatacat tatctacgcc aattctacca gcagagtcaa ctacaaaatt
     7381 atgacctaat ccgagaatac tttggttatt ataaagtaaa tttgcattat gggcagggct
     7441 atttttccat cctaccatgg catcgatagc accatcgtct gataaaaggt catcaatata
     7501 cagcccagtt tgacttatgt tttctccctt agcaccgtag cagcctaagc tttccaataa
     7561 atcttggaaa gtaccaccac cagggcgata gtgactgaag ctgacttgta attctttagc
     7621 tcgaatatct gcagcctgtt gaacaatatc attgaattgc attggggcaa caccattttg
     7681 ttggcgataa tcatttaacc aagcaagttc tttttgacgc ataaagttac gtaattcgtc
     7741 taatgaaatc tttttatatt tgaatgtgat tgttttattt tgatcgacgt tattaatgga
     7801 tcgttggccg tttttatcca cggtaacggt aggatcgtca tttctgcaca agaaataatt
     7861 ttgatcagtc atgtttttcc aaggagtagc aaagctatcc ccttcgtata ctgtttttga
     7921 ttcactagag agaacagcgt tggtatcagc atttacatga ttaacagtca cattaaattt
     7981 acgagtgtag ttgaaaatat aattttgact ttcagtcaca ttgtttaagg ttactgaatt
     8041 tgttggttct acccgatcgt ctaaaacata tccttgaata gaaggagcag ttaaagtgac
     8101 actgtcaccg tgagtgacat tgactatctg ttctttcaaa atattaactc gtccttcgtt
     8161 tttgtagttg ttattgcaca acaaattgat ttgatgcact tgattataat tgaatgtgat
     8221 tgttgtatta cctgtgattg ttttgctttg agtatcatta ccaatcactt tgtagctaaa
     8281 attatcttta gcgccttcgc tatatttaaa tgcttttgcc ttagcagtgt aagtagaacc
     8341 agaagttact tttgcttgat ctgtagcaat cacttgacct gtttgattgt caatatggtt
     8401 aatagtaacc gtatattctt ttggtgtttc aggtttgtgt tgcaaccctt taaatgcagc
     8461 atcaagacta tttttagcat tgtttacttg tgtttgagaa accttagaat cgtctagtac
     8521 ttttttagca ttggataaag cagtctgaaa attattccaa gattcttctg taaaatctcc
     8581 tttagcagtt gattttactc ggttgtataa agcttgtaat tcagctttat tcacagtagg
     8641 aactggtttt ttctttaatc ctttgtaagc agaatctaat ttatttttgg cactatccac
     8701 ttgcttttga gtcgcttttg agtcatttaa cactttctta gcattgttta aagcggtttg
     8761 gaatgcgttc caggtattgt cggtatagtc accttttttc gttcccttaa cgctcgtata
     8821 aagagcttct agagccgatt tattcacttt gggtttagag gtgtcagcgc cataccaacc
     8881 gataccttcg tatttccagc catagtcttt ggttaaccat tgtacttctt tccaacttgc
     8941 agtgtagtga tgtgagccag attttacacc aggaaggaaa aggcggtaga tcggtttatt
     9001 atttttttcg gcagaacgcc aggcaggccc ttcataagtc cagccgtaat ttttagtcaa
     9061 ccatttcact tcatcccaac tagctgtgta atggtgatca cgaagacctt tattgtacaa
     9121 acgatagaca agatggccac cgctagtcgg tgcttcccag gcggggcctt cataatttcc
     9181 ccattttatc tttactagat ggtcacgttc ttttttgcta gaggtgtaaa aatgttcatt
     9241 attatttgga ttgtaaaggc gatacatgac gttagttgaa gcagcgtcaa cagatccagc
     9301 aagactaagt gaggcagcaa atgttccaat agctaaaaca gtttttggat taaataattt
     9361 cattttttca actcctaaat ttaattaaaa atgtttacat gattattata tatcggctaa
     9421 ccgatatagt caataaaaaa taagaaaagc cttatataat tttggctttt cttattttat
     9481 ttgttagttg aagtattaat atcaacgatt tcttcagcca atttatttaa tttcatagca
     9541 tttatgaatc tcatgttgtc tatactagag cgtttgttgg caaggtcact tactgtagtt
     9601 aagggtacgc cagattctat ggatatagaa cgaactgatt taccactatc aaacagcaac
     9661 cattcgattt tctttttatc agcgtacatt tcaatgctcc ttcttgtttt ttctttatta
     9721 tagctctttt ttgtaatgaa tcacaatatc aagagaaaaa ttttctatag aaaggtggat
     9781 ttttatgagt attcgttctc cgtgtatcca aatgaggttt gttgctactt tcgttatttg
     9841 atatactaaa aataaacaac gaaagaagga ataaaatgaa gaaaaagcaa ctatggtttg
     9901 tctctatgtt tgcaatattt tttattattt taagtggatg ttcaagtaat aagaaatcgg
     9961 aagctaaaga agataatagt ttattgcaac caggaactgt ttggaaagaa gaagtaggtg
    10021 gtcttattca taatttaaaa attatagatg atactacctg ggaatattct gaaagtgtat
    10081 ggcatccaga tcctgtacaa ataacagtta agaggcaaaa agactatgaa ggtttagaaa
    10141 gatacaaaat agtagattct gcaggcatta gggaatttat aaacaaacct gattcattat
    10201 ttattgttgt tccctatgag aaggatggcg taaaaaaaat aatttttctt ggatctagca
    10261 aggatgagaa gcgaacgaaa gagaaattaa ttcatgatgg atcagagtta aataaataca
    10321 aattacaaaa gactagtgag tgattgctag tctttttatt tatcctgaag gaggaatcac
    10381 agtggcaaaa gttaaaacac cattcgaaaa agccgcgtct aaaatcttag aacgccgtgg
    10441 tgtttctgaa atacagtgga aaaaagaagt tcttgaaaaa gcacaatttg acctattacg
    10501 aggaaaagat aaggacttag aagaatatat ctatcaacgt gaacgtgaaa aacttgtatt
    10561 cgatgaaatt attaaacatt aaaaggagcg aataatctta tgtttgaatc aattacaatg
    10621 aattttttaa ctcaaccgaa agtagtagct gcagttgata tttttagagc attacaaact
    10681 gccgcaacta gtttgaaaaa taatctgatg atttttgctg ctgttgcggc agtggcttcc
    10741 attgctcttg gaggtatttt cttcttcttt gggcgaagag gagctgaaaa cgggaagaca
    10801 cacgtaggtt atgtattgtt gggggtagga gttattttag ctgccgcttc tattgtagtt
    10861 tcaatgttct caatgtttgg acaaacccca caaggactat aaaaaaaaca agtaggagga
    10921 gtaaaaagta cgtggctact ttttactcct ttttttatga aaggagaata ttcatgtttt
    10981 ttacgatttc aggaaatgca aaattggata aagagttaat aagaaaagca acgaagaaag
    11041 tgggaaagcg tacttccttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag
    11101 aacagctaca tgtgttagga caagtgttag aacaagagaa tcaatcttct gttaaattga
    11161 ctctcacgtt acatgataaa gaaggaaaaa tagaaaaggc tggcacagaa tacgtttttg
    11221 gcccactgga ttatcaaatt tcagaaggtt tttatcctac attgatagat ttaatccgcc
    11281 ttgatgtgtt taaagatacg gatgaaacta tgagtgtgga agagtcttat cgaaacgaaa
    11341 aacttttaca agttttagaa gaagagttag agagcgacca aagaaaagtg aatcaagtga
    11401 gtgaagtcga agtaaatgaa gaagtaccat gggaacgacc aatctttcca aagaaggagt
    11461 caaaagaaaa agagacagtc tatgttgacg aacaagctga tattccgact cagaaatcga
    11521 tatttgagga agagaacgat gtgatgggtc aattggaggt agatcccttt gaagaaacaa
    11581 tggaggatga agagacggac gaagtagaag ttgatccagt tgaagctaat gaagagtcaa
    11641 catggactga aggggatttt caggaatata ttgaaccact tatcagtgaa gaagtagaaa
    11701 aaaacgaaac agagatacaa aaggcaactg tatttgatta tattttggat caatatccgc
    11761 cagagcatga atggatgaaa gaaaaaaaca aattattttt aaatgagctt tattcgaaat
    11821 atcaattacc ccaaacctat caagcatttt tagagagtaa agaagaatta atctcacagg
    11881 gtaaaggcac acttttagaa cagttagagt ctgtccaatc aacaaattgg catgagcttg
    11941 cacaagaaga tttattagcc acctttgaag aacgtcaaca agaaacagat caagaaatta
    12001 atgagtatgc gacggaacag tcgtctaatt gggagaaagt aaaagaggaa ctaaataaag
    12061 aagaacagcg agtgattgaa gaagaagtac aaaaagtcaa agagcggtac gaaaagaaac
    12121 gcgacaatgc ttattccttg tgtgtagaaa agatcaacaa ttttactaag acgaatcaag
    12181 aagcgttatc gaaagaaaaa gaaaacttgt taaaagaacg tattaaagaa cgaaaagaag
    12241 agttctaccg cggtttacgt acagataagc taaagattag caaagaatta aatgaacaac
    12301 tgaataagct atatcaaaca acgactgaag ttcttatgga aaaacacgaa cagatccagc
    12361 aagaattaca agtacaaatt ccaaaatgga aaaaagagta tgaaattcaa caacaagaat
    12421 tgaaagaaca agaagaaaaa caacggcaaa aagaaaaaga gcgtgaacaa ttagaaataa
    12481 gaaaacggga acaggatctt gcggaacaaa aaatggcgat agaaaaacaa cggttagagc
    12541 aagaaaagga aaaagaagca gctgctcgta aggaacgtca agaacaaatg gatacattgc
    12601 gtcaagcaca gttgaattat ctagcacaac ctcaaccagt agctgctgtt caaacgccag
    12661 tgaacaacca agcaaattta actccttcac cccagcgttc ctttaacgga tggatggtgg
    12721 gatgtattgc aagtttaagc ttgcttctag gtggaggaac agtatttgct tttaatcata
    12781 tcaatcaatc ttcacaggct gattctgtag ccacaacggc gtcaatcaag gaagaagccc
    12841 aggaacaagc aagaaaagag tatgaacaac aattagaaga attattgaat cgtaccaatc
    12901 agtcaacaac agagtcaagc atggaaaata gcaaagagag tgattctagt aaggctaaag
    12961 aaggatcaag cgattcaact gtacaatcaa acacttccga aagttcagaa tcaaatgagg
    13021 tgaaataatg cgtgttagag aaacaacgaa gcgaaaagac aaacgattca atttagaaaa
    13081 gaataggtat ctttctcatt tctatcgcta tactccctca ggagaagagc taccagaaaa
    13141 acatgacaaa cgcatttcga aaaagatttt ttatagtgga cttgtatacc tccctttaga
    13201 gtatttagta acaagagtac cagaagtttt caaccgattg gaaattgtta agggaagctt
    13261 acaaggaata aatctgtttc aattacagga aatgccacag gtctttcatt ttgattcagc
    13321 tggtttttgg aatccattta ctcctacaac tagtttgggt acacgtttag caatttcgac
    13381 agtttgtgtg gttccagctg tacttatggg attgaaaatg gacatgtggt ttcgtcctct
    13441 agcagatgga caaaaagggg ataatcgatt aatgacctta aaagaaatcc aacagattta
    13501 tccgcaaata cctgaaacaa aaactacttt tccaggttat ggaggtattc caatcacaca
    13561 ttacaaaaaa tattggtaca ttcaaacaga tactgttaat acgtgtattg ttggtacctc
    13621 tcgatcaggg aaaggtcaga ttgaagtgtt agccaccatt gacaatttat ctcgtgcaga
    13681 aaaacaaagt tcaatggtcg ttaatgatcc aaaaacagaa ttatatgttg gtagtaaaga
    13741 tgaactagaa gctagagggt atgatgtata tgcctttaat atcaccgatc cactgcaatc
    13801 aatgagtgat aatccattgg cactcattgt gaaatactgg aagcgaggag acatagacac
    13861 cgcaacacag ttaaccaata cttttacgaa tacgatttat tatgatgcaa atgcttcaga
    13921 caataaatac tttaacgaaa atgcgcagaa agctgtcaat gcgcttattt ttgcgttatt
    13981 ggaacaagcg gatcaaacag gggattactc caaattaaca ccaaataatc tcgttgaact
    14041 actttcagaa attggcggtt ttaattatta tccagatcct gagaatgaat tcaagcagct
    14101 caatgcctta gatgagttca tgaatcagtt accccctgga aatatagcaa aaaaacaata
    14161 tggggcaaca aaaattggat ctgataaagc gaaagggaat atcttgtcta cggcaattac
    14221 aggattgaat ccatttaccc taacgaaaat tgcgaagatg acttctcaat cgaccattga
    14281 ttacaagtcc attggttttc cgaagtattt ggatctcaaa ttacatgaaa gcctattaaa
    14341 tcaacgcatt gtcgtggaat tttatcataa gggaaagaaa tttcacgagg aacgagtcaa
    14401 agttggctat cgtggttttt gtgaaatcaa ctttgattgt catttagagc agggagatca
    14461 tgtttgctta aaatacaatc atcaaggaaa acaatatgtt gcttggtatg agttttctca
    14521 aaaagtattg aaagacgaag agggaaaaat cgtttatcga aaaaaacgag gagaaactca
    14581 tttgccagaa ctagaaaaag aagccgttct aacattagat gagaagaaaa gtaacctatt
    14641 agtagagtct attcggatgc actataccga taaaccaatg gctattttta tgttaacgcc
    14701 tgattatgat ccatctaacc atatcattgt tagcatcttt cttagtcagt tgtataaaga
    14761 attatctacg caatgtgtta agactaaagg agataaatgt caccgtagga ttcattttat
    14821 tttagatgaa tttggaaata tgccaccgat ggacaacatg gaaggaatca tgacggttac
    14881 ggcaggtcgt aatatgttat gggatctgtt tattcaatct tatcagcaac tttatgcgaa
    14941 gtatggagaa caaaacgcag cgattatcaa agaaaattgt cagacacata tttatattat
    15001 gtcgacagat gataatacca tcgaagaatt ttctaaaaaa gtggggaata agacggttga
    15061 acaagagaac agtaccatca attcattagg tatgaatact catatcaatc gcaatgttga
    15121 ttcagatcgt atcttaactc ctgaaagaat ttctactttt ttagaaggtg aaacgattgt
    15181 actcgctcct ttaaaacgac aagatttgaa aggtcataaa atacggccgt atcctatttt
    15241 taatcatggg gaaacgaatc ttccttatgc ttatcaatat attgaagatt tcaatccatc
    15301 gtgggatatc aatgatatag acatacattg tacacatgcg gacttggatc ttaaggcttt
    15361 acaaattgat tatgattatt tcctaccaga tgaatatgct agaaatctct atcatggact
    15421 gcatgatcaa ttagaagaaa aaaacgaaga aaatatgttt tataaaatcg ttcaatcttt
    15481 tgagaatgag acggctaaaa aattgttaat tcaattttac gaagaacaag caacggatcg
    15541 tcttcaagaa tatgttgaaa agttgatcaa aaatgaagaa atttctgaaa tgattaggaa
    15601 acggctgtta ttggaagctg aaaaggcggt gaaagaatga tcattggagg aattttctct
    15661 ggcatagccg actggtggtc aggtttattc ggagaagggg atgcagatcc caaaaccgta
    15721 acgaaagtct tacaagatta tggtaattat ctgcagtatc aagatgtatt cagttggatt
    15781 tgtaatactt ttttatgggg attgatcaaa gggttatata atctcaatac tttattagaa
    15841 aaaacaattt atcaaagctt tgatttaaaa gacttattga acgccgctgg tgttaatgaa
    15901 ctatttcaaa gtttgattag taaggtattg gctctttttt gtgtcgtcac attaatttat
    15961 ttaggcttga aattttttat gagtaaacac ccaccgaaag tcaaaaatat cttggttaat
    16021 ttatttatgg ccatgatctt gatttttggt ggtagttctt taatcgatga agggttaaat
    16081 atcagtaaaa acttttatgg agacgtcact gcagcaaata aagcagataa aacgggttca
    16141 cctgcttttc aaattattca aaataatgtg attgatgtca gtacattact agcgactgac
    16201 ccgaataaag tagaatcctt accaacagat aaaagaaatg ctttaacagc gaaaaatttc
    16261 aaaacagcga atatcaatgg gattattaca cctgatcaag ctaagaaaat gtctgaatca
    16321 agtgatatta gtacagtaca aaaagatcgg ttaaaggcat tacagtatcg actagagtta
    16381 gacgataatg ggaaagaaat ccctgttcaa attagtgatg aaggtttagc aaaatatgtg
    16441 tatacgtcag gctatcgtcg atacattagt agtccaggga ttattttggc tggggaatct
    16501 tctttgtcgg tagcctattt atttattttg tttacaatcg ttacttgcat tattgagcta
    16561 gtatttaaaa aattctattt agtaattgcc gcgtcaacgg actttgagac aggacaacgg
    16621 atgaaaagtg cgatagaaga tatttctcaa tccttcttgt tattggcgtt tacgatttta
    16681 gaattacgaa tctatacatt aatgctttca ggtatcggtg atttgcatgc ggtaggaaag
    16741 atcaatggat tcttgtatgt tgttgcttta attgtgctaa ctattgcgct attcaaaggc
    16801 tctcaatcgg ttacgaagat tttcggtgtt gatacgagtc tgaaaaacgg cagcaattct
    16861 cttcttagca tgtttgcctt aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac
    16921 cttgcaagtg ctggtaagag tggtttaagc catttaaatg atattcgtaa gaatggattt
    16981 ggccatcgaa aagatattac ccatgataac ggggaagaac aatcagacga taaagctaca
    17041 actgtaccta atagtaagaa gacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt
    17101 tctaaagccg cagaaggtct tggttacgtc aatgaacgtg ggttaaaagg aacagttgaa
    17161 gatcttacag aaaaagccaa agacacctta gaagagaaat tagacggcac gagagctaaa
    17221 gaatttgctg aagctgtgaa gaatccatcc gaagcactag aaaaacaaaa agaaaaagct
    17281 tcagcagtca aagaaggact aaaagatgcg tatggtgaag gacaagtcaa tgcagcagtg
    17341 aaggcaaata caacaagtga aaaagaaaat caagaaggtg cagcgattcc ttcagccaaa
    17401 gatcaccaag atgagttaca ttctaacgaa aattcgatcg gagaaaaaga ttcagaagaa
    17461 ggacaacatg gtcagttacc aaaaaccgat ccagaacaat atcgttataa atctaacatt
    17521 aattctgaaa acgaaaaacg catttcagat ttaccaaaac gaaatcaaga agtacaaacg
    17581 gatgaggatt ccatcgatct gccaaatgat aatggcatcg aagttggaac tgaaaaatca
    17641 acgaaaattg gtttgcctaa gacacaaaat ttaccaatga aagatagtcg tttgaatcaa
    17701 ttcaaagaga atgatcaaag ctttgttcat caatcacctg caggtactgt tcaaatgaaa
    17761 tcaagtcgtt tgcctgaaaa tggaaatctg acaactgttt cttacaattt agctgaaagt
    17821 ggtgaaacag agaatgcgtc cgttcaaaat attgtgacaa aagaagctgc acctaagcca
    17881 atcaataaag ttcataatgg atacagacca gcaaacgtag catttactgc accgacaaaa
    17941 ataaatgtga caagagaaac taaaaacagg aacaatgaat tgaaagaaca actattgaag
    18001 gatatcaaac cataaaaggc ctatttaagg gcctttttct ttataaaaca agtttaaaat
    18061 ggaaaggaga aaattgtgga ggatatttta atagctacgt ttataactgc actgggagca
    18121 tttttaacga tatttgtggt gactattaaa ggatttaaag atacggatag tttacaaaaa
    18181 gatcatcagt ctattttaga tggtcaaaaa acacataccg aaagcattat tgtacacctt
    18241 tcagaaggat tcacttattt gaaagatgct atgcccacat tcacagtaaa attaacggaa
    18301 atatttcatt ctgttgagca aatatcgtca gaattgaaag agcaaagaca acaaaaagat
    18361 cgtcaacttg gctcacttaa ttttaggcaa gaaacgatac aagaatcatt ggagaatgta
    18421 aatcgattaa acgatgaaat gcaacgagtt catttggaaa atgaagaatt acgcgcacaa
    18481 aattatgatt taattcaaaa gaaaagaaat ctggaacaaa aaattgttga attaaaagaa
    18541 gaaaatcgtc aattgaatta tcaattacga cgaggaaaaa atcgttctcg tgatttagga
    18601 aatgaattag agttgtaata tttagaaaaa cgctgtgaga aatcacagtg ttttttattt
    18661 ctaaaaatac aaaatataag gggtatggtt atattatgga taaatacatt catatgaaaa
    18721 atcctccaag atttagtggg gaatggaagt ttttcgcctt tttcttttta gatctattaa
    18781 cgcttggtgg ctgctttttt tgggcgaaaa tagtcaataa tcttgtccac ttaccactct
    18841 tttttgcact cttgaattat ggattatggc ttgcgatagc gttagtgatt gtttggcgac
    18901 cctataataa ccctggtcaa cgccaaattt ttgcgattat cgaatctatt ttctttacgg
    18961 ataagaacca ctatcatgcg ttagatccta accgaaatta tcatggtacg tataaggagg
    19021 atgaataaat gcgagtcaaa ggacaaaatt cagttgataa gaaatccatt ttgcagtttg
    19081 gaaaaccaga agagcgctct atcttggact tatttccata taaatcctgt acagaagagg
    19141 gagtcttaat tactagagaa gatcattttc agcgttatta tcgtgtcgtt tccactgacg
    19201 tggagggatt aaatgaacaa gagaaactag aacgaatgaa tcagttgacc accgtcatgc
    19261 gtacgtatgt gccaacaatt aagttagtta gtttgaccac agagacggat ctaacggaac
    19321 aaatcgtgca aaagcggcag ttattagata aaaatcgtat ggaacagtca ctaggaagaa
    19381 atctacagcg attaagaaaa tatgaaaaga aattagtaga ggagatccag gaattaaaac
    19441 gggcagaaca agaacgtcct gacttaagct tctttttcgt tattgaagga aagacaatca
    19501 aggatttaca aactagaaat cgtcagttaa tgcgatctag tggcatttta gggttaaaac
    19561 cactctacaa aaaagaattg attaagattc tttatcgaat gaacaacatg aatgacgaat
    19621 aaaaaagatg gaggaaatga ttcatgctag atgtgataaa aacagctttt tcaacgcaaa
    19681 gtaatcaaaa ggtgattgat ccattaaaac aacttggtaa tcgtgaaata gagattttaa
    19741 aatcaaaagg ttatgattta gatttcttaa aacaagtgat gccacaaggt gggttgaatt
    19801 ttgatgaaga atatgtgacc tatggaaatg gttattcacg atgtgtgaca gtttatcatt
    19861 acacaaaaaa tcctactctt ttttggttgg ccaatctcat gaacaatcct catacagtgg
    19921 ccacactaga tgttagcaca gatgaaaagc aaaaagtgat tgatcaaatc aaccgcgcat
    19981 tagatgaatt aaatgatcga tcagataatg aacgaaaagc gactgaccga aataaaagtg
    20041 cggaagaata cctggaacta gcggaatatg cccgaaaatt gacttctaat ggggaaattt
    20101 ctaaacaagt caaagtgaga gtacatgttt acggaaatac gatccaagaa gtggatgaac
    20161 gggcgcagga actgatcgaa aatctaaaag ggatggatta tcgtgcggtg acttatctgc
    20221 ataaaaccaa acgagattgg caatcgatgt ttaccatgtt cgatgaacaa gctgaatggt
    20281 ttggaaatat caaagggcaa tcacttccat cgttaaacat tggcggagga ttcccgttcc
    20341 accaccaaac gctaaaagat ccaggaggca cacaatatgg ggaaaccatg acaggcggcc
    20401 catttgtctg gaatgccacg tataaaaata gtgtacgttt atctaccaat accttgcttc
    20461 taggaatgat gggagctggt aaatcgaccg ttcttaaaat gatcgcggaa gcccatttag
    20521 ctgcaggaga ctttatttgg ggctttgaaa agggaaaaga ctttattcct ttcttaaagg
    20581 aatataacgg tattatggtg cgtttagacg gatctgacgg aatgatcaat cctttagaga
    20641 tatttgccac acggacgtat gatgaagcat ccagtttata tgacgatgga tcagtcaaag
    20701 atttgaagat caatgaagca gcgtcctatc aaacacactt agacaaagtg gtctatcagg
    20761 tacagttagt gagtcctcag ctaaaaggaa cgatgaaagc agaatttaag acctacttaa
    20821 atcgttttta tgaagagtat ggaacagtac cacgcggctt tacttcctca aattcgcgtt
    20881 caaatactga tacgcaagtc acagggaaag atccagaagc ttatccgacg ttcaaagaat
    20941 ttttagcctt tttaggacaa ctggaactac caggggcttc ccaagagaaa aagaatcgga
    21001 aagaagaaat ggagtctatc gtggaatcct tatgtgagac ttatggcatg atttttgatg
    21061 gtcatagtac gattcgacac cttgaccaac aacagttggt cttttttgac attgactcta
    21121 ttacaggcct agatcgaggg gtacaacaat gtcagatgta catggccatg acgttgattt
    21181 ggaatcaggc attgattcaa ggacgaagac aacgacgctt aattaaagaa aaacaaatgg
    21241 aagaacaaga cttcaaacgc ttcttggcga tgattgatga gtgccataat ggtgcgacct
    21301 gttctgcagt gaaaagctgt gggttgcaag tagtctaaaa actattgtaa taactcttat
    21361 aacgagaagt caaatgagtg ggtaacgcca caaagggctt ccactgatac tccgacatgc
    21421 aacaagtagt ttatgcagac caacgttgtg tgaagctcgg tgaagtcggc tgaaggatac
    21481 cgtaaggtaa aagaaatagt gaataccacg aaagttctct agaggtaaag ggtgtatccg
    21541 ataagtcggg tgtccaaaaa aacttaatat ggtgagtatg tacaaacgta ctgacgaact
    21601 agcgaatgta ctgtccgaaa ggcatagctc ctagaaatgg gagagacagt gagcaaaaaa
    21661 tcactcattg tgctaacttg tggttgagta aaagtcgttg ttatgaaaga ccatgctgcg
    21721 ttacaggcgt aggagaagtt agggggcaaa agctagcatc taagttaagg catgtggata
    21781 gatataaggg aacaggggaa gccatcaaca tggagagtgc atactcgatg aagtggtagt
    21841 aagaaatatg tgaatgacaa ataacttact ttagtgatgg tgaaagtaga gtcacgactg
    21901 atgaaggttc tgtaatggaa ctggaggaac aggctcgatt cgtctgtaaa agtcatgaaa
    21961 cccgttcaac catgggattc tcgtatgact aaaaaggtca cgagccaatt ggagcgtgat
    22021 aaaccatgac aaaagaaaca agtccaaaag ataggaagtt gcggcatgca gaatattatg
    22081 gcatgacgga aatcttcgat aagatatact ccaaaagttt gaagggagat aatttcaaga
    22141 atctaatgca gattatcatt tctgataaca acattgtcct agcatatcgt aatatcaaga
    22201 gaaatcacgg tagtgtgaca agaggagaag atggagtaac gattaaagat attgaaaatc
    22261 tcaaccgtaa tgaattcgta gaaattgtta ggaagcgatt cgcacattat aaccctcgga
    22321 aagtaaggcg tgtagaaatt cctaaatata atggtaaatt aagaccgttg ggtattccat
    22381 caatatggga tagaatcgcg cagcaatgca tcttacaagt attagaacca atatgtgaag
    22441 caaaattcaa taatcacagc tatggtttcc gcccaaatag atcagcagaa cacgcaatag
    22501 cagattgtat ggcccgaatg aatcaaagtc acatggaata tgtggtagat gtagatatca
    22561 aaggtttctt cgacgaagtc aatcatacta aactcatgag acaaatctgg tctatgggta
    22621 tacgagacaa acagcttctc ttaatcatta ggaaaatgtt aagagcaccc gtagtacttc
    22681 caaatgggaa gttgatatac ccaacaaaag gaacaccaca aggcggaata cttagcccat
    22741 tacttgcgaa catcaatctc aacgaatttg actggtggat agcaaatcag tgggaggaaa
    22801 aagatgccaa agagctaaaa catcatttta ggaaaaatgg agcttgggat aaaggtaata
    22861 tctatcacaa gctcagaaag agtacaactc taaaagaaat atacctagtg agatacgcag
    22921 atgattttaa aattttctgt agaaattata atgaagcgaa aaaagttttc tatgcaacta
    22981 aaatgtggtt acaggagcgt ctaaagttac caatatctga agaaaagtca aaaatcacaa
    23041 atctttcaaa agaagaaagt gaatttttag gctttacgat gaaattagtg accaaaggta
    23101 acaaaaaggt tgttaatacg catataggta caaaagcaca aagcatgatt aaagtgaaac
    23161 taaaaaaaca aatcaaacga attcaaaaaa gtcctaatag caaagatacc tttatctata
    23221 ttggagtcta taacagtatg gttattggga ttcataatta cttcaaaatt gcgactcatt
    23281 gtagtgtagc aatgcgaaaa attgcaagag aactcagacc aagttttgaa atacgactac
    23341 gagaacaagg aatctcaaaa gaaggacaat acggaaagta cgaaggatac aagccttacc
    23401 tacggtcagg acaaatacga tatataagag ggtttccaat attaccagta gggtatattc
    23461 aacacagaca tccgatgtgt aaaaaaagaa atattaataa atacaccgaa gaaggtaggg
    23521 aagccattca taagaagcaa caaaccgtag aagaatggaa gatatcgtgg ttgtgtagca
    23581 atccagtgct tagtaagaga gcaacgattg aatttgcgga caatcgaatt tcaaaattca
    23641 tcgctcaaaa gggaagatgt gcagtaacag gtgaggagct tatcttatct gaaatgcatt
    23701 gtcatcatat tatcccttat catgaaagca aaagtgatag ctatgaaaac ctagtgattg
    23761 ttactgagga ggttcatcgg gtaatacacg ctacacaaag tgaaacgatt gaggaacttc
    23821 taaaatatct aaaattaaat ccaaaacaaa aagaaaaact caatgagttg agattaaaag
    23881 ttggtaacga agaaatatct taataaatat ttgtaggacg ggaaaacaga atgtctttta
    23941 tagacgaggg aacgccgtat gcggtgaaag tcgcacgtac ggtgtggact gggggaaaag
    24001 acggagataa tatcaaactc ttacctatca gtatcgatta atccagattt tattgaaacg
    24061 gtaaattatg tcacaaactt tcaacgagaa atgcgtaaag tagaagcaat gactgtttta
    24121 gctacacaat ccccacaaga aatggtgcca gaaaatatgt cttctgataa cttctcgaaa
    24181 ctgaagaaag tctttgaatt ttcttctacg aagatcttta tgcgtatgga tgaatctatt
    24241 ttacgtcata tagaaggatt agtgggtaaa tcaatgacga actcagaatt agaatccatt
    24301 cctcaacaaa atcaaggaga cgctgtgatc aattttggct caaaagaaac cattcgtgtt
    24361 cattttagtc cgaacaaacg tcaattaaaa ttgtttgatg gaggaaaata atggaaaacc
    24421 aaaatgaaag tttaatcaag cagtatgtta agcgtcgtgc aaagcggcgc ttatttttgt
    24481 ggttgtttgg tacttctgca ggtttgatta ctattttgat cactgtgttc gtgaccctat
    24541 ttctaatact tgcggcgggc tcgattgata attcggattc agattcaagc agtggtggcg
    24601 aagcttttac aggagaatat tcggaaggct taccgattta taaagaaatc aaaggaagag
    24661 gccctttttc tgatgagatt gcgcaatatg ccgtaggtgc agcagtgaaa tataaattat
    24721 taccaagtgt gatcctttcg caatacggtt acgaatcagc gtttggtaca tcggcgtccg
    24781 caagaaatga tctcaactat tttgggatta cttggtttga tggttgtctg tttcctaaag
    24841 gaactgcacg aggaattggt ggcattgaag gtggctggta catgaagttt cccaactcaa
    24901 aagctgcatt ttcctattac ggctttatgg tagccacaca atccaatttt aatgcttgtg
    24961 taggaaataa aagccctggc gcaagcttat tgatcttagg acgaggcggt tatgccgctg
    25021 caggaattac ggaagatagt ccgtattata caggttgtat gtcaattatc acttctaata
    25081 aattaaccga atatgatgaa ttcgccatca aacattgggg tgaaggtggc aataacaacg
    25141 gcacgattac tggtgaatgg acgaatccat tccctggcag cagtttagat aaaagttcct
    25201 tcagcggtgg tcaattattt ggaacgaatc caggcggtga attccgtccg aacggcttcc
    25261 atgatggatt agattttggt tcagttgatc atccaggaag tgagattcat gcggttcatg
    25321 gcggaaaagt cgtgtacgtt ggcaatcctg gtatttcagg tttgggcgcg tgtgtgatcg
    25381 tgattaatta cgatggcttg aatatggtgt atcaagaatt tgcaaatagt acaggaaatt
    25441 ctcgagtgaa agtaggcgat caagtgaaag ttggtcaagt aattgggata cgagatacag
    25501 cacacttgca tttaggattt actcgaatgg attggcgtca agcacaagga catgcattca
    25561 ttgatgatgg tacatggatc gatccgttac catttttgaa tagcagtaaa aaatagatca
    25621 ggagaaaaaa tatggaaaat aaaacgttaa aaatcgtctt aacagctgca attagcgtta
    25681 gtttaatcgg caatattgcg ttgttttggc agctgaaaga ggaacaagca gcaaatacct
    25741 ataaaattga agaagtggct aaaaacgcgt ctgagaagct caaaaaaaat tcctctgagg
    25801 cacaggcgaa gatcgacaag ttaaatcaaa ccatcaatga gaaaaaccaa gaaatcgatc
    25861 agctgaagca acaagatggc acaaaagcaa aagaggaagt aactgaagca caaagaaaga
    25921 cggcagaaga gttcggtcaa ttggccattg ataaatcatt aagcagaaat gaattaacgg
    25981 aaaaactaaa agatgtcgca acccaagaag tgatcgacaa attaagtcct acagacgatg
    26041 atcaccaaca tgatgattac ggaagttact cctttacatt aggtgacgtg caaacttacg
    26101 ctcaaacaag cagtgtaaaa gaggaacaaa attttgtcgt atttgttgat tatacaatcg
    26161 gcaatccgca attcaaagat gtcaaaccac aaaaaataaa aggtggatta actgtcactg
    26221 aaaaacaagt agatggtcaa tggaaagtca tagactttag ttatttcact cgttaggagg
    26281 aagaaaatga gtaagaaaaa aggagaaaga caacgtttca aaaaacgaaa aagttatctt
    26341 agatggctgg gaatctttat gattctcggc tttttgattc ttgctagtcc gatttatacg
    26401 aatcagaagg tagatatacc agatgaggta agcacgaacg cctttttaaa cacgaaagag
    26461 ctgacaatgg tttcaaaaga aaaaggagcg aaccagcaat tagtttttga atttgcgatc
    26521 gatgatgaag atcaaagctt gttaaaagaa ctggctaatc ttaattatcg cgtagaagta
    26581 aagacagcta aaggggatta tcaagcaata cgagccaaag tgattaaggt gtctgatgat
    26641 tattttgcag tgaagctaac gcatgtacca gaagaatata tcgccatgcg tttaaccatt
    26701 attcctgaaa aaattgatcc aaaagtggat atgcaagaac cacaagatct gatttattac
    26761 gtgcacgaag ataaggttaa agatcaagtg aaagatgaag attatgaaca acacgcgatc
    26821 aattacaaag tgaaaggata caagaaagaa caaaaagcag ctcaaaaaca aatggaatct
    26881 ttccaagcaa ccattgattt gaatgaagaa ttagtgaaga agctaaaaga tcaattgcct
    26941 tatcaagtcg cagatgatca ggaaaatact gaaaacaaga ttaatagcta ccagcaagaa
    27001 attgaaacat cgaaaacgca actgaaagat caagaagaga tcattcaaaa acttcaagaa
    27061 aaaattgatc gtatgacaaa agaaaagatt tagaaggaca ggtggagtga aaaaatgaag
    27121 cgaacaaact tggctgacaa agatactttc gctgagcaga aagtattgat taaagcctat
    27181 ctcaaagttg taaaagctaa agaaatatgt cgagaagtga atttatctaa cacaacaata
    27241 tctgagttga agaatggtcg aaagaattta gatactttaa aattcagatc atttgaagct
    27301 ctatatgtag ctgctaaaaa atattttaca gctgataaca aataaaaaac aggagtattt
    27361 tatgtgaaaa aagtatataa aaaatgctta tgaatcagct atatcacctt aaccatttgt
    27421 taatgagatg ggagaaaaca ttaaccacga ttctaacgca aacatcaagc acataaaaca
    27481 tttaacactc ctcctttctg gctgaagatt tcaaccaaac aggaagacag cgtatcaatt
    27541 atagcataca ctttttctta aattcatttt tcatatgaca aaatatttcc ttctaatcga
    27601 caaagttaga aggatttttt attgtctaaa tacacaaata accttaattt ttaaagagca
    27661 taaggaaacg tgatatcact ttctcacgaa aggtgttagg taggctgtgc ctaccacgtt
    27721 tctaagaaag ataaatgata tcaaaatttt ggatttgtgt gtagatttgt gggtaggatg
    27781 aaagcgaatg tgggcagtaa aataagcgtt tgtgtgtagc aaaatcaaaa aatgtgtagg
    27841 gatatgtgta gctacacata tccctacaca taataaattt ggaggaaaat atggacttat
    27901 taattagaaa tattgaagaa aagtatatta ataaaattga caaacgttgt gaagaactta
    27961 cggtcaagac tggcaaaaaa tggagtcgaa atcaatacct aaaagttttg atcgaaaatg
    28021 attttgatca cgctcttctg aattataaaa aagaccaatt tgatcggttg ttagaaaaat
    28081 ttgtggatat tcaaacttat aatacgaaaa ctttagaaga atatattgca acaaataatc
    28141 aattaattgg tttgttaatt gaataataaa aatagtattg tgaatttata aaaggaggaa
    28201 atcaattttg gcaaaagcaa caagaaaaca tgtatatctt tacgatatgc atatcgaagt
    28261 acttgatgaa ataatttcta ctcatgaaga tatatctaat tatagtgaag cagtcagaca
    28321 tttgtgtatg atgtatgatc caaaaatcga agaaaaaata aatccaattc aaattaaatt
    28381 gaatgcaatg ggaaaagaaa tttctatttt aaccgaaatg gtttcagagt ttgcggatct
    28441 tcatttgaaa gatacaggaa tactaattgg tacaaattca actgtttatc aagaagcaga
    28501 agaacgtgtg gaaggaaaaa ttaaatccaa tcaaaccaaa aaatattctt ctaagttaaa
    28561 gaaaccagtg aatgaatctg ttcataccag agtagatcca tttgatccaa cgaagattct
    28621 aaaaagataa aagtagaagg agaacgtgat gaataaatcg cctgcagtta ttcttacttg
    28681 tcaatttacc ttgcccaata aaaaatcttt ttcaacatac attgattata tgacaagaga
    28741 aaaagcactg gaagaaatgg aacgacgtac gcccgaagaa gaacaggaac tgcaacgaat
    28801 caagaatgct ttagaggatt tttatattcc tgaaggagaa actttttcgg aaagtaagac
    28861 gg
//
LOCUS       DBGZHO010000030        27913 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.030, whole genome shotgun sequence.
ACCESSION   DBGZHO010000030 DBGZHO010000000
VERSION     DBGZHO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.030"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(18..716)
                     /locus_tag="ACN3HL_001537"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACN3HL_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACN3HL_001538"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACN3HL_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACN3HL_001539"
     CDS             complement(1147..1716)
                     /locus_tag="ACN3HL_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HHC8006418.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="ACN3HL_001540"
     CDS             complement(1790..3079)
                     /locus_tag="ACN3HL_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006419.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3406..4281
                     /locus_tag="ACN3HL_001541"
     CDS             3406..4281
                     /locus_tag="ACN3HL_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8006420.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4295..4618
                     /locus_tag="ACN3HL_001542"
     CDS             4295..4618
                     /locus_tag="ACN3HL_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006421.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4615..5367
                     /locus_tag="ACN3HL_001543"
     CDS             4615..5367
                     /locus_tag="ACN3HL_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HHC8006422.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5357..7528
                     /locus_tag="ACN3HL_001544"
                     /pseudo
     CDS             5357..7528
                     /locus_tag="ACN3HL_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACN3HL_001545"
     CDS             complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACN3HL_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HHC8006423.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9831..12017)
                     /locus_tag="ACN3HL_001546"
     CDS             complement(9831..12017)
                     /locus_tag="ACN3HL_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHC8006424.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACN3HL_001547"
     CDS             complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACN3HL_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HHC8006425.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12239..12679)
                     /locus_tag="ACN3HL_001548"
     CDS             complement(12239..12679)
                     /locus_tag="ACN3HL_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HHC8006426.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12753..13292)
                     /locus_tag="ACN3HL_001549"
     CDS             complement(12753..13292)
                     /locus_tag="ACN3HL_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HHC8006427.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13907..15373)
                     /locus_tag="ACN3HL_001550"
     CDS             complement(13907..15373)
                     /locus_tag="ACN3HL_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHC8006428.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15684..17765)
                     /locus_tag="ACN3HL_001551"
     CDS             complement(15684..17765)
                     /locus_tag="ACN3HL_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHC8006429.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(18289..18648)
                     /locus_tag="ACN3HL_001552"
     CDS             complement(18289..18648)
                     /locus_tag="ACN3HL_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HHC8006430.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18678..19019)
                     /locus_tag="ACN3HL_001553"
     CDS             complement(18678..19019)
                     /locus_tag="ACN3HL_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006431.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(19016..19690)
                     /locus_tag="ACN3HL_001554"
     CDS             complement(19016..19690)
                     /locus_tag="ACN3HL_001554"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HHC8006432.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACN3HL_001555"
     CDS             complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACN3HL_001555"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HHC8006433.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(22081..23271)
                     /locus_tag="ACN3HL_001556"
     CDS             complement(22081..23271)
                     /locus_tag="ACN3HL_001556"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHC8006434.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(23292..23819)
                     /locus_tag="ACN3HL_001557"
     CDS             complement(23292..23819)
                     /locus_tag="ACN3HL_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HHC8006435.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(23866..26655)
                     /locus_tag="ACN3HL_001558"
     CDS             complement(23866..26655)
                     /locus_tag="ACN3HL_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HHC8006436.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(26802..27002)
                     /locus_tag="ACN3HL_001559"
     CDS             complement(26802..27002)
                     /locus_tag="ACN3HL_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8006437.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(27454..27774)
                     /locus_tag="ACN3HL_001560"
     CDS             complement(27454..27774)
                     /locus_tag="ACN3HL_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006438.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7846 a         5918 c         4903 g         9246 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcatta gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctccctttct atttatttaa atacgcaaat
     3181 cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa aacgaatgta
     3241 ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc cattacaatg
     3301 aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat agaagaatcc
     3361 aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg caaacgttca
     3421 actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt cgaagatatt
     3481 cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca gggaaccttc
     3541 agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt ttccgtatac
     3601 aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac gatcttgttg
     3661 gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga agcaatggcc
     3721 gagaatcatg caacgatcga caacaataca taccctctag acaatcattt ttttgtctta
     3781 gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc acagctcgat
     3841 cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact tttgctactt
     3901 ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag ttatgaaata
     3961 gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc atcttatgcc
     4021 ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat cagtccacga
     4081 ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg gagaaattac
     4141 gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg cctgattttt
     4201 tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct tgttgcacaa
     4261 attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag attatttcat
     4321 taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg tattcaacaa
     4381 ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga gcttgatttc
     4441 attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac tcgtttatcg
     4501 caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt ctttacctct
     4561 ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga gattttgatt
     4621 cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag aggatgccat
     4681 gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag aaaaagtgca
     4741 aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat tcaagcagaa
     4801 aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag aggtcttgat
     4861 tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga ttggaaattg
     4921 tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga agaatgttct
     4981 cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct agacttgtat
     5041 ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt aggcaaccgc
     5101 gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc tggcgatgag
     5161 aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct ctttgttcct
     5221 gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg aacggcttat
     5281 cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat atgttcattg
     5341 ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg tttactcctt
     5401 tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc aaaacagcta
     5461 ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc ctaaaaaatg
     5521 ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat attttccttc
     5581 gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag aggaattctt
     5641 ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt ttctcataat
     5701 gttgctgatc tatttattta ttacattgac cgtggattac gactattggt acgcaccctt
     5761 tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag atttactgta
     5821 cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc aatttttctc
     5881 catccggttg ttgtcgggaa acactcgatt ccagtcattg actacagttc tgcttatttg
     5941 tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc aatctctcga
     6001 ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg acacactcca
     6061 tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg aacagcttgg
     6121 tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag gaaatggcta
     6181 ttggaagatc gaaaataaaa atcattacac cggttctgga tggatagaag atcaggacgc
     6241 acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa ccgttataga
     6301 agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt atccttatgg
     6361 aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact atttgcctga
     6421 aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt tacaaacaga
     6481 aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg atgatttaga
     6541 aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg aggacttggc
     6601 ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg tctaacagta
     6661 tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata ctccgaaaga
     6721 acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg acaacttttc
     6781 aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga caaaaggttt
     6841 tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca gcattctcaa
     6901 tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc ttccatttga
     6961 accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa caaccgaaac
     7021 cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa ctatttccag
     7081 tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt ataaaatcgt
     7141 cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt tattcagaaa
     7201 atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta ctaatacgat
     7261 tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac ccgcagaatc
     7321 tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc gtttcattcg
     7381 attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg taaaattcga
     7441 taaaaaaacc tatttagaaa taacgcgtat aataagaaaa acggtataca aaaaaattct
     7501 gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta cttctggaat
     7561 gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac acgttttttg
     7621 tcacaacctt ttttcattat tatttgattt tcaatgtcaa agcatttaga gctacaacta
     7681 ccgtacttaa cgacatcaag acagcaccaa ctgctggact taatatgata ccaattggcg
     7741 caagaattcc ggctgctagc ggaattgcaa gaatattgta acctgccccc caccagaggt
     7801 tctggatcat tttctttcgc gtttgcttgg ctagatcaag aaaatgcaaa atatcttttg
     7861 gatcgctgtt tgtcaatacg acatccgcag aatcgattgc gatatctgtc cctgcaccga
     7921 ttgccatccc gattgaagca cgggctaaac ttggcgcatc attgatccca tcacccacca
     7981 tgattacttt tttcccttgg tcaaggtatt tctggacaac agcttcttta tcatctggta
     8041 ataaaccgcc ataatattct tcgatcccta aataatctgc tactgcttgg gcagcgtttt
     8101 tattgtcacc agtaagcatg acaggagtga tttttctttc tttcaatgtt cggataaatt
     8161 cttttgcttc tgtttttact acgtcaccta aagcaacgat tgcagctaga tgattttcta
     8221 aaatcaggaa gctgatggta tttccttgtt cttggtaagg tttcaataat gcttgttcta
     8281 cgtttaatcc gagacgctca acttcttttt cattaactat tttcacttgt tgttttttga
     8341 ctgttgcctc tagcccgact cctgaaagat tttttagatt ttcagcttga taaggcttga
     8401 tttcatgttc tttcaaataa ttcataatgc caacagccaa tggatgattg gcattcgctt
     8461 ccaaggctcc tagatattga aggatttcat ttttattgaa cgcatcatca agtacttcga
     8521 cacccgttac agtaaatttt ccttctgtta gtgttcctgt tttgtccagc atgatcacat
     8581 ctagatcatt ggcttgctcc agtgcattgc ggtttttcaa aagtaatccg tttttagctg
     8641 ctattgatgt ggagcgagca acaactaatg ggatagctaa acctagagca tgaggacagg
     8701 cgatgataaa gactgttacc atacgttcta atgcattagg aagatctgtc aagaacaacc
     8761 aggcgatgaa tgccaggata cccacaatta atgcgacata aaacagccat tttgccactt
     8821 tgtcagataa tgactctagc ttggattttt ctccttgtgc ttttcgcacc atttccataa
     8881 ccttcgctag ataaccattt tcaccagttc cagttacttc gatttcgatc gttccatccc
     8941 cattgataga accgccaatc actttgtcat tggcttgttt tttgattcct cttgattcgc
     9001 cagtcacagc tgattcgtca acaattgttt cacctttcaa gattacacca tctgttggca
     9061 ttttatcacc agaccggacg atcaaacgat caccttcgtt tacttctttc aatgaaactg
     9121 tctcttcttt tccatctttc gtcaagcgtt tcactgattc tggcagtaat tctgctagtt
     9181 tttgtaaagc attgctggca ttcgacacag cattcatttc aatccagtga cctagtagca
     9241 taataacgat caaagtagcc aattcccaga agaaatccat gacgtgtgta tgtggattga
     9301 gcagatttgc gataaacgaa tagacactat aaatatatgc aactgtaatc cccatcgcga
     9361 tcagtgtcat catagcagga cttttttgtt tcaattccat cttagctcca cttaaaaatg
     9421 gctgaccgcc atagataaat agtatagttg ctaagatcaa tacgagccaa tcagaaccag
     9481 gaaacgttac ttgaaatgga aattccattc ccatcattgg tgaaaaaaga atgattggga
     9541 tagctaggat aagcgatagc caaaattttt gtttgaaatt ccccatgtgc atggaatgat
     9601 ccatgccgcc gtgttcgtga tccatgtgca tcgaatggtc catttgtttg ctgtttgcta
     9661 tatctccatg gttatgtccc atgtgcatgg aatgatccat ctgactatgg tcatgtttca
     9721 tctccatctg tttttcatga gattctgtac tttctttgtt tactacttct tttttatgct
     9781 catgtttttt ctccatatcg ttcccattca tttttactcc atcccttctc ttactttttc
     9841 atgtgtcgat ttaagctcag ggagttcaac aatacactga cggaactaaa cgccatcgct
     9901 cctcctgcaa tgattggatt caaaaagcct agtgcggcaa aaggaatacc aatcgtatta
     9961 tagacaaaag cccagaaaag attttgtttg atttttctca atgtcaacct agacaactcg
    10021 attgtttgtg caatggatgc caaactgcta ttcatcagcg tcacatcggc tgtttccatc
    10081 gcaatgtccg ttccacttcc cattgccata ccgacatcag ctaatgctaa ggccggtgca
    10141 tcattgattc catcgcctgc cataccgact tttttgccat ctttctgaag tttttctacg
    10201 taggctgctt tatcctctgg aagtacttca gcaaagatat gctttggatc aataccaact
    10261 tgtttaccaa tcgtttcggc tgccagtttg ttgtctcctg tcagcataaa aacatctaat
    10321 cctttattct ggagctgctt gattgcttgt ttggcttcta gtttgatttg atcagccacg
    10381 gcaatccacc cgatcacttg cttttcatca gctaaaaaca tgactgtttt tccctgctgt
    10441 tctaattcta acgcgtgttc ttggtattca tcaaatgata ggttcaattc aattaatcgt
    10501 ttacgtgtac ccgcaaaata gcgtactcca ttaatcgtac cgctgatccc agcacctggg
    10561 tgggctgtaa aatcaatcat atcgtatgtt gctgcttctt gcagttttcc gtattccacg
    10621 attgctttac ctagtggatg ttcagaagct tgttctaaag tataaaaaat agataggact
    10681 tcttttgaac cgactagatc tgtaactttg ggctttcctt ctgtaatcgt tccagtttta
    10741 tccaaaacaa tgctgtctaa gtgagcagct gcttctaatg cttctccgcc tttaattaaa
    10801 attccatttc gtgcaccaac acccgttcct accataatag ctgttggggt cgctaaacct
    10861 aatgcacatg gacacgcaat gactaataca gagacactat ggatcaatgc gagttgccaa
    10921 tcaccagtga tcaaacctgt agctatgagc gtgataaacg cgatgactaa tacgatcgga
    10981 acaaaaatcc ctgagatccg atctgcgatt ttttggattg gggctttgct cccttgagca
    11041 tcttccacca tttgaatgat ttgcgctaat actgtctgct tgccgacttg tgtgacttcc
    11101 atgtgtagca gaccattcgt attgattgtc ccgccaaaaa gcgtgtcatc cggattcttt
    11161 tctacaggaa gattttcacc agtaagcata ctttcatcta tcgcactgct tcctgaaata
    11221 attcgaccat ctgctggaat ctgctcacca ggacggatga ctagttgatc accaacgact
    11281 acttcttcaa tcgctaacgt ttcttctttc ccgtttctta tcacttgggc ggtttttgtt
    11341 tgaagagaca tcaattgttt gattgcatta cctgttttcg tttttgctgt atgttccaaa
    11401 tatttgccga gcaaaatcag cgtgatgatc atactgctgc tttcaaaata aagatcttgg
    11461 gggtgtccac ggaaaaatcc gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt
    11521 gctaccaata catccatatt tggtgctttc gtcttgattg catggtacgc acctttataa
    11581 aaacgagcac cgacataaaa ttggacagga gcagacagca ctaactggac gattggaaaa
    11641 tgaaaaaagt gaacaatcgc cgcatggctt cctaacatca tagcaatcat tgacaacatc
    11701 aacggcaaag tcaaaaccgt actcaatata agatcgaata gcattttttt caaatacgct
    11761 tgcttttctt ctgcaatttt ttgtttgtgg gcttcatcgt acaaaattgc accataaccg
    11821 atgttttcta cgctttggat taatttttca gtggtcgtcc cttcatattt gacacttgct
    11881 ttttcagtgg ccaagttgac tgtggcattg accacaccag gttgtccgtt cagctctttt
    11941 tcgatcctag cagaacaatt tgcacaagtc atacctgtaa tgacgaacgt atccattttg
    12001 gtttctgctg ttgccatcaa atcacctctg ctttataacc caatccattg attgcttgac
    12061 aaatcttttc ggattgaact tttgtttcat caaacttgac cgtaccgttt gcttttttca
    12121 aatttacttt cactttttgc acgccgtcaa gtgcgcttac tgtttcttct actcttgctg
    12181 cacaatgatt gcagctcata ccttcgattg aaaattgttg tttcattttt tcttcctcct
    12241 attgatgttg tttacattca cattgacctg ggatacagtt acattcgatc gtatctactg
    12301 gttgcttttg ttccagttgt ttcaaaatct cattgatatc ttcttgagtc aaagtggctt
    12361 cttctactag atccgcaatc gtctctccaa tcctttttgc acagatatgg gaaaaaagat
    12421 tttccgtcgc actgcgaact gtttccatct ccgagacagc tggatgataa atgaattttt
    12481 ttccttcttg ttctgtccag atcacttctt tttttaccaa acgtcccagc aaagttttga
    12541 tcgttgctgg tttccaatcc atcgaatcag ctaagatctg cgtgatttct tgggctgtcg
    12601 tctgtccaag tgtccaaata acacgcatga tctcccactc tgaatcactg atctttactg
    12661 gcgttttgac tttttccatt tatttcacac ctttcgttta caaatgtaat cattagctta
    12721 tgaatacaga ttacgcttgt aaacaaaaac tgtcaattat ttttgctctc tattttcaat
    12781 ttagttaaaa attcttgttt ctctcgtctt gttttaagga tgatcagttt atttcttgca
    12841 ttagctactt ggatcagctg ctgtattttc ggttcattgt tttcttcaaa atgccagata
    12901 aaagataaaa attctaagta ttccctgttt agtttctctg aaaatgattc aggcatatct
    12961 ggccgagatt ttttgtttat ctttcttttt agagaacgcc aaactactcg gtagatggcg
    13021 agataacgcg gcactttaag ccaaatgatc ttatctgctt ctttaatcct ttcctctaat
    13081 gtagaagtat aatttccttc aacaatccat gacggattag ataccataaa cgattgctgt
    13141 tcttgcaaaa accacttttt tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct
    13201 agcggcagta gcggaaagtc ggtgatttct ttgatcttcc ttgcgagggt cgattttccc
    13261 gacccacttt gtccaatcac gatgatcttc attcttctcc ctcacttctc tttggaattt
    13321 ggttcgatca taccacttat aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt
    13381 caaagtccct tgtttcgaat aaatggtgtt caatcagctg accttcagca ttaactcaaa
    13441 aaacggcaaa atatgaggag ctattttttc gtttgttcct ctaatactca ggtcaaatcg
    13501 ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aacacctcgg tcacaaggca
    13561 caatagtcaa caaacatgag aagttgtttt ttgaaattgc tccttgtgac tcggagttaa
    13621 acggcaggct cactacctct ttcttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    13681 gcccagcaaa acgaaaaata tgaggggcta tttttgtttg gctgttctta ttacttgatg
    13741 caggacagct ttttcacaac ctctgattca cggtgttcca gaagtagctt ctgcgaaaaa
    13801 caagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    13861 aagctgacca cttctgtcac aacctcttgt aacaagtatt tctattttaa ggctgaacca
    13921 ctgtttctgg ttcagtgatt tctttgtttt tgtctcgacg agcaattgct ggcaagatca
    13981 tacctaataa gatcaagaca attggtgtga tgatattcgt gaataattgg aaccaccatg
    14041 ctttaggatc agcagtataa tctacttttg gcaccattcc taggatacat gcaaacgcag
    14101 tgaaggcaaa gcaccaagca ccaaagataa aaccgatttt tggattttta acaaatttat
    14161 attcagaatt gaatttctta taagctttat tcaacatcat atatgccaag aacacccata
    14221 ggtaacgcat tggcatgaca actgagttca agttcgtcaa ccattttact aattcattca
    14281 tatctttgat accaaagatc ggcaacaaaa taatgattcc tactagtata cctgtcagaa
    14341 gataaccatt caccaatgta cctttacgat tacgtttacg tagccagttt ggtacaaatt
    14401 ctggatccgc atctgctaac aagattttta gtggtgcatc aattgaaaag gctaatgcgg
    14461 agatttgtcc aatcatgttt gtcaatgcgt aaatgatcat caatgagtta ccgataccat
    14521 agtaattacc taaaatttga aaagcactgt atgccccatt tgccatcaag tctttaggaa
    14581 tattatcgct agcaaacagc atacccattg cgactgagcc taatacagca caaatcccta
    14641 ccattgctgc taagaagatc atccctttag gaaattcctt tgcaggattt cttgtagagt
    14701 tgacataagg ggatattttt tccgctcctc caactgcaaa tactagcatc gaaacggttg
    14761 tgaaataact gaaatcaaat gttggaatat atgttttcac ttgattcata tgtggtgtgg
    14821 caaattccat cgttggattg atgaacggtg ccgttacagc taaaagaata aataagatcg
    14881 acatgacgaa catcgctgtt ccggccagtc cgccaatcac tttcaaagta gaaagtcctt
    14941 ttgttgataa atataaaaag gcaagaaata taataagtga aataactgct accatttgta
    15001 ctgacatcgt atttacgata tttccatttc cttggactgc ccaaccgcca gcaatcagga
    15061 ttgcttgagg cttttgtgcc aaataaggaa tatggacgac ccagtaagtc caagcggcat
    15121 agtatgccag tcgtttatta gatgtcgtat tttcgaccca tgaactgacg cctcctttac
    15181 tatccttgaa ggctgaccct aattgtccaa cgatcaatgc gtatggaata aaataaatgg
    15241 ccaaaatcaa tagccaagag gtgacaactg atactccttg ctgagcatag ttattaacta
    15301 cattccccat gccccaaacc atgttaaatg caattaacgc aacagtaaac cagcgtaatt
    15361 gtttgttgtt cattcgttct ctcctttatg ataaaaattt gttatccaga tgtaatcata
    15421 ttcaattttt aacaaactta caagacagtg ttattttatg tgtgtattct tttatttaat
    15481 acacatcgtt ttttcatatt ttttccatca aaaaaataag ttattttctt ttatttcatt
    15541 taccttattg aatttcaagc tattttgaat tttctgcaaa attaaaaaca ttagttattt
    15601 tataatccta tctattttct ttacattttt cattaagaaa aggatataaa aaaaagagga
    15661 cgttcattcg tcctcttcat tgatcaacgt ttatttttta catgcaagct tcgcatggca
    15721 ttcaaaacag ctaatactgt caccccaaca tctgcaaata ctgcatctcc cattgatgca
    15781 aaaccaaaag cacctaaggc aagtaccaaa atttttatcc caatagcaaa gacaatgttc
    15841 tgtttgacga ttttcaatgt tttctttgct aaatggattg cttctgcaat cttcgatggt
    15901 tgatcattca tgatgactac atctgctgct tcaattgcag catcgcttcc caatccaccc
    15961 attgcgattc ctacatctgc tcttgctagc accggtgcat cgttgattcc atctccgaca
    16021 aatgcggtct ttttattgtt tctttgtaag atttcctcta accgctgcac tttatcttct
    16081 ggaagcaatt cgctatatat cttgtccacg cctacttgct tcccgatatg atcagcaatt
    16141 tttttcgaat cgcccgtcaa catgactgtg ttcttcacac cagccttttt taattgaacc
    16201 aatgcgtcta cggcatcttc tttcaaggta tctgcaataa caagataacc actgtaactt
    16261 tgatcgatcg ctagataaag caatgtaccg atttcttgac ttgaaggaaa agagatttca
    16321 aatctttcca tcaatttgtg attacctgct aatacttgtt tgccatcaac ttcagctaag
    16381 atcccttcac ctgcaaattc ttggatatta gctgttggta aaagcggacc tgcgtagcct
    16441 tctaaaacag attgagcaat cggatgtgta gaaaactgtt ctgcactcgc aacatattgc
    16501 atgaatatct ttggatcgat ttttgtatcg atcgtctgga tcgaaaagtc acctttcgtt
    16561 aatgtgccgg ttttatcgaa taccactgtc tcagtttgtg caagcaactc caagtaattt
    16621 gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa gaaactaagg
    16681 ggtacggaga tcactaatgc acatggacat gagatcacta aaaatgtcaa tgctcgatag
    16741 atccattcag aaaacgccgc tccagaaaca acaagtggag gtaaaacagc taataaaacg
    16801 gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa attttcagct
    16861 ggtgcttttt tactgctggc attttctact aattctaata atttgctgat agtagaattt
    16921 tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa tccacttaat
    16981 actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc tgacgtatcg
    17041 actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc aggcttcaca
    17101 agtacaaact gaccgatctg cacgtcttca gggttcacgg tcatcaatcc ttccgtcgtc
    17161 tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt tcttgaatga
    17221 ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac tgctacggct
    17281 tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag aaaattctca
    17341 tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc atatcctatc
    17401 agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc aaataatagc
    17461 aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct ctctttttca
    17521 tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc tggttctaat
    17581 tccttcacta ctttttttat ttcttgttca atcgtagcca aatgatcttc ctctgcgtca
    17641 atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt gatcttctga
    17701 actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa tctgtaactt
    17761 ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact aattataaat
    17821 gaacggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc tgcatcggaa
    17881 aatttcttcc atacagatgt tttggcttat tctttctttt tcttttcgat cattgccact
    17941 gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact aagtttgaag
    18001 cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata tcttttttca
    18061 atccctgcaa aatgtccttc ccagatattc gaagctccac tacgctttca aaaatataga
    18121 aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca tataaataaa
    18181 agacgtaaaa gtcacatgga agaacttata caggagaacg catagagtca ggtgaaatac
    18241 atgtatccca cctgactcta tgctttatct aacctttatt attctctttt atacaatttc
    18301 tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg caaaaggtat
    18361 ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag caattggtag
    18421 gcctgaaacg atcagccaga tgatattaac aatcaatgac atgccagact ggtgataaat
    18481 tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt gcataccgat
    18541 tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc taagaccacc
    18601 gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg tatttctcct
    18661 tctattactg tttttgatta aaactgggca aaaaatgatt ttattcttct ttttttagct
    18721 tccagtatca aatattctgc aaattttttt tggatttctt ccgtattttc ttttgttact
    18781 aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc tgactgttgc
    18841 acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac gagcaatagt
    18901 ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc tggatgatca
    18961 gtaatcagct gattgatttg aggtagatct tcttttactg cccaccgtat ttccatcatt
    19021 tctcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg gcaattgcat
    19081 ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc ccatcttctc
    19141 ttgtatattt cgaaaaacca taaacaatcc ctaaagcatt gaatatacca tctaaaggaa
    19201 ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta gggtctaagt
    19261 ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc atcaagatga
    19321 tgttgcagat tcccactgtt tgaagttcat ttagtaattt tcgataaacg gattcaaatt
    19381 gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc caggtatcat
    19441 tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct tcttgccagc
    19501 gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat tcaaattcca
    19561 tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct ttacctagat
    19621 cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct atcaccgata aataatatac
    19681 gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt ccttatatta
    19741 tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga caccagccta
    19801 gtcccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg ctattttttt
    19861 cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga tcgatcacac
    19921 ctaagcttcc gtcaatcaga ccactgatga cgccatcaga acatatattt ataggctcat
    19981 ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt gggatagatt
    20041 ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca tatggattat
    20101 tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt tgttttcagg
    20161 tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt ccatttgaat
    20221 taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg tgaatcaaat
    20281 agcaatttct tttgctttct tctcttgtct gctggaaact tcctttatcc cgtattttaa
    20341 aaaaagaact gcgagagttc gcagttcttt tttagaataa acggtgctct ccggccaact
    20401 cctcggtcac aagtcacaat agtcatcaaa catgaaaaac tgttttttga aattactcct
    20461 tgtgactcgg agctgaacgg caggcgcaca acctcttcct taaacggtgt tcaaaagcca
    20521 gtttctcggt attaagccaa atttatgcaa aaatgtggaa agccatttcc acaaaatttt
    20581 tcttaatact cgaaactaaa cagctttttc acaacctctc cactaaacgg tattcaaaag
    20641 cttacatctg cggtaataag tcccgccaat tcaaaaacat gaacagctgt ttttgcttgg
    20701 ctgttctaat tacttgatgc agaacagctt tttcatcacc tcttatggat aaattcggtt
    20761 caacaaacgt gggaatggaa tagcttcacg tacatggtcg ataccagcaa tccaagtgac
    20821 tgttcgttca agacctagac caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc
    20881 aagataccat gaatattctt tttcatccaa accgtgatta cggatttgtt ctagcaagaa
    20941 atcatagtct gttgcccgtt cgcttccgcc aataatttca ccgtaacctt ctggtgcgat
    21001 catatctgca cagatcacca cgtcttctct tgttggatgt ggtttcatgt agaatggctt
    21061 gatggctttt ggatagttta ggataaagac aggctgttcg aatgaattcg caatgaacgt
    21121 ttcatgaggt gaaccaaagt cttcgcccca ttcgatgtca tcaaatccat ttttcttcag
    21181 taattcgatc gcatcatcat aagtaatacg agggaatggc aattttgtat aagtttttaa
    21241 gacttctttg tctcgtccta gtacatctaa tgcatattcg caatgatcta aaacattttg
    21301 tactaagaat gctacatatt gttcctgtac ttctaaactt tcttcttgat gagtgaaagc
    21361 catttctggt tcgatcatcc agaattcgat caaatgacgt cgtgtttttg atttttcagc
    21421 acggaaagtc ggaccgaatg aaaagacttt tccgaaagcc atagcagcag cttccatgta
    21481 taattggcca ctttgagata aataagcttt ttgatcaaag taatttgttt cgaatagatc
    21541 cgtagtgcct tctggtgcag aaccagtcaa gatcggcgga tcaattttga caaaatgatg
    21601 ttgattaaag aattcatacg ttgcacgaat gatttcattt ctgatctgca taatcgcatg
    21661 ttgtcttgaa gaacgcagcc ataaatgacg atgatccatc aagaagtctg ttccgtgttc
    21721 ttttggtgtg atcggataat cgtggctctc gcttaccact tccacatttg taattccgat
    21781 ttcataacca aattttgaac gactgtcttc acggatttct ccagttacta acacggatgt
    21841 ttcttggtgt agatttttag ctgtttggaa aacttcttcc gacacttcgc tttttacaac
    21901 tacaccttgg aaaaaggctg ttccgtctct taattgtaaa aatgcgattt ttccgcttga
    21961 tcgcttattt gcgacccaag cgccgattgt tactgtttct cccacatggt ttttcgaatc
    22021 gatgatttga atttgttcca cgtatgactc tccttttata ttccttgaat ttctttagga
    22081 ttaattttga cttttactct caataaattg cttgattctg cgtaccgctt cttctaacgt
    22141 agcgcgatca gtagcataac tcatgcggac attttctggt gccccaaagc cttcgccagt
    22201 cacaagcgct acccctgttt cttctaaaag atcttctacc cattgtgtga cattttcata
    22261 tttacacatg cgtagcgttt cttttacatt aggaaaaaga taaaaagctc cttgtggctt
    22321 ttcaagagaa acacccggca gttctgccac aagcgaatat aacgtattca ggcgttcttc
    22381 aaaggcgttc cgcatttctt ccactgtatc ttgctcgcct ttcaatgctt caacagctgc
    22441 atattgactg actgctgtcg gattactggt tgactgggaa gcaacagcga tcattccatt
    22501 gatgatcaca ggatttccca ccgcataacc aatgcgccag cctgtcatcg catatgtttt
    22561 agacacgccg ttgatgatga tagtctgatt tttgattgct tctgaaatcg ttgcaattgg
    22621 agtaaactca ttgccattat aaactaaacg accataaata tcatcagcaa ctatcaaaat
    22681 atcatttttt actgcccatt caccgattgc ctgcagttca ttcttgctat aaatcattcc
    22741 agtcggattc gatggagaat tgatgattac ggcttttgtt ttttctgaac gtgcttgttc
    22801 tagctgttca acagtaactt tccagctatt ggattcttcc cctttcacaa agacaggaag
    22861 tccttctgcc agttttactt gctcaccgta actgacccag taaggcacag gaatgatgac
    22921 ttcatcttgc gggtcaagga tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc
    22981 tgttacgact gtttgtgaag gttcatagac aagtccatag tttttcttca gataatcaac
    23041 gattgcctgt cgaagctctg ggattcctgc tgttggtgta taatagctag ctttcccgtt
    23101 gcggattgct tcgattgctg cttcttggat gttttctggt gtcgcaaaat ccggttctcc
    23161 cacagtcaaa ctcagcacat ctctgccttt tgcttttaat gccttggcct ttgccgcagc
    23221 tgccaaagtg acagacggtt ctaatcgttt tgttcttttt gataactcca tcccattcat
    23281 tcctttacct tttaaattcc cttgattgtc ttgacttcat ctccagattc aaagccaatc
    23341 aggtaataat tcagtttccc atttgtttct tttcctacta cttcccacac aggctgatca
    23401 tcatacatcc ctaaagcagc tttttcgatt tggatttcag gatgggccgc agcaattgtc
    23461 tgttttgctt cgttttcagt cagtcccttt gtttgatcca atacttttac tttttcacca
    23521 gatttaggaa tgataacggc gatttctttt cctttatcat ttgtacctgt cagtgaaaag
    23581 tatgtcttct ttcgagtaaa ccaataaaaa tgatcggctt cctcaagatt tgcatatttc
    23641 tttgcgattt ctactgcttc tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa
    23701 aaaatcgagc tgatcacgat gaccgctaat aaaaatacga tcaagccaag taacacgcga
    23761 ttaatcgttt tttcctttgt ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt
    23821 ccttttcatt atagcagatt ttaattatga aaaaagacag ctcctctaac ttccttcttc
    23881 atttttcttt aagaattcat ggatgtcctg atagatttcc tccatagcta gctctttgat
    23941 cggtactttt ttcggtaatg catggatgat ccgtgcacca tattttgcag tgactagtct
    24001 tcgatccaaa ataagcaata cgccacgatc tgtctccgtc cttatcaagc gacctaatgc
    24061 ttggcgtaac ttcaaagctg ctttaggtac ggattcctgg taaaaaggat tgatcccctc
    24121 tgattctaaa taagcgttcc tagctttgac catcgggcga agcggattat cgaagggtaa
    24181 acgtgtgact acaacgatct gcaaagcatc cccaggcaaa tctacacctt cccaaaagct
    24241 gtcagcgcca aacaatacgc ttttttctga caaaatgaag cgtttcaaaa gcttctcccg
    24301 gcttccgcca aacccttgag ctagtatttc tcgtcctttt tctagcatag acagatgcat
    24361 tttctgatag accttctgca aaacatcatg agaagtgaat aacacaagta ttggccgatc
    24421 ttcttgttcg atcagacctg taagtgctgt ctctaaataa tcgatatatg cttgattgct
    24481 gacttgatgg acggcaggtg cctcttttgg cacatagatc cttgcctgtt tctcataatc
    24541 ataaggagag gcaatcactt taagaggtgc tgcttcaatg ccaagccgct tagagagata
    24601 gtgtcgatta gggccgatct tcagcgttcc tccaatataa agaatacgat catatcgagg
    24661 ataccaaaca gtcgacggca acatagccgc ttgaaaatca tggagatgaa aaatcatctg
    24721 ctgcgctgtg ttcccaggaa cgaaccaatg gatcaaatga tctcgccagt cttccagcca
    24781 ttgatccatc agcaagtact gcttgtctaa ttgatcaaat aagctatata aacttgctaa
    24841 atcgatccgc atctggtttg tccagctttc ttggataatc tcaaaagtca gacgcatttg
    24901 tgactgtagc tgctggatct cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga
    24961 ttccagtggc agctgatcca acatctcttt tgtcatcatg acttcttctg gatactgtcc
    25021 gttaggttgc ttgccgctca ctaaactcat taatccttct gccatacaaa tctgtgcttc
    25081 gcatagcgca gaaagttctt ctcgataaat cgataaccag cgtaaggctt catgttcttt
    25141 cggtaaatag ctttgtattc ggtcaaacag ctgatttggt tcttctaatt gctggatttg
    25201 tttatggaaa tagttaatac ttaatcgttt gtcatttact ttttcagcga tttccggcaa
    25261 atgatgtact tcatcgatca acaaaaatgg actagctgga agcaatggtt cttttcgctg
    25321 tgtttcttgt attaaaaacg catgattgac aatcaaaaaa ttactttgcc tgattttctt
    25381 ttgcaagaaa cgaacaaagt cttgttcgta aaatgactga tttcttgcta aaaatccaat
    25441 acctctgtgc gcgatatctg caaagaatga atggttcaaa tttgttaaat gtaattcatc
    25501 caaatcaccg gtcttcgttt gcgtcagcca aactaagacc gccatttgat acaaagcata
    25561 ttgtttttgt tctggcggtt ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg
    25621 gcgatagctt ttgataatta caggttgtat gggctgatct agcaattgat tcagcaatgg
    25681 aatgtctttt tctatgatct gctgctgcaa aactagcgaa acggtactga tgacagcggg
    25741 tttttcaggt gtagccaaat aactcaatgg cagcagataa ccgattgttt tacccattcc
    25801 tgtagctgct tcgatcatca aatcttttga ttcatctttt gtgaaatggt cgtagaccgc
    25861 attcatcagt ctgttctgtt cttttcgata catcagtgtt ttaccaaaca ttttttcttt
    25921 tgcttgtttt tttcttggat atgtccgctc gccataatgg acggatgtga atagttccac
    25981 ttcttttttc tgcaaagcta gcccatcgac gatttctaat gagggatcaa gtggctctgg
    26041 tttttctttc atttcttcaa tcacatgata aatgaaacga ctcgtatcca tacctgtgtg
    26101 tctacttaat cgcgcaatct gctctaacgt gatgattggc aattttctca tccgttcttc
    26161 gatcagcaaa agaagttgac ccgtcacttc ggcatcacta tctgcctgat gaggattctc
    26221 atgaataaat ccaaggcttt ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa
    26281 gaaaatttgt gcaagttcta ctgtatcgat gcctggtatc ttcaaactag gaagtccgca
    26341 tcgcatgagt tcatggttca aaaaattata atcaaaataa atattatgcg cgacaaatat
    26401 ggtgtctgcc aaaagattgt aaatcgtttg ggcgacatct tcgaaataag gcgctttttg
    26461 gacgcgttga ttcgtgatcc ctgttaaatg ctggatttgt tttgaaatct tccgccctgg
    26521 atgaatatcg atcgaaaaac gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa
    26581 ttggatgatc cgatcttctt ttggattcgt cccagtcgtt tcgatatcaa cgactgcata
    26641 agttcttggt ttcaaaatat cttcctcttc tcctgcctct aatgttcttt tgaaattata
    26701 ctacaaagtg cagaaaaata ctctcatcgc tttttaaaga aaatagacaa aaacgcccag
    26761 acacgcaaat gtctgggcgt ttatttttta gtataggtta attaagcttt agtaacgttt
    26821 gttgcttgag gtccgcgttg gccttcttca acatcgaaag ttactgcttg gccttcttct
    26881 aaagttttga atccgtcgcc ttggatagct gagaaatgaa cgaatacatc gtttccgttt
    26941 tctgcagtga tgaatccaaa tcctttttct gagttaaacc attttactgt acctgtttcc
    27001 ataataaaaa tcctccttgt gtatcaacac atattttgca attacttgaa tggtgtatat
    27061 ctggaagatg tttatttgaa acaagctacc acagattacc gaacaaaaac tactcctata
    27121 gtatatcata ccgtttacaa aaaagctaga gtttttcgac tttttttatt aaaaaaagtt
    27181 ttctcagcga ttacataaag tgaaaaaccg aacttttttt aaaataaacg acatattgtt
    27241 cagttggtgt ttttttgctc tgatgttctt ctttaaacta aaaaaattat tctttctgac
    27301 tacttatcgg ttctgtttca acggtcgagg ctggggaaga ttctttagta ggtctgatgt
    27361 tctcatggta tttctgatag cctatgacag ttaccagaag aacaaggcaa accaatacga
    27421 tcaacgagat tagtttttct tttttgctca tatctatacc tcataaataa caggatgatg
    27481 tccatcatat ttctgagtat gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg
    27541 ccagcaactt tcataatcac aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa
    27601 agaccgttct tctgtttcag gaatcgcaga atcaagatct gttgtctgta cataaacatt
    27661 tttgtacaga cgtgtgcctg taataggaga ccgctgtgtt tcttcagcaa aaactggctg
    27721 acttgttaaa cttagggata gaaacagcaa acaccataac agtctttttt tcataaagac
    27781 ctccttatcg ataagttttt cccaattaaa atcatatctc aagaacgccc gttattcaca
    27841 ttttgttcat aaatgatgtt ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc
    27901 acaacctctt ttt
//
LOCUS       DBGZHO010000031        27635 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.031, whole genome shotgun sequence.
ACCESSION   DBGZHO010000031 DBGZHO010000000
VERSION     DBGZHO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.031"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(18..293)
                     /locus_tag="ACN3HL_001561"
     CDS             complement(18..293)
                     /locus_tag="ACN3HL_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006439.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="ACN3HL_001562"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="ACN3HL_001562"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HHC8006440.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACN3HL_001563"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACN3HL_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HHC8006441.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3399..6065
                     /locus_tag="ACN3HL_001564"
     CDS             3399..6065
                     /locus_tag="ACN3HL_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHC8006442.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6429..7181
                     /locus_tag="ACN3HL_001565"
     CDS             6429..7181
                     /locus_tag="ACN3HL_001565"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8006443.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7203..8357)
                     /locus_tag="ACN3HL_001566"
     CDS             complement(7203..8357)
                     /locus_tag="ACN3HL_001566"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HHC8006444.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8542..10983
                     /locus_tag="ACN3HL_001567"
     CDS             8542..10983
                     /locus_tag="ACN3HL_001567"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HHC8006445.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11313..12017)
                     /locus_tag="ACN3HL_001568"
     CDS             complement(11313..12017)
                     /locus_tag="ACN3HL_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006446.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12204..12449)
                     /locus_tag="ACN3HL_001569"
     CDS             complement(12204..12449)
                     /locus_tag="ACN3HL_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006447.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12466..13317)
                     /locus_tag="ACN3HL_001570"
     CDS             complement(12466..13317)
                     /locus_tag="ACN3HL_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HHC8006448.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13483..14487
                     /locus_tag="ACN3HL_001571"
     CDS             13483..14487
                     /locus_tag="ACN3HL_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HHC8006449.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(14728..15084)
                     /locus_tag="ACN3HL_001572"
     CDS             complement(14728..15084)
                     /locus_tag="ACN3HL_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HHC8006450.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            15452..16639
                     /gene="tuf"
                     /locus_tag="ACN3HL_001573"
     CDS             15452..16639
                     /gene="tuf"
                     /locus_tag="ACN3HL_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HHC8006451.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(16827..19418)
                     /gene="mprF"
                     /locus_tag="ACN3HL_001574"
     CDS             complement(16827..19418)
                     /gene="mprF"
                     /locus_tag="ACN3HL_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HHC8006452.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19444..20205)
                     /locus_tag="ACN3HL_001575"
     CDS             complement(19444..20205)
                     /locus_tag="ACN3HL_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8006453.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            20372..21004
                     /locus_tag="ACN3HL_001576"
     CDS             20372..21004
                     /locus_tag="ACN3HL_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HHC8006454.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            21063..21923
                     /locus_tag="ACN3HL_001577"
     CDS             21063..21923
                     /locus_tag="ACN3HL_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HHC8006455.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            22108..24423
                     /locus_tag="ACN3HL_001578"
     CDS             22108..24423
                     /locus_tag="ACN3HL_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHC8006456.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            24605..26446
                     /gene="dnaG"
                     /locus_tag="ACN3HL_001579"
     CDS             24605..26446
                     /gene="dnaG"
                     /locus_tag="ACN3HL_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HHC8006457.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            26470..27579
                     /gene="rpoD"
                     /locus_tag="ACN3HL_001580"
     CDS             26470..27579
                     /gene="rpoD"
                     /locus_tag="ACN3HL_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HHC8006458.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT         8937 a         4886 c         5763 g         8049 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta tgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttgaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt ttttttcaga
     3361 caggactagg gccaagatca aaaaatgggg gatgaaattt ggaaaacaag gaacaagcac
     3421 aacaagcggt ctataaagaa acgatcgact cgttgatgca gcaaacgcag agctcaaccg
     3481 atggattgag caccacgcaa gcgaaggaaa aattagaaag agatggcttg aaccagctaa
     3541 aagaaaagcc gaagaagcca acttggaaat tgttcttaga aactttcaaa gatgcaatgg
     3601 ttatcgtatt gctgattgtc gcactgattc agatggtcat gggtgactac atcgaattct
     3661 tagttatttt tgcagtattg atgttgaatt ctataatcag tgttgtccaa acaaaaaaag
     3721 cagaaggttc tttagaagcg ttgaaaaacc tttcagcgcc cgatgctcga gtgattcgtg
     3781 atggtaagga aaaaacgatt ccggcaaacg aacttgtggt aggagatatc gtgttgttag
     3841 acgcaggcga ttatgtacct gctgatggac gtttactaga tgcgggatca ttaaaagtag
     3901 atgaaggtat gctgacagga gagtcgactt ctgcagaaaa agaagtaacg gatatcacaa
     3961 gtacggtacc aatcggagat cgtacaaata tggtattcag tggaacgatc gtaacttacg
     4021 gacgcggtaa attcttagtg acttcaactg ggaataatac ggagatcgga caagttgctg
     4081 gccttttgga atcaacaact gagcaagtca ctccgttaca acgaggtctg gataaattca
     4141 gtaaaaaact aagtctggct attttggcat tgtctttatt gattttaggt atccaactgt
     4201 ttcgtattta tcttggagaa ggtacaggag atatgactgc agatatcgtc agcgcagtga
     4261 tgtttgccgt agccgtagcc gtagctgcta ttccagaagc attacagtct atcgtaacaa
     4321 tcgtgttatc tttgggaacg aataaaatgg caaaacgtca tgccattatt cggaagcttc
     4381 cagcagttga aacacttggt tcgacaagta tcatctgtac agataagact ggtacattga
     4441 cacaaaacaa aatgacagtt gttgactact ttttaggtaa tggcgatact ggggatttca
     4501 caaatgaccc ttcaaaatgg acagctgacg aacgtcgctt gatcgaaatc agtgttttag
     4561 cgaatgatgc atcgatcagt gaagacggta ctaaattggg cgaccctacg gaagtagcgt
     4621 ttatcgactt tagtgaaaaa ttaaaccagc cttatcagga aatccgaaac aactacccaa
     4681 gacaagcaga acttcctttc gattctgatc gaaaattaat gtctactgga cacacgatcg
     4741 ataacgaaaa ttacttgttt gtcaaaggcg gaccagatat cgtcttccaa cgcagtaaaa
     4801 aagtattgct aaatggtgaa gtcgttccga tgacggatga attgatgaaa aaattccaag
     4861 agcaaaatga agctttttca acacgcgcat tacgtgtact agcttttgct taccgtccac
     4921 ttgataattt tgatttatca tttgaagatg aagacgattt gatccttgtt ggtttgcttg
     4981 ctatgatcga tcctccacgt gctgaagtga ctcaggcggt aacagaagca agaagtgcag
     5041 gaatcaaaac aatcatgatt actggtgacc acaaaacaac agctgttgct atcgcaaaac
     5101 aaatcgggat ttttgaagaa ggaaacctgg ctttgaccgg gacggaacta gatgaattga
     5161 cagaagatca actaaacgaa gttttagaaa aagtcactgt ttatgcacgt gtttcacctg
     5221 agaataaaat tcgtatcgtt cgtgcttggc aaaataaagg tcatatctca gctatgacag
     5281 gtgatggtgt aaatgacgca ccagcattga aacaagcaga catcggaatt gctatgggaa
     5341 cgggtacaga tgtggcaaaa gatgcagcag cgatggtatt gacggatgat aactttgctt
     5401 ctattgtcag cgcagtagaa gtaggacgta atgtgtttga taatatcaag aaagctattt
     5461 cttatctatt tgcaggaaat ttaggtgcga tcattgcgat catctttgcc ttagttgctg
     5521 actggtccaa tccatttaca gcattacaac tgttgttcat caatttagtc aatgattcac
     5581 tgccagcaat tgcattaggt acagaaaaag ctgaacctgc tacgatgaac cgcccgccaa
     5641 gagatccaaa ttcaggaatc tttacggaca aaacattgat ttctgtaacg tatcgtggtg
     5701 tgctgattgg gattgctgtt atctttgctc aatggcttgg catgcagcat tcacctgaat
     5761 tcggtgtagc catgtcattt tcaacattga tttggtgtcg gacattgcaa acattcccag
     5821 cacgttcaaa cacacaaaca gctatccaag cagggttctt ctctaacaga agtgtcttac
     5881 tagctgtagt tgtatgtagc gcgctttact gcttaacaat gatcccagga ctgaaagaag
     5941 tcttctctat cccatcagca tttggattga cagaagtctt tacatgtatg ggaatcgcac
     6001 ttgtgacaat tgttttgatg gaaatcacta aattgatcat tgtacgagta caaggaaata
     6061 aataaaacga atcaacgagg ttgtgagcct gccgtttaat tctgagtcac aaggtgcaat
     6121 ttcaacaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgaa gagttggcag
     6181 gagaacaccg tttaaggaag aagttgtaaa atcagcattt tgagctaata ctgagggtca
     6241 tctgattgga cactgtttat tcggaaagag ggactttgac acgactttgg tcacagtccc
     6301 tttttttatt tatgatagac ggaaagccaa tcattttatt attcatcaaa agagatagaa
     6361 tagataaaag aggagaataa tttattccga aaagtgaaaa catataacaa aaaattagag
     6421 gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga agaatattat gaaatccagc
     6481 aagaatcgca agtaactatt gctgaagatg taaaaaatta tctgaaaacg gagaaagtcc
     6541 tgcctgctga aacagcagca gacgttgctg gaggatctgg cagatttctt tccttagcaa
     6601 aagaaattaa tcgctatgat ttgatcgatt tttcttcagg aatgctagaa aatgcaaaaa
     6661 aagaagcaga aaaaaatgag ttgccaaatg tttcctttat caaacagtcg ttagaagaat
     6721 ttatccaatc aaatgagaca tatgaaatgg tttttacagc agcaaatcca gcattggtac
     6781 atcttattca attagaaaaa ttgatgaaaa agtcaagcaa atggtgcgtg ataatcaggg
     6841 tagtggaatc aatcgatgat gttttttatc ctatcgaaaa gcaactagga atgatagaag
     6901 aagatcctaa tacatcgcca gttgtaatgg atcaatttga aacatactta attgatgaag
     6961 gattcaaagt gaagaaaaaa gattttactt attttacaca ggaatcaatt actgaagaat
     7021 tgatgaagct atactatgac gcgtacgcaa aagatcctgt tgtgaccagg tacattcgca
     7081 aactattcag tgaaaaacga gaaatcctta gtacgactaa gctgacctat agactgctcc
     7141 tttggtccgc agataaaaaa agaacctttc acgactcgtg aagggttctt tttatgattt
     7201 tattatattt tgtagtaacg aatatcattt tcgatctttg taatcgaaaa aggtacatct
     7261 gaagtatatt ctgcacattc tccgtgttca ggaagcgtct cactgaaaat cgtttcatat
     7321 tcgtcaacag tgatccgtgt tcgagaatct agcatctctt gatgagattg tgcgaagaga
     7381 tattcttgat agttttcttc cagataacct gtaaaaaatt cacttactgc accagaaccg
     7441 tagctgaata gaccgatgcg atctcctggc tgtagtgatt tcgaattttc cagtagagaa
     7501 gttagcccca ggtataatga accagtgtaa agattaccga ttcgtcggct gtaacggatg
     7561 ctttcttcat agcgagccat aagacgttcc tgattttctt cgtctgtttg gtctaatacg
     7621 ctttgcaatg ccttttttcc catcttagta tacggaatat ggaaagcaat cgcctgataa
     7681 tcttcgagtc ctcgacccga caattcttta tgtcgattcc aaactttttg gaatgattcg
     7741 atatacgtag aattagataa aggaccatca acaacaggaa attcgctata atctggacgc
     7801 cagaaatcat agatatcttc tgtcagaaat acgctgtcgt cttcaatcga taaaatacgc
     7861 gggttttgag tgatcatcat cgcaacagca ccgacacctt gcgtcacttc accaccgctt
     7921 gccaagccgt aacgagcaat atcacttgct atgactagta cttttcgttc tggatgattt
     7981 ttgacatatt ctttcgccat gtgcaaagct gcggtgccac cgtagcaagc ctcttttact
     8041 tcaaaagaac gagcaaaaga ttggattttc agtaaatggt ggataattac cgcactcgct
     8101 tttgaatgat caatcccgga ttctgttccg acgatgacca tgtcgattag ctcacggtct
     8161 ttttctgtta cgattttgct ggcagcattt gctcctagtg taatgatgtc ttcatttgca
     8221 cgattgactg ccatttggtc ttgaccaatc cctatatggt attttgcagg atcatcccca
     8281 cggctttctg ccaactctgt catatctaaa tataaattag gaataaaaaa ggaaagacga
     8341 tcaatcccta ttttcatttc aacacctctt tacttatgat aaaaaactta ctttactaag
     8401 gtatcataaa aagattaaaa gaaatataaa aaagagaata tttaaggatt gttaaaattt
     8461 aatcttagaa aaaaacaact ggaacaagag ctatttgttt ttacagcaaa gaatggtata
     8521 tttttgtagg aggtggctta cttgaaagaa gtcgttatga tagatgctgc aagaacgccg
     8581 ataggaaagt atcgcggaag tttaagtcca tttactgcag ttgaattagg cacacttgtg
     8641 actaaaggat tattagataa aacaaaactg aaaaaagata aaatcgatca agtaatattc
     8701 ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca gacagattgc tttgaacagc
     8761 ggtctccctg tagatgtccc agcaatgacg atcaatgaag tttgcggatc tggtatgaaa
     8821 gcagtgatct tagcacgcca gctgatccaa ttaggtgaag cagaacttgt gatagccggc
     8881 ggaacagaga gtatgtctca agcacctatg ctgaaaccgt atcagtcaga aacaaatgaa
     8941 tatggtgaac caatttccag tatggtcaac gacggattga ctgacgcatt ttcaaatgca
     9001 catatgggat taaccgcaga gaaggttgca acacaatttt ctgtgagcag agaagaacag
     9061 gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg ctgtcgaagc cggtgtattt
     9121 tctgaggaga tcatcccagt caagatttct gatgaagacg tgttatctga ggatgaagca
     9181 gttcgtggaa atagtacatt ggaaaaactg ggcacgttac gtacagtatt ctcagaagaa
     9241 ggaactgtaa cagcaggaaa tgcttcgcca ttgaatgacg gtgcctctgt ggtgatcctt
     9301 gcatccaaag aatacgcaga aaataataat ctgccttatt tagcaaccat caaagaagta
     9361 gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc caatcaaagc cattcaaaaa
     9421 ttgacagata gatcaggaat gaatttatca acaatcgatc tttttgagat caatgaagca
     9481 tttgcagctt cttctatcgt agttagccaa gaactgcagt tagatgaaga aaaggtcaat
     9541 atatatggag gagcaatcgc attaggccat ccaattggtg caagcggtgc acgtatcttg
     9601 actacattag cttacggatt gcttcgtgaa cagaagagat acggtattgc ttcattatgt
     9661 attggtggag gtttaggctt ggcagtcttg ttagaagcga atatggagca aacacataag
     9721 gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg aacggcgcag tcaattaata
     9781 gaaaaaaatg tattgacaca agaaactgcg ttgatttttc aggaacaaac actttctgaa
     9841 gagctctccg atcacatgat cgaaaaccaa gtgagtgaag tggaaatccc aatgggcatc
     9901 gcgcagaatt ttcaaatcaa tggtaagaaa aaatggattc cgatggcaac agaggaacca
     9961 tctgtcattg cagctgcaag taatggtgca aaaatctgtg gaaatatctg cgcagaaaca
    10021 cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa aatcggagta tcaagcagtg
    10081 atcaatgcag ttaatcatcg aaaagaagag ctgattcttt gtgcaaatga aagttatcct
    10141 tcaatcgtga aacgcggggg cggtgttcaa gatatctcta ctcgggaatt catggggagt
    10201 ttccatgcat acttatctat tgatttttta gtggatgtaa aagatgcaat gggcgctaac
    10261 atgatcaact cgattcttga gagtgtggca aacaagttac gggagtggtt ccctgaagaa
    10321 gagattctat tcagtatttt aagtaatttt gctacagaat cattggcttc tgcctgttgt
    10381 gaaatcccat tcgaacgctt agggagaaac aaagaaatcg gtgaacaaat tgccaaaaaa
    10441 atccaacagg caggggaata tgcgaagctt gacccttacc gtgcagcaac gcacaacaaa
    10501 gggatcatga atggtataga agctgtagtg gcagctacag gaaatgatac acgtgcggtt
    10561 agcgcttcga ttcacgccta cgcggcaaga aatggattat accaaggatt aacagactgg
    10621 cagatcaaag gggataaact agttggaaaa ctaacggtgc ctttggctgt tgccacagta
    10681 ggcggagctt ccaatatcct gccaaaagca aaagcatctt tagctatgtt agatattgat
    10741 tcagccaagg aactagcaca agtaattgct gcagtagggt tagctcaaaa cctggctgct
    10801 ttgcgtgcat tagttacaga aggaatccaa aaaggccaca tgggacttca agctcgttca
    10861 ttagcgatct caattggggc tattggtgag gaaatcgagc aagttgcgaa aaaattacgt
    10921 gaagcagaaa agatgaacca gcagacagct atacaaatat tggaaaaaat ccgggaaaaa
    10981 taaaaaagca atatctttag aagaataaag caagatttac agttatttta tttactgcaa
    11041 atcttgcttt tttctctatc agaaaatatg tttattatta gaatttttta tagttaaggt
    11101 taggcatctt aagaaatcag gcaactccaa gatatcttca ggtagaagag aagtcgccta
    11161 acattgtagg atcataggtg atttgttgga caggtcaagc tgatatttga gcctgatgtt
    11221 agaaggaatt tctttttact tgctgtagaa attattatat gactaaaaag gctgggattt
    11281 taaatcccag ccttttatga caaatagaat ttttatcgat cagtaatcgc tgtcgctgca
    11341 aattgttcga tcaaaggaat caaagtcaat ttgactttgt atttccgttc gagtgctttt
    11401 tcgataacga actcattttc agtagtcata gaaatagttg ctaatttacg aggttcatca
    11461 gcattttttt cattaataac tacttcatgt tcattttgtt ctgtgtaaaa tttaggatac
    11521 tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg cattcgtatc agttgagcgt
    11581 gtattttcag ttgtgtccgc ttttggtttt tccgtttttt cttctggcac actgactgtt
    11641 tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt catcgttttt caatcgttga
    11701 tcattccagt aagacacgat ttcaataaga agattgtcac ggaatcgttc gaaaatcccg
    11761 ttttctcctg aacgaattct ctttaataca gtattgaagt tgtcatcgat tggcacgttg
    11821 atccgtgtat cttcatttgt tttcccagct aatccgatcg ttaagatttg acggtttttg
    11881 ggatcaagca tgacttgtaa cggcaaacca tagcgtcgca agctctcttc ttctagagaa
    11941 cggaataatt gtcctcttac accatccaat gaaggacgga attgatttaa taatttttgt
    12001 ttctgttttt tcttcatatg ttctctcctt cgctcatacc ctttcgatta taagaaaaaa
    12061 acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta tacgcaaatt acaacagaaa
    12121 aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa atggaacgga ttatgtatat
    12181 atacataatc cgttccattc tttctatttt ttcggtatca aggcaaaaac aggtagttca
    12241 ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt
    12301 tttttcagtt cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt
    12361 ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag
    12421 agagaattca agcgttcgat tggatccata aaatcacctt tcgacttaaa attgggtagt
    12481 atctgggtct tttgctttgc cgactacacc atctaactga tcgatttgtt tcatttcttc
    12541 ttctgttaat tcaaaatcaa ataattcagt attttctttg attctgcttg gtgtcactga
    12601 cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt
    12661 cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca tcgaagattt taccagtgcc
    12721 taatggacta tatgcttcga ggatcatatc atgttttttt gcatactcaa ctacagttgg
    12781 ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc ggcataattt ttgctgtttt
    12841 tgctagtgta tctagatggt ggggtaagaa attgctcaca ccgattgctt tgattttacc
    12901 tgcttcatac agttcttcaa atgctcgcca tgtatctgca tttgcttgtt cccaattatc
    12961 acgaaaagca acagggtttg gccagtggat caaaaacaga tctaaataat ctgtttggag
    13021 cttcttcaat gattcttcaa aagaagacat cacaagttca tagctgtggt ttgcattcca
    13081 taattttgtt gtcaagaata tctcttctct aggaattcca ctttccttaa tcgcttggcc
    13141 gacactttct tcattcttgt atccttgggc agtatcgata tggcgataac ctgcagccag
    13201 cgcttcttta acagaggaaa cagcgacatc cccatcaggt gtttgccatg tgccgaatcc
    13261 tactaccggg atttcgtaac catttaatag acgataagtg cttgttaatg aattcatact
    13321 ttcagctcct tttttattcg ttcaactata agtgtagcgc atttttcgaa aaaaagaatc
    13381 cattttgttt ctactcttga aatttttgtt taaaagaaaa tgattttgat tctggtattt
    13441 ttgatttttt ttccgtaaac taagacagaa gggaatgaga aaatggatat ctatttaaaa
    13501 aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc acaaaaagag
    13561 ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca aaaaatctct
    13621 tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga atcacttaaa
    13681 atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc
    13741 taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta tgaattagat
    13801 acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac tcactttgtt
    13861 gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat tctaggggcg
    13921 aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac ctacgaatta
    13981 attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg aagagtgatc
    14041 gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa agtagccaag
    14101 catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt gaaagaagct
    14161 gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc
    14221 ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga gcaaggattt
    14281 gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa atttggaaaa
    14341 caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac
    14401 ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat gatcaaaaat
    14461 gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt caagtaccag
    14521 tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa
    14581 gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg
    14641 gaagcagaag caactccttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
    14701 tatctaataa aattttaaga ccatttacta attatcgatt ttttctgccg catttttagg
    14761 cacttcagaa gcctttattt cttcccagct taatacacct ttacgaggat tgactttgag
    14821 tttaagatac gcattcatct ttaatggatg ttctctttct tcgcgaagcg tcacctgttt
    14881 tttttcacca tctttattat aagccgcttg cttgtaggta taagtcgtga atttctctcc
    14941 gttatctgct tgggtagctg acatttcgcc attcgtcgtg atttttgtat aataagcttc
    15001 gccgccgtaa aaataatgat aagctgcaaa acttccgccg agaaatatgc ctaaaacgac
    15061 aagtacgcca attaattttt tcatgtactt cacctctttc cttattatta acgaaataga
    15121 agatttcgtc tattgaaagt tgttggcaac agctgaattt taaacttttc ctcattttgt
    15181 tcttattgct tcaaaagaaa gttaaggact atcttgaagt ttttctcaaa aaacacattt
    15241 ttttatttat aaaaggtact tttttcgcgt ataagacaag cgagtgctct tagttgactt
    15301 tgaccaatat tgacgtataa taagcttagt tcgaatctta caaaaagtaa gtcggacgta
    15361 ttctttttga tttagtcaaa aaaagactat aataaaaagg tgagagctga aatttttcag
    15421 tgatctatat tatttaggag gtttgtaaat tatggcaaaa gaacattatg acagaagtaa
    15481 accacacgtt aacattggta cgattggaca cgttgaccat gggaaaacta ctttaactgc
    15541 tgcgatcact acagtattag gcaaaaaagg cctagcaaat cctcaagact atgctagtat
    15601 tgatgcagct ccagaagaac gtgaacgtgg gattacgatc aataccgcac acgtagaata
    15661 tgaaacagaa aaacgccact acgcgcatat tgatgcacca ggacacgcgg actatgtgaa
    15721 aaacatgatt acaggggcag cacaaatgga tggtgcaatc ttagttgttt ctgcaactga
    15781 cggtccgatg cctcaaacac gtgaacacat tttattgtca cgccaagttg gtgtaaaata
    15841 cctgattgtt ttcttgaaca aagttgattt agtcgatgat gaagaattga tcgatttggt
    15901 agaaatggaa gttcgcgagt tattgagcga atatggtttc ccaggcgatg acactcctgt
    15961 gatcaaaggt tccgcattaa aagcattgca aggcgatcca gatgctgaag ctgctattat
    16021 ggaattgatg gatacagtag atgaatatat cccaacacca gaacgtgata cagataaacc
    16081 attactattg ccagtggaag acgtcttctc aattacaggt cgaggaactg ttgcctcagg
    16141 tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta gagatcgtag ggatcaaacc
    16201 tgaaacacaa aaagcagttg taacaggtgt agaaatgttc cgtaaaacgt tagattacgg
    16261 ggaagctggg gataacgtag gcgtgttgtt acgggggatc caacgtgacg atatcgaacg
    16321 tggacaagtg cttgctaaac caggttccat tactccacat acaaaattca aagcagaagt
    16381 gtacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcaaca actatcgtcc
    16441 acaattctac ttccgcacaa ctgatgttac aggaacaatc acattgccag aagatacaga
    16501 aatggtcatg cctggtgaca acgtgacgat tgatgttgac ttgatccatc caatcgctgt
    16561 tgaaaacgga acgacattct caattcgtga aggcggacgg acagtgggtt caggtatcgt
    16621 tacagagatc gaagcataag aaacgcgact cgaatatttt ggtaatgaaa aatgtttaaa
    16681 ataaaagagc ggtccaaaca ggatttctgt ttggaccgct ctttgttctt caattgtata
    16741 agaagagatt gtagaagcat gaactttcgt tttacttcag tctcttttat tcatcatgag
    16801 agtgttcatc tatcggtatg cagtttttaa tactttcttc gtatccattt tttcaaacca
    16861 cttattctac cttgtgtctg ctcaactggc gcattatcaa taatcagcaa agcaatcata
    16921 acatatgcaa tccaactatc tctagaatat agagtataac gtgagaccca gtttgtagcg
    16981 tacttgcttt tatattctct taatccatgg aaagaataaa aatgagaacc aaactcgtaa
    17041 accaagtatg caatcctttc ctgtaaaaaa ctctttctgg aagttccgac atttgaaaga
    17101 ggggccatcc ctaaattgaa ccattggata tgttcttctt tcatataggc aaacaaatgc
    17161 aagaacaaga aatccatact gccagaaggt gcttttttag gatcatatcg catcagatca
    17221 atcgttccta ctttattgtt cgtgtaagta ggcatgatcg ttgcaaaagc gacaatttct
    17281 tcttgggtat ttttgacaac tgcaataggc gctctttgta gataatcttc agagaaaaag
    17341 cctaaagaaa accctttttc ctttcgtgaa cccaaccaat tatcagagat atttttgaaa
    17401 gtactcattt gctcagtaga aaatggtggt tgtaagacat caaatgtaaa tccttctcgt
    17461 tcgatccgat tcaagacagc acgagtgccc ttcatttttt tccctgaagt tgtaaaacta
    17521 ttcaggtcta cataagcttc ttcccccatc ttaatgaaat cgtagccgaa ttcatgcaaa
    17581 atcataacaa tctcttcgct tgtttcgtag aaaactggta aatagcatag tcgatctgtt
    17641 tcttcgataa aagcttcgat tgcttctgga aaatcttctt tcttaccaga aggatcaccc
    17701 attacaatac atttattatt gaagcaagcg aattggagaa gaacagttgg ttcaccgtct
    17761 ttttcatagg caaacatccg cttatctttt aagaagatca attgactatc ggagtttcct
    17821 ccataagttg taaggatctt cagggccttt tcttcattaa aggcttcgcc aatctgtttc
    17881 ttttctcctt gaaggaaatg aacaaataga acgatcatga aactaacagc gatgatggcc
    17941 aacaatcccg aaaaccaaat cttttcagaa ggaaataaga aaaaggaaat aaaatggtga
    18001 cgccgatgag ggaaatccgg cagattgtat accccaataa cgatgtaaag caaggacagt
    18061 gcaccaataa tgattccatc gatcgtacgc cactcccatg aatagatcaa ttgttcccga
    18121 aataattcgt ttttagaagc aagaatgatc agaagcagaa tagacaagaa aaccaccggt
    18181 gtgaaactaa aatcacttaa taaaacataa agtaaagcta gaacaatcaa gaagattgta
    18241 ggcaaatatg ctcgtttcac acgtgctgcg atccctctgc ccataatgat taaaagaaat
    18301 cccaatagta tactaggaaa ttggataata aaatgaaatt tcaatgggtt caaactatga
    18361 agccagcgaa actctgtaaa agcttgcggg atagtggcag aaagtactag catgattcca
    18421 gaaaagtata ataagacaac cacgatttta tgcgcaattt ctgttgctaa ttgtttaggg
    18481 ataccagaat aacgctgatc aaaagtggaa ccgatatttt tgaagaaaaa gacgattcca
    18541 atcaaaaacg gaatgatgta gtagaacagg cgatagagca agatccacac aacgactatt
    18601 tctcttggca caccaatagc ggacaacccg ataatcatca ttacatcgaa actcccaatt
    18661 tctcctggaa tcatagacac gattcctatc actgaagcag caatgaataa cggaattgtt
    18721 tgccacagat caatccggat ttccattaaa taaccaacag aaaggaaact aaacaggaca
    18781 ccggtccatt ccaacaatga aactagcaat agctgtcctt gagttttaag tgaggtacca
    18841 ccaaggaatc ctttcttttt gaaagtagta aataaaaaga cgacaggaaa atatagaccg
    18901 ccgccgatca accatatcca atattgcttc aaaaaaggag caactggcgt gaagactaca
    18961 agtaaaaaag aaagcagact gtaaatagaa agtccagcca tcaaaaacaa gaaaactttc
    19021 gataatgctt ggatcacgtt tctgctctct ttcttttgtc catatagttc agagcgaagc
    19081 cccacactaa caaacccgcc gaaaccggca atattgttga ttgtattgat cagccagctt
    19141 gtctcaaaca agtaacgagg attctgcttt tgttcaagca tccgattcaa aataatatca
    19201 taaccaatca taggtaacac agagacaaga ccaatcaaca gcataagtcc gcttttccat
    19261 acaggtatag tggcaaacgt ttctcctaat tgctggatag atagagtttt accgatggac
    19321 atcaattcac cgacaataat gacaatgaca gaaatcaaaa agattgtttt gaacagtcct
    19381 aggtggtttt tcagccattg tatggtattt tttaacaaat aaatcacctt ctattcctaa
    19441 tagttatgtt tcagaaagaa attgaagaac ttctcgattg aagcgttcag gatcttttct
    19501 agctaattca tgtccttgtt ctttcacaag cacaaaggaa gcttttggta tagttttagc
    19561 tatatacaaa gaatgtttta gcttgattac atcttttttt cccacgatga tcaaagtggg
    19621 ggagttgatt ttttttaaat cattttctgt aagcccgatg tcatgcagca aaagtttgat
    19681 aactaaaaga tttttgcgaa gacttgggcg aaataaagag agtaaccata cccatgcata
    19741 atgaatatta ctgatgactc tggcagaaaa acgaacgcct ttaacaagcg tgtttccaga
    19801 atttaaaatc aatcgatgaa cttttttagg gaagctgctg gcaaatacca gtgctagatt
    19861 tgctccatca ctaaatccaa gaaaatctgc ctgatcgatt ttttccagca acatgatcgt
    19921 attcagatcc tcggccatta actgaaaatt caacatagat gcttcgtttg tcgaacgacc
    19981 atgtcctcgg ctatctacta gatacacggt atagtagcgt tcgagtacag ggacctgttc
    20041 tgaaaaaaag cggccgctgc cgtcattgcc atgcagtaaa aagagaggga agccttgacc
    20101 gctcttttca tagtaaattt cgctcccatc tggcattttt gcatatttct tttctttttt
    20161 cacataatca cctactgtgt aaagtataac gattatatca gtcattgggc aattgttttt
    20221 actgaaaaac aacgatcatt ttcgtaagat gacaaaaaat acaggaaaat tcattttttc
    20281 ttaaggcgta cacagaaatc aaggaagaaa tagccaagaa gataaagaaa tagtaagata
    20341 aaaaaagatg tcaaaataac taggtgatga aatgaagcga aaacgattat ctattatccg
    20401 tattcttttt tacatgatca ttctgacggt tattggtgcg gtgttgtttt taggaggaag
    20461 aacttatcgt tcggtaaaac gagtggaaag ctatcaaata gaaataacaa cagctgcaaa
    20521 aaattatcat atggaaaact acgagaattt gatcaaggcg ataatattga ccgaatcaaa
    20581 aggaaaaggg acagatctca tgcggagctc ggaaagtctg catggagaag ctgagatcat
    20641 tgataatcca gctgacagta ttgatcaagg tgtcaaatat ttggcggaaa tgatagtaga
    20701 agcaaagaaa caaggatgcg atttatggac agctgtccaa gcatataatt ttgggaaaga
    20761 ttatattgcc tatgtaaaaa atcatggcgg agaaaacaca gtagaattag cagaagcgta
    20821 ttctaaagat gtgctgagcc cacttttagg aaatgaggaa gggaaacaat accgatattg
    20881 gcggatccag tccttgcttt acaatggcgg ctatctctat cataatggag gtaacatgtt
    20941 ttatcctgat attgtcaaaa tgaatgaaaa aataatagag acctatgaaa aagtctttaa
    21001 gtaaaatagc aggaaatgtt caatcatgaa taaaattaaa tgaaagaagg agtgcgcaaa
    21061 tagtggaaaa aaggcaaaaa atggaaaatc aagaagtggg gtacacaacc aaagactgga
    21121 tgttacggtt tgtgaaggga atgtttatcg gttcaggatt tatcttgcca ggagtcagcg
    21181 gtggtgcatt agcagctgtc tttggcatgt atgagcggct gatttctttt ttagcccacc
    21241 ttacaaaaaa tttcaaagaa aatgttttgt tttttctgcc tgttggtcta ggcggagtga
    21301 caggcatctt tctactttct tttttagtca gttttttatt aggtgcgtat gaaacaacga
    21361 tattatggtt ttttgtcgga tgtatcgctg gaactgttcc tgcgttatgg aaagaagcag
    21421 ggaaaaaagg aagagatact tctgatgtga tcatcatggt tgttactttt gttctggctt
    21481 atttgttttt attatacggc gctcaattat ttgacgggca agtcgatcag aattttggaa
    21541 catggctgat tgccggcgga ttgattggtt tgggtatgat cgtcccagga ttgagccctt
    21601 ctaatttttt ggtgtatatg ggattgtata aagcgatggc tgacggattt aaagaagtac
    21661 gacttgaagt gattgtgccg atcggaattg gtgggattct ttgtgttctt ggattgtcaa
    21721 aaatcatgga ttacattttc tcaaaggcat atagcaagct attccatttc attttaggtg
    21781 tagtttttgc ttcaacgatt atgatcattc ctaccgatta cgcgggattg ggagttgctg
    21841 gggtactagc ttgtcctgtt ctttttatag ccggtacagc actaggttgg tggatgagcc
    21901 gtttggagga acaatataag taaagataga ttgataataa aaacagcaca cgggtgattc
    21961 aaacaaaaag gttggcatct tttttgtaaa atcattcgtg tgtttttcta taaattttat
    22021 aaaaacaagt tgtttttaat cttggaacac gctagactta aacacgtgat tatttttgaa
    22081 agttggcgga aaatggagaa aaagaaaatg aatggactta cacagcaaga ggtagttcag
    22141 aaaatggctt ctggccagca aaatgactac caggaagatg catcaaaaag tacaaaacaa
    22201 atattcagcg ataatatatt gacgttattc aattttctga actttggtat tgggatttgt
    22261 ctgttatttg taggtgcgta ttccaacatg gcgtatttag caattattgt cgtcaatatc
    22321 gttattggaa tttatcaaga aatacatgca agaaatcttg tacggaaatt atcgattgtt
    22381 tcccaatcag aagtactagt gatccgggac ggtaaagaac aatcgatttc tactaaagag
    22441 ctggtattag gagatttggt aaaaatcgga gcaggagaac agataccagc cgatttacag
    22501 gttatatctg gacgggcaga agcaaatgaa gctcttttga caggcgaatc tgatttgatt
    22561 gtcaaagaaa ctggagctga attgctttct ggaagctttt tgacaagcgg ttctgtcatg
    22621 gctgaagtta tccgagtagg tgcagataat tatgctgtcc gcttgactag cgaggcaaag
    22681 actcacaaag ctattcgttc tgaacttgta gattcgattc gcaaagtatc caaattcact
    22741 agtttcgtga ttattccttt ggggatcata ctatttttgg aagcactgtt catccgcgat
    22801 gcttctatca aaatttctgt tattgcatct gcagcagctt tgttaggcat gcttccaaag
    22861 ggtttggtat tgctaataag tattgcatta acgacagggg taaccaaact ggcaaaaaaa
    22921 cgaatccttg ttcaagacat gtattcaatt gaaacgctgg cccatgtcga tacattatgc
    22981 ttggataaaa cagggaccat tactgaaggg aaaatgagta tccagcgggt agaagcacta
    23041 catccgctgt acgagaaagc catcccagaa attatgggga cgtatctggc agaaagcagt
    23101 gataacaaca tcactatgcg ggctatgaga gattattttg agctttctaa tcggtatgat
    23161 gtgacaaaca aagtcgcatt ttcttctgat cgcaaatggg gcgcgatgga atttccagaa
    23221 ctgggagtcg tgtacgtagg agcgcctgaa cgtttggtgg aagaagatcg gcttccggac
    23281 agtctaaaaa cagcccaagc gaatggctat cgcgtactta tgttggggat cgctccaaat
    23341 cagcaattga acgaagaaaa accagcattt gttgagccgg ttgctctgtt tgaaatcgat
    23401 gatccaatcc gaaaaaacgc tcaagaaaca ctagcttatc ttcatgagga aggtgtggat
    23461 ctgaaagtga tttctggaga caatcctttt actgtctcca atatcgctag acgtgcagga
    23521 ttaccgaatt atgatgcgta tgtcgatctt tctcaaatta ctgaagaaat ggaagtgcga
    23581 gaagctgctc atcgctatac ggtttttgga cgagtgagtc cgcagcaaaa gaaattgctg
    23641 gtaaatgaat tgaaagaaag cggcagaacg gttgcaatga caggcgacgg tgtgaatgat
    23701 gttttggcgt taagagaagc agattgcagc attgctatgg cagaaggtga tggagcaaca
    23761 cgtcagattg cgaatctggt attgttggac tctgatttta ctacattgcc agaagtcctg
    23821 tttgaaggac gccgagtggt caacaatgtg acgaaagtct caggcatctt ttttatcaaa
    23881 acgatttatt catttatttt atcgattata tgtgccgtta cagcaattgg atttccgttt
    23941 atccctatcc aaatcacgct gattgattta gcgattgaag ggtatccttc cttcttttta
    24001 tcttttgaac aagataaaag aaaaatcact taccgttatt tgcctacagc acttattaat
    24061 gctttaccaa atgccttgct tgtagtagtg aatatcattg cggtgtatct acttggaaaa
    24121 acattcgcat ggggaaatgc tgaaactact actttgatgt attacttgct gattgggatc
    24181 agttgcatgg cagttgtaaa agcttgttat cccttcaacc cattgcgcat cttcctagca
    24241 gtaacgacga tcgtagggat atatgtagct gcaatgctgt tccatggaat tttggaagta
    24301 aacttagggt tgggagagag cgtaggatac ttctttgtat tcatgctcgt aaatattgtt
    24361 cttcgagtat tgtactggaa ggctgatatt caaaatcagt tactgaaaag agtagcaaat
    24421 tgatgcttaa tgagatagaa atgtgttata cttgaaaaag caatgaaata tgatacaatc
    24481 aaacatgtat aattgtgtcc tttaaaatcg cactgatttc agttagtgcg attttttacc
    24541 ggttattctc ctgaaatatc ttctgttaaa cccaaaagat atcaatagag cagggggtga
    24601 aaaaatggct caacggattc ctcaagaggt tatcgaaaca gtacgcagtc aaacgaatat
    24661 cgttgaggtg attggacaat atgtccagtt gaaaaagtct ggtaaaaatt acttggggct
    24721 gtgtcctttt catgaagaac gtacaccgtc tttttctgtt gcagaagaca agcagatttt
    24781 tcattgcttt ggttgtggta aaggcggaaa cgtgtttact tttcttcaag aactagaagg
    24841 tctaagtttt ccagaagcag tggtaaaagt ggcagacttc gaacagatac cgttagaaga
    24901 tcaatggcgt cagcgtacta tagctgtcca aaatcctgaa tctgctacgg ggaaactgat
    24961 tgctgctcat gaaaaagcag cggaaatcta tcatcacatg ctattgcata caaaagctgg
    25021 acagccagct ttagaatatt tgcaaagtcg tgggttgtct ttagaattaa ttgaagaatt
    25081 caacataggt tttgcaccta atgagcgttc ttttcttcag caagtattca agaatgaatc
    25141 aatttcaaat gaattgttag aacgctctgg attgtttgtc acgcatgatg atggccgtat
    25201 gtctgatcgt ttttatcaaa gagtgatgtt tccacttcgt aattctcaag gccagacgat
    25261 cggtttttca ggacgctggc ttgcacctga aaaagggcag gaaaaagatc agcccaaata
    25321 cttgaatagt ccagaaacag aactgttcaa taaaagacaa gttttattta atcttgataa
    25381 agcaagaagc gatatccgga aaaacggaga aattttgttg ttcgaagggt ttatggatgt
    25441 gattgctgca tggcaggctg gtatcaaaac tggattagct tctatgggga caagtctaac
    25501 agctcaacag atccaacaaa tggaaaagct gacgaaagaa ttggtctttt gctatgacgg
    25561 agacaacgca ggttttgaag caaccaatcg agggattgaa ttgcttcggc aaaacagtcg
    25621 attagcactt tctgtcgtag tcgttccaga aaagcttgat cctgatgaat atctccgtaa
    25681 gtatggagaa gcatctttcc aagaattagt ggctcatggg cgcgaaacag tctttacttt
    25741 taaatcacgt tatttaaaac aagggaaaaa tttagataat gaaaaagaca agatcgaata
    25801 cctcgaagaa ttactagttg aacttagccg agttgtttca ccaatcgaac aagatatgta
    25861 tctatctcaa ctgtcaacag agtttcagat cggcagagag acgatacaaa aacaactgcg
    25921 cgatcttcga aggacaaatc agcaaaatcg tcaagaacct caggaaagtc aacacactca
    25981 ggttacgaga caagaaactg cacggaaaaa gagacctttg acgcaagtag aaaaggcaga
    26041 gcagattcta ttatatcgtg catttaaaga agtttctgtc cgtaatattt taaaagaacg
    26101 agaatttcag tttattcatg atgcatatgc agaagtttat tttttattcg atgcatatgt
    26161 ctcacaacat tatgaattca accttgcaga gtttttagac tttttgcaag atgaaaattt
    26221 aaggcggttg gtggtggaaa tcgaatattt accggtggca gaagaaagtt cgccacgaga
    26281 aatccaagac ttgctagatg tgatcagcaa atctggctta gctgatgaaa taacattaaa
    26341 aaaacaaatg cagcaagaag ccagacgaac tggaaacaaa cagcttgagc ttgaattgac
    26401 gattgaaatc atcaatttaa cgaaacagtt aaaacaagcc aaatagctac tcaagggggg
    26461 ccttctttta tggcaaatgg aacagataaa aaaacgtatg aagcagcagt agcagctttc
    26521 atcaaagaaa acaaacccaa acgacaagtt gtatatgatg atttatccaa tcagcttgct
    26581 acaccattca ctttgaatgc agatgaaatg gacaaattga tccaaaagat tgaagacgca
    26641 ggtatcagtg tggtggatga aaatggtgat ccatcaattc acagcttgaa gagtgctgag
    26701 aaaaaagctg aacaagcaaa aacagaagat ctttctgcgc caaccggtgt aaaaatcaat
    26761 gacccggttc gtatgtatct gaaagaaatt ggccgtgtct cccttttaac tgcggaagaa
    26821 gaagtagcgt tagcattgaa aatcgaagaa ggcgaccaag aagcgaaaca gcgtctggca
    26881 gaagcaaacc ttcgtttagt agtaagtatc gctaaacgtt atgtaggacg aggcatgcag
    26941 ttccttgact tgatccaaga aggaaacatg ggactgatga aggcagttga aaaatttgac
    27001 taccgcaaag gatttaagtt ttcaacctat gctacatggt ggattcgtca agccatcact
    27061 cgagcaatcg ctgaccaagc acgtacgatc cgtattccag ttcatatggt tgaaacaatt
    27121 aataaattga tacgtatcca acgtcaattg ctgcaagacc ttggaagaga acctacgcca
    27181 gaagaaatcg gtgcggaaat ggatcttcca acagaaaaag tccgagaaat cttgaaaatc
    27241 gcgcaagaac ctgtttccct tgaaacgcca atcggtgaag aagatgactc tcacttaggt
    27301 gatttcatag aagaccagga agcaacaagt ccagcagaac acgcagctta tgagttacta
    27361 aaagaacaat tggaagatgt actagataca ttgactgatc gggaagagaa tgtccttcgc
    27421 ttacgttttg gtttagatga tggccggacg agaacattgg aagaagtagg gaaagtgttt
    27481 ggtgttactc gggaacgtat tcgtcagatc gaggctaaag cattaagaaa attgcgccat
    27541 ccttctcgtt caaaacaatt aaaagatttc ttagaataag cgtggactat tgaccagaag
    27601 agaaatcagt aaaactgttt ggtttatttt aaaag
//
LOCUS       DBGZHO010000032        27528 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.032, whole genome shotgun sequence.
ACCESSION   DBGZHO010000032 DBGZHO010000000
VERSION     DBGZHO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.032"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            207..746
                     /locus_tag="ACN3HL_001581"
     CDS             207..746
                     /locus_tag="ACN3HL_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006459.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
     gene            1766..2935
                     /locus_tag="ACN3HL_001582"
     CDS             1766..2935
                     /locus_tag="ACN3HL_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HHC8006460.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3408..3962
                     /locus_tag="ACN3HL_001583"
     CDS             3408..3962
                     /locus_tag="ACN3HL_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006461.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(4135..4572)
                     /locus_tag="ACN3HL_001584"
     CDS             complement(4135..4572)
                     /locus_tag="ACN3HL_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006462.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            4620..5567
                     /locus_tag="ACN3HL_001585"
                     /pseudo
     CDS             4620..5567
                     /locus_tag="ACN3HL_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            5838..6273
                     /locus_tag="ACN3HL_001586"
                     /pseudo
     CDS             5838..6273
                     /locus_tag="ACN3HL_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            6289..7122
                     /locus_tag="ACN3HL_001587"
     CDS             6289..7122
                     /locus_tag="ACN3HL_001587"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006463.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            7367..8392
                     /locus_tag="ACN3HL_001588"
     CDS             7367..8392
                     /locus_tag="ACN3HL_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006464.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            8530..8655
                     /locus_tag="ACN3HL_001589"
     CDS             8530..8655
                     /locus_tag="ACN3HL_001589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006465.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            8680..9795
                     /locus_tag="ACN3HL_001590"
                     /pseudo
     CDS             8680..9795
                     /locus_tag="ACN3HL_001590"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            9878..10774
                     /locus_tag="ACN3HL_001591"
                     /pseudo
     CDS             9878..10774
                     /locus_tag="ACN3HL_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            10790..11614
                     /locus_tag="ACN3HL_001592"
     CDS             10790..11614
                     /locus_tag="ACN3HL_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006466.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            11646..12956
                     /locus_tag="ACN3HL_001593"
     CDS             11646..12956
                     /locus_tag="ACN3HL_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HHC8006467.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            13104..14363
                     /locus_tag="ACN3HL_001594"
     CDS             13104..14363
                     /locus_tag="ACN3HL_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHC8006468.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            14373..15245
                     /locus_tag="ACN3HL_001595"
     CDS             14373..15245
                     /locus_tag="ACN3HL_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006469.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            15257..16087
                     /locus_tag="ACN3HL_001596"
     CDS             15257..16087
                     /locus_tag="ACN3HL_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006470.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            16127..18310
                     /locus_tag="ACN3HL_001597"
     CDS             16127..18310
                     /locus_tag="ACN3HL_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HHC8006471.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            18371..19591
                     /locus_tag="ACN3HL_001598"
     CDS             18371..19591
                     /locus_tag="ACN3HL_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HHC8006472.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            19588..21048
                     /gene="gtfA"
                     /locus_tag="ACN3HL_001599"
     CDS             19588..21048
                     /gene="gtfA"
                     /locus_tag="ACN3HL_001599"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HHC8006473.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            21125..22231
                     /locus_tag="ACN3HL_001600"
                     /pseudo
     CDS             21125..22231
                     /locus_tag="ACN3HL_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            22553..22762
                     /locus_tag="ACN3HL_001601"
     CDS             22553..22762
                     /locus_tag="ACN3HL_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HHC8006474.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            22755..22904
                     /locus_tag="ACN3HL_001602"
     CDS             22755..22904
                     /locus_tag="ACN3HL_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HHC8006475.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            23058..23723
                     /locus_tag="ACN3HL_001603"
     CDS             23058..23723
                     /locus_tag="ACN3HL_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8006476.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(24007..25092)
                     /gene="xerS"
                     /locus_tag="ACN3HL_001604"
     CDS             complement(24007..25092)
                     /gene="xerS"
                     /locus_tag="ACN3HL_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HHC8006477.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            25426..25659
                     /locus_tag="ACN3HL_001605"
     CDS             25426..25659
                     /locus_tag="ACN3HL_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HHC8006478.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            25656..26063
                     /locus_tag="ACN3HL_001606"
     CDS             25656..26063
                     /locus_tag="ACN3HL_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HHC8006479.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(26514..27023)
                     /locus_tag="ACN3HL_001607"
     CDS             complement(26514..27023)
                     /locus_tag="ACN3HL_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006480.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
     gene            27139..27506
                     /locus_tag="ACN3HL_001608"
                     /pseudo
     CDS             27139..27506
                     /locus_tag="ACN3HL_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9487 a         4099 c         5128 g         8814 t
ORIGIN      
        1 aaatggaacg ctcttcggct tttcggtgtc tactgaaatc aaggtattaa tgggaataac
       61 agcctaagat atttggagtt cagagagggc gcgtttgatt ttcaaacttc gcaacagaac
      121 cgagaacctt gggttttcaa gtgctttttg gttcattaat cttaaccata gtgtttttaa
      181 agtggaaaac aagcaacaaa aaaagtatgt ggagccttgt aggaatagtt cttattattt
      241 ttactgtgac tgcagcaaca gaagcaaatt attcgcataa aattcagtcg tataaaggtc
      301 gtttagttat gaccaaaaaa gatgttacac gttatacatc ctcaagaact ggaggcctat
      361 atgactatgc accattagat gcattgaaat ataaagatca tttaaagaaa catgaagtaa
      421 aagttggtga tcggtgggag aatgcatctc ataaagcata taattccaaa atagtctata
      481 cagtagaaga tgccgatgag caaaatatca cattacctgt attcaattat tggggaacag
      541 ttgtgaaagt aaatgggaaa aagagcacta tagaaaatga caatggttta gtgtctatta
      601 aaggtacggg gaaaagaact atagttgagg tttcatctac gtatccaact acgatgattc
      661 tatctttatt aattagttca ataactttta tattcttatt tacacgttat ttaataagat
      721 gctgcggtga aatgaaaata gattagatag atattataaa tatgttgatt ctattttcat
      781 agcaatggag aaaatacatt agcaatatat aaaagaaggt atcaagagtc acagtgaatt
      841 tattccgaaa agtgaaaaga gcaaatataa aatttaatga aaatatagaa ctaaatagga
      901 aaacgtagac gtaattttct acgttttcct tttcatatat attaaatatt acggaaaatt
      961 atataaacta atttagtgtt ttgtttgtaa ttcctaattt tgctccactt ttagataatt
     1021 tttaggtcta tttaactcat cagacattct atgctcattt ttctccaaat ttgtttcaac
     1081 tctttcgtac ttaattttgc gtatttgaaa attcttcttt tagagtactt ttattacgat
     1141 actagtatga tatatatcta tagcaaacag ttaaaatctt cctaaaataa gcgaatagca
     1201 ttcctaaaac ctataaaatt tttagatgaa gcgacaagtg gacaattaat aaactacttg
     1261 aacatgaaat tatggatcac ctttcaaatt tagaaaatgg aattcttata cttattgcgc
     1321 aacatttatt gattgcaaaa ttatgtgaca aaaaaaacta gtagaagaaa gaataatggc
     1381 ttgataataa agtactacct attaaaggta gtactttatt taatttagta taaattaaca
     1441 tactactata ttttaggttt catattatat aaattaataa tatactacca tttgttggta
     1501 gtataattta aaggtaataa gttattcttt tattactatg tttgggtttt atagcaaaga
     1561 aagtttaata agagtttgga cctagcaaac aatattaatg aggtcattaa atcttattat
     1621 ctttagtgat ataacgaaat atctacacag acaaaatgat agcgtaaaat attttgtgta
     1681 aatagatatt tagggtagaa aaaaagaaag tccattctgt aaaattaaag ttaccacaac
     1741 cgaaatttta taggaggact ttctcatgcc caattttact acagaaatta tggaaacact
     1801 aatcaataaa ggtgatttag atgaattatt tcgatgtcat ttagaattag ctgttaattc
     1861 attattgcag gctgaattaa cagcttttct tgattatgaa aaatatgatc gtgctgggtt
     1921 caattcaggt aattcccgta atgggaatta ttcacgttca ttcagaacag agtatggaga
     1981 attaaatttg gtaattccta gagatagaaa tggtaagttt tctcaacaaa ctttacctgc
     2041 ttataaaaga accaatgact ctttagaaac cactattatt cagctatttc aaaaaggaat
     2101 tactatgtct gaaatctctg aattgattga aaaaatgtac gggcatcact atacgccaca
     2161 aaccatttca aatatgacta aaatagtttc tgaagatatt attgccttta aagaaaggtc
     2221 cttagaatcc agatactctg tcatttttat ggatgctact cacattcctt taaaaagaca
     2281 aactgtttca aaagaagcag tttatattgt aattggcatt cgattagatg gaaccaaaga
     2341 ggttcttggg tttagtcttg ctccaactga atctgcttat gtttggaaag agattcttca
     2401 agacctaaaa gaccgtggtt taaaagaggt tttattagtc gtaactgatg gtttaagtgg
     2461 cattaacgat agtattcata gtgtttatcc aaatgctcaa tttcaacaat gttgtgtcca
     2521 tatatctaga aatatcgctc ataaggttcg tgttagtgat cgacaagaaa tctgtagcga
     2581 tttcaaatta gtttatcaag caagttcaaa agaagaagca aataatcaaa taaggtttat
     2641 gatagataaa tggaaaaagc agtatccacg agtggttaaa ttgctcatga atcctgctat
     2701 attaaccttt tataatttcc ctccgtcaat cagaagaact atttattcaa ctaatttgat
     2761 tgaaggtttt aacaaacaat taaagaaata taccaaaaga aaagagcaat ttcctaatga
     2821 agaatctctg gagagatttc tagtatctca attcaacaac tataatcaaa agtttctatg
     2881 ccgagttcat aaaggtttta aagaaataca tgatacatta gaatcaatgt tttaacttga
     2941 tcaacagaat gggcttttcc atttacacaa aattattgac gctcccgaca aaattatgat
     3001 cttgcgtaaa gttataaaat attaataaaa atattttatt aatgaaaagc ttggtagcac
     3061 ggttattcat atgctaattt atttcacttt atagtaaggg gagttcttag tatattgttc
     3121 aaacttaaat ttcatataat ttaattatgt aaattagcta ttctaagaac ttctacggat
     3181 aactgcccgt ctaaaattta aataagagct tagaatcttc atataagtaa ggttaatttt
     3241 tttgtacaaa aaagtcggaa tattctgagt tactgaaatg atataaaatc ataaactaaa
     3301 tcccttgatt ttattgactt tcaaaagttt atatatataa gttaatgatt atggtaaaat
     3361 atatacataa tcattaactc agaatatttt taagaaggga aacaatagtg agctataatg
     3421 tacaaccgtt aaggacaaat gaagagatac aagattttca gttttggcta agaagaacaa
     3481 gtaatccgga aagagatagt tttttatttt tgtttggaat caataatggg ttacgtatgt
     3541 cagatattat aggattaaaa gttggagata tacgaggcaa aagtaagcct attattgttg
     3601 aacataaaac aggtaagcga aaaccgattt ttatagataa tttgagagaa gaaattttat
     3661 tatatactga aggtaaagaa gaaaatgatt ggttatttcc gagtcggcaa caaggtcgac
     3721 atataacaag ggatcgtgtc tatcagatat atgcagatat agcagaaaaa ttaggacgag
     3781 atgatatagg aacacataca ttaagaaaaa cttttgggta tcactactac aagaaaacta
     3841 gagacattgc taccttaatg tttattttta atcatagctc gcaagcaatt acaaaaaggt
     3901 acattggtat aactgaagat gaaataggag catcacttcg tggatttaaa ctaggtgtat
     3961 aatttaaaaa tttttataaa cagtaaagac aaagattaaa agctattttt atctagaacg
     4021 attttatttc ataaagttcg cggaataaaa gctggggtta ctggtacttg gtataggttc
     4081 gtgttatata aactaagtaa ttaaataaca tttttaggtt ggaaaaggat gaaattaaaa
     4141 aaagagaatc aatacggtct caaaaacgca aacgctgcgg aataagaaaa atactgataa
     4201 ctcaacgttt agcagactat ctaataggga tagtctgctt ttttcgtttt tgaccatact
     4261 tttgaccttc tgcaaacttc cttgcttttc ctctgtagaa ctcatgaaat ctgcaaaacg
     4321 aattgccgtt tcctctgtct gctttttcgc gatatgggtg tatatatcat ccatagtggt
     4381 tttaatatct gtatgtccaa gtcgaacata cacttctttg acagacgcac cagattcaaa
     4441 gagcagacta caatgggtat gacgaaaacc atgaagtgtg atatgtttta agttattctc
     4501 tttaatgatg attttcaaat tgtgatttac atagtctaaa taaaggggct tattttcttc
     4561 tgatgaaaac aaaagttgtt caccatcttt tataggtttg attctcattt ttagatatta
     4621 tgcccgcacg tattcatcac atttctattg tgaatcgctt tattcgaccg acatttgact
     4681 tttatcataa tatactcggt ttaaaattac taatgaaaac aattaatcaa gacgatcata
     4741 ccatgtatca cctgtttttt tcagataatc accaccgtgt gggaactgaa ctgacttttt
     4801 ttgaagtaca agaagggaac aaccagtttt ttggaaccaa tacgattgaa cgaacgatac
     4861 taaaagttcc ttccgaagca tcattgcatt tttgggaaat atattttgaa acacaaggcg
     4921 tttgccatta tggaatcgaa tcattttctg gacgacctat cttacgtttt gaagggccag
     4981 atgcaacacg attagcttta gttcccttac gcgaatttga agatattgat gattatttcc
     5041 cgtatgtcac agaccagatc cctacagagc atgccatttt aggaattgat gccattcaac
     5101 tacgcgtaca atattccgat gcgactgaac gagagttatt gtcggtaggc tggtagcaca
     5161 aagaatacgt cagtttcttt tcgggtcatc aacgagtgac aatcttagaa aatcaagaca
     5221 ctcagttcta tcaagaagtt cagattattc aagatcgtga gaatccagtt gccattgaag
     5281 ggattggtag cgtccatcat gttgcgtttg gcgtagaaaa taaatctgat ttacaacgca
     5341 tcgacaaaca attacaagag cgcaatttta taaattcagg aataaaagat cgtgaatttt
     5401 ttgtatcact ttattatcgt gacccaaatc aattattgat tgaaattgct acaggggaag
     5461 gaaacctaga tgcaaaagcg tatgaaaatc aaagtccacg ctttgaagaa attcctttat
     5521 ttttaccgca gtacttaaat ttcattcgtg aacaagtgga gcaataatta gctaatcaaa
     5581 tccatgacga agagtaagag gttgactcat aagtcaaaaa ataaagaaaa acgcatcaaa
     5641 tccattctaa agaatgttga tttgatgcgg ttcctatttt tataaactat cattttcgac
     5701 taataaaact acttatgagt cagcctctct ttttttcttg atttttatac ctctttctag
     5761 gtaaactaaa catctgccaa aaataccgtg tctcattgaa acattctcaa ctatttcaaa
     5821 ataaagggga gtaccaaatg aacgagtata ttgaaattat ccacgcaaga gaaacaactt
     5881 aaaaatgtca gtctcaaaat tcccaaaaat aaaattagta tttttaccag cgtatctggt
     5941 tcaggaaaat catcgattgt ttttgatact attacccaag aagctggtcg tcaactgaat
     6001 gacacctatg atagttttac ccgtttattt ttacctaaat acagtcgtcc agaggttgat
     6061 gagattgata atctttctac ggcgattgtg gtcaatcaaa agaagattgg tggcagtgcg
     6121 cgctcaacgt tagggacgat tactaacatc aatgcgttat ttcgtgtgtt gttttcatgt
     6181 tttgcaacac ctagtttagg atatgcaaat gcttattcat ttaatgatcc tagtggaatg
     6241 tgttctgtct gtcagggaat cggtaagacg attgcatttt taataggatt gctttatttt
     6301 tcggctattg ataatgctga ttttgtattt tctgatccat ttaccgcaga agttttgtct
     6361 ggaattgagg aacaggcaaa gaatcatggt tattttgtat tggtgcataa tgttaattca
     6421 gcagaagatg ttaaaactat tcagagaaat tggcgttttg aggggttcat tgttgttggt
     6481 gtacgtgtaa aagaattttt ggaattaaat aacgtttttg atggtcctgt tgtttatatt
     6541 gatacgcatc tttcaaaaga gacattaaga gaacttgaac aacaaatgaa tcgtttattt
     6601 gtaaatacaa atgattacca agctagtaca ttggcagtgg aacatttgat tcattatggt
     6661 catgagaaaa tagcgtttct ttcttttgac tacattgtag gtgaaccaag tgttattcaa
     6721 gaacgacatc aagcttatat cgatacatta aagaaatatc atttaacctt taaatcgcat
     6781 tggatatata acaactctga atttgagcga atttatcaag aattagctga atttactgca
     6841 attgttgtta ctggagatta tttagcggct aaattagtaa aatttttaaa aaataagaat
     6901 aaacgagtga tggaacaatt atcgattatt ggatttgatg atattacttt tgcagaatta
     6961 atggatcctg cgttgacaac aatacgacta aatccaggta acaagggggc gattgctttt
     7021 caccaactga ttggactggc caaacaagaa gaaataaaaa atcaagtact actattagag
     7081 ggagaattga tttctcgaga ctctgttcac aaaatcaaat aaaaaagctc tgtgaaataa
     7141 gtatagttaa caataaaata tccgaacgat agagagaatg aactgtgatc tagcagttcc
     7201 tcgtcgcaaa ttcactagaa ttagcattat ttactctaaa ttgttcggat attttttctt
     7261 gtttttaatt atgattacag tgcctatttt taacgaaatt tgcttatttt caaaatgtat
     7321 gattatatgt tagtaaacac tttcaaatat gaaaagagga gctattatgg taggaattag
     7381 ggatgttgca aaacgggcgg gtgtgtccat tgcaacagta tcgcgcgtgc taaatgagga
     7441 tccgacactt tcagtaaccg atgaaaccaa acgaaagatt gcagaatcgg ttaattttta
     7501 tcattatgtc aaaaaaagtc ccgttgcaaa aaatttaaca aatattgcat taataacgac
     7561 agtttctgaa gtagatgagt tggaagatcc ctattttcga acgattcgca gagggattca
     7621 agtcgaagca gaacaaagca aagtcaattt gaagaaaatt attcgtttgt cagaaacacc
     7681 gttggagcaa gacgatttgc taaaatgtca aggtgtgttg attattgggc aggtgctatc
     7741 ttctgtgatt gaagaagtat cagcaattaa ttcgaatgtc gtagtgattg atgaccctag
     7801 tattgaagct gaagtagatg cagtttatac tgatttaaca aaagcaacga atcagcattt
     7861 agatcgattg tataaaaaag gacaccgaaa cattgcgttt atcggaggag gacgtgttcg
     7921 tttagatagc caaggaaata aacacgtgtc agatgatgat tatcgaaaaa tagcctatga
     7981 gacgtggatg aaacaaaaag gattagaaaa atatagtcaa atttatttag aaggctggac
     8041 cacacttgac ggaatgcagg cagcagattt acttttgaaa aaacatgcta aagataagtt
     8101 gccgactgct atcatggtag gaaatgatcc tattgctgtg ggggtttatc gttcacttca
     8161 aaaaaatggt ctacatattc cagaagatat ttcgattgtg agttttgata atattgaagt
     8221 tgctgaattt ttaacacctg cattaaatac ggtgaatgtg aatacagaag aaattggaaa
     8281 actagcagtt cgcatggtta atgaacgaat aaaagaagtt agaaatgttt cgatcaaagt
     8341 gattgtttct aataatatta ttgttagaga aagtgaaaaa aatatcgatt aaaaaagtaa
     8401 acatccaaaa aagggtgttt acttttttgt ttactaatat ttttagtaaa aaatctcgac
     8461 aaaacattaa gtaaacagtt atggtgttgt taacaaaaag aaaacgcatt caaaacagga
     8521 ggaattaaga tgaaacattt caaaaaaata gctttaacag ggatagctgt tttaactggg
     8581 acattactcg cagcatgtgg tgggggagat agtaattcta aagacgggca agtaacttta
     8641 agctatgcga gttgagatac tgaccaagct ccaggactaa gaaaaatgtt agatgaattt
     8701 gaaaaacaaa atcctgatat caaagtagaa atggagacaa cgccttggga tcaatattgg
     8761 gttaaattag aagctgcaac aacgggaggt aatatgccag atgtagtaac catgcactct
     8821 agcgaatcct ataaatatat gtcacagaat gctttgatgg gacttgatga tgttatcaaa
     8881 gaaaatgata ttgacatggg aaactttact gaaggaattg ctgatttcta tacgcttgaa
     8941 gacgaactat acgcaatccc taaagatgct tctgtagtgg ggctatggta caacaaagaa
     9001 ttatttgata atgcaggtgt cgattatcca gatgaaacat ggacatggga aacactcaga
     9061 caagctgcaa ttgatttaac agatgaatca aaaggcatct atggttttgc atcacatatt
     9121 ggaacagaga ctggctactg gccatttatt tatcaaaatg ggggagaagt atttgccgat
     9181 gacaatacaa aatcaggttt gaatacccca gaagcacaag aagctttagc tttttatcga
     9241 gatattgcac ttgttgatca tgcttcacca acaattacag aattacaaga tcctgataag
     9301 ttaagtcgtt ttcaatcagg tagattagca atgatgattg aaggaaactg gtttgcaccg
     9361 ggatttttga aaaatgacta tctagttgaa aatgttgctt ctgccgtgtt acctaaggga
     9421 aaagttaatg caacaattac aaatggactt ggttgggctg ccagtgcgag tacaaaatac
     9481 ccagaagaag tgaaaaaact aatggcattt ttagctagtg aggacgccaa taaaatccaa
     9541 gcggaaacgg gggcatcaat cccagcacta aaaggctttg aagacgagtg ggctgcttct
     9601 tcagatacaa ttgatttgag tgcttttgga aaaatgttgg agtatggagt ccctcgtcca
     9661 tacaataaag atggattacg agctgaacaa gcagaagttc aaattattaa ccgtattctg
     9721 tctggtgaag taactgttga agatggaacc gctcaaattg aaaaagaagt caatgcgata
     9781 ttgagcggaa attaaattag ttaattatac aatatacagg cgaaaggatt ctatttcgtc
     9841 tgtatattaa tggatgaata ccaaaaaggg ggatattatg aaaaatcgaa tttttggaaa
     9901 atatcgtaaa gatcaagtga tatggggcta tatttttatt tttccaacgg cattaggatt
     9961 aattttatta aatatatggc cagcaattca aacagcaatt ttaagttttc aaaaaacggt
    10021 agggttcggt gatactgaat gggtcggatt aagaaattac caaaaaatgt ttgcagacgg
    10081 tgaagttttt cagtctttat taaacacatt aatttatgca gtggtttcga tacctagtat
    10141 tgttgtatta tccttgttgg tggcagtttt aatgaataga aaagttaaag gattgtcgat
    10201 ttatcggaca atttattttc taccagtcgt tgctgcacca tccgcagtcg caatgatttg
    10261 gcgctggatg ttcaataatg attatggact gattaataac atgttggcta aaataggtct
    10321 cgatggacca gcatggttaa cggatccatc gattgcgatt tattctatta tcattgtagg
    10381 agtttggagt gctattggtt ataacatggt gttattacta gccggcttat aagaaattcc
    10441 taaaaattat tatgaagcag cggaaattga tggtgctagt ccaatccagc agtttttcaa
    10501 cattacgtta ccattagtta caccaacatt attttttgta gttgtaacaa cagttatcaa
    10561 tgctttccaa gtatttgatg ttatttttat gatgattact cctaatagta ccgccatgtt
    10621 taaatcacaa tcattagcct atttattcta taaacattca tttattttaa atgacaaggg
    10681 atatggttcg gcaatcgtta tgttcctttt agtgattata ttaattatta ctgcaattca
    10741 aatgaagttg cagaaaaagt gggtaaacta ttaaggaggc tatcaaatta tgaaaaataa
    10801 atttttttca aatgcgccaa tccatatcat gcttatttta ggtggtattg caatggcatt
    10861 accttttatt tggatgattt taacttcagg gaaaacgttg gttgaatcta cccaaattcc
    10921 acctacaatt ttccctgaga aatttcagct aagtaactat caacaagtac ttgatttatt
    10981 accattcatg gctttttata tcaatacatt tttaatggtt gttggacgag tgattggctc
    11041 ggttttattt tcagcaatgg ctgcatatgc ttgtgcgcgt ctaagttttc cagggaaaaa
    11101 tatccttttc agcttagtac ttattcaaat gatgattccc ggttccattt ttattactcc
    11161 acagtattta ttagcacaaa aattgggtat tttaaataca attccagcat taatattacc
    11221 aggggtagtt agtgcgtttg gtacgttttt attaagacaa tttttcttag gtttacctga
    11281 tgaattggag gaagcggcct atttagaagg tgccaatatt tggacgatct ttttcaaaat
    11341 tatgttgccg cttgctaaat caggattggt tgcacttgga atattcacag cgttgtttgc
    11401 atttaaagat ttaatgtggc cattgattgt caatacttca attgataaga tgcctttagc
    11461 tccgggatta gcaaacttac aaggacaata tgccacgaac ttcccacaat taatggcagg
    11521 ttcgttatta gcaatttggc caatagttgt gatattcatc gttttccaaa gaaaattcat
    11581 tgaaggaatt gctacaacag gtagtaaatt ataaaactat taattagtga ttggagagta
    11641 agtacatgac aaaaattaca tttattggtg caggaagtac tatttttgca aaaaacgtat
    11701 taggcgatgc gatgttaact ccaagtctac aagatgcaca tattgcattg tacgatattg
    11761 atgaaaaacg actaaaagaa tcaaatttaa tgcttaaaaa tattaataaa aattcgaatg
    11821 aaaatcgtgc tgatattgtt tcttattatg atcgcaaaga agcgttaaga gaggctgatt
    11881 ttgttatcaa tgctattcaa gtgggtggtt ataaaccttc aacagtgatt gattttgata
    11941 ttcctaaaaa atatgggttg cgacaaacta ttggtgacac catggggatt ggtgggattt
    12001 ttagaaccct acggacacta ccagtaatgt tagactttgc taaagaaatg gaagaagttt
    12061 gtccaaatgc ttggttattg aactatacaa atccgatggc gatgttaacc atgggtgttt
    12121 taaaagcgac gagtattaag actgttggtt tatgtcatag cgttcaagta tgcgtaccag
    12181 aattgtttga gcatttagga atagccgatc aatatgactt aaatgacttt caatggaaaa
    12241 ttgcaggcat taatcatatg gcattcttgt tggaaattac aaaaaatggg gaagatttct
    12301 atccaacaat tcgtcagtta gctgcagaaa aaccaaatcc acatccagat tctgtacgtt
    12361 ttgaattgtt gaaacgtttt ggttactata ttacagaatc aagtgaacac aatgcagaat
    12421 accatccata ctttattaaa tcaaaatacc cagaattgat tgacgaatta gggattccgt
    12481 tggatgaata cttacgtcgt tgtgaacaac aaattaatga ttgggaaagc atgcgagagg
    12541 acattgtaaa taatggggag ttaacacata cgagaagccg tgaatatgct tcatatatca
    12601 tggattctat tacgacagga actccgtcag tgattgcagg aaatgtctta aataaaggct
    12661 taatcacaaa cttaccgaca gatgtttgtg tggaagtacc ttgtttagtc gataaaaatg
    12721 gcgtgcaacc aacctatgtc ggtgaattgc caacacaatt agctgcttta aatcggacga
    12781 atatcaatgt tcaagaactg acagtagaag ccgctttaac actagataaa tcaaaaattt
    12841 atcaagcagc gtatttagat ccacatctat catctgaatt gtctttaaca gatatcaaaa
    12901 atttagtgga tgatttaatc gaagcacatg gggactattt acctgaatat aattaaaaag
    12961 aagctgaaag agtaaggaat tttcaattcc ttactctttt cttagttaaa tttagtaaaa
    13021 atattgacaa aacacttagt aaacagttac attagtgtta acaaaaagaa aacgcattca
    13081 aattgtataa ggaggagcat aaaatgaagt ggtctaaaaa aattatttta gcttgtatag
    13141 cactaggagc aacgatctct ttgactgctt gtggaaaaaa tcaggaagat gcaagcggta
    13201 aggtagaaat agagtttttt aatcaaaaaa aagaaatgac tcaaacgatt caggagattg
    13261 ctaaagattt tgaagcaaaa aaccctgata ttcatgtaaa agttgtggat gtaccgaatg
    13321 ctggtgaagt aattaaaaca cgtatgcttg caggcgatgt accagatgtc attaatcttt
    13381 atcctcaaag tatagaattg aaagaatggg cgaaagctgg ttatttagag gacttaaccg
    13441 aagaaccgta tttagagaat atcaaaaatg gatatgcaca acgttttgct attgaggatc
    13501 gtgtatatag cataccatta accgctaatg tctatggttt ttactataac aaaactgctt
    13561 ttgaggaaat ggggattcaa gcaccagaaa cttgggcaga atttgaaaaa atagtagctg
    13621 agattaaaga tcaaaacaaa gtaccgtttg cgattgcagg agcagaaggc tggactttaa
    13681 atggttatca ccaactagct atagcgactg ctgctggtgg tgaagaggaa gcgaacaatg
    13741 tttggcgttt ctcagaagtt aatggaatta atgctgaaag caaagaaatg caaaaagatt
    13801 ttaatcgatt agatttgtta agagaaccaa aagctttgca aaacaactgg caaggtgccg
    13861 gttataacga tacagtagtt acttttacaa aaggtgatgc gttgattatg ccgaatggtt
    13921 catgggcaat gccgatgatt cattcacaaa atccagattt tgaagtagga acttttcctt
    13981 ttccagcaga tgaagcaggt caaagtctaa cgattggcgc aggagaccta gccttatcag
    14041 tttctgcaac ttctcaacat aaagaagaag ccaaacgttt tgtagaatat atgacaacac
    14101 ctgaagcgat gcagaaatat tatgatgtag atggtgcacc gtgtgctgtt gagggcgtta
    14161 tcgagaatac tcaggattca ccattaagtg gtttaactga acttgctttt actgatcgtc
    14221 atttagtttg gttagccaaa gattggaata gtgaaaatga tttttatacc ttaacaacaa
    14281 attatttaca caatggcaat caaaaagcca tgattaacgc attaaatgct ttctttaatc
    14341 caatgaaagc tgacggaagg taggaaaata aaatgaaaat aaaagaaatt ttaaatcgtt
    14401 actgggcaat catttttgta gcaattccaa ttattttgca gatgattttt ttctactttc
    14461 caatggttca aggtgctttt tacagtttaa ctaattggac tggtctgact tataattttg
    14521 attttgtggg tttgaacaat tataagattc ttttttctga tccgaagttt atcaaatcga
    14581 ttggcttcac tttaattgtg acgctttgca tgattgctgg acaaattggt tttggtattt
    14641 tgattgcgcg ggcgttgaac gcaaatatta aagggaaaac attctttaga gcatggttct
    14701 tttttccagc ggtcttatcg ggcgtggttg tttctttagt atttaaacaa atttttaact
    14761 atggtttacc aaaaattggt agtatgttag gcattgaatt tttacaaacc agtcttttag
    14821 gaacaacatg gggagcgatt tttgcagtaa tttttgtttt actttggcaa ggaattgcca
    14881 tgccagtcat cattttctta gcgggttttc aaagtattcc acaagaaatt attgaagctg
    14941 ctagaatgga tggggcgaat gataagcaaa ttttttggaa tattgaaatc acctacttat
    15001 taccaagtat ttcaatggta tttattatgg cattaaaagg tggcttaaca gcatttgatc
    15061 aaatttttgc tttaactggt ggtggaccaa gcgatgccac aacatctttg gggttacttg
    15121 tttataatta tgcttttaaa aacaatcagt ttggttatgc gaatgctatt gctttagtct
    15181 tatttatctt aattgggatt gtttcactgg cacaattaaa attatcgaaa aaatttgaaa
    15241 tctaggaggt ttcccaatga aaacatcaaa agaaaaaaat atttctaaat acttgctttt
    15301 attattaggg ggcttcatga ttttagttcc cttagtttca acgctattcg gttcatttaa
    15361 aacaacaccc gatattatga ataatttctt tcgttttcct aatccagcga ctttggaaaa
    15421 tttccgaaga ttgttagcgg atggaattgg tcattacttt tggaattcgg caatcatcac
    15481 aatcattgca gtagttgctg tgacagcaat tattcctatg gctgcttatt cactagcaag
    15541 aaaaatgact cgtgggaaag catacggatt gatgtattta tttttaattt taggaatttt
    15601 tgttcctttc caagtaatta tgattccgat taccgttatg atgagtaaaa ttggtttagc
    15661 aaatatgtgg ggattaatct tactctatct cacttatgcc gtaccacaga cactattttt
    15721 atatgttggt tttattaaac taaatgtgcc tatcagtctg gatgaggctg ctgaaattga
    15781 tggggctagt cactttacaa cttatttcaa aattgttttc ccaatgttaa aaccaatgca
    15841 tgcgacgact attattctta atgctctatg gttttggaat gatttcatgc taccattatt
    15901 aattttaaat cgtgattcta atatgtggac actaccattg tttcaatata attatacggg
    15961 acaatatttt aacgactatg gtccaagttt tgcttcctat acagtaggaa ttgtcacgat
    16021 tacactagtt tatcttgctt tccaaagaag tattatagct ggaatgagca atggagcagt
    16081 gaaataacca ataaattatt ctcattataa aggagttcat aaacttatga ttatatttga
    16141 caatcacaca caaacatttc atttacaaaa taaaaaaatt agctatctat taggaatcga
    16201 agaaaataat tatttaacgc atctttattt tggaaaaaag attacgcact attctggtgg
    16261 gtatcgctac ccccgaacag atcgttcctt ctcacccaac aatgcaaatg cgcaagatcg
    16321 tttattatct ttagacacat taccattaga atttccagga tatggacatg gtgattttag
    16381 agaaccggcg cataatatta aattaggaaa cggtagtcgt gtaaatgatt ttcgttatga
    16441 tagctacgaa attcaaaaag gaaagcccag cttagcggga ttgccagcct tatatacgga
    16501 agatgatgat gaagctgaaa cgctgattat tcaattgaaa gacgcgatta gtggattgac
    16561 tttacagttg ttctacacaa tttatcaaaa tcacagtgta attattcgtt ctacgcaatt
    16621 agtaaataat agtgatgaaa cagtggagat taaccgctta gctagtcaat caattgattt
    16681 tccaaatcgt ccactcgagt taattcattt aaatggtacc tgggcaagag aacgtcaaat
    16741 gactagagaa aaaattcata cagggataaa agtattagat agtaaacgcg gatcaagcag
    16801 ccatcaacaa aatccgtttg ttgctttagt agatgccaaa acagatgaat ttcaaggaga
    16861 ggcatatgga tttaatttag tttatagcgg taatcacgaa acggtgattc aaaaagatcc
    16921 atttgaccaa acacgggtca ttatgggaat taattcattt aattttggtt ggcaactaaa
    16981 aactggcgac tcatttcaaa cgccagaagt cgtgatggtt tatagtaatg aaggtctgaa
    17041 tacgttatca cagacgtatc atgaattgta taatcaccgt ttaattcgtg gaaactatcg
    17101 tttaaaagaa cgtcccacgt taatcaacaa ctgggaagca acgtattttg attttaacga
    17161 agaaaaaatc atgaatattg tcgatgatgc gaagaacttg ggcattgaaa tgtttgtttt
    17221 agatgatggt tggtttggcg gtcgtgaaaa tgacttcact tcattaggtg attgggttga
    17281 aacagaaggc aaacttgctt gtggtttgga aaatttagcc aagcaagtgc atgataacgg
    17341 gatgaaattt gggatttggt ttgaaccgga aatgatttct gaagatagtg aactatttcg
    17401 agcacatcca gattgggcat tgggtattcc aggtcgtgac cgctcaatta gtcgaaatca
    17461 atatgttctt gatttttcaa gacaagatgt tcgtgataat atctatcaac aaatgacggc
    17521 gatttttgat cgtgtaccga ttgattatgt gaagtgggat atgaatcgaa atatgacaga
    17581 agtctattct gtcttgttgg actcaacgat gcaaggtgaa gtggctcatc gttatatgtt
    17641 agggttatat gaatttttag aaaagttaac aacgaattat ccaactattt tatttgaaag
    17701 ttgttcgggt ggaggcggtc gttttgatgc aggtttcttg tattacatgc cacaaacttg
    17761 gacgagcgac aataccgatg ccgtggctcg tctgaaaatt caatatggaa ccagcttagt
    17821 gtatccaatt tcaagtatgg gtgcgcatgt ttcagcagtc ccaaatcatc aaacaggaag
    17881 agaaacgagt ttaactattc gtggcaatgc tgcgatggct ggtgtttttg gttatgagct
    17941 agatctaacg caattaactt ctgaagaaaa agcagaaatt aaagaacaag ttgcctttta
    18001 taaaaagcat cgccaacttt tgcaatatgg aactttttat cgcttggaaa gtccgtttga
    18061 aggcaatgat actgcatgga tgtttgtctc aaaagaccaa acagaagcca tggtctttta
    18121 tttccgagta ttagcagaag ctgcgcatcc attagtcaca ttgaaattag caggattagc
    18181 agaagaagca acttatcaaa tggaagatgt aacatttgct ggcgatgaat tgatgaatct
    18241 cggtttttat attgactcag aactacatgg tgattatgcg acacaacgct tttatttgaa
    18301 acagatatag tagcttgaat ttacaatata agtgcaacac caaaagagac tcattccaaa
    18361 cgaagaaaat atgttttatt tacacgcatt tactaaaaag cagcctgatt tgaattggga
    18421 aaatgaagaa gtacgtgaag aaatctatgc aatgattaac tattggttag ataaaggact
    18481 aggcggattt agaatcgatg cgatattaaa catcaaaaaa aaactagagt atggcatctt
    18541 tgaatctgat ggagaagatg ggttagcctt cattgggccc tggattctta atcagtcggg
    18601 cattgaagtg tggttaaaag aaatgagaga gcggacattt aaaccacata atagtatgac
    18661 ggtagcagaa gccgatgttc ctaatgaacg tttagatgaa tatattggtg aagatggcta
    18721 ttattcgatg gtttttgatt ttagttatac ggatattgat gtacctgaaa ctggtgaatg
    18781 gtttaaagat agccaatgga catggacgga tatgcgtacc aatattttta cgaatcaatt
    18841 agttacgcaa gataaaggtt ggggcgcctt atatttagaa aaccacgatc aaccacgttc
    18901 aattaataaa tatattccag aagaatggat caatgattat agtaaaaaaa tgttggcgac
    18961 gctttttatg ttactaagag gtaccccttt tatttatcaa ggacaagaac taggaatgac
    19021 caacatagaa atggcatcat tagaagattt tgatgatgta gctacgcatt ctcagtataa
    19081 acgggcatta gaatatggat tggcaccaga gcaagcattg aaagctgtca ataaacgaag
    19141 tcgggataat tctcgcacac ctatgcaatg gaatacgcaa aaaaatgcca gattctcaac
    19201 ttctgataat gtatggttaa aagtaaatcc taattatcca gaactcaatg cagaagctca
    19261 gttaaccaat caacagtcgg tattcaatta ttatcatcaa ttaattaaat taagaaaaaa
    19321 tagtgtatac aaagacgtgc taatctacgg acaatttcta ccagtgaaag ataaaaatga
    19381 acatattttg ctttatgaac gccaattaga agataaaatc gtattagtta tcttaaacgt
    19441 tacagcaaca gaacaagaat attatgtaga tgaacagtac caacaagtat taatcaataa
    19501 ttatgaagat gttttattag atcaaagtcg aaaattgcgt ttacgaccgt ttgaaagtat
    19561 tgtattagct aattatggag gacaattatg aaaattaaaa acgaagcaat gctcatcacc
    19621 tatgcagata gtttaggaaa aaacatgggc gaattaaaac aagtcttaga caaacattta
    19681 caaggtgtta ttggtggtgt acatctgttg cctttttttc catcgacagg tgatcgaggc
    19741 tttgcgccga gtgattatac gacagttgat ccagctcttg gaacatggga agatgtggaa
    19801 gcattaggtg aagattatta tttgatgttt gattttatga ttaatcacat ttctcgtgaa
    19861 tcaaaatttt tccaagattt caaaaaaaac catgagcagt caccatacaa agaaatgttt
    19921 atccgtattc atgaattttt cccagaaaat cgaccaacac aagaagatat tgatttaatc
    19981 tacaagcgta aagacaaagc gccgtttcaa acggtagaat ttgcggatgg tacgacagaa
    20041 gaggtttgga atacctttgg ggaagaacaa attgatttag atgtgaccaa agaagttgtg
    20101 aaagaattta ttcgagaaac catcaaagat atggcgaacc atggctgttc tttaattcga
    20161 ttagatgcgt ttgcttatgc gattaaaaaa ttagatacca atgatttctt cgtggaacca
    20221 gatatttggg aacttttaga cgaagtgcgt caagaagcag cgaaatatga cgtcgaatta
    20281 ttaccagaaa tccatgagca ttattccatt caaatgaaaa ttgccaatca tgattattat
    20341 atctatgact tcgccttgcc aatggtcact ctgtattcac tttatagtgg aaaatcagaa
    20401 cgtttagcca attggttgaa aatgagtccg atgaagcagt ttacaacatt ggatacgcat
    20461 gatggaattg gtgttgtgga cgctcgtgat ttattaacag atgaagaatt ggattacacc
    20521 tctgaggaat tgtataaagt cggggcgaat gtgaagaagg tctattcaag tgccaattac
    20581 aataatttag atatttatca aattaacagc acctattata gtgcattagg cgataatgac
    20641 cgtagctatc tgttagcacg tgcgattcaa gtatttgcgc cagggattcc acaaatttat
    20701 tacgttgggt tattagcagg aaaaaatgat attgaactgt tggaagcaac gaaagaaggg
    20761 cgtaatatta atcgtcatta ctatgattta gccgaaattg aagaagaagt gcaacggcca
    20821 gtgattcaac aattatttgc acttttaaaa tttagaaatg aatctgcggc gtttgatttg
    20881 gatggaacga ttgaagtagc aacgccatca gaatcagaaa tagtgattac acgtaaaaat
    20941 aaaaacggta gtgatagtgc aacattaacg gctaacttgg atacgaaaga atttatcatt
    21001 gagtctaaag atataaaaat tttcactagt gttgcattaa aattttaacc tattccatag
    21061 aacaaaaaat cctttatact agcacttgga tgacttatcc aagaccaata aaaaggactc
    21121 atacatggat aagtataaaa caaatacagc atttaataaa tggttttctg ccataaaatt
    21181 aggaaaactt tctgtcaact cccaaaaatg tatttttgat tacaattcgt atcgtaaaaa
    21241 actgtctttt gaagctgtgc tcaagctctt tctctacgca gttaatgaag aaaaagaaag
    21301 tttgcgtgat ttgagtacag ctcttatcga ccgatcgctc caactagaaa ccgatgtgtc
    21361 atcgattagt catacccaat tgtctcgagc atttaatgca cttgaaccta aagtgttaga
    21421 agaaattttt caacaactgt tagaaaaagt tcaacatcaa atcaaaccaa ccaagcgaaa
    21481 tcatctgtat ctgattgatt ccagtacgtt ttcgcttagt ttaaaacgtc ataagtgggc
    21541 gactttccgt caaacaaaat caggtgtcaa gttacactta aactattgtt atatggacga
    21601 tactacgatg tatccaactg attttacctt aacaaatgcc catgaacatg atctcaatca
    21661 actaccagta ttggtgaatc aaccagaggc aacttacgtg tttgatcgtg ggtattagga
    21721 ctttgaaaag atggatcaga tgcattggga tggctatttc ttcgtcactc ggattaaaaa
    21781 aaacaccaaa gttcacgtga tagatactct ggaaacatcg ccagaaacag aaattctacg
    21841 agacgagctg gttcgtttag gatctaaaac ctatctaacc gccaatttcc gactagtcac
    21901 tgttcaagat aagaacggac gtgtgtttca atttatcacc aatcgaatgg acgtctcttc
    21961 aaaagaaatc tctgatatgt atcacgctcg ttggcaaatc gaattgtttt tcaagcacat
    22021 caaacaacac atgaccatta aaaccttctt ttctcaaagt gaaaaaggcg tgcagaatca
    22081 attgatttta acgatgattt ccgctctcct cacgtttctc atcaaattgg agacgaaaac
    22141 ggaaaaatca gtgttccaaa tcaaacgatt ctttcgttat ttactgtttc agccctttga
    22201 atgttgtcta gaaaaattaa ttcccacatg agaaaaaaga aatttggctc gttacttttg
    22261 gttttcagtt gaataacaga taaaaaattt tctggaaaaa gtcatcctct gcgtcagcac
    22321 agtttttttt gacttatttt cagaggaaat agttttcaga atattctaaa atgttttatg
    22381 caacactagt gatatttttt agaattagat ttctaatgtg cattttttga gtattaagga
    22441 gcaagtatac aaagatttat aaagctgatt aaatttgaat aaaaatatgc aggaacgcta
    22501 ctatttttag tagtgttctt ttttatattt gaataaaaaa tgtggtggtt aaatggtggt
    22561 tataacaaaa aatgaattaa tgaaattagg ttatgggaag tatcagtctg agagaatcat
    22621 acgacaggca aaagcaatta tggtttcaaa aagctatacc tattacgaaa atagaagatt
    22681 aggactagta cctgttgaat ctgtagaaga agttttaggt atgaagatag aggtagagga
    22741 ggattttcag aatcatggtt aattttaaaa aagataaaaa tgggaaatat cattttactg
    22801 ctagtttggg attcgacaaa cgaacaggga aaagagtaca aaaaaacgta gaggggttaa
    22861 aacagttaaa gaagaaaaaa agcgtatacc gaacttgttt ctaattatgg aaaagaagca
    22921 gaaacttctc aaagtactat gttgtttgag gagttttttt ataaattatt cctaccttat
    22981 tatcaaggga aagtagaaga aagaacatat aaaaatcggt tatctacaat caaaaaaact
    23041 tttcttattt ctttaaaatg gagttaagag aaatacgtcc aattgacatt caaaagtggc
    23101 aaaataattt attgagcaaa tataaaaatt cttatgtaag aaacatgtat gggatttttc
    23161 agatgtcatt agatcgagca gttgttttgg gactacttga aaaaaatcct gcaaaagtta
    23221 ttggaaatgt gaagaaaagg aaaactacag ttgatttttg gacaaaagaa gaatttacaa
    23281 aagttatttc aactttttat attgatgatt tgtaccaaca ttttggtttt atttgtatgt
    23341 ggttactttt tatgaccgtt atgcgtttgg gagaagccac tgcattaact tggaaagata
    23401 ttgattttga aaataaaaac ttgcgtgtga ataaaacact ctattataag agagccaaaa
    23461 cctatgagtt tgtagaaccc gaaacggctt ctagtattcg tacaatcgaa ctagacgaca
    23521 atacaattac ctttttaaaa gcttggaagg agcgtcaagt ttcaatagga ggcatgtcgt
    23581 ttgtactttc ttataatgga acacctactc agaaatatac aatccgtcat attatgagaa
    23641 gacatgcaac gatcgttggt gttcatataa tccgcataca cggattaagg catagtcatg
    23701 cttctttgct tatatcacaa taaaaagatg cacttcgaat taaagaaagg ttaaaacatg
    23761 ctgatgtaca aacgacttta ggaacttatg gtcatttgta tctaaattca ttgagagaga
    23821 taacaaatga tcccacagat tatatccaaa ctaatttttc taaaatcaaa ccgacaccta
    23881 tttacgataa taaaaaataa atgataaaca aaagtaggat cacaccaaaa gaaacacact
    23941 agaaaaacta taatacaggc ttttctagcg tgttgtttct tatttccgcc tatttataca
    24001 ttatactcat aaagcattta atgcatcgat cgtagccgca ttgtctatat gggtatataa
    24061 agttgttgta ttggtacttg aatgtcccaa ttgttgggca gttaatacca atgaatttgt
    24121 ctgttggtag agtctagtag ctaatgtatg acgcagtttg tgagggctga cttgaattct
    24181 aaagcctttt gaatattttg ctaccatccg ttcgattgca ataccggata tacgcttggc
    24241 ttctccttgg taaattgcta gaaataaagc tttttcgttt tctgttactt tatatcgttc
    24301 tttccgaata gctagataat tagctaaata ttccattgcg aatgctgcta tattgacagc
    24361 atctctttta tttccttttc tagttactac cacattattc ttatctaaag ataggtcatc
    24421 taaattaata tttataacct cggagagtct caatccagat cctaaaatca gtgcattgat
    24481 cgccaggtct ctttctacat ctcgttgata atagatcaaa gctcgtttac tcaaagtatt
    24541 tttatattca ttggcaatat aatctagata attttgtgta tccttatcta gaaataattt
    24601 tttctcaatg gcattggcac gtgcagctaa cgtagtttta tctgtgatgg ttgctacttg
    24661 atccatagga ttattgtcta agtatggttt tcctagagga ttattggaac ttttcgaaag
    24721 atatttaaat agaaccttta atgccgtgat atttctattg atagtagaag tagatagacc
    24781 taagttatta ttatctttga gcttagtttt tgttgtctct ttttttacat tttcttttgt
    24841 gcgacgtttc aaatgagatt tgtacaagtt taggtcatag gcagttaact gtcttatcga
    24901 ggtgatagaa gtatcaggaa cgatagactc actcagaagc cattcataaa agagcttata
    24961 attttttaga tattctaaag tggttcgagg tgattgatct ttatcctcac gatcttgaac
    25021 aaaatctttt atataatcgg gcatatgaag tatgattgta tctatttttt gatatatttc
    25081 tgtatttttc atgtcattca tcctttcaat aagtagggga gaagagtatc tctataattg
    25141 gactatacca attatagaat gttttgtcaa ttggtatgct ctaaaattta ttaatttgtt
    25201 tcaaaaaaag catataaaca ggtatacgtt taataattta aaataaatgg tatacataaa
    25261 tagggaagga aatagaaggg agcaatctaa attttttgaa ttttcttaat taattatata
    25321 gaaagaacaa tctttctata gagttagaca tgagagggac tatgcttgat ttaaaatcaa
    25381 caagcgtata tactgtatat acaaagaaaa aggagggaga agactatggc aattaaagaa
    25441 agaaaattta gggaagtggg gaactcagta gtattaacta tttcaaagga gtttcttaaa
    25501 gaaaatgggt taaatcccgg agatacggtt tttttagatg aagaaaaact tcgagcggca
    25561 attacaaaaa aacaagcctt atctgatgaa attgatttag caatatctca agcattaact
    25621 gaatatgata ctacttttag agagcttgtc gataaatgag tattcattac ctagaagcca
    25681 aagatattat aaaaatgaat gtaatccaaa taaaaaaata ctctcctaat gaaccccttg
    25741 gtgtaaagga tgcgaatgct ttagaaatgt gtgtagggca acttcgagcc tcagcttttg
    25801 gtgaagaggt ttatccttcg atttatgaaa aagcagctat cctacttata caattgataa
    25861 agaaacatcc ttttcacaat gcaaataaac gtactgcttt cttagctact tttgtctttt
    25921 tgaaaatcaa tggacagctt ttagctattg atcaaaaaga tgctgtaaat ttagcggtat
    25981 atattgctac gtatgataag gatttcgatc aactaaaata tgaagtgatc aacactataa
    26041 agacacatac gcagcccatt taaggagtta ctgtatgtgt ctttataggg ttattagctg
    26101 ctatagcgaa ataattgaag taaattacaa atagctataa ttcaaatcca actatataga
    26161 aaacgtaaat tttctatata cttggatatg ctggaatgtt taagagaata attacatttc
    26221 tagaaaatac aataaaaatt acaggataat tagccatatc ctacctcctc tagcagttgc
    26281 tcaaaagtta gcactaagta acttcttttt tgttgctggt aacaatttat caatactaaa
    26341 atagcgttta agtatctaat aaatactaat tttaaagctc ttaattatta tgaaacacga
    26401 tataacaata ttgctatatc gtgctattgt aatattatac atttgaagac agcgtattct
    26461 tgttctaata tcaggaattt tttataaata tcagtcatat taagactcaa aatttattgg
    26521 tatgttcctc tgtatagagt ttgaccgtct accattatat agcaattatt atcattgttg
    26581 tcttgcacca atataccgtt aagggtagca ctaggagtag taacaatcac tggaaactca
    26641 tgagaaagct cggtcatttt tcctgttctg ctagaatcgt gttctattgt caagccattt
    26701 actataaacg tgaatacttt acttcctatt gttatagtag ctttttgaga aacagtttct
    26761 gtagctggag ctgtgcttct ttccgaattt gttagggttt cactggattc attgctataa
    26821 acaattgtag aggattctac ggcttcttga gtgtccacgt tggtgctgct agcttcatct
    26881 agcttccttt tgtattgttc gttactgatt gctaagcttt cccgttggtc atcaagctta
    26941 ttcatttctg taatggtata aaataatcct cctgctagtg ctatattaac aactaaacta
    27001 accgcaaata ataccttttt cattcttcct tctcttcttt ctctttttgt aattccttac
    27061 ttttggatag gctacaatta actagacaga aaaattaagg tgtgtagact agaagaaaac
    27121 ataccaggag gaatttttat gtctaagaga acacgaagaa ctttttcaca agaattcaag
    27181 caacaaatcg tcaatcttta cttagatgga aagccacgtg tagaaatcat tcgagaatat
    27241 gaactaacgg cttcagcatt tgacaaatgg gtaaagcaat ctaaaacgag tggttcattc
    27301 aaagaaaaag ataatcttac gcctgaacaa aaagaattgt tagaactacg taaaagaaac
    27361 cagcaattag aaatggaaaa tgatatttta aagcaagcag cgctgatatt cggacgaaga
    27421 gacaagtaat cgatgcgaat aagcatcttt accctatatc agcgatgtgc agaatattag
    27481 gtctatcacg tcagtcctat tattattaat caaaaccaaa gaaagacg
//
LOCUS       DBGZHO010000033        27488 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.033, whole genome shotgun sequence.
ACCESSION   DBGZHO010000033 DBGZHO010000000
VERSION     DBGZHO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.033"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(45..1511)
                     /locus_tag="ACN3HL_001609"
     CDS             complement(45..1511)
                     /locus_tag="ACN3HL_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HHC8006481.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="ACN3HL_001610"
     CDS             1898..2494
                     /locus_tag="ACN3HL_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHC8006482.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="ACN3HL_001611"
     CDS             complement(2552..3034)
                     /locus_tag="ACN3HL_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006483.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="ACN3HL_001612"
     CDS             complement(3140..3337)
                     /locus_tag="ACN3HL_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006484.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="ACN3HL_001613"
     CDS             3632..4390
                     /locus_tag="ACN3HL_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HHC8006485.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="ACN3HL_001614"
     CDS             4450..4878
                     /locus_tag="ACN3HL_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006486.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="ACN3HL_001615"
     tRNA            4924..4996
                     /locus_tag="ACN3HL_001615"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="ACN3HL_001616"
     CDS             complement(5146..5517)
                     /locus_tag="ACN3HL_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HHC8006487.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="ACN3HL_001617"
     CDS             5732..5917
                     /locus_tag="ACN3HL_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006488.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="ACN3HL_001618"
     CDS             complement(6000..6188)
                     /locus_tag="ACN3HL_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006489.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="ACN3HL_001619"
     CDS             complement(6212..6475)
                     /locus_tag="ACN3HL_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006490.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="ACN3HL_001620"
     CDS             6633..6890
                     /locus_tag="ACN3HL_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HHC8006491.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="ACN3HL_001621"
     CDS             complement(6961..7152)
                     /locus_tag="ACN3HL_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006492.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="ACN3HL_001622"
     CDS             complement(7293..7613)
                     /locus_tag="ACN3HL_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006493.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="ACN3HL_001623"
     CDS             complement(7636..8070)
                     /locus_tag="ACN3HL_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHC8006494.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8405..9043
                     /locus_tag="ACN3HL_001624"
     CDS             8405..9043
                     /locus_tag="ACN3HL_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHC8006495.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9367..9450)
                     /locus_tag="ACN3HL_001625"
     tRNA            complement(9367..9450)
                     /locus_tag="ACN3HL_001625"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9414..9416),aa:Leu,seq:cag)
     gene            9978..10478
                     /locus_tag="ACN3HL_001626"
     CDS             9978..10478
                     /locus_tag="ACN3HL_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006496.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10668..11012)
                     /locus_tag="ACN3HL_001627"
     CDS             complement(10668..11012)
                     /locus_tag="ACN3HL_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HHC8006497.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11166..12086)
                     /locus_tag="ACN3HL_001628"
     CDS             complement(11166..12086)
                     /locus_tag="ACN3HL_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8006498.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12273..12764
                     /locus_tag="ACN3HL_001629"
     CDS             12273..12764
                     /locus_tag="ACN3HL_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HHC8006499.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12788..15163)
                     /locus_tag="ACN3HL_001630"
     CDS             complement(12788..15163)
                     /locus_tag="ACN3HL_001630"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HHC8006500.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            15489..16115
                     /locus_tag="ACN3HL_001631"
     CDS             15489..16115
                     /locus_tag="ACN3HL_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHC8006501.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            16138..16842
                     /locus_tag="ACN3HL_001632"
     CDS             16138..16842
                     /locus_tag="ACN3HL_001632"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHC8006502.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            17034..17867
                     /locus_tag="ACN3HL_001633"
     CDS             17034..17867
                     /locus_tag="ACN3HL_001633"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HHC8006503.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            18064..19992
                     /locus_tag="ACN3HL_001634"
     CDS             18064..19992
                     /locus_tag="ACN3HL_001634"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HHC8006504.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            20130..20585
                     /locus_tag="ACN3HL_001635"
     CDS             20130..20585
                     /locus_tag="ACN3HL_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HHC8006505.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            20665..20793
                     /locus_tag="ACN3HL_001636"
     CDS             20665..20793
                     /locus_tag="ACN3HL_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006506.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            21055..21324
                     /locus_tag="ACN3HL_001637"
     CDS             21055..21324
                     /locus_tag="ACN3HL_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006507.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            21724..21978
                     /gene="rpsT"
                     /locus_tag="ACN3HL_001638"
     CDS             21724..21978
                     /gene="rpsT"
                     /locus_tag="ACN3HL_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HHC8006508.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(22067..23113)
                     /gene="holA"
                     /locus_tag="ACN3HL_001639"
     CDS             complement(22067..23113)
                     /gene="holA"
                     /locus_tag="ACN3HL_001639"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HHC8006509.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(23151..25424)
                     /locus_tag="ACN3HL_001640"
     CDS             complement(23151..25424)
                     /locus_tag="ACN3HL_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HHC8006510.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(25417..25956)
                     /locus_tag="ACN3HL_001641"
     CDS             complement(25417..25956)
                     /locus_tag="ACN3HL_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HHC8006511.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(26092..26310)
                     /locus_tag="ACN3HL_001642"
     CDS             complement(26092..26310)
                     /locus_tag="ACN3HL_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HHC8006512.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(26307..26552)
                     /locus_tag="ACN3HL_001643"
     CDS             complement(26307..26552)
                     /locus_tag="ACN3HL_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HHC8006513.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(26668..27396)
                     /locus_tag="ACN3HL_001644"
     CDS             complement(26668..27396)
                     /locus_tag="ACN3HL_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HHC8006514.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         8523 a         5352 c         4680 g         8933 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg tggatttgtc ataaattgtc atgcttcttt tacctatgaa atattttcac
     8341 gtgttaaagt attcctcgtt gaacacaaca aataaaactt tttaacgaat aaaggagatt
     8401 tttcatgaca tcacttaaaa ctttactttt tggaacaact ttggctgccg gcgctgcatt
     8461 cttcatggga acgactgctc atgcggacga agcttatacc gttcaatcag gtgatactct
     8521 atcaacgatt tctcaaaaat acgttggtga taactccttg atcaatgcca ttgcagaatc
     8581 aaattcaatt tctgatatta acctgatcta ctcaggacaa caattaacaa tcccaacaga
     8641 aggctctgca caagcagctg ctgaacctca agcagccgtt caagaagcac cagtccaagc
     8701 tgaacctgtt caagctgaac aacctgttgt acaagaaacg gttcaaacgg aaacacaagc
     8761 agcgcctgtt gctgaaacac aacctgctcc tgctgtaaca gaaactgctg ctactccagc
     8821 aagtacaagc tctgcaaaag aatggatcgc acaaaaagaa tcaagcggtt cttacacagc
     8881 aacgaacgga cgttacatcg gccgttacca attagattct tcttacttaa atggtgacta
     8941 ctctgctgca aaccaagaaa gagtagcaga acaatatgtt acttcacgtt atggttcttg
     9001 ggaagcggcg aaagcattct gggaagcaaa cggttggtac taagattcat tatttgaacg
     9061 tttaaacaca ttcaaaatat agtaagaggt catgcgattt attctttcgc atgacctctt
     9121 tttgagttta agtttagtct ttattcctta actatcgttt gccagtattt cttgtatcag
     9181 aatctataaa tctactattt gaatcaatct attaggtttt aaactgtccc accttcacac
     9241 aaattttttt tgatttattt gaatctggtt ccgttgttta aaatttttcc tatattcttt
     9301 tagataatat gttattttct ttctcatcgc tccaggtgta ccttctcttt ataaaaaaac
     9361 aaattatgcg gctaagaaga ctcgaacttc cacgaggtca ccctcactag cgcctgaagc
     9421 tagcgcgtct gccaattccg ccatagccgc atcacatctt ttagtttagg attacatgtg
     9481 ttttttgtca agaacatatt tttgttcttt ttcatttctg tacgccctcc cttatgccat
     9541 ctacacaaat aattcatccg agcaactcca tcatctattg agggttggtg aaaaaatctg
     9601 ttttatccat atgatcgatt tcaatgttaa acgaacgact ctgggattag taactatttt
     9661 atttttttct tcatttcttt tttcctcttt ttctcgattc agctatcttc tttcatttgg
     9721 atattgatta tttcttctgt tgattactat ccttctggaa ttctagacgc tgaagtaatt
     9781 cacgttttct ttcttctaga gatcataagt aacgaatgaa cgaacttcaa ataatttttt
     9841 tattgtaatt catatttgta ttgttcgatg attcttaata cgatatgaca caataaataa
     9901 aaataggcat ggctatttac aacaatagtg ctatagtaga aaacaaatga ataaggttac
     9961 ttaaagaggt gaatacgatg aaactgatca aactatggga agcagattta aagaaagctt
    10021 atcagctaca aactagcttt ggaccaaatg agagtggatt tatcaacaat gcttatggct
    10081 atacatttgc tgaattttta gattatgtaa aaaaatgcga aaaaacgtct ttaggaatcg
    10141 atcttcctga gagttacgtt cccgcaaccg tctttatttt agaaagtgat gaacatgagt
    10201 atgtaggaat ttttaatttg cgccataaac tgaacgaaac attaagaaac ggcgctggcc
    10261 atattggtta cggcatctcc cctaattatc gtaaaaaagg atatgccaca caaggattag
    10321 cattagtact acaagaggca aaaaaaatcg gcattgatga ggcacttttg tctgtaaata
    10381 aaaaaaatct tggcagtctt aaagcacaac aaaaaaatgg ggctgcgatt tatcgtgaag
    10441 atgagaaaga atactatacg aaaatcaaac tgatgtaaaa aagaaggatt ccaaaaggaa
    10501 agggatttga atgtccttta tcaatagaac acatttattt aattaactta taatatagca
    10561 gacaaaattt tataaacaaa gaaacctttt atctcttttc ttctagaaag gataaaaggc
    10621 ttttttgttt ttcctatttg cttctcatag ctagtcagcc aagatttcta tcgtatcccc
    10681 aacgcaatcc gtgcataacg gctcatctta tctgtcgtcc atgctggata ccagactagt
    10741 ttgacttctg ctttcgttac ttctggcact tcttttaatg cgtcatggat agattctgtt
    10801 aaaatatctg ctaatggaca gcccatagtt gttagagtca tcttaatgac tgtttctcca
    10861 ttttcaggat tgaattctat atcataaatc aagcctaaat tgacgatgtc gattcctaat
    10921 tcaggatcaa tcaccatttc caaggcagca agaatacgtt ctttgattag ttctatttct
    10981 tgtccagacc gttcttggtt tgcttcgctc atcgtacgac actccttaac acgattttta
    11041 tttatcatac tcttttttta gctgcttgta aatgagaatt tagaagtaag attctcgttt
    11101 aaatttataa aaatgttctt attagatgta atagattaaa tttattctaa aataaacctg
    11161 attcctcatt ttttttgtga acgatttttt atttctggca atacgccagt tgttcgatac
    11221 attttttgtt cgttttcatt tgcaaaccgg ccaaatactg aatgagttgg taaaatattg
    11281 ataaatgcat cgtcgtcgat ttcatgaacg atctgatcaa gatcatacat ttcgtagcgg
    11341 gtgatgacca tcatgatcat gttcccttgt ttttttgaat agccaccgac agacggcagt
    11401 aatgtcattc cacgtaccat ccgttttgct agttcttctg ttacctcttc tggcttgacg
    11461 gtaacgatca ttgctgttac tttttgatga ctcgtgtgga tggcatcaat tacttgagtc
    11521 attgcataaa tggaaataat cgtatacaag gcactttccc agttaaagaa gaagcctgcg
    11581 atgactacaa tgataccatt tagaatcagc atgtagtttc cgactgtttt tccagttgtt
    11641 tgtgaaagta caagagagat gatatccatc ccaccagttg taaagcccat ttttaaagat
    11701 aatcctacgc caagacctaa taaaacaccg cctactaggg cattcatcaa aatattatca
    11761 gtgatctgtc cgactggaag cagcatcgtc atcaccgata cacatacaac attcacaaaa
    11821 ctaaggatcg ttgctcgttt tcctactttg agaaacccta atacaaacac agggatattc
    11881 aaaagaaaaa taaatgttcc tgtgtctatc ttgatatgaa accattcata taaaagcgag
    11941 gaaatgattt gagcgatccc attcatccct gcagaaaaga cattggctgg aatcaaaaaa
    12001 taatttaaag cgaccgcagc ggtcaatccg gttatcaaaa taaccactat tttctttaat
    12061 ctttcatttt tatgatacgc agtcataatt ttactcacaa gcacctctcc cctactttgg
    12121 tattccaaat gtaagaataa cagtttatct attaaaataa aatacttcga actcaaatga
    12181 gaagaatttt agcaaacagg taagaatctg ccctaatcct atgataagat agatgtatgg
    12241 taaatattta tatgtatatc aggagggttc ctatggcaaa agatgctagc ttcgacattg
    12301 tatcagaagt caatacagaa gaagtaaaaa atgcgattca gcaaacaaca aaagaattgt
    12361 ccaatcgctt tgacttcaag gattctacag tagaaatcaa attagagaac agcaatctag
    12421 ttgtattgag cgatgatgat ttcaaaatcg aacagatcaa agatgtatta tttggtaagc
    12481 tgatcaaaag aaatgtgcca atcaaaaata tccatttttc cgaatcagaa cacgctctag
    12541 gtggcaaagc tcgacaaact gccgatttgg tcaacggaat cgatcgtgaa aacgcgaaga
    12601 aaatcactac agctatcaaa aatgaaaaac tgaaagtaaa agcacaaatc caagaagatc
    12661 agattagagt gacaggtaag aaccgtgatg atctacaagc tgtgattgct ttattacgta
    12721 aacttgactt accaatcgag ttgcaattca ctaactatcg ttaatcaaaa aacgaggctg
    12781 acgtctgtca ttcctcgttt ttttgattta ctgcttcttt tgataaccaa aaacgctgta
    12841 ttccttcttc caattcccca acacttcgta cttctcttgc tgtttgccaa tgttgtggga
    12901 ataaacgtcg ataagaaaaa ctagaaaatc gttgatctgc caatacaacg attccttgat
    12961 ccgccatgcc acgaatcact cgaccaccag cttgcaagac tttgttcatt ccaggaagct
    13021 gataagcgta agcaaatcca aggtgttcct tctcatcata atatgatttg atcagttcct
    13081 gctcatgatt catctgcggc aaacctacac ctacgatcat actgccgatc aatcggtccc
    13141 ctctcaaatc gattccttct gaaaaaatcc cgccaagtac gcaaaatcca atcaatgttt
    13201 cagcgggatt tgtttgaaat tttgttaaaa atcgttcgcg ttcttcctca ttcatgtccg
    13261 tttcttggat tagcacattg ctgtcgggat attgctgtct gaatgcttcc accgcaagat
    13321 ctaaatattg ataagaagga aagaaaacga aataattccc gacctttcca tcagcaaaag
    13381 catgaatcgt ctctactaat tttgccagac tgtgttccct ttttcgataa gtcgtctcta
    13441 ggtaatttgc gatgaaaact tgctggtttc cttctgggaa aggactcggc agtttgtaag
    13501 ccagactttt ttgtcccccc agtgtttcct gataataaga gagtggtgaa aaactagcag
    13561 aaaaaagaat actgcttttt cctttatcca acgactgctc aagaaacaag cttggatcaa
    13621 tacaaaactc ttttactatc agatcgcgat acgttttttc gactgttgtt tcgtagtgat
    13681 catcataaaa ttcactgacc ttcaaaaaat gaagcaaatc aaaataataa ggaagcaatt
    13741 gttcttgtga tgggtgctca ggaaattctg ccagccattc tttaattttt tcgcttaatt
    13801 gataacctgc ctttactaaa gattcagccg gtgctttttg atgatgataa tcccaatgat
    13861 cttcttttgc tatttctcgg atcgaatcaa attcttttaa tagtttgttg aaacggcgat
    13921 gaagtttttt gaattccttt ggtatagctt ccttacttcg tttcgttttt tcataagata
    13981 gttctgccga atacatctct cgggaacgat tcaccaaatt atgtgcttcg tcaatcaaaa
    14041 acagatagtc ctcgtttttt tcatcttcaa aaaaacgtct taaataaaca gttggatcaa
    14101 ataaataatt gtaatcccca atgattacgt cacaccagat actgacatct aatgatagtt
    14161 cgaaaggaca aagtgtatgc tttcttgcat aagtttcgat gacttcacga gtgatctgat
    14221 tctcatgatt caaaagatcc cataaacctt cattaatccg attgtaataa ccattggcat
    14281 atgggcactg atctggatta caggtcgtct catctaaaaa gcagatcttg tctttcgccg
    14341 tcaaagtgac actttttact tcagctcctg tatcttttaa tgctgtcata gcatcttcag
    14401 ctacttgtct agttattgtt ttagccgtta gataaaagat cttttctccc tcttcttccc
    14461 ctacagcttt caaagcgggg aataacgtag agattgtttt tcctgttccg gtaggtgctt
    14521 ctacaaacaa tttctgtttc gtacggatcg ttttataagc agctaccgct agttcacgct
    14581 gacctttcct atactcatca tgggggaatt tcaaagccat caaagaggca ttgcgtacag
    14641 tgcgccagtt ttcttgaaaa acaagccatt ctttataatc ttcagtcagc tttttaaaaa
    14701 aagtttctaa ctgctctctt gtctgatgtt caacctttct cgtgatcact tcttctgccg
    14761 tctggaagta agtcaattgc agatttattt cttgtaaatc atgttcttga ctatagatat
    14821 aggcatacac ccttgcttga tgaaagaaaa gttccacttg ttctggttct aaatcttcaa
    14881 atcgtggttc ggaggttttg atttcatcta tataataaat accgtctctt ttgaaaatac
    14941 cgtctgcacg gccttcaacg atcaggtaat attcatctaa ttgaactgtt gtttttaaaa
    15001 agacttcttt ttcatagttt tctcccgcat ctttttggag cttgcggtgg attctcgctc
    15061 cttctaatgc agtatggtta ctttttttac gattgtcgat acttccacgt cgcaaaataa
    15121 attctactaa gtgccgcaca gatatttttg actgtttgat catttccacc acctctttct
    15181 ctctaagatt acctgaaaaa acctagttta gcaaaaagag ctctctttcc aaacataaaa
    15241 aaacaccctg ctgattaggc agggatatag gatatagaat ttggattttt ggatgaatct
    15301 aatgtaacaa ggacatatta aaatgctatg aaaacttact ttccttctct ttagaatatc
    15361 caaatacttt tcatatagtc tgataattca gataagtaaa gagaaataag tacctgtttt
    15421 tgtttcctag caatgaatgc gttatactaa tggatgaaag aagttttggc tatcaaggag
    15481 gaatgcacat gcatatcgaa agattaaaaa caggaatgat tgaagaaaac tgttatttgg
    15541 tctacaacga agaagcactt ttgatcattg accctggaga agatgcggaa cgaatcaaac
    15601 aagaaatcaa aaaaacaaac caacagccgg tagcgatttt gcttacccat actcactacg
    15661 atcatatcgg tgcagtggaa cctttacgcg cgtattatca aatcccagtt tatgtcagcc
    15721 cactagagca aaaatggcta ggtgatccga ttttgaatct ttctggactc ggtagacatg
    15781 atgatattgc tgatgttatt gtctcgcctg cagaatatga atttgaaatg aaaacttata
    15841 ctttaggaaa catgtctttt cgcgtcgtcc ctaccccagg gcattctata ggaagcgtca
    15901 gctttatttt tgatgatttt gtcgtttctg gcgacgccct gtttagagga agtatcggta
    15961 gaaccgatct gtatacaggg aatttagaac aattacttca tagtattcgg acccagctgt
    16021 ttgtattacc tgatgaattt gcagtctatc caggacatgg cgatgcaacg acgattgaac
    16081 aggaaaaaag gacaaatcct tttttcaatc gttaaaacga cttaggagga gaataaaatg
    16141 acagaaacta cactttatat cgtacgacac ggaaaaacga tgttcaatac aattgaacga
    16201 gtacaaggct ggtgtgatac acccctcaca aagcaaggac aagaaggcat tcattattta
    16261 ggtcgcgggt taaaaaatgt cgacttttca tttgcttatt ctagtgacag tggtcgtgca
    16321 atcgaaactg cccgtattat tctaggagaa cattctaagg gaaaagaaat tccttatttt
    16381 attgaaaaaa ggattagaga atggtgtttc gggtctcttg aaggtggata tgacatggaa
    16441 atgtggggtg tgatccctcg tgtattgaat tttaaaacat atgatgaaat gtttaccaca
    16501 gaagtttctt ttgaacaaat tgctaatgct gtatacaact tagataccgc tgggtgggcg
    16561 gaaacttatg aaacattgcg agaccgtgta tggacaggat ttgaagatat cgcccatcac
    16621 tgcgaaaaaa atggtggtgg aaatgtttta gtcgtatctc atggtttgac gatcgccttt
    16681 ttgcttaatc tgatcgatcc taaacagcct gttcgtgctg ggcttttaaa tggcagcgta
    16741 acaaaggtca cttatgcaaa cggtcgattt tctatccacg gcatcaatga tacgtcttat
    16801 atcgataacg ggaaaacaca tagtcgcgac tcgtttctat aatggggata ttttaatttt
    16861 taccagagaa tcataaaagg caaagtctga acgagggctt tgtcttcttt tttctcttcg
    16921 tgtacttatc tgctttattt ctcaagtttt tcttaatatt aaaaaacaga ttgggtttct
    16981 caaaaaataa cggtatacta taagatgtat cttaattggg aaggaaggaa tttatgtttt
    17041 ttgcaaatat tatcaaagca gtgattctcg gtattattga aggaataacg gaatggctgc
    17101 ccatcagtag tactggtcat ttgatcctag cagatgaatt catcaaactg gatgccagtt
    17161 cacaatttat gtcgatgttc aatgtcgtta tccaattagg ggcgatcttg gctgtcgtcg
    17221 ttctttattt tcacaagtta aacccatttt ctccaagtaa atcaacggta gaaaaaaaag
    17281 atacgtggac actttggttt aaagtgatcg ttgcttgcat accagccatc atcattggtt
    17341 tgcctttgga tgattggtta gaagcaaatt tccacaagtt cttaccagtt gccattgttt
    17401 tgatcgttta cggtattgcc tttattattg tcgaaaaacg caacaaaaac aaaacacctc
    17461 gttggacttc tctgaatgac tttacgtacc aagcagctct tcttgttggg ttattccaag
    17521 tcttggcact tgttcccgga acatcccgtt ctggcgcaac gatcctagga tctatcttga
    17581 ttggtgcttc gcgttttgtc gctacagagt tttcattttt cttagggatt cctgtcatgt
    17641 ttggcgcaag cggcttgaag atcgtcaaat atttagctga agggaattca ttcaaaatgg
    17701 aagaaactgt tgttcttctt gtaggaacat tcgtatcttt tgtggtttcc gtcttagcta
    17761 tcaaattctt actaagctat ttgaagaaaa acgactttac cgcttttggc tggtatcgta
    17821 ttatccttgg tatcattttg attggttatt ggtttattgc aatgtagaaa aaaccagaac
    17881 acttctctta tttgagaaat gttctggttt tttattttct ttaataataa tcattataaa
    17941 taataaaaac aacatcaagc ttaatcacca aatgataacc attatcgttc tcatttagct
    18001 gttattatta tcaattacat ttttattatg ctatccttgt tttgacaagg aggtctaata
    18061 acgatgacta atcagaaaaa agcttttgca gcaacaatcg gctgcctttt atttatgatc
    18121 ttcggtttta tcttcgaccg attctctctt accatcaccc cactttttta tatcagtgcc
    18181 attatcatcg gtggatataa acaaacatcg gaaggcttga aagaattgtg gaatgatcgg
    18241 acactgaatg tggatttatt gatggcttta gctgctattg gtgcctgttt gatcggtaat
    18301 tactttgaag gagcaatgtt gacattcatc ttttgtttaa gcggtgcatt agaggaatac
    18361 acaactaata aaagtcaaaa agaaattact gctttgatga atcttcaacc acaaaaagcc
    18421 caattattaa aagaaaatgg acaaatgcaa gaagtagatg tttctcaact aaaggtggat
    18481 aacttggtat ttgtcgctaa aggagcagct gttccgatag atggcttttt agaaagcaca
    18541 caggcaacga tcgatgagtc tgcattaagc ggtgaatctg tgcctgtaga aaaatattta
    18601 ggcgatgaga tgtatgcagg aacgctgaat caaggaaatc ccatcacgat tcgagtaaca
    18661 aaaacgagtt ccgaaactgt ctttgctaag attatccaat tagtagaaga agcgcagaat
    18721 acgccaactc aaacagcttc atttatcgaa cgaatcgaaa ataattatgt aaaattgatt
    18781 ttgcttgctg ttcctctaat gatccttctc ccccactttt tcctaggttg gagttgggat
    18841 gaaagctttt atcgaggaat ggtattatta gttgtggctt ctccttgtgc gcttgtcgca
    18901 tctgctacac cagcttctct agctgctctt tcaaattctg caaaaaatgg gattttaatc
    18961 aaaggcggta tccatttaga aaagctttct gaattaaaag cgattgcctt tgataaaaca
    19021 ggaacgctca ctaaaggaaa accagttgta actgacagct ttttctttga tgaaaaggat
    19081 ttggcacaac aacttcttgt tgctatggaa caaaaaacga cgcatccact tgctcatgcg
    19141 attttgcaat atttcgattg cacaatacct gaagaaatcc aatacttacc aatagaagaa
    19201 attactggtt ttggattaca aactacctat ttaggtgcgc aatggaaagt tggcaagcac
    19261 gcatatgatc ctgagacgat gataatcagc aaagagattg cggaaatgat cgaacgtttg
    19321 gaaaatcaag gcaaaaccgt gatttatctt tctaaagatc agcagttaat tgctgtttta
    19381 ggtctgctag atattccaaa agcaaatacc caacaagtaa tttcctactt taaatcccaa
    19441 aacatccata caagtatgat aaccggcgac cattctggca cagcaaaggc cattgctgaa
    19501 caagtaggga ttgaacatta ctatgcaagc tgtactccgg aagaaaaaac acaactagtc
    19561 aaaaaagaga atgaacttta ccaagtaaat gcgatggttg gtgatggagt caatgatgcg
    19621 cctgctttag cagccgcttc tttaggtgtc gctatggggc aagggacaga tgccgctatg
    19681 gatatcgcag acatcgtctt aatgaaaagc gacttaaata aatttgtcta cagtcatcgg
    19741 ctatctttaa aaatgcggcg gatcatcaaa caaaatatta ttttttcgat tcttgttatt
    19801 ctcttgttga ttgcttctaa cttcctgcaa tttttaaatc tacctcttgg agttgtagga
    19861 cacgaaggaa gcacaatatt ggttattctg aatggcttgc gtttactaag acctttacct
    19921 gatctttctg attcttcaaa aaaatgtaag tcttgtccac tatacaaagc gcggctgtct
    19981 tctgtcaaat aagcaaagtg tttttttatg attttgttta ttttatgaaa aaaacagctt
    20041 atgaataggt cttgaaggat gaattcctac ttttgtaact ttctaaaaac atgttatgat
    20101 tgtttcgaag aaagtgagga atatatttca tggaaagttg gcttttttta ggaattattt
    20161 tacttgtagc aattttagct aaaaatcaaa gtctgatgat agcggcagct tttgttttga
    20221 ttatgaagct cataccagcc tcccgttcct ttttcccttg gcttcaaggc aaaggaatca
    20281 atattggggt gacgatcatc acagcggcta ttctaatccc tatcgcaaca ggagaaatcg
    20341 gtctacgtga tctattagaa gcctttaaat cccctattgg ctgggtagct gttttttgcg
    20401 gtgggctagt ggctgtctta tcttccaagg gtgtaggatt gattgcttct gatccacaaa
    20461 tcactgttgc acttgttttc ggcacgattt taggtgttgt cttcttaaga ggaatcgccg
    20521 ccggaccggt cattgcttct ggtatcactt actgtatctt acaagtattt gctttaggaa
    20581 aatagaacaa attttgtcta ttttaggaga ttcttaacac ccccaattta ctgatccgtg
    20641 atatactgac aacgaggtga tacaatgttc gaaaaattaa agtatttcat aggaacaatc
    20701 ggctggtttc ttctagcggt acttttgatt ctgggcttag cttatctatt atttcctgat
    20761 ttgatacaaa atgtgtttga tactgctttt tgattgacct attaaaacga tataggggat
    20821 gctcctgcga tgcaggggct ttttttaatc aatgttttgt aataatttag gccgtgccaa
    20881 tgagacttcc tatagaattc gatgctcttt tttctttttg gctcttctgc tcttttttgt
    20941 tatactagat tacagtggac aaaagaaaga atgatcgcat ccacttcaac gaatatcaaa
    21001 atggaagaat tagtgcctgt tttcaggtta ctttgaaaag aaaggaagac gcttgtggaa
    21061 acttttgaag gtcttttaat tgatacgtac gttttacaag aacagccaat gatgctgact
    21121 gggatcaact tgcagcttga ggaccgtgtg atcaatggcc tgcttaaaga tcgctatttg
    21181 gcaaaatata tcttacgttt gcccctaaat aaatatgtgc tggaagtaag tggcaaatgg
    21241 aaccgtcgga accagttggt cataaaaaaa atgttgataa aaaatatcga tgaatacatt
    21301 aaaataatcg gtacaccaga atagccttta ctgatcaaag gatactggtt ataaaataac
    21361 tgcagtttct taatagaaaa acaaagaaca acagggaatc gtatcccttt tcaaaaaaaa
    21421 ctttgcaaac ggttctcttt gttatataat aacttagtac caaacattcc cattcaaact
    21481 ttgtttaaat agataaataa aaatctagtt tggtttgacg ctattgcctc ccacaatagc
    21541 gtctttttga tttttttcag cttgtactat ccgtttttac tgaaaaaaaa tcctaataaa
    21601 agactgttaa ggaaaaaaac ttgtcatgtt catattgcaa agcacgctgc ctttaggtat
    21661 aataatgaat gttgaattat gcggtaacac gcgtaagaac ttaagttatc ggaggtgaaa
    21721 ctaatgccaa acattgaatc tgcaatcaaa cgtgttcgta caagcgaaaa cgctaatgtg
    21781 aaaaattcat ctcaaacaag cgctatgcgt actgcaatca aaaaatttga agatgctgta
    21841 gcttcaggtg ctgacaacgt agatgcgtta tataaagaag ctgttaaagc tattgatatg
    21901 gctgaatcaa aaggtctaat ccacaaaaac aaagctaacc gcgacaaatc tcgtttaagc
    21961 aaaaaaatcg ctaaataaaa gaatcggctt cggccgattt ttttatttgt caaaaaaagg
    22021 acaaaaacaa acgaccttcc cgcatgcttt gccctcgtct ttcttcttat cgatttctta
    22081 acaactgccc tgtgcgcaaa acgaatagtt gaaaacttaa ttctttttcg atttgtcccg
    22141 ttttgatttg ataatccatc tcaactaatt gatcaaacaa ctgtaccagc aaatgttcat
    22201 cgaatttttt tacttcctgc atggcaagtt ttacacgata tggatggatt ttcaatgttt
    22261 cagcaatatt tgcctgctga taaccaatct ttacaagaaa ttttgtctgt aaaaataaac
    22321 gtaattgaga aagcaaaatc gcattaattt tgattgtttc ttccccttgc ataactaaat
    22381 cttcgtataa acgcaaagct tgttccgtct tcccttttaa aatatattgg gtcatgtcaa
    22441 aaatattatg ttctaacgtt ttaggaacta attcttctac ttctcttacc gtgatttgct
    22501 gttgattttg tccataaagg accaatttct gtaactctct catcattttg gataaatcta
    22561 agtcggtcaa cctcaagaat aaatcaattg cacttcgttc cattttgatt gaggaattct
    22621 ctaaggtatt catcagatat tgacgtactt ctttttcatt caactgttgg acattgatga
    22681 taattgctgt ttttttcaat tgtttcgtta cttttttccg ttcatccaac ttttcatatg
    22741 gcgcaaagaa tactaataca gtcgattcta atggttcttt caaataagcc gtcaataaat
    22801 cagtattttg ttcgattcca ttgtttactt tttcacctgt taaaaaataa ggattctcta
    22861 cgaatactaa ccgttgatct ccgaaaaacg gcaacgtctc tgcttcagct actacctcat
    22921 ctaaacttgc attttccatg tcaaaactta aaaaatttaa gtcatcttcg ccctctaatt
    22981 ggattttttt gacaatttct gtccgaactt gatcttggag aaacttttct gttcctaaaa
    23041 tcaagtaaca agatgcaagt ttttctttac gtattttttg taactctgct tgtatactca
    23101 aattactcac cactttcaaa aattatccta ccatgagcag atgagaatta ctagtctatc
    23161 attgtttcca ctagcccatg aggatgaaaa actggatgcc agcgataggt gatcattcct
    23221 tgttgatccg ttcgccatgt ttttatctga ttttcttcta gtgtctccaa tacttcgctg
    23281 tgcgggtgac cataacgatt atttacgccg caggatataa tcccatgttt tgcttcaata
    23341 tgggaaagaa aatctgtgtt acttgacgta cggctaccgt gatgacctaa tttgactaca
    23401 tcggctttca gattaggata aatcaaaagc aattgttttt ccattgcttg attcaaatct
    23461 cctaaaaata aaaagcgcct attgttatat tccatccata gaccaatcga atcttcattt
    23521 cttccctctc ccttttcaaa aggagtcaat acataaagat cataataacc gctgatcctg
    23581 tccccatgtt tgatttcaat gatctcagta ccattttttt gagcttcaga taaatgcctt
    23641 tgtaatggct catttcgtcc agcgccccaa ccgatataaa tttttttgat agtaaaatgc
    23701 tgagataacg tgggtaattc tcccacatga tccgtatcgt cgtgtgtcaa gatgagttta
    23761 tcgattacac ttatcccctg accttttaga tatggaacga tatttctttc agcaggagga
    23821 cgtatcatac cttgcgccca cttttctctt tcaaagtgta actgacctcc agtatcgatc
    23881 aaaatcgttt cttttcgaaa aggactttgc aaaaagatac tgtctccttg accgacatcg
    23941 ataaaagcga tcgttgaaga aaagcgtaaa aatggcaaag tcaaaaaaat aaaagaaaaa
    24001 agaccaacat aaaacaagtg tttcacaggt tgttctttca acctatccat acaaatcagt
    24061 aatccgaaaa tatacatccc agatagcaca aggggcaaac gtcctataat gagagacgac
    24121 cctgaagaaa aatcgattat tcgctcaaat aagattaatc cctcttctat cagcaaaagt
    24181 aaagtttccg gcagccagcg attgaagagt gtgagaaata acacaccagg aagaaaaaga
    24241 aacttgaata ccggtgcaat cagtaatgta aaaagactac ctaaaatagg ccactcataa
    24301 aaatgccata caatcaacgg catcgtgatc atagtaaaca ggacgtgaga ggccgttttt
    24361 ttcaaccaat ctccatcaaa agaaatcagg ataaacaaaa aactcatgaa aaaactaagc
    24421 tgtccacccg catgaaaaag aaatcgagga tcaaatagta aaagaagcca aaagacaact
    24481 gcaaataagt ccatggtgga ataatgctta ttcagcaatt tgactagcaa tcgcaataaa
    24541 aacagcaaac tagcacgcaa aacagaaata gaacttcctg caatagaaac ataacagata
    24601 gttagtagac tcaacggaat aatactgacg tgtagtggcc atccgatacg tcgaaataaa
    24661 taatacagcc accctaaata aaattggatg tgtagacccg atagactgaa cagatgcagc
    24721 aaaccactct ccctaaaaat ttcttctggt tctctgaatc ctgcatcttt atagccccat
    24781 aataaagaat taatatatac acttgttttt tgcggaaatt cagattggac aaaggagata
    24841 aaagatcctc tttttctctg aagccagttt cgccagtgat tttgcatggt gatctgttca
    24901 atcttttgaa tttggaaccg tccagaaatt ctatggttcc tgaagtaagc ttcttggtca
    24961 aaattataaa gattccgctt ttttgctgga gagatgaact cgccttcagc agtcaattct
    25021 attccctttc ctcggaagtt aagccatgtt ttcaattctg cttctgtgtt tacttgataa
    25081 gaaagctgga gcttttgttt attctctgat aaccttcctt ccattgtcaa aaaattacca
    25141 tttgcacgaa tcgtatctgt aaatacagta atttgcgcag atgttgtttt ttcctctaaa
    25201 aatgaatact cttgtagcct ataagaaatg gataccgtta tgctacacaa aatacacaag
    25261 tacgcgataa aacgtccttc ttttagcgaa aaccataaaa aaattccggc aagaagcaaa
    25321 cgataacccc aattgtcagt gtaatacaac aaacagataa tcatcgacgt aattgccgga
    25381 aaaatcaacc gatttcgaac atgcctttct aaaacgctag acatgttttc ctgttaattc
    25441 attttgaagt tttgaaaaat gctgtgagtc taaagcaact tggtgtacag atacacctaa
    25501 ttgttcgatc aacgcttggg cataaggatc atttcgatag tcatggagat aattgatccc
    25561 tttcacacca gcttgcaaca aagcctttgt acaggccaaa catggaaaat gtgtgacata
    25621 gatttctgaa ccttccgtcg ggataccaag ttttgcacac tgtaggagtg cattcatctc
    25681 tgcatggatc gttcgcaagc agtgtccatc cacgacgtaa cacccttcat ctatgcagtg
    25741 gacatctcca ctgactgctc cattatagcc gccagcaatg atcctttttt ctcgaacgag
    25801 tgtcgctcct acttctaaac gtgtacacgt actacgtaaa gataacagta ctgcctgagc
    25861 cataaagtac tggtcccaag gaatgcgttc attatgtgac ttatcagtaa ctttttcttt
    25921 attcgtatcg catgcttttg aagatttttc taacatgttt tatattcctc cgttttttca
    25981 agttgattaa aaagtactca ttgcttaaac aaaatattct ttaaatataa cgaatcatcc
    26041 tgtctgacaa aagatcctac ccttcactgc cgaaatgaag tccgtcatcc attagcccat
    26101 tataaaaatt cttcgaatcc atttgttcaa gaaattccgt ataaaaatcg atacttcaca
    26161 atcatggcgt tttgctactt ctgtgagaac agagatatat tctttgatca acttgttatt
    26221 ccgatatttt tgttttgtct catcgactgc tggtggcgtg ataaagaaag catgatcaga
    26281 actatagtct tttttcagct gaactatcat ccactgcaga ttttttggta cgtttcttta
    26341 gaaagttgtt tatgctctgc tagatcattc gtcccaatga gaataaatac tttatctgct
    26401 gtatagctaa gtacatcttt ggcaaagcgt tctcgtagag cttgactgtt attgccgctg
    26461 acagccgtat tcataatatg aatcccagat attttatttt ggagatagac attcagcatt
    26521 ggttttttta atgtttcttt gcgaacaatc aagctatttc ctatccaaaa atactacctc
    26581 ctcgtcctgc caagctctta gaattggatt attcttagta tccattagcg tccatttatt
    26641 gctcgtgcca gtcgattttg aatcattcta tttaattgta acgaagtttt ttagtttttc
    26701 aactgtcttt tcaccgatac cagaaatctc ctgcaggtct tccactttct ggaaggatcc
    26761 gttttcttct ctaaatcgaa tgatttcttg cgctttgact gatccgatcc caggaatctg
    26821 ctgaagttct gatggagtgg ctgtattgat atttattttg ggaggctcgg aatctgctgt
    26881 aggctgtttt ccttccgagg atgccaactg atcaagatgt tctggcagct cttcacctac
    26941 agcagggata tataggactt gctgatcttc tatcttcgca gaaaagttga ttcgatcgct
    27001 atccgcttct tctaataatc cacctgcacg ctttagtaca tcatagaccc gttcttctga
    27061 agaaaaggaa tagataccag gctccttcac acttcctttg atatcggtgt acatgacctt
    27121 tggacgagca tcctcttcta catcgtttcc ttcagctgat ggatcttctc cactggaact
    27181 aaacgaagaa agtatttctt ttgcagcagt ctcttctgtt tctctataaa atagcaaatt
    27241 tgataataaa aaaccacttg cgatacaaaa gataagaact atcatagaca tccaaatgat
    27301 caatttgggt gaagctagta ttttcttgct gattttttct atcattgttc ttttttcaaa
    27361 gaatgaccag taaaaatcat tcattactcc tttcatttaa aattgaagaa acagtgagct
    27421 ctggcaaaat cgtcccttca acatctaatt acgtcaattt tttcttttgt ttttattttt
    27481 atcgtgaa
//
LOCUS       DBGZHO010000034        27248 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.034, whole genome shotgun sequence.
ACCESSION   DBGZHO010000034 DBGZHO010000000
VERSION     DBGZHO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.034"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..181
                     /locus_tag="ACN3HL_001645"
     CDS             <1..181
                     /locus_tag="ACN3HL_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8006515.1"
                     /translation="NLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMKRVSYGFKSFEN
                     MRIRIFLINQLIKVR"
     gene            complement(291..1787)
                     /gene="lysS"
                     /locus_tag="ACN3HL_001646"
     CDS             complement(291..1787)
                     /gene="lysS"
                     /locus_tag="ACN3HL_001646"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HHC8006516.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1898..2902)
                     /gene="dusB"
                     /locus_tag="ACN3HL_001647"
     CDS             complement(1898..2902)
                     /gene="dusB"
                     /locus_tag="ACN3HL_001647"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HHC8006517.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2903..3790)
                     /gene="hslO"
                     /locus_tag="ACN3HL_001648"
     CDS             complement(2903..3790)
                     /gene="hslO"
                     /locus_tag="ACN3HL_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HHC8006518.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4007..6118)
                     /gene="ftsH"
                     /locus_tag="ACN3HL_001649"
     CDS             complement(4007..6118)
                     /gene="ftsH"
                     /locus_tag="ACN3HL_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HHC8006519.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6208..6753)
                     /gene="hpt"
                     /locus_tag="ACN3HL_001650"
     CDS             complement(6208..6753)
                     /gene="hpt"
                     /locus_tag="ACN3HL_001650"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HHC8006520.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6753..8198)
                     /gene="tilS"
                     /locus_tag="ACN3HL_001651"
     CDS             complement(6753..8198)
                     /gene="tilS"
                     /locus_tag="ACN3HL_001651"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HHC8006521.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8318..8788)
                     /locus_tag="ACN3HL_001652"
     CDS             complement(8318..8788)
                     /locus_tag="ACN3HL_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HHC8006522.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8834..9259)
                     /locus_tag="ACN3HL_001653"
     CDS             complement(8834..9259)
                     /locus_tag="ACN3HL_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HHC8006523.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9326..9595)
                     /locus_tag="ACN3HL_001654"
     CDS             complement(9326..9595)
                     /locus_tag="ACN3HL_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HHC8006524.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9606..11201)
                     /locus_tag="ACN3HL_001655"
     CDS             complement(9606..11201)
                     /locus_tag="ACN3HL_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HHC8006525.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11216..14737)
                     /gene="mfd"
                     /locus_tag="ACN3HL_001656"
     CDS             complement(11216..14737)
                     /gene="mfd"
                     /locus_tag="ACN3HL_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HHC8006526.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14754..15314)
                     /gene="pth"
                     /locus_tag="ACN3HL_001657"
     CDS             complement(14754..15314)
                     /gene="pth"
                     /locus_tag="ACN3HL_001657"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HHC8006527.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15667..16641
                     /locus_tag="ACN3HL_001658"
     CDS             15667..16641
                     /locus_tag="ACN3HL_001658"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HHC8006528.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16811..18211
                     /locus_tag="ACN3HL_001659"
     CDS             16811..18211
                     /locus_tag="ACN3HL_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HHC8006529.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18289..19011)
                     /locus_tag="ACN3HL_001660"
     CDS             complement(18289..19011)
                     /locus_tag="ACN3HL_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006530.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19090..19596)
                     /locus_tag="ACN3HL_001661"
     CDS             complement(19090..19596)
                     /locus_tag="ACN3HL_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHC8006531.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19719..21518
                     /locus_tag="ACN3HL_001662"
     CDS             19719..21518
                     /locus_tag="ACN3HL_001662"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HHC8006532.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21586..23160)
                     /locus_tag="ACN3HL_001663"
     CDS             complement(21586..23160)
                     /locus_tag="ACN3HL_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HHC8006533.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23415..23924)
                     /gene="mreD"
                     /locus_tag="ACN3HL_001664"
     CDS             complement(23415..23924)
                     /gene="mreD"
                     /locus_tag="ACN3HL_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HHC8006534.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23928..24782)
                     /gene="mreC"
                     /locus_tag="ACN3HL_001665"
     CDS             complement(23928..24782)
                     /gene="mreC"
                     /locus_tag="ACN3HL_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HHC8006535.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24937..25575)
                     /locus_tag="ACN3HL_001666"
     CDS             complement(24937..25575)
                     /locus_tag="ACN3HL_001666"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HHC8006536.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25576..26226)
                     /gene="rpe"
                     /locus_tag="ACN3HL_001667"
     CDS             complement(25576..26226)
                     /gene="rpe"
                     /locus_tag="ACN3HL_001667"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHC8006537.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26239..27138)
                     /gene="rsgA"
                     /locus_tag="ACN3HL_001668"
     CDS             complement(26239..27138)
                     /gene="rsgA"
                     /locus_tag="ACN3HL_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HHC8006538.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
BASE COUNT         7529 a         5901 c         4969 g         8849 t
ORIGIN      
        1 aaaccttctg acctatgaag aaggcatcac caacgcgatg atctatcctt acaccaatgg
       61 aaaaatagaa gcgaagaata cccatataaa gacaatgaaa cgagtatcct acggatttaa
      121 atcatttgag aacatgagaa ttagaatctt tttgatcaat caattaatca aagtaagata
      181 acaaaaaatc tgagccagaa tgaggttcat tctgacccag atttgatttt gtacaaccca
      241 tcagtcctta ttgacaaaga gccggaattc cttagacagc ttttattcga ttatctcatt
      301 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      361 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      421 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      481 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      541 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      601 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      661 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      721 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
      781 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
      841 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
      901 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
      961 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1021 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1081 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1141 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1201 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1261 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1321 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1381 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1441 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1501 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagtttt cccttttcct
     1561 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1621 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1681 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1741 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     1801 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     1861 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     1921 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     1981 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2041 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2101 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttctcctg
     2161 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2221 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2281 catccccgtt ccccataaat gggatcgtca aatgtttttt cacttctttc aatacttccc
     2341 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2401 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2461 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2521 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2581 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2641 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2701 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     2761 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     2821 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     2881 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     2941 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3001 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3061 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3121 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3181 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3241 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3301 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3361 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3421 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3481 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3541 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3601 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3661 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3721 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     3781 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     3841 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     3901 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     3961 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4021 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4081 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4141 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4201 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4261 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4321 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4381 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4441 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4501 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4561 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4621 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4681 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4741 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     4801 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     4861 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     4921 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     4981 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5041 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5101 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5161 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5221 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5281 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5341 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5401 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5461 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5521 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5581 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5641 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5701 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     5761 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     5821 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     5881 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     5941 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6001 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6061 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6121 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6181 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6241 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6301 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6361 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6421 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6481 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6541 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6601 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6661 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6721 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     6781 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     6841 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     6901 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     6961 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7021 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7081 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7141 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7201 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7261 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7321 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7381 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7441 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7501 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7561 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7621 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7681 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7741 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     7801 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     7861 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     7921 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     7981 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8041 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8101 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8161 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8221 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8281 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8341 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8401 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8461 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8521 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8581 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8641 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8701 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     8761 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     8821 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     8881 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     8941 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9001 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9061 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9121 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9181 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9241 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9301 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9361 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9421 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9481 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9541 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9601 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9661 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9721 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
     9781 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
     9841 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
     9901 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
     9961 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10021 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10081 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10141 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10201 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10261 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10321 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10381 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10441 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10501 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10561 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10621 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10681 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10741 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    10801 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    10861 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    10921 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    10981 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11041 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11101 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11161 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11221 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11281 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11341 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11401 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11461 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11521 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11581 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11641 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11701 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    11761 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    11821 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    11881 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    11941 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12001 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12061 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12121 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12181 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12241 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12301 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12361 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12421 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12481 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12541 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12601 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12661 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12721 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    12781 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    12841 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    12901 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    12961 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13021 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13081 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13141 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13201 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13261 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13321 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13381 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13441 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13501 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13561 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13621 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13681 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13741 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    13801 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    13861 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    13921 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    13981 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14041 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14101 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14161 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14221 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14281 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14341 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14401 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14461 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14521 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14581 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14641 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14701 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    14761 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    14821 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    14881 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    14941 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15001 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15061 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15121 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15181 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15241 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15301 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15361 gctaattagc ggtccagtcc atcgagcttt tttctttttt atacttgtca atgcatagta
    15421 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15481 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15541 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15601 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15661 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15721 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    15781 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    15841 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    15901 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    15961 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16021 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16081 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16141 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16201 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16261 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16321 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16381 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16441 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16501 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16561 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16621 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16681 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16741 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    16801 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    16861 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    16921 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    16981 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17041 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17101 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17161 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17221 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17281 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17341 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17401 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17461 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17521 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17581 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17641 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17701 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    17761 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    17821 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    17881 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    17941 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18001 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18061 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18121 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18181 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18241 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18301 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18361 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18421 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18481 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18541 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18601 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18661 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18721 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    18781 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    18841 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    18901 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    18961 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19021 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19081 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19141 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19201 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19261 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19321 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19381 cagatggtcg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19441 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19501 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19561 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19621 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19681 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19741 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    19801 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    19861 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    19921 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    19981 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20041 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20101 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20161 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20221 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20281 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20341 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20401 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20461 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20521 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20581 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20641 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20701 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    20761 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    20821 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    20881 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    20941 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga actgatcgta gccgatgcta
    21001 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21061 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21121 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21181 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21241 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21301 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21361 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21421 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21481 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21541 aaagagttag tccagaatgg gctaactctt tttgattaat cattcttaca tgctgacagc
    21601 aaagtcaggg gcaaaccatt gaactgaacc aacttttacg ctttcgcctg gttgaggagc
    21661 atggatatat tgtcctccgc ctaaagcaat cgctacgtgg taagttccgc cttgtgaccc
    21721 ccagaataac aagtctccag cttttgcttg agaaactgaa atttttgttc cagctgattc
    21781 ttgaggaact gtccaaccac cgatgtcacg accagttact tgcatgtaaa catagcgtgt
    21841 gaaccctgag cagtcaaagc cacttggatc tttaccgccc caaacatatg gagtaccaat
    21901 atatttgtaa gcttctgcta cgattgctgc accattcaca cttccagaag gagctggagc
    21961 aggtgttaca ggttttggtt gttcaggtgt tggtgttggc gttggagccg gagtactact
    22021 tcctgtgccg tttcctgtat caacactttg atctgttgat ggtgttgtag gcgcaggtgt
    22081 tgttgattct tctgttgttg aagattcagg cactgttgtt gattcttctg ttgctgaaga
    22141 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcgctgttg ttgattcttc
    22201 tgttgctgaa gattcaggcg ctgttgattc ttctgttgaa gattcaggtg ttgttgattc
    22261 ttctgttgct gaagattgtg tagctgatga tgattcttca gtcattgaag attgtgtagc
    22321 tgatgattct tctgttgctg agctttgtgc agtagatgaa gcttgagtag cttgtgcttc
    22381 agcctctgct tgttcgcgtg cttctttttc agctttttct tgtgcagctt gttgacgagc
    22441 ttgttctgct agacgttgtt gttcacgaat acgagcttgc tctgcttcag cttctgcttt
    22501 ttgacggttc aagtcagctt tcttgtcttc agcagttgct tgttcagcag ctaatgaagt
    22561 tttcagtacg ttcaaatcag cttgtttaga taaaagatcg cctttttgag attccaaagc
    22621 agcttggttt tcagctaatt cttttagttt agcatcgttt tcagcttttt tgtcttctac
    22681 agctttttta tcttgttttt gttgttccat caagtcgttg tttgctttta ccatcgttgt
    22741 cattgcttga acgcgtccaa tagcatctgc taatgaatca gcattcaata cagcatcgat
    22801 gtagtttgag cttgtgttgc ttacttgtgc ttcgcgtgct tgtttttgga ttgtatcttc
    22861 acgtttttca atacgttctt gtaaatctgc aatgtctttt actaattgtg cagattcttg
    22921 acgcaatgta tcttgttttg ctaataggtc ttgtgcttgt gtgttgattt cagaaacttg
    22981 gctttctaag gcatcgattt gtgattgtgc atctgcttgt tgatttttca agtctgcaat
    23041 cttttgatct tgctgttgta tctgagaatc aaaatcgtcc gccgcggcag cgatcggtga
    23101 tgctacggca gtcaaggtca ttgaacatac cattactgct gatattaaac tctttttcac
    23161 tcttcattcc tccgactggc ttaatttaat aaatatctaa atatatttaa gtctttctta
    23221 acgatataaa aattgtacca tagcagtgtg tcaacgatat aatagttatg ttacaaaaat
    23281 gtttcaaaac aacttttaaa aatgacaaaa ctgttcgttt cagaaaatga tcatgaaaaa
    23341 gccgcgttaa gtctagcatt tcttaagata acaacgattc tttttcgctt tcgacctaaa
    23401 aataaaaaaa gaaattattc atcactgaat aatttcttaa agggaaaaat gaataataca
    23461 aatataatca tgttcaacag cagtgtaggt cctaaaaacc ttgtaataaa atacgtgtta
    23521 tttactactg ctaatttaaa aatcaactgg accaccatcg taaacaattc ataacccgtg
    23581 acaaagatga tcatactgaa aaattcagta aagatgttga catggataac gtctttcatt
    23641 acatacatca accatacaat taaagggaga gctactgcat agataccgat aacgccaata
    23701 tagtaagcgt catagatagc cccgagaaca atcgtggtaa tcagtaaata acgtttttca
    23761 aacgccatac tgcaacataa taatgccaat atcagaaagt gggcatttga catataggtg
    23821 cctttcgacc actcccctag cattcttgtt aaatgaccat ctatcaacat caaaaagaac
    23881 aaaacgattg gcagatagta cttcattgtt tctttcttca acatggacta atcctccgct
    23941 agccgttgga caatcgtcac aactgacacg tcatacattt ctgcataagg tttcacataa
    24001 acttcccgat ccagcccata actatctggt ttcgttttaa taaccgtacc gatcggcaag
    24061 ttagctggag aattccctcc aagaccggat gtctggacaa catccccttc tttgatatcc
    24121 gtatcaccag ttaattgggt caccactaag gcatggagct tttcatcata gtttttaagc
    24181 aaaccaaacg cttcgccatt agccgaagat acccgtactg gaaaatgatt ggagctttca
    24241 ttagaggatg acagtaattc gattttagac gaagccgtat tgacctcgat cactcggcca
    24301 atcaatcctt tttgcgacat gactgccata tttgcttcga taccgtcttt agaacccttg
    24361 tctacgatca gcatgtcctg ccaactgtca ggcgaacgag taatgacatt tgccgttact
    24421 ttttcgtaac tagtcagcgt ctgattcaac tcaagttctt ttttcaacgc ttcgatttct
    24481 ctctcgtaat tcttgttttg ctgtgaaacg tcatcatagc tatcgatttt ttcttttagc
    24541 cgctcatttt cggcataagt tgaaaaaaga ttatggacag aatctactcc atttcgtacc
    24601 caccgtactg gggcagagat tgttttatca accattgcaa cactgtcatt aacgatggat
    24661 tggaagaaat tgggctttcc ttcattcgct cgctgcgcag cggtcacact tagtatcgtc
    24721 accacgatga taacaataac caaggtaata ataatatttt tattaggatt gaacttcttc
    24781 acaaagacac ctcgaattaa ttagactctt gtgttcaatt ttatcactaa atgccgtgaa
    24841 acaaaaggta agttgctcct cttaagcttt tttttagcaa ataatagatt ctgtcatttt
    24901 tagcctgaaa gacaaatttt tttatttgtt tatggatcaa tctttgcttt gaataactgc
    24961 aatcatacca tctgaaaaag aaaattctgc ggtatctgaa agaaattcgt tacttgcata
    25021 agatgtcgga tattctactt ctttattttc caatacatac ttgctgcctt ttaatgtaag
    25081 attcgagacg ggagtcaagc agcaataagc taaatacttc atatctggta tctgtcttac
    25141 tatatgctct ccaggcaaat aataagacaa ataattttga caatctctga taataagctg
    25201 atgggcaaag ggtttgaagc gaggttccat acctaaccag agattggcta aaagatgatc
    25261 caatcttccg cccgtagctc caatcaaagt gacttccgct tgcgggtaac gttcaaatgt
    25321 ttttaagata cctaactgtg tatctgtatc gtctttttct gcaggggaac gggtatactc
    25381 tttggctttt gcaaatactt ccttctgctc ttcgttcgac aatgaatcaa aatcgcccac
    25441 tgccagatct actgggtagc ctgcttgaag caggtacagc gcaccacggt ctatcccgac
    25501 ataggcatcg tatttggaca gcagagactg cggccagttt tgcggattac ctccagcagc
    25561 taataaaatt ttcatttagt ctaatgcctc ttttaatcgt tcgatttgtc cgactggatt
    25621 ttcggctcca tagatatatg atcctgcaac gaagacatcc gcccctgcat ctttacagat
    25681 ttttgctgtt tctggaacga ttccgccatc tacttcgatt gcataagtcc aattgttctc
    25741 tctacgtaga tcagcgagtt ccgtaatttt ttctactgtt tcttcaataa agctttgtcc
    25801 gccgaaccca ggattgacag tcatgactag tacttgatca gccaaaggca aaacatgttt
    25861 gatcatggag actggtgttc ctggattgat aactactcca gctttaactc ctaagctttt
    25921 tgtcatttga agtgcccgat gaatatgagg agttgcttcg acgtggacag taatgatatc
    25981 tgctccagct tttgcaaatg ctggaatgta gttttctgga tcaacgatca tcagatggac
    26041 gtctaacggt aatttagtaa caggacggat tgcctgaaca atatttggcc ctaatgtgat
    26101 atttgggaca aattggccat ccattacatc tacgtggatg taatctgcgc ctcctttttc
    26161 cactaactca atgtctcttt gtaaattggc aaaatctgca ctcaaaatgg atggtgctat
    26221 cttcattctt gtttcctcct attttcgttt accttctttt tttgcataca ttggttttct
    26281 tttttcgatt tcttgtaaga attgcaaata attgtcgtaa cgtgtctgtg cgataccacc
    26341 tgtttctact ctatgtttta cttcgcagcc aggttcttta gcatgcatgc actctctaaa
    26401 tttgcaatgg acagaagctt ctacaaattc aggaaattgt ctcggcagtt ctcctgcttc
    26461 aattgtcaaa aagtcaatcg agctaaatcc tggtgtatct gctactaacc cgccatagat
    26521 aggaatcagt tccacatgac gtgttgtatg ccgtcctctt ccaagtgcat cagaaatctc
    26581 tcctgttgct aaattcagtt ccggtgatat ttgattcagt agcgtcgatt ttcctgctcc
    26641 agactgaccc ataaagaccg atagccgttc tgggaagtaa cggatcagtt ctgtcgtatc
    26701 acccgtatga ttgggtacaa tcaccggata gcctatttta gtataggttt gcttgatctc
    26761 ttcgattttt tctgggtcgt ctgacaagtc ggtctttgtc aaaaaaataa tcggttcgat
    26821 cgactcgtat tccaaggtaa ctagaaagcg gtcaagtaga ttataagaaa atgcaggctc
    26881 tacgatactt gtgacaatga ttccaagatc aacatttgtg actggtgggc gaactaattg
    26941 attttttctc ggcaagattt ccagaagata gccgtctgtt tgattttcac tctcaaagat
    27001 cacctgatct ccgacaagcg gcgtgatttt ccgattccgg aaatttcctc ttcctcttgt
    27061 ttgataggtc tctccgtttg cgtatacata gtaaaaaccg ctgattgctt ttctgatttg
    27121 tcctttgata agtgccacct ccgtttttgt ttattttacc atacgaagag gaaagtaggt
    27181 gttattccat gcaaacttct caaagtatat ggcttgaaaa ttgatcaaaa gagatagaaa
    27241 cacaaaaa
//
LOCUS       DBGZHO010000035        26000 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.035, whole genome shotgun sequence.
ACCESSION   DBGZHO010000035 DBGZHO010000000
VERSION     DBGZHO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.035"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            289..606
                     /locus_tag="ACN3HL_001669"
     CDS             289..606
                     /locus_tag="ACN3HL_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HHC8006539.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(697..1062)
                     /locus_tag="ACN3HL_001670"
     CDS             complement(697..1062)
                     /locus_tag="ACN3HL_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006540.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1270..1752
                     /locus_tag="ACN3HL_001671"
     CDS             1270..1752
                     /locus_tag="ACN3HL_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006541.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1949..2839
                     /locus_tag="ACN3HL_001672"
     CDS             1949..2839
                     /locus_tag="ACN3HL_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HHC8006542.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            3165..5639
                     /locus_tag="ACN3HL_001673"
     CDS             3165..5639
                     /locus_tag="ACN3HL_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHC8006543.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5742..7478)
                     /locus_tag="ACN3HL_001674"
     CDS             complement(5742..7478)
                     /locus_tag="ACN3HL_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006544.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7475..8179)
                     /locus_tag="ACN3HL_001675"
     CDS             complement(7475..8179)
                     /locus_tag="ACN3HL_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8006545.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            8310..8813
                     /locus_tag="ACN3HL_001676"
     CDS             8310..8813
                     /locus_tag="ACN3HL_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HHC8006546.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8773..9111
                     /locus_tag="ACN3HL_001677"
     CDS             8773..9111
                     /locus_tag="ACN3HL_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HHC8006547.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            9132..10550
                     /gene="ffh"
                     /locus_tag="ACN3HL_001678"
     CDS             9132..10550
                     /gene="ffh"
                     /locus_tag="ACN3HL_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HHC8006548.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10662..11240
                     /locus_tag="ACN3HL_001679"
     CDS             10662..11240
                     /locus_tag="ACN3HL_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HHC8006549.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            11244..11765
                     /locus_tag="ACN3HL_001680"
     CDS             11244..11765
                     /locus_tag="ACN3HL_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HHC8006550.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11844..12398)
                     /locus_tag="ACN3HL_001681"
     CDS             complement(11844..12398)
                     /locus_tag="ACN3HL_001681"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HHC8006551.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12651..12926
                     /gene="rpsP"
                     /locus_tag="ACN3HL_001682"
     CDS             12651..12926
                     /gene="rpsP"
                     /locus_tag="ACN3HL_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HHC8006552.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12938..13189
                     /locus_tag="ACN3HL_001683"
     CDS             12938..13189
                     /locus_tag="ACN3HL_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HHC8006553.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            13313..14104
                     /locus_tag="ACN3HL_001684"
     CDS             13313..14104
                     /locus_tag="ACN3HL_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006554.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            14274..14795
                     /gene="rimM"
                     /locus_tag="ACN3HL_001685"
     CDS             14274..14795
                     /gene="rimM"
                     /locus_tag="ACN3HL_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HHC8006555.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14785..15546
                     /gene="trmD"
                     /locus_tag="ACN3HL_001686"
     CDS             14785..15546
                     /gene="trmD"
                     /locus_tag="ACN3HL_001686"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HHC8006556.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15682..16029
                     /gene="rplS"
                     /locus_tag="ACN3HL_001687"
     CDS             15682..16029
                     /gene="rplS"
                     /locus_tag="ACN3HL_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HHC8006557.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            16339..16581
                     /locus_tag="ACN3HL_001688"
     CDS             16339..16581
                     /locus_tag="ACN3HL_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HHC8006558.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16669..16815)
                     /locus_tag="ACN3HL_001689"
                     /pseudo
     CDS             complement(16669..16815)
                     /locus_tag="ACN3HL_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            16872..17186
                     /locus_tag="ACN3HL_001690"
                     /pseudo
     CDS             16872..17186
                     /locus_tag="ACN3HL_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            17215..18474
                     /locus_tag="ACN3HL_001691"
     CDS             17215..18474
                     /locus_tag="ACN3HL_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006559.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            18527..19423
                     /locus_tag="ACN3HL_001692"
     CDS             18527..19423
                     /locus_tag="ACN3HL_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006560.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            19434..20303
                     /locus_tag="ACN3HL_001693"
     CDS             19434..20303
                     /locus_tag="ACN3HL_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006561.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            20313..20988
                     /locus_tag="ACN3HL_001694"
                     /pseudo
     CDS             20313..20988
                     /locus_tag="ACN3HL_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            21194..22858
                     /gene="alsS"
                     /locus_tag="ACN3HL_001695"
     CDS             21194..22858
                     /gene="alsS"
                     /locus_tag="ACN3HL_001695"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HHC8006562.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22871..23581
                     /gene="budA"
                     /locus_tag="ACN3HL_001696"
     CDS             22871..23581
                     /gene="budA"
                     /locus_tag="ACN3HL_001696"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HHC8006563.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23711..24208
                     /locus_tag="ACN3HL_001697"
     CDS             23711..24208
                     /locus_tag="ACN3HL_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HHC8006564.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            24393..24653
                     /locus_tag="ACN3HL_001698"
     CDS             24393..24653
                     /locus_tag="ACN3HL_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006565.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(25015..25254)
                     /locus_tag="ACN3HL_001699"
     CDS             complement(25015..25254)
                     /locus_tag="ACN3HL_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006566.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            25540..25854
                     /locus_tag="ACN3HL_001700"
     CDS             25540..25854
                     /locus_tag="ACN3HL_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006567.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8636 a         4373 c         5306 g         7685 t
ORIGIN      
        1 agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat
       61 aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat
      121 caacgaaagt atactttata tagtcataac gccgatggta actatgcact gtaacgataa
      181 tgctgctaaa atatcttttt acgaaaaaca tcacaaggaa aaacttaact atggtattat
      241 ctaaacataa ttttttcggt atttaatatt taattaggag gtaatatttt gcttttttat
      301 agtaatttta tcttaatagt agcgatatta ttacttctga atatatggat ttttgatagg
      361 agtagaaatg caagtatagg ttttagaact aaacgaagtc tgtcttctaa aaaaaattgg
      421 gtatactcac aaactatttt ttatggagga attgttttaa ttagtttact ttcttcaaca
      481 ctttattctt tgaatattat agatgtttcc acctcaaatt caatatctat tattggaatc
      541 attattgctg caattattac acaactgttt ttagtgtttg gagagaagaa aagaagtaaa
      601 aaatagaaaa actagtgata gttttggtga tataagaaaa acatatatgt ataaaaagaa
      661 gaaagtagct tctctttgta catatatggt ttgtttttat ggatgccgag cttttttata
      721 agataaggct accgcccata acgacccaag gatttgtgga actaagtaaa tacctgcaag
      781 aagcaagatc agctgggtcg gttttaaagg atgatagaag taacgccatt cagtaaaatt
      841 ggcgcaaaat aaataggaag tgacagtaga tataatattg gcaatgaata aagatataat
      901 acgcctgttc ctttgaaaat aatatccagc aaaaagagat aaaaatatca atgtgatgaa
      961 cccgcttacg gaatgataac gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa
     1021 agataaaagc aacggaaggt ttttccagca agtttttatc atctttcatc accacctaac
     1081 aagtgttatt attttgttag ttttattgta aattgaatcc tgcaataatc aattactttt
     1141 tcattatttc tagattaaat gaataaactc tcatgccatt atctctaaaa aaaaagtttt
     1201 tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa gtagtttggg
     1261 ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt ttggtttttt
     1321 cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc ggagatatta
     1381 ggcctgatcc aaggaagcgg attagtggtt tctaggaatt ttccagcttt gactgttttc
     1441 tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca ctacaattgg
     1501 cagctgcttt acttttcttg cttattagta tttacatcta tgttttcttt gctgcctcgc
     1561 ttgattatcg gccctaatgg tttgagcgag agtggattga aggattcagc ttattcctcc
     1621 atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt tattcttgca
     1681 acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt atctataaaa
     1741 aataactatt gatggtggat catcagtaaa aaagcatatg agctgcgtaa aatgcatgtt
     1801 tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca tgatttttac
     1861 ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac tgataaactt
     1921 tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc taggtatgat
     1981 gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct ctgccacaca
     2041 aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt
     2101 acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa attatcaaat
     2161 ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg gagcagttac
     2221 tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt caaaattagt
     2281 ggatcataaa gtagcagtgg tcgggatggc accaatcgtc aataaagata cagatgtcaa
     2341 agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta actggaagga
     2401 agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg
     2461 cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc aagaacaaga
     2521 ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca gctatttagc
     2581 tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag aaccaaaaga
     2641 agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt acacgaacgg
     2701 aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag aaatccaaga
     2761 aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag aacgtgatca
     2821 cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta ctattaagga
     2881 aaaatcaact atgtttcccc acatatacat ttttccttta attgtgaaaa atagttcctc
     2941 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttattcga
     3001 aaaaaagagc tacgacatag aactgtcgta gctttttttt tgctatatga caggaatgaa
     3061 aggtgtttgc aagcttaatg tgaggaacac tttccatatc tgttctatac tggataggag
     3121 aagtttggaa atatccagaa aacgaaatca atcgaggtag ccacatgaag aataaatgga
     3181 taaatcgaag taaaaaaaag aaagtaacac aaagatcatc agataaagtc atccgtcttt
     3241 ttccatcgta taaagaagga ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg
     3301 cagcaaataa ttcagtcgat cccacattca aaacaaatca gcaaatcgta ttggaaaaca
     3361 tatttacgta tttcaatttg atctttctta tcttagccat tttgctttgt ttagtagaat
     3421 cctataagaa cttgactttt ttaccagtta tcatagccaa tacaggaatc gccatttttc
     3481 aggaaattcg atccaaaaag atcttggacg aactaaatgt tttaaataca gcaaaagtca
     3541 atgtcatacg agacgggata gaacaaacaa tagatataga agaccttgta atagatgaca
     3601 ttgttatttt agagactgga catcaaattc cagcagatgc agaggtcgtg gaagggaaac
     3661 tgcaagttaa tgaggcttta ttgacaggcg aagcagatga aataaccaaa gaaataggcg
     3721 atccattaat gtccggcagt ttcattgttt ccggaaaagc ttacgcccga ttagacaaag
     3781 ttggagcaga ttcgtatatt tcccagctga cagtcaaagc caagacaatg ggagaaggag
     3841 aacagtcgga gatgattgct tctcttaatc aattgatcaa atggattggg atcatcatta
     3901 ttcctatcgg tatcctgctt ttttctcaaa gttacttttt taatggaaac acgatcaaag
     3961 aaagtgtcgt tgcaatggaa gcagcattga tcggtatgat acctgaagga ctgtacttgc
     4021 tgacgacgat tgcattagca ttaagtgcga ctaaactagc aaagcaaaga gttcttttac
     4081 acaatatgaa aagcattgag acattggcaa gggtaaatgt cctttgtgta gataaaacag
     4141 gaacgatcac agaaaataaa atgtctgttc aaaaagtgat cgtctctaaa aaacaagaaa
     4201 taatcagtca gtcagatcaa ttggaagcat gcattgctga ctatgcaaaa gcgatggcag
     4261 gagacaatgc aacaatggaa gctgttaaag catattttac aaaaaccact gatcaatcct
     4321 atcaccatgt tattcctttt tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca
     4381 aggtgtatgt tttaggagcg cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg
     4441 aagagtttgt ttctttcgct gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg
     4501 ggattcttga agaaccagta ttgacagaag cagtcacacc attaggctat attctgattg
     4561 ctaatcctat cagaaaagaa gcaagagcca catttgatta cttcaaaaaa cagcaagtag
     4621 ccatcaaagt gatttctgga gataatccgc tcaccgtatc caatgtagct gtccaagcag
     4681 ggatttcaca tgctgatcag tacgttgatg catctaaatt atcagaagaa gaatatgaag
     4741 cagctgtcga aaaatataca gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg
     4801 ttcaattgct aaagcgtcgt aacaatacag tagctatgac aggtgatggc gtgaatgata
     4861 ttctagccat gaaagaagca gactgcagta tagcgatggc ttccggaaat gaagccgcca
     4921 tgcaggcctc acaagtggtc ttacttgatt ctgacttttc acgcatgcca gaagttgttg
     4981 cagaaggacg gcgcgttgtg aacaatattg agcgatcagc cagcttgttt ttagtgaaga
     5041 atattttctc ctttttgctc tcactgtttt cagtgatctt tgctctgacc tatcctttag
     5101 aaccatcaca aatcacattg attagtttgt ttactatcgg acttccatct ttcttgcttg
     5161 ctctagaaga aaacaaaaag cgaatcagag ggaaattcat catgaatgtg atggaaaaag
     5221 ctgtgccagg tggactaaca gatatgatcg tagtcggtgc gttggtgatc tgcggggtga
     5281 ctttgaatct aaataaaaca gatgtttcta cagcatctac catgcttttg attgcagtag
     5341 ggttcctcgt tctctataaa atctgttcac cgctgaataa attcagaagt cagatcattc
     5401 ttttctgtgc tagcggtaac tttttttcgg tcatcttttt gcataagctg ttttcaatca
     5461 ccggtatctc agctgtatca cttttgctgt tgagcattct atttttctcg gcagattcga
     5521 tttttaggca tttgaccaca ttggtagaat atttgtttga acgtaaaaat gaaaaagagc
     5581 aaaagccgtt tagtcgcgta gttaaaaaat ttctatcgat atttaaacga gaaaattgac
     5641 gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc gtgtatcttt cgaagcagga
     5701 tgagtcatcc aactttaaaa cgcacgagca gttgctcttt tttacatttt cggaatggta
     5761 acggtgaaag tcgaacctgt tccaagatga ctgtctacag taatcgtacc atgaaggagt
     5821 tgcacgtagt cttttacaat cgctaaccct aatccggtcc cgcctgaatg ccggcttcgc
     5881 gccttgtcta cgcggtaaaa acgctcaaag atccgttcct gatcctcaat gtcgatacct
     5941 ataccaaagt cttggacaga aaacgataga tcatctgttg cctgatagcg gataataatc
     6001 tcgctgtcgc tttttgaata ttggacagca ttttcaatca gatttttgat aattggataa
     6061 aggatatctg ttttagtagt aaatggttcg ttctttccaa tcaatcgaat cgtcaaccgt
     6121 ttcttttcga tgattggctg ataattttga acgatttgct ggaaataagg ttctgtataa
     6181 attgtctgga tctcgtaaga attctcgcca tcttttgaca gctggatgat ttcccgaatc
     6241 agtttatcta accggatcgc atctttttgc atgatctcaa gaaaagaagt cagagtttgc
     6301 gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac caatcagtga agtcacagga
     6361 gtttttaatt cgtgagagac gttgccaacg aaatcctttt gtagcttttc taaacgtcgc
     6421 actttcgtta agtcatacgc cacccctaga atctgtccgg taccttctga attagtaaag
     6481 tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa gggtgatctc ctgatggatc
     6541 agcggatgct caggagtcac ttgatgaatc agctgaatga gttttggctc ttgaatgact
     6601 tctgtgtacc gctgttcagg ttgatagctt accacgttta aatgtagctg catctttgga
     6661 ttaagcagta gtaaacgaga atcagcatca tcaatcagga atacgccaat catcagttcg
     6721 ttcagtaacg tatataattg ctcttctgtg gtagtatacg cccgatacat cttactcatt
     6781 tgttcgctca acgcattgat cgtctgatac aattcttccc attgatcggg tgtttgcatg
     6841 attacttccg cctgattagg attttgcacc atttttttta gtacgggcag cacggttttc
     6901 aatggctggt ttttttgata gatcagataa tagatcattc ctgcaagaac aaggaagaaa
     6961 gacagaaaga agaaaaagac ccaacggcga aaactctcag ttctcggtaa aaaaccgctt
     7021 gtcggttctg cgatacgtaa aatggcttct aactggccac tttttttgac tggtaatgcg
     7081 acatataaaa gatccccatt caaagtagta cttttgcgca aagcgctacc taggttccca
     7141 ccattcaata cggctttgat ttcgggacgg gagtttcgct gttcattcaa tgtttcattg
     7201 tttgtgtcaa ataagatctt tccagtagca tccattaaag taatccgttc gttcgactga
     7261 tggacgaatt cttccaaagc agttttgttt tgcgctgctt ggaggttttc gacatctaat
     7321 tgccggatca gcagttgtgc tttttttgtc aggtagcttt cttgctgttc cacgatctgc
     7381 tgttgaaaat aatgggaaat caattgccag ccaccaaaaa acaaactaac taaaagaata
     7441 agaaagaaga gacgttcata aatttttttc catttcatcg tttgggttcc tgaaacttat
     7501 agccaaatcc tctaatagtc accaagtact ttgggtgttt tggatctcgc tcgatttttt
     7561 ctcgcaaatg actaacgtgt acatctacga ttcggctttg tcctgcgaag tcaaaattcc
     7621 aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc ttttcgtttc atgaaataaa
     7681 caagtaattc aaattctttc ggtgttagtt caatcagatg gtcgtctacg gtcacttgat
     7741 aattggtcaa atcagcagtg atttgtccaa tcgatagata ttcaggctca gcttcatctt
     7801 ttgattgctt acgaggttca attcgtctga atattgcttt catacgggct aatacttcgc
     7861 gaggactaaa tggtttggtc aaatagtcgt cagcacctat ttctaggcca atgatccgat
     7921 ccacttggtc atctttagcc gtcagcatca aaatcggtgt ttcatttttt tcttgacgca
     7981 gccgctgagt gatctccatg ccatccatcg ttggaagcat cacatctaaa atgatgaaat
     8041 caaatgattg ttctaatgct aattctaatc cttcgcctcc atctgtggca ctggttacct
     8101 tgtagccttc tttttccaaa ttgaacgtca agagcgttac aatagaaggt tcatcatcaa
     8161 caactagtat ttttttcatt caaatctcct ttaaataggt ttcattctgt ttatatttta
     8221 gcatagaatc agtacaaagg gctattttac aaaagaaata aatggtataa taggaaggca
     8281 ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat cagtgcatgt ttaggcggtc
     8341 tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga attgatggaa ctagttgaaa
     8401 ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg attaccaatt cctagagatc
     8461 ccgctgaaat cattggtgga aatggattcg atgtgtggaa agatcaagca aaagtatgga
     8521 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     8581 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     8641 cccattcgat ttatgacggg agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     8701 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     8761 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     8821 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     8881 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     8941 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac ttcatctttt ttctaattat
     9001 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     9061 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     9121 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     9181 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     9241 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     9301 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     9361 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     9421 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     9481 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     9541 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     9601 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     9661 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     9721 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     9781 agattttgct tgttgtcgat gccatgactg gtcaagatgc cgtcaacgta gctgatagct
     9841 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     9901 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     9961 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
    10021 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactatgac gagaaaaaag
    10081 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
    10141 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
    10201 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
    10261 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
    10321 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
    10381 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
    10441 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
    10501 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
    10561 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
    10621 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
    10681 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
    10741 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
    10801 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat attaaaaaag
    10861 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
    10921 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
    10981 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
    11041 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
    11101 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
    11161 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
    11221 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
    11281 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
    11341 agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
    11401 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
    11461 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
    11521 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
    11581 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
    11641 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
    11701 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
    11761 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
    11821 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
    11881 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
    11941 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
    12001 acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
    12061 gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct tgagcctaca
    12121 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
    12181 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
    12241 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
    12301 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    12361 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct ccttcaaact
    12421 atctataaca atcttacaaa aaataagtaa ctggagcaaa taaaaacact tactgacaaa
    12481 agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa tcttctattt
    12541 cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag ggtaaaaaaa
    12601 aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata atggcagtta
    12661 aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc gtcgtagctg
    12721 attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac aatcctttga
    12781 aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta tcaaaaggtg
    12841 cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg caaaaacacc
    12901 acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa gcgacttagt
    12961 cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag acgtcgtaga
    13021 gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg gccgtatcat
    13081 tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg ttcggatcaa
    13141 tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa taaacgtgct
    13201 gtactcgaat tttcgagtgc agcttttttg tttttttatt aattgaagaa atgattattt
    13261 ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg agtgaacagc caatgagaaa
    13321 gaaaatgtta tttattccat ttgctctatt gttaagcgct tgtagttcgg ttactcaaga
    13381 atcagacaat acacatctat caagcagtat atctgaaact gttaccagtc cagaaaaaag
    13441 tagtaccaaa acggctacca ccactgaaca aacaatggct acctcaaata atgagaaaaa
    13501 gactgcttta gaccagttga aagaacaaca gccaaatgtt cccatgcctc tagatgtacc
    13561 agtctcttca ggctatctca atatcgcagc gacacataca aagcaaggtt attctatttt
    13621 atattacaga acagatcgtc ccctcgggtt gaatgctgac gaattgaatc aagaaacgcc
    13681 tattgcaacc tatctatatc aatatgggtt tgcttctagt caagaaacaa tccaagtttt
    13741 gcagcccttt gagatcgaca caaatggtca gcaagtggac ttaggttctc gaatcacagg
    13801 gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg caagaaggaa actggcgtat
    13861 tcgaatccgt gggaataata tagaaggcca agatccctta ctattagcta aagaaatcgt
    13921 agcttatttg gaagaaaaca gtctaccagc acctgaacaa tttggtaaaa ttactgttga
    13981 tatgggtgat acgacgaatc gagccgtaga agtaagctgg caagaaccga aaaatgccta
    14041 tacgatcact catcaagatc ctatgtctgc gttgaagatg gcagtttcta tgaagaggtt
    14101 gtgaaatcag cgcgctgatc tgagcccatc atttaactcc aagtcacagg aagtaatcaa
    14161 aaatagcacg ccgcattttt gcataatttt ggcttaatac cttaaaagaa aactagaatt
    14221 gcctcttcac acatgctaaa ataaaacaga caaaaaagaa atggggatat aagttgactg
    14281 aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat caaaggcgaa gtccgtgtta
    14341 tctcaacaac ggatttccca gaagaacgtt acaaaaaagg aacggtgtta acactattcc
    14401 aagacggaaa agcacctgtg gaattaacag tcaaaagtca tcgcaaacat aaaaattttg
    14461 acttattgag ttttgaagga catccttcta tcaatgatgt ggaaaaatat cgggatggca
    14521 tattaaaagt gtcaaaagac aactctgtag atctagctga aaatgaattc tattaccatg
    14581 agatcatcgg tctgcatgta ttagaagatg gaactgagtt aggtaaagta aaagaaatct
    14641 tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc gaaaaaagct gatatattgc
    14701 ttccatatat cgcttctgtc gtcaaagaag tcgatttaga agctggagtg gtccgtgtag
    14761 aaattccaga aggactgatt gacgatgaag attgatgtat tgactttatt tccaagaatg
    14821 tttgaaggtc ctatggggga atccatcatc ggtaaggctg tagataaagg attattagat
    14881 atcaatatct ctaacttccg cgattattca gataacaaac atcagacagt agatgattat
    14941 ccatacggcg gtggagcagg tatgctgctc aaagtccagc ccatctatga taacatccaa
    15001 gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa ttcttcttga cccagctggt
    15061 aaacgattcg atcagaaaat ggcagaagaa ttttcacaag aagaacactt agtattcatt
    15121 tgtggtcatt atgagggata tgatgaacgt atccgcacat tagtgacaga tgaagtttcc
    15181 ttaggagatt atgtccttac tgggggagaa ttaggtgcga tggtcatgat cgatgcaaca
    15241 gttcggcttt tgccagatgt gttagggaat cagacttcag ctcaaacgga ttcttattca
    15301 accggtttat tggaacatcc ccaatatact cgcccggcag aatataaagg gatgaaagta
    15361 ccagaagtat tgacaaatgg aaatcataaa ttgattgaag aatggcaatt aaaagaatca
    15421 ctaagaagga cctatcaacg tcggcctgat cttttggaaa cacttgaatg gacacctcaa
    15481 atgacgaaat ttttagaaga aatcaagaaa gaagaacaag aaaaaacagc agatgaagcc
    15541 aagtgacttt ttctaaaata ttctttacag taggttgata atatgttagt attttatggt
    15601 gagtgcaaaa gcacttaact attacgatat tccgctatga gaaaagctca taagaatatt
    15661 tggaataagg agaagaaaac catgaatcca ttaatcgaag aattaacaaa agaacaatta
    15721 cgttctgaca tcccagcgtt ccgccctggt gacactgtgc gtgttcacgc aaaagttgtt
    15781 gaaggtactc gtgaacgtat ccagttattt gaaggtgttg ttatcaaacg ccgcggtgct
    15841 ggaatcagcg aaacttatac agtacgtaaa gtttctaacg gagtgggcgt tgaacgtaca
    15901 ttcccattgc atacaccacg tgttgcaaaa atcgaagtag ttcgctacgg taaagtacgt
    15961 cgtgcaaaat tgtactacct acgtgcatta cacggaaaag ctgctcgtat caaagaaatc
    16021 cgtcgttaat cattgttatc agactgagaa agaacccttg gtattcaagg gttctttttt
    16081 cttagcatgt aatttgaaca ccctgatcca gtttttttct ttaattattg gtaggggaga
    16141 ataatggatt agaataaatc tacctataag tagtagtaaa aaaaagagca ctatgataat
    16201 atctttctta agagtaaccg ctttaataaa aaatccagaa tattctaaca taaatggagt
    16261 attcttagaa tcaaaaggag aaagaagatg gtttatactt atacggagca agaaaaaatg
    16321 aaagtttgag acacattcat gaatgatgga aaagtaaaac aagtaccaag ttcaacaaaa
    16381 aagaaaaaca tcctattgaa agaagtcttg aaacgctttg accatggagt gacttataca
    16441 gaaacagagg ttaattcgat actgctgaac gtattttcta gtggcgatta tgtcgaacaa
    16501 agacgttatc taatcacatt tggctttttc aaaagaagtt cagacggtcg ggcatatcag
    16561 atgatgggaa ttgaaaatta gaagttttaa tttatactca ttgaaaaaag ttcaagtatg
    16621 cgatattggt tctacaccgc atacttgaac tttttttgtc atctgtatct ataatacaaa
    16681 gccaagaacg ttattcaaaa tatggatagc tatgataaaa gctaatgagc gattcgcagt
    16741 taaataagca atcgtcagta aaatcgttcc aggagcgtac atgaaaaaat caattggatg
    16801 cgttacatga ataaagataa ttctctttta tttgtacgaa taaataccaa aacgtacctc
    16861 ctaaaattag attcaaagaa gatagcaaag aggaaaaaga tagttctgca gcagctatag
    16921 cggcatgtgg attgctagaa ctttccaaac aactgcctgt ttcagatcct cgtcatttcg
    16981 attacgaaga gatagcaatc aaaatcttgg aagaattaca gaaaaactat acaacgaaac
    17041 gagttaacgg atcaaacggt ctgcttctcc atgccgttta tgataaaaac agcttaaaag
    17101 gtgtagatga atgtgtgatc tggggcgatt acttttatgt agaaggaatc actcgtctag
    17161 ctaaaacatg gtactgttac tggtgatgta taagagaaga ggaggattca tataatgaag
    17221 cgatggaaaa aaatgatgat tggatcaata gttttaggaa tgtcactcgt atttggtgct
    17281 tgtggtaatc aagaagacag tagtgaagaa tcagcaaatg aaattaccgt ttcgacatgg
    17341 aattatgaaa caacacctga attcaaagcg ctctttgaag cattcgaaaa gaaaacggga
    17401 atcaaagtga aagcagtaga tattgcttca gatgattatg atacgaaact caccacgatg
    17461 ctttcttctg gagacacgac agatgtattg acgatgaaaa atcttttgtc gtattcaaat
    17521 tatgctttac gagatcagtt agtcgatcaa acagaacgaa ttagagaatt agacactgat
    17581 gctgctgaag aaacatatga aatgtatgat atcgatggaa aaacatatgc attgccatat
    17641 cgaacggact tttgggtact atattacaat aagaaaatgt ttgatgatgc aggaatcgaa
    17701 tatccaaaaa atctaacttg ggacgaatat gaagatttag caaaaaaact tagtaaaaat
    17761 gacggacaag tttacggagc atatcaacat atctggcgtt cgacaatcca agctattgca
    17821 gctgctcaaa acgaggcgaa tcttgttgaa ccagattatc aatatatgac tgattattat
    17881 gatcgagcat tgaggatgca aaaagaaggc gcgcagatgg attttggcac ggctaaatca
    17941 acgaaagtaa cctatcagtc tcaatttgaa gaacaaaaag cagcaatgat gtacatggga
    18001 acttggtata tggctggcat actcgcaaac aaagaagcaa gtaagacaga agtagaatgg
    18061 ggaattacag ctattcctca gaagaaaaaa ggagaatcgg tcacgacgtt tggctcacca
    18121 acagcatttg ctgtcaataa aaactcaaag aaacaaaaag cggcgcaaga atttattgaa
    18181 tttgcagcca gtgaagaagg agcaaaagta ttagcaggag taggagtagt tccttcatat
    18241 cgtacggatg agattgatca gctttatttt aatctcgctg gaatgccaac ggatgaaatt
    18301 tctaaaaaag ctttttctcc tgatgaaatc aaacttgaat ttccgattga tacgtatggg
    18361 cctgcaatcg ataagatttt acaagaagaa tatgacttag ttttggttgg agatgaaacg
    18421 ccggaaaaag gaacggtaaa tatggagaaa cgtgtagctg cggaaaaaga ataatcatga
    18481 aaggagagaa gccaagagat aaaacactct tggtttcgtc atcgaaatgg agaatagtat
    18541 aaataagaaa gctacaaatc atttgcgtag aaaacgaacg tggatcgctt attcgtttat
    18601 cgccccgaat ttcattggtt ttttcgtttt tacattaata ccaatcctgt tttcgcttgt
    18661 actagcattt atgaaatggg attctttttc aacgccagaa tttgctggac tagataactt
    18721 tcgtaaaatg gccaacgatg agacattttg gatttctttg aaaaatactt ttttatatac
    18781 cgctgctgta gtgcctggca cacttgtttg ttcgttaggg ctagctttac tactaaatca
    18841 gaaaattaga gggatgaagc tttttcgtac gatatttttc tttccgtatg ttacttcctt
    18901 agtagcaatt gctgttgttt ggaatatgtt gtttcatcca acagtgggac ctattaatat
    18961 ctttttaaga cgatttattg aacatcctcc aggttggact tcaagttcaa attgggcgct
    19021 ttgggcaatt gtaattgtca gtatttggcg agggatgggt tattacatga ttctatacct
    19081 tgcaggacta caaagtatcc aaaaagaact atatgaagcg tcttcgctag atggagcaaa
    19141 ccgttggaaa caatttttga atgtgacatt accttcgttg agaccaacaa ccttctttgt
    19201 aacgatcatg cttgtcatca attgtttcaa ggtgtttgac cttgtgcaag tgatgacgga
    19261 tggcggccct ggtcgagcga caaatgtgct ggtttaccaa atctacaatg aagcattcaa
    19321 aaaatttgat tttggttatg cttcagctat ttcacttgtt ttgttcgtaa ttgttttggg
    19381 cgttacggtt gttcaatttt cttggaataa gcgtcgtact taggaggtgt gatatggaag
    19441 agagtgttcg aaatgaaaga aaaaaagcaa aaattcgttc aaaaaacatg ccctttattc
    19501 aatggttggg tatgattctg ctgattgtat tagctttatt gacgatcatt ccttttttat
    19561 ggatggtttc tgcttcattc aaagcaaata atgaagtgtt aacgattccg attcaatgga
    19621 tccctaaaac ttggcattta gagaattatc tggttatttg gtctcgtatt cctttagtga
    19681 cattttttaa gaatacagct tttttaagcg ttgtgatcac gttgattcag ttgtttactt
    19741 ctagttttgc tgtttacggg ttttctgaac taaattttaa agggcgcgat attttatttt
    19801 tagcatatat cggcacgatt gctgtccctt ggcagtctta tatgatcccg cagttcatta
    19861 tgatgagaaa agtgggttta acagatacgt tgtggtcgtt ggtgctatta caagcgttca
    19921 atgcttttgg tgtgttcttg ttgaagcaat attacagtag tatcccagat tctttatgtg
    19981 agagtgcgcg gatcgatggc ttatcagagt gggaaatcta tcgcaagatc attttacctc
    20041 ttacaaaacc ggcgattgcc agtttgacga tcatcacatt cgttaataca tggaacgatt
    20101 atatggggcc attcatttat ttgtcttcta cggaaaataa aacaatccag ttagggttga
    20161 aaatgtttat tgggctattt gatgcagagt acgcattaat catggctgcc tcagttgttt
    20221 ctgttcttcc tgttgctttt atatttttag cgatgcaaaa atattttgta gaagggatcg
    20281 cttcatcagg aatgaaggaa taggaggtga ttatgaaaga gcagcgtttt gacaaaaatg
    20341 tttatatgga attcttttat tggttgtatc aatcattggc aagtagcctt tgtttttggt
    20401 gtgtcaatat cttgtatata gcagctgcgt tccttttgtc gatagatgga aggaatgtct
    20461 tttcctttat tttttcttta ctttttattg gtccaggttg catcgtgatg ataggtatga
    20521 cagaagaatt agcaaaagaa aaaagttttt caccagtacg tttgttcata aagacgtttc
    20581 gccaattttg gctaaaggga tttttttatt ggctatttgc ttggatagtt agtgtgataa
    20641 tgatttttga ttgtttcttt tttatacgtt tttcttatgg aaaatggttg attccgttgt
    20701 ttgttttact tgcttgtttt acttgcttgt ttatcagttt cctttagcat caactgctgg
    20761 tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat agcgttctac
    20821 tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac aagtttgttt
    20881 ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat cgtatttggt
    20941 ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac tttataaatt
    21001 gaaactttca attaagaatg acagtttttt atgtaaaaac tgtcattctt tttcattttt
    21061 tgaaacatat ggctaaacaa atgaaataaa acatgctata cttttgaatg aaacaggttt
    21121 agaaactgta tcacttattt gtgattattt ctaactaata attaaaaata aagcataaaa
    21181 aggacgatgt tcaatggctg aaaaaatgaa acaaggttcg aaatctgtag tagaaagttt
    21241 gattaatcat catgttgatt atgtattcgg tataccaggt gcaaaaatcg atggtgtatt
    21301 taatgaatta gaggatcaag gtcctgaatt aatcgtgact cgtcacgaac aaaatgctgc
    21361 atttatggca caagcaatcg gacgtattac aggagagcca ggagtagtta tcgcaacaag
    21421 tggtcctggt gctagtaact tagctacagg tttggtaaca gcgacagcag aaggtgaccc
    21481 agttttagca attgccggac aagtaaaacg aagcgatcta ttgaagttga cccatcaaag
    21541 catggataat gcagcactgt tccagccaat cacaaaatac agtgcagaaa tccaagatcc
    21601 agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg gctaagagtt caaaaaaagg
    21661 cgcgagcttt atcagtatcc cgcaagatgt agtggatgca cctgtccaag gtaatgtcat
    21721 caagccattg agcgatccta aattaggttc tgcttctgca gatgatatcc gttacctagc
    21781 tgaacgcatt agagaagcaa aactaccggt actattagta ggtatgcgag gatcaagtga
    21841 aaaagaaacg ttagccatca ggcaattagt tgaaaagaca gcattgcctg ttgtagagac
    21901 attccaagca gctggagtga tctcacgtga attagaagcg catttctttg gtcgtgtggg
    21961 tttatttaga aaccaaccag gagatatgct tttgaaacga agtgatctag ttattgcaat
    22021 tggctatgat ccaatcgaat atgaagcaag aaactggaat gcggaaaaag atgcgcggat
    22081 cattgtgatc gatgaagcgc cagctgaaat cgatcctttt atgcagcctg aaagagaatt
    22141 gatcggtgat atctcagcca ctcttgattt attgacaggt tcattagagc ctcaacaagt
    22201 gtcagaagat gcaaaagaat atttagcatc tcttcaagca aaattaacgg agcgggacat
    22261 tgttcaatca aaaggagaag caggtatctt gcatccttta gaagttatta acacgcttca
    22321 gtcaaaagta acagatgata tgactgttac cgtagatgta ggtagtcatt atatttggat
    22381 ggcacgccac tttagaagtt atgaacctcg tcatttgtta ttcagtaatg gtatgcaaac
    22441 gcttggtgtt gcattgccat gggcgatttc tgctgcattg gtgcgtccaa atacacagat
    22501 cgtatcagtt tccggcgatg ggggattttt attctctgcc caggatttag aaacggcggt
    22561 acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat ggacactaca atatggtaga
    22621 gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta gactttggtc cagttgattt
    22681 tgtgaaatat gcagaagctt ttggcgctaa aggaatccga gctacaagtg tagaggaatt
    22741 agaaaaagct ttagaagaag gatttgcgac agaaggaccc gtaattattg atattccgat
    22801 tgattaccgt gataatgaga aattgggaga aacaatctta ccagatcaat tctattaagg
    22861 aagtgtcgac atgactgaaa aaatcttata ccagcacggg acattaggag ctttgatggc
    22921 cggcttgatg gatggaacag aaacgattgc tcatatatta gaaaaaggaa ctctgggatt
    22981 gggaacattg catgggcttg atggtgaagt catcttttta gatggcgtag cttatcaagg
    23041 aagatcagat ggctcagttg cccaattaga tggaagtgaa cttaccccct atgcagcaat
    23101 tacagatttt acgccagata ctagtttttc tgtctcaaaa actgcagatg gagaacaatt
    23161 gaaaaaagac atattagtaa gagaagccgg ggaaaaccta tttttggcag tgaagataac
    23221 tggattattc aaaaatatgc acatccgtat catgccgaag caagaaaaac cttacagaag
    23281 actagcaaaa atttcagagt ctcaaccaga attccaacaa agcaatgtcc aaggaacatt
    23341 agtcgggttc tttacgcctg aattattcca aggagttgct gcagcgggat ttcacctgca
    23401 ttttatcgat gatacacata catttggcgg acatgtaatg gattttgaag tggctgaagg
    23461 aaaagttgag attagccgca tctcgtccct tgtacagcat tttccagttg atgatccgac
    23521 ttttgttcac gaaacgattg attatgctga tttagcagca gaaatccaac aagcagaata
    23581 gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac gtatctcgtt tttttgagga
    23641 gaaaacctag cgtttacaaa aaaactgagc tataatcttc tccatagatc aaaaaggagc
    23701 ggtttttatc atgtggacag aaaaacagaa aaaagatgca tacgaaattt tattattaca
    23761 gcaacaagga ttattagaag cagaagataa ctggttagca aatttagcaa attcatctgc
    23821 attgttgaat gagactttgc ctgagactgt ctttgcagga tattatttat tcgatggtaa
    23881 tgaattgatt ttaggaccgt tccaagggcg agtttcttgc acacgtatca agatgggaaa
    23941 aggagtttgt ggagaatcag ctgaaaaaca agaaacattg atcgttgatg atgtcaaaac
    24001 ccatgcaaat tacatttcct gcgattcagc cgcacaatca gaaatcgtag tgccaatggt
    24061 aaaagaaggt aatttaatcg gtgttttaga tatcgattgc ggagtaacga aagggtatga
    24121 tgaaatcgat caagcatttc tagaaaaata tgtagatctt ttattagcaa attttaatat
    24181 aaatgctttt tcatttatta ataactaaaa tcgtctattg aaacaaaaaa gaagagaaat
    24241 caagaataaa aagagccgga aagacagtgg gcatttctgt ttttcggttt ttttattttt
    24301 ttataaaatc acaagtgtta ttgattttca taatcatatt ttaatgttat tatcatttta
    24361 aataatgaaa aaacattaag gatggatgaa atatgaataa cgaaactatc attttaggaa
    24421 aaaaatatat ttgccaacct attggcttga aacaaaaagt gattggagaa gtaatcagta
    24481 aattagaaaa ttgtgttgtg atctgcgtag acgaatatca tgacgtcgat cgcaatgaaa
    24541 tattagaaaa atgcggaaaa gtagtggcaa aatatactca cgtttatgag ttggaaacaa
    24601 cagaatatct atataactat agcaacaaat atgaacatac tttagtttca taaagattta
    24661 aataaagtgc cttcaaaagc gagaagacca agcttttgaa ggcactttat ttagttggca
    24721 gtgattgttc atgatttttg atttattcaa aaggttcgcc tagagaatct gtctctgtaa
    24781 cgaggcctgg tggagaaact cgataaaaac ctatactgcc agaactgtcc tattttcgga
    24841 tagacaaact agtagtttta aaaagatcat ccgatccaat catttcaaaa aatgcaaaac
    24901 tgatatcagg atcatttagc tcaggcttgt tatcgtaaag catttgtaaa ggttgcattt
    24961 agttaggagt aaacgcgaaa ctatcatcat tatttgctga agaagatgaa gaagctaatt
    25021 cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc tttaccctgt tttttgcaga
    25081 ggtagaaact tttatatcgg aagtttctac cggagaattt ttctcatttg tagaaattgt
    25141 tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg ttctttgatg cagaagtccc
    25201 acaagcagta agtaacaata aatttgataa actgataaac agaattcttt tcattatgta
    25261 cacactcctt atagtatcgt ttagcataca cctatgctca gtattaggca aaatcaatgc
    25321 aaaactatca agtcttttat agtatctatt agtcttagta atacatatat ggagagggtg
    25381 atatcccagt tcaaaccaga tacattggtt accatctgta ttaacgatta tgcctctaaa
    25441 cgcttttttt atgaaaaaat ttataagtga aaacgtaggt atgatattat ctagaggtaa
    25501 tttttttggg tatttaaata gttgctagga ggatagcttt tggattttta cagtaatttt
    25561 atcttaataa tagcaatatt attacttcta aatatttggt tttttgataa gagtagaaat
    25621 gcagggatag gttttagaac caaacgaagt acgtcttctg aaaaaaagtg ggtatattca
    25681 cagactattt tttacggagg ggttatttca atcagtttac tttcttcaac actttattct
    25741 tttaatgtta tagacgtttc catgtcaaat tttatatcta ttattggaat ccttatttct
    25801 gcaattatta cacaactact tcttgtgttt gaagagaagt caaaaaataa ttaaagcaat
    25861 tatgcctttt agtacaggaa ttattacttc ttacaaatgt atagcgaatg tgaagcctgc
    25921 tgttttaatt gttctagaaa aacttttgag tgaacaatta ttttatgtta ggatgaatta
    25981 atttctctag agtttataat
//
LOCUS       DBGZHO010000036        24703 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.036, whole genome shotgun sequence.
ACCESSION   DBGZHO010000036 DBGZHO010000000
VERSION     DBGZHO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.036"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(278..676)
                     /locus_tag="ACN3HL_001701"
     CDS             complement(278..676)
                     /locus_tag="ACN3HL_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HHC8006568.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(673..1446)
                     /locus_tag="ACN3HL_001702"
     CDS             complement(673..1446)
                     /locus_tag="ACN3HL_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HHC8006569.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1443..2126)
                     /locus_tag="ACN3HL_001703"
     CDS             complement(1443..2126)
                     /locus_tag="ACN3HL_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HHC8006570.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2293..3180)
                     /locus_tag="ACN3HL_001704"
     CDS             complement(2293..3180)
                     /locus_tag="ACN3HL_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006571.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3177..4046)
                     /locus_tag="ACN3HL_001705"
     CDS             complement(3177..4046)
                     /locus_tag="ACN3HL_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006572.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4183..5469)
                     /locus_tag="ACN3HL_001706"
     CDS             complement(4183..5469)
                     /locus_tag="ACN3HL_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006573.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5742..6320
                     /locus_tag="ACN3HL_001707"
     CDS             5742..6320
                     /locus_tag="ACN3HL_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8006574.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6320..7249
                     /locus_tag="ACN3HL_001708"
     CDS             6320..7249
                     /locus_tag="ACN3HL_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006575.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7246..8982
                     /locus_tag="ACN3HL_001709"
     CDS             7246..8982
                     /locus_tag="ACN3HL_001709"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHC8006576.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(9045..9881)
                     /gene="pheA"
                     /locus_tag="ACN3HL_001710"
     CDS             complement(9045..9881)
                     /gene="pheA"
                     /locus_tag="ACN3HL_001710"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HHC8006577.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9878..10387)
                     /locus_tag="ACN3HL_001711"
     CDS             complement(9878..10387)
                     /locus_tag="ACN3HL_001711"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HHC8006578.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10380..11675)
                     /gene="aroA"
                     /locus_tag="ACN3HL_001712"
     CDS             complement(10380..11675)
                     /gene="aroA"
                     /locus_tag="ACN3HL_001712"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HHC8006579.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11688..12779)
                     /locus_tag="ACN3HL_001713"
     CDS             complement(11688..12779)
                     /locus_tag="ACN3HL_001713"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HHC8006580.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12796..13962)
                     /gene="aroC"
                     /locus_tag="ACN3HL_001714"
     CDS             complement(12796..13962)
                     /gene="aroC"
                     /locus_tag="ACN3HL_001714"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HHC8006581.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13964..15028)
                     /gene="aroB"
                     /locus_tag="ACN3HL_001715"
     CDS             complement(13964..15028)
                     /gene="aroB"
                     /locus_tag="ACN3HL_001715"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HHC8006582.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(15061..16083)
                     /gene="aroF"
                     /locus_tag="ACN3HL_001716"
     CDS             complement(15061..16083)
                     /gene="aroF"
                     /locus_tag="ACN3HL_001716"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HHC8006583.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16742..17716)
                     /locus_tag="ACN3HL_001717"
     CDS             complement(16742..17716)
                     /locus_tag="ACN3HL_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HHC8006584.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17697..19580)
                     /locus_tag="ACN3HL_001718"
     CDS             complement(17697..19580)
                     /locus_tag="ACN3HL_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HHC8006585.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19598..21823)
                     /locus_tag="ACN3HL_001719"
     CDS             complement(19598..21823)
                     /locus_tag="ACN3HL_001719"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HHC8006586.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21938..22972
                     /locus_tag="ACN3HL_001720"
     CDS             21938..22972
                     /locus_tag="ACN3HL_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8006587.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(23039..24052)
                     /locus_tag="ACN3HL_001721"
     CDS             complement(23039..24052)
                     /locus_tag="ACN3HL_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8006588.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24130..24318)
                     /locus_tag="ACN3HL_001722"
     CDS             complement(24130..24318)
                     /locus_tag="ACN3HL_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HHC8006589.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7104 a         5373 c         4420 g         7806 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaaatagcat attttgaaaa gaaagtctga tgcttagagt agaatttcat aaaaatttac
      181 tatttcataa gtattcacga gaaaaataca aacaaaaaag cggaaataac gctcatccgc
      241 cttcttgttt gtgtttattt cctcttcaaa cgcttgtcta tgattcagac ttttctctat
      301 cgttattttc atctaaaagt tcttgcattc cgataatttc tcgatattga tgaatcttag
      361 tgataccaat gactttgtct acatcaatac taaaacaaat accattacct ggaatatcga
      421 tgttgatgcc ttgaccaatc gcatccatta ctttattcgt caaactatcg ggtactaatg
      481 tcaacacaat atctttttct ggcgaaatgt ccaaacctaa aaatttccct gaatcatgta
      541 caccagaacc tcttccatgt aagatcgttc cgcctgctgc acctgcttct tttgaaaagt
      601 cgataacatc ttcgcccatt cctccgtcaa cgatcgtcac aatcatgtga agattcaatg
      661 ctacaagatc tttcatttgc tttcccccaa tttttgcaat ctttcttttt cgattctgtc
      721 tttttcatct tttcgtttat aaatatatcc tagtactaaa gtggataata ttggtgtcaa
      781 tgcaatcatt gcaaccacac caaacccgtc aatgatcgga tctcttcctt caatttgtgc
      841 agcgattgcc acgctcattg ataaaataaa tgtcgaacac atcgggcccg ttgctactcc
      901 accgttatca aaagccattg ctaaaaagat cttgtccact tttcgtccta aaataaatgc
      961 tagcccgtat cctgggatca agaaataata aagagagaat ccgacgagca aacgccacat
     1021 agacaatcct actgctgcgc cgatcccaat tgaaattacc atcagcatga ttttcgatcg
     1081 gattctcccc tcgctcaatt cttcaacctg tttgatcatt acatgaatcg ccggctcagc
     1141 aaaccctact aagaacccca ttaaaaagcc aaggggaacc agtatataat tgtaaggcaa
     1201 tcccgcaata gcactgccta aatgctgtcc taccggtaca taagccatat tgactccgtg
     1261 caggaaaagg atcaacccaa tagtcgttat caagaaacct ttcataatgt caaagaaacg
     1321 ctttttgcgc atacgaaaac taatgatatt cattaaaaca aataggatta cgataggtgc
     1381 cactgccaaa atgacttcca tggtaacgat ttcgattcca tctatcactt gctgccagaa
     1441 actcattgga agatcacccc caaaatcatc acggcaagaa tcggccctaa cgaagcaata
     1501 ccgaccattc caaaactgtc attttcattt ttcttttgtt tgatcatact agtcatccct
     1561 ccggcaaggg ccaagataaa tggaacagtt actggaccag tagtcactcc ccccgaatca
     1621 aaagcaatcg gcataaattc ggaactggtg aaaaatgagg cgatcaaaac gcctatgtag
     1681 cctatagcca tcaattgata ataggatagc ttgaatacga cccgaagcag cgcaaaggct
     1741 agaaatactc cagtgccgac gctgacgatc ccaatcagca acactctgcc aatctctccg
     1801 tcagatatat catatacttg ttgtcccaaa acttgcacgg aaggttcagc aatcgtgatc
     1861 acgatcccga tagcaaatcc caaactgacc aaaacggtca aacttttctt tttgatcata
     1921 tatttcccta ctagatctcc gacttccatc atagaataat ctgctccaaa caaaaagagc
     1981 gtcattccga tcatcatgat tgccgcacca accagaaatg aagcgaggtc ttctccttct
     2041 aacggtgcaa aaacaaacgt taaaatgaca atcaggacag tcatcggcaa tatagcagca
     2101 atcacttctt taaaattttt tagcatgtat cctcctcctt tactctttaa gtttacctta
     2161 aaatgaaaga gttttcgagc acaaacttaa aacgttatca tttaattttt ctcaacataa
     2221 aataacacac gtcccaaaag tatcatttta cttggaaaaa tgactttgaa ggaacgcgct
     2281 tattgtgttt ttttatttta cagagccgat cattccttga acgaattgct tttgcaaaac
     2341 aaaaaatacg atggcagttg gtaaagtagc gatgactaat ccagccatga tcattccata
     2401 gtctggtgta taggaagcac ccatagcaga taaaacaagc ggaaccgtcc gtttatcagg
     2461 agattgcaaa gctactaagg gccataaata attgttccag ctactcatga atgtgatgat
     2521 tgcagccgcg gcataggtat ttttagccgt cggcatatac actctaaaaa aaatacttag
     2581 ttcttttaga ccgtctaatc gagcggcttc tactagatct tttggaaaag atttaacatt
     2641 ttgtcgaaag aagaagatca aaaaagcagt gctaacagat ggcaggatga caaccaagaa
     2701 actgttgatt cccaaaaccg ttccgttcaa ttgtgaaaac attcgatata aagggatcat
     2761 caatgccgca aaaggaacca tcatcgatag cagtagaata ttgaaaatta ggtcttttcg
     2821 tttactttga taaatctcaa atccatatcc tgccattgac gaaatcagca atgcaaacac
     2881 agtggtcacc aaagcgatca tcgctgaatt ccaaagggaa cgagtaaaat tcagctcatt
     2941 ggaaaacaaa ttttgaaaat tgatgatcaa gttactgcca atctttattt ttcccgatgt
     3001 gatatccacg ggtgtattcg tcattcccaa aaccatccag acaaaaggga aaatggaaat
     3061 aaatgatagg atgcttaatg ctgtatactt taatactgac ccaattgtcg aacgaagttc
     3121 taatgcttgt tttttgacgt tggggcgttc gattgtttct ttttctacca tatttttcat
     3181 cgactttctc ctcctacttt cgtttggatt atcgacaata tcacaataaa ggaaacaata
     3241 acaaaggaaa ctgctgccgc atatccaaaa ttaggcgtga atttataact caaattatag
     3301 atgtattgag atagggtggt cgttgcattt gctggtcccc cgccagtaat attttgtact
     3361 tcatcaaaaa gctgcaatgt cccgatcgtc gaagtaatgg aagtaaacaa aatgattggt
     3421 tttaaatttg ggatcgtcac tttgataaac tgctgccatt tagaagcacc gtcaatagat
     3481 gctgcttcat aaatctccga atcaatattt tgcatgcctg aaaggaaaaa aatcatattg
     3541 tatccagtcc aacgccaagt gatcgaaaga atgatcagaa ctctcgccca aattggatga
     3601 gtcaaccagc caatcggtgt gtcaatcata ccaatgccca acaacaagtt gtttacaagg
     3661 ccagattgag aaaatagact tttcatgatc agagaataac tgaccatcga agtgatacat
     3721 ggaagaaaga tagcggttcg aaacaaccct ttatatttca actttttatc atttaaaagg
     3781 ttggaaataa aaagtgctag aaacaacatg atcggtactt gtacaagtaa atacaggaat
     3841 gtattaaaaa aagctttttt aaaagttgca tctgtcaaca tccgctgata attacctaac
     3901 ccgttaaatg tcatattgac agggggacca ctttgaaaag acgtgatcaa agccaaaacc
     3961 atcggaataa aaaccatgat tgatatcaaa atgactggca agattaaaaa agcatgcccg
     4021 tttttgaata aatctttctg cttcattctt ttccctccaa ttctatcatt gattatctac
     4081 atgaaaagac aagaaagaca atatctgtaa ggcagacgtg atcttttttg tcttttcgtt
     4141 tgtctgatga aaaagcgaag aaattcactt ttttaccacc gatcaattag ccaattgtgc
     4201 ttctacttgt ttttgtgtat ctgctagtac cttgtctgtc tcttctccat tgatgattcg
     4261 atgaagagct tcagctacga ctgcttcaat tgcataggtc tcatgtccgt aattcacttc
     4321 tggtatttca gatgtccatg ttgaaaaatc gtcaaagatc ttttgaccac tgtaaaattc
     4381 agaagcttct tgataagctt cttgttcatt cgcgctaagc atcgtagata ctagtccgat
     4441 ttctttcgca agagtgccca tcagttcttc attcgaagca aacgttgctt ctaggaaatc
     4501 tttcgctgaa tcttctccag ctactccttt gatcacatac cagccagcgc cgccaaggtt
     4561 agaagcttgc gctttttgca gattttctgg aagtgcaggt attggtgcaa tcttccattt
     4621 tccagattgg ttttctgctc cttggatcgt tgaagaatac caagcgccag ttgggctaga
     4681 agctactgct cctgattgta tcgcagttac tccagcattc cagtcagagg tttgttcgac
     4741 tagatcttct ttcaaaagag tggcaaacaa ttcaagacca tactttaaag atgcattgtc
     4801 ttggatcgtg actgtctccc catcttcaga tgtataccat tctcctgcct gttgcataat
     4861 catccttact cgaccaaggt cagaaggatt gacttcagcg attttctttc ccgtcttttc
     4921 tttgacatct cgcgctactt gaatatactc gtcccacttc agattctcca tatcctcttc
     4981 tgtataacct gcttctgcca tcagatccgt acgatagaag tttgctgtta cgcccgaatc
     5041 gaaaggaaca ccgtatattt tatctcctac tttgtttacc gcaaatttat acggtgcaaa
     5101 atgatcttcc tttacaatag cagacaaatt agcgaatgca tctggataag aagtcaaata
     5161 gccttgtatc ctataatctt caatcaagac gatattgggc aatccttctg tattcccgct
     5221 cgctaaagcg gtgttcagtt tctgaacgat atcatcctga gacatcgtaa caacttctat
     5281 ctctgtttct tcgttctcat aaactttttt tgcttcattc actgctttga tattgaatgt
     5341 ctcatcccac gcccagacag tgactttttc ttctttgtct gctgtactac tagcacttcc
     5401 gcatcctgtt aagaaacctg atgctgccgc taaacaaacg actccagcaa ttaactttct
     5461 gatgttcatt tttatccgct ccttttccat ccattagttg tttacgtttg ctacattcat
     5521 cataccaaaa tttgaaaacg gtttctttat tattcagata cttcaaaaat ttctcctaaa
     5581 ataataaaaa aatacaaatc aactatgaca aaaggaataa tcttagcatc tagaccaaag
     5641 atcgaaatgg tgaggtttct ttaaaataaa aatatccttg cattttctcc tagaaataag
     5701 tatttttaaa ttacaagact attcttaagg cgggtaaaaa aatgccaata cgcgtaattc
     5761 ttatcgatga tgaacagacg attttagatg gaatgaaaca gttgatcaat tggtctgagc
     5821 acgggtttca attaataggg actttttcca gtccgctgaa agcgcttgat ttttctttgg
     5881 tacatgcaat cgatatcgtg gtcacagatg taatgatgcc tgaattaaat ggaatcgaat
     5941 tatcgcggct attaaaacag caacaacctg aaacacagat ccttatcctc tctagctatg
     6001 atgaatttga tatggttaaa gattctttta aagaaggcgt cgctgattat cttttaaagc
     6061 ctcgattgag tcctgatttt tttctaaatt ccttaactgc cgtttcacaa aaaatcaaaa
     6121 aaaagcccaa caaaagccca atcaccaatc gttatgagca gatctgcgag aatctttcac
     6181 agcagattgc tggacaaact cgtccattgc ttgaccctct tctttttgaa cacaccttgt
     6241 ttttctgtta tataccgaaa aacggccatt cagttcaaaa caaggctcta aacaaaaaca
     6301 gtcgatcacc cattcattga tggatagcga cgattcgttt actatttatc ctgtttctac
     6361 cttttcggaa gaatccggct atgtaatcaa tactgattcc aaagatacac ttaggaagtt
     6421 tgttcaaaag tttcgtcaag aagtttttcc aggtgatttt tttgttgttt ctgattcttt
     6481 tgcaatccaa gatatcaatg aaatattcca agagatcaga aattgcacca aaggacaacg
     6541 tttctatcat aagggaaaga accttgctta tcagcatgaa cttcttccgt tattaaccaa
     6601 ccacgagcag caagcaagta gttatttaac aaaaatcgtt cataaagact acgctttagc
     6661 tgtcaaagaa cttgagaatt tcttcacgac gatattggaa cagcctattg atccagctta
     6721 tttgaaacat gaggcaatca atcgtttcta tgcattactc aacgctttgg ctgacgagca
     6781 tgttgggaat gaagaacttt ctttgctcaa gatcgccctt ccttctttat tagccgatgc
     6841 tgagtatttc gaagattttt ctattcttgt caaagaaaca cttgagaaac tcacccactt
     6901 ttctgcaaat gcaaaaaaag acaatttcga tatcttgact ttgatctacg agttcgtcca
     6961 ggaaaattat gagaaagaaa tcaatttaca acttttatcc gaaaaatatc atttttcata
     7021 tagctatctc tcagccatct ttactgaaaa atttggtatc aacttttcaa aatatctaaa
     7081 aaaagtccgt atcagtaaag ccaagctctt tttgacggaa acacggctta ctttgacgga
     7141 aatctgtgag aaagtcggct ataccgaact gggttatttc tccagagttt ttaaagaaga
     7201 gacaggaatg acaccttctc aataccgtaa aggaactttt gtaaaatgag aaaaaaaatc
     7261 aaagagcatg aactctttgc caaacttctg ttcattttgt tcatcggtct ttttctgcaa
     7321 gccatcgtca tttctttgtt tatttatcat cgatcaaggg atgcctatat ccagctgttc
     7381 aatcaatcga atgatgtggt actaaaaaag attcaatctg aatttgaaag tttgaatgat
     7441 acaatcgaga atacattagc cgcttttgat tctaatccag ctgtcaaaag ctatttttcc
     7501 aatgatccag cccaacatat ggaacagctt cagcaactaa gaacaatcca aaaaatgaat
     7561 gactctcttt caaaaatcca tccaatgatc gattacgatg tattgatctt tggagaaaat
     7621 ggaagaactt ttgtcggaaa cgacatgctc actgccgtat ctgccgattc tttttttcaa
     7681 tctgcgattg ctcagagagt gaatgaacgt gctgctgata cacaaatgct ttttgcacac
     7741 cacggattga ctcttcgcga taagaaagca cccagcgtct tctttgtcaa aaaactgaaa
     7801 aatacattga atcacgttta cggatatgct gttttatcga tctcatccaa gcaactagcg
     7861 aatctttttc aatctgtagt aaatcctgag atatcgaaga tctccttcat gaacgaagaa
     7921 cagacgatca tcgcatcaaa tgaagaaaat acaattggga gccgatcaat gattttcaaa
     7981 aaactaacag taggtgaaac aacgatttca aatggacagc agttgacccg tcttcctctg
     8041 taccgccagg attgtacatt actcagtcaa gtcgatcttc attctttatc taaccaaatg
     8101 ggcgtgattt ttccgattat tttgtataat atcgtgacac ttgcttttgc tggctcattg
     8161 gtatttatgt atttggatcg acacacaaaa tcgatctacc gcttgattga ttcgctaaaa
     8221 cggctagagg aagatggctt aaaagctact gttcctgtac aaggaagcca tgaagtccaa
     8281 ttgctaggga atacgatcaa tcaattgcta agtaatgctc agcatcatta tgaacagacg
     8341 atccaagacg aaaagaagaa acgttcgctt gaaatccaaa ctatgcaagc acagatacag
     8401 ccccatttta tttataatac gctgactagc ttgaaatttt tgatttggca gaaaaaaaca
     8461 gatgaagcag ttcaaggaat cgacagtttc attactttac taagaagtac gattgggaaa
     8521 aaagaagaag tgattccagt caaggaagaa atcaaaagcg tacaaagtta catcgatctt
     8581 ttgagtatgc gatatggcga aagaatctcg gctaaaataa tgattcctga tgaactgcag
     8641 tcattatcta tgccgaatat gatccttcaa ccaattatcg aaaacgccta tcttcatgct
     8701 tttcacaata aaacgcaagg attcatcacg gtgtacggca aaacaaaaaa tcagcttctt
     8761 ttattcgaag tgattgataa cggcgatggc ttcgatactg aaaataccaa acaaaaaaat
     8821 gatcattttt caggaatcgg catcagccat gtagatgagc ggatacgcct aatgtatggc
     8881 gatgcatatg gcttaacgat ccaatcagtg attgggacag gaacgactgt aacgatttgt
     8941 ctaccgcttc ttcctaaaaa tcaatcagaa tatcaaaaat aaagaatagc caagcgctga
     9001 tttttttatt ttaagttaaa taaatcaatc agtattcttg actttcatct acgcgtctct
     9061 tctactgtca gcactggata acagcccaat atttgacttt ctcctccgag catcttgatt
     9121 tcttggagcg cattctctac taatgtcatt ggacggtcca acaacaaatc gatcacgaaa
     9181 aaatattctc ccaagctagt tttcaatggt cgggattcaa tcttacttaa gttgatttcc
     9241 cgccagccaa aagctgccag cattttatga agcatccctg gccgattagc aggtagtgtc
     9301 aagatgacac tcatttttac tggagctgac tgctggctgg tcatctttcg gtcaccgacg
     9361 atccaaaaac gtgtctggtt caactcatta tcttggatat tctcagctaa gatctccaat
     9421 ccaacatgct gtgctgtttc taatgaagca atcgctgctg cgtcttcttt cggatgttct
     9481 gctacataca ttgctgcagc agttgttgat tctgttgcta ctaaaggaac attaggataa
     9541 tgcgtttcta aaaactgttg tgattgtgct agtgcttgtg gatgtgaaag gatttttgta
     9601 atctttgttg ctggattgcc taaaagctgc tgcttgatag gaagaacgat ttcactttta
     9661 acttcgactt ctggatgttt ggaaagaaga tcgattgtgt gatgaacagc tccttccaat
     9721 gaattctcta caggaacgac agccagatcg acttgtttgc gaaacaaagc gcgcaaacaa
     9781 acagggatgg aagcatacgc agtcaattgt tctgtaggaa atagctgaca agccgcctga
     9841 taagtgaatg aactttctgg ccctagatag ctgacgttca tatgcttttg atcctttcta
     9901 taatggtatc gatgatcttt tctggtgttt gattggtcgt gttgattcga tgtgtcgcac
     9961 tttcttcata ccaagaaagt cgttgtgcca ataatgcttt tatttcttct cttgtttttc
    10021 caagagctaa aggtcgaata gacgtttcat cttgttggat acgatcaact agacagtccg
    10081 cttctgcctc taagtaaaga acaatcggct gtgtttttaa aaaacgccga ttttctgcac
    10141 tttggacaat ccctccacca gtcgcgataa ttttgtcttc atttgacagc tttcttaaaa
    10201 tatctgactc cacttttcga aagctttttt caccgtaata gtgaaaatat tcggcaatcg
    10261 acaattggat atgttcctca atctttgtat ctaaatctac atactctttt tgtaaacatt
    10321 gagctaaccc tttaccgatt gttgtttttc cagcgcccat gaaaccaatc agcaaaatgc
    10381 tagccatgag cttctcctcc tgacacaagt tctgctaaat cgtcaaaaaa tgccggataa
    10441 gagattgaaa cagcttcagc tccttctagt tcgcaaggtc catcagctat caaagcagct
    10501 acttgcagca tcataccgat tcgatgatcg cctctgctgg acacttttgc gccatgcaga
    10561 ggtgtcggcc catggatgat cagaccgtct gctgtcgctt ttatctttgc tcccattttc
    10621 tgtaattctt ctgccaccgc atcaattctg ttggtttctt ttacttttaa ttcttctgcg
    10681 tctttgatga tcgtgattcc ttctgcttga gtagccacta aagctagaat gggcaattca
    10741 tcaatcagac gcggaatgat ttctccacca atcgttgctt tcttcaaatg actcgtcttg
    10801 acacttaaat cagccgattg gttctgttca ttgtgattcg tctgggtaat cgctgcgccc
    10861 atctcctcca acacatctaa gataccagtt cttgttggat tgaccccgac attttttaac
    10921 aacagttggc tttccggaac aagaagtcct gctgctagaa agaaagcagc tgatgaaata
    10981 tcacctggaa cagttatctg ttgaccagtt aatttttgcg gtccggtcac tatgatcgtt
    11041 ttatcttcca ctgtgatcct tccgccaaat tgacgaatca tttcttccgt atggttacgg
    11101 gaacgttctt tttcaacgat tacggatgtg ccttctgctt gtaatgccgc aaacagcaaa
    11161 gcagatttga cttgcgcact ggctacaggc atattgtatc ggataggtga taaagagcgg
    11221 gttcctgtca cagtgattgg tagatactgg tcattttctt ctccttgcaa gtcagcgccc
    11281 atctcgcgta aaggttccat cactcgcccc attggacgtt tagacaacga agcatccccg
    11341 aacagagtag tcgtaaaagg ctgtccagcc aaaataccca tcaataaacg tatggtcgta
    11401 ccggagtttc ccatgtcaat tgattcggtt ggttggacaa atgagtggct accgcgacca
    11461 tgaatcttga tcacctcttc ctcttcttcg atctcgacac ctaattgttg gaaggcatgt
    11521 aaagtactca gacaatcttc tgcgcgcaaa aaattttgta tagtcgtcgt tccttcagca
    11581 attgctccaa acatgatgct gcgatgggaa attgatttat ctgctggtat cctaacagtc
    11641 cctcttaatc catgtatttg ttgtaataat tgcatttatc cagcctccta tttgatccag
    11701 caatgataac tggtattaga cataatgatt ctttttgctt gtaacaaatc ctgttggttt
    11761 ttaaaactga tttgcagtat tcctaaaata tcttccctgg tctcttggat cttcaaatta
    11821 atcaaagaaa ctcccgcttt tccgatcagt ccagttactt ctgcaataac gccaggttca
    11881 tctggcacat cgataaataa atcaaaaaag gcaggaatcg cgccttgctt atggacaggc
    11941 aactggtctc gactttcttt tgcccgattg aaaaaagaaa agatttccga ttggttctca
    12001 gtcatgatcc attctgctat ttgtgtcatt tcttgttgcc aatctgccaa tcgttccaat
    12061 aatatctgct tattgctcaa caaaatatct gtccacatga caggatctga ggaagcgatc
    12121 ctagtgatat ctcgaaagcc tcctgctgcc agttgtttgg ctcgcggata ctcttgattg
    12181 aattgttctg cctgattgac taagccagct gccagaatat gtggaaaatg acttagcatt
    12241 cctgttatac ggtcatgttc tcttgctgta agagttacat attttgcttt ggttccgcaa
    12301 aatagttctt gcagtttttc aacatctttt ttcgtctttt ccaaaggtgt aaagatgtaa
    12361 taggcatttt caaatagttt agcatctgct gcctgtatac ctgatttatg agaaccagcc
    12421 attggatgtc caccgacaaa ccgaagattt ttctgctcag cggatgtcac gacttgctgc
    12481 ttcgtactgc tgacatccgt aatgatgacg tgatcagaca agttgattct ttcaaggaca
    12541 tcaagataag ctaaggttgt acggacggga acggctaata agataacgtc tgcttgttct
    12601 gcacctgttt caaaatcact tgcaacgtaa tcaacgatct gctgttctac tgcttgctca
    12661 cgggtttttg actgactatc ccaaccaact actatcagtt ctggattggt ctgacgaata
    12721 caaagtgcca tagaagcacc aatcagtcca agccccacga taaaaacatg ttgtgccatc
    12781 ttatttgccc cctttttagt aatgtttcaa gtagtcacgg tactccttca ctgcagcttt
    12841 caactcaaca agcgaatcac ttgggaattt tgacaatagc tctgtcgcta ccacagtggc
    12901 tacaacattt tccgcaacga cgctagctgc aggaactgct gtactatccg aacgttctac
    12961 acttgctttg taaggttctt ttgtatcgat atcaacactt tgaagtggct tgtacaatgt
    13021 aggaatgggt ttcatgaccc cgcgaatgac aagtggttcg ccattggtca ttccgccttc
    13081 gaagccgcct agattattgg tacgtcggaa atagcctctt tcttcttccc ataggatctc
    13141 atccatcact tctgagcctg gtaatgaacc agaagtgaat ccgaccccaa attctacgcc
    13201 tttaaaggca ttgatactaa ccacagcttg tgcgattttg gcatctagct tcgtgtccca
    13261 ttgtacgtag cttcctaatc cagctggaac gcctccaacg agcacttcta caattcctcc
    13321 gatcgtatct ccatttttct ttgtctgatc gatcaaatct tttattcttt gctcaactgc
    13381 tggatcaaca actcgtactt ctgacgcttc agaaatttct ttgatttctt gaatcgagat
    13441 atttccaggt atttctgctt ggattccacc aagacaaatc acgtgtcctg ctacgatgat
    13501 gtcaagttct tccagaattt tcttggcaat tgcgccgatt gctacacgca tggtcgtctc
    13561 tcttgcagag gaccgttcaa gcacattccg aagatctcga tgatggtatt tcataccgcc
    13621 taccaaatcc gcgtgtcctg gacgcggacg tgcaactcgc cgcagtgatt ggtctttttc
    13681 aggcacttct gctacagaca tgacagttgt ccaatttttc caatctttat tttctaccac
    13741 taaagtgaca ggtgaaccaa ttgttttgcc gtgacggatg ccagacgtga tccgaacacg
    13801 atctttttcg atcttcatcc ttcctcctct gccgtaacca gcttgtctgc gagcgagttc
    13861 gtgattgatt tcttcttctg acagaggtaa tcctgctggt agtccttcaa taatggctgt
    13921 taattctggt ccatgggatt ctcccgcagt catataacgc atcttacagt cctcctaagt
    13981 aatctttgaa tgtctctgtg ggaacaggaa cgatttttgc ttgcccaatc ttttctagca
    14041 agatgatatt caattggctt cctcttgctt tcttatcatg ggttatcgcg tggaataatt
    14101 catctggatg acttagatcg tacgtaatcg gcagatggaa tttttgaagt atcctttcta
    14161 aagcagctgt cgatccagtt ggagacaagc cgattttttc tgcatgagaa gtgatggcta
    14221 ccattccaat agctactcct tctccatgac tgactacccc atatcctgct gtattttcaa
    14281 ttgcatggcc aattgtatga ccaaaattta aaataagtcg atttccttgg tcaaagacat
    14341 cttcttccac tacttttcgt ttgatttcca acgtagcagt aatgattgga acagcatgtt
    14401 ccagaagatc tttttcgtct ttcagctcgt tcagctgttt ccaaagcgtt gcatctgcta
    14461 tagctgctga tttgatgatt tcagcgattc cttctcgtaa acgacgtacc ggcaaagttt
    14521 ttagaacctc aggatcaatc aatacaccag ctggctggct aaatgttccg acaaggtttt
    14581 tcgctttgtt tgtattgact gctgtcttcc cgccaatact agaatctact tgtgcaagta
    14641 gcgtagtcgg aatttgaacg aaatggatcc cacgcatgaa cgtcgaggcc acgaatgctg
    14701 ctagatcacc caccattcct ccaccaagtg caagtatccc atcgctgcgg gtaaaatcat
    14761 tatctgctaa aaaatcgtat aactcagctg cttgttctaa agatttactg gtctcacccg
    14821 ccggtacgat tgaaaggact ggttcaaaat tagcttgtct caattggaac atgatttttt
    14881 ctgcatatag tggagcaacg tttgtatcag tgatcacagc tactttttga ggtctccaaa
    14941 tcgtttgaag ccatgatcca gcctgttcta gtgcgccttt ttcaatatga atatcgtatt
    15001 tttggttatc aacatgtaca gtaagcattc gtttcacttc tttcttttaa aaagctggaa
    15061 ttaatcgagt gtctgaatct tttccattgc ttctttcatg atcgcaactt ctttcatcat
    15121 gcgtgagtaa gtcttttcat tcaacgattg gggaccgtct gaccaagcat ttgcaggatc
    15181 aggatggatc tctacgatca tgccatctgc tccgcttgcc acacccgcac gagccattgg
    15241 tggtacaagt tcccaaattc ctgtaccatg acttggatca acaatcacag ggaaatgagt
    15301 taattttttc atcaatggga cagcacttaa atcaaacgta ttacgtgtcg ctgtttcgta
    15361 agtccgaatc ccacgttcga taaaaatgac aggagatttg tcttcgactg caatgtattc
    15421 tgcagcatta agccattcat tgatcgtacc ggaaattcca cgtttcaatc caacaggttt
    15481 acctgtttta ccgacagcag atagcagttt aaaattttgc atattacgtg cgccaatctg
    15541 taggatatcg ctgtactcag ccaccatatc gatatgccct tcatccatca cttcagtaat
    15601 cactttcatt ccaaattcat cagccgcttg acggatgtat ttcaatcctt cttcttctaa
    15661 accttggaaa gcatatggag aagtacgtgg tttgaaggca ccacctcgca gaatttttgc
    15721 gcccccggct ttggccattc gcgcacattc tctgatttgg tctaatcctt cgatagaaca
    15781 aggaccagcc atcgtcacga aactgccgtc accaattttt actccgtcta catccacgac
    15841 tgtattgcca ggatggaatt ctcgagaagt caatttgtat gtgtttaaaa tacgcacagc
    15901 attttctact ccttcatagc gtgtaaatgc tccttcttgt aaacttcgcg tatcaccttt
    15961 tagtccaatc actactcgtt ctgttccttg atcgattgag actttgaatc cttctttttc
    16021 gatatgatcg acgacttttt ttatttgttc ttccgttgct tcttttttca taattactat
    16081 cattgttttt cccgctttct tttgtttact tatctatctt ggctgatttt ctctactttt
    16141 tcaaggtggt tttacattaa ttcctactaa atgaccgtgt cctgttgttc tcattttcgc
    16201 tccttctttc ctacttatga cccagataat caacaaaaaa agatgtccct gtaggaaatt
    16261 gcctctacag tgaacatctt caacgagcct taaaaagcgc tgcaaaaata taaaatagcc
    16321 actatagatg aatttctcta cgtggctgta agtcgtgttt aaaaatcttt agccatcata
    16381 gatacaaacc tggtttgttt gtacccacga agtcatgaat acaaacctat ctaaaatagc
    16441 taaagtaata cgtattcagt tttgtaagtt ttctagattt cataaaaaat cgctccaaac
    16501 tgatgtaaga attgtaccta gtatagacat aaaaaaatcg actgtcaatc atttttatga
    16561 aacttttttt aattttctga tagttaactt tgtttttcag aaaaataaca attggtttta
    16621 ttgaagaaaa tagtcatgaa caaaagtatc tgagaacttt tttactctct tgttcatgac
    16681 atatagaata aagcagcttt gtcttgtaaa ctccgttttt caaataataa tctaaagatt
    16741 gctactgaat aataaagccg atttcatggt cctcttcgct gctgattcgg taaggtgact
    16801 caacatccgc tccccagcta ttgatacccc cgactcctct tacttttgca aaaatcgtaa
    16861 gaaccgttcg tctttctggc ggtagttctt ctatatgtgt tgcctgttcc agttcttctg
    16921 ctttgaatgg taaagcggaa aaagcaaatg gcgtatcctg ctgttcaaat cgcaacgaaa
    16981 aatcttcttg atctttatcc gtattatcca acgtttgatt tcttgttagt tctacccatt
    17041 tcgtttccat atgcatgccg cattcttggg gaacaaggta tggggaaacg gggagtcctg
    17101 ccactttata aataccttcg acaccaccag ccatccgatc cggatatgtt tcccctgata
    17161 ggccttcata ctcaaaaaat tttgctttcg ttggcataat gaaccttaaa cccaatgcgg
    17221 gtaattccgg taatcctttt tgtccataat aatgcatatt gacaagcatt ttaccctctc
    17281 cagcgatttg gtaggaaatt gtcacttggg tttttggtac tgtgttgatt tccagtgtaa
    17341 aaatgatttc aaccgtttca gcgtattcat tacttgaata ttgattattt actggagcaa
    17401 tcggcaaatc gatcttttta ttgtccacca gtacttctat ttctttgact tttggataca
    17461 atccggctcc taaccacata ccggatttaa atccaaatcc gctacctctg tcattatcgg
    17521 tcgttgctcg ccaaaaaact ggaagtgttt cccggtatag ccattctttt ccgtttttat
    17581 tgagcgattc cagtccgcct cttgtataag aaaaaatata atgcgtattc cccgatttga
    17641 cacctaatgt acagtcgccg aagacgattg caactttttc cgtatccata tgacttttat
    17701 ttactgtatt tttcataata atatcttacc tcctgcatgg cgggtttttc ttgtccatct
    17761 gcaaaaacga tcccattccc tgagaattca tagtcacttg gtttatcgtc aaagtcaccg
    17821 ccatagcgca tcacttctct gcctgtgatt ggatcagtca cttggatcgc ctgatcttta
    17881 aaatcccata tatagcctcc ttggtacatt tcataacgat caagcaacgt catgtaagaa
    17941 tccattccac ctaacgaatt ccccatgtca tgcatatatt cacataagat gaacggtttt
    18001 tccgctttat tttcaaggta gtcaatgatc tcttctggtg gcgcatacat gcagcttttt
    18061 acatctgaaa tcgaatcttc gaatgctgga tttggaaaat tcccttcata atggacaagt
    18121 cgatcggggt ctactttttt gaagtaatcg ttcatttgtc gaatgttttc ttccgcataa
    18181 gattcatttc caagagacca aaaaagaata cttggatggt tttttaatgt ttcgaaattc
    18241 gtttttgctc gatcaagaac agccgcctgc cactgaggta ctgcacctgg tacgttgtaa
    18301 gaaggctcaa atgcgcccat tttttgccat gagccatggg attcgaggtt cgtttccgcc
    18361 atcacatgga ttcctgcttg gtcgcataaa taataccaag tgatctggtt ggggtaatga
    18421 gatgtccgta cgccgttgat ctttgcattt tttatgatag ccaaatcttt ttccatatct
    18481 tctatagtga tggcgcgtcc ttttttcgga tgccactcat gtcgatttac cccgttgata
    18541 atcatccgtt ttccattgaa gtagatgatt ttatctttga tttcgatttt acgaaaaccg
    18601 aaggaatagt caatatactc cgttactctt ttttcttcgt ctatcgtctc caattcaagc
    18661 ttatataaat tgggctgaaa atgcccccac agtgccacat tttcaaatcc atcgatgcga
    18721 atcgtcattt gctcttttaa cggatattgc tgttgataga tttccttccc atcaggatct
    18781 agtatcgcta cattcagctg actgtttttg gctacttgct caaaagacaa atctacttca
    18841 agtttgccat tttgacattt gtcatctaag cgaggtttga tccaaagatc ttctaaatgg
    18901 ttttgtcctc gagcaactaa gaagacatct ctgaagatcc caaaaaatcg gaaaaagtcc
    18961 tgatcttcca agaatgcagc tgtacttctt ttgtaaacct ccacagctag aatattttct
    19021 tcttccaaat aaggtgttaa atcaaattca gacggagtga acgaatcttc ggcatacccg
    19081 ataaaatgac cattcaacca aataaacatt gcttgttcta caccagcaaa atgaatcgag
    19141 atttgttttc cctttagacc ttcttctaat cgaaaagtcg tcaaatacga accaaccgga
    19201 ttgtctttag cagctgaaaa gatcccttcc gcctctttct cagggcttgt cgtgaaaggg
    19261 ggacggcgaa atacatgtcc ctcccacgga tacatcgtat tgatgtaatg gatcttgtca
    19321 taatttgcta attcaatatg actaggaaca gtgatttcat caaaagaaca ggcatcaaaa
    19381 tcttttttat aaaatgtttt tggtcgtacc gaaggatttg gcgaataaca aaaacgccat
    19441 gatccattta aagactgttt aagggaggat gtggtttcta cttcttccct tgttgcataa
    19501 caaacatgat cgctatgtgc atttgattgg ttcactctaa aaacttgtgg atcatctaac
    19561 cattttatat ttgctttcat acttttttcc ttctctctca taactttttg aaatgaagca
    19621 gttctgtttg gaaatcacct tgaaaatcgg ggaagtaaag tccaactgtc atcaattcgg
    19681 cccccgaaaa tatccgcttc gaggtctgtt cctgataaag tgcctcatca tctaacccca
    19741 tcagatatac ttcatggaac gctggttgag ctgaagctag tatcctccct aaaaacacaa
    19801 tagcttcatc ttgtttagga gacacaaaca tccatgcggc aatattttct tcaaaaggac
    19861 tcgccaaacg ataataatgg ccatactgga tcaccggacg aatcgtttga taggatataa
    19921 tttggtcttt tacttgcttt ttttcttcag gagacagctt tgtcaaatcc agttcataac
    19981 caaaaacagc gctcatagct gtttctcctc ttgttttcaa cgaagtagat ctgtcggtct
    20041 gatgatttgg tacagctgat acatgagctg tgatggacga aatcggataa gcaaggcttg
    20101 ttccatattg gattttcata cgctccactg catccgtgtt atcacttgtc catgactgcg
    20161 gcatataata aataaacccg gcatcaaacc gtccacctcc accagaacag ccttcccata
    20221 agatttccgg ataatcagtt gtcaaatgtt caagtagttc ataaagcccg agcatataac
    20281 gatgcgctac ttctccttgt ctctgtgggt caagggtaat cgaatagaca tctgaaagcg
    20341 aacggttcat atcccatttg atgtagtcaa gaggaatcgt atctaaaatc tttctcattt
    20401 gtttctcaat cgtctgccga acatctaacc ttgtaaaatc cagtacatgt tgtgatctgg
    20461 aagcagaagg cattctacct ggctcctgca taagaaaatc aggatgtgtt cgatacagtt
    20521 cagaatcaac cgagatcatt tcaggttcaa accataaacc aaatttcaat cctttgctat
    20581 gagcataatc tgctatttca cgtaatccat ttgtcaactt gccttcatac tcgaaccagt
    20641 ctcctaatga agaattgtcc gcatctcttt ttccaaacca gccatcatct aatacgaaca
    20701 tttcgatgcc tagctccttt gcttcatcaa tgatcgcctt gattttttca ctattgaagt
    20761 caaagtaagt ggcttcccag ttattgacca gaatcggccg ttcagcaaat tgatgacgac
    20821 ctcttgcgat tctttcacgt agcaactcat ggtggatctg actcattttg ttcaatccct
    20881 gacttgagta agaaaggatc atttcaggtg tttgaaaaga ctggcctgca ttcaattccc
    20941 acgaaaaacg atggctgttg atcccaccga cgactctcaa ttgattgatc tgatcttttt
    21001 caagttcgaa agaatggttg ccggaataaa caaattgaag tccgatcgct tctccagtat
    21061 tttctgtcgt atgatgatga actaaagcaa taaagttatt catatggtga ctgctcgttc
    21121 ctcgacggct ttcaaatact tttgttccag ataaaacaga ttgccgtgaa atctgtcttt
    21181 cattgacatg tgctcctggc aaagcaatga cttcatcaaa tcgcctagta tgggcaaagt
    21241 ctagctggaa actagccgct ttttctagtt tgattgtttc tccggtttca tttcttatct
    21301 ttacagatcg tgtgatcact gctctatcag taaatatggt atagaacaaa tcgaaataaa
    21361 tcgctgtttc tctatcctta agtgaaatca ccaacgtttg tgcctctgac ttgtccatca
    21421 cataagtttg aggcaagcct tcgatctctg gcttcccatc tgtaatataa tggctgtcat
    21481 atctcagatc cagtaagtct gatccattct tgcgctgaat gatcgatgcg ggcgttcgaa
    21541 agtccatgct gccatgagaa gagtattctt gcggtagtgt atctttcgac agagaccggt
    21601 caggatttaa gggaacattt cctgaaaatc cacgatctct tcggggataa tttttattgt
    21661 ctttgtactg cttgactggt ttgccaaaat aaatatgcgc caatacattg ctttcttcta
    21721 tctttatcag ataagaaaga aatgtatttc gtaaatggaa gactcggctc ttttcatcaa
    21781 ataagatgaa atttttatct gtttttctat gcgtaatatc catcatttca ctcccaacaa
    21841 aacggaaacc gtttactttt ttttataatt cctgtatact gtttactaaa caattttgtc
    21901 aataaaaatt ttttattttt ttgaggagtg tgtaaaaatg gttggaatta gagatgtcgc
    21961 acgaaaggca aatgtctctc ctgctacagt ttcccgtgtg ttgaataacg atcagacgat
    22021 ccatgtggct cagactactc ggcaacggat agtagaggca gctgctgcgt tggattatga
    22081 catcagtact cgtaaatata tcaaaaagag aatgccttcg attggtgtga tctctacgat
    22141 cggcaaagcg agcgaagaac aggatatcta ttacaaacat ttgcgagtag ggatggaaga
    22201 agaagctcga cgtctgcatt tagggatgaa tcgaatctat aatctatctg ataatcctaa
    22261 acaatgggaa gatctagatc agttaggtgc ggtgatcgtt gttgggactg ttacgaaaga
    22321 atcgattacc gccttgttaa aacaaaacat gcaaatagtc gtcgtggata accctgacat
    22381 ccagcaagag gtcgatatgg tgtatgcaga tcttgaacgg atgactaaaa ccgtactgga
    22441 attgttctta gaaaatggtc ataaaagaat agcctatatc gggggatata aagtcgatat
    22501 ggatgaattc ggtgggaagc agatttctat aaatgaaaag aggatgcgtg cctatcagca
    22561 ttttatgatc gatcatcact tagaaaaata tatgtcttat catctaggtg gctggacaga
    22621 aaaacaaggt gaggtacttg cgactaatct attagaaaat gaatcccctc ttcctactgc
    22681 cattcttgtc gggagcgatc caatggcaat tggtgtctat cgggcattga aacaaaaaaa
    22741 tatccaaatt ggagaagaga ttgttgtagc aagctttgat aatatcgaga caatcgcaaa
    22801 cctctcccct ggcttgacca gtgttcaaat caatgcgaaa tcaattgggc aagcagctgt
    22861 tcgaatggca ttggagcgaa ttgacggtat acgggacgaa ccaatcattt tgacttatcc
    22921 tgcacgattg attgttaggg aaagttttat cccaagaaca aaaaggtatt gaaagagagg
    22981 ttgtgaaaag ccgcttcgtt tcttcatact caaaacgaaa cggctttttc acaacctctt
    23041 acttatactt attcacaaaa tccaatgtct gctggtaaca attttgcgat tcttttagcg
    23101 tgtaatcaaa ttggtattca tgggtaatct ctttttttgt atctgtataa aacaaggatt
    23161 gcacgggtac ctttaattct gtcaaccgat tttctaatgc ttgaccttgc tcctggaatg
    23221 agtatgcatt tccgtcagtt atatacgttg gcggaaattc cttagaaaca tggtcagcca
    23281 cactagcttc tttcaattgc tcactcgttt tccaatcttt tgttccaatc aacgaccacg
    23341 caacggtttt gacgaaaaac ttcataaatc gatcatccga atgctgctgt gctgttagct
    23401 tcaaatcaac aggtccgcaa taagaaatgg ttcctttcag actatctttt ggaagtagct
    23461 gtttgatttt catttgttta gcatacgcat cattcgtttg tatagctgca tattgcaatg
    23521 cgatttgtga acctgcacta tctccaccaa aaaataattg ttccatgtct agcaatttgt
    23581 cgtctttttc ttcagctaat aaatctttga tcagttcatt cacttgaaga acttgattag
    23641 ggtattctga atcaggcgct aattcataat tcatcgcaac cactgcgatg ttggcgtctg
    23701 aaactaattt tgtcgcaaat tctttgacac ccgatttatc tccgccgacg aatcctccac
    23761 catgtaccca aaatagaaca ggaacaggcc ccttgctgtt ttttggatag tagatgtcat
    23821 aagtattctc tttatacttg gactcatacg tcaaatctgt ttttttcgcc acgttttttt
    23881 ctgcttgatc gaacgttttt ttatcagtga tttgaacagt atttgaaaac atatggttga
    23941 tcaagaatgc tccaggtctg ggggaaagct ggaaggcaag aaagattgca aacgcgatcc
    24001 caagaatgat tccgaagaac catccgataa atttaagaat tttctttttc ataaggctcc
    24061 ctcagtagtt agtattaagc attctgatta taccatagtg ttatttccta tcaagctctc
    24121 ctagatgatt taatgatttt ccccaaactt cttctgcaat gcttttgaca aaagaaattt
    24181 tttccattgt tcttcaaaca aaacattttc ttcttctgtt gaagcaaatc cacattgagg
    24241 acttaagcac aaacgatcca aaggcagata tcgtgtcgct tcgtagatcc ggtcaatcac
    24301 ttgctggtgc tcttccattt cgccattttt cgttacagtc aaaatctaag acaactaatt
    24361 tatcttcaga gactttctct aaaagaacaa aactcccagc acgttcacta tcgtattcta
    24421 aataataggc acggacattt tcttgagtaa aataatgggt ctgctacgtc gtcatccccc
    24481 ctgatgccgc caaaatcgaa taataatttc cgcgtcaaac atgtatattt agtgttgaat
    24541 catttgagaa tatgaaaata aaaatctttt tgatcaatca gttaatcaaa ttgaaataac
    24601 gaaaaatctg agacagaatg acgttcattc tgacccagat ttgattttgc acaactcaac
    24661 agtccttatt ggcaaatcgc caaaataatg tagactaact aaa
//
LOCUS       DBGZHO010000037        24437 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.037, whole genome shotgun sequence.
ACCESSION   DBGZHO010000037 DBGZHO010000000
VERSION     DBGZHO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.037"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(369..1487)
                     /locus_tag="ACN3HL_001723"
     CDS             complement(369..1487)
                     /locus_tag="ACN3HL_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006590.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1720..1842
                     /locus_tag="ACN3HL_001724"
     CDS             1720..1842
                     /locus_tag="ACN3HL_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006591.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1958..3265
                     /locus_tag="ACN3HL_001725"
     CDS             1958..3265
                     /locus_tag="ACN3HL_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HHC8006592.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3384..4583
                     /locus_tag="ACN3HL_001726"
     CDS             3384..4583
                     /locus_tag="ACN3HL_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HHC8006593.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4610..5878)
                     /locus_tag="ACN3HL_001727"
     CDS             complement(4610..5878)
                     /locus_tag="ACN3HL_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HHC8006594.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5933..5999)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6041..6687)
                     /locus_tag="ACN3HL_001728"
                     /pseudo
     CDS             complement(6041..6687)
                     /locus_tag="ACN3HL_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7095..7598)
                     /locus_tag="ACN3HL_001729"
     CDS             complement(7095..7598)
                     /locus_tag="ACN3HL_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHC8006595.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7721..8485)
                     /locus_tag="ACN3HL_001730"
     CDS             complement(7721..8485)
                     /locus_tag="ACN3HL_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HHC8006596.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8592..8867
                     /locus_tag="ACN3HL_001731"
     CDS             8592..8867
                     /locus_tag="ACN3HL_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HHC8006597.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9583..10536
                     /gene="yidC"
                     /locus_tag="ACN3HL_001732"
     CDS             9583..10536
                     /gene="yidC"
                     /locus_tag="ACN3HL_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HHC8006598.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10658..11867
                     /locus_tag="ACN3HL_001733"
                     /pseudo
     CDS             10658..11867
                     /locus_tag="ACN3HL_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(11912..12312)
                     /locus_tag="ACN3HL_001734"
                     /pseudo
     CDS             complement(11912..12312)
                     /locus_tag="ACN3HL_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723846.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(12559..12993)
                     /gene="tnpA"
                     /locus_tag="ACN3HL_001735"
                     /pseudo
     CDS             complement(12559..12993)
                     /gene="tnpA"
                     /locus_tag="ACN3HL_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13171..13537)
                     /locus_tag="ACN3HL_001736"
                     /pseudo
     CDS             complement(13171..13537)
                     /locus_tag="ACN3HL_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(13551..13836)
                     /locus_tag="ACN3HL_001737"
                     /pseudo
     CDS             complement(13551..13836)
                     /locus_tag="ACN3HL_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13845..14036)
                     /locus_tag="ACN3HL_001738"
                     /pseudo
     CDS             complement(13845..14036)
                     /locus_tag="ACN3HL_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14036..14512)
                     /locus_tag="ACN3HL_001739"
                     /pseudo
     CDS             complement(14036..14512)
                     /locus_tag="ACN3HL_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14980..15333)
                     /locus_tag="ACN3HL_001740"
     CDS             complement(14980..15333)
                     /locus_tag="ACN3HL_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006599.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            complement(15461..15871)
                     /locus_tag="ACN3HL_001741"
     CDS             complement(15461..15871)
                     /locus_tag="ACN3HL_001741"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006600.1"
                     /translation="MEEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSN
                     LWFRQEISIAEIEDAVLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKN
                     ISYLKVYTATPPKKPTPPRFQSNGWSLFFSHKSA"
     gene            16030..16221
                     /locus_tag="ACN3HL_001742"
     CDS             16030..16221
                     /locus_tag="ACN3HL_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006601.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCEKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            complement(16263..17129)
                     /locus_tag="ACN3HL_001743"
     CDS             complement(16263..17129)
                     /locus_tag="ACN3HL_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHC8006602.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(17153..18805)
                     /locus_tag="ACN3HL_001744"
     CDS             complement(17153..18805)
                     /locus_tag="ACN3HL_001744"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HHC8006603.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            complement(18810..19604)
                     /locus_tag="ACN3HL_001745"
     CDS             complement(18810..19604)
                     /locus_tag="ACN3HL_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I phosphomannose isomerase catalytic
                     subunit"
                     /protein_id="HHC8006604.1"
                     /translation="MTLTEVLQEHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPT
                     DEYAIEKENGQLGKTEMWYVLDASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKK
                     NDVFFIEAGTIHAIGAGALIAEIQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVAN
                     LKGLSEPKQPLRVLKYRAGVAAELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVL
                     LCVNGCGTVRFDNESLDIYKGDCLFVPADSTEISIHGSIQFLDVRG"
     gene            complement(19796..21109)
                     /locus_tag="ACN3HL_001746"
     CDS             complement(19796..21109)
                     /locus_tag="ACN3HL_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HHC8006605.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            complement(21177..22121)
                     /locus_tag="ACN3HL_001747"
     CDS             complement(21177..22121)
                     /locus_tag="ACN3HL_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase family protein"
                     /protein_id="HHC8006606.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            complement(22158..23243)
                     /locus_tag="ACN3HL_001748"
     CDS             complement(22158..23243)
                     /locus_tag="ACN3HL_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHC8006607.1"
                     /translation="MNKHICFYLSSHGFGHIARNLPIIMATLCRCEAKITLVCGANHL
                     DFAKRNLEQELPKELIDRVRYRPINTDIGLINREGTLLVDTGKLTEICVYFLAKVPSL
                     AKTEAEWLKREAVSAVLCDMPIWAMDACDMAGVPFLYVGNFTWTELYREFLPEHIWKE
                     YAKRYGKIQHTMLYALNNEEMLEFLQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVF
                     VALGMSARFKQPIDVSHAPYDFITTLGVPLVGENVTVISNSTPNTQDYIAAADYVITK
                     AGWGTVAECILAQRPMALFARDTVLEDRTTICKLQKLGLAISVTPENLHRVERVIEDL
                     KQLDTSNFDTFYDAASEIADKLISLMQ"
     gene            complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="ACN3HL_001749"
     CDS             complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="ACN3HL_001749"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HHC8006608.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
BASE COUNT         6952 a         5537 c         4651 g         7297 t
ORIGIN      
        1 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
       61 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
      121 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca ccaaacaaaa
      181 aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca gctttttcac
      241 aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa aaacggaaaa
      301 atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca ctgatttcac
      361 aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc atctttttga
      421 tccaaaataa acactttccc gccattaatg atcacatcat ctgctaatgc attcaacact
      481 tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa gtttgacgta
      541 gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc aactaactga
      601 tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc tgcgagttca
      661 cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc aggagaagca
      721 gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa catcgtctga
      781 ttttctggta atgcaaataa ataaatcggc cattgttcag gattttcgaa agaatccttc
      841 aagtacgtat caacagcttg gtaatagttg acccaatcga tctctacttc ttcatctttt
      901 ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt agaagagaag
      961 ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac cggtgcccct
     1021 tctggtagag atacttcttt tacttgtttg ttgctgacct catacaattt catggagtcg
     1081 cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat aatagccagt
     1141 aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa acgatggata
     1201 taggtctggt cagcagttat aatgaccgct acactcgtag ttgcactacg ccaaaacgaa
     1261 ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg ttcggaatat
     1321 tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat ctgatctttt
     1381 tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg tcctttagcg
     1441 ccttctgaag tcaattgtgt caataattct ttatcctttt ttgccataaa cgtacccctc
     1501 ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt tttccataca
     1561 ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc tattttttta
     1621 agttatcttc ataatttcct caattattta gccccagtct tcaactattc ttcatgaaat
     1681 gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat tatgattttc
     1741 agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt agatgcggaa
     1801 acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaacttccat aacgcgcgtt
     1861 cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat aaaattttaa
     1921 tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa aaacacgtct
     1981 agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag ctgttgctgt
     2041 gcaagctgaa gatacgttca aagtaaatgc aaaagcagct tttgctgtag atgcgcaaag
     2101 cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt caatcacaaa
     2161 aatcatcggt ctttacatcg tccttgatca agtaaaagaa ggaaaactgt catggggtga
     2221 taaagtttcg atttcagatt atgcagaaaa tttgagtatc accccagatt tatcgaatgt
     2281 tcctttgcat aaagaaaaca cctacactgt caaagaatta ttcgactctg caatcatcca
     2341 gtcagccaat gcttcaatgg tggccttggc agaaaaaatc tctggcagcg aagctaaatt
     2401 cactgaacga atgaaagaac aattgaaaga ttggggaatc aaagatgcaa caatcgttaa
     2461 tgcatcagga ttgaacaact cttatcttgg cgaaaaccga ccagaaggca ctggagaaaa
     2521 cgacgaaaat caaatgtctg ctcaagatgt ggccatcgtt gcccgccatt tgatcttgga
     2581 tttcccagaa atactggatg tatcaagtac tacgacccaa atgtttggcg aaaatacgca
     2641 atcaccagtg gaaatggtca actggaactg gatgctccca ggattcgtta attacaagga
     2701 aggcgtggac ggattaaaaa ctggtacgac tgagcttgca ggtgcttgtt tcgttggtac
     2761 gatcactaaa aacgatcaac ggatcatcac tgtcgtattg aatgcggacg gccatgcgga
     2821 aaacccgagt gcccgcttca atgaaacaga ccgtttgatg gactactgct atgacaattg
     2881 gtcagaaaaa gagctcggaa aagctaacgc aagtattcct agtctaaaaa ccattgatgt
     2941 aaaagacgga aaagaatcaa cagttcctgt tgtgcttaaa agccctgtaa aagtatgggt
     3001 acgaaacgat atggatactg gcaaattaac gatcacgcca acacttgaca agaagcaagt
     3061 cactgacaat gagatccaag cacctatgga taaaggtaca aaaatcggta ccgctacgat
     3121 caccttggca gacgataaat taggctattt agaagacaac aatgcaccat caacagagat
     3181 cattacggat aaaacagtgg aaaaagcgaa tatattcgtg attggctggc gacgcgtcgc
     3241 agaatttttc ggcaacttgt tttaattgaa caataagaaa aacatctttc catcggaaag
     3301 atgttttttt gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg
     3361 tataagaaaa aggagttgaa tttatgaatc taaccagaga tctgatcttt ttagttctct
     3421 atcttattgg ggtattctct atcgtttatt ggcgaaaaca gaagaaggat ccttccttgt
     3481 tcttttacgg cagtacgtgg acatttacgg taatcttaac ttattttgtc gtgttggaaa
     3541 ttttttattc gaccttttat tttttgattc cattgttgtt ctttagtatc tttgcttttt
     3601 cttatttcac agaaaaacga aggctactga atggtctttt attcaatgtt ttactcatca
     3661 gtttcggcat ctacttgttt gtcttgctgt atgaaacgca aaatattttt cttggcggac
     3721 tgatcgcctt gatcacgatt ccattgctac ttgtcctttt atttggtatt tatggattga
     3781 ttgtttttct tttttggaac ggggtcacag ttttacgtag agaatcgcat tcattagcta
     3841 atcttttaac gttgatacta gccatttttc ttacactgtt tcttgttttt gactttttct
     3901 tgttaaaata tttgccgcaa tggataaatg ctttgttttt ctgcgttccc ctgatcttga
     3961 tctatctatt tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc
     4021 ggcctcgata caatcaagac ttcatcgttg tgttaggcgc tggattgatc aatggagaaa
     4081 cagtttctcc tcttctagcc aagcgaatca ataaggcaat tgctttttat cgggctcaaa
     4141 gccgtgctac attaaatccg cccatcttat tgatgtctgg cgggcaagga gcagacgaaa
     4201 aagtaccaga ggccattgcg atgaaacaat atgccatgga acaaggaatc cctgaaagag
     4261 acattcttgt cgaaaccaat tcgacaacca ctttggaaaa catgctctat tcaaaggaaa
     4321 tcatggatca gcaaatgaaa gggccatacc gcgcgatctt tagttccaac aattaccaca
     4381 tttttagagc cggtctttat gcgcggcaag ccaaattgaa agcaaatggt attggtgcaa
     4441 aaacagcttt ctactacttg cctaatgcgt ttttaagaga atacctcgcc atcttgatga
     4501 tgaacaaaaa aagacatatg atcatttgcg gattgctttt cgcaggctcc gcattcttat
     4561 cgctgattac tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt
     4621 ttttttcttt cattctctta actattggca aaaagagtat cccttttttg accgctactt
     4681 gctgagcaga ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa
     4741 agaagtatac tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg
     4801 gtgtatttgt cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag
     4861 aaacatggag caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg
     4921 tcacttctcc cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa
     4981 taaaatcata gacatgtgcc tgtccattaa atgattcttg aagtaacgga agactcaatc
     5041 cgagataacg ttgtgtttgc aaaatcaatg ctgctgccac aactacagct ccacctatcg
     5101 tatttcgaca aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg
     5161 aacggctgaa tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga
     5221 acagcaacat actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat
     5281 agctttctgt catgaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg
     5341 ttcggacttt cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc
     5401 caaatacaga actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt
     5461 tatccaatcg gaacaaacgt gccgtattat ctgctaacgc tccccccatt tggactgctg
     5521 ttccttcacg gccaacagat cccccaaata aatgggtagt tatggttcca aacagtgtaa
     5581 gtggaataag ccgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt
     5641 tgtttccacg actagaaagt ccgccgtgat acgcatagag ataagcaaaa agcgcaccac
     5701 taactggtag tagacaaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca
     5761 ggctatttaa gaaaaaagca gacaagctcc ccatgaatat accgagaatc gctgtgatca
     5821 ccagccactt cagcatatac actaaaatgc gtactggact cggtaattgt ttttccataa
     5881 aaaattcctc ctcaataaaa aaacgcctac taaagaaagg ggctgtcccc agactttagt
     5941 aggcgtcatt agctatcttt cgttagcatt taaaggcgaa caccatcacc tattcacttc
     6001 cattaaaaga tagcatattt ttctgtaaaa aacaataaaa ttatcgttct ttctttacac
     6061 gttcagcaaa ttcatagaaa ggagccaatt tcgttaactg ttgattacat tggtcactat
     6121 catgacaaat ataattcccc tttttcgtat acgtgccatc agaacctgct ttcgttgtag
     6181 aaagaaaaag cgaaacattc gatgttttct gacagattgc acagattccc ttatttatcg
     6241 ttggtgataa agtaccgcta atccctttta atttttcatc ttcgtaatag accatgaatt
     6301 ttttctgcgt acctggatca ttccagccga tgtacgtatg ttcttgcaag tcgatttcat
     6361 tccaagctgg ttgtttgagt tttttcactt ttcggaataa tttctcgatt tgtggtttgc
     6421 taggctgcat aaacggctga acgatttgct tcagctcctc caatgctctt tctgcttgcg
     6481 cttttgtcag ttttacgtct aaaactgtcg ttaaaaatgt atcgattctg gcagttcgtg
     6541 atctaatatg tctcgaatct tttcagctgc tagtgcctga actgtttgta ccgtttttgg
     6601 atcattgaca gatgagtacg catttaataa ctgttctact tctcttatta taaaaaaata
     6661 ttggtatggt tttattgttt gttccatgat tttaaagtcc tttcttctaa ccaaagtgca
     6721 tactttgtag aaaaaagtga tcttctgcaa agtatgtgtt acctgaagat cctggactct
     6781 tttaaataag atacgttttg catcttatca tcaccccctt taatgcttat tattctatgt
     6841 acatgattca ttcgataaat aaaagtaaac cgtatcttga acagatagtc aactgcaaac
     6901 agaaaaaagg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaatg aatggtgttc
     6961 aaaagcttgc atctgcggta ataagccgaa acttcacaaa aatttgagaa gtaattttcg
     7021 taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaat atggtctatt
     7081 attggtttta cctgttaaat cgaggattct ttcccaaagt aacgttgcca tctcttacgc
     7141 atacttgcag acatgggctg agccgcttct ttgactgcgc agtatttgtc cacgaatgtc
     7201 acaatatatc cttctttata cttaggcggt gcgatcgttg caccccacat gtgcttcaaa
     7261 atgatatctc gctcaagatc cgacaaatcg gtgatttttt ctgcattctt tacagcaatt
     7321 cttggatgga tatacgcatg tgtcccctcg tcaaatttcg tcgtacgcca atcatagtag
     7381 aacagatcat gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt
     7441 gcgagcagat aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca
     7501 tgctgtgtgt aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttgtacataa
     7561 gacatatatt cttcgtcttc acgccatttt tctgtcataa ttatcgattt gccacctttt
     7621 tgaatttcat tttcttctga aattgatcta agtataccac cagtgttcgg attattctag
     7681 tcgctctaga taaaatagct aaagcttaat agttccttaa tcataaagaa aaatgataaa
     7741 gaacgatccc tgctgcgact ccgacattca atgattccgc atttcctttc attgggatat
     7801 atacgttctg atcagtcgaa gacaagattt cctgacttac tccctgacct tcgtttccca
     7861 tgattatagc gaaatcctct gttttttcta ctttgtctaa tgcatgtgct tcttcattta
     7921 attctgtacc gtacaccgta aaccctttgc ctttcattac agggatcact tctgccaaat
     7981 ctttttgtaa cacaggcaaa tgataattgc ttccctgcat gcttcgcagc acctttgtac
     8041 tataaatatc tgccgttcct ttacctaata aaacaccagc cataccaaac gcatctgccg
     8101 tacggatcat cgttcccaca tttccaggat cctgtacatt atctagtaaa agccagcctc
     8161 ctgaaaaatc tggcgtatct tcagatgtta acgtcatcac tgctaagatc ccttgcggtg
     8221 taggtagatc tgacatagcg gtcatgacct catctgaaac tagaaaagta gaaatctctt
     8281 tgtttacagc cagccagtct ccccattctt tcatacctct ctgtgtcaca aaaagttctt
     8341 ttatttctgc atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt
     8401 ctgccttttc ttctctgtat ttctttttat gtagtttttt taattctttg attcttggat
     8461 tttttactga ttggatctct ttcacattcc tcacctcaac tgattatatc atggaatagg
     8521 tgcttgagct tgtttcatcc taaaaaaatc ggtatcattg atttataaaa caggaaagaa
     8581 aggtgacgaa catgcgcaaa gttaaaatga atgtccaagg acgtgtccag ggcgtgggat
     8641 ttcgctatat gaccaagatg gttgctgatc agttaggcgt gaccggaacg gtaaaaaacg
     8701 aagacgacgg ctcagtcaca atcgaagcaa tcggaaatga cgacatcatc caaaaattta
     8761 tcgaagaagt caagaagtct ccgagcccaa gtggacgagt gcagtatgtg gatgtccaag
     8821 aagatccgat gattgaggaa cgaaagaaat ttgatgtggt gggataaggt tgtttttgaa
     8881 gcgctttgcc tcgagtatta aggagaaaca ttttccaaat agcttctcat attttgaaat
     8941 gtaatgactt aataccgaga ggcagctgat aaaacaccgt caataaggtt gtgaaaaagc
     9001 tggtctgcat caagcattaa ggactggttg tgaaaaatag ctctccatat ttttcaacag
     9061 gctggactta atgccgtaga tgcaagcttt tgaacatcgt cgataaggtt gcgaaaaagc
     9121 tgatctgcat caagcattaa ggactggttg tgaaaaagtc gcttagtttt gagtattaag
     9181 gaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttaa taccaagaaa
     9241 ctgacttttg aacatcgtcg ataaggttgt ttttgaggca ctttgcctca agtattaaag
     9301 acaggtagta aaaaagctga tctataactt gcaataaatt tgcttaaccc atattttcca
     9361 gacagaacaa aaaagttttt agttttttaa ataagaaaga aacacttgga atcactcttt
     9421 tctttctaag tatttctttc ttgatttttt gtcttttttc aaaatttttc gctacgaaaa
     9481 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
     9541 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
     9601 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
     9661 gattcaaacg gaaaccctga cacttcagga atcgtttatc gagtactcgt ccatcctatg
     9721 ggccaagcga ttacatatct agttgagaat ttcaattggt cttacggctg ggcagttatt
     9781 gcaatgactg tgatcgttcg tatcatcatc ttgccactag gtatcagtca atcgaaaaaa
     9841 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcacaacaa
     9901 aagctaaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
     9961 gtatatcgcg aaaatggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    10021 caaatgccga tcttctctgc cttgtatttt acggctcgct acacagaagg tatccgtgaa
    10081 tcatcttttt acggcatcga tctaggctca ccaagtatgg tgcttgtggc catcgcaggg
    10141 ggcgcttatc tgcttcaagg atatatttca acaatcggta ttcctgaaga acagaaaaag
    10201 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    10261 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    10321 atcacaaacg ttataatgaa accgcgtttg aaagcacaag tggcagaaga gttgaaacaa
    10381 aacccgccaa aacaagtcgt tactccaaga aaagacgtga cagaatcagc agcaaagcca
    10441 gctgacaaca aacaagcaac aaaacaaatc aaacaaccaa aaaacagtac aaacaacaaa
    10501 ggccgcaacg caggaaggca gcagaagcgg aaataaaaat atatgacaaa aaactgtaga
    10561 caaataaaaa aatttctttg ttctacagtt tttttgttac aattaaagaa aacgttcgca
    10621 tttcgaggag gaatgtataa tgatgtccaa ataatcaatg tatagtcgaa tggaagaaga
    10681 caaaatttcg ctagatgcac ttgttcctaa aaatcattta gtccgtaaaa ttgacaaatt
    10741 attgtcattt gattttattt atctcattgt tgaatcaact tactcgacca ttggtcgccc
    10801 tagcgttgat cctgtcgtct tagtaaaatt agtattcatt caatatttat ttggaatttg
    10861 ttcgatgcgt cagaccatta aataagttga aacaaaccta gcttatcgtt ggtttcttgg
    10921 gcttagttta attgataaag ttcctcattt ttcaactttt ggtaaaaact atgcacggcg
    10981 tttcagagaa accgatttgt ttgaacagat atttatcatt attctcgaat aagcagttga
    11041 tgctagattt attcatgaag aaattttgta tatggattca actcatatta aagcgaatgc
    11101 gaacaaacgt atttttacaa gagatatggc acataaagaa gccattttat accaaaaaca
    11161 attagaagaa gaaatcaatg aggcaagaat tgccgaaggc aaacgtcctt ttggttcaat
    11221 cattcgtcag gaggtggtcg aaagaaaatt tagcatcgca gatccagaaa gtggttatta
    11281 tgtaaaaaca gaacgagaaa aacagtttgc ttattctgct cataccgttg gtgatgaaaa
    11341 tggttttgta ttagatgtca tgattacgcc tggaaatcta catgatagcc gaatgctcgt
    11401 gccacaaatc gaacgcgtta aatcacgtta tggtgtagct gctaatgctg cgtacaaaac
    11461 accttggaac gtcaagtatt taatcgaacg aaaactacga cccattctcc cttatatcag
    11521 tttcgcacaa ctactcgaga tggctataaa aaatatgtat ctaaatcttt tatttgtgaa
    11581 agttgtccat tattgaaaaa ttgtacagaa agccaaaaac accaaaaaga aatacatcga
    11641 catatttggg aagactactt agatgaagca gaacatttac gccatacggt gtacaatcgt
    11701 gaaaaatata aaaaaagaaa agaaacgatt gaacgcattt ttgcagacgc aaaggaaaaa
    11761 catggaatgc gctacaccaa gtatcgaggc ttggaaaaaa tcaggtgcat acaatgcttg
    11821 tttttgtcgc aatgaatctg aaaaaattag ctacttggca gtgggagcat atgtcgttat
    11881 atcttttatt atacaaaaat agacaaaagt atcagtctac actcttagta aagaggaaac
    11941 tgatgctttt gtctacagtc ttagagagtg ggacaatagt tttttcttct ttacgtcttt
    12001 tcctctccat gtattttcct aattttctta atttaacgcc atgagtgcca agccaatgtc
    12061 aatcttggct ccttgtttcc ttcataagtg gaaatccgtt tccgatagat cgaaccttct
    12121 ttttcctcta aaagtttttt tacattctgc tttgaaataa cgccatgtat tattcactaa
    12181 aatttgtcgg tttcgctcac tttttgcttt cgtacattga ctacgaacag gtcagcaccg
    12241 accactttca cattcgtaaa ttttgaagac acgtataaat ccacttttat cttttcttcg
    12301 actaaagcgt tgaccgcaaa agcgacatct gtttcagaaa tatattgttc catatctaat
    12361 ggtaaaattt tttggttgat ggtataattt ttaaacataa agcactcgct tcctttctga
    12421 ttgggtttgg tcactttaat cctacaggga tgagtgcttt ttgtgtacct taaaatcagt
    12481 aaatatccat ccgtgaaaac gggtggcttt ttaacagccc tagaagggct caccactcac
    12541 agccctatct ctctttaact atttaaatgg atctacatac tcttgtttac ttatactgtc
    12601 tctaattcga tcatctgctt cttgttctca aatatatatt tcaattgttt tttgatttaa
    12661 cccaaccgta ctcacgtagt atcctttggt ccaaaagctt ttattcccat acttatattt
    12721 caaatttgca tgtttttcat ggattaaggt tgcacttcgt ccttttaagt agcccataaa
    12781 actagaaata ctaatctttg gcggtattct tactaacata tgaatgtgat caggcattgc
    12841 atgagcttca atgatttcaa catctttcct ctcacacaat tttcttaata tctggccaat
    12901 acttactctt aactttccat aaatcacttt tcgtcgatac ttcggggtaa agactatgtg
    12961 atacttacaa tcccatctcg tatgtgctaa acttttatcg ctaaagctat ttcgtccacg
    13021 cgtagaaacg cgcgtttttt tgtttcgtac gctacgccaa cgaaactgac taaagtcaat
    13081 aaaaaaagtg gggcaataat cagatttttt tctgactatt gtcccactct ctttttatta
    13141 ctcttcatct tctactattc cactaattaa ttagttgaca gatacaatgc tttcacatcc
    13201 tgcacgaaca aactcgggct ctgaaccaat cacttgcgag ttgataaatt caatgaccat
    13261 aggaagatta atccgacata aagtttaatc tgttgtcctt ccattatcag tttagaaatg
    13321 atattagtag gtgtaccgcc taaaagatcg catagtacca caaaatcatt taacgaatct
    13381 atgacagtaa gagcttttgt ctgtatgttt cagtgccatc ttctggtaat aaaggtaacg
    13441 tgtagatatt ctcttgaggt cccataatca tttttgtact ttttttcaat tcctcacaaa
    13501 attttccgtg actaatcaat atcaattttc tactcatttt tggctctccc ttatttcgaa
    13561 atcacacaca atgcagataa agccacacac aagtaatacg ataaaaatcg ctcgagttgg
    13621 gtcatatttt tctttcctaa caaccaataa acacctcgac gatcccagcg agtaagattt
    13681 tagataatat catatcgata tagttttgca tattcaatgt cacatcgcca atcgttggta
    13741 ccataaaaat ttaatatcaa tcattgttgc aactaatgct cctaccatga acactcttaa
    13801 taaagtcgct acgtccgtta atacagttaa gcgagattac actagatgat ctgttcctgc
    13861 caaggcaaga gccagaagcg gttgcctgcc catttgcctt tggtgtgtcg gagctgtccg
    13921 ataaagttca ccgcccgatc cgctctggct ttgtcgtagt gacattccga aagcatgaat
    13981 cggcttggtg tgtattcctt taatttggga tagccctttg gtctggtttc tgccatcagc
    14041 taccacctcc caacagagcc tccatcgcat cttctgctcc gacaccaccg ccatcaccgg
    14101 caatgatacg gcttctggac gaaggcgtca gaccgaactg ctcggaaaat cggttcataa
    14161 ttttcagata ggtctgggca ataaacacct gtggtacctg ctgccaatag ccggataggg
    14221 ttttcacgat gataccgtgc tgggtaatga attcctcggc ttccttccag cgggcgtagg
    14281 cttggcacta accggcaaag gcagccatat ccacatctgt caagattccg atggcctcca
    14341 tctgctttgc cagacgcttc cattccttct ttgcctctgg ttccagccac ttcggacagg
    14401 tcggtgcctt cttttccggc gttgactctt ttgcattgag tgggcgattg cccggatttc
    14461 cctccagctt cttcatggct gtcggggttg attttcttcc tctggttgcc acagtcgtca
    14521 cctcccttca atgtatttct gccagtagac agagaacaga gccaagtcga aacctgactc
    14581 tcttctctat ctgctaactt gtatttcagt ccactcttct gatgaatcgc acccgcagga
    14641 ttttcaagat gccgcaggca aattccaaga agtttctgac cgcatcataa ccatcgtagc
    14701 cgtgtagcca catccttcca cctcgccgcc gtcctcgtcg ctgatataaa tgattctgta
    14761 ttcgctcatc tgttgttttc tccagtcttt tgtttttttg tagtacatat atcactctaa
    14821 aagtgattat tatcaagtcg tttgaaagcc ataatgtaca caatcattcg actggttttt
    14881 ggttcataat tgaccgccaa agtgagcaaa agaaagggac ctctgtctgt ttcagaagtc
    14941 cctttcggta tttggttctt agtggttcag gctgtattct caaacctcat actcatcttc
    15001 gaggtctgcc tctgcaatga tctggccgat gctgtcgtaa cgctggacct gcatctggat
    15061 ggcatccttg tctgctccct cgtccatcat cttcagcagc ttgtctgatt cctttttgta
    15121 ggcccagaaa aggatctcct gaaggctggt ctcctgcttt ttcttgcgaa gggcgacctt
    15181 cttctcttcc accgcctcgt tcaacttggt gaactctgcc caagcaagga taccgtctcg
    15241 cttgattgcg atctccacat ccttcagctc cgggatggtc tttgcaccct tgatctcctt
    15301 caaatatttc tttgcctttt cgctcattgc cattagcgtt tcctccttgt ttttgggatt
    15361 ttcccctttg gttgtgtgta tattgccata gtctctcgac tatatcaagt caatccacag
    15421 gcatatacta cacaatcatt tggagctgta tttgtataca ttatgccgat ttatgagaga
    15481 agaaaaggct ccagccgttc gactggaacc ttgggggggt cggtttctta ggcggcgtgg
    15541 cggtgtagac cttgaggtag ctgatgttct tccagacgtc cgtgcccttc agtctgacca
    15601 tgccgtccag ctctcggtcg agggtgaact tgcggaaaag cttgatgcgg ttgaggctgt
    15661 ttgctagctc cttgccgttc ttggcatcca gaactgcgtc ctcgatctcc gcaatactaa
    15721 tttcctgtct aaaccaaagg ttgctcaagg cttcgggaat gccgtttgcg gtctgcaggg
    15781 ggttgaaagt ttccaataca gcaggggtcg aaaccacctg tccgagctgg aattttgcgt
    15841 tccctaaaat catctgcata atttcttcca tgtgaatcat ccatttctgc cgttgtggta
    15901 ttccctttgg cagtacagta ctatatatca ctctgaatcg tacatttatc aagaagcgga
    15961 tttttgtgga atcaccaatt cgatataata gtaattgcat gaaaaatcta agcactggat
    16021 tggtaggtga tgattatacg tgacgatcac atttacacct gtgattcctg ccactacagc
    16081 ttccctgccg acgaacagcc agagcgttgt cctgactgcg aaaagacagc aactcggctg
    16141 gataccgaaa tcgaaactga agattactat cgtgttcgtg ctgaaatcaa agctgagatt
    16201 aaagctttga atgcgggtta acgacaggta ctgaccggcg gctcaacacc gccggctttt
    16261 tattaccaca tcttgcggaa ttcgctggga cgaacacctt ccaccttgaa aaaagttctg
    16321 gaaaaatagt ttgcatctgt tatgccaatt tttgttgcaa tctcttccat acttagattt
    16381 gtaaagcgta gcaagtgctt ggcctgtgtg attcgtttct gattcagata accgacaaca
    16441 gttgtaccgt aagtttcacg aaaaatctta gctaagtact gtttattgat aaaaaactct
    16501 gcactcaact gatccagcgt aatcttctcc gtgtaatggt catccagata ttgttttatg
    16561 ttctgcaatt ccattttttt tgtagagaaa ttcggcactt tgtcaggatt ccaagaatct
    16621 tccatcaaat gcatcagcaa ttcactgagt agaacattga ttttcatatc ccggacatac
    16681 tcctgtccct ctgccaccat atgaaggctc ctcagcaagt cagcatactt atctgttttt
    16741 gatgttttaa agaccggttg accacctcgt tcaaggtatt ttttgtagac ttccgtcata
    16801 ccaatgccat taaaatggca ccaccgcaaa gtccacaaat catcttctga tgactcatgg
    16861 acatacggct tcaaacagtc aataaacacc atatctccta cttgaagcgt atatttctgc
    16921 cccttatact ccaatgtgcc tgaaccaact tctaccagga aacaaaggta agatgacaat
    16981 cctgtacgcc tagatgtatg tgccttcaga gcagtcagct gtccaatttc ctgcaaatac
    17041 aaaagagagg atcttgcaaa gaacgatgcc gtgtacagca cacgatttga cttcaccgat
    17101 ttcaaagcgt tagaaaacag ttcctccatt acaagatttc tcctttcttt tcttactcga
    17161 acatttccgc cagttcagca gccataatag cttccatagc ttcggcggct tccttgttct
    17221 ctgcgctgac gctgatatag gtcttcagct tcggctcagt accagaagga cgaaccacaa
    17281 cagagcagtt atcttccagc ataaacttca aaacatcaga cttcggcaga ccattcaggc
    17341 ccttactgta gtctaaagtt tcaataacct tcttaccacc aattatatcg agacccttgt
    17401 ggaattcaac cataatttcc tgcatcttgg taaaacctgc cgcaccgtca aactcgaagg
    17461 aatgcagggt gttcaaacaa tagccatact ttgtataaat ctcgttcagc ttatccagca
    17521 ggctgatacc ctgagtcttg tagtaagaga acatttcaca gattagataa gcagcgttaa
    17581 caccgtcctt gtcacggaca tagctaccgg acagatagcc gtaagattcc tcaaagccga
    17641 agatatagct gtcaacctta ccagcctttt ccaacatacc aatctgctca ccgataaact
    17701 taaagccggt cagcacatcg atggtacgaa caccatagtt ggatgcgata cgttcaccca
    17761 aatccatggt gacgatggtc ttgaccatca cagggtcagc aggcattttt ccatgcttaa
    17821 ttctctgaga acagatgtag tccagaagta gcagaccagt ctcattacca gacaacagaa
    17881 catagtcacc atgtgcgctc ttaactgcga taccaacacg gtcgcagtca gggtcagtgg
    17941 ccaacagcag atccgcattg tacttcttgg catactccat acccagagac atagcttcct
    18001 taatttcagg gttcggataa ggacaagttg ggaaattacc gtccggcaga cgctgttctt
    18061 ccacaacggt cacattgctg tatcccatct ctgccagggt gcgggtaaca ggcaccagac
    18121 cggtaccatt cagaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca
    18181 ggacggactg ccccttcact tcttcgatga aagcagtcag aacttccgac tgaatggatg
    18241 caatcttaga agcatcgcca tccatcttta catcagcaaa gatgtccagc ttttcgattt
    18301 ctgccagaat tgcagtagca gcctcggtag taatctgaca gccgtctgca ccgtatacct
    18361 tgtagccgtt atatttagaa gggttatgag atgccgtaat cataacaccg gcatctgcct
    18421 tcagataacg agtcgcaaaa gatactgtag gaacaggaag cagttctggc cacaagtgca
    18481 cctgaatacc atttgcagca aagatgtctg cggcagtctt tgcaaacaca tcagatttga
    18541 tacgggaatc atagccaacc accacggaag cggcttcata gttcttattc agatagtctg
    18601 ccagaccttg gcttgcctta cctacggtgt gtacgttcat gcgattagtg cctgcaccga
    18661 tggtaccacg cagaccacca gtaccgaaag acaaattttt atagaaagag tcctcaatgt
    18721 ccttctcaga ataggaacgc agttcttcta taatatctgc attggcatga ttcagccaac
    18781 gctcatattc tactttataa ttcatattat tatcctctca catccagaaa ctgaatcgac
    18841 ccgtgaatgc tgatttcagt agaatcggcc ggcacaaaaa ggcagtcccc cttatagatg
    18901 tccaacgatt cattatcaaa tcgaacggta ccacagccat tgacacacag caacacacgg
    18961 aagctgattg aatccgcacg atagtgtacc gtctgtcttc tctcagtgtt gacaatcata
    19021 cgagagacct cgaaatgctt gcatctgcaa agcaattccg cagctacacc agcacgatat
    19081 tttagaacac gaagcggctg tttcggttct gacaaccctt tcaagttcgc tacttccagc
    19141 gctttgtcta catgaagttc tctcttttta ccatttttgt caacacggtc ataatcgtag
    19201 agacgataag tcagattgga attttcctga atttctgcaa ttagtgcacc cgcaccaatc
    19261 gcatgaatcg ttcccgcctc aataaagaac acatcattct ttttgaccgg aaccttctga
    19321 agataacgct caacagttcc ctgagcaatc gcttcacgga tcacagcttc ttctgttatt
    19381 ttctgcagcc catagattaa gctggcatcc agtacatacc acatctctgt ctttccaagc
    19441 tgcccgtttt ctttttcaat tgcatattca tctgtgggat gtacctgaac agacaaatcc
    19501 tttttcgcat caatgaattt gatcaggatc ggcaattctc ctttggtctg cggatgcgtt
    19561 cccagaaact ctgggtgttc ttgcaacacc tccgtcaagg tcatcccctg atactctgac
    19621 cagacacaac aaagctcggt ccatccgggt gcgtagagca ttccaagttt ccgcaagagg
    19681 agacatctca attccttttg caaattcatc attcaggcgg ttccccccca cagataatcc
    19741 tttgcggaag gcttcaataa aaacggtttc tgtataacga gccctcctcc gttttttaat
    19801 actctaactc aaatttctgt ttatctttaa cattgatatc cttgccaagc tgtacttcaa
    19861 tcagcttcag ctcagtatct gccataatgg tatgccgaca gccagcactc atggtgatca
    19921 catcgccagc cttaacaacc tgctcatatc catccacgat ggtcttacca gtaccggcca
    19981 gaaccaccca cacctcgtca cggttcttgt ggctgtgata attcatggag tgactagcat
    20041 tcagagtaac cttaatggtc atgctctctg cttctacatc cataacctta taactacccc
    20101 aagacttctc tgcgaacatg atctgctgct cgaacttgtc aacgaaaggc ttaatatagc
    20161 tggactgttc cttatcggaa accagaatac cttcccgaga tgcacagatg accacatcat
    20221 gcagacccat agccaacaca ggaacatcca gttcgttcag gatgtgtacg ccatcgcaat
    20281 tctcattcat aacaccttta ccgataatgg attcctccat accttcggtc agagtattcc
    20341 aagtccccag atccttccac ataccagcaa aacgctgtac ctgaatcttg tcctcatgct
    20401 caacaacggc atagtcgaag gaaatcttag tcagagtatc gtatttgttg aacagatcct
    20461 gataatctac aaagtcaatc agctgatgtg cacgctccat gacatacttc agcttgtaga
    20521 caaacacacc accgttccac agtgcaccct gtgcgatata ttcctttgcc acagcctcag
    20581 aaggtttttc cttgaaggta tttacgaaag cagtctgctc tgcgctctca ggaatgatgt
    20641 agccgtactt ctcggaagga taagtcggtt caatacccat gagcaccaga ttagcttcgc
    20701 ctttgtcagc ctgatcggac agagatttca gggcctcaaa atagtcatct tctacgtaag
    20761 ggtcaaccgg gcaaacaact acggactctt ctggatcaat gcccatcaca tctaccagat
    20821 aagcggtagc caatgcgatt gccgggaagg tatcgcggcg acaaggctct acagatacac
    20881 ccacatcctc accaagttgg ttatggatag cagaaacctg tgtcttagag gttgcaatcg
    20941 taacagttgc gtcgttatct accttcttaa tctggcggta gacacgctga accatggatt
    21001 catatccatc ttcagttttg aaaatcttaa tgaactgctt ggaacggatg tcattagaca
    21061 gcggccaaag gcgcttacca gaaccgccag acagtaaaac aatattcata atgatctctc
    21121 ctttttataa gaaagaggct gctgcaatcc tcaaaaatca cagcaacctc ggtaaattag
    21181 cgttcagcac gcatcgggtt attcaggaag tcctcgtagg acagacggat gccatcttcc
    21241 aactcagtct tatatgtcca tcccagcttg gttgccttgg aaacatccag cagcttacga
    21301 ggtgtaccgt tcggcttgct ggtatcccac agaatctcgc cttcgtaacc aataaccttt
    21361 gctaccatct cggtcagttc cttgatagac agttccttgc cagtacctgc attaacagtc
    21421 tcgtcaccgc tatagttatt catcaggaac acacacaggt ttgccagatc gtcaacatat
    21481 aggaattcgc gcagaggaga accatcaccc cagcaggtaa cagtaggcag acctgcttcc
    21541 ttagcctcat ggaagcgacg aatcaaagcg gggagcacat gactgtgagt aggatgatag
    21601 ttgtcgttag gtccatacag gttagtaggc ataacagaga tatagtcagt accgtactgc
    21661 ttgtttagaa actcacagta cttcaggcca gaaatctttg ccagtgcata agcctcgttg
    21721 gtcttttcca gctcacttgt cagcagacag ctttccggca tcggctgcgg tgccatacgc
    21781 ggatagatac aggaagaacc gaggaactgt aacttcttac agccattctc ccatgcggag
    21841 ttgatgacgt tcatttccag aatcatgttt tcatacatga agtctgccag agcgttctgg
    21901 tttgcgataa taccgccaac ctttgcagca gcgagaaata cataatccgg cttttcctgt
    21961 gcgaaaaatg cttcaacagc gtcctgacgg cacaggtcaa gctccttatg ggtgcgggtg
    22021 ataatattgt tgtagtcctg acggttcagc tcgcgcacga ttgcggaacc agccatgcca
    22081 cgatgaccgg ctacgtagat ttttgcgtct ttttccatca taataatgct tgctcctttc
    22141 taaatttaga gcatctctca ttgcatgaga gaaatcaatt tgtctgcgat ttcgctcgca
    22201 gcatcataaa atgtatcaaa atttgaggtg tctagctgtt tgaggtcctc aatcacccgc
    22261 tctacgcggt ggaggttttc cggtgtgacg gaaattgcca gacccagttt ttgcaattta
    22321 caaatagttg ttctatcttc caaaactgta tcgcgggcga acagtgccat cggacgctgt
    22381 gcgagaatac actccgcaac agttccccat ccagcctttg taataacgta atctgccgcc
    22441 gctatatagt cctgtgtatt gggggtgctg ttagaaataa cggttacgtt ttctcccaca
    22501 agcggaacac ctagcgttgt aatgaaatca tacggcgcgt gactgacatc aatcggctgt
    22561 ttgaaccgcg cggacatacc gagtgcgaca aatacaggcg gtttttcatg ctgtgattta
    22621 atgcgttgca cttcgtcgtt atgaatcgga cgcgccacaa cggaagtcgg tgttttttcg
    22681 ctgttttgga gaaattccaa catttcttcg ttatttagcg cataaagcat ggtgtgctga
    22741 attttaccgt aacgcttggc atattctttc caaatatgtt cgggtaaaaa ttcgcgatac
    22801 agctctgtcc aagtgaagtt tcctacatac aggaaaggta ctcctgccat atcgcaggca
    22861 tccattgccc agattggcat atcgcaaagc actgcgctga cagcttctcg cttgagccat
    22921 tcggcttctg tctttgccaa agaaggaacc tttgccaaaa aataaacaca gatctcggtc
    22981 agcttacccg tgtccaccag tagggtgccc tcacggttaa tcagaccgat atctgtgttt
    23041 attggacgat agcgcacgcg gtctatcagc tctttgggca gttcctgctc caaattgcgc
    23101 tttgcaaaat ccagatgatt tgcgccgcaa accagtgtaa tcttcgcttc gcatcggcag
    23161 agtgttgcca taataatggg cagattccgc gcgatatgtc cgaagccgtg actggaaaga
    23221 tagaaacaga tatgtttatt caatgtcagc ttacttgact gcgttcttca ttgcagcttc
    23281 gcgctttgcc aattcacggt catgctttgc catgatgtta accagttcct cgtaagaggt
    23341 cttctgcgga ttccaaccga gaacggtctt tgccttagtc gggtcgcccc acaggttgtc
    23401 aacgtcagtc ggacggaacc actgtggatt tacacaaacg agcatcttgc cggtttcaac
    23461 atcgtagccc ttttcatcaa tgccagtgcc ttcccaacga atggtcatgc catttgctgc
    23521 gaatgccttc tcggtgaagt cacgaacagt gtgctgctcg ccggtagcga tcacgaagtc
    23581 ctcgggagtc tcatgctgga gaatcatcca catgcactca acatagtcct ttgcatagcc
    23641 ccagtcacgc agggagtcca tgttgcccag ttccagatgg tcctgcaggc cttctgcaat
    23701 gcggccggca gcgagggtga tcttacgggt gacgaaattc tcaccgcgac gttcggattc
    23761 atggttgaac agaataccgt tgacagcgaa catgccataa gcttcacgat attccttagt
    23821 gatccagaag ccatactgct ttgcaacagc ataagggctg taaggatgaa acggagtggt
    23881 ttcacgctga ggaacttctt caaccttgcc atacagctca gaagtagatg cctgataaat
    23941 cttagtcttc ttcgtcaggc ccagaatacg gcaagcttcc agaatacgca taacgcccaa
    24001 agcatcaaca tcgccggagt actcaggaac atcaaaagaa acctgaacat ggctctgtgc
    24061 agcgaggtta tagatttcat caggctgaac aatgctgatg atacgaatca gagaagatga
    24121 gtcggacagg tcaccgtcat gaagggtgat cttgcccatc aaatggtcaa tgcgagcggt
    24181 attggaaata gaagcacggc gagtgatacc gtgaacttcg tagcccttct ctagcaggaa
    24241 atctgccaga taggaaccgt cctgaccagt aataccagta atcagcgctt ttttcatgat
    24301 acattatcct ttcctatgta agtgataagg ccatataaat ggctcgtaat ttctaatact
    24361 tttcaagaat acacgataat tttcgatatt tcatagaaca atctacgcac gcattagcac
    24421 aatattagtt tttcgtg
//
LOCUS       DBGZHO010000038        24283 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.038, whole genome shotgun sequence.
ACCESSION   DBGZHO010000038 DBGZHO010000000
VERSION     DBGZHO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.038"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(48..1343)
                     /gene="purB"
                     /locus_tag="ACN3HL_001750"
     CDS             complement(48..1343)
                     /gene="purB"
                     /locus_tag="ACN3HL_001750"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HHC8006609.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1356..2480)
                     /gene="purK"
                     /locus_tag="ACN3HL_001751"
     CDS             complement(1356..2480)
                     /gene="purK"
                     /locus_tag="ACN3HL_001751"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HHC8006610.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2473..2961)
                     /gene="purE"
                     /locus_tag="ACN3HL_001752"
     CDS             complement(2473..2961)
                     /gene="purE"
                     /locus_tag="ACN3HL_001752"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HHC8006611.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3377..4684)
                     /locus_tag="ACN3HL_001753"
     CDS             complement(3377..4684)
                     /locus_tag="ACN3HL_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HHC8006612.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4687..5268)
                     /locus_tag="ACN3HL_001754"
     CDS             complement(4687..5268)
                     /locus_tag="ACN3HL_001754"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HHC8006613.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5384..5481)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5840..7132)
                     /locus_tag="ACN3HL_001755"
     CDS             complement(5840..7132)
                     /locus_tag="ACN3HL_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8006614.1"
                     /translation="MKKKYVQVGLGGRARFFYETIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7129..7752)
                     /locus_tag="ACN3HL_001756"
     CDS             complement(7129..7752)
                     /locus_tag="ACN3HL_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006615.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7755..8591)
                     /locus_tag="ACN3HL_001757"
     CDS             complement(7755..8591)
                     /locus_tag="ACN3HL_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006616.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8608..9495)
                     /locus_tag="ACN3HL_001758"
     CDS             complement(8608..9495)
                     /locus_tag="ACN3HL_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8006617.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9511..10794)
                     /locus_tag="ACN3HL_001759"
     CDS             complement(9511..10794)
                     /locus_tag="ACN3HL_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006618.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDCLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11477..12160)
                     /locus_tag="ACN3HL_001760"
     CDS             complement(11477..12160)
                     /locus_tag="ACN3HL_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HHC8006619.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12178..12795)
                     /locus_tag="ACN3HL_001761"
     CDS             complement(12178..12795)
                     /locus_tag="ACN3HL_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HHC8006620.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12805..13629)
                     /locus_tag="ACN3HL_001762"
     CDS             complement(12805..13629)
                     /locus_tag="ACN3HL_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HHC8006621.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13622..14182)
                     /locus_tag="ACN3HL_001763"
     CDS             complement(13622..14182)
                     /locus_tag="ACN3HL_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006622.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14356..15312
                     /locus_tag="ACN3HL_001764"
     CDS             14356..15312
                     /locus_tag="ACN3HL_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HHC8006623.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15617..16573)
                     /locus_tag="ACN3HL_001765"
     CDS             complement(15617..16573)
                     /locus_tag="ACN3HL_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HHC8006624.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16677..17279
                     /locus_tag="ACN3HL_001766"
     CDS             16677..17279
                     /locus_tag="ACN3HL_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HHC8006625.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17367..18866)
                     /locus_tag="ACN3HL_001767"
     CDS             complement(17367..18866)
                     /locus_tag="ACN3HL_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HHC8006626.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18882..19406)
                     /locus_tag="ACN3HL_001768"
     CDS             complement(18882..19406)
                     /locus_tag="ACN3HL_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HHC8006627.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19704..20453
                     /locus_tag="ACN3HL_001769"
     CDS             19704..20453
                     /locus_tag="ACN3HL_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HHC8006628.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20444..21229
                     /locus_tag="ACN3HL_001770"
     CDS             20444..21229
                     /locus_tag="ACN3HL_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006629.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21198..21914
                     /locus_tag="ACN3HL_001771"
     CDS             21198..21914
                     /locus_tag="ACN3HL_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8006630.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22016..23035)
                     /locus_tag="ACN3HL_001772"
     CDS             complement(22016..23035)
                     /locus_tag="ACN3HL_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HHC8006631.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23054..24055)
                     /locus_tag="ACN3HL_001773"
     CDS             complement(23054..24055)
                     /locus_tag="ACN3HL_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HHC8006632.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         7202 a         5226 c         4226 g         7629 t
ORIGIN      
        1 ttatttttgc tattctattt taattgaatt ttgcaactca ctcttcttta ttccaaacct
       61 actcgtttga atatcacgtc aacgtttttc aaatgatgat gataatcaaa ggcatcgtct
      121 atttcttctt tagataatac cgatgtgatg gttggatctt cttctaacag cgggcggaac
      181 tgcacttggt tgtcccaagc gtacgcagtt tttggctgaa caagatcata agcttcttct
      241 cttgtcattc ccttatcgat caatttcagc ataacgcgct ggctataaat caaaccaaat
      301 gttgcagaca tattccgctt catgttttca ggaaagaccg ttagattttt aacgatattg
      361 ccaaaacgat ttaacatgta attcaataaa atcgtggtat caggcaagat gattcgttct
      421 gctgaagaat gagaaatatc tctttcatgc cataatgtga cattttcata ggcagtgacc
      481 atgtgtccgc gcaccactct ggctagacca gccatatttt ctgaaccgat cggattcctt
      541 ttgtgcggca tagcagaaga acctttttga cctttcgcaa aaaattcttc tacttcacgt
      601 gtttcggatt tttgcaatcc gcgtatctct gttgcaaaac gttcaatact tgtagcaata
      661 agcgccatcg ctgagaaata ttcagcatgt agatcccgag ggagaacttg agtagagatt
      721 tcttgtggac ggatccccaa ttgtttacat acatactctt caataaatgg cgggatattt
      781 gcgaacgttc ccactgctcc tgagattttt cctgcttcta ctccttttgc cgcatgttca
      841 aatcgttcga tgttccgttt catttctgaa taccatgtgg caagtttcaa tccaaaagta
      901 gttggttcag catggacacc gtgtgtccga cccatcatca ctgtatattt gtgttctttt
      961 gctttttcgc caatgatttc cgtaaaacgt ttcaagtctt cccgtaaaat atcatttgct
     1021 tgcttgatga gatagccata agcagtatct acgacatccg tacttgttag accataatgg
     1081 acccattttc tttcttctcc caatgtttca gaaaccgctc gtgtaaacgc aacgacatca
     1141 tggcgtgtta atttttcgat ttccaagatc cgatcgatat caaatgatgc atgctcacga
     1201 atttttttca catcttcttg cgggatttca ccaagttctg cccaagcttc atctgctaaa
     1261 atctcgactt cgagccacgc acggtatttg ttctcttccg tccagatatt ccccatttca
     1321 gggcgtgtat aacgttctaa catgtttttt ctcctctaat cccaaatatt cgtttgtttg
     1381 atttcttcca gcgtttgctg gatgtcttct gtcaagatag tgatatgtcc catcttgcga
     1441 cctttttttg cttgtttttt tccatagaaa tggaattgcc agtctggctt attctcaatc
     1501 aagcgatagc tttccagcag ttgttctccc aaaacattga ccattactgc attgcttatc
     1561 aaacgtactt tttctcctaa tggccaacca caaatacctc gaatatgggc atcgaactga
     1621 ctcatagaac aagcttcaat agaataatgt ccagaattgt gaggacgagg agctaattca
     1681 ttcacatata gcccgcctgt ttttgttaaa aacatttcta cccctaaaac acctgaaagg
     1741 ctcactgctt ctgcaatcac acgggcaata cgctcagcct cctcgatcac atcctgatca
     1801 atcgcggctg gagcaatcgt ttcatgaaga atattgttgt ggtggatgtt ttccacgacc
     1861 ggaaaagtcg tgaaatctcc ttgaccattt cctgccacca tgatcgaaat ctctttttca
     1921 aacgggatcc atgcttctaa aacacaggtt ccttctctta aaaggtccat ggcaggagct
     1981 agatccgccc gacttttcaa aacatactgc cccttgccat catagccgcc tcgagtggtt
     2041 ttcaaaacac aaggatagcc gatcccgtca atcgcatctt ggatatccgt cggactgacg
     2101 atcgttgcat aaggagcaat cacgatgtta ttcgtttcca aaaaagattt ttctaacagg
     2161 cggtcttgcg taatcgcaag caagtctgtc ccttgaggaa taaatgacat gggtaaaatc
     2221 gcatttaacg cctctacact gacgttttcg aattcatagg taatgacatc tgttcttctg
     2281 gcaagctctt tcagcgcaaa ggtgtcatca tagacacttt caatgtgcca atctgcaact
     2341 tgtgcggctg gacaatcgct cacaggatcc agcacaccta ctttaaagcc catttctttt
     2401 gcactaatcg ccatcatacg acctaattga ccgccaccga cgatcccgat cgttgaacca
     2461 ggcaacaaag gtttaaccaa gttgatcact actttctata acagttttag ccaacattga
     2521 acgtctttca gccaatttag cctccaattc taaatcatac atggaaagca tctgtatcgc
     2581 aagtagtcca gcattaattg ctcccgcttt tccgattgct gtagtagcta caggtactcc
     2641 tccaggcatt tggacaatcg aaagaagcga atccaaacca tttaatgttc gtgattggac
     2701 cggtacaccg ataaccggca aagttgtttt tgatgcgacc atacccggca gatgcgcggc
     2761 tccccctgct cctgcaataa tgattttgat tccttttttt cgagcgtttt gtgcatattc
     2821 aaacatcaaa tctggggttc gatgagcaga aacgaccttt ttttcataag acacaccgaa
     2881 ttcatccaat atttgacatg cttctttcat tgtttcccaa tctgaagtac tccccataat
     2941 cacagagatt tttgctgtca ttgtttttcc tcccagtttt tctacattca tattttaaca
     3001 atcacttttt ttgatgtcaa agaaatttcg aatgttaaca aagaaaaaca ttttattgtt
     3061 cgtgtttatt aaagataaaa aaaaggaatg tgacaaaagt taggtcacat tcctttttat
     3121 ggataaacgg tgttctcctg ccaactcctc ggtcacaagg aacaatattc aacaaacatg
     3181 agaagctttt ttttgaaatt gttccttgtg actcggagat gaacggcagg ctcacgacct
     3241 cttccttcaa cggtgttcaa tcagctgacc ctcggtatta gctcaaacaa acggcaaaat
     3301 acgaggaact atttttccgt ttgtttctct aacaatcagg tcaaaacgct gatttcacaa
     3361 cctttctttt gctctattac ttcttgaagg cttcttccaa tatttcttca tcttttttca
     3421 atccattaaa gatcaaattc aatatgatag ccgtaatgct actcattacg atgccatttc
     3481 cagtgaacat ttgcaatgtt tgcggcattt gactgaataa tgtcggcgta acattgaaac
     3541 ccagcccaaa tccaacagaa acagcaacaa tcaatagatt tttatcattg ctgaaatcaa
     3601 cttccaacag catacggatt ccttggactg ccaccatccc gaacatgact aacattcctc
     3661 caccaagtac cggctcaggg atgatttgtg ctaacgcacc gattttaggg aataatccta
     3721 aaacaatcaa gaagaatgca gagaaataga tgggttttct tgttttgatt cccgaaagtt
     3781 gaaccaatcc gacattttga gaaaagccag tataagggaa tgtattgaaa ataccgccta
     3841 agataacggc aagtccttct gcacgatatc cctttttcaa ttcttcttct ccaacatttt
     3901 tcccagtaat gtcaccaagt gcaaaatata cacctgttga ttctaccatg ctgaccatgg
     3961 aaatgatgat cattagtaaa atcgaccata cgtcgaaagt tggtttacca aaataaaagg
     4021 gttgtggaac atggaacaac ggcgcatctc caatcgcgct cagatcaatc attcccatga
     4081 aagcagctaa gatgcttcct ccgactaaac caatcaatac cgcgattgaa cgaatgaacc
     4141 cttttgccag catttgcacg cctacaatta ggagaatcgt cacaaatgca agtagcagat
     4201 ttgttttgtc accaaaatca gctgctgttg cattacctcc acccattttc tcgattgcta
     4261 caggaatcaa agtcaaacca ataacggtga taaccgttcc tgttactata ggagggaata
     4321 gttttttaat tttagaaaag acaccagaaa ctaacacaac aaagatccca gaagcgataa
     4381 tagatccgta gatagctcct actccttcat tggttccgat caagatcagt ggagctactg
     4441 cttggatcgc acatcctaaa acgacaggca agccaattcc gaaaaatcgg ttaactgtca
     4501 attgcaataa tgtcgctaat ccacacataa agatatcaat tgaaatcaaa taagtcatct
     4561 gttcttgatt aaagcctagt cctgtaccga tcaaaagagg caccgctact gctcctgcat
     4621 acatcgctag cagatgctgc agccctaaaa ccgcagcttt tccattttgt gtttcttttt
     4681 ccacgattat gcgtcctcct caagaaactc aacttgtcca ttcgtcaagg aagcaatacg
     4741 cgcaagagaa acgactctca atcccatttc ttcaagtaac tgacgtccat cttggaaaga
     4801 cttttcgatg acgatcccga ttccttctac ttgcgctcca gcttgctggc ataattcgat
     4861 caatcctttt gccgcttgtc cgtttgccaa gaaatcgtcg ataatcaata ctttgtcttc
     4921 tgaagataaa aatttacgag aaatagaaat cgtacttgtc acttgtttcg taaaagaata
     4981 aacagaagct gtcaataatt cttcatccat cgtcaaactt tttgcttttc tagcgaagat
     5041 cattggaaca tctaattctc ttgcagcaaa taaagctggt gcgatcccag aagcttcaat
     5101 ggtcacaact ttcgtgattc cttgttcttt aaatacttct gcaaaccgtt ttcccatttg
     5161 ttccatcaat acagggtcta cttggtgagt gacgaagctg tcgactttta atacgccctc
     5221 gcctaatata cgtccgtctt tttgaatacg ttcaactaat tctttcactt tatttgctcc
     5281 tttatcattt attaataccg aaataaccgc ttttgtgcaa aaacctacta tgtttctgtt
     5341 aaagaaaaac accctccact ttatcataag aaaagaaggg tgaaatagcc aatcttttac
     5401 ttatagtcca gcatttacgg tactggctag aaactgtcat ccatattatg acgatatata
     5461 agtaggtatg taaaactaat aatagtgtaa attcattttc ttgcaactgt tttgcacgtg
     5521 aaggcagttt gccatatttg aataaaaaat gttgtttcaa atattgaaaa cagtctaaca
     5581 ctactttctg aaactgacaa cgtggtttac ttattttttt gtaaaatcta atgattttta
     5641 atgcattatt cctttttgtt cgggtttaaa tagttatttt tattttctcc tatctaaaaa
     5701 agcagcccac ataaaaagaa ggcatgacaa aaagcatgtc atagcccctt tttccgaata
     5761 aatagtgttc aaaagacagc ctatcggcaa taaggcaaga ttttataaac tacgggaagt
     5821 aatttccgta aatctattct tattctttta agctgacaag ctcgtcaatc actactgctt
     5881 ttcctgaagc aatagaatga tttgctgcga ttcctgtcaa aatcgacaaa ataccatcta
     5941 cgtgagttgc tgcccgattc cacggatctt cttctttttc ttcaccaaat agatcatcta
     6001 ataaacgcgg atctcctccg ccatgtccgc ccgcttcttg ttcgacgatt acctcatatg
     6061 gctcaccgaa catcggatag acatggatgg actgaagaac ggctgctcct tcatcctttt
     6121 tatctccacc tgcattgatg taagactttt cgatcacttt catttcgatc cgtcctttgc
     6181 tgccattgaa agaaacattg aatccttccc acggcatata cgcgtttagc gaatacgtca
     6241 aaatcgcacc agtttcatat ttgaccgtta cgcctagtgt atcttcaata gagatatcat
     6301 cggaaaatac actgcggtca cgaatatatc cactgtcttt ttctgcttct aaatacattt
     6361 ctcgcaattc ctcattggct gacaggtcta tagcaaatgg atcagcttta gctagttcgc
     6421 ttccatagca tcgactgtaa aatatttcta ctccgcgttt ctccgcatta tgcatcccat
     6481 aaaagtttaa tccaccgaat gcaaatacct tttggggacg gctgttcaac caaaaattca
     6541 ctagatcaaa atgatgggta gatttatgaa caagaagccc gccgctattg tgcttatttc
     6601 gatgccatct tctgaaataa tctgccccgt gttgcgtatt taacagccat tcgaagtgga
     6661 tagaaaacac atcaccaatc acatcacttt ctatcagttc ctttatcttc gtgtgatacg
     6721 gtgcataacg ataattaaaa gtgactcgca ggcttcttcc cgtctgtttt tggaccgtta
     6781 ttatttcttg agctttttcc tcatcgatag tcagaggttt ttcgcaaata acatcatatc
     6841 cttttttcat tgcacgaatg atataatcat gatgcgttcg atctactgac gtaataatga
     6901 cttcagccgg ccgtacgtca tccagtagtt gctcaaattg tgatggcata catgtcttta
     6961 cttttttctg tccatacttg ttcacaagta tccgatttgc ataatccatc cttgtttgag
     7021 atacatcaca aaaaccgact agttcacaag tttgatgata cgtagaggca attgtctcat
     7081 aaaaaaaacg cgctctccca ccaagtccga cttgtacata ttttttcttc atttaaagtc
     7141 attctccttt tcttttaagc aaaatactgt gacaaatggc agccctggat acagtaatgc
     7201 agtgagtaaa aaatcatgct gtatacacca gaacagtcca tacaaaaggc ataaatacca
     7261 cagaaacccc ttgacgtttt ttgacaacag ccagatattc cttttgatca aataaacaag
     7321 actatctgct ttatcttctt tgcagatatc aattagcgta ctaaaaaaac tatgggatac
     7381 aaaaagcaac agacacaata gaaaaggaat cagataccaa gctccaatct ttcccactaa
     7441 taaataccaa tcaactgcaa aaataatgac aaacagctga aacaacgtaa tgatgaaaca
     7501 catccgtttg atttttcctt tcctccaaca tacctttttt tctgccaagt aatggacaga
     7561 tagataataa gaaggataca tcatcaaaaa ataaatcaga tagacaacac gagcagacag
     7621 cactaatcct aaagtgaaca aacatcctag aactaaagcg aaaagagcat tactgataag
     7681 actggttaaa aaaatccgac agacatagta gttgagcttg taaagaaaca tctcttctat
     7741 tggctttttc atattcagcc cttcagaccg cttgtactga tcccctggac aagatattta
     7801 ttgaagaata agaaaatcag aaaaaccggt agcagcgaca acgtagacat cgcaaacata
     7861 ctcgcgtaag tcgtactaga tccagcgtct gcaaataatt tgatggcaat cgataccgtg
     7921 taagatctcg gcttgtttaa ataaatcaat ggtcccatga agtcgtccca tttccaataa
     7981 aactggatga tgatcgtcgt gatgatcgaa ggtttcagca aaggaaaaat aattttggta
     8041 aagacactat acttgctgca tccgtcaata atcgctgatt catctaactc tttggggatg
     8101 ctgaccatga attgcatgat ctggtaaatg aaaaatgctt gtccaaaaaa atgtggtaaa
     8161 atcagcggca catacgtccc aaccaaattc agccgattgt aaataataaa ctgcggaatc
     8221 aaaatcactt gtgcaggaat catcatcgtt actaacatga cgacgaacca gaatcttttt
     8281 cctttgaaat cgattctcga taatgcgtaa gcaatacaag tcgagctcag aactgtccct
     8341 atcgtcgaaa ctgcagagat gacaaacgaa ttcctaaaga aagtaaaaaa tgaaattcca
     8401 gcaaaccccg cccatccttt tgcgtaattt tcccattgaa aagtctctgg aatcaaattc
     8461 agcgaaccac tcataatctc ttgatccgtt ttaaaagaac ctgcgatcat ccataagacc
     8521 ggataaatca tgactagacc taatagcaaa ataaaaccgt attgaaacca tttcgttact
     8581 gtattattca tttcttcctc ctctcattca cacaacgacc catttttttg atgatttgaa
     8641 aatcagaaag gtgacagctc ccataatcaa cagcatgatc cacgaaatag cactagcata
     8701 ccccatagaa ttaaaagaaa aagcttggtt atacacataa agagcataaa agttcgtggc
     8761 atcattcgga ccaccttggg taatgataaa tgcctgcgta aaagtcataa acgccgcgat
     8821 tgtctgcata accaagttat acaaaatgat cggcgaaaga agaggtaacg tgatcttgta
     8881 aaacgtctgc catttgttcg ctccatcgat ctctgccgct tcataatacg agcctgggat
     8941 ctctttgata cctgcagcaa agatgatcat tgccgaaccg aattgccaag cagacatcaa
     9001 aacaagaggg atcatgacca gtttttgatc gctaaaccag gaaagcgcag gtgcgcctaa
     9061 tcgttccagg aaaatattca ctaacccgtt tttagaaaac aactcccgcc aaactagagc
     9121 gatagaaata ctgccaccga tcaaactagg cacataatac aaagaacgaa agaaagtcgt
     9181 tcctttgata ttcctcgtta aaagataagc aatcaataga ccaaagatca gtttcacagg
     9241 tacagatgca aatacataga gaaaagtgac tcggatggag ttcaaaaaac gggcatcact
     9301 cagcatcttt atataattat ccaagccgat ccatgagact ggatttccca aacgataatc
     9361 ggtgaacgaa taataaagtg acaagatcat cggtatcact gttatcaata gaaatcctag
     9421 gatgaatgga gaagcaaata cgtaaccgac cacattgtct tgatccaaga accgttttag
     9481 tttttctttt ttcatgcctt cctcctgctg ctatcctaga atgtttgacg caaactcata
     9541 aagactctct gctgcttctt ctgctgttac ttcttcataa atgacttttt caactaaaag
     9601 attgtattgg tcttgaattt ccggattcaa agcactatca aagacattca cttcgccgtt
     9661 gtccatatcg gaaatcattt ctaaacaatc aaatgtcgct tgcaaagttg catcatctgc
     9721 acgagcgagc tgttctcgaa tattcgacat gattggtaca ccacgttctc cttttaaaat
     9781 ttcattggct tcttcactgt tttgaaagaa atcaataaac ttagcagctt cttctttatg
     9841 ggctgagctt tttgccatac tcagcatttg cgaagaacgt aaagggatac cagattctcc
     9901 atctgctttt ctgcgaggtg gattaatcaa ctgaatctcc atatcttcag gagcccctga
     9961 caatatttct gtcaactggt tacttgatag aaacaccatt gccgcttctc tatccctaac
    10021 cgcctgaaaa gacagatccg tcgtacttgc agctccacca cctggttctg gatgggcccc
    10081 tttgtctacc agatttttac gcagctggaa aaaatctgtt agatagtctg gattttcaaa
    10141 tcccaagctg ttagatagat cttcccgatt ataaaaattc aatcctttct caacttgtgg
    10201 tatttgaata atacagccag ctataaaatc ttcgaatctt gaaatagcat agattcctaa
    10261 ttcttcagtg atttgatagc tgatttgttc aaattcatcc catgtccaat ttgaagctgg
    10321 ttcagggata tttaattgtt caaatatatt tttattgtaa gcaatcgcaa acgaattcac
    10381 cccgttagac agtccaacta attgcccgtc gtaagtcgtc gttgctaaat aggattcatc
    10441 tgcattagaa atatcaatta tcccttgctc cacatattca tctaatggtt caatctgatt
    10501 gatgtattga ggaaattgat tgttcagttg gaaaatgtcc cagatatcat ctgatgctgc
    10561 tagtgtacct aattttgtgt aatatccttc ataatcataa aattcataat cgatcgtcac
    10621 atggggattt ttttcttcat aaagctcgat tacttttact gttgcatcgt gtcggacttg
    10681 cgaaccccac caagccatgt tcagcgtgat ttttttgtca tcttcttgcc cacaagccgt
    10741 caagaagaat aacataacac ttaaagctaa gatgattctc attcttttct tcattctctg
    10801 cacctctact tccattgtta tttttcaata tactgtattt ttatacagaa catatttatt
    10861 aaacgatctt tttcaagggg aataaaaacc aagacttgcc ttatcgttct gcctaggatg
    10921 aacaactcaa tactttcaag aaaaattaga tagtgctgat tcttctttca tcgctaaaaa
    10981 cacttcttgc ttcaatgatg ggaggataat tacgcaaaga aaaaaggata tcagacaact
    11041 gcccaatatc cttgacatag ctaaataagc atgcttcttc gtgtgcgctc ttccctaaaa
    11101 aacagaaaaa taactagtaa ttctgtatga aattaggtac aatatacacg tcgatgcaca
    11161 agcattgact atggcaactt gattggtcag ttcccgctga cttttcaagc cccgacaatt
    11221 tagctgctac taaattgtcg ggtgcctttt ttagttttta ttcgtttttc attctataga
    11281 aagcgcttca ataaatcaag acattttttt gttagaatgc taataataac aaaaggtttt
    11341 aactcttctt atgtacatta caggtaaaaa aacaaaaaaa tttctctttt ttttgaattc
    11401 tgaacaaata gtactggagt acaaaagacg aggaagagcc actatctgct cttcctcgtc
    11461 ttttgattct cacctgttat tcatgattct ttttctcagt ttcccgatat ttttccattt
    11521 tacgactaaa aagctctccg ctacttggtg gcgtatatgt gatggcattt gctcctgctt
    11581 gaatggtctc agcaatactt tcttccgttg gaccacctgt cgcaatgata ggaagttcag
    11641 gatatttttt acgaaaatgg cgtactgctt ctgcagtttc tttacctgca ctgatattga
    11701 taatcgaaat accagctgct aacttttcat ctatttctgt atatttcgac gttaccgtac
    11761 tgataactgg aatatcaact actcgacaaa cttcttttac tgtctctaaa ggcgtaggac
    11821 cgttcaaaac gacccctaac gaaccttgcg cttctgcgaa catgctcatg taggaagaac
    11881 gagcaccttg tgtcaaacca ccacctacac cggagaaaac tggaatgtca gctgcctcaa
    11941 taatgctttt agtaatcgct ggatgaggtg taaaaggata cacagcaatt actgcattcg
    12001 catttgtatt acgtatgatc gcaatatccg tagtaaagat gatcgaacgg atcaattttc
    12061 caaatatctt gatcccgctt gcttctaaaa tgatttccgg tactcttacg atatcttttc
    12121 tcaattccgt catgatttct ggcgtaaatt gttctgccat cagccacttc tcctttgcta
    12181 tctccggtca tactgattca attgatacgt ctcgatgacc tggatgattt tttgcgcata
    12241 accggggtct gtcgcataac ctgcatcttg caatgcttgt gcggcttcct gatagttggt
    12301 ggccgtaatc actttttcat acagcgcagg attccaatct actccttgga cgaacagttg
    12361 tgtatggtca tccatggact gttcccatga atcatacact ttgaagtctc cttggatagt
    12421 tatccattct tcgttaacaa attcctttgt ttccaggctt actttcttct gatccccata
    12481 agccttgatc ccgaaaagat tattgtattt gctagccaag gtactttttc cccaatttga
    12541 ttctaatata gcttgtccta aaatgatact aggaagcact ccataaccat cttgtagttc
    12601 ttgggcatgc ggaacaagcc gttcaataaa ttgctgatgg gattgcgctt cattttcttg
    12661 ctgattatca gtaaaaggag aagacagatt cttcaaggaa aaaacaaagg ctaagagtat
    12721 cactgctaca ccggcaacca ctgctggcca acggatattc ttgcgctttt gctttttcca
    12781 cttttttttc gccatgatca attcctactt ttcatttaat tcattcagat attcttctag
    12841 cgtcaattgg tgtttggtga tatactcagc gttttcttta ccgacataac gtaagtgcca
    12901 aggttcatat gtgatcttag ttatatcttc gtgtcctttt ggataacgaa cgataaatcc
    12961 atactgcgca gcattatctg cgatccattt agctccaggc tgatctccgt aacttgcatc
    13021 caatacagta gaaggataac tgttgtacca gttttgatcg acgacatcga ctgccagacc
    13081 tgtgtggtgt tcgctgtatc ctggctccgt aatcgtttct ttagtaatct ttgtcgcctc
    13141 ctcttctgat acaccttgac gactcatcac atcttggaca ttttgttcga aaacttgttg
    13201 ttgggatgat acagaccggt aagctgagac catcactaat ggaaatccag ctgcttcagc
    13261 agccttggca aatgcttcat attctggagc aatgcgtttg tcgatcaagt atccgttact
    13321 taatgatgcc aattgagtag actcatcaat ttctttttct aatttgtgat ctggaccaac
    13381 caaaactagc ttccaatcgt ctgttttaac atctggcaat tgtttggacg tacgatcttt
    13441 tgtttctttg tcctttacct tgctgctggt tgtttgactg ttcttttctt tactagcagt
    13501 tgttttggtg cttgttcgtt cgactgcttg attgccggct tgaacatgcg aatcatcatc
    13561 gctaaaaata acatagccca ttgctgcgat cataatcaca actgctccaa atcctaaaaa
    13621 tttattcact tgaaaaatcc tttcgttgtt cttcacgttc cccattcgcc tcatgaacgt
    13681 aagtttcttc cagattttca ttcacccaat cgagaagttc gattttttct ccttcgatct
    13741 gtttttgaac atctgctggc agacgaaaat tcaaaatatc atcatagccc cattcatcat
    13801 attgaatact tactttcaag tcaaggtatc taccagcctg ctgattattt ttcaaaggga
    13861 tcagctcgac ttttgctgct ttgctgctaa gccatttttg cgcgatgcgt gttttgattt
    13921 gcttgtactc tgcaacggca acgtttcgtt tttcgggaaa aataatcgtt tgacgcaaaa
    13981 tcttttgcgt tagcatccat tcataatcag tgaaaagatt ttttactttc tgcatcgctt
    14041 cagatggcag atttttctcg ccatctttcc atttttgcca ttgttctgga ctgatcagca
    14101 agtattcatc taaaaaattt ttttcagttt caaactgttc taataataca ctcataataa
    14161 gatcaatata tacttgatgc acgtttatcc cctcctttta actattctac ttaagttttg
    14221 atcaaaaagc acctcttaaa tcgctgcttt catttttttt aatgtttcaa gtcctctcct
    14281 ctttattctt cgtgattttt gttataataa tagacagaca agaaactcaa tccaactatg
    14341 aaggagcgtt ttcagatgaa aaaatatcaa tggggaatcg ttggtcttgg taccatcgca
    14401 catgagtttg ccgaaagctt caatcaagag acgagcgaac taacagcagt tgcttccaga
    14461 acttcagaaa aagcggaaaa cttcgctcac cgttacaata ttccaaaagc ttacggaagc
    14521 tatcaagaaa tgttagacga tgctgaaatc gacatcgtgt acattgctgt accaaataga
    14581 cagcatatcg accatatctt ggcagcattg gaagcaggca aacacgttct atgtgaaaaa
    14641 gccatcacga tgaataaaaa agaactggct gacgctatgc gcttagcaga agaaaagaat
    14701 ttgatcttag cagaagcgat gacaatcttc aacatgccac tttatcagca gttacgctca
    14761 ataatggata caggaaaact gggggcttta aaaatgatcc aagcaccttt cggcagttac
    14821 aaagaaccag accctaaaaa ccggttcttc aatccagaat tagctggagg agctctgttg
    14881 gatatcggta cgtatgctgt atctttcgct cgtttctttt tgagctctca acctgaagta
    14941 gttgcctcta caatggttcc ttttgaaaca ggcgtggacg aacaatccgt cactatcttg
    15001 cgtaacaaag aaaatgaact tgctgctgtc agcttgactt ttcaggcaaa aatgccaaaa
    15061 gtcggtatcg ttgcctttga gaacggttat gtgacgattg ctgattaccc gcgtgctgat
    15121 cgtgcggaga tcttatttac agatggtaca aaggaattca tcgaaagcgg gaatacatct
    15181 gaagcaatga attacgaaat aaagaatatg gtacacatga ttgaaggtga cttgcccaat
    15241 cgctctctct tcttgacaaa agatgtcatc gaaatcttgg atcaaatgca agttctatgg
    15301 aaaaatatgt aattttaaaa ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    15361 ccaaacaaaa atagctcctc ctatttttcg tttggctgga cttattaccg cagaggaaag
    15421 cttttgaaca ccgtttaaga aagaggttgt gagcctaccg ttcagctccg agtcacaagg
    15481 agcaatttca aaaaacagct tctcatgttt gttgaatatt gtgacttgtg accgaggagt
    15541 tgacaggaga acaccgttta aagaagaggt tgtgaaatca gctttttgac ctgaatatta
    15601 gctgaattca caacctctat ttttggattt tttgttggga gaattctgcc ttgatttcaa
    15661 taaaactttt aaaagactgc aaaaactgga acaattctgc tcgatcctcg aattcagggc
    15721 gactagtcgg cagaggcatt tgccgataca atacataaac ttcttcaata cgtgttaaaa
    15781 tttgtctgcc atcatttgac tctgaaaatg tttctgcagt ataaatcaat aaaccataga
    15841 tatgttttcc ataataagct ggttgctgga ttctctctag attttccagc atgtctttaa
    15901 tcacattggc ctgtgctctt ctcatagaga agtaagtttc gtagtatagc ggctgtctga
    15961 gccagtagtt ttcttgatgt tctctggcat cttcttggct ttcgcgaatg aatgtcagta
    16021 aatgttcgca tttgatctgc acatcttctt tattttctga taaaagaaat tctgccattt
    16081 gtctcaaaat atttcgaaat tctttttcga tctgtatttg gttttccttc agctgcttcg
    16141 tacgatctgg catgtaaaca tttgcaagca aagcaaatac taatccaatc gccattaatc
    16201 ccgcttcatt gccgatcagc tgccaagaca tgttttcctc cactaaataa tgagtgacca
    16261 aaaccgaatt tactactatc ccttcggtta atttgaagcg agaggcaagc gggatgaaca
    16321 ggaataaaaa aagactgaag ccaaaaatag tatacccaac agcaaaaaaa ctgaacagtg
    16381 ctgttgccgt agctaatata aaggctgcga ttcgattcat gcccgtacgc aatgtagagc
    16441 gcttggtatt tcctacactt aataatgcaa tgatccctgc agctggccaa tacaacagcg
    16501 ataagctacc cgctgtgacc atcgaaaaga agacactgat cactgttttg actgttcgca
    16561 ttcctatacg catttacttc cccctttttt attttaatta tacttgaata atgaaaaact
    16621 agctatcaga caaaagttta ggtatgatag taaaaagacc aaaaaggaga atctctatgc
    16681 aatttggccg ttttcgacta ggtatgcgta cgatcaaaag tgccttagct gtttttttat
    16741 gtatcttgtt ttttcatttg actcaacgag gaatcccgat gattgctgca ttatctgctg
    16801 ttttttcttt gcgtcaggac ttgactacaa ccgtttcttt tggaaagtct aggatcatcg
    16861 gcaatacatt aggtggtaca ttagctatca tttatttttt tgtcaaaagc tattttcaca
    16921 atgatttttt ggtagaattg atcttgcttc ctattctagt tattattgtg atcgtcgtgt
    16981 cagatggtat taacaataat tccggtatca tttccgcaat agctacgttg ttgctgattg
    17041 cgttgagcat ccctcaaggc gaatccgctt tgtatgctat ccaacgtgta ctagatactt
    17101 ttatagggac attcattgca atcggtatca atttctttct tcgtcctcct gaaacagaaa
    17161 agaaggaaga actatcagaa gatttggtcg aactccaaaa gaaagaacga ttgctaagaa
    17221 caaatttaca agagatagaa gctaagatcc aaaaacaaaa gaaaaatagc gaggactaat
    17281 tttcttttgc aataaaataa aaaaatggag agaagaactt taaaaagtct tcctccattt
    17341 ttgattgaac ggtgaagtgt actactttat tcttccttca tcgagttttg ttctgcctct
    17401 tttggcgctt catacatatt tacttggcta gtagtcccac gtgtcgacaa attctctacg
    17461 atttccttca agtcaagtcc tgttgtcgct tttagtgttt cttgagtaga agaaagcaaa
    17521 tttgtggcat aatttgtcac tcggttcgct ccactggttt ctcctgaact gcttcctgta
    17581 tcgacaacag agattttttc gatatttcct agcggctgtg ctgcttcgcg catcaattgc
    17641 ggtagcatat cgataaccat actcaagaca gctgcttcgc catattcctt gaaggcattg
    17701 gcgatctttt gttttgcttc ggcttctgct tttccttttg ctagtgctgc ttcggcttct
    17761 gcttgtccag ctaaacgtgt cttattggct tccgcttctg ccagtgcttc cacacggaat
    17821 cgttctgctt cggcttcagt cacttctttg actttttgag cttgtgcttc ttgttcttta
    17881 gcgtaccgat cggcatctgc ttttttcttc acttccgaat catattgctt ttcacgacgt
    17941 gtgatttctt tttcttccag ttcgatttgt ttttgacgtt ctacgatttt aatctgcatt
    18001 tcctgttcga ttacttgttg ttgtgctcgg gcactttcta aattgtaggc ttggtctgct
    18061 tttgctttag caacatcttg ttcttgtttg taggttgcta atttcagttc tttttctttt
    18121 aatgattctg cgatctctgt ttgtcgctgt aattcagctg cttgtgattc tttttctgct
    18181 tgagcttttt tgatacgcgt ttcttttaga gcttccgctt ctgctatatc tgcatctctt
    18241 ttgacttggg cgattcttgg tttccctaaa gagtcaagat aaccgttttt gtctctgacc
    18301 tctttgatag tgaaagaaac gatgatcaac cccatttttg caaggtctac agaagcgact
    18361 tcttgtacgc tttgactgaa cttatcgcga ttttgataga tttcttctac agtcatagaa
    18421 ccaagaatcg agcgcaagtg tccttctaat acttctcttg cttcattttc cagttcttct
    18481 cttgtcttgc ctaaaaactg ttctgctgct gtagcaatct cttctacaga tgaaccgatt
    18541 ttgatgatcg aagtaccatc acacatcacc ggtacgcctt gttccgtata cacttcaggg
    18601 gtggagacgt ccaatttact cgataataga ctgatccgat tcgaacgttg aaaaactggc
    18661 aagacgaatg cgccacctcc acgcacaatt ttgattttgt tattgctttc atcaatgtgc
    18721 acatttttgc ttcctaaata acttccactg atgatcaacg cttcatccgg ttttgctgtc
    18781 tggtacttcg ctacaaagac gatcagcaac atcagtaaaa tcaaagctgc gattgcgatc
    18841 gcgataaaaa caactggtat ttccatttaa cacacgctcc tttaagcttt tatcatgctt
    18901 tcataaggca tgacataaca gattctttcc ttgatctcaa tgatcaatac tttcgttccc
    18961 cgctcagctg tctgttcttg ggggctgtaa aaacaagctg gacgactaat ggaaccggta
    19021 acacttttca actgaatttc tcccatacct cgtacaggga tcggtgtgat cacaacagct
    19081 acttgtcctt ccagagtttt ttcagaagac gacatcgttg attcggcatg tttcatcggc
    19141 atcaatatat agaaattaag caaaaatacc aacactatcg atatgcctcc actagcaata
    19201 aataaaaata aagatgattg atctgttaaa cgctcaccta gaaaaccaaa taagcttgtg
    19261 aaagttaacc aagggataat aagcatcgga tcaagcgggc catcaaaatc gaatacatct
    19321 ccaaaaataa tcaataggac tgccaatcct gcacaaatca gcaatgtata ccaataaatc
    19381 gtctcaagtg cgattccccc tatcatatac acgcctcctt ccatttctac gtctatcata
    19441 ccaatgtttg aaaattctgt atagcttctt ttaccgactc agtggtgttt tttataggaa
    19501 ggttgtgttt atcgttgaca atttgttaaa tttttgtttt catgttaaaa ttttcacaat
    19561 aaattctttc gaggtagcct atgtttcctt tttttaagaa aaaaccatta aagctccaga
    19621 acacgatcat ccttgtcgtt tgtttctcca cattcgtttc tttgattgtt tctgccatat
    19681 tgatcaggaa ttttattctt tcgatgaacc gatctagtgt gtcagataaa atctctagca
    19741 ttgctaaaat cgttgccaat gataaactca tccaaaaaaa gctgcagact ggtgacccga
    19801 cacatgcgat tcaaggaata acaaatgaaa tcatgattgc atcgaattta gattttatcg
    19861 ttgtcatgga ccctgaaggc attcgatatt ctcacgcaga cccaagttac atcggtcttc
    19921 ctttctcaag tcatgaagat gtgaaaaaag tgattggagg acaagaattt ttctctgaaa
    19981 aagaaggaat gttagggttc ggcttccgct atttcgtccc tatttattat gatcaagaga
    20041 ttattggtgc agtttgtgtt ggcttaacaa acaacacgat tgacaatcaa gtcaaagatg
    20101 gacaaaaaat gattgttttt tcattgatta ttggacttag cgtaggcatc ataggcgccg
    20161 tttttcttgc ccaaaaaatg aaaaaagtac tgcttggact tgaaccacaa gaaatagcag
    20221 aacagttaag tgaaaaaacg attatcgaaa atgaagtaga tgaaggaatc ttagccatct
    20281 cttctgataa aactatcctc ttgatcaata cacctgcaaa aaacattttc taccaaacag
    20341 agcagctatt ggatttcgaa gtaggaaaaa aatcagtgat aatctatatg acgttttgtt
    20401 taaagagacg attgagcatc aaacgaccgt tcggactcaa tccatgtatt taaatgggat
    20461 agaaactatt tctagcgtta cacctctttt tagcaatgac cgttttttag gagcagtcgc
    20521 aactttacga aatcgatcag aagtaatgaa attaatggag gagcttgggg ggacgaaaca
    20581 atatataaac tccatgagag ctcaaaccca tgaattcatg aataaacttc atgtcatttc
    20641 tggtttgatt gatttgaaga agtatgaaga agtcacccat tttatccagc agctaaatca
    20701 aaattataaa aaagagattg gccaagtctc aagtctgatc aaagtacctg caattgccgg
    20761 ttttttatta ggcaaaataa acgaagccaa agaacaatct gttgaaatgc tgttagaaag
    20821 cgattctttt atccctaaaa tggagatgga tgactccatc cattcacttt tgcaagtgtt
    20881 agggaactta cttgataatg caaaagaagc cgtgctacaa aaacatgaaa gaaacggaca
    20941 ggtccggatt catttaaact atgacacaga agctgaagta ttcatcgtga ccgtctgcga
    21001 tgacggtgtc gggatatcag aagaaatctc agaaaaaata tttacgctag gtttttcgac
    21061 gaagggaatc aatcgtgggt ttggattgaa tctcatccat tcaatcgtca aacgccacgg
    21121 tggattttta gaattttcca aacaaacaaa tggcggtaca atcgtctatc tagaattacc
    21181 aaaaaaggaa gatcaaaatg atgacaaatg tcctgataat cgaagatgat ccaatggttg
    21241 cagaattgaa tcgtactttt gtggaaagca tccctaatat gaacgtaatc gaaagtttca
    21301 gaaatgtaga agaaggaaaa aaatatttca gacaaaaaaa cgcagatctg ctgctgcttg
    21361 atgtatacat gcctggcgaa agtggtatcc attttttatc ttggcttaga cagcaaggaa
    21421 atgatatccc agtgattttg atcactgctg cagatgatat cgaaaccata aagaatgtga
    21481 tccgctacgg tgccttagat tatttgatca aaccgttcac tttgcaacgt tttcagctgg
    21541 cgatcgaaaa gtatcttgct ttctctcaga caatccaaac gactgaaaaa gccgatcaga
    21601 aattgatcga tcaagtattc aaccacacca ctcccattca cgaaatacca tcattcatcg
    21661 atttgcctaa aggtctgtca aaactgactt taaaaaaaat aagtgcattt attctaaaag
    21721 aagatactat tttttcaaca aaagaactgg ctcaaaaaag ctcactgtca cgtatatccg
    21781 tcaagaaata tttgaatttt ttagtagaac aagatatatt gaacgaaaga atcaaatatt
    21841 tggaaatcgg ccggccgcta acctgttatg aattgacaaa gaatgggcgg aaaaagctca
    21901 cagattactg ttgagtcatc gaattatccc atacaaaata gtccaagtat acagaagtaa
    21961 caactgttta cttggactat ttttaaacat tttattgacg aatatccatg ttttcttatc
    22021 ttaattgacg ggctttagga agagatacct catttttcgt ttttccagtt tctattattt
    22081 cacgaaagtt ctcgaaactt gtcgaaatca tatttgataa tgcctcatct gtatttgaac
    22141 ctacatgcgg ggttacaaga actctagggt acatttctac taattgctgg atagcagggt
    22201 ctggaatcgt ctcccatggc ttgaaggatc ggaaaaaaac ctctgtttca tttgcaaaaa
    22261 catcggttgc aaaaccagct aaatgattgc ttttcaaagc tcttaaaata gcttcattat
    22321 cttgaagctc tccacgggct gtattaatca agatgctacc ttttttcatt tgagctaaaa
    22381 atccttcatt gatcatttga tcgttttcac ctgggatatg aggtacatga atactgacaa
    22441 tatcgctttt ggctaataac tcttcaagcg agtggaacgt caatactttt ttagcagctt
    22501 ctgtctgatg aatatcgtag ccgatcactt tggctcctag tcccttaaac aaaacagctt
    22561 ccgtcaaccc tatcctgcct gttcctatga tccctactgt gcaatttctg atttcacgac
    22621 taaacatttg ctcatccact cgaaaatctt tgaaagatgt tcggatcgtc gtatacgcag
    22681 tatttctcaa aagcatcatg gcaaaagtca aagataactc tgctatcgca tttggcgaat
    22741 acgatggtac acgggctact gtcataccaa aatcagctgc cgcttgtaga tcgatatgat
    22801 tgactcccac agtccgtgta aaaacataac gaatcccata ttcctgcatt tttgcaagat
    22861 tggtctcatc tgctatacaa tttcccctca acaatacagc atcatggtcc tttgctgaca
    22921 cgatattgtc atgtgtcaac agttcttcat aaagactgag atcataatgg taaatattca
    22981 atttttcaaa aaaatctatc tcgttcggac gaacaccgta acatgcgatt ctcatacttt
    23041 cttcctccat ttcttatgaa aataaaccta tgccatgaat catttgtaat acaacgatcc
    23101 atacaggtgt cagtaccaca gcaaaaatag ttgacagtaa ggatgcattg gaggctaaaa
    23161 gtgcctccct atcaaaactg atagcatagg ctgctgccac tgttgcagct ggtgtagcca
    23221 tcatgataac gattgttgcc agtgcttcaa aattgactgg tagaatattc gttgccgtca
    23281 aaactgctag aatcacgata ttcaatgcag gtacaaatac cactttgact agactgtaat
    23341 accatgaagt tttttcagat gcagcttttt tgaagcttac ttcacctaat gttgcgccga
    23401 ttgctagcca cgccaatggt gaacttaaac cagctaaata atccatcggc tgaaatagcc
    23461 acggtgcagt ctggtcaatt cgcaaaaacg ctacttggct tatctctcct tctgcacctg
    23521 taactgacac ttgtggcaga tacccttgga acagccaaat gaaaaggccg gcaaaagtag
    23581 cgataatgat tggattgacg aacatcgctt tgatattttt agcttccatc ttcaagccac
    23641 tcatttttat gtatccataa gaatacaaaa agattcggta gccaatattg aaaattgagg
    23701 aatacatcac gccgacagga ccataaatcg cactgacgat aggcgttccg aaaaaggtcg
    23761 tagaaccaaa gatcgtcagg acacgcaacg ttgtttgctt atccccttta tagcttaaga
    23821 aaaaaggttt tgaaactaga ataagaataa tataaataac taatccccaa atcaagacat
    23881 tgattccttg catcagtaat tctgtattga tatcttgcat gaaagctcga aatgccagtg
    23941 ctggcaaagc cactgttaag acgactttcg atagaatttt tccaacagat tcagaaaaaa
    24001 tccccttttt tctacaaaca aaccctaata atataataaa aactgttgaa gtgattgcac
    24061 tgacaatcga catatctgtc aaagtcgatc gaaaaatgtc aaataagttc atctttctcc
    24121 tcctaattat gttcatttat tcacaataaa aaaagctttt attttgctaa tacgtattaa
    24181 catttttaat tttatcttta cattgttact tattgaacaa taggaaatta aagaaacttt
    24241 tgaaacttat gtaaagtgat ttttactaga acacaaaaaa aac
//
LOCUS       DBGZHO010000039        24271 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.039, whole genome shotgun sequence.
ACCESSION   DBGZHO010000039 DBGZHO010000000
VERSION     DBGZHO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.039"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..572
                     /locus_tag="ACN3HL_001774"
     CDS             <1..572
                     /locus_tag="ACN3HL_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HHC8006633.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="ACN3HL_001775"
     CDS             576..1217
                     /locus_tag="ACN3HL_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006634.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="ACN3HL_001776"
     CDS             1214..2131
                     /locus_tag="ACN3HL_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8006635.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="ACN3HL_001777"
     CDS             2128..2799
                     /locus_tag="ACN3HL_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8006636.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="ACN3HL_001778"
     CDS             complement(3340..3828)
                     /locus_tag="ACN3HL_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HHC8006637.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="ACN3HL_001779"
     CDS             complement(4029..4295)
                     /locus_tag="ACN3HL_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HHC8006638.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="ACN3HL_001780"
     CDS             complement(4295..4558)
                     /locus_tag="ACN3HL_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HHC8006639.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5079..5219
                     /locus_tag="ACN3HL_001781"
                     /pseudo
     CDS             5079..5219
                     /locus_tag="ACN3HL_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..7184)
                     /locus_tag="ACN3HL_001782"
     CDS             complement(5361..7184)
                     /locus_tag="ACN3HL_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HHC8006640.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="ACN3HL_001783"
     CDS             complement(7782..10487)
                     /locus_tag="ACN3HL_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HHC8006641.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="ACN3HL_001784"
     CDS             complement(10793..11740)
                     /locus_tag="ACN3HL_001784"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HHC8006642.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="ACN3HL_001785"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="ACN3HL_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HHC8006643.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLHKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="ACN3HL_001786"
     CDS             complement(12375..12737)
                     /locus_tag="ACN3HL_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HHC8006644.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACN3HL_001787"
     CDS             complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACN3HL_001787"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HHC8006645.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACN3HL_001788"
     CDS             complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACN3HL_001788"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HHC8006646.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="ACN3HL_001789"
     CDS             complement(14365..15876)
                     /locus_tag="ACN3HL_001789"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HHC8006647.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACN3HL_001790"
     CDS             complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACN3HL_001790"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HHC8006648.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="ACN3HL_001791"
     CDS             complement(17703..18779)
                     /locus_tag="ACN3HL_001791"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HHC8006649.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="ACN3HL_001792"
     CDS             18975..20720
                     /locus_tag="ACN3HL_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HHC8006650.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="ACN3HL_001793"
     CDS             complement(21000..21437)
                     /locus_tag="ACN3HL_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HHC8006651.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="ACN3HL_001794"
     CDS             complement(21421..22794)
                     /locus_tag="ACN3HL_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006652.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="ACN3HL_001795"
     CDS             complement(23116..23604)
                     /locus_tag="ACN3HL_001795"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006653.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="ACN3HL_001796"
     CDS             complement(23626..24228)
                     /locus_tag="ACN3HL_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HHC8006654.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5163 c         4487 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcat aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DBGZHO010000040        23827 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.040, whole genome shotgun sequence.
ACCESSION   DBGZHO010000040 DBGZHO010000000
VERSION     DBGZHO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.040"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(53..787)
                     /locus_tag="ACN3HL_001797"
     CDS             complement(53..787)
                     /locus_tag="ACN3HL_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HHC8006655.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACN3HL_001798"
     CDS             1114..1524
                     /locus_tag="ACN3HL_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HHC8006656.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ACN3HL_001799"
     CDS             1517..2218
                     /locus_tag="ACN3HL_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HHC8006657.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ACN3HL_001800"
     CDS             2218..3804
                     /locus_tag="ACN3HL_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006658.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ACN3HL_001801"
     CDS             3823..4044
                     /locus_tag="ACN3HL_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HHC8006659.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ACN3HL_001802"
     CDS             4041..4802
                     /locus_tag="ACN3HL_001802"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HHC8006660.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ACN3HL_001803"
     CDS             5182..5691
                     /locus_tag="ACN3HL_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HHC8006661.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ACN3HL_001804"
     CDS             complement(5766..6305)
                     /locus_tag="ACN3HL_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HHC8006662.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACN3HL_001805"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACN3HL_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HHC8006663.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ACN3HL_001806"
     CDS             7318..8169
                     /locus_tag="ACN3HL_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HHC8006664.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ACN3HL_001807"
     CDS             8197..8832
                     /locus_tag="ACN3HL_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HHC8006665.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ACN3HL_001808"
     CDS             8852..9625
                     /locus_tag="ACN3HL_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8006666.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ACN3HL_001809"
     CDS             10033..10830
                     /locus_tag="ACN3HL_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HHC8006667.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ACN3HL_001810"
     CDS             10808..11221
                     /locus_tag="ACN3HL_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HHC8006668.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ACN3HL_001811"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ACN3HL_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HHC8006669.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ACN3HL_001812"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ACN3HL_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HHC8006670.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="ACN3HL_001813"
     CDS             15998..16558
                     /locus_tag="ACN3HL_001813"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HHC8006671.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACN3HL_001814"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACN3HL_001814"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HHC8006672.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ACN3HL_001815"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ACN3HL_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HHC8006673.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ACN3HL_001816"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ACN3HL_001816"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HHC8006674.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ACN3HL_001817"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ACN3HL_001817"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HHC8006675.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ACN3HL_001818"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ACN3HL_001818"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HHC8006676.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ACN3HL_001819"
     CDS             21905..22483
                     /locus_tag="ACN3HL_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8006677.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ACN3HL_001820"
     CDS             22535..23017
                     /locus_tag="ACN3HL_001820"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HHC8006678.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ACN3HL_001821"
     CDS             23134..23508
                     /locus_tag="ACN3HL_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006679.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atagaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DBGZHO010000041        23571 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.041, whole genome shotgun sequence.
ACCESSION   DBGZHO010000041 DBGZHO010000000
VERSION     DBGZHO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.041"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACN3HL_001822"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="ACN3HL_001822"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HHC8006680.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="ACN3HL_001823"
     CDS             complement(1172..1867)
                     /locus_tag="ACN3HL_001823"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HHC8006681.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="ACN3HL_001824"
     CDS             complement(1880..2596)
                     /locus_tag="ACN3HL_001824"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HHC8006682.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="ACN3HL_001825"
     CDS             2926..3531
                     /locus_tag="ACN3HL_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HHC8006683.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="ACN3HL_001826"
     CDS             3856..4179
                     /locus_tag="ACN3HL_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HHC8006684.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="ACN3HL_001827"
     CDS             4361..5731
                     /locus_tag="ACN3HL_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HHC8006685.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="ACN3HL_001828"
     CDS             complement(5861..7162)
                     /locus_tag="ACN3HL_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HHC8006686.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9383)
                     /locus_tag="ACN3HL_001829"
     CDS             complement(7392..9383)
                     /locus_tag="ACN3HL_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HHC8006687.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="ACN3HL_001830"
     CDS             complement(9527..9793)
                     /locus_tag="ACN3HL_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHC8006688.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACN3HL_001831"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="ACN3HL_001831"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HHC8006689.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACN3HL_001832"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="ACN3HL_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HHC8006690.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /gene="def"
                     /locus_tag="ACN3HL_001833"
     CDS             13137..13700
                     /gene="def"
                     /locus_tag="ACN3HL_001833"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHC8006691.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="ACN3HL_001834"
     CDS             complement(13953..14474)
                     /locus_tag="ACN3HL_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HHC8006692.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="ACN3HL_001835"
     CDS             complement(14477..15319)
                     /locus_tag="ACN3HL_001835"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HHC8006693.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="ACN3HL_001836"
     CDS             complement(15312..16037)
                     /locus_tag="ACN3HL_001836"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HHC8006694.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="ACN3HL_001837"
     CDS             16213..16509
                     /locus_tag="ACN3HL_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006695.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16765..16939
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17077..18669
                     /locus_tag="ACN3HL_001838"
     CDS             17077..18669
                     /locus_tag="ACN3HL_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHC8006696.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="ACN3HL_001839"
     CDS             18682..19422
                     /locus_tag="ACN3HL_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHC8006697.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="ACN3HL_001840"
     CDS             19590..20939
                     /locus_tag="ACN3HL_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8006698.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="ACN3HL_001841"
     CDS             complement(21067..21657)
                     /locus_tag="ACN3HL_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HHC8006699.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="ACN3HL_001842"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="ACN3HL_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HHC8006700.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DBGZHO010000042        23461 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.042, whole genome shotgun sequence.
ACCESSION   DBGZHO010000042 DBGZHO010000000
VERSION     DBGZHO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.042"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(74..655)
                     /locus_tag="ACN3HL_001843"
     CDS             complement(74..655)
                     /locus_tag="ACN3HL_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HHC8006701.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(661..1920)
                     /locus_tag="ACN3HL_001844"
     CDS             complement(661..1920)
                     /locus_tag="ACN3HL_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HHC8006702.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1922..2968)
                     /locus_tag="ACN3HL_001845"
     CDS             complement(1922..2968)
                     /locus_tag="ACN3HL_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006703.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3203..3478)
                     /locus_tag="ACN3HL_001846"
     CDS             complement(3203..3478)
                     /locus_tag="ACN3HL_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HHC8006704.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3721..5031)
                     /gene="der"
                     /locus_tag="ACN3HL_001847"
     CDS             complement(3721..5031)
                     /gene="der"
                     /locus_tag="ACN3HL_001847"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HHC8006705.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5213..6442)
                     /gene="rpsA"
                     /locus_tag="ACN3HL_001848"
     CDS             complement(5213..6442)
                     /gene="rpsA"
                     /locus_tag="ACN3HL_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HHC8006706.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGGILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6577..7257)
                     /gene="cmk"
                     /locus_tag="ACN3HL_001849"
     CDS             complement(6577..7257)
                     /gene="cmk"
                     /locus_tag="ACN3HL_001849"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HHC8006707.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7306..7941)
                     /locus_tag="ACN3HL_001850"
     CDS             complement(7306..7941)
                     /locus_tag="ACN3HL_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HHC8006708.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(8007..9410)
                     /locus_tag="ACN3HL_001851"
     CDS             complement(8007..9410)
                     /locus_tag="ACN3HL_001851"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HHC8006709.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(9397..10428)
                     /locus_tag="ACN3HL_001852"
     CDS             complement(9397..10428)
                     /locus_tag="ACN3HL_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006710.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10459..10680
                     /locus_tag="ACN3HL_001853"
     CDS             10459..10680
                     /locus_tag="ACN3HL_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HHC8006711.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10845..11582)
                     /locus_tag="ACN3HL_001854"
     CDS             complement(10845..11582)
                     /locus_tag="ACN3HL_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HHC8006712.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11735..13075)
                     /locus_tag="ACN3HL_001855"
     CDS             complement(11735..13075)
                     /locus_tag="ACN3HL_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HHC8006713.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13312..14835)
                     /locus_tag="ACN3HL_001856"
     CDS             complement(13312..14835)
                     /locus_tag="ACN3HL_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HHC8006714.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15213..15824)
                     /locus_tag="ACN3HL_001857"
     CDS             complement(15213..15824)
                     /locus_tag="ACN3HL_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HHC8006715.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15947..16072)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16154..16870)
                     /locus_tag="ACN3HL_001858"
     CDS             complement(16154..16870)
                     /locus_tag="ACN3HL_001858"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HHC8006716.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16876..17445)
                     /gene="scpB"
                     /locus_tag="ACN3HL_001859"
     CDS             complement(16876..17445)
                     /gene="scpB"
                     /locus_tag="ACN3HL_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HHC8006717.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17429..18199)
                     /locus_tag="ACN3HL_001860"
     CDS             complement(17429..18199)
                     /locus_tag="ACN3HL_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HHC8006718.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18196..18567)
                     /locus_tag="ACN3HL_001861"
     CDS             complement(18196..18567)
                     /locus_tag="ACN3HL_001861"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006719.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18586..19473)
                     /gene="xerD"
                     /locus_tag="ACN3HL_001862"
     CDS             complement(18586..19473)
                     /gene="xerD"
                     /locus_tag="ACN3HL_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HHC8006720.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19569..20042)
                     /locus_tag="ACN3HL_001863"
     CDS             complement(19569..20042)
                     /locus_tag="ACN3HL_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HHC8006721.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20147..21010)
                     /locus_tag="ACN3HL_001864"
     CDS             complement(20147..21010)
                     /locus_tag="ACN3HL_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HHC8006722.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21206..23305)
                     /locus_tag="ACN3HL_001865"
     CDS             complement(21206..23305)
                     /locus_tag="ACN3HL_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HHC8006723.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT         6419 a         4992 c         3939 g         8111 t
ORIGIN      
        1 acaaagatag gctatgagga aagattccac atccagctga cctttgtctt ttttagtact
       61 atactatttt taactaattg ttatgttcac ttacccggtt acttttcttt tgtgtctgca
      121 aaaggatctt tcggttaact tcatcagata atttcaaaaa agcatcccta tctccatctt
      181 ctagtgcttg atcgatttga gcataaagca tttttagttt tgcctcttct tctttttctt
      241 gaaaatatcg ttcaattaat tcagtatctt cttcactgac tgaagaatcc caagaagaaa
      301 atggattgtc ttctaagata gatagatatt ctcttgtctg ccaagcattt tcgaatatac
      361 attccacata taaaggcttt ttccaattca aacggatttc atgaaaaatc tggtctgtgt
      421 ccgtaaattc ttttccctgc aaaaacaatt tcatgggttc cccttcaaca gatagatcac
      481 tgatctgcag tcctcgatcc gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa
      541 tcgcttcatg attggcaaga taattcaaga tccaaaaaac ttctcttcgg ctaaaagata
      601 catgattgac catccacgtt aaaaaattct tcttttcccg tacatcaatt agcatttttc
      661 tcacctctct gttaggtcat ctaataatga cagtgcctcc atatctcctg gttcaagtgt
      721 taaataataa gtcaataatt cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa
      781 ggcatactct ttcaagaaat ctggttcatg tgatagttca tgataagcct gttcatagtg
      841 tacagctgca acggtaaagt cttctaattc attataagca tgggctaggt tccattctgc
      901 ataaggatta gcagtttctt ccatctgatt gatcacttgt atcacatctt catatctttc
      961 atcatccaag taaagattac ttaaagtaag taatgtttca tcttgtttgt ctcctacttc
     1021 taaagctttc agtaaaagtt cttctgctcg ctgtctatca tgcagacgga aagcattttc
     1081 cgaggccagg tgataaagtt cgacttggta aggattttct ttgattcctt cttctaacac
     1141 tgtttgtgct tcttcaatca tttcttcttc ttgaagagct tgtcctagat atagatataa
     1201 cgattgataa tgcggattaa cttctcgaag ttcttccaga tagttgattg cctgctgatt
     1261 ttctttcaat tgaagattcg taaaagctag ctggaacagt cgatcatctg tcctttcttc
     1321 tttcagtgct tcttctaaag gtacgatagc tgcttcgaat tctccttgca tacttaagga
     1381 ttgtcctaaa cgttcctgca tcgagattcc tgaaatttca tttatcccgc ttgccaacaa
     1441 tgtttcataa accactgctg cctctttgaa acgatcaact gaaaaataca attcagctag
     1501 cgcaaactgg atcaatggtt catcaggaag caacccagct gcttctttca attttgcttc
     1561 actcacttca gggattccga taacttggta caaatcagct atcgccaata agctttgcgg
     1621 atagtaatca ctttgcttat ccactttttc caggtattca aaagctaagt cgatctcatt
     1681 atcttcgatt gcaatttctg ctaacgggat gttcagtccg tcattttctg ggtattggtt
     1741 gatcagttgt tcaaaaatct gttttgcttc gatcaaaaag ccaatagcca gcaattcttc
     1801 gcctagttca gctaatatat ctgctgggtc ttcttttaat gctttttcta aaaagatttg
     1861 tgcttgtgac aagtcttcat ctgataaagc ttgcaacatt ttttcgctat ttgtattcat
     1921 ttcaattccc tcttatctca ctgacgattt gttgaaatac cgtcattgtt ctcaataatt
     1981 ctttttcgtt tggatgttgg tatccgtcta ttatacctat tttttctaaa acaagtattt
     2041 ttttgctttt ttctgccaaa aaaagaactt tttccaaata ctccatcttt gaaatctgtt
     2101 ccagccagtg gattggatag ccaagcaagt ccagccacac aaaaaagttt tttagttgga
     2161 aatcaaaagg atatgcttgg agattccaca cgaaatgaaa catcattcct aaaaattttt
     2221 tcatactagc agaaagtaga tggccatttt cggtcagata aaaagcttgt tcaaacagtt
     2281 taccataatt tgacaggttt tctgcctcta attgataaaa atagatcatt tcttcgatca
     2341 tcccggcaaa cggccgagtc gttaattgct ttttatttgg atagttttta tacagatttt
     2401 gcaaaaaacg atgatcacaa atcattccgc aacagataaa agtcaaaaag tcaatctgct
     2461 ttccgtccac ctgccgctcg ctgattgttt gatcataaac gatgcgttct ggcagattga
     2521 tggtttgcag cactacacga tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc
     2581 ggcttagaga acggatcgat acagggatca tccatagtga tgaatcaagg gttgtatgtt
     2641 tttgaaaaaa acctgccaga tccatgatcc cttcatttcc aaatccgatg ataaacatgg
     2701 attgattttc gggatagcgt ttgacgaaat caagcaggtt ctttaattct gttaaatgat
     2761 tgcattgagt gttggcacaa atataccagt cattgtttgc ttgatttgca aataacgggt
     2821 tgatcttatc tgcaaacaaa tcataatagc gctgattcgt taaaaataag attggctgat
     2881 caatggaaag ttctcttagc tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg
     2941 catcttctac ttgataatca agttccatac gcatccctcc tcttcttatt tttattttac
     3001 cattagtaag caaattctag aaaagataag agcaaagctc acctcataac ttgcaaataa
     3061 ataaaaatta aataaaatac atgtgttttc tatgtatgac atacggattc ggaatctctg
     3121 tctcttattt attccttttc tgctaggaaa taaaaagaaa agcacttgta gccctagagc
     3181 cacaagcgct ttttcaactg tcttatttaa cagcgtcttt taatgcttta cctggtttga
     3241 atgcaggtac tttgctagct ggaatttcga tttcttcacc agtttgtggg ttacgacctt
     3301 tgcgagctgc gcgttcgcga acttcaaagt taccaaaacc gattaattga actttttcgc
     3361 cgttagctaa agcatcttga atagttgaaa atacagcatc tactgctgca gttgcatctt
     3421 ttttagttaa atcagtagct gaagcaactt tttcgattaa ttctgctttg tttgccatgg
     3481 atagattcac ctcctccaca agagatatga tagaaatatc atttagttaa aactttctga
     3541 gtggtccaga agtttaaaaa gaaatattga ttaacttcaa tattctgtta tcacgatatc
     3601 atatgaaccg cttaatagca aggtttttac caattttcac atgctttttt tagtcataga
     3661 aacgtaacaa acgaaactgt ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc
     3721 ctattttctc ctacgaggga taattcggat ggacgtccct tcaaaagtaa atgcttttct
     3781 gatttgattt tctaagaaac gttcataaga aaaatgcatc aattcctctt cattgacaaa
     3841 aacgacaaat gtaggtggtt tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt
     3901 tcctttatct gttggtgttg gattgattgc tacagcatcc ataatgatat cattcaacac
     3961 agccgaagag atacgaagat tctggttcat acttacttgt tcgatcattt caggcagacg
     4021 ttccaaccgt tgtttagtca ctgcagaaac aaaaacgatt ggagcgtaat caagataccg
     4081 gaattcatca cgaatctctt gttcgaaatc acgcattgta ttggtttctt tctttacaag
     4141 atcccattta ttcacgacga taataattcc acgaccagct tcatgggcgt aacccgctac
     4201 tcgcttgtct tgttcccgaa tcccttcttc agcattcagt accatcaaaa cgatatcaga
     4261 acggtcaatg gcacgcattg cacgcatcac gctgtatttt tcagtatttt cgtatacttt
     4321 tccgcgttta cgcataccag ctgtatctat cattaagaat ttctgaccac tttcagaaac
     4381 gaagtgggtg tcgattgcgt ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc
     4441 ttctcctaaa atcgcattga tcaaagagga tttaccaaca tttgggcgac caatcaaact
     4501 aaacttaatc gtgtcgtcgt cctcttcttc agtctcttca gagaaatact tcactgcttc
     4561 atctaaaata tcaccaatcc ctagtccatg gcttcctgaa acaggataag gatcgcctag
     4621 ccctaaggaa taaaattcat agatatcgtt tctcatttct ggattatcta ctttattgac
     4681 tgctaaaatc actggtttat tacttctgta taaaattttc gcaaccatct catctgcgtc
     4741 tgtcacgcct tcgcgtccgc tgactacaca aatgattaca tctgcttctt caatcgcgat
     4801 ttctgcttga tgcttgatct gatccataaa aggttcatcg ccaagatcaa ttccgcctgt
     4861 gtcgatcacg ctgaattctc gacctaacca ttcacctttt gcataaatac gatcacgagt
     4921 tactccagga gtatcttcga caatcgagat acgctcacca gcgatgcggt taaaaatcgt
     4981 agacttaccg acgttcgggc ggccaacgat tgcaattgtt ggatttgcca tattatttcc
     5041 tcctcacaag tttccaatct cacttagttt aacgaatgca ttgccaactt tcaagcatag
     5101 attgtcaatt aaacgaagta tttttattcc ttattgaaat actaatcgct tttcaaaaga
     5161 aaaactgaga caaaagcagc tgctttcatc tcagtcacag atacaaaatc aattattttt
     5221 cagaatcatc ggttgctttt tcttctactt cttctttcaa cgcatcacct aaaatgcctc
     5281 ccatagtaaa tccagtattt tcttctggta attcataaga ctcaacattt tttggttctt
     5341 cttctgaagc tggtttttct tctaaagctt tgatactcaa tgcaatacga tgttcttctg
     5401 gatggatctc taatactttc actttcactt cgtcaccttc atgaagcact tcatgtggtg
     5461 tcgcaatatg tttatgtgaa atttgagaga tatggactag cccttctact ccagggaaca
     5521 cttcaacaaa ggcaccgaag cttgtcaaac gtttaactgt tccgtctaat actgtgccaa
     5581 ctggagcttt tgtatcgatt tctgaccaag gtccaggctg tgtgtctttg attgacaagg
     5641 aaacacgttc ttgttcagga ttgatagaca acactttgac atttacatca tcattgacag
     5701 ccaatacatc acttggtttt gctacatgac tatgtgaaat ctctgagaca tggactagac
     5761 cgtcaattcc gcctaggtcg acaaatgcgc caaaatcagt aagacgtgca acacgtccac
     5821 tgagaacatc tccctcatgg atagttgaaa gaatttcttt tttcttttct tctctttcgt
     5881 tttcgactac cgctttatgc gataagatca aacgattttc tgatggttcg atttcgatga
     5941 ttttaaagct caatgttttg cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca
     6001 ccattgatgc agggacaaaa ccacgtacac cgacgtcaac gactaaaccg cctttgacaa
     6061 catttgtaac aggtgcttcg atgaccttgc cctcttggaa atctctttcg atatcttccc
     6121 aaactttttt agcatctaaa cggcgttttg aaagtagata gctgccgttt tctttatctt
     6181 tgccgatcgt actgataacg actaaatcta atacatcacc gacttttact acttcgctga
     6241 tatcttctac cggcaaagtt gataattctt ttgccggaac gactccttca actccagccc
     6301 cttcgattcc gacaatcact tgtttgtctt caatgactaa aacttcgccc ttaacaacat
     6361 cgccaacttt tacttcttgt acgcttttca ttgcgtcttc cattgactgg ttgttctctt
     6421 gattttgatc aaattctgtc ataacacttg tcctcctaac caacattctg ccgtaagtac
     6481 ggtactgttt ttagtttaat tgattattca aaaaaaataa agcgatttcg ttcgttttcc
     6541 ttgaaaaaac aattgttttt catttttttt cttaatttaa aaaagaagat aacctttttt
     6601 caaaacaaca gcttttattg ctgcaacgac ttctggaatc gatttgccag tcgtatcgat
     6661 acgaacagca tcctctgctt gcttcagcgg agagacgtcc cttgttgaat cataatggtc
     6721 tctttcctgt atctctttcg tcagtgtttc aagatcagtc ggaattcctt tttcttggtt
     6781 ctctttgaaa cgtctttctg cacgctcact tacgcttgct actaaaaaga ttttcacttc
     6841 tgcattcggt aatacagctg tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc
     6901 ccctattttt cgttggacag caactaattc ttctctgact tttccatgtg cagagacttc
     6961 agaaacagct tttgtgacat ctggttgacg gatttctaaa gtcacatctt ttgatgctat
     7021 gaatacatgc tgtccatctt cttgttgcga aaaagagata ggatactttt tgatcagcga
     7081 aactagccct tcttcatctg aaaaagatac attgttcgta atagctaaat aagttactgc
     7141 gcgatacatg gcaccggtat ctgtataaat ataattcaat tcttttgcta atatcttggc
     7201 aacggtactt ttcccagatg aagcaggccc gtcgattgca atactgattt gtgtcatgat
     7261 ataactcctt tttctcagaa aaaaagccgc aaagcgcggc tattattatt taattcttaa
     7321 ttcttgacca gggtaaagca taaagttgtt tggatctaag ccattcaatt caaacaattg
     7381 atcagtggtg atccctgcac gctcagccac ttgttttgga ccttcgcctg cttgaacagt
     7441 cgttgttgaa ccggctgcag ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga
     7501 atcccctgct tgataagttg cctcacttga ggaagtcggt gttgtctctg ctgcaatact
     7561 gctttctgac gttacacctg tatcttgaga cacagtagat tcttccgcga ttgtactaga
     7621 ttctactgtt gaagtctcag ttgactcctc ttttgttgta cttgtagaac tttctactac
     7681 tgatgtcgaa gtttcagaag aagttgctgc tgttgcattg ttgcttgatc catttctgat
     7741 ccagaaataa gcacctgctg gaatagcgat acataagacc agtaaaatca aaaatagcga
     7801 aagaaataat gtatttcctt tcttttgttg tctctgagaa cttcttgatg aaacttcatc
     7861 atctgtatcg tagattggtt gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg
     7921 atgtctatct tttctgctca ctgttttacc tcctaaactc tatcgtgtgt attataccat
     7981 aggaaaaagt gtcttgtcct aaaaaatcaa tgttccatgt tttttttaaa taaatttagt
     8041 aaaatcgttt cccaatgaag ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt
     8101 tctgcttttg ctccatcaat atcacaacaa ttctgcggct tttcggagag tttttcgcca
     8161 aaataagcta agatgaattt tctgcggcag ttttcttcat taatatagcg aagcatctgc
     8221 tgcaggcgga attctttttc tttttcctga cgtttgagcc gttccaccca attttctggt
     8281 ttttcagact gctggatcag ctccatccat tttttttgca gctcatcaaa gggagcttgc
     8341 tctgtggcat attccaaata aagctcaaaa ctttgtcgct gttctctaga aagttgatta
     8401 aagaaataat ggatacgttc atccccactt tgataaaaaa gaattgctgc actttcttcc
     8461 tgatctctgc ctgctcgacc gatttcttgt acatagtttt ctagactgtc tggcaaatca
     8521 taatggacca cataacggat atcagattta tcgatcccca taccaaatgc attcgtagca
     8581 atgagaaact gcagctgatt ttttacaaac tgctgttgaa gttgtcttct ttgagctgca
     8641 tcaagaccac cgtgatagta tccaactgta aaacgttccc tgaataaatg atacaatcgt
     8701 tcgacttctt tttttgttgc acaataaatg attgccgctc cttgtgctct ttccatgaag
     8761 tgttcaagtt cttgttcttt ttgctgcgtt ttccgaacaa aaagcgagat attttgccga
     8821 ttgactgatt gtctgatctc ttttggtggt cgatcaaata gtacatgacg tatatctctt
     8881 gctactaaat ctgttgctgt cgccgttagt gccagtgtga ccgggtttcc taaaagcttt
     8941 cggatttttc ctaactgttg atattctgga cggaaatcaa ctccccattg agacacgcaa
     9001 tgagcctcat ctactacata taacgcaata ttttgttttt tcagatgctc taaaagagaa
     9061 ggattagtca acatttcggg actcaaaaac aaaaatttat attgcgatag atgacggagg
     9121 acgtatcttc tttcagattg cgaaagtaaa ctattgaaag cagctactcg tttctcccct
     9181 cgtttttgta attgcgtcac ttgatcttcc attagagaaa gcagcggtga cacgatgatg
     9241 accagacctt ccattaaata ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta
     9301 ggcaaaatag cgagagtatc ttctccatca agcaacgcct gaataatttc ttcttggccg
     9361 ggacgaaatg aatcaaatcc aaaatatttt tttaattcat ttattaacat tctgtatcgc
     9421 ttcctttctc aatagataga tttgatacaa acgaaattct ccataatcta attgtccatc
     9481 tacattccat tcgctaaagc gccactctcg cacggaatcc ttatttggtt ccaaacgttc
     9541 gattgtttct gcagagagaa tccactcgta tggaaaatca tcaaaaaaca aggcccactc
     9601 aataagatga tctgttactg ttcctctttt taaatgacgg attgccatga tctggtcaat
     9661 tgtctgacca ttcataaaca tctgcttggt gatcatcatg ctttgattga aattttgctg
     9721 taataatgaa tcgatcaaag cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa
     9781 caaaaggtgg atacatctgc tttgttgcag ataaaccgct gactcatcat tgttttttgc
     9841 cagctgataa ggaagcagcc ctgttcgctc atttccagat aattggttag ctaaaaaatc
     9901 tgctgcttct tctggtatct ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat
     9961 caaaatttca cgtggcaatt ggctttcact aagccatttt tttagttgga aagtataaaa
    10021 aggacttgtc tctgctggaa gatagtcttg aatacccgtt gccagattag aaattacttg
    10081 aacagcaaat ttaatgagcc gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg
    10141 caaaccagta tgttctattt gatgttcgga caacatatca gcccctgcag gcgttagctt
    10201 tgcttcattt tcatttattt cgatccaacc ttgctgcgca attttttgca aaatttgata
    10261 aaacttatcc tgcttcaatt ctggaaaact gttatggata aacaaaagtt cgtgggtaaa
    10321 tccataaata agtactgaag tcgttcgttt tcccacaagg agttggtaaa gagaactaat
    10381 ccgcagcttg tgtcctgatg aaaatagcga taaaataaaa acaatcatat tattctcctt
    10441 aagttaggat ggttagaaat gtcactacta tgtaaacttg tacctgaacg ctgtattgca
    10501 tgcggtcttt gtcaaatcga agcgccagat attttcgatt atgatgaaga aggaatcgtt
    10561 ttatttgccc aagaaccaga ggctcatcaa cagttcgtga tgccggaaga agaaacatat
    10621 gtaaaaaaag cgtatcaaaa atgtccagtt cgagcgattt tattagaaaa taaaatataa
    10681 atataaacga aactttaaaa acgtacacta agttctctaa acttgaaaat aagccgggat
    10741 ctgtttctct tgttccgtga aatcccgact tattttgaaa gattcatttg ctatctatag
    10801 ttaattgact agttttttca cggaccctat aggacccatt tatattattt caactttttc
    10861 agccagtttt ccaatgtatt gacgatcaca gtttgctggt ctgcgttaga aatttctgcc
    10921 tctccatctc ctttttgctc accatagctg ccaaaacctc catgatttcc gccattgatt
    10981 gatacatact ctgttctttc cggtaaatac tgcttagctt cttgataagc ttcctgattc
    11041 aatactttat cttttgtcgc cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt
    11101 ccttttttgt cgggataact tgccatgaag aatacccctt ttaaatgttt gtctgaatga
    11161 ttcttattga cataacgact tgccattacg ccacctaatg aatggccacc gatcacataa
    11221 tcggaatttg gaaaatcttc tttgacctta tccgctttgt ttccgcccat cactgctaga
    11281 tcaagtggca ttttgacaat agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa
    11341 atactataac tttctggctc tacgagagca ccaggataaa aaataagtaa tggagacttt
    11401 ccatgattct ttttctctcc ttcaaaaaat aagtaatctt ctttgttttt tccttctttt
    11461 accaacactt gcgcttctga cgatggttcg tacgtatttt gctgtatata gtaataaccg
    11521 gctccaccga gtaatcctaa aatgatgact aagccaatta gtattcgtct aaatattttc
    11581 actttctccc accttttcta tctgagtgac ccctttttct taatcaagta tgattatacc
    11641 ttaaaaaaat aagagagaaa tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc
    11701 catttgaata tccgcccttt ttgtatgttt atttttattt agcacataaa cgatacacag
    11761 cttctgcata aatttccatt gctttataca tactacttaa ttcccatcgt tcattcgcct
    11821 ggtgcataaa gtcaggagta tcagggaaca tcgcaccgaa tgccacacac tggttcatcg
    11881 tacgagcaaa agtagcgccg cctgatacaa acggttcagt catgtctcca gtaatatcgc
    11941 gatatgtccc caatagattt ttcactaact cactgtctag tggcacgtat aatgaatcaa
    12001 ggaagtcaaa ttcttcataa gtcaacccat atttttctgc tgttttagtt aatttagcta
    12061 ctaaatcatc tttcttgaat gtaacaggga ttctcatatc tacaccgatt tttgtttgtt
    12121 ctggtgtgat ttccaaactt gcaaagttca tcgttagctc gccggattgt tcatcttctg
    12181 ttttgcccac gacagcttca ccagttgcat tttcttgaac taattttcct aagaaattga
    12241 ttgggccaaa atcaaatact tctgaaagag caattgccag acgagaaata gcattcactc
    12301 cttgtgctgc atctttcgcg tggatacttt taccaagaac gacgatgcct tcaccttgtt
    12361 cttcgaaatc gaattcgtgt tttttcaatg cttcttttac ttcagaaagc ttttctccag
    12421 agtaaggagc tgcatcagga acaacattca acgctcctcc agcttttaca gaaaactcgt
    12481 tcgttcctgg tcctgtcaag taagcttgca ataagccttt ttctgcataa attaaaggaa
    12541 attcagcatc tggcgcaaat ccttgcgtaa ttccttcttc tttttcgtta tatttttcta
    12601 aacaacgcca taaattttct tcatctgtac caaagataaa acgaatacgt gtcttgaatt
    12661 ccacgccagc atcaatcaaa gctttgacgg catacattgc cgcaatagaa ggacctttgt
    12721 catcttggga tccgcgacca actaaccagc cgtcttttat agttggatcg aatggttttg
    12781 tttcccaatt attttcgtcc cctgctggaa caacgtccat atgacacaag ataccgaata
    12841 attcatctcc agagccaatc tctgaataac cgtaatagcc ttctggatct ttaaatgttc
    12901 taaatcctag cttttcactg atttccaata ctttatccaa agcttcaatc acttttttac
    12961 cgaagggatg tccttgtcct gaatctgctt catctagtac ggaaggaatt cggatcaatt
    13021 cgctcaatga ttctaatgct tgttcatgat gttgttctgt cacaaatttt ttcatgatat
    13081 tatcctccta atatgttaaa aagggtcatg tcaaattcct ccgacacaac ctcttcttct
    13141 caaataatga cgttttaagc ctgctccatc agcaagcaga atgttcttaa caaatgatga
    13201 aagaaaaaac actcactgaa tggagctatt gacttatcca cgtgcttatc gatagccgtt
    13261 tatcggtttc ttcattctta tgatagacct tgtacctgta tttgtctagg tttagaacat
    13321 tgctgctaca cctaggatca cacagatggc tacaaataat atcgcaatta atttaccggt
    13381 aaatttccac cacactgaaa catcgaaacg agcaattgct acagcaccca ttacgatagc
    13441 agatgttggt gtaattaagt ttactaaacc agatgcagat tgataagcag tgattactaa
    13501 atccttaccg acgccggcaa attcacccat aggtcccatg attcccattg ttgcagcagc
    13561 taagccggaa gttgaaggaa tcaagaatga catagggata tagaaaataa atgtaataat
    13621 gatgaataca cttgaagata atgaacttaa tccttgttcg ccccaatgta agatggtgtc
    13681 tgtgattaat ccattgttca taaccacttg gataccacga gcaacagcta ctacgattgc
    13741 tacaccgatc aaatcagaag caccagctaa aaattcagag acaaattcag actctttcat
    13801 gccataagtg attgctacta cgatggacat tactaagaat aacatagtaa tttctgggaa
    13861 gtaccagtca cctaatggaa gcatgctttt acctagaacc gtacctagta ccggaaggtt
    13921 tgttaaccag tttgtcaatg attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg
    13981 aatcaaactg atgatcatga taccaaaagt aataaagaac aatacattaa catgtttttg
    14041 ttttttcgtg attacttctt gacgaccgat tgcttcaata tcgaaatgct tcatatcttc
    14101 tttacgttgg ttgtatacta atgattttgt tggatctttt tcgatctttg atgcataacg
    14161 atacacatat acaatagaaa tagctaacaa aataacgaac atcaagaatc gaagaccaat
    14221 accttcaccc atcgaaatcc caacagcttg tgaagctacg cctgttgcaa aaggatttac
    14281 cgttgaagct agacagccta cttgagaccc tactaatacg attgctacag ctactactgt
    14341 atcaaagcct acagccatca tgactgggat cagtaaagca tagaatggaa tcgtttcttc
    14401 tgccattccg taagtagagc cgcctaatgc aaataacagc atcaatactg gaataagcat
    14461 tttttctttt cctttgaatt tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt
    14521 tttgttgata atacctaaaa atccaccaac aaccaaaatg aagaaagaga ttgggattgc
    14581 agcaggtgtt tctttagtta gctcccccgc tggtacacct agcatcccat tgattggcgc
    14641 catgaaaata tcccacagcc cttgaggatt ttgttgtact cgttcatatg atccagcgac
    14701 gatgttgcct gcatcgtcta cactatagtg cccagctggt ataaaccaag taagtacagc
    14761 gattactgca ataataataa ataagaccgt atacgctgaa ggcatttgaa attttttctt
    14821 ttttgtttgt tccatcttct tcttcctttc ttttccgtta gagacaacaa ttttggctct
    14881 aatgttattt tatcaaaaag agtatcagaa caaaaataat aacacgcatt ttgtaaaact
    14941 tttgttcaaa aagttcgttt ttccctattc cctcctcttt tttcaggttt ttaaagcttt
    15001 cttctttttc attgtagcgt ttcctttttt ttataaacaa acattttcgt cttttaaaag
    15061 gagaagaatt tcacatttgc aaagaattga ttgattttta tgcataaatc aaaaaaatac
    15121 tcaaaacaaa caaataaaac gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa
    15181 aagaccaaga aatttcttga tctttttgat atttatttga ctgctgtatg acgttgttcg
    15241 aactgatgtt gttttcgact taaccatgga agaagttgcg catgcagcac taaaaagaca
    15301 gcactcacga tgaatccttt gatcaagttg aaaggaacga tcccaatcag tacatagttt
    15361 gctaaagaca tgcccagcat ctgtgttgcg ttcagcccta aaaacattaa gtaaagaggc
    15421 gtaataacga aataatttgc gatactcata aaaatagtta gagcgatggt tcctgtaatg
    15481 acacctaaaa atttgtttct tcctttatgc tgtttcttta cactaaagaa ataataaatc
    15541 gggaatgtaa agatcgttgt tgataagaaa ctagcagtgt ctcctaccaa attatccgga
    15601 gaaaaacctg tagtcagcag atgtaatact gaacgcaaga acgctgttgc aactccggcc
    15661 gctggaccga ataagaacat gctgatcaat accgagatat cactaaaatc gatcttcaaa
    15721 aaactaaaag ccggcatgat cggaaaagca aaatactgta aaactaatgc gatcgcagca
    15781 aacatcgcta ctgcaaccat tttctgtaca cgggtgttct tcatttgaaa tcctcctgtt
    15841 aggactcctc ttcagcgaac tttttgacgt ttctctccaa atgaaaaaac tctattttcc
    15901 agggaaaata gagttagagt tatttgatca agcgtcgtca aataagctct atcttcttta
    15961 tccagactat actgtcggta tcggaatttc accgattcag ctattttttt gcaaaatagg
    16021 tcgtggacta taaccaccgg tcgggaattt caccctgccc ctgaagacga accttatata
    16081 atttttgttt acatattcat tatacatatc tattcaaaaa acgcaacatc taacacttat
    16141 aaaaagtaag tgttcatttt gagtggttca gcaaactgct gacttctttt ttgttcagtt
    16201 cacggtaatc cccaggacgt aggccttgta aagtcagatc tccgtatttt tcacgtttta
    16261 gtttttgcac aggaagacca actgcttgaa gcatattttt cacttgatga ttacgtcctt
    16321 cgtggatcgt caattccacg atactgtggt ttgtcttagg atccactgat aaaatttgga
    16381 atttagctgg agatgttttt cgtccttcga tctttattcc ttttgtcaaa ggtgcaagca
    16441 tcgattttgt agcgatccct tttacctttg caacgtaaac tttatccact tcatgttttg
    16501 gatgtgtcag gcgctgagca aaatctccat catttgtcag tagcaagatc cccgaagtat
    16561 cgtaatccag tcgacctaca ggatagatac gttcttttac catcggcaaa agatccgtaa
    16621 caacttttct tcctttgtca tctgcaacag cagaaataac tcctttaggt ttgtacaata
    16681 aatagtaacc gtattcttct tgataaattg ggacttcatc cacttccaca gtgtcatgtt
    16741 tcccaacttt tatccctaat tcccttacaa cttgtccgtt tacttttaca cgtcctgcaa
    16801 ggatgaattc ttctgctttt cgacgagaag tgatgccagc gtgggcaatt actttctgca
    16861 atctctccat tacaattatt ctcctttatt cattccatca aagaatagat ctggtgacac
    16921 gtcttcttca agtgaaattt ccatttcttg tgtatcaggc agttcttcta atgatttcaa
    16981 accaaaataa tctaagaagt agccagttgt tccatataat atcggccgac ctggtccttc
    17041 tactctacct ttttcttcaa tcagtttatg ggcagctaga cgctgtaccg ctcctgaaac
    17101 ctgaactcct cgaatctgct cgatttcagc tcttgtgatt ggctgtttat aagcgatgat
    17161 tgctaaggtt tcgacggcgg cttgagataa tgtgtttgat gtcccttgcg catatcgctt
    17221 aagtaaggga gccagctctt ttttagtcgt taatacataa tggctttccg tttcaaaaat
    17281 atgcaaagct gagtgcgagt tttgagtgta agattctttt aattctttca ctaaacttgt
    17341 gacttctgct tcgctgagat ttaacagtcc gcttaattct tcattactga tcccttcctc
    17401 gccaacaata aaaagaaggg cttcaagttc acttaatttc gtcatgttcg gtatctccta
    17461 ctgctggata aagcataatt gattcatagt tttctttttg ttgcgcaatg atctgccctt
    17521 ttttcatcaa ttctagcaaa gccataaaag tagtgacaac ttcactttta gaaggtgact
    17581 caaaaaaaga atcgaaagta cagccatgcg catttctttt tatacgctct tcgataaata
    17641 ccattcgttc ttcgatcgtt gtgtcatcgg gcgtgatcgt tttttccact ttttgagaaa
    17701 atttcttacg ttctaagatt ttctgcatgg cacggatcaa atcgattttt ttgacttgtc
    17761 ctcgcttcaa cggcttttca gcatccgcta acccatcgat gttcataggt tcttttgtgt
    17821 aataaagact tcgttcctct gctttttctg tcagtctttc agctgcatat ttatatttac
    17881 ggtattctaa aagctgagtg accaattctt ctcgaggatc ttcttcccat aattcttcat
    17941 cgtctgtgac gaattcttgg acaggaagca atgtcttgct tttgattgcc atcaatgtag
    18001 cagccatcac taagtattct cctgcaacag ctagctcgag tgttttcatt gtatggatat
    18061 aattcatata ttgctccgtg atcgtagcga tcggtatatc atatatatcg atttccattt
    18121 gctgaatcag atgaagcagc agatcgagag gaccctcgaa tacatctaat ttaatattga
    18181 tctccgtcaa ctcattcact ctttcttctt tttctttgct agccattttc caatgtaagg
    18241 ctctgtgatt tcagttgcac ggatggagac atccgggtac ttttcctgta attcatctaa
    18301 catttgaaag cccatattct caccgcgata agacggattc aaagaaatgt catggatgat
    18361 cagctgatcg ttcgttgccc agtaaatacc aataatccct tgaatgttgg ttgaaccttc
    18421 tggcgtaaag aaaaaaagtt cataatcgtc ttcagattcg tacgtatcaa tctccttcaa
    18481 caaagaagtt ttacctgtca gtttcttatg gaaactcaat agtcccatag caattttacg
    18541 gttttctttc cggtaatgtg ttaacatctt ctcaccttcc tatgactaag cccttggaaa
    18601 atgctgctta taaacatccg tcattctttt cttcgtgata tgtgtataaa tctgagtcgt
    18661 agagatatcc gcgtgaccta acaattcctg tactgtccgc aaatcagctc cattttctag
    18721 cagatgtgtg gcaaagctat gccgcagcgt atgtggtgtt acttctttgt aaatcccagc
    18781 ctctcgtact aactgcttca gatttttcca gattccttgc cgagaaagac ctttcccatg
    18841 attattgaca aatacatgca tttcagatgc gtcctttaca agtaatggac gtgcttcgtc
    18901 taagtagcgt tccagccatt ggatcgcata atcacctaaa ggaatgatcc gctctttatc
    18961 tccttttcca actgtctgta ccagtccaag agaaagatga agatctccca atttcaatcc
    19021 aatcaattca ctgacgcgca tcccagtagc atacatgact tccaagattg cacgatctct
    19081 tatccctaac gtttttgtcg tatcaggtgc ttcaatcagc ttttctactt ctgtcagagt
    19141 caatgtactt ggtaatttct gtgctttctt cggcgtatcg atatgttgca tcggatcatg
    19201 atcagtgata cgctcttgcc gtaaaaactg atggaatctt ctgagacttg agatcatccg
    19261 agtaacagtt gctgtcgctt ttttttcttc atgcaacttc tccagaaaac ggatgactaa
    19321 aaagcgatcg acatcctgcc atgaagcaat tttctgctcc tgtagaaaat gcaagtactg
    19381 ttccaaatca cgttcatagc tttgtcgtgt attggcggac aatccccgtt caatattcaa
    19441 gtagtggaga taatcgttga tttgctcttt cataataatc cccctcatgc ctctctatca
    19501 tatcagatac cgcttcattc tgatagtctt tttccataat ctgagcaaag aaaaagccgt
    19561 ctagacactc agacggactg gtttcttttt tctttttcat agcattcctg acagattcca
    19621 tggaacgtta gccgatgatc ttttactaaa aaatgataac gttcttctac tacttgctcc
    19681 acttcaagta aaagatcctc ttctacttcc tcgatcgtgc cgcagttcaa gcatagtaaa
    19741 tgatgatgga aatgtttggc gccttctttt ctcaaatcat aacgggctaa tccatcatta
    19801 aaacttactt tatcgacaat tttcaattct gtcaagattt caagggttcg ataaacagta
    19861 gcaagtccaa tttccggact cttttttttc actaaaaaga agatttcttc tgcagataaa
    19921 tgctctttct cattttccaa aagcacaagc agagtagctt ctctttgcgg tgtcagctta
    19981 aaccccgctt catgtagctg ctgttttgtt tttttcatcg ccgaaatagc attcatgacc
    20041 atttactcaa ccccaacaat ttataataat tacaaataaa aaaagatata acactatgtt
    20101 aattaaaatt attataagct agttaagaaa aacatgcaag ggattctcaa ttagattttt
    20161 tgactagttt tgtcacaccg ttttcttgtg taatcaatcc ttgtttcaaa agattaccta
    20221 atgcgcgctt aaatgctcct ttgctgatac caaaagcttt catgatttct tctggatccg
    20281 atttatctgt aaagttgatt tgctgatctg cagaacgttc taaaatggtt aaaatcattt
    20341 gtgcatcatc tgatatagct tcatatgctc ttggcttcaa tgaaagattc agtacaccgt
    20401 ctggtcggac accaatcact cgacctttta tctgctcgcc tagacgaggt tcattatatc
    20461 gttcagaagg atggataaac ccaagataga aatcttccgt taaaacgtac gtacctgtta
    20521 atttcaagcg gtatgctgtt cctatcacat ctttgttttt catttcttct gttccatatt
    20581 tgcttaaaga tttgaatatt ttttcatctg ctaaactgcc ccaaatacgg tcttttgcat
    20641 caactctaag ggaaatcatc aagcgatccc cttttttagg ccatagctct gtcattgtcg
    20701 gcaattcatc aagagatacg acaaagtctt tatctggaag accgatatcg acaaacgcac
    20761 ctaaatcttt tcgtgtagca gtaacgattc caaaaccgta atgaccgata cggcttttag
    20821 gaatttgtgt agtgatccga ttttcatgtt tttgattttg gtaaccgaat ccttcaactg
    20881 cttcaccgat tttgtgttca ccttctgatt tgcttaagcc aaaggtttgt ccgttttttt
    20941 ggacaaagta gtttttttca ttttcatcaa taataatacc tgtaaatata gttgctaata
    21001 aatcgttcat ttttttctcc ctctatagtg aaaggttttc ttaatacatt tctttgctat
    21061 cataacataa tgttatctac ttgaatagct gagccttggt ttggaaaggt gaaaaaagga
    21121 gtatgacaac agttgtgtca tactcccctt tttcgaataa acggtgttaa acggcaggct
    21181 cacagcctct ttcatttgcc taaaattaat tgctcccatt tcctccgaac catccagttt
    21241 tacagttgat ggttacgatg taaaatggca aagcactttc tccaatgcct ttcatcaatg
    21301 cagattttgt tgaagtggca tatagattat aatagccttc cccattttcg attctggctt
    21361 tttctaatct gtaacctcct tcaacgatat atccacgttg gatacatgta gcaatcactt
    21421 tgctttggac acctggtgcc cacgtccatg ctggattaga tgcatcggca atatcacttg
    21481 ctctggcaga tttgattggc tgattcgctg agtttgaaga ggaaggggtc gaggatgccg
    21541 cttcttgctg tgctgcttgt gcgaccgcag cttgttgagc ggcttgagct gcagctgctg
    21601 cttgagcggc ttgttttgct tgttcttcag ctgctttttt cgcttcttct gcttttttct
    21661 tttcctcttc ttcttttttc tctttatcag tgagcatctt atctacttgt ttcaattgtt
    21721 cattcaactg agcagataga tctgtatttt tcactttttc tactgcttct tttgccgtct
    21781 tgtattggtc gcgtgttgct gaatccacta cttttccgtc tttaaagact atagctgttt
    21841 tttctttagc tgtttgcaat tcagcatatt gatttttagc ttctgtttgt gcttgttgaa
    21901 tcaattttcc aaaatctgtg ttatccgttt cgattgcttg gatctcttta tctgctttca
    21961 acttgatgtc atctgctaga tgatcatcga cgatggcagg tgctatgaac cactcattca
    22021 ctttttggat atctcggatc ttagattgga tatcttggta agttgtttct aactctgaat
    22081 atcctttttc attcttaaga ctggataaat cattttttag ttttgataaa tcttgatgaa
    22141 tcatatctgc acgaataaat tgatggtgat catctgtata aaaggcagca agtttctcat
    22201 gaagttcttc catttgttgc tgtctttttg cttctgctgc tacttcggct tctacttttt
    22261 gatgatggtc ataataagcc cagcttcctc caccgagtag aagtactgct gctaaaacga
    22321 gataaggtac tttttttgat tttttctttt gcgctttatc tggatctgtt ttttctaagt
    22381 ttgattcttg atgtgttttt tcagtatctg gcacgattgt tattgatttc gcttctgctt
    22441 caaacagctt aggctggttc tcttcttttt ctatttttgc ttcaagatca gtaccctctt
    22501 tgcttacaga ttgattttca gcatcggatt cactatttat ttcatcgggc tctgttgact
    22561 ttttgtctgt gttttcgagt atttcttttt tctctgcttc cggcagttta ttcgtttttt
    22621 ccttttctaa ttgtttttca gtaaatactt cagttttttc tgtgatatcc gtttttacgt
    22681 cttttatttt tactgtttct ttacctgtgg cgttttctct atcagagtct ttttcagttt
    22741 cttgttcctt ttctggctct actttgtttt cctgtgcaat tttttcactg atcattttga
    22801 gcagctcttt cgcgtgctct tcttttgtat cttcacgatg tgctttgata taagcggata
    22861 gtatcgaatt ttcttcctca ttatcgacga tttctttcag ttcagctact cttctttttt
    22921 gttttgattc aagcgtttct tcttgattct ttcctgattc ttccgaagtc tcatgaacag
    22981 ttgctttctt ctgttcattt ttctctatat tagttacttg atcgtgagca ggtggttctt
    23041 cgtcttctgg ttctgctttt tcgaataatt ccattacaga ttctagaggt aaatctttca
    23101 attccgacca ttcgattgga tcgtttaatt ctgtatcagg aaagactgca tcttcagttg
    23161 atttatcctg catagctgca tctgtatttg tttcttcaat tgattctttt atttgctgat
    23221 cttctgcagt tatttgatga ccgcagtctg gacagatagt attctgctcc atttttttcg
    23281 atccgcaatt tggacatttt ttcatcactt agcgatcggc tcctttacta ggtttacgct
    23341 accatttaat ctatcatatt ctatacgtca cgccaatagc ttatttttag gatttactta
    23401 aaaataatga atgaatttcc ttcctataga aaaaaaagct tgagactgcg tagtctcaag
    23461 c
//
LOCUS       DBGZHO010000043        22321 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.043, whole genome shotgun sequence.
ACCESSION   DBGZHO010000043 DBGZHO010000000
VERSION     DBGZHO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.043"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            2..400
                     /locus_tag="ACN3HL_001866"
     CDS             2..400
                     /locus_tag="ACN3HL_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HHC8006724.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="ACN3HL_001867"
     CDS             384..1079
                     /locus_tag="ACN3HL_001867"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HHC8006725.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1673..2560)
                     /locus_tag="ACN3HL_001868"
     CDS             complement(1673..2560)
                     /locus_tag="ACN3HL_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HHC8006726.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2745..3584
                     /locus_tag="ACN3HL_001869"
     CDS             2745..3584
                     /locus_tag="ACN3HL_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HHC8006727.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3780..4754
                     /gene="sgrA"
                     /locus_tag="ACN3HL_001870"
     CDS             3780..4754
                     /gene="sgrA"
                     /locus_tag="ACN3HL_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HHC8006728.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5052..5408
                     /locus_tag="ACN3HL_001871"
     CDS             5052..5408
                     /locus_tag="ACN3HL_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006729.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5453..6568
                     /locus_tag="ACN3HL_001872"
     CDS             5453..6568
                     /locus_tag="ACN3HL_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006730.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6594..7034)
                     /locus_tag="ACN3HL_001873"
     CDS             complement(6594..7034)
                     /locus_tag="ACN3HL_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HHC8006731.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7194..7700
                     /locus_tag="ACN3HL_001874"
     CDS             7194..7700
                     /locus_tag="ACN3HL_001874"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HHC8006732.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7868..9780
                     /locus_tag="ACN3HL_001875"
                     /pseudo
     CDS             7868..9780
                     /locus_tag="ACN3HL_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            9785..10786
                     /locus_tag="ACN3HL_001876"
     CDS             9785..10786
                     /locus_tag="ACN3HL_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8006733.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10988..11194)
                     /locus_tag="ACN3HL_001877"
     CDS             complement(10988..11194)
                     /locus_tag="ACN3HL_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HHC8006734.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11840..12688)
                     /locus_tag="ACN3HL_001878"
     CDS             complement(11840..12688)
                     /locus_tag="ACN3HL_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHC8006735.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12852..13754
                     /gene="gnd"
                     /locus_tag="ACN3HL_001879"
     CDS             12852..13754
                     /gene="gnd"
                     /locus_tag="ACN3HL_001879"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HHC8006736.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13756..14757
                     /locus_tag="ACN3HL_001880"
     CDS             13756..14757
                     /locus_tag="ACN3HL_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HHC8006737.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14754..15038
                     /locus_tag="ACN3HL_001881"
     CDS             14754..15038
                     /locus_tag="ACN3HL_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HHC8006738.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15071..15868
                     /locus_tag="ACN3HL_001882"
     CDS             15071..15868
                     /locus_tag="ACN3HL_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HHC8006739.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15882..16715
                     /locus_tag="ACN3HL_001883"
     CDS             15882..16715
                     /locus_tag="ACN3HL_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHC8006740.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16733..17590
                     /locus_tag="ACN3HL_001884"
     CDS             16733..17590
                     /locus_tag="ACN3HL_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8006741.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17612..18121
                     /locus_tag="ACN3HL_001885"
     CDS             17612..18121
                     /locus_tag="ACN3HL_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HHC8006742.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18158..18559
                     /locus_tag="ACN3HL_001886"
     CDS             18158..18559
                     /locus_tag="ACN3HL_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006743.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18671..19024
                     /locus_tag="ACN3HL_001887"
     CDS             18671..19024
                     /locus_tag="ACN3HL_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006744.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19058..19501
                     /locus_tag="ACN3HL_001888"
     CDS             19058..19501
                     /locus_tag="ACN3HL_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8006745.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19518..20603
                     /gene="uxuA"
                     /locus_tag="ACN3HL_001889"
     CDS             19518..20603
                     /gene="uxuA"
                     /locus_tag="ACN3HL_001889"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HHC8006746.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20596..21309
                     /locus_tag="ACN3HL_001890"
     CDS             20596..21309
                     /locus_tag="ACN3HL_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8006747.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21516..21665)
                     /locus_tag="ACN3HL_001891"
     CDS             complement(21516..21665)
                     /locus_tag="ACN3HL_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006748.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22061..22261
                     /locus_tag="ACN3HL_001892"
     CDS             22061..22261
                     /locus_tag="ACN3HL_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8006749.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7686 a         3430 c         4624 g         6581 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat
     1561 aaaaaaaggc cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt
     1621 tccaaaaatc acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga
     1681 atatattttt tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga
     1741 ttgttttatc catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct
     1801 cagatttgta tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat
     1861 aatagctttg ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt
     1921 tttttagttt aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa
     1981 aattcatttt tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct
     2041 tggagaaatt ttctccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg
     2101 aaaatagaat gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat
     2161 ctttatctgt taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa
     2221 agagtttctt atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg
     2281 gaccgagttt tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt
     2341 ttccgtatac atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat
     2401 ttgatttaac ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg
     2461 ttgcaatcgt ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa
     2521 ggcacataat tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag
     2581 tctaacagaa gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt
     2641 agttcgtaaa aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa
     2701 gaaagaaaag ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc
     2761 ggttgattgg atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata
     2821 atgcacttgc ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg
     2881 tcggacattt agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa
     2941 gaatagaaga ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc
     3001 tcgttgttgg aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt
     3061 atcggttaga ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta
     3121 ttgcagtggg ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta
     3181 gatttggtcc gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat
     3241 tgaatcctaa catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca
     3301 gcgcacttat ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga
     3361 attggacaca aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt
     3421 tctccactct gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag
     3481 catctatatc aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat
     3541 ataaaacaaa gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa
     3601 ggctgatatc ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat
     3661 tcaagcgaat acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca
     3721 ttttcatttt atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa
     3781 tgaagaaaac agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga
     3841 ttggaatcag tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa
     3901 ctgatcggat tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca
     3961 aaagcgtgaa tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa
     4021 gttcagaaaa agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg
     4081 agtatacaat aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag
     4141 ttgatttgat tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca
     4201 gttggacagt tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag
     4261 aaaacacgag cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca
     4321 cgagcagcga aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca
     4381 gcgaaagcag tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga
     4441 gtagcacagg aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt
     4501 tggtacctat cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg
     4561 tgctaaaaca gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa
     4621 cagataatag aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta
     4681 catggatggg tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc
     4741 atcgagtgaa ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt
     4801 gagtgaatat ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc
     4861 tatttttgtt tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata
     4921 agagcaagaa taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac
     4981 gaatctattt gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag
     5041 gagtatgtac tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt
     5101 tgaactattg ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc
     5161 taaactacac cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa
     5221 ggtatccaga atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt
     5281 cttctcagtt tttactgagt aaagtttatt ctatactttt agagggaacg attggttata
     5341 ttttactgga ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa
     5401 ttatataagt ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa
     5461 ctatcattta tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat
     5521 ccgatacttt tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt
     5581 atcaagtata aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac
     5641 gcgtagtata gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa
     5701 acaaggccac tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat
     5761 aacaaaagaa gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc
     5821 gatgaatcac atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa
     5881 cacctatttg gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg
     5941 gattgaatcg tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc
     6001 agaaaaaaat tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg
     6061 gacaaaaaag aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat
     6121 atttccagtg atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc
     6181 agagcttaat acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt
     6241 cagggatatt tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg
     6301 taaaacacag gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa
     6361 atatagtgca tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa
     6421 aaaggcatat gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa
     6481 tgattgggcg cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat
     6541 attggaaaaa ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac
     6601 attgcaaaaa gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg
     6661 agctcttgct ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca
     6721 gtcaaaagtt ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta
     6781 cgaatctcaa tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta
     6841 taactaatag aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag
     6901 tggataaatt catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata
     6961 tcatggacga taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac
     7021 aatttaatca tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa
     7081 atagtcgaaa agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa
     7141 ctagctagat aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa
     7201 acacagccga cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc
     7261 cgatacacga attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa
     7321 cgattgggaa accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa
     7381 aaccatggga gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa
     7441 cccatgcgaa ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc
     7501 attcgatcga attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg
     7561 ctcatggatt aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc
     7621 cttttatgaa agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc
     7681 tgacattttt ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt
     7741 tatccattct gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata
     7801 aaccatttat tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata
     7861 aaaaggagtg aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt
     7921 tgctgtaagt acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc
     7981 ggaatctcgg gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag
     8041 tacttcacaa acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga
     8101 tcaagaaacg accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat
     8161 gtcaaacgac gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga
     8221 tgatatcggt aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca
     8281 gatgacagaa atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt
     8341 agtcactgag cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat
     8401 tgctacttat ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct
     8461 tggaggtaca gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa
     8521 acaacttcat caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata
     8581 ttatgtcgat caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg
     8641 gaataacggg atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt
     8701 atttgttgat tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata
     8761 tgagtcagat gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa
     8821 gattttactt tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga
     8881 tattcctgtc aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca
     8941 actacgtttt acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca
     9001 gttagacatc attggggatc aagagcatga agatttattt atgggccttt tgaaacaata
     9061 ctattttgat caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc
     9121 agattcattg cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa
     9181 cgcgcaaaaa ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc
     9241 agggcatgga aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt
     9301 tttgaaagta gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag
     9361 tctactcaaa gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac
     9421 agagcaaaag acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat
     9481 ttttaatgag acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc
     9541 aaaaaagcaa gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga
     9601 tcaatcaagt gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga
     9661 tgcaaaaaaa gaatgttgcc gaaaactgga gaaaagaaac attcgcttct catttattca
     9721 ggtggatttt tatctgttag cacgattatc acatggattt ggcgaagaaa gagagggtaa
     9781 atgaatgaaa tggttcaagc gaatagtgat tgcagtacca gttatcatcg tagttatttt
     9841 agtcactgta tttttgatta atcaaatcac accaaagccg attagcttgc ttgttagaaa
     9901 acaatttgac acaagtgaaa aagaacaagt atatgcccga ccagatgatt tccagcaaaa
     9961 aatcgaacaa atcgatataa aaaaagaaat atcctatcct tcaaagtaca aaaataataa
    10021 tatggatatc tacacaccga aagtggaaaa gaaaaaatta ccgattcttt tctggatgca
    10081 tggaggcgca tatgtaggag gggataaaaa tgattgtcgt gattatttgg aatatctatg
    10141 ttcagacacg cagcaaatca tcgtaaatat agattatgaa cgatcaccgg aagcaaaaca
    10201 tcctacacca gttatccaat tgaacgaagc cattcaagca gctaaaaaag agataaaaga
    10261 tcaagcagat tggtcgaata tttcgattgg tggaaattcg gcaggtgcac aaattagtgg
    10321 agaatatttg ttagcacttc aaaatgaaga aattaaaaaa gctgatcatc ttgatccgac
    10381 tttggagaac aagcagatta cgaagtttat ttctttgtct ggtctgttgg atccttctgc
    10441 acttactcaa gtaagtgata aaatctctag ctttctttat gaaaaatgtg gatgggctta
    10501 ctttgataat aaggactttg aacaatcaga gaaggtcaaa agtttagcct tggtcagaca
    10561 tgcggatcgt tggacgcaaa acacattctt aacggatgga aatacaaata cgtttacgaa
    10621 acaaatggaa gaagtaactt ctgtatttga gaaagcgggg gtgaaagtca caaaagtaga
    10681 ttatgcggag aaaaatgctg ttttgaacca tgaatatcag tttgatttca gcaataaaca
    10741 agcgcaagaa acatatcaaa agttagtaat gtttttcaag gagtaaagtc ttatgatgca
    10801 aaagaggttg taatctgtca cttagctcca agtcacaagg agcaatttca ataaacaagc
    10861 ttttcatggt ttatgaatat tgtaacttgt gactgaggag ttagagatgg caaggggcac
    10921 cttttattcg aaatttggga atatcacacg attattgtca cgatctcttt tacgtaaatt
    10981 ttataagtca gatttgttgt tttgatcgtt taaaaaaagc aacaaatccg aagcctgcgg
    11041 aggcaagaag ggacaaaaag ccgagtggta agcaaaagaa tgctggttcc actaatattc
    11101 cgttgttatt gatataaggc tgggaacaaa gatgaatagc aaataaaatc aatgcactag
    11161 cgaaaaaaag caaagaaata tggatagctt tcataagcag cacctccttt tttataattg
    11221 tatgataaat agattaagaa tctataaatg tgacaagttt gttaggatgt gaataaaatg
    11281 atcatctagc gaacttgaaa caaagatggc taatgataag caattaatga ttcagcaatc
    11341 agataggtac aaagtttacc atcatacgtc tagaccaata atagaaaata tgggaatata
    11401 atagaaaaga tttaggatac ccccaaaaga atttccccaa aaattcgatg tatcctaaac
    11461 ttttttattt tacataacaa tcatatcaac tgtgaaataa aattacaaat gataacctaa
    11521 aatgaggcca aaagccagtg ttatcaagga aatacttaat tcaccaaaat tttttttaat
    11581 tttttagaaa ataagaaaca aaaataataa aaaaaagaaa agataaattt tttactactg
    11641 tatactaact ttgttatcgc atctaacaag taactcgaat aataccaata caaccttctc
    11701 caaagatgcg atgacatacg ttctaaccca ccgactattg atgttctgta ccacccttgc
    11761 agaaccaaaa aagccactac caaatatttg gtagtggctt tttttgtttt atggattttt
    11821 cgctttttct gttatggtgc tattctttga tttcagaaat agtatgtcga actttagcga
    11881 tagaacgacg tgattctttt tcgttgtaaa acatcaaaat cacatataga gagtccaaaa
    11941 tgcttagttg agaaatacgg gaagctaaag cttcagatcg gaattctgtt tcttcagaaa
    12001 tagaaataaa aacgacatcg ccaagtttag caagggaaga attagcttgg ctagtaataa
    12061 cgattgtttt tgctccagtt tttcttacgg tttcagcaat atggattgtt tcttttgatt
    12121 gccctgtgtg agaaatcaaa acagcacagt ctttttccgt caataaagaa gcttccatca
    12181 attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg ggaacgcaaa aatttatgat
    12241 aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa aaaatagaca cgtttagatt
    12301 cattgataat agtagccgct ttttttagat ccttttgttg taacaacttt tttgtgtcat
    12361 ttaaagttga aatactagac tcgaacacct tttgcgccat agtgagctca gtatctgttt
    12421 tctgaatatt ttcgtggata gaaatagcag atagatcatt ttcttggatc aacatggcca
    12481 ttttaaaatc tttaaatcca ttataaccaa gtttttttgt aaattgaaaa aaagtagagt
    12541 cagcaatgcc cagttcactt gctaaattgc taataggact atgacttact ttgcttggat
    12601 tttctaaaat ataatcggcg atagcctgtt cttttgggct gaagtcgttg tacattgttt
    12661 tgatttgtag tcttatggag acgctcatga gaattcctca ttttcataat aagattatca
    12721 ttttttccgt tctcattaat gttaaagata caaggagagt aggaaaaaat caaacaaaaa
    12781 atatttttgt aaaatctatt tacaaaaaaa tttttttgta taatgagggt ataagaaatg
    12841 gaggcgctat catggaaatt ggtgtaattg gtttgggaaa aatgggattg aatttagctt
    12901 taaacttaaa agagcaccat cacaaagtac aaggactcga catttcaagt acagctgtta
    12961 gtcaggcaag agaaaatgac attcctgctt atcaagagat ctctgaattt ctagctactt
    13021 ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg agagataacc gaaaacatgt
    13081 taagaaaact ttttccaaaa ctcggaccag gagacattat tattgaaggc ggaaactctt
    13141 attataaaga ttcaatccgt cgagcagaag agtttcagaa aaatgaaatc ggttacttgg
    13201 attgtgggac ttctggagga atcgaaggag cacgacatca agcctgctta atgattggag
    13261 gagataaaga aacttttcta tccgtggaac aattattcaa agatgtagca attgaaagag
    13321 gatatctgta tgctggtgca tccggaagcg gacacttctt gaaaatgatc cataatggaa
    13381 tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca acttgtacaa aaaagtgagt
    13441 atgcttttga cttggaacaa gtcgcacgtg tttggaatca tggttcggtg attcgcggct
    13501 ggctgatgga aatcatggaa gatcagttaa acgaacatcc caatttaagt aattatcggg
    13561 gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga aacagcgcta gaaatggctg
    13621 ttccagttcc agtaattgca actagtttgt tcatgaggaa tctttcacag gaagaagata
    13681 gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt tggcggacat gaaatagttg
    13741 aaaagggtga gtaaaatgcc agattatcat atagcaatcg ttaattccag cagtttcgga
    13801 agagtctttc cacaccactt ggaaagatta aagtcagttg gagacgttca tttctttact
    13861 gttgatcaag agattccagg aaaagaacta gcggagttac ttaaaggatt caatatcatt
    13921 attgcaagtg ttacgccatt ttttcgacga gatttttttg aaaacaaaga tgaactgcta
    13981 ttgatttccc gacatggtat tggttacaac aatattgatt taaaagcagc aaaagaacac
    14041 cagacaatcg tatctatcat acctgcttta gttgaacgaa atgctgtagc agaaaataat
    14101 ataactaatt tgttgtccat gcttcgacgc acgacacaag cacaagcaag agtcaaggac
    14161 gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc tgtttaacaa aacagttggt
    14221 gtgattggtg caggaaatac cggaagcgga gtaatcgaaa ttttgcgtaa cggttttcgc
    14281 tgtgatgttc tagcttatga tccttacaaa tcagatttat acatcgaaag ctttggtgca
    14341 aaaaaagtag aacttcaaga attactggaa caatcagata tcatttgttt atgtgcgaat
    14401 ttgacagaag agaactatca catgatttct gataaagaag tcgatcagat gaaagaaaat
    14461 gtttatctat ctaatagtgc aagaggcgct ctagttgatg aagaagcgat gattaatggt
    14521 ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt tagaagaaga accgggacgt
    14581 caagatcatc cgtatttagc gtttgaacaa gtagtgatta cgccacatat atcggcctac
    14641 acaagggaat gtttagaagc aatgggtgaa aaatgtgtca gagatgtcga acagatcagt
    14701 cagcaccttc ttcctgaacg ttctgtccag acaaagagca actatataaa aggatgatga
    14761 agaaaatggt gaacggttta aaagtgaaaa caggccctca attttattta tatgaagaag
    14821 gtggtatttc aaaagtttct gatctcttga aatcatacgg cgcgaaaaga gtactggtca
    14881 cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt agtatttttg aatgacgaaa
    14941 cgattcaatt tttttatcat cgttattctg gagaatgtag ttatgctgaa gccagacgaa
    15001 tagctacaat catcaaaaaa atgaaatcga tttcgtagtt ggcgttggcg gaggaaaact
    15061 gaccgatcta gtgggttata gtgccaatct tgcaagaatc gatttcggag tcatccctac
    15121 tttagctagt aattgtgctc catggacacc tcttgctgtc atgtataagg agaatggaca
    15181 agcagaaggg aaaacagaac acttttacag acaagctgct ttttttataa cagatcccca
    15241 attagtgatt gattcccctg ttccatattt cattgccggg ttagcagata cactagcaaa
    15301 atggtatgaa tctgagctca tcttagaaca agattttttg caagatgaat catttttgaa
    15361 gctagcacaa gatactgcga agatctgcaa agaagagatt ttgaatcatt ctgctaaagc
    15421 aatccaagat atggcacaaa gaaaactgac atcggagttc aaacagcttt cagagattat
    15481 ctttgctgtt gctggtttag ttggaggatt aggagataaa tacgcaagaa atgcggcagc
    15541 acatgctatg catgacgcta tcagtaaata tattccggaa agccatcgtt ttctacatgg
    15601 agaaaaagta gcgtatggga ttttctatca actggcacta gaaggtcgct gggaaaaaat
    15661 agacgagtta tatcctttgt atcgggaatt agaactgccg gtttctctag aacaaatggg
    15721 attatttccg aaagataaac agataataga taaaatggct gaatttattg attcgaaaga
    15781 gaaagtgcat ttgattccta tagaggtaac acagaaatca ctgatacagt caatgatgga
    15841 actggaaggt tatatcagaa agatctgaag gaggaggaca catggaaaca ttaagtgtag
    15901 tacaaagttt gttgattgct ttatgggtag ccgcggttat gtcccgctgg ttaggtggag
    15961 gagccacgtt gaccttacgt ttttctcctt tgatgactgg attagtcgtc gggttgatca
    16021 tgggggaagt tgcacaagcg atgattgtta cagccgcttt gcaaatgatt tatatggggg
    16081 ttttttctcc aggaggatca atgccagctg aaccatctat tgcagcagct atcgcagtac
    16141 cagtcgcatt attaggggat ctgtcgccag aagcagcgat tgccgttgcg gtgccagtcg
    16201 gattgctcgg aagttacttg tatcagtttc gttttttcat caatactttt ttaggtaaat
    16261 atacagacaa agctgtagaa gatttgaata caaaagctat ggcccgatca attattcttt
    16321 atccaacggt tgcctcattt ttattattcg ttccgcttgt tttcattgct ttatatttag
    16381 gggcgccatt gatcgctgat gtaatcaaag ctttagaggg aacagtcgtt atccacattc
    16441 ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc gacaactgta tacgttatcg
    16501 gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt tatgagtgtt gttttgaaat
    16561 ctttagatat tacgatggtt acttatgcca tttttgggat tattatcgct ttgatctttg
    16621 tccagtcgca aaaagggaaa caagtacagc ctgccacaag caataacaat tcagcatctt
    16681 ttgatgacga agatgactat gatgacggat tttaatttag gaggaatggg aaatggctga
    16741 aataatggat aatcaaacag gtgctcctga agaaatcacg aaaaaagatg taacaaaagc
    16801 ctatctgaga tggcattttg caaacgaaat tcctcactct tttgaacgtt acttggcgcc
    16861 atcactacta tacggaatga tgccaatctt gaaaaaactt tataaagatg aagactcttt
    16921 aaaagcagca tataaacggc agttactgtt cttcaacact caattaagct ggggtggcgg
    16981 tgtgattact ggcctaatgt cttctatgga acagcaaaga gcagaagaag agtatgaaga
    17041 aaaagagatc ttgatgcagg atgacttgat gtataacacg aaagcgggat tgatgggggc
    17101 actagcagga atcggagatg caatcgattc aggaaccgtc caatatattt ttatcgcaat
    17161 cgcggtacct tgggcacaac agggaagtcc tttaggcgca ctttttcctt ttatctgctt
    17221 tgggttgtat caggttttac taggggtatt tttcgcaaga caagctttca ctatgggccg
    17281 taatgctaca ggcctaatgc aaaacactgg tgttcagaca gcgattgaaa tgctatcagt
    17341 tttagggttg tttatgatgg gggtgcttgc gggaaactat gtaaaagtag aatcttcatt
    17401 gaaatttgcg atatccggac gtgagtttgt tatccaggaa attcttgatc aaatcgtgcc
    17461 agggatatta cctttagctg tcgtaatggg tgtgtacttg ttctatacga aaaaaggatt
    17521 gaaagtcaca caagcattat tatggctgac tggaatatta attgtgctag caggaatcgg
    17581 tattttataa aaagaaggga acgtgaataa gatgggtgta gtcaatttag cgcgtgtgga
    17641 tgagcgtttg atccatgggc aagtaatggt aacgttatct caaaaaagtg gagtgaattc
    17701 catttttgtt gtagacgaag ttgtagcaaa agataaattt atgagagatc tttacaaaaa
    17761 tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca ccagagaaag ctaaattcta
    17821 ttgggatgaa tatcaattta aagaatacaa ttgtattttg atcgcaaaaa cagtccaaac
    17881 gatttacgac ttagtaaaac acggaatccc catggaagaa ttgaatattg gagggattgc
    17941 tcaaaaaaat cctgatacag atcttttagt gacgaaatct gtttatttaa ataaatcaga
    18001 tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta aagaatattt attttcaagc
    18061 cactccatct gcacctaaaa caggattaaa agatgtattg aacaagtttg atttgtcata
    18121 aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg aagaagaacg agctgtttcg
    18181 tgattgggaa tttcgttatc gctatattta ccgtaagcgc cgtacaaaaa agagtaaaca
    18241 gcgttttctt tcagcattag tatcagatat ttacagtatg agaacagatg tgacagtcat
    18301 tgcttacgat acgctagcct accgatcaaa aaatatttat gttggagata tcgaaaaagc
    18361 agagaaagtt atctgtactt attacgatac acccgttcat gcattaggaa gttatttcat
    18421 gtttgattgg aaagaccaaa ggaaaaaaac aatctactct atattattgt ccttcatttt
    18481 gttgttcagt ttaggttggt ggggaatgat gatatataac aaaaatcctc atcacgtatt
    18541 cgatctgcta tccgtataaa caggtatcac tgtactagca tttgggagct actttttctt
    18601 attgggaaaa gcagctcgcg gatggcctag cagacaaact tttattcgaa atacttcatc
    18661 catattaacg atgctagaaa tgatccgtac gattgatgat ccgagtgtag cgtatgcgtt
    18721 tgttgatgaa ggctgttatg gagaaaaggg cttagacagc gtgagatcgg gtatgaaaaa
    18781 agaggctatt cttttttatc tagactctgt tggggcagat acaccgctac agttttcggg
    18841 aaattatttt tcaaataaag aacagtggct gaaacaagtt gataagttga aagaaaaaaa
    18901 cgtcaattat atttttagtg caagaaaaaa gcaagcgcag ttcttctatt tgaccaaaac
    18961 agatttacga gggaaaacat ttaattggca aaatgccaat cagattattg ctctttttcg
    19021 ataagtaaaa agtgcaaaac aaggagtgag aagactaatg ttggaaatca tgatcgttac
    19081 acatggtaag ttgagcgaag gactgaaaga tgcggcggaa gtaattgtcg ggacatcgag
    19141 ccatattgaa acaatgtgct tagagtctgg ggaggacatc caaacattcg gagagaaggt
    19201 caaagaaaaa ttaactatga tcaacacagc agaacccatg ctagtatttg ttgatctaat
    19261 tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat gaactgactg aagaaaagaa
    19321 agcagccact tatgtcatag ggggcgtgaa tctgccaatg ttgttagaag caatcaatca
    19381 tcagatgctt cacacaccga tagaagaagc ggtggaacaa attgtcaaac aaggaaaaga
    19441 taatttaact gtttggcatg cttcagcgga agaaaaaaaa ttagatgagg acgattttta
    19501 gaaggaaggc tgaaaagatg aagtggggat ttagatggta tggtgaaaaa ggggattcga
    19561 tcccattaaa atatgttcgc caaataccgg gaataaatgg gataattgga actttgctga
    19621 ctaaaatgcc tggagatgtt tgggagattt cagaaattga ggagttgaaa gcatctgttg
    19681 agagccaagg actggaactg cttggaattg aaagtgtagc gatccacgat gcaatcaagg
    19741 cagggacaga tgaacgagat tactatattg ataactatat acgaacaatc aaaaacttgt
    19801 ctcgatgtgg ggttcgattg atttgttata gcttcaaacc aatttttgga tgggcgaaaa
    19861 ctgatttgtt taatgaaaac aacgatggaa gctattctct tttatacgat cagaaaatcg
    19921 tcgatcagat ggagccagga gaaatgtatc aattgataca cagccagtca aagggattca
    19981 aattgccggg ttgggaagaa gaacggttga aaaaattcgc tcagctggaa aaactgtatg
    20041 aaggaatgac cgaagaagaa ttatttgaaa atctgactta ttttttagaa aaagtgattc
    20101 cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc agatgatccg ccatgggaac
    20161 tttttggttt tcctagagtg acgaaaaatc ttggcgactt gaagaaaatt ctaaatgcag
    20221 tagattctcc atataatgga ctaacgctgt gcacaggatc tttaggggca aatccggaaa
    20281 acgatttagt tgaaatcatc catgaggtag gttcgcgcat ccattttgtc cacttcagaa
    20341 acgtggagtt tttaggagaa agaaagttca aagaaacggc acatccctct acagaaggct
    20401 cccttgatat gtatcatatt atgaaagcgt tggtgcaaga agggttcgac ggtcctatac
    20461 gccctgatca tggtagaacc gtgtggggtg aagtggctat gcctggatat ggcctgtatg
    20521 atcgtgcaat gggactcact tacatgcaag gtctatatga ggcgataagt aaggaaaaac
    20581 cactgggaga gcattatgaa taaaatcaag ctcttcatct ttgatatgga tggcctttta
    20641 ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat cagcacaaaa gtatgattat
    20701 gaaatgcgta aggaagtcta ttatttacta actggccaaa cagaaatggc gataagagaa
    20761 caaatgggca ttttgtacgg agaagatgtt ccatatatca aatggcgaga agcaatcaat
    20821 caatataaag aaaaaatcgt gaaagaagat aagagagtat atacgaaaaa aggagcagaa
    20881 gaaattttat cttttgcaaa agaaagagga atccatacaa tcgtggcttc gtctaataca
    20941 cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat atgccttgtt tgatcaaatc
    21001 atttcagggg atgatgtaaa aaaaggaaag ccggaaccag agatcttttt gaaagcttgt
    21061 tcaaaaatga atattcctcc aagtgaagca cttgtatttg aagactcgat tgcagggatc
    21121 gaagcagcaa ggcgagcggg cattttgtct tttctcatca aagatcattt gatagggttg
    21181 cccgatcata atgggaagca taagttgaaa gtagatgtaa gtttatatga atccaataaa
    21241 gcagactatg aattttatga cctgcatcaa gcaaaacgat ttttagaaag taaagggttg
    21301 tatctctaat aaagaggact attttctagt cctctttatt tattgtcctg cacgactgag
    21361 ggaacagatg aaaaagaagt aattttttat tttgaagtat ctaccttatt tgtagtgaac
    21421 aatttagaac aaacacaaaa cgcatctact gttatctacc agtagatgcg tttaaagaga
    21481 agaacgagaa tcgtccatat gagggtttcc actccttatg cagatttttt taattcttgc
    21541 actgcttgtt cgatcgtaac acctgtcgct acatgattgg tattttcttt gtcaaaaacg
    21601 acaaatagat tcaaatctgt atccaaggtt actcgatatt gtatatcttt gttatagaat
    21661 gtcatagcca ttctcctttc tttaaatact tgctgaaagg caacgaacgc gttgataacg
    21721 aaattccatt tataagtata ccaccaattg aaaggttttc atagttaaga aattttaaag
    21781 tcaaaagttg cagataaaag caaataaaca agaaaacaaa aagtgaatca atcgcggtta
    21841 ttcaactttt tcttcgattc gaagacaata gaagacaatg aattttatat ttcattgcat
    21901 tatccttgtg ttattagaaa aagcatgata tattaaatga gtaatctatt ttgaaacgta
    21961 atttgagcga tatatctaca tagataaaac tccttttgcc tatcaaatat ttattgcaac
    22021 gaaaaaacgt acattgatac gtatcaggag gaatttattt atgaataacg gtacagtaaa
    22081 atggttcaac gcagacaaag gttttggctt tatcactggt gaagatggaa atgatgtatt
    22141 tgcacatttt tcagctatcc aaggtgacgg cttcaaaact ttagaagaag gccaagcagt
    22201 gtcttacgat gttgaagatg gtcaacgtgg ccctcaagca acaaacattg ttaaagctta
    22261 ataaaaattg acttttaacc gtcttttcga aagaaaagac ggtttttttg tacgaaaaaa
    22321 t
//
LOCUS       DBGZHO010000044        22269 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.044, whole genome shotgun sequence.
ACCESSION   DBGZHO010000044 DBGZHO010000000
VERSION     DBGZHO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.044"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            163..2697
                     /gene="secA"
                     /locus_tag="ACN3HL_001893"
     CDS             163..2697
                     /gene="secA"
                     /locus_tag="ACN3HL_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HHC8006750.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            2824..3925
                     /gene="prfB"
                     /locus_tag="ACN3HL_001894"
     CDS             join(2824..2895,2897..3925)
                     /gene="prfB"
                     /locus_tag="ACN3HL_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HHC8006751.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4030..4716
                     /gene="ftsE"
                     /locus_tag="ACN3HL_001895"
     CDS             4030..4716
                     /gene="ftsE"
                     /locus_tag="ACN3HL_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HHC8006752.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4709..5593
                     /gene="ftsX"
                     /locus_tag="ACN3HL_001896"
     CDS             4709..5593
                     /gene="ftsX"
                     /locus_tag="ACN3HL_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HHC8006753.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            5745..7193
                     /gene="cls"
                     /locus_tag="ACN3HL_001897"
     CDS             5745..7193
                     /gene="cls"
                     /locus_tag="ACN3HL_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HHC8006754.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            7530..8387
                     /locus_tag="ACN3HL_001898"
     CDS             7530..8387
                     /locus_tag="ACN3HL_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HHC8006755.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8502..9422
                     /gene="pstC"
                     /locus_tag="ACN3HL_001899"
     CDS             8502..9422
                     /gene="pstC"
                     /locus_tag="ACN3HL_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HHC8006756.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9422..10306
                     /gene="pstA"
                     /locus_tag="ACN3HL_001900"
     CDS             9422..10306
                     /gene="pstA"
                     /locus_tag="ACN3HL_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HHC8006757.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10321..11127
                     /gene="pstB"
                     /locus_tag="ACN3HL_001901"
     CDS             10321..11127
                     /gene="pstB"
                     /locus_tag="ACN3HL_001901"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHC8006758.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11143..11901
                     /gene="pstB"
                     /locus_tag="ACN3HL_001902"
     CDS             11143..11901
                     /gene="pstB"
                     /locus_tag="ACN3HL_001902"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HHC8006759.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11914..12591
                     /gene="phoU"
                     /locus_tag="ACN3HL_001903"
     CDS             11914..12591
                     /gene="phoU"
                     /locus_tag="ACN3HL_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HHC8006760.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            13155..13847
                     /locus_tag="ACN3HL_001904"
     CDS             13155..13847
                     /locus_tag="ACN3HL_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HHC8006761.1"
                     /translation="MLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAIL
                     FVVIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVI
                     GSMANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIA
                     VLFFLAVRRLKK"
     gene            13844..14611
                     /locus_tag="ACN3HL_001905"
     CDS             13844..14611
                     /locus_tag="ACN3HL_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HHC8006762.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            14711..16279
                     /gene="liaX"
                     /locus_tag="ACN3HL_001906"
     CDS             14711..16279
                     /gene="liaX"
                     /locus_tag="ACN3HL_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HHC8006763.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENSEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16455..16763
                     /locus_tag="ACN3HL_001907"
     CDS             16455..16763
                     /locus_tag="ACN3HL_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HHC8006764.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            16763..17113
                     /locus_tag="ACN3HL_001908"
     CDS             16763..17113
                     /locus_tag="ACN3HL_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HHC8006765.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            17279..18217
                     /gene="hprK"
                     /locus_tag="ACN3HL_001909"
     CDS             17279..18217
                     /gene="hprK"
                     /locus_tag="ACN3HL_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HHC8006766.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18232..19062
                     /gene="lgt"
                     /locus_tag="ACN3HL_001910"
     CDS             18232..19062
                     /gene="lgt"
                     /locus_tag="ACN3HL_001910"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HHC8006767.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            19106..20131
                     /locus_tag="ACN3HL_001911"
     CDS             19106..20131
                     /locus_tag="ACN3HL_001911"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HHC8006768.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20146..21084
                     /gene="galU"
                     /locus_tag="ACN3HL_001912"
     CDS             20146..21084
                     /gene="galU"
                     /locus_tag="ACN3HL_001912"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HHC8006769.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21209..21658
                     /locus_tag="ACN3HL_001913"
     CDS             21209..21658
                     /locus_tag="ACN3HL_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HHC8006770.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            21651..22253
                     /locus_tag="ACN3HL_001914"
     CDS             21651..22253
                     /locus_tag="ACN3HL_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HHC8006771.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
BASE COUNT         7368 a         3873 c         4907 g         6121 t
ORIGIN      
        1 tttttgagtt tcctcctctt ttagatgaaa tatgaataaa ttatgaagtt cttactttaa
       61 tacgcttaag atatttcaat tatctataac taatgataaa atgaaaagta aagtctacat
      121 agtctggata atacacagaa ggaaaaggag attacacaac gcatggccaa tttgattcgt
      181 tcacttatcg aaaacgataa gaaagaacta aaacgtttag atagcattgc aaaaaaagtt
      241 gaagcatacg ctgaccaaat ggcagcatta actgatgaac aattacaggc aaaaactgct
      301 gaattcaagg gcagatacca aaaaggagaa acattagatc aattacttcc ggaagctttt
      361 gcagtcgtcc gagaagcagc aaaacgtgta ttggggttat atccatacca cgtacaatta
      421 atgggtggga tcgtgcttca cgatgggaat atccctgaaa tgcgtactgg tgaaggtaaa
      481 accttgactg caacgatgcc ggtgtatctg aatgcgttga ctggcgaagg ggtccacgta
      541 gttaccgtca atgaatattt agcaacccgt gactcgacgg aaatgggcga gctttataat
      601 ttcttaggat tgacagttgg gttgaatatc aactcaaaat cttcggatga aaaacgcgag
      661 gcttataatt gcgatatcac ttatagcacg aataatgaat taggatttga ctatttgaga
      721 gacaacatgg tcgtttaccg tcatcaaatg gtacaacgtc cgctgaatta tgccattgtc
      781 gatgaagttg actcgatctt gattgatgaa gcgagaacgc cgctgatcat ttcagggcaa
      841 gcagaaaaat caacagcttt atatacaaga gcagacaact tcgtgaaacg tttgaaagaa
      901 gaagaagatt ataaaatcga tatacaatca aaaacaatca gtttaactga agcagggatc
      961 gaaaaagctg aagaaacatt cggtttggac aacttatatg acattgaaaa tactgcattg
     1021 acccatcact tggatcaagc attgagagcc aactacatca tgcttttaga catcgattat
     1081 gttgttcaag atggaaaagt attgattgtt gaccaattta cgggtcggat catggatgga
     1141 cgccgttatt cagatggtct tcatcaagcg atcgaagcta aagaaggcgt agagatcgaa
     1201 gacgaaacga aaacgatggc gacgatcact ttccagaact atttccgtat gtacaagaaa
     1261 cttgcgggga tgactggtac agctaagaca gaagaagaag agttcagaga gatttataat
     1321 attcaagtat accagattcc gacaaaccgt ccggtcatcc gtgacgatcg accagatttg
     1381 ctttacccaa cattacaaag caagttccat gctgtcgtac aagatatcaa agatcgctac
     1441 cgcaaaggac agcctgtctt agtcggaact gttgcagttg aaacatctga gttattatca
     1501 gatatgctga atcaagaacg tattcctcat gaagtactga atgcgaaaaa tcactttaaa
     1561 gaagcagaaa tcatcatgaa tgcgggtcaa aaaggtgcag tgacgattgc taccaacatg
     1621 gctggtcggg gaacagatat caagctaggg cttggcgtaa gagaacttgg tggcctagca
     1681 gttatcggga cagaacgaca tgaatctcgt cgtatcgata accagcttcg aggacgtgca
     1741 ggacgtcaag gagaccctgg tatgtcacaa ttctacttgt ctttagaaga tgatttgatg
     1801 aaacgattcg gttcagaacg aatcaaagct ttcttagatc gaatgaagat cggtgacgaa
     1861 gatgctgtga tccaaagcaa gatgctgacg aaacaagtag aagctgcaca aaaacgcgta
     1921 gaaggaaaca actacgacac acgtaagaac gtcttgcaat acgatgacgt gatgcgtgag
     1981 caacgtgaag taatctataa acagcgtcaa gaagtgatca tggaagaaaa aagcttatct
     2041 aaaccactga tgaatatggt caaacggaca atcagtcgtg tggtagatgc gcatacgcaa
     2101 ttagaaaaag aaaattggaa tttggaaagt atcgtcgatt ttgctggcag cacgcttgtc
     2161 catgaagaca gtatttccct tacagatatc gaaggaaaaa cctctcaaga aatcaaagaa
     2221 tatctaaacg aacgagcaca agaagtattc aataccaaag cagctcaatt gaacggacca
     2281 gagcaactgc ttgaatttga aaaagtcgtg atcttacgtg tcgtggactc taaatggaca
     2341 gatcatattg atgcaatgga ccaattacgt cagtcaatcg gcttgcgtgc ctatggtcaa
     2401 aacaatccat tagtcgaata ccaaacagaa ggttataaga tgttcgaaga tatggtaggt
     2461 gccattgaat atgaagtcac tcgtatcttc atgaaagctg agatccgtca aaacgtacaa
     2521 cgtgagcaag tttctcaagg aacagcttct cactcagaag atggagatgc caaagaaaac
     2581 agtaatacta gcgcgaaaaa acaaccaatc catgtgaaca aggttggtag aaatgatcct
     2641 tgtccttgtg gaagcgggaa aaaatataag aactgtcacg gaaaagatgc aaactaattt
     2701 ctgacagcag gattggtgag acaaattctt ttttaaagaa tttgtctcac cttctttctg
     2761 ttatttgacg attctgttag actagatata ataaaaaaag tatagtgaaa gaaggaaaaa
     2821 aacatggaaa tatccgaaat tcgaaatctc ctgacagaaa tgcaggaaaa ggtcacaagc
     2881 ttcaggaggt ctctttgact tagaccagct ggaagaagac attgcggaag cagaagcaaa
     2941 aatggctgaa cctggttttt gggatgatag cgaagctgct caaaaagtga tcagtgaaaa
     3001 caatgcaaat aaagaaactt atgatcaatt ccattctctt gctgaagaac tggaagaaat
     3061 cgaattgatg gtggagatgt tgcaggaaga acctgatgca gtaatgcaag aagaagcaga
     3121 agcacgtatc aatgcgctag atgaaaaaat gaatacgtat gaattatcta tgttgttaga
     3181 tggtccttat gatcgaaaca acgccatcgt cgaattgcat ccaggggctg gcggaacgga
     3241 gtcccaagac tggggcagca tgcttttacg catgtataca cgctgggcag agcagcatgg
     3301 gtatcaagta gagacactag attatcaagc aggcgatgaa gcaggaatca agagtgtgac
     3361 cctactgatc aaaggacaca acgcatttgg ctatctgaaa tcagaaaaag gtgttcatcg
     3421 ccttgtacgt atctcgcctt ttgactcagc aaaacgtcgt catacttctt tttgttcggt
     3481 agatgtgatg ccagagcttg atgaaacgat cgatatagaa atcaatccag atgatttgaa
     3541 gatcgacaca tatcgggcga gtggtgcagg tggtcagcac atcaataaga cagaatccgc
     3601 tgtacgaatc actcacttgc ctacaggaac agtagtagcg agtcaggcac aacgttcaca
     3661 attgaaaaac cgggaacaag cgatggggat gctgaaagct aagctttacc aattagaagt
     3721 ggaaaagaaa gaacaagaag cagctgcact gagaggagaa caaaaagaaa tcggctgggg
     3781 atcacagatc cgttcttatg ttttccatcc atattctatg gtaaaagacc atcggacaaa
     3841 cgtagagaca ggaaatgtcc aagctgttat ggacggagat cttgatttat ttattgacgg
     3901 ctatttgaaa atgcatctgc aataagagcc ctttgttaaa ttgaaataaa attgtaagat
     3961 tttgcaagca agttgaaaca ttgccatgct ataatagcta aagactgaaa aagatatgga
     4021 gagaacgcca tgattgaaat gaaggatgta atgaagaagt actcaaacgg taccactgct
     4081 atccgcaatc tctcgattgt catcgaacaa ggagagtttg tgtatgttgt tggtccgtct
     4141 ggagctggta aatctacatt catcaaattg atgtatcgag aagaaaaagc ttcaaaagga
     4201 actttgaacg tcgcaggtca tgatctaata gccatcaaaa accgcgaagt tccttatcta
     4261 cgcagagaaa tcggcgtggt gttccaagac tataaattat taccaagaaa aacagtatat
     4321 gaaaatgttg cgtacgccat gcaagttatc ggcagaaaac ctcgggatat caaaaaacga
     4381 gtaatggaag tgctggatct tgttggtttg aaacacaaag tccgagtctt tcctagcgaa
     4441 ttatctggtg gggaacaaca acgtgtttct attgcccgag caatcgtaaa tacacctaaa
     4501 gtacttatcg cggatgaacc gacagggaat ctagatccgg aaaactcatg ggaaatcatg
     4561 aaactattag atcggatcaa tgcacaagga acaactgtcg tgatggctac acataacagt
     4621 acgatcgtaa atacgattcg acaccgagta attgctatcg aaaacggccg cattattcga
     4681 gaccaagcgg aaggggaata tggatacgat gattagaacc tttttccgcc atttattaga
     4741 aagtatcaag agtttgaaac gtaacggctg gatgacagta gcttcggtca gtgcggtaac
     4801 gatcacgttg actttagttg gtgtgttcat ggcggtcatc atgaacgcaa ccaaactagc
     4861 acaagatata gaaggaaacg tggatgtatc tgtgttcgta gacattggta caaaagacga
     4921 agagatgaaa aaattagaaa aagaattaaa tgacttagat catgtcaaaa aagtcgaatt
     4981 ttcaagcaaa gaacaggaat tgaagaaaat ccaaaacgaa atgggcgatt cttggaaatt
     5041 gtttgaaggg gataataacc cgttatatga tgtatacgta gtaagtgcta ccgatccttc
     5101 ttatacaaaa caagtagcag aaaaagcggc agatttgaag aatgtttccc gttctgatta
     5161 cggtggggct tcctcagatc ggattttcca aattgctggt gcagttcgaa catggggatt
     5221 agttgcggcg gcattgctgc tgtttgtagc aatgtttctc atttctaaca cgattcggat
     5281 cacgatttta tctagacagc gtgaaattca aatcatgcgt ttagtagggg caaaaaatgg
     5341 atatatccgc tggccatttt tccttgaagg tggttggatc ggcttaatcg gtgccattct
     5401 tccgatactg atcattacat ttggttacgc atggttttac caattgatca atccgtcatt
     5461 attacgatct cattattcat tgatccatcc agaaaatatc gtttggaaaa tcaatctttt
     5521 gatggtcggt attggtgtga tcattggttc actcggctcg atcatctcta tgagacgttt
     5581 cttgaaattc tagtgtcaca agataaatat aatcagaaag ttggacgatt tcgttccagc
     5641 tttctttttt tatcagctag gtggagtaaa tggggcggct tttttctctt tactttaaaa
     5701 aacaacttgg gtattcttaa gttggtagaa aaagaggtga agccgtgaag attatcgttg
     5761 acaatttttt tacgatcctt ttgattatga atattttgct ttcctttatt atcgtttttc
     5821 gagaaagaaa ggaaactgcg caaacatggg catggctgct cgttttgatg ttcattccag
     5881 ttgtaggatt tattttatat atttttttag gaagagggat ttccaaagag aaaatctttg
     5941 atttgaagat ccaagggaaa atcggtaaga atctagaaat cgaagaagat aaacaagcat
     6001 tgatgcgagg gctttatcct catccgccta ctggacaagt agatgtgaaa caattgatct
     6061 atatgcttac tgtatttgaa agtacgcttt atacgactaa aaatgaaatc actttattta
     6121 cagatggtcg tgaaaaattc gatgcgctga tcgaggatat caaacaggca gaagaccata
     6181 tccatttcca atattatatt taccgcagtg atacattagg tgaagaagtt cgagaggcat
     6241 tgacagaggc agcaagacgc ggagtaaaag tcagagtcct tcttgatgca tggggttcca
     6301 cacaagtttc ttctagtttt tttcagaatt tgaaaaaagc aggtggagaa gtcgcatttt
     6361 tctttcctct attcgttccg tatatcaatc ctcgaatcaa ttatcgcaat catcgtaaaa
     6421 tcgtagtgat tgatgggaaa atcggatata caggtgggtt caatgttgga aacgaatatc
     6481 taggattggt aaagaaattt ggttattggc gagacaatca tctgcgtatc tatggagaag
     6541 cggtttacac cttgcaaaac cgttttttga tggactggaa ttctcagcat acaaaagaag
     6601 taggatattc accggaattt ttcccgacca ttcattctac aggtgatatg gctgttcaaa
     6661 tcgtgacaag cggaccagat accgaacatg agcaaatcaa aatgacatat ttgaaaatga
     6721 tttcgttagc caaacgggag atattgatcc aaacgccgta ttacataccg gatggatcga
     6781 ttcatgaggc attgaagttg gctcttctct caggcgtaaa agtccatatc caaataccta
     6841 acaaaccaga tcatcttctc gtttactggg caacgtattc tttcgctgca gagctgatcg
     6901 agtatggggc aagaatcgaa acatatgaaa atggatttat ccatgcaaag acgatgatta
     6961 tcgatggcgg catcgtttcc gttggttcag ctaatatcga cgttcgctca tttagattgg
     7021 attttgaagt caatacactg atctatgatg aacgaatggc ttctcgcgta agaaaagcat
     7081 tctttgaaga ttcaaagatt tcgacgcatc tcacaaaaga agtgtatgaa aaccgaggga
     7141 tgatgatcaa gatgaaagaa ggattagcaa gactgatttc gccgctcctt taaaatacaa
     7201 aaaggacagg agagccatca atagatggaa atctcgcgtc cttttttctc ggggccattt
     7261 ctgagagtac gtcagaaatg gagaaagcgt ctcgcatgag cgaaattaac tttggggtat
     7321 ctcttgtttt ttggggaaag caagaaataa gctaatatat gctattaaaa gagacacatt
     7381 tcaaagccag tatagcatag aaacttttaa tgagatagct ttttttgcaa ttatgagaat
     7441 ttattttgtt atttaatgat tttgattcgt tttcatcaag taatgaaaat gatagaataa
     7501 acatacttta ggattaaagg agatttctaa tgaaaaaact aaaattattc ttaccaataa
     7561 taggattagc tattctttta tcaggctgtt caaagtggat tgatcgagga gaatccatta
     7621 ctgcagttgg ctcttctgcc ttacagcctt tagtagaaac ggttgctgaa acctaccagg
     7681 cagaaaatcc tggaaaattc atcaatgtac aagggggcgg aagcggaact gggttgtctc
     7741 aagtacagtc aggagcagtc gatatcggaa attctgattt gttcgcggaa gaaaaatcag
     7801 ggattgatgc ttcggcatta gtcgatcatc gagtagcagt tgttggaatc actcctattg
     7861 tgaacaagga tattggcgta aaagatatca gtatggaaaa cctgaaaaaa ttatttacgg
     7921 gcgagatcaa aaactggagt gaagtcggtg ggaaagatca gccagtagtt atattgaacc
     7981 gtgcatcagg aagcgggacc cgtagtacgt ttgaaaaatg ggtattggac ggagaaacag
     8041 ctgttcaggc acaagaacaa gattcaagcg gaatggtgcg ccaaatcgtt gcggacacac
     8101 ccggagcaat cagctatgtt gctttttctt acgtttccga tgatgtggat acgttgaacg
     8161 ttaacggtgt ggaaccaaca gatgaaaatg tgacaacgaa caaatggacg atttgggcat
     8221 atgagcatat gtacacaaga gaccatccaa aaaaactgac aaaagaattt ttagactata
     8281 tcttatctga tgaagtacaa gataatattg tcggagagct aggctatatc cctgtttcac
     8341 atatgaaagt tgaacgtgat tggcaaggaa acattgttaa agagtaatct ttacacaaaa
     8401 tttacaaact tagctaaact tttacatgtt attaaaacca aattgatgtt caatttgtac
     8461 actgagtgag tatgttaaac ctgattaagg gggagtcatc tgtggaagat gtgaaaaaag
     8521 tattattaac aaaatcaaaa cgttcaaaaa tggaacagcg cggaaaattc attagttttt
     8581 tgtgtatcgc gctgatcgtg ttggttgtat tatctatttt ttattttgtc gctagtaaag
     8641 gattggccac cttttttact gataagatca atgtatttga ttttctgttt ggtacagatt
     8701 ggaatccaag ccaaatagga gcaaatggga aacccatggt aggggcattg cctatgatca
     8761 caggttcatt tattgtgacc tttttatctg ctattgttgc cacaccattt gctattggag
     8821 cagcagtgtt catgacggag atttctccta aaaacggaac gaagatcttg caaccggtca
     8881 tcgagctact tgtaggtatt ccgtctgtcg tttacggatt tatcggttta tctgttatcg
     8941 tgccttttgt cagaagtatc tttggcggga cagggttcgg tatcttagct ggtacatttg
     9001 tgttattcgt tatgatctta ccgactgtca caacgatgac tgtggatgca ttaaaggcag
     9061 tgccgcgaca ctatcgggaa gcttcattag cgctaggtgc cacaagatgg caaacaatct
     9121 acaaagtggt gctgcgagca gcagtgcccg gaattttaac agcagtcgtt tttggtatgg
     9181 ctcgtgcgtt tggcgaagcc ttagctatcc aaatggttat tggtaatgcg gcattaatgc
     9241 caacaggact tactactcct gcttctacat tgacgtccat cttgacaatg ggaatcggaa
     9301 atacaatcat gggaacagtt gaaaataatg tgttatggtc attagcgctg atcttgctat
     9361 tgatgtcatt attctttaat atcgtgatcc gtatgattgg gaagaaagga gagctgaaat
     9421 aatgaacgca aaacgctcag ataaaattgc tacaggtgtt ctatatgtgg tttcagggat
     9481 catcgtattg atcttagcag ctttattact ttatatctta gttcgaggaa taccgcacat
     9541 ttcatggtca ttcttgactg aaccttccaa agcctaccaa gaaggcggtg ggatcgggat
     9601 tcaattattt aactcgattt atttgctttt gattaccatg atcatcagtt ttcctatctc
     9661 tttaggtgcg ggtatctacc tttcggaata tgccggaaaa aactggctga cagacgtgat
     9721 ccgtacgtct atcgaaatct tgagctcttt gccttctgtt gttgtcggtt tattcggttt
     9781 cttggttttc gttattcaat tccagtatgg tttctcaatc atttctggtg cattagcttt
     9841 gaccgtattc aacttgcctc ttttgactcg aacggtcgag gaatctttac aagcggtcca
     9901 ttacacacaa cgagaagctg gattggcgtt aggtttgtca cgctgggaaa cagtgataaa
     9961 agtggttgtt ccagaagcga caccaggaat tttgactggt gtgatcctaa gttcaggaag
    10021 aatttttggt gaagctgccg cattgattta tacagctggt caaagcgcgc cagcattaga
    10081 ttttacgaac tggaatccat taagtgtttc tagtccgatc agcattttcc gccaagctga
    10141 aacactggct gtccatattt ggaaaatcaa cacagaaggt acgatgcctg atggtgtttc
    10201 tgtttcggct ggcgcttctg ccgtgttgat cattgctgtt ttactgttca acttcggcgc
    10261 tcgtgcgatt ggcaaacgat tataccgaaa aatgacttca gcctaaggag aagaagtaaa
    10321 atgaaaaaat ataattggaa tgaaacaaat gtcattacca tgccaaaaga taaggaagtt
    10381 gcattatata cgaatgatct gcatgtttgg tatggcgaca atgaagcaat caagggagtg
    10441 gatctagaat tcgaaaaaaa taagatcact gcattgattg gtccctctgg ctgcggaaaa
    10501 tccacgtatc ttcgttcttt gaatcgtatg aatgatggga ttgctaatac gaaaattact
    10561 ggaaagatta tgtataaaga cgtggatatc aatgcgcctc aagtggatgt ttatgaaatg
    10621 cgtaaacgga tcggcatggt gttccaacgc cccaaccctt ttagcaaatc gatttatgac
    10681 aatataactt ttgctttgaa acagcatggt gaaaaaaaca aaaagaaatt agatgaaatc
    10741 gttgaaacaa gcttgaaaca agcagctttg tgggatcaag taaaagatag cttggataaa
    10801 agtgccttgg ctttatctgg cggacaacag caacgtttgt gtatcgctcg tgcaatcgcg
    10861 atgaaacccg atatcttgct gttagacgag ccggcaagtg ccttggatcc tatttcgaca
    10921 ggaacggttg aagaaacact tgtaaacttg aaagaagact acacgatcat tatcgtgacg
    10981 cataatatgc aacaagcagc tcgtatcagc gactatactg cctttttcta tctaggaaaa
    11041 gtaatggaat atgacaaaac aaacaagata tttaccagac caaaaattca ggcaaccgaa
    11101 gattatgtgt ccggtcattt tggttaagac ggaggcctca acatgacaaa agaaattatc
    11161 tcatccaaag atcttcatct gtattatgga aagaaagaag cactaaaggg aattgatcta
    11221 agtttcaatc aaggtgaaat cacagcgatg atcggtcctt ctggttgcgg gaaatctacc
    11281 tatctacgtt cgttgaatcg aatgaacgat ctgattccaa atgtaacgat caccggaagt
    11341 gttttatata aagacaaaga catctatggt ccgaaaacag atgttgttga actaagaaaa
    11401 gaaatcggca tggtgttcca acagccaaat ccatttcctt tttctattta tgaaaatgtc
    11461 atctatggat tgaagttaaa aggtgaaaaa gataaaaaag tccttgatca agtagtggaa
    11521 gaaagtctga aggcagcgtc cgtttgggag gatgtgaaag ataaactgca taaaagtgcc
    11581 ttgtctttat ccggtgggca gcagcagcgt gtatgtatcg cacgtgtttt ggcagtgaat
    11641 cccgaaatca tcttattgga cgaaccaaca agtgcacttg accctgtttc tactgggaaa
    11701 atcgaaagta tgctgttaga attaagagag cggtatacga tgatcatcgt gacccataat
    11761 atgtctcaag cttcacgtat ttcagataag acggcattct ttttagatgg tcacttgatc
    11821 gaatacaacg atacgaagaa gatattcatg aatccagaaa aacaagagac agaagattat
    11881 atttcaggtc gatttggata aggaggaaac ggaatgctac gtacacaatt tgaagaagaa
    11941 ttgctgaatc tccataatca gttctacgaa atggggatga tggtgagcag cgctgtgcac
    12001 aagtcagttc gtgcatacat caaacacgat aaaatcttag ctcaagaagt tatcgaaaac
    12061 gatataaata tcaataatat ggaaacgcgt ttggagaaga aaagttttga aatgattgca
    12121 ttacaacagc cagttacaac tgacttgcgt atgattatca cggtcatgaa agctagctct
    12181 gatttagaac gtatggccga tcatgcggtg tccgttgcta aatccacaat ccgcgtaaaa
    12241 ggacagacga gaataccgga aatcgaaaaa gagatctccg atatgtccga ttacgtgaaa
    12301 aaaatggtgg acaacgtcct agttgcgtat gtcaaaacag acgaaaaaga tgcgcgtaca
    12361 atcgccaata tggatcaaag agtcaatgac tatttcaatc gaatctataa tgcaaccatc
    12421 aaaaacatgc aagaaaatcc tgaaacagtc atcagtggca cagactattt gaatgttgcc
    12481 agctatctag aacgaatcgg agactatgtg acaaacatct gtgaatggat cgtctacttg
    12541 gctacaggga aaatcactga attaaatacg aaccacaatg agattttcta aactgaagtt
    12601 gtgattctgc tgtttattta ggaaaagagg ttgtgaaatc agcgttttgt cctgagtatt
    12661 agagaaacaa acggtaaaat agttcctcat attttgccgt tttttgagct aataccgaag
    12721 gtcagctgat tgaacaccgt ttattctgga aaagggtttg tgacaaaaca tgtcacaaac
    12781 ccttttcatt attccaatag aaaggataaa gaatgcaaaa aaagattagc atcatcatca
    12841 ctctattttt tatttgtata cttgcttcat ggtttattca gcgtcaagct gctctatatg
    12901 acgtacctgt catcgagatc gaaagagtga gaatagaaga ggatcaacaa ttgattacag
    12961 gaagattgat gaatacggac caaaaaggag aagtgatttc tttaacggct ccttatcaaa
    13021 aaaatcaaat cgaaacagca aatataacaa caagacaaat ctatcttgtc caaatgcatg
    13081 gagatgaatg gcaactagta gcaaaaaaaa atgatggctg gctttttttc tttacaagtg
    13141 tcttcattgg caccatgttg cttattggtg gaaaacaggg cgtatttgct ttaggaagtc
    13201 tcatcatcaa catcgtttta cttttacttt tgttgctcct ctttaccaaa acagaaggta
    13261 tttctctctt aaatatagca atcttatttg tcgttatagg gataatcgtt agtatattgg
    13321 cgttagacgg atggaataga agcagtataa tcaaaatttc ggctgcagtt acaagtgttt
    13381 ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagatcaa ggactgcgct
    13441 atgaagaact gaattatctg acacgaccgt atcgttctgt ttttctttcc agcgtgctga
    13501 ttgggacagc tggagggaca ctcgataccg tgatcacagt cattgcgaca ttagaagaat
    13561 tgaccaagca acaaccgaaa atatcagcga aacagttatg gctttcagga aggcaagtgg
    13621 gccgagatgt gattggttcg atggctaata tccttttatt cgtctatatc agcggagcga
    13681 ttccatcgct tctgttatat ttaggaaatc aatggtcttt caaagaaacg gtagaacgac
    13741 atttatcatt agaactttta cgcgtcattg ctggcagctt aggaatagta ttatcaatcc
    13801 ccatcgcggt cctctttttt ctcgctgtaa ggaggttaaa aaaatgaatg tacttattat
    13861 acttgttggg atttttgcaa tcagtgtgct atttgtcggt ggtacgcaag gtatgtatat
    13921 tcttttagga ttattcatta atttaggaat ctttttccta ttattattcg gctatcatca
    13981 gaagtggccg atattggtat tgtcgattat agggttccta ttgatcgctg tggttatctt
    14041 attttttatc aatggttata atctgaaaat gcgagccgct tttgccagta tactgatctt
    14101 tttgttttgt ttcctactat tgattcctat cactgatttt ttagcgatcc aaggctttac
    14161 ttcgatagaa ctagaagaac tatctggctt agataagacg ttagcaattg attttagact
    14221 acttacgagg tcgttgcttc tgatcagtct tagcggagct gttttagatg cgagtgtagc
    14281 gatttctagt ggaacattcg aagtatatca ggcaaatccg caaatgtctt ttaaccaatt
    14341 gcgccatgct agctttgcca ttgctaaaaa aatattggca tcaacagtga tgacgcttct
    14401 ttttgcgttt atggggagtt ctttagcgtt gattctttgg tttattgact tagacatttc
    14461 ttttcagcaa ataatcaatg aaaaatcatt tgtcttggaa tatacgatgg ctattcttac
    14521 cacactggcc gcactacttg tcctgccctt aacttgcgtg actacagcat atctctttac
    14581 aaaaaagaaa gaacatctca agatggagta aaagttacaa cttaagtcct atgacatttt
    14641 tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt tgcttaagga
    14701 ggcaatttcc atgaaagaaa gagaacgtat tttagactta gtgaaaaaag gaatcctttc
    14761 gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg aaaaacaaat
    14821 caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagatcagg caagtcaatt
    14881 gatcgatgaa cttgaaaaca gtgaagaaaa aatttctgag ccagttgatc caaaagaaaa
    14941 agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa ctgaagcgaa
    15001 taaaacttcg gcgcgtctag acgaagtaaa tgctcaattc gctgacaata aggcagcacg
    15061 taatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag gcgagttgac
    15121 agaagaagaa ttagcacagc gtcaaacgtt agaagcagaa atcaaagagt tagaagcaac
    15181 cggcgataca ctattagaag aacaattgaa gctggaagca gaattaaaag atatccgcaa
    15241 gaatcaatgg tctgagaaaa aagaaacatt tacggataag tttgaattgc cagatgattg
    15301 gaaagatcaa gcgacagata cgctgaatca agtaggcgaa aaaatgtcag aagctggatc
    15361 acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag taaatgataa
    15421 catggaatgg aaagatgtca gcttacgcgt ccctggaatt gcgacaacga aatttgaaca
    15481 cgaattttat tatgaagctc ctgcagcaag tatccttgat atcaaggcag caaacggaaa
    15541 cgtgacgtta aaaacgtggg acagtgatga tgtgaaagtg gaagccaaga tcaaacttta
    15601 cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga tcgaggtcaa
    15661 tgaagatcat atctccttcc aaattccaaa taagcgtgtg cgtgcagacc ttgttttcta
    15721 cttgcctaaa cgagtatacg accatgcagc tatcaaactt ctaaatggca acatcatgat
    15781 tgagacattg gaagctaaag atatttatac aaaatctacg aatgggaaca tcatcgtgaa
    15841 ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg atattcgaaa
    15901 cgggaacatc ttagattcta ttatagaaac agtaaacggt acagtgacat ttggtgccac
    15961 accagaaaac ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga ttaaagaaga
    16021 taatttgaaa aaagtagaag caagttcagt gaacgggaat gtcaaagttg ctttaccaga
    16081 tagcatcggt ttggaaggac acgctaaaac aagtcttgga agcattaaca gccgtctgtc
    16141 caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc aattccgtcg
    16201 tgtttcagat gatgagatcg cacaagtgca gctttcaacg acaacaggaa gtatctattt
    16261 aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag caataagaag
    16321 cgatttttta aaatagcttc ccctatttta aaaaaatgtg ccttattgcc gataggctat
    16381 ctcttgaaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt aaaatagtag
    16441 aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc caataaaaat gttgttttga
    16501 caggtacttt agcagggatt ggggaatata tcgggattga tcccactgtt atccgtgtgc
    16561 tttatgtatt cttaagctta gttgcttttg gaagtccaat cattttatac attttattag
    16621 ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac aatgcatatt
    16681 atgaaaaaaa caattatcgt gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg
    16741 atgacgaatg gagtgacttt taatgtcgta ctttcagcgt attttggtta atacgttaac
    16801 attcatatcg ttggctgttc tttttcctgc gatggtccat gtgagcagta tttggacggc
    16861 cgtccttgcc agcttcgtat tatctgtgtt gaacatgttt gtcaaaccga ttttgacgat
    16921 cctgtccctg ccctttacat tagtcacatt gggattgttt acgtttgtta tcaatgcagc
    16981 gattcttaaa atgacttcct tttttgtagg agcagaacat tttagttttt cttcatttgg
    17041 tgcagcgtta ttcgtagcta tcttgatgtc acttgtcaat gtaattgtta gtgaacataa
    17101 cagcagaaaa taaaaaaagc tgtgccgaga tctcggcgca gcttttttgt ttagaataaa
    17161 gaatgcgttt tctattacat tggtaattaa ataaaaacgt tttttttaat tggtagtact
    17221 tttggctaga caatgataaa atgatagaga acactctaat agaaatgagg tagcatgaat
    17281 gtcagaagtt gtaaaagtta gccaattagt aaaaaaatta tctttggaaa tcgtcacagg
    17341 cgacgagaaa agtttagacc gcgtcatcgt gactggggac atctcacgcc caggactaga
    17401 gttgaccggt tattttaatt attattccca taatcgttta cagctatttg gcagtaaaga
    17461 aatcagtttt gcggaacgga tgatcccaga agagcgtttg atcattatga gaagattatg
    17521 tagtgaagat atgcccgcat ttattatttc aagaggattg ccggctccgg aagaaatgat
    17581 ccaagcagcc aatgaaaatg ggatagctgt gctgcgttcg cctatctcaa cgtcccggct
    17641 gctaggtgaa ttatctagtt atttagatgg acgcttagcc cctcgaacaa gtgtccacgg
    17701 tgtgttagtc gatgtctacg gattaggtgt actaattcaa ggggacagtg ggatagggaa
    17761 aagtgaaacg gcgttggaac tgattaagcg cggacatcga ttgatcgcag acgatcgagt
    17821 agatgtctat cagcaagatg aactgacggt aatcggagaa cctcctaaaa tcctggaaca
    17881 tctgattgag attcgaggga tcggtatcat agatgtaatg aatcttttcg gtgcgagtgc
    17941 ggtacgaggc tctatgcaag tccagttagc tgtttatcta gaagcatggg cgaaagataa
    18001 gaaatacgac cgtctgggct ctgaagacac gaccgttgaa atcgcggaag tgggcattcc
    18061 acaaataaaa atccctgtca aaacaggacg aaacgttgca atcatcattg aagtagccgc
    18121 aatgaatttc cgcgcacgta caatgggctt tgacgcaacg aaaacatttg aagaaagatt
    18181 aagtcgcttg attgaagaaa actcaggcaa tgactagcaa ggagtgacaa tatgttagca
    18241 caaatcaatc gagttgcttt tgagcttgta ggaattccta tctactggta tgcattgatt
    18301 atcgtatcag gaatcattat tgccatgtgg ctcagcagca gagaagctgt tcgggtagga
    18361 ttaaaagcag atgacgtgac agattttatg ttgtggggat tgccgatttc cattattggt
    18421 gcccgcttgt attatgtttt attcgatctt ccccaatata tagctgatcc aatccagata
    18481 ttcaatatcc gttcaggagg attagcgatt tacgggggat tgattgcagg tgcaatcaca
    18541 ctgtactttt ttaccaaata tcattttatt tctttgtgga cctttttaga tatcgctgca
    18601 ccaagcgtat tattggcgca ggcaatcgga cgatggggaa atttcatgaa ccacgaagcg
    18661 tatggtccag acacgacacg aagtttctta gaaagtctgc atttaccgca attcatcatt
    18721 gataacatgt atatcgaagg aatctatcga caaccaacct ttctttatga atcactttgg
    18781 agtttgattg gatttattct gcttttggtt ttgcggaaga aaccacatct tttgaaaaaa
    18841 ggagaagtcc ttttatgtta tctaatgtgg tatagtttcg gacgtttctt tatcgaaggg
    18901 ttacgcacag acagccttta ctttttaggt gtgatccgca tttctcaatt attgtctgct
    18961 gttttatttg tcggcacatt gattctgttt atttggcgta gaaaaaaagg aagtttaccg
    19021 gattatgacc gctcattagg aaaaaatcaa caaattattt gattttcaga gcgttaaaaa
    19081 tgaaaaaaat ttcaggagtg gtaaaatgaa ttatagagta gcggttttag gaccaggctc
    19141 ttgggggact gctttagcac aagtcctcgc tgaaaacgga catgacgttc ggatttgggg
    19201 acatcgtgct tcacaagtag aagaaatcaa cacccaacac accaatcaac gttatttacc
    19261 agatcatcat ctacccgatt ccatccgagc attcaccgat atggaagatg cagtaaaaga
    19321 tgcagatgcg gtactattcg ttatcccgac gaaagcgata cgttctgttg caaaagaact
    19381 agttgccaaa ttgaatacga agccagtgat catccacgca agtaagggat tagaacaggg
    19441 aacgcataaa agaatctctg aaatcttgtt agaggaaatc ccgacagaaa aaagaaaagc
    19501 tgttgctgtt ctttctgggc caagccatgc ggaagaagta gcaaagcatg acattacgac
    19561 gatcacagcg gcaagcacaa atgtaaaagc agcaaaatat gtacaagagc tgttcatgaa
    19621 ccattatttt cgaatctata ccaaccctga tgtgattggt gtagagatgg gagcagcttt
    19681 gaaaaatatt attgccattg gagctggtgc tattcacggc ttagggtttg gcgataatgc
    19741 aaaagcggca atcatgacgc gcggattagc tgagatcagc cgtttaggtg tagcaatggg
    19801 tgccaacccg ctgaccttta ttggcttaag cggagtaggt gatctagtcg ttacttgcac
    19861 aagtgttcat tccagaaact ggcgcgcagg caacttgtta ggacaaggtc agcctctaga
    19921 agaggtgcta gccaatatgg gaatggttgt tgaaggtgtg aatactactc aagcagcgat
    19981 ggaactagcc caaatgatgg aaatcgaaat gcccatcact caaacaatct atgaagtgct
    20041 gtatgaacaa aaagaaatca aaacagccgc aaaagaaatc atgttacgtg atgggaaaaa
    20101 agaaaatgaa ttctcattaa caattttttg aaggagcgaa tgtatatgaa agtaaaaaaa
    20161 gcagttattc cagcagcagg attaggaaca agatttttac cagcaacaaa ggcgatggca
    20221 aaggaaatgt tgccaatcgt ggacaaacca acgatccaat tcatcgttga agaagcgttg
    20281 aaatcaggaa tcgaagacat cttgatcgtt acaggaaaag ctaaacgacc aatcgaagat
    20341 cactttgatt caaatatcga attagaaaca aacctaagtg aaaaaggaaa aaccgaatta
    20401 ttgaaattag tagaagaaac gacagatgtc aatttgcatt tcatccgtca atctcatcca
    20461 aaggggttag gacacgccgt tcttcaagca agagccttta ttggaaatga accgtttgtc
    20521 gttatgctag gcgatgatat catggaagac gaagtaccat tgacacagca attgatcgat
    20581 gactatgagc gtacacacgc ttctacgatt gccgttatgc aagttcctca cgatgaaact
    20641 tcaaaatacg gaatcatcaa cccaggggaa gtactggaag atgggttata caatgtcaaa
    20701 aactttgttg aaaaaccaga tccaagcaaa gcaccaagtg atttagctat tattgggcgt
    20761 tacttattga ctccagaaat ctttgatgta ttatcagaac aacaaccagg cgctggaaat
    20821 gagatccaac taactgacgc aatcgatacg ttgaataaaa cacaacgcgt atttgcccgt
    20881 aaattcacag gtaaacgtta tgacgttggt gacaaatttg gttttatgaa aacaagtatt
    20941 gaatatggtc tgacacatcc agaagtaggg gcacctttgc gtgaatacat catgtcttta
    21001 ggtaaaacat tagaagcaga aggaagcaag atcaatcata atccaaaagg aataacagaa
    21061 atcaaagaag aaaagaaaaa ataatctttt tttctaacga gcttcagctg ctaattgaat
    21121 aaaaagtagt tgaagctcgt ttttatttgt ttaaaaaaca cgaaaatgct atccttatag
    21181 aaaagagaga caagaaggga gtttgatcat gtcaggagga gaaattgcag gattgatcgc
    21241 agcaatcgcc tttgcgatac ttgtcgtttt catcgttcgc gtattgttgc aagtttccaa
    21301 aactttagaa aaagtagacc agactgtcgc agaagcaaat acgacaattg agatcgtcac
    21361 acaagacgta gatcttttat ctagacaagt agaaggcttg ctagtcaaaa gtaatgagct
    21421 gctcttggat atcaatggaa aagtcgcaac gatcgatcca ttgttcacag cagttgctga
    21481 tttaagtgaa agtgtatcgg aacttaatca ttctagtaaa aacatcgtga cgaaagtcgg
    21541 cggaatcgga aaaacgacag ctaaagcgac tgttgccgga aaagtcggtg gaacagcgat
    21601 gaaattttta aaaacaaaaa acatactgaa acgacaggag gaaaataaga atggctaaaa
    21661 aaggtggatt tttattaggt gcagtagttg gaggtacagc cgcagcaatc gccgcattat
    21721 tgttagcacc caaatctggt aaagaacttc gggatgaatt ggctgctcaa gcagatgatt
    21781 tgatggacat ggcttcagat tacacagata tggcaaaaga aaaatcatct gagttaacag
    21841 gtattgcaaa agaaaaagcg caagatcttt ctcaacaagc aggggatcta gcaggcaatg
    21901 ttaagcagaa ggtaagtgaa tcagcagagg aagcaggaag cgaatcagat gatatcttgt
    21961 taaacctcaa agaacaatca gctgatttat ctaatcgttt caaaaaaaca gcagaagatc
    22021 tgaaaaagcc agcagacgaa ttaggtagta ttgctaaaga tacttcagaa gatatcatga
    22081 tcgatgtaaa agatgctgca gataaagcag gagagacggt caatgaagga atgtcagaag
    22141 caaaaccagt tgcagatgac acaaaagaaa tgttgaaaat ggcaaaagaa gatgcaaaag
    22201 aagctaaaaa agaaatgaaa gatacaatga cagattcgac taccaatcac taagattact
    22261 catttctag
//
LOCUS       DBGZHO010000045        22060 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.045, whole genome shotgun sequence.
ACCESSION   DBGZHO010000045 DBGZHO010000000
VERSION     DBGZHO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.045"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(57..104)
                     /locus_tag="ACN3HL_001915"
                     /pseudo
     CDS             complement(57..104)
                     /locus_tag="ACN3HL_001915"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(418..1332)
                     /locus_tag="ACN3HL_001916"
     CDS             complement(418..1332)
                     /locus_tag="ACN3HL_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8006772.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(1347..2348)
                     /locus_tag="ACN3HL_001917"
     CDS             complement(1347..2348)
                     /locus_tag="ACN3HL_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HHC8006773.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            complement(2345..4528)
                     /locus_tag="ACN3HL_001918"
     CDS             complement(2345..4528)
                     /locus_tag="ACN3HL_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HHC8006774.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            complement(4531..6978)
                     /locus_tag="ACN3HL_001919"
     CDS             complement(4531..6978)
                     /locus_tag="ACN3HL_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006775.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(6962..7354)
                     /locus_tag="ACN3HL_001920"
     CDS             complement(6962..7354)
                     /locus_tag="ACN3HL_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8006776.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            complement(7441..7938)
                     /locus_tag="ACN3HL_001921"
     CDS             complement(7441..7938)
                     /locus_tag="ACN3HL_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHC8006777.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(8055..8279)
                     /locus_tag="ACN3HL_001922"
     CDS             complement(8055..8279)
                     /locus_tag="ACN3HL_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006778.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001923"
     CDS             complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="ACN3HL_001923"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HHC8006779.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11077..12282)
                     /gene="mobT"
                     /locus_tag="ACN3HL_001924"
     CDS             complement(11077..12282)
                     /gene="mobT"
                     /locus_tag="ACN3HL_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HHC8006780.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(12305..12458)
                     /locus_tag="ACN3HL_001925"
                     /pseudo
     CDS             complement(12305..12458)
                     /locus_tag="ACN3HL_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(12461..13846)
                     /locus_tag="ACN3HL_001926"
     CDS             complement(12461..13846)
                     /locus_tag="ACN3HL_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HHC8006781.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(13875..14261)
                     /locus_tag="ACN3HL_001927"
     CDS             complement(13875..14261)
                     /locus_tag="ACN3HL_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8006782.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(14277..14591)
                     /locus_tag="ACN3HL_001928"
     CDS             complement(14277..14591)
                     /locus_tag="ACN3HL_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8006783.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="ACN3HL_001929"
     CDS             complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="ACN3HL_001929"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HHC8006784.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15851..17140
                     /locus_tag="ACN3HL_001930"
     CDS             15851..17140
                     /locus_tag="ACN3HL_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HHC8006785.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(17179..17784)
                     /gene="ytpR"
                     /locus_tag="ACN3HL_001931"
     CDS             complement(17179..17784)
                     /gene="ytpR"
                     /locus_tag="ACN3HL_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HHC8006786.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(17980..18444)
                     /locus_tag="ACN3HL_001932"
     CDS             complement(17980..18444)
                     /locus_tag="ACN3HL_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHC8006787.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(18466..18786)
                     /locus_tag="ACN3HL_001933"
     CDS             complement(18466..18786)
                     /locus_tag="ACN3HL_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HHC8006788.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="ACN3HL_001934"
     CDS             complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="ACN3HL_001934"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HHC8006789.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20208..20558
                     /locus_tag="ACN3HL_001935"
     CDS             20208..20558
                     /locus_tag="ACN3HL_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HHC8006790.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            20743..21696
                     /locus_tag="ACN3HL_001936"
     CDS             20743..21696
                     /locus_tag="ACN3HL_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HHC8006791.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            21709..>22060
                     /locus_tag="ACN3HL_001937"
     CDS             21709..>22060
                     /locus_tag="ACN3HL_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006792.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSF"
BASE COUNT         6221 a         4527 c         4052 g         7260 t
ORIGIN      
        1 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
       61 aagcccaaaa gggcataaaa atcccagtga taaatactct tatcactggg atttttatgc
      121 ataaccatag gcatacaaag catacagata ttctccggat actttagaat cacatgataa
      181 aggtattctt aaactgggtg caaaaaacta agccctccta aaaaaggaca tccaattatt
      241 tgttcccact atcaaattga cagtttattt aagaatacct tgccgcatat ttattaactc
      301 cttttaaata gatacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
      361 tttttatcaa agagagtacg tgattacaaa atagctgtaa taatgtacca atatttgtta
      421 ttctataatc ttccaattac tcccgttctt ttcaagtacc aaatcaaatt gagatacctg
      481 cgttgctttg gtctgctggt cgatatactc cactgtcagc gataccgtga cttgattatc
      541 cttacgattg taaataggat ttaccagttc ttgaaagatg tactcttttc cgattggttt
      601 taatatcccg tcattcacat agtaggaaag ttcactggct gtcgctgtag gatagagctt
      661 gaagaacgtc gttaaaaact cattgatttc attggttgta atggaatcaa ccgtaccctc
      721 actttcaata gcttttggtt tatagtctga tttctttggt atgctagtaa tggtcggatt
      781 cttaatgagg accatatttc cagtactgtc tacatagaca ctcactatat aagcagagtg
      841 gacggtcttt gtattttccc cctctgtaat gagttggtct acactgtagg ttacatcaaa
      901 ttgattgtcg ccatctgctt ctaccgtcca tatctgaaat ccttttacag aagacgatac
      961 aggaatatct ttacgaactg tatcgacatt cagagcttga agttcctctg tcagatatgc
     1021 tttcaggttt tctatgcgat tatcaatgga cttgtcgttt agttcccatg aatagtagac
     1081 tttcgcaaag ttctctacaa aattttccac atgatgagta tcgacatatt ccttttctat
     1141 gatggtggtt tcatgaatgg tatgggtatc aatggctgta aagtgcttga atatcgcaaa
     1201 gctgaaacta agtcctaaaa gtacccatag gacaatcaca acctttttac gaggattgac
     1261 cttatagaca cgaggtttct tttcctttgg tgtctgtttt tctgtattct gattttttcc
     1321 gaatttcatc attgaatcgt cctttcttat tgtttgattc gtcctgctcc cactaaatgc
     1381 tgttgccagt aagagcttgt taagtcggca taaccgatag ggtcgcctgc atgaaacata
     1441 cggttatcgc ctaaataaat cccgatatga gtaatataag agccagcgtt ataggtagaa
     1501 tgaaagaaaa ccaaatcgcc ggcttttgct tccaataatg ggatatgccg ggttacatca
     1561 tattgctgtt gtgctgttcg tggtaagttg attccagctt ttccatacgt ccattgtgtc
     1621 agtccgctac aatcaaaaga ggtagtcggg gaagctccgc catagacata cttccagcct
     1681 tcaaatttca gagcttcgtc catgatggct tgtactgtat catcatcaaa ctctgttgtg
     1741 acaagatact gcgttaccag ttgcacataa aacatattcc cgtaattgta tcgccagccc
     1801 ccattgatag gtatggctat gggattgggg taagacactt tttcgtcacc cgaatactct
     1861 tttgagaaac tttgagccag ttcaaaggta tatttattcc cacgattagc cacatatcct
     1921 aagaaaccac caccataatt gtaggactgg ataaccgatt ctaaatctac accaagcctt
     1981 tcgctactgg ctaataactc actgaaatac ttcacacctt gcttaatgga ttcttctgta
     2041 ctcaatgaat taggtggaag accgagggat tccgaggact gcataacatc ttctgctgta
     2101 ccacccgatt ccacctgtat aatcgcaaga agtatattga cgtattcttc aattccatat
     2161 tctttggcaa ctttttctac cataggctta tgagccagca cttctgcgga aacatccaca
     2221 ccgccatagt gaatgttgga aaaaccgcca tcttgttcat ctgaaaataa aatggcgaca
     2281 aacagaagca gtgagaagac catcaagaat aatcccgaac caccaatcac taaagttttc
     2341 agcttcatgg tttcttactg cctttcttaa tggtggcggt tttgattggt ggtctacttt
     2401 ttgtattttg tagtggtact ctttgaacag tagactgacg ttcttttgtg attgaacgtt
     2461 gtgaagctct atctgttggt gcagttgaag ttactggctt ttgaaccgtt ctttcttgaa
     2521 ctgtattact ttgacgttcc gtttttaaac ttgaagaatc ggacttaact gttggacgct
     2581 cttgtttggc ttgttgagat tccctatagg aagcctgtac agttgtttgc cttgaagtct
     2641 gtccatcatg agattgttct tgcttagtgg ctggtctttc atgaacggaa gaagctggct
     2701 gttttttctg tttgacctgt tccatttcag agcgacgctc cgcaatggtt ttccgtcttt
     2761 gttcctgctg tttcttgcgt ccactggctt tatccgcttt ggtttgagaa atacttctgg
     2821 ttaaatcatg gacattatcc gtcactttag attttccttg atatactgca tatcttgcat
     2881 tggtcggcaa atccttaacc tgttctttca aattaccagc agtatctacc attctgtctt
     2941 tggtatcagc tactgtaccg atggtttgac cgatacgctt tcctagtgtt gatttttcct
     3001 gcccgtttgg tcgagagtga tctgcttgtg tactcgcaga acttcccgaa cccgactgtc
     3061 cttttttacc cgtagcactg gcaatggcag acccagcccc taaagcagtc acggagcgtc
     3121 caagtttccg ctgtagacgg tgcatgtgag cgtgcataag catacgaggt tttctcatca
     3181 tacgacttcc cacactttga gaatcgttac tctgtagaga aaacatactc attaaatcgc
     3241 ccagcttaaa gtagattcct gcaaaggtca caatctgtag aaaagcaatc aaaaagaacg
     3301 gataaccagc cgataaggta tagagcatgg ttgaaatact aaatgctgtc gtaataatca
     3361 atgtgattcc agctcgtgtc aaaatggtat taaagagctt tgttatggct cgttttgaca
     3421 taccatcaaa tgatggaatc atgcttaaaa taaagctcac aggcagaaac atagcataga
     3481 tgataaaaag tacctgcgag aaaatcatga ttcctgttaa taggaataca aatatggaaa
     3541 tcccaatatt gaagacaaat aggaagaaga ctgtacctaa acggttaatc gtctttgtaa
     3601 tcgtcatatt ggtattgctt ctatcttcaa tttcttccgc aacaattttt tctctgtctt
     3661 ccccattgtt ggaatctgga ctggttgaga gcaggctttc cacacggtca ataccaatac
     3721 tttcaatgtc tgaactgtta tattgaagca gtagccacgg ttgctgaacc tgtatggaaa
     3781 ataggctgtc acgtatcaag tccacactgt ccttgccttg actatctgaa tggggcatga
     3841 caatttttgt acccagtgac aaactagcgt tgctgatgtc tgatgaaaag tcattgattt
     3901 ttttaatgta gtcgggagcg taggcaataa aggaagccga taggataaaa accagcacaa
     3961 aattcatgag ggcatgaatt gcctttgtgg tttctctctt tatcagtcct gtataggcaa
     4021 cataaacccc aagaaccaaa atcaagagta aaaggaatcc aacatagaaa ccctctgttg
     4081 atagtccact aggcgtaacc cctgcaaggg tctgcatatt cttgccaatg gaatctgctg
     4141 tagcggaaat gaagtctaag gaataggctt cctgtactaa gtaacccgtc gcattggaaa
     4201 cataaagact gattgtccaa ataaaattgg taatggcata tagtccatac atgacttgtt
     4261 ttccaattcc gtccgaccag ttccacggta gccagcccca gctattatcc acataaaaat
     4321 ccagttgata gttttcaagt gggtatcggc tgtattcatt tgccacattg accgtatcat
     4381 ctaccaagcc cgcagcttga accaccgttc ccagcatggc taaaagaaaa atggcaatca
     4441 caagtgtgaa agccactgtc attgccactt tacctagacg tttcagcgtc cagtttgatt
     4501 ttattctgtt taatattgat ggtttcacat ttacacctct tttcgcacag gtggtctggt
     4561 atcaaaggca tggagcagtt cttcaaatac agggtggaac tgtatcacac cgacacgacc
     4621 atataaatca ctgataaggc attgcccgtt ttccaaatca cgcaatcgct tctgattgtt
     4681 ttcgtcctct gggtctacac caaaaaaggc aagggttttt ttaatctcgt taaggtcagt
     4741 ggaacgaaag gcaaatttta agccgaggtt atttttcagt ttttcatcta agaggtcatc
     4801 tgtattttgg gtcacgaaat ataccccagc gttcatagca cgaccagcac gaaccagctt
     4861 catagatagt gttttccctt gtgccacctg taagaagctc catgcttcgt ctaagtctac
     4921 aatcttgaaa atacttcggt ctgtatggat aaagtccaac gcaaaggtac taatgacaat
     4981 cagcattgct accgatagta actccattgt ggtatattcc tcaaaggaag tttccttgtc
     5041 aggaagtacc aagtcggcaa cctgtataat gttcagttgt ttttcaaggc tgatagactg
     5101 ctctacataa ccatcactaa aaagcagatg ggcaaagtca tagtctgtaa aactttcgat
     5161 atggtcggct atgctggtac ttagtggcgt attctcaacc cgtaattctt caatcacttt
     5221 catcaaccct cgcacttcac tattggttac tgcacgaatg gcttttctaa ggattgggaa
     5281 gcgttcccca tcacgagagg aaatccccgt aaggaatgtc aaaatatcaa tagccagtga
     5341 ttcagaatct ttggtatttt tcataattac ataagggtca agtaagcctt tgtttttctc
     5401 atcagaagtc agattgacga tattgatttc atgggaaatc tctggcaagg tttctttcca
     5461 tctgccacgt tctgcttttg ggtctacaat cactgcttgt gccccataaa gcactgcata
     5521 atagacgata aggttattcg caaaggattt accaccaccc agcgaaccga caaaggcaga
     5581 cgctaacgca ttggttactg aacccttaac cccttgactg gcaagagcag gtttcagata
     5641 gacattgcgt ccagtatcta agctgtagcc aacataaatc ccctcatttt cacccagcat
     5701 ttgagtagca ccaaaaccta aaccagcgag gaaatcagag gtcacgtatt gaatatagtc
     5761 attcatatat cttttgctgg caggtaaaaa ttcttcatgt aagcccagca tatccccaaa
     5821 aggtcgtacc agtttcacgc tcaaatcatc atagaaatct ttcacttcat tacaacgacg
     5881 tttaagttcg tcaaggtcat ttgctgatac ccttacaaca taggacagct tatacataga
     5941 ttccttgctt tggtctaaat tggtttccag ctcgttcaca ctttccagag cttccgccac
     6001 attagagctg gtttcattat cactttgcca agcgtggtta tccaagtctt tcagttcttt
     6061 ctttttattg cggacagtag atagggcttt acgattcgct acaatttcca cattcattga
     6121 cgtatcaatc ggaaaggtaa attgctgttg ctggtagtag aagatttcag aggacgggaa
     6181 gtccagttcg ccgacaatac tgttgatggt aaagtaagct acataggcgg tttcgtcttc
     6241 ctgctggatt ttcaaatatc gctgtttttc ttccaccaga cagcgagtag gcttaatgag
     6301 gtcataggtt ttaatcagtg tttcatgttc cagctttttc tttgatagag gatactcata
     6361 ctcttcatag gcagtgcctg tctgtccgta aaggtgttca atcagatagc cgaagtcatc
     6421 cttatctaat cttcggattt tgaaacgacg ggagatttta ttttctaaaa gcttttccat
     6481 cttctgaaaa cgcaggattt catcattact catactaaca aaatcgccca tcagcttatg
     6541 gttcacatca tagacaaaat cagtaaaagc attttttgct tcaacggtaa gacttttcat
     6601 agaaaactcc tgatcgttga gaagcaactt aaaaccgata aagaaacggt agtccacttg
     6661 attttcgcca atcatggata ttaaagcgtc tgtctgttgg tcgattttgt cataggcaac
     6721 cgttttgagc tttccagtga cttcattttt ggaacgttct tgtgcagaaa gtatgctgga
     6781 ttctgtactg atttgtaaag catgaatctt gccatcacga ttttgtgcga taagctgtct
     6841 gaaagaatca tgtacttgta ttttctgttc cggacttaga aatgagtaat tgtagggaac
     6901 aagctcatag taagcgtaac attccccatc tttattccag accagattgt tttcaatata
     6961 tttaattgga tatgccataa aattcactcc taactgctgt aatggcttct tgtggctggt
     7021 ttctgccaag cgttactttt tttcctgcat aggtcagctt tcgtcgcagt gcataagcaa
     7081 tgacagactt caaaaatcca taaggctttt taccatcaaa ggtttttgta gacataaacc
     7141 atgtgaaagc cacaggaatc ccaaagtatt tgagaaatgc tccctctatc atagaaagag
     7201 ggggcaagtt gccaagtatc ataactgcaa agagtgacac gacaaaccat gtcatttgcg
     7261 taaaggttat gggaaacgga agtctaaagt cattgatgga gtacaacact ttctcaacag
     7321 accagatact ggtatagctt cgtattttct tcatgtaatc aatcctttca taaaaatggg
     7381 gatagtcttt tgactacccc gtaaacaaga aaatctgcca gtaagaatgt accgacagat
     7441 ttaatagacg atttcaaaaa tcccgtgatt ggttgagata aacgttcccg aaaggtctaa
     7501 atcccgacca taggattcat aatcaatata gttttgaaga ctggctggca cttcgcctaa
     7561 agcacccgtt tcttcaatgt agtagcgtgc cacgtcagac atatcatcac aatcggaatg
     7621 aatgataata tcttcttgat gttcgcttag ttcttcaata cttgaaaaat gagtgagcag
     7681 agcagatagc tccgattgta gttcttctgg caactccgat accatttccc ataggcgatt
     7741 gagttcgcta atagaagtgt attcgtcaac cgtaaagggt aactcgtaat catgaatggc
     7801 gtattcctca tattcatcat tcaagccgat tttctctttg acttcctcaa agtcaatggg
     7861 aaaggtaaac cacgcaccga ccaattcgcc ctcattgtat ttgcctaaat tcgcaatata
     7921 gacttgcata tcgtccatat attcacgtcc tttctttgta gagattcaaa aatccctacc
     7981 gcacttcgtt tggtgtacca ttcctttgcg gaacataaga aaaccactta tattccacaa
     8041 aagaacggtt ttatttaagc accaataatg cgattgaata gctctagtaa aatgtctttt
     8101 actccagcag cgttgaagac taagccaacc gcaataatcg caataattaa aaagccaatc
     8161 agtttgctaa actcacgctt gaagccaaga tacaagccaa tcacaacgat tgctaaaagc
     8221 accagtgatt gagcgtttga tagaaaccag ttatatatgg ataggtaagt tcctgatatt
     8281 ataaatatct caaacttttc cccccattca cacggagcgt gcgactttca ccgcactccg
     8341 cgttccatcg tgtttatatt gaaaagtatt tatgtagtag acctatatca agtttaattc
     8401 ttgattgcca gctaatactc tatatttatt tagtcttatg agctggactt tatttagctt
     8461 caatagagct atatattttt gtattgtttc ttctgtttta gcgtgtatta gacggtgtac
     8521 cgcctctttt accaaaataa gatttttata atcgtcattt ccaccagctc cagttggtac
     8581 aatatgatga caatgtattt cattagcttg ttgaaattct tccagagtta tagcacattt
     8641 tccatgttga gcagaaaata gcgaaattcg attgtctgcg tattctattg tgcgattttc
     8701 caaagataat ttcattaact ggtacatcag taatttatca acacttagat tggtgtggat
     8761 aaattttctt ccctctagag tgtagcaatt cgctaaatac acctttgcca ttggttttct
     8821 gtgttggata tatccaacag ggaaaatagg ttcgccctcg ccagcaacat accgaagcat
     8881 tttagattta ccatatcttg ttgcctcctt tgtcgtaagt tgtctgcctg tttttctcaa
     8941 tctgcccctt ttgtttgtac ctaatctgtt agtgaagata gccattacag ctctattcag
     9001 tttcatacaa tccagattta cattcgttgc aatctgataa taattttgca tacctaatac
     9061 cattgaatta taaagtcttg tttcttctaa ttccgttttc ccttttgagg gagaagcaat
     9121 tttctttgcc tgtgatacca gcttgtcttt ttggtttttg aattgtttat cacttatatg
     9181 tgatttaaca actaacttct ttcttctcgg tatcatttta atcttgaaac caagaaagtc
     9241 ggagtatctt tttctaacat ttacaattct tgttttttct tgtgatactt ccaattttaa
     9301 tcgttgttca atccattgag tgattgctat tttggctttt tcagcacttt ccttgtagcg
     9361 gcagaaaact ctaaaatcat ctgcataacg aaccatatac atttccttta actttgtttt
     9421 cttcatttct ttgtaagcgt tgcttttaca tgggctaccg cttttattga tatgaaccac
     9481 atagtttttt gtaacaggat tttcctgcca ttggctttct acccaatggt ctaactcatt
     9541 aagaacaatg tttgctagta gtggggatat tattccccct tgcggagttc ctttctctgg
     9601 atatgttatt gtaccgttag tcattttgat tggagctttt aatatccttt ttaaaatgaa
     9661 tatcaagtgc ttgtcccgta ttcccatagc ccatatctgt tttatcagct tggaatggtt
     9721 cacgttgtca aagaaaccct taatatcaaa ttcaatcaca taatgtagct ggctgatttg
     9781 taggcggtta taggttgctt ttattgcatt ttcaactgac ctattaggtc taaaaccata
     9841 gctgttttca ctaaatttag cttcgcagat tggttctaat acttgtttta tacattgttg
     9901 tataagcctg tcccacatac aaggaatacc tagaggtctg gttttaccat ttggttttgg
     9961 tatttctttt cgcctcactg gcttaggtcg atacccatgt ggactgcctg caacaatgta
    10021 tcttactttt ttgacaactg tttctgctgg caatttgcca atatctttaa ttattgtacc
    10081 gtctgttcct gctgttttac tgcctgcatt tgctttgata tttcgatatg ccagtaatat
    10141 attttctctc gataggataa tatccataag atgagtgaaa atatctccat tcttactttt
    10201 ggcatataaa tcatcaaagg tgttttgcat ttcgtaatat tcagcgtgtc ttaaatcttc
    10261 tacacacaat gtttcatttt tatttttagg cataaggctt cactccttta cttgaaattg
    10321 agtgagcttt tttatcttac tcgtaatcct tattgaaaca acataatact tttctaatat
    10381 atacacgact tgagggcatt cctccattct cattacaaga atttcttagg ttcgccctct
    10441 gcttttcagc attagttcaa ctgcttattg ttcttcgtca gtttattctc ttgatgagaa
    10501 cccaatacct ttcctcgttc cgataatctt atctatacat atatatcctt aggtcactag
    10561 ctataagcct gctggcttga taccgcctgt aacgttatat ggcatttcat aacctatatt
    10621 cttactttgc cacaccagct acgatttctc gtacctttgc atttctacaa agttcaaatt
    10681 tagacccgta cattcgctgt ttcgtcagtt ccttatagaa cattctaacc atagatattt
    10741 tatagacccc cgacctgttg gatacgctac ccacctctgg atagttttcg atagaagata
    10801 tatgttcatc aactattacg gtatctttca gccgtcttta ccgagcttca aacattctga
    10861 gtttcctcat acaatgcttg tcggaggctc agggcaggcg tttcagagcg ttacttcatc
    10921 attccacctg tcagattatc agttctccta ataaccaaac tttttcgttc ttttattagt
    10981 gccttagctt ttcactaagg aacgagtcgc acaaaggttt tgtccaaaat tcataaaaat
    11041 gttctcctct ctatattcaa tgaatttgta tttgagttat ttttttgttg ttatcacgtc
    11101 ctgttctttt actgactgtt gcttcaaaat ctgcttgtgt cggtctgtca gtttcgcatg
    11161 gtcgagaatg tcttttacaa cctgcgtctg gttgatttca tcaagtttaa tcgcaacctt
    11221 taaggtcggg gcaacttgat gagatagcca gttcagcgtc ctttggaagg agtaaggctc
    11281 tggttttgtg gttagtttta atcgttcacg attgttccca ataaaccaag cccattcttc
    11341 attcagtttc caatcagaac gaggtttgga atcgtcttta tctacaaaac ggatataccg
    11401 attgataatt ttaaaggcgg tatgctctgg attgtcatag acgagtaaat cacggactgc
    11461 ataataggca cgctcatttt tcaatcgaat ctcaaaacgg ttttttactt ctgcgtcttc
    11521 aatgggaata tcatttttct tgtactgctc gtagtccttt tcatagatac agaaataaac
    11581 ttcactttgt aatgaaccga tatagagggt gtttcccata cattcctttt cctctttgcg
    11641 taccagttcg ccactgcgat agcttttaaa actgcggaag acggagatac attcttcctg
    11701 ttggcacttt tcagtgagta cagggatatt taaaatccct gtcttatcgt taatggcaag
    11761 gtcaaggcgt ttcatcacac cgccagccac caaaacgtcc ataaagaact cataccagct
    11821 tctttgttgt gccagaagat agctttcaaa ttgtctgcac ccacgacctt tcaattccac
    11881 cagaactcct ttgtccagtt catgggagca aaggacgaat atgtcgccta aagcataatg
    11941 ctctgaataa gaatagaaac catagtcctc atgaagaaaa taggacagtt tcagttgtaa
    12001 gatgttttcg accacctgct gtacgtctgt tgtcggaaag cgaattctta cataatcaaa
    12061 cagcatttca aggggagcgt cgggattgaa gcgttccaga gcttcccaaa gggactgctg
    12121 taaatcctct gatggcttga cttttcctgt ttcaatatcg cttagatact gccttgtaat
    12181 accagtcgca acagctaaac ggttttgaga tagtccataa gccaagcgtt tttcttttaa
    12241 atgctgtaac caagtttgtt cattcagtaa aaatccctcc aatcaaaaag gcgtatgtca
    12301 acttttaaag cccatttgac atacgctgaa attttgtaaa tcccttgtaa ccaaaggatt
    12361 ttctaatgtt tttttgactg tttcctgtcg atttgtaccc ccctgttaga taccgagggg
    12421 ttaagtgctg gcgtggctat tgccacacca gccagcaaga tcagtccaca cctgcgactt
    12481 ccgcttcgca cgtcgcctgc gtggactgtc tgctgttgga taacttttta atttcctcca
    12541 agaaatcata tccttttggt acaaggggag tataaaactc tgatatgaca cttgttccta
    12601 catcaacata gccacgacct ttgattcgct ttaagaagaa atccttttgt acgtcactgc
    12661 caaacatcat gccatagccc atttcagaca tacgacctaa agccactctg aaattaaact
    12721 gatcacggat tccgtcgcct aaatattttg cgtctggacg ttgacaagcc agtattagaa
    12781 agaagccagc ttgacgacct aacatgacaa tctgtttcag cttattcata actgcggtgt
    12841 tttcttttgt tcccagcatt tccatgaaag cgacgtattc atcaaagatt aagaagtgtg
    12901 ccgggagacc taagtaagca taatttttgc cagtcttata gttcttcatc tgcttcattt
    12961 cctcactacg tttcatcatt tcttcataga atgtttcaat gcaagaaagc aagtcttctt
    13021 ttctatagta gacatttgcc atcacagaac ctaagtccgc aaggtcagca tttttcgggt
    13081 caagaatata cagttttgaa tctgtatgaa gcaaggcttc aatcagtgtc agtataaagt
    13141 aagttttacc gccacctgta ccaccagcaa tcaacatatg agggagctta tcatattccc
    13201 accatacgtt tttcattaag cgaagtttac catctttagc ttctacttca tcaatagaaa
    13261 tacgactggc tatggtgtca tagagcaaag tatattccac ataggaatcc tttaactctt
    13321 tatccgtcag ctcacagtac aagccactct ctaatttctt ttccaagtgt aagagttggt
    13381 cttgatattt tcccagcgtg atttccaccc gtatctgtat caagccattt ttaagtcgat
    13441 aatacatttt agggaagtag gttatctttt cctttgtacg accagcacta tctttaaaga
    13501 aaccctctgt tttgacctgt tcagattcat accacttgtt ttcaagtatc atctttgcca
    13561 gtttttgacg gtggtaaagt tgtttaaccg tatcatagcg aacccgtttg aatacaaacg
    13621 ctaccagcaa gcagataaga attgcgacac tgaaactgat aattaaatag ggaatgtcaa
    13681 tcttatctgc ttgtgatagg ttaaaatcct gccagttgat ctgctggatt gtcttcacat
    13741 gaaacagtcc gacaaccagc aggaaaacag gcaggagtga cgctatcgta aaatgaaaga
    13801 ctaaatcttt accagatggg cgaatccttt taccacgctg tttcatgcga aaaagtctcc
    13861 tttctaccta gcgactattt gtcttgtgtc ggttctttct ttgcttgtgg ttgagctttg
    13921 aatgaactag aatcctttgt cagcacaata tcgtctgcct tgatatacca gtcaacatct
    13981 gctccttgat aggtggcagt agcaacggtg tccgcaatgg gattgataag ttccacccgt
    14041 gcgttataat caaactcttt caaaggcacg ctggcaggaa tacttacttg aatcatgcgt
    14101 ccttgtcctt tggattttaa gtcataggta cgttccttga tttcatctga aaccgacccg
    14161 tcttcatttt ggattctcac ttcacgacgt agagcagaga atttcaattc tccaaaagtc
    14221 gtgtctttat ctaatacaat gccatttgct aatctcatca tttttcctct ctttctttat
    14281 tcttttatca tgtcgtcagc atgtaaaagg taatttgtaa aaccacgagt gccgattttg
    14341 tagccctctg cggtaatacg tggattgact aacttcacac gttcctcaaa gccgaaatgt
    14401 ttttcgccag cttcagcagg aagcaccacc acaatatcat ctgctctttg aacatcagaa
    14461 tagagattat agcttcttga taagacagtt agccgtccgt tgattcttcg ctgaacgact
    14521 ttatcctcgc cagcaaattc taaattgccg aatgtttttt ccatgttggg aatcacaaat
    14581 ttaagttcca tatttttacc tatcctttct tttttattgg ctgaatgaat gtttgatggt
    14641 cttaaagagt ggggaacgac cttttgattc ttgatttttt gttttcataa gttcacttcc
    14701 tttcaaaatc gggtaaaaaa atagacacct cattttttga agtgtctacc tattaaatat
    14761 tcaaatttta ttggaagtat ctttatatct tcacttttca aggataaatc gtcgtatcaa
    14821 agctcattca taagtagtaa attagtagta aattgagtgg ttttgacctt gataaagtgt
    14881 gataagtcca gtttttatgc ggataactag atttttatgc tatttttctc ttaaaaaata
    14941 tcattatttg tggtatggag cccccgcgtt gatccggaag gcacggtaga tttgctcgac
    15001 gaggatcagg cgcatcaatt gatgtggata cgtcattttg ccaaaagaga tctgagcatt
    15061 gcttcttttc atgacggctt cgctgagtcc taaagaaccg ccgataacaa aaacaaggtg
    15121 gctttttcct tggataccta attggtcgat ttgtttagca aaagattcgc ttgtgggatt
    15181 tttcccttca attgctaagc catagacgta ttcttgttct ttgattttcg ctaagatccg
    15241 ttctccttct ttttctttta cttgtctcat ttgcgcttcg cttaaattct ccggggcttt
    15301 ttcgtcagga acttcgatca attcgatttt cgcataggca ttcagccgtt tgacatactc
    15361 attgatacct tggatcaagt atttttcttt taattttcct actgaaataa ttttgatatt
    15421 catgttttct ctcctttgat cttcacgctc actttgttta ttataatcaa ttttttcgtc
    15481 tatatgttta ttttgactat ttttgttaaa aagatttccc caacagttat gcacaacatc
    15541 cacaggttta tccacagaaa acagcgttgt tttaccttat ttcatcacat tcattaggca
    15601 aacatacgtt ttataagaat ttatccactt tatacacagg ctgtggatat gttttatccc
    15661 ttatttttcc aatcctatcc gcgtagtttt acacaatatc tgtggaaaaa gaaaatcaaa
    15721 tattttcatc tgaaaacaat gatttttcct aaagtttttc ataaaaagtt caaagtctca
    15781 aagtagacta aagtcaacaa ataagactat actaacagta gataaatgaa tgtaattgga
    15841 ggaggaacac atggatagaa aaaatgtgac accaaagatg aaaaaaaata aaaataatag
    15901 cctctggcgt aagttgggtc tggggcttgt tggagggatc gttggaggac tactgacagc
    15961 tggcattttt tatgcagcga tgggcactgg caacaatagt tctactgcta caagcggcaa
    16021 tcaaaattct gccggtgaaa cagttgtgga aaatgtcaaa gtcaatgtag attctgatat
    16081 caccaaagcg gtagataaag ttcaagacgc tgtcgtttct gttatcaact tacaaagtca
    16141 aaaccaatca agcggttttg gcggattatt cgggcagcaa gaagaaagta gcagctcaga
    16201 tgatagtaat ttggaagctt atagtgaagg aagcggcgta atctacaaaa aagacgggaa
    16261 tactgcttat gtagtcacaa acaatcacgt agtagatgga cagcaaggtt tggaagtcat
    16321 gatgaaagac ggtacgaagg taaaagctga attagttgga acagatgcct attcagattt
    16381 agcggtgttg aagatcaatt cagacaaagt cgaaacggtt gcctcttttg gggactcaag
    16441 tgctttgaag gttggtgaac ctgcgattgc gattggttcc ccattaggat ctgaatatgc
    16501 gaattctgtc acttcaggaa tcatttcttc cttgaaccga caagtaacaa gtacgaatga
    16561 atcgaacgaa acagtcaata tcaatgcgat ccaaacagat gcagcgatca acccgggaaa
    16621 ttctggtggt cctttagtga atatcgaagg acaagttatc ggtatcaact caagtaagat
    16681 cgcaagtact tctgaatcga cttctaatgt aagcgtagaa ggaatgggat ttgccatccc
    16741 aagtaacgat gtagtgaata tcatcaacca actggaaaaa gacggaaaag tgacacgtcc
    16801 agctctaggt atcacaatgg tcgacttatc tgccgtttct actcagcaac aagaacaaat
    16861 cttgaagatt ccttcatctg taactaacgg tgtcatcgtg acaaatgtcc aaacagctac
    16921 accggcagaa aaagctgggt tgaaacaata cgacgtcatt actaagatcg atgacaaaga
    16981 agtttcttct ggtgtagaac ttcaatctgc tttgtataag aaaaaagtgg gagattctgt
    17041 caaaatcact tactatgaag gctcgaaaga aaaaacaact actgttgaat tgacgatcga
    17101 tcaatcggca ttaaaacaaa atcaaaatag tgaaaattaa taaaaaagag gttgtgacaa
    17161 agacttgtca caacctcttt attttggaaa tacttctccg actacggcat cctcaggcaa
    17221 tactaagatt cctttttttt ctggagcatt tggcaaatgc aattcacgag cagaacaaat
    17281 cattccatag ctggctaccc ctcgcaaagt tcctggccag atcatcattc catctggcat
    17341 catggctcct ggttttgcaa cgacaacttt ttgtccagct tcgatatttg gtgcaccgca
    17401 aacaatttgc aatactgtcc cattgtccac ttctgtctca gtaatcgata aatggtcaga
    17461 gtcaggatgc gggacgcatg tttttacata cccgacaacg atcttcggtt catgatcagc
    17521 ttcaagctgt tcttcgaatc ctgcttcttt aatcaatcga ttcaatttcg ctaattcttc
    17581 atctgttaag cttacttggc cgttcccttc aattgttaga tgatcggaga tatggaaaaa
    17641 gttccaagca acaacttgac cttgttcatc tttgatccga gcaacattcc atttacgttc
    17701 gacagtgttt tctgttcctt tatcgtcggc tatgataacc atcaaagtgt ctccgacgtg
    17761 tgctttgtta taagcaaaaa tcatgttctt tcctccatta tcctttgctg agatttatct
    17821 taacaaaaaa ttgcattcac tgcatgagat ttttttcatg ctttatttcc gaagaagctt
    17881 cttctggaac accatttatt cgtaacaagg gactgtgaca agacttttgt cacagtccct
    17941 ttactgtttg attaaaaagg ttatacaagt tccacttgct taattactcg gctgttcttc
    18001 ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt atgacgtagc tggctacact
    18061 tcctgtcata aagcgttcga ctgcatttag tccagactgc ccaaccatga ttagatcgat
    18121 tgcatatttt tttggcaatt tgactgccat ggattcacga acagagccgt atgcaataat
    18181 tccttctata tttgtgtaat caacagattt tccatattct ttacattctt cgatcatttg
    18241 cttggctgtt tcagtttgct gatcgactag attttgatca ataggagcat agcccataaa
    18301 attataaaat tgctgatcga ttacgtttgc tacatatact ttcccattat tacggcgagc
    18361 cacttctaac gcttttttga aagcagcaag tgcttgttca ctaccgtcaa tacctactaa
    18421 aatgttctta tattcttgat tcatcttgac ccctcctaac agatgtcagc cttttattac
    18481 actttctagg aacgattcga tttcctgttt tgttttacga tctttattca ctagacgacc
    18541 taattctttt ccgtcttgga tcacgacaaa acttgggata ccaaaaatgt tccattcagc
    18601 ggctacatct atgtacttgt cacggtctac ttcaataaat tgccaatcag aaaagtcatt
    18661 ttcgatttca ggcatttgcg gtttgataaa acggcagtct ccgcaccagc cggcagtaaa
    18721 gaaaaataca ctttttccag tttctacgta gcctgctaat tcttctaaac tatttgggat
    18781 aatcattctt tttcctctac tttctgttta tgtatttttc aattaaatta tacacctttc
    18841 tttcgaacta acaaacattg atcctctttt tataaaaaaa atctgacaaa aggttgcttt
    18901 tgccagattt tatagtttca ctatcgcgtt atttcccgta tacgatcgtg ttcactgttg
    18961 atttatctaa acctttcaat gtttgaatca acatttctcg tgcagcttca aaatcgcgaa
    19021 tactgaacat cgtttgatgc gtatggatat aacgtcccac tacgccaatc actgtacttg
    19081 ggattccttc attttgtgta tgagcagcac ctgcatctgt accgcctttt gaaacaaagt
    19141 attgataagg gatgttgttt gtttcagcga tatctagcaa gtactcacgc aaacgaggaa
    19201 gcatgatcaa acctggatct tggatacgca tcaatgtacc ttctcctaaa tgtccgaatg
    19261 tgccattttt cgtcactgtg tcatctgctg cagagcagtc tactgcaaag aacagatctg
    19321 gcttgaattt attgacagaa gctttagaac cacgcaagcc tacttcttct tggacattcg
    19381 cgcctgcaat caatgtatga cctaatgttt cattttgtaa cgcttctaaa gcttctaata
    19441 ccattgtaca gccatagcgg ttgtcccacg atttgctgat gatattcttc ccgttggctg
    19501 ttttgatcgt ttcagcgtaa ggaacgattg tgtctcctgg aagaacaccg taactcattg
    19561 cctcttctct tgattcaaac ccagcatcga acaaaatatc tgttacttct actgattttt
    19621 gtccgcttgt tcctcgtaat aaatgtgggg gaacggaaga agaaatacat ggataattct
    19681 taccagtaga ggttttaagt gtaaaacgtt gagcagaaac aacgtaaggg ttccatccgc
    19741 ctagaggtac gactttaaaa agcccgtttt cttggatttg tgtcagcatg aatccgactt
    19801 catccatatg tgctgcgacc attacacgag gtgcatccgc ttcttcatgg tggcgcagcc
    19861 caaaaatgcc gcccaaacca tctaactgta actcatctac cagcggttcc atatgacttt
    19921 ccatataggc gcgaacgtct tgttcaaaac cgcttgttcc ttgtaattct gttaactctt
    19981 tgattcgttg aaatgttttt tcttccatat gctattcgtc taaatttcag actaaactcc
    20041 tctcagactt atattgatct gcggataaaa tatgattttt tctgcagacc gatcgtattt
    20101 attatagctt attttttctg gtagcggtta tttatttcaa agaaaatatg agagtgtggt
    20161 aaaataaaca caaagagtag caagtgagaa gaaggaggta tatccacatg tatgaagaaa
    20221 gcgaattaag ctattttaaa ggcgggttag ccgttgggat cggtctagga ttattgagtg
    20281 gggtagcttc aacgatttgg tatcatcgca aaaaagtgtt atcagcagac caagtgcttg
    20341 aaaatatcaa aacatctttt ttaaaagaag gcgcaatcga aggtgcttgg atctcttttg
    20401 aaaaagaacc tattcggaaa ttcgccgttc ggtcgagtgc ttatcggggt gggctttccc
    20461 ggatagaaga tggcgaaact gtttattatg aatttttagc agatgctcat acaggaaccg
    20521 tattagacat ttcaagaaaa aagggcgcaa tagattaata cgtcaaaaaa atgaaataac
    20581 gaatacgcac ccactatcta aaagagaggt atcctatcct tcttttatag tgggtgattt
    20641 ttataaaaat agggctattt cctcttggaa tagctagtat ttgtagttat tatacggtat
    20701 tcttgaaata agattagttt tattatataa ggagagtgac aaatggaatc acgtgaaaaa
    20761 attgccgtgc tcattccttg ttataacgaa gaggcgacaa tttcaactgt tattgaagat
    20821 tttaaaaggg aattaccaga agcagatatt tatgtctatg ataataattc gaccgatcga
    20881 acatacgaat tggccgttca aggcggagca atcgtaaaga aagaaccacg tcaaggaaaa
    20941 gggaatgtaa tccgtcaaat gttttttgat attgatgccg attattattt gatggtagat
    21001 ggtgatgata cttatcctgc agaagctgca catggtttgc ttgagaaatt acgttctggc
    21061 gaagcagata tggtcattgg cgatcgtcta tcaaatggaa cctattttga tgaaaataag
    21121 cgtcctttcc atgattttgg gaataatctg gttaaaaata caattactta cttatataaa
    21181 acaaaaattc gcgatgtcat gaccggctat cgaggattca atcgaatttt tgtcaaaagc
    21241 ttccctatta tgagttctgg ttttcaaatc gaaacagaat tgacgattca tgctttagat
    21301 aaaaaattca agttcgttga gattccaatc gattatcgcg atcgtcctga aggtagcgaa
    21361 tcaaaattga atacattctc tgacggattc aaagtgatca tgatgatcat caaaatgtgc
    21421 aaagattata aacctttgct tttctttggg atctggacca tcttcttctt tttatttgga
    21481 ttggtcatgg ggattcctgt gattcgtgaa tatatgctga caagctttat tacacgcatc
    21541 ccttctgcga ttttaagtac tggattgatg actttagccc ttctttcatt agtaacaggg
    21601 ttgattttgg atacggtcgt cacaaatgcc aagaaagaat atgaattgaa tttataccat
    21661 gtctaccacg aatatcaaaa taaagaaatg aagtaggagg ccttttttat gcataagaaa
    21721 aaggagaatc tatttcctac tttttttgca actttatttg cgtcaggttt tgcttttttt
    21781 acttcttatg gtctaggaac tttgaatcca acagtaatca ttggtttagc catggttttg
    21841 ctacttgctt ttaagcaata tggaatagag ttgttttcaa taaaaaacaa agttgcagct
    21901 attgcccgat tgtttttttc tgcagctttt gctcttacac tttctattgg cagacagata
    21961 caatttcagt atgtctcagc aaactataca aagacaacga ttgctgatgg aagtattttt
    22021 tactttcttg tttatttctc catttttgtg tattcttttt
//
LOCUS       DBGZHO010000046        21614 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.046, whole genome shotgun sequence.
ACCESSION   DBGZHO010000046 DBGZHO010000000
VERSION     DBGZHO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.046"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..504)
                     /locus_tag="ACN3HL_001938"
     CDS             complement(<1..504)
                     /locus_tag="ACN3HL_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006793.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQ"
     gene            complement(728..1612)
                     /locus_tag="ACN3HL_001939"
     CDS             complement(728..1612)
                     /locus_tag="ACN3HL_001939"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HHC8006794.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1711..2148)
                     /locus_tag="ACN3HL_001940"
     CDS             complement(1711..2148)
                     /locus_tag="ACN3HL_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006795.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(2365..3276)
                     /locus_tag="ACN3HL_001941"
     CDS             complement(2365..3276)
                     /locus_tag="ACN3HL_001941"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8006796.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3733..4161)
                     /locus_tag="ACN3HL_001942"
     CDS             complement(3733..4161)
                     /locus_tag="ACN3HL_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006797.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(4189..4827)
                     /locus_tag="ACN3HL_001943"
     CDS             complement(4189..4827)
                     /locus_tag="ACN3HL_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006798.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(4831..6867)
                     /locus_tag="ACN3HL_001944"
     CDS             complement(4831..6867)
                     /locus_tag="ACN3HL_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HHC8006799.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6993..7658
                     /locus_tag="ACN3HL_001945"
     CDS             6993..7658
                     /locus_tag="ACN3HL_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006800.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(9593..12742)
                     /locus_tag="ACN3HL_001946"
     CDS             complement(9593..12742)
                     /locus_tag="ACN3HL_001946"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HHC8006801.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(12755..13954)
                     /locus_tag="ACN3HL_001947"
     CDS             complement(12755..13954)
                     /locus_tag="ACN3HL_001947"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHC8006802.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(13944..15539)
                     /locus_tag="ACN3HL_001948"
     CDS             complement(13944..15539)
                     /locus_tag="ACN3HL_001948"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HHC8006803.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
     gene            complement(16048..16830)
                     /locus_tag="ACN3HL_001949"
                     /pseudo
     CDS             complement(16048..16830)
                     /locus_tag="ACN3HL_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16895..17731)
                     /locus_tag="ACN3HL_001950"
     CDS             complement(16895..17731)
                     /locus_tag="ACN3HL_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHC8006804.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(17749..19158)
                     /locus_tag="ACN3HL_001951"
     CDS             complement(17749..19158)
                     /locus_tag="ACN3HL_001951"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8006805.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(19172..20995)
                     /locus_tag="ACN3HL_001952"
     CDS             complement(19172..20995)
                     /locus_tag="ACN3HL_001952"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HHC8006806.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
BASE COUNT         6550 a         4352 c         3421 g         7291 t
ORIGIN      
        1 ctggaactcg atcgactgag gtatctcatt gatataaata tggtgtgtgc cgaaattgtg
       61 agcgaatcca ccaaaatcaa taacgatatc tcgtttgatc tctaattccc tgtctaaagt
      121 caaaggctga atcagtcgga tcttagttac tgattcgtct gcgagaagct gcgccagttc
      181 ttctgttgtg gcagcttcgc tgtacccatc cgctgaaaca gctcttgcca gtgccgcttc
      241 actgctatca gacgtttgtt cagctacttc tgaggtctca cttgtcttat tttcttcttg
      301 ccttttatta gtagaagcct cactttgaga ttctgtagtt tcagaagtaa tcgattcttc
      361 tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc gttgattcgt ttgttttctc
      421 tacatcggca aaaacggatg tcaccatcaa gagagggaag acaaacaaaa tcgacgcaat
      481 cagctttttt acacattgat tcattctcca ccatcctctc tgacgttttg acaattttat
      541 tttatcgttt taatctattt ccaattgtac tttcatattt aaaatatgta tttttatgga
      601 aaaatttttc tattaggtgt aaatttcttt tttgtacaaa aaaaaggctg tgacaaaagt
      661 cttgtcacag tcccttatcc cgaacaagcg gtgttctccc gccaactcct cggtcacaac
      721 ctccatttta acaataaacc tgtaaatgtg agggcaatac tttgattgtc acaggtaatt
      781 tatccccttc atctccatca acattcgtcg tcaattcttc ctcatcagct aatgacacaa
      841 ctaattgctc acaagtaagg taggctagat ttttcgtaga ttcatctact ccttttaata
      901 ggtctggcaa tgttttaagc gtatcgatca aagaagaatc ttttaaataa accaaatgga
      961 gcttaccatc atccactttt gcatttggaa gtaatgtttc aaaaccgccg actgagttag
     1021 ttagtcctat cagcaaggta ctgctctcaa tttcttcctt ctttccatca acttctacgt
     1081 gaaacgagta ggattgtgtg gaagctaact gtttgattcc tgacatgaaa taagctagtt
     1141 ttccaaattt cgtcttcttc tccgcatcta catcattgat tgattcaggg atagagccaa
     1201 ttgcgacgac attcataaaa tagtcgtcat ttatttttcc aatatccaat ggcttgactg
     1261 attcaatcga aaaatgattg atcgcttcct caggttctag cggtatccct aatgctcgag
     1321 ccaagtcatt caccgtaccc aatgggaaaa atccgaaatt tggccgatgt tcttgttcag
     1381 cgattccact gattccttcg ttgactgttc catctccgcc catgacaaac acactatgat
     1441 acccttccgt agccgcttcg cgagtaaagt tttttgcatc ccctgctttt tttgtatgca
     1501 agacgaccac ttcatcaaac accgattcca attttgctat cgctaattgc tcaaattcct
     1561 ttgcttgttc accgcctgaa ctggggttta ccactaataa aacttttttc atcactttct
     1621 ttcccttctg actgattgat ttctttaata taacgatagc ataaagaaaa aaattaggct
     1681 gtgatgaagt actgttcatg aaacattcat ttattttttg acaagataaa acatccatac
     1741 tatgaaactg aggaaaatta aaacaatgat ataggaaata aaagaaaatg ataggcattg
     1801 tatacctaat aaagtaaaaa tcttaggtgg cagataaaaa cacaaaaata gcaagagaat
     1861 gtaatagcgt ttcttccact ttttgttatc agaccttata gcgatcagag gaataccaaa
     1921 tgcataactg aaaaactctt gatgtactgt taatatgtca cggccttgaa taataaatgc
     1981 gacaatcccc gctataatta gtgtgcctaa caccaaaacg gaaaattgat gaatatattt
     2041 tatatacaaa tgatccattg tacttcctgc ctttttattt gtgagaaaaa caaatccgta
     2101 tacgtgaata acttctagaa ataaaagaaa tttgcaaaac cactccattt atctacttct
     2161 acgtgcattt tttgatattg ttttctttat ttaagattat acagaaaaat atctagggtc
     2221 gctggattct aagtaaaaaa aatttttaaa ataaaaagaa ctaaatcaag tagtaattaa
     2281 actactgttg atttagttct aataaaaaga tttagatgaa cagttttatt gatttaaata
     2341 gttcatattt tttatttata ccgcttattt actacttgct gtactagaat ctgaagtgaa
     2401 tgtactcaaa acattttcaa agtctttgtc tttgattttt acattagcgt ctttcaatac
     2461 ttcgccaatt actttattct ggaaggtact gtcacttaat tttgtgtctg ttgcaatttc
     2521 tttcaattct tttttgtatt tatccatgtc gttgcctttg ttttggtttt tcaccatttt
     2581 aaccacataa tattccgtag tataagttga agcattggta gaagtgatca catcagaaac
     2641 ttgaccatct ttcaacttaa aggctgcttc tttgacttct gccggaaccg ttgtagtagt
     2701 ggaatcaaat ttcacttttc cgccatcttc ttttgtcgta gtatcagttg acttgtcttt
     2761 ggctaattta gagaaatcgt ctcccttatc agcagctttc ttcacatctt ttgcatcatc
     2821 ttcacttgct acttggataa tttgagcttc cacttctgga tggaaagatt cccaagccgt
     2881 ttttaaatct tcatcggtca atttgatatg tttctttaga ccttcttgaa aggctagact
     2941 ttgtttgata ctgtctttga atgtttgttc tgtgtaacct gcagatttca attgtgaatc
     3001 aaatgaatca cccaattgtt tctttgtttg atcatattga gaatcgattt ctttggttga
     3061 tacgtcatct ccatatttat cttcaaatac ttgataaacg atcaactgtt gcacagcgga
     3121 atctgctcct tgcatttttt tcaagctatc cattacttct tgttcgctga ttgtaccgcc
     3181 tttataacta acggctgttt tttcaccggc attcgtacag cctgacaata agccagtgcc
     3241 tagtacgatg gcaagtgcta aaaatctttt tttcatttat caattctcct acttttcgtt
     3301 ttttgcgaat tgctaaaaac aaaggtgttc aagatgaaaa tcatcaagaa cacctttact
     3361 aatctgctcg atacgtcctg aatagatata aggctacaca atccagaaag ttcgctcagc
     3421 agaataaatg tcaagtagca catcacacct taatatacta cttcttttgt taccgttttt
     3481 caagtctatc ttgcgttccg tatttaacgt aactaattct tagaacaaat gttatcgatt
     3541 ttgtttttct tcttccgctg ctgggatatt caaatcagac acttttatgt tcgattttcc
     3601 agacattttt ttgttgtttt tattatgata tatttttata caactaaaaa tgaatatatt
     3661 aaaactacca aaaataactt ttaacgctgt ttcattatat gttttttcta ttttatataa
     3721 acttttggat acttaatacc aaccggttgg attgtaccaa catgagaatg tgtcagttct
     3781 atttcctgtc gcacttgcat aggcccatac tccttttgtt gcatttgctg atcgaataga
     3841 gtttccaact ttcgcttttg caccgtgacg attatagaca cgactatagt ggttagaatg
     3901 acctgttttt ctcgtacaag ttgtatcact ataataaacc catcttccag agctatgatt
     3961 aattgctgtt ctagaaattt cccggtctac tggtaaattt gacttaataa tattaccttt
     4021 agcatcaaaa tgaatctctc ctggctttaa agatttgtaa tagatttcac cgtgaactga
     4081 atttgcttcc acttcagatg acatagcgtt tcctccaaca aaacctatcc ctagtgcaca
     4141 aataataact gcttttttca taaaacgaca tcctttcctt tttgattttt aaagcatgat
     4201 cttcttgttt cctattttgg tcagatatgg atcatgcgtg actacgataa ctaacgtacc
     4261 ttgggaagct tgttgcgata agatttcaac tactttatcc ttatttcttt tatccaatga
     4321 cccagtcggt tcatcggcta aaatgatttt gctattcttc aataagactc tcgcacaggc
     4381 gattctttgc ttctcaccac cagataatgt gtagataggc gtacttagct tcttgtttat
     4441 atttactttt ttcaatgcct catactttgc tgttcgctta tctgaaacat ttaaattcga
     4501 aaacttcaat ccaatatcta aattaaaatc gattgtttca tattcaatca acccaaaatc
     4561 ttgaaaaaga aaagatatgg tatttctttt tatcaagcgc ttctctctcc cagttaattg
     4621 tttcgtctct tgatcgaaca aatagaattg tcctgaactg aactgatcat tcaatcctaa
     4681 tatattcaat aacgtacttt tacctgctcc actttctcca acaacagtca caagatcccc
     4741 agcatccgca gtgaaacgat ccaaatgaag aatcgttttg tttcgaatga tttttttcgc
     4801 accttttatc actatcaacg gctccaattg ttaacctcca ttcatcagca ataactgact
     4861 tttcttttct gtagacaaaa taaaaacaac tgaaagaata aaatcaatga agctaaagaa
     4921 aaaaatatta aaaagatatt taggctctct ttctataaga aaaaggaaga ttacacttgt
     4981 cgttccccat ttgatgaggt tcatcatgaa gaaatcttta tacgtttcaa agagcgaata
     5041 accacttgaa cgaaagatag cgattttccg acaattgtag acaaaatata tgcataacat
     5101 gacatagctc aacaagaaga aagaaaagaa agtgagtaaa aatatctgta tcaagtaatg
     5161 aaatgatctg cttaacactt tgacagctat ctcttcagtc tgagtatacg gaaatgataa
     5221 ctgcaagtta tcacgtaact gactttcttc aatcagctca aataaccttt ctttcgacaa
     5281 agagcctatc ttgatcttta acggtggata gatttctccg ctgagaatat ttctttccaa
     5341 atacatactg tttttcaatg tcagtatttc aacaaccgga taatgttcga tccaggggat
     5401 agaaggaata aatgtataaa tgggttgatt gttttttata aatagaaatt tcggttcttt
     5461 ttcactgatt tcttgataat attctgttat ttgcgccagg tcatttttta aatctgtatg
     5521 tctatatcgt tcagggatca atataacagg gtgcgtttct ttttcggtta tttggatcaa
     5581 ccttccagag acatcaatca aaggaaattt cttaagataa ttcagattta tttttatccc
     5641 tctgccaaac tgttcatttt cttcattcaa gtaatctgat acattgacta atatacttcc
     5701 gtttttattc aaagtttcat ataattcctg atctgctgct gatgcaaaac gattggaata
     5761 aataaaatcc acgtggtttt tcccgatggt tactggataa aatacatgat agtcctcacc
     5821 agcgatttct tttggtggtt catgggaaac agctaactgt gaagaagaaa aaacgatagt
     5881 tgctaattcg acattggcaa cggtcaaaag aagagaaaac aacaatccaa atgtaaaaag
     5941 aatgtattgg atatagttga acgcttctct taacgaagcg attttttcaa ctaataaaag
     6001 agaaatcaaa gagataccat atattccgct gaacaagaaa acgtacatct ggaacaaata
     6061 aagaaattgc tccttataat acataaaaat aaaaccacca atgattcctg caattatgaa
     6121 tgtaataatg attttctttt tccccaataa acaccacaat acttgatgta atgaaaagtc
     6181 attattcaac aataaactga tttctttatt catcaataag aaaaaggatg ataacaaaag
     6241 gaataaaaga atcaatccaa tagttaaata cactcgataa ttatatacgt ctgtatttga
     6301 aataaccgaa tacgaatagc tattttcaaa gtcttcaaaa atattagtgg cataatcagt
     6361 gtgaaatgct tgattgaatc gatcagtgaa tagtgaaatg acccgttcat aggcttcttt
     6421 ttctctcgtc atcaagaaaa attcaccttc aaaatctttt attttgatcg attcttcaat
     6481 ggacgttacg cgaaaggagg tattagaata gggtaccttc tcgtgagaag atttgacatc
     6541 cccttgataa tacaatgtca tttcaagctt tggctgtatc ttgaagttcc aagatgtatc
     6601 tacttcattg gattcattta ctgttttttt catataagaa agctcagttt ctgatgagac
     6661 attttcaaat accatgatta gctgctcata ttcttcttgc ccaataaaat gttgtggcaa
     6721 tcgaatcgga gtataagtat ctgtttgatg gaaaaattca tttgtccgat agagtacctg
     6781 tttatttata ctaaccaagg caaaaccact catgataccg gtcactatga ttgtgagtaa
     6841 aactgtgaac ttttttttga ttatcaccac tctcccttac ttaaatgatt ctttgataaa
     6901 atcataccgt ttttcatcaa aaaaacgtat ctatcaagtg tataggtcat gtagaataaa
     6961 tctatatact gtagaatcga aaggagaaga agatgaacac cggagaaaaa atacgaactt
     7021 accgcagaaa ttgtaagctt acgcaaaaag aattaggcga aaaaattggt gtttccgata
     7081 aaacgatttc tagttgggaa aattctcgta caatgccaga ctttgaaatg ctgtcacttt
     7141 tacatcatac tttaggtctg ccgattgatt ttccttctat tgaatcagct accgaatcaa
     7201 tagaaccaac attgccagat gaacctcttg ttaacaagaa atcttattca tcaaaacaac
     7261 ccttctcact caaaaagaca ctatctttct ttctgctcgt cttttgtttg gtctatcttt
     7321 ttcttatcaa ttatcaatac aaaaatgaaa cgatcgatcg attcaatcct tttttgaaac
     7381 cacaaatcgg ctataccaca ctccctgtag gatacgtgga caattccatc gaacgttggg
     7441 tatgtaatga tatctttggc catggtacat ggctgtcttt tcacgctgga gaggtagaaa
     7501 aagagaaaaa ccatgctgta atcaaacaca aaggaaaaca cgtcatgaac gttcgcctgc
     7561 tcacttggga agccattccc tcagattacc aagaaatcct cagccaagac tatgacgacg
     7621 ccttaaaaag aagccctcag gagccagata ggcattaagt aggagatgaa cgtagagata
     7681 gaaaaaatca atgcacatga tcttatccaa aaaacagggg tacaaattaa ttgaaaaagc
     7741 cttgagatga aagttcctaa ataaaaaagt tcagaatgat aggtatttct ggcttatagt
     7801 ataatattta cgccacagcc tcccaatgat tctttttgga atcataatca aggatggaca
     7861 ttcacaaaaa tattttgctc attcgatccg aatagattaa cgaccaatct agtaagtaat
     7921 atagattggt acgtagtcaa gctgcacata atttagatca attttagttc ttttttatat
     7981 ttctatgatc tgctcattta cttttatatg atggcttaca gtaacataaa taaatatgat
     8041 aatcgctggt agtttatcca agagtactca ataaaataca aaatggattg ttcaagcgcc
     8101 tatcataatg ataaaatgaa acaaataaac gatacaagga ggaagagact ttgagtaatg
     8161 gcagaacaat tttttcattg taaaaattgt tcagttgtta atctatggga tttcggtagc
     8221 atgggcattt ttttatagag gaatcacacc aacctggccg ttttatctct tgttagtggg
     8281 aatattagta ggaaattttg cccctcttca ctatcgtacg aacttttttc caactgattc
     8341 tggccttttt cttaaaacaa agacgcgaaa attagaaaac attattgaaa tgacaattac
     8401 ctgtataatc attttcttag ttatattcct aaacgtcttc taataagaat ctcttaaaat
     8461 tagcttgtta cagttagtta cctagtttat ataacacagt tatcttatct tccttatcaa
     8521 catcttttgc caactctttg tcttaaattc gaaacatata agcagagcta cgaacaccaa
     8581 gactgtttcg gctctgtttt ttgcatcaaa ttcactctta tatagctgat aatctcggct
     8641 ctttaaaaga aattattttc gcttcatttt attataaaaa ggctaggaac cttgatgtta
     8701 tcaggttcct agcctttatt taagtattac cccacagacc cttccatata gatttttaaa
     8761 ttacacacta gtttaaacta aaacaaacaa ggaaaaactt accatttaat caaaaaatta
     8821 gctcatatga atatattaga atgtaaatta gactggtcaa aatctggtca aaaaagagga
     8881 cgaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt ttattggatt
     8941 attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac tgagtcatat
     9001 agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt taaaatcaat
     9061 acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat atacagtccc
     9121 ataggtaaag tgccacagga ctgtatattt ttttatttga gattacctga aatgattcca
     9181 tttaattttt atctcatttt ttcctactag ttagtatcaa atactctcct attttctcaa
     9241 taaactattt tgggttacat ggtatctgaa acagctaaaa ccttgtcatt atagcaaaaa
     9301 atcactttat ctccgtttca tttcagatac atttcactta agcggattcc aaaaaaacaa
     9361 aagaaaaagg aacccctagt tagcctatgc tttttattgg ttcctctcaa aacacggtca
     9421 tataacaacg gggtggggta aatgaatgaa aaaggtggag gaaacattat tcaatagctg
     9481 tcttaaatac ttcgttataa aatgtgaaca aataaaagac atctatccct attttctaca
     9541 cttccacttg actaccatct ttgaatcgta caattttctt aactcttctc gtttacctca
     9601 attcattctc aagtggaatc aactcatcat ctaacatttt acgccatgct cgcttcattt
     9661 cttgtgggta tttaaatggc ttcgcttctg gatgtttggc tttatatcct tcgtaatcct
     9721 tactgttgat aattgctttc atattaggaa ttggatcttc acctggtaga tattgcagat
     9781 tagaagcatg taattctttc tcagaaacaa accactcatt ggaaaagaca tgaatcaaat
     9841 catcactcgc ttgtgtaaaa tagcgacgtt taatgacaaa gatatcttca ttactatcta
     9901 aagtccccac atcaaatgca tttaaaattt gtcggtaaac ttctttgact ccttctgttt
     9961 tattcaattt agccaaagct ttttcaattt cttctcgtgc atctgaacta ttcgcagcat
    10021 aagttcctag taattgatca atataagttg aatcaatatc atacaactta gtggtatttt
    10081 cactataaaa ttcgatcgtt gaaaaatctt ctccttcttt ttctggttct tcctctatta
    10141 atgaaccctt cacggtctcg tacacgccaa tttgttcttc caaaagttga atttgattgt
    10201 tcaaagttgg agatttcacc atgtcatcat tgtaatcgtc ataagtcact aacgattcat
    10261 aagcacgatt caattcttga aatgctttga cgtactcgat acggatttca agtggcgtat
    10321 gttcatcaat ggattccatg gatgaaacct cttttaactt accatatgct tgtttgaatc
    10381 tttttttgga ttcctgataa cttggataaa tcaaacctga ttcttctttt gcttttgaat
    10441 acagttttgt cgcatcctcg acattcttct ccattgtcgc tggcttacga aacgtcacaa
    10501 tcaatccttt tgtcttatca ggatacgtac gattcgtacg tgaaaaagct tggatcaatc
    10561 ctgcatactc tagattacga tccacaaata gggtttgaat cgtaggggcg tcaaaacctg
    10621 ttaatagacg atccactaca atcgctaaat cgatttgttt cccaaattgt ttgaattccg
    10681 ctctttttcg tgccaaacga ttattgatgt ctccgttata acgctcaatg tctgctaatg
    10741 accaggaagt atcataatac tgattatatt cctcaataat tttttgcatt tcttcttgtt
    10801 gggcacttga atctcggcta ttttcttcta atgaataggt aatagcgatt cgtggaaaat
    10861 caggatcctc catcgttcgt ccttcacgaa tgagctgatt gggaaactct tttgttaacc
    10921 aatcaggctc tttcgtcatc tctttgatgg cccgataata ctttttggcc atgtcaatgg
    10981 aactcgtggt taagattgca gatttcgttg gcctgccatt tcgaaaatca aattttgtat
    11041 aggcattatc tggacggaac attttatgaa tgactttttg gatatgttca tctgcttcaa
    11101 aaacagctgg gtccaaataa ctttcttttt tgacaggttc catttgatca atcatacgat
    11161 tgatctgttc tgatgaatac tctgcatatg tttctacttc ttttaatttc cgatagattt
    11221 tattctctag tgaagtcggc tccacggtgt tttcatgctc tacttgaaat cctaagacag
    11281 agccatcttc tagcgcattc ttaatggtat aggtatgcaa gacctctcca tactgatcat
    11341 gggttgtacg tgccaattgc cctttggctt gtttccgatt ctcaggaaaa atcggtgtac
    11401 ctgtaaagcc aaaccaagtg gatttcggaa acattttttt gatttcttcc atattttcag
    11461 cacttaacgc tcgatgacac tcatctacta caaacacgat atgttggccc attaattttt
    11521 ggaagcgatt ggttcctttt ttctcttctt gtttctttgc atatttcaac gccgcatcta
    11581 gtttttgacg ggttgtaatg attacaacat ttgcattggc atctgccaac agggtttcac
    11641 ttaattcttt ggcacttccc gttccaacga tcaagctatt cgctttggcg ttcccggaag
    11701 aaatcccagt attaaattcc gaagcaaatt ttgtaaactc tgtggtggtt tgattatcta
    11761 aatctttgcg gtccactaac atgatcgttc gatcgatccc cgattttcgt gctaaaagct
    11821 tagtagatac aaaactagtc aacgtctttc ctgaaccagt cgcatgccac acataccctg
    11881 attgatgttt atttgcggca ataaacaagg cttgaatcgc atgtacttga taaggatgta
    11941 acaccatgag ggttttatta tcttgatctt cactgacgat tgtataatcc gcaatcaaac
    12001 gatgagcatc cgggatattt aacacttgtt tacaaaactc atataagttt tctacttttt
    12061 cattgtcttt cgttcgccaa ctaaataaaa acttagggtg caagtctttc ggtaaggcat
    12121 ttgcaaaata ccgagtggtt tgttcattgg aaaccacaaa caactgtaag gtcgaaaaga
    12181 tattgttccg aaacatacct tcttctgcat attttttgat ttggttaaat gcctgataaa
    12241 caccatcttt tgcagttact tgtttcagct cgatttggac aatcggtaat ccattgatta
    12301 ataaggtgac gtcaaaacgt cgatcccgtg cttctatgtt acttccacgt tttgcaattt
    12361 gatggaccac ttcataagta gagattcctc caccaatgtc ttgattggaa taaaggataa
    12421 gtgagacaga acccaattgc gaatcttccc gttcaatcgt gatccgagcc atcccatttt
    12481 caccttttaa ccatttcgca gcatcaaatg gggttttcgt tcgcagcagt aattccgttt
    12541 tgatcgtttc aaattcttta tcggtcaaag gaaaatcatt cagttctgct tgattatttg
    12601 agataatttt ttggcgtaaa ttgacccaaa ggtcttcttc tgattttaga tccggacgat
    12661 acgtccactg attatgccct tctccaagta cacgaatcaa ctgttcttcg acttctgctt
    12721 cctcacggtg actaattttc attcttcttc cctcctagac aaacatcttt tgtaagaagc
    12781 tttttttcgt ttcttttagt aaatctaact tacgttgatg aagagcgatc gtatcatcta
    12841 gctgtttgaa gaaagtaccg attttttgtt gttcatcctt tacaggaacc ttaacactga
    12901 tattctcaat atcagaactg ttataagaag gcaatgcccc tacttgggag tatcttggca
    12961 aatttatagt ttcaaacaat attttaccaa aatagatatc ccaagtatta ttaaataaat
    13021 aagccatggt attgttatct attaagaaag ggcttgtgac caaacgtttt ctattaagca
    13081 ttattgctgc gccaacttta gcaaatataa tcgctggcac atcttttatt ggcttccatt
    13141 ttttacgctc aatttgctca ttagatacat aatgatttgc atttctcatt tcatactcat
    13201 taccaatgtt attcatgtcg gaaactttaa aaaatggagt accttcagaa ccaccttgct
    13261 cggcatcagg aaatccaatt cccgattgag ttttacctaa ttctcccaac ttacgctctt
    13321 cccaatcttc cgtaaaacca ggaaaccgga tttctggcac ttttgctccg ttttcaggga
    13381 acattttttg taagaatcct tttttcgttt ccttcagcaa atctaactta cgttgatgaa
    13441 gagcgatagt gtcgtcgagt tttttgaaga atatgccgat tttttgttgt tcttttaaat
    13501 cattgggaat atagaatact gtatctgaaa cttttttcca gtctgaacga ggcatttttg
    13561 ttccagatgt atcatttgca gccttttgat atctatcagc ttgaataaga gaataaataa
    13621 agtccgagtc gctcttctta gctctaaaaa cccagaaatc cccaatcgct acgcctgtaa
    13681 aagttgcctt gagccaattt tttaaatatg gacgtaactt tccatataga atatcatttg
    13741 gtaaaaattc aatccctttt ctattatcaa atttctggct cacatcttta ttcagtctac
    13801 cttctcctgc cacgatatct tcaaattcaa cttttggaag tctactggag tttgtacttt
    13861 tattaagtct aacaactaaa tcaattaact tacgctcttc ccaatcttcc gtaaatcctg
    13921 ggaaacggat ttctggtcgt gtatcattgc tcatgtttga acacctccag cgcaccttgt
    13981 aaccacattt cgttttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt
    14041 tctagcactt gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca
    14101 attggttctt cttcttcgaa agtatctaca tagcgtggga tatttaagtt atagtcattt
    14161 tctttgattt catcaaaggt tgccaaatga gcgtatttct cgacatcttt tctttcagcg
    14221 taggtttcga ggattttttg aatgttttct tccgatagtt tattttgatt tttcccttta
    14281 acaaattcac gactagcatc aatgaataat acatctcgag tttgacgatt cttcttcaac
    14341 acaatcaccg tcgttggaat cgatgtccca aagaacaagt tcgcaggcat accgatcaca
    14401 gcataaatac tgccatcttc tagtaatttt tgacggatga ccccttctgc agcgccacgg
    14461 aataaaactc cgtgtggtaa gacgatggcc atggtacctg tttccttcaa atgatagaac
    14521 ccatgaagaa gaaacgcaaa atctgctttg gattttggcg ctaatttccc ataacgatta
    14581 aaccgagaat catctaagaa agtcgtatct gctgaccaat tagccgaata aggtgggttc
    14641 attactactg catcaaatgt gtaaggttca tctgttggcc agtccttatt caacgtatcc
    14701 ccattgcgga gattcatttc ttcggcgtcg acaccatgta aaatcaagtt catttttgct
    14761 agattgtatg tcgttgtatt tagttcttgc ccatgatatt taacgttatc tgggtgtgtt
    14821 aagtagttac gtacgtttaa catcaatgaa cctgaaccca tcgttggatc aaaaacacta
    14881 aagaatcgtc gttccttttg atcgagcgtt acgatttgcg ccatcatatc agaaaccata
    14941 tgaggtgtgt aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga
    15001 aactcatacg catccccgat cacgtcccca tcgtgttcta aaacatctac atcattcaat
    15061 ttcttgatga cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt
    15121 gattggagat ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc
    15181 acaaaggctt tgtttagatc gttcaattgg aacgttgctt gttttgcttg atccgctaag
    15241 acgttgaaaa gatactctgg tgcaattgca tatcccaaaa tatcaacgat tgtggcaatc
    15301 agatcttctt ttgattcttc atctgaaagt aattcacgat acaacattgt ttgtttgctt
    15361 actgtgtcat attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaatcga
    15421 tcggataaat atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc
    15481 attttactac ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa
    15541 aagatacact cctatctctt atttaaagtt gctatatacc ctcttatttt agcatacccc
    15601 cttttataaa aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa
    15661 ggagtctaac gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta
    15721 catagttatc tttagaacca tttcagatac atatgaaaca attacatatg attttttcat
    15781 aaaaaaacag tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta
    15841 aaatcactac ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc
    15901 gtttcatttc agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca
    15961 gtagcttatc ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt
    16021 aaataaatga aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta
    16081 atcagttacc tgtccgttct taaataccac agaataatct ttttacccat tttcaagtaa
    16141 ccgaagtgga atgtctttac caacttgctc tgtcactgca ttactgatac ctgttagatt
    16201 agctaataaa tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt
    16261 gattccttta tcttcattta caagcttcca agtaggtggt atagctgtgt atgtttcgat
    16321 gaatgaatca attctttcat ctatcgtctt cccagtatct acttctgtct cattactctt
    16381 agatgaatcg attctttcat ccatcgtctg ctccgtaact gcttctgtct cattattctc
    16441 accggaaact ctcttcacac ccaaacttat atattgtcca tctttagtgt gcatagttaa
    16501 aattcccacg cttttactaa taaattcact ataaccagtt ctttcaatag agacttcaat
    16561 gtatttcaca ctatcatact caaaagaaaa atagacatgt aaaagcattt tgttgtttac
    16621 atctacataa taatcctttg actctacttg agaccttcct atacggaata cagctttact
    16681 gtctgatatc tctataccag catccttatt attaatctgc caatctccaa gtagctcttc
    16741 tggcaagcta gtagtttctt gtgaacactt taccacttca ctggtagagg tcgaaacatt
    16801 cacctccgca ctgttagaag aattttccaa ggaatcagga gccttagcac aaccaacaag
    16861 tctttatata ttgtgcagcc gatattttct tcattcagta cacccttgaa atatgcagtg
    16921 ttagataaag cagttcgtcc tgatttgctg aggcacccat ctcttcttga acgtactcct
    16981 tgattttcaa ggccgcccga tactctttcg gaaaacgctg cttcactgaa gccagcaaaa
    17041 aatcatcctt ctccggcaac tcttccttct taatcattcg ggcaataaaa aactgtaaat
    17101 gcgtcacaaa tcttaagtaa agcatcgaat ctttatcaac ctttttttcg ggaaacagat
    17161 atcctagcat agccaagata tcctttagtg ctcttaccga gagcatggtt tcttccatat
    17221 ttgcttgttc actttgggca tttacaatgt gaaacgcaat gtttccagcc tcctcttctg
    17281 gcaactgaac attcattttt ttgttgatca attggatagc atagcagccg atctcaaatt
    17341 cttttgggta atacttttga atttcaatca gcaggcgatt ttgaaaaaca atgccttttt
    17401 gactgcgttc aatggcatgc ttcaagtgat caaccaaggt aaaaaataga cttttattca
    17461 gcttaaagtc aaacttggcg ttggcataat cgataattcg cttgacgcaa ataattagat
    17521 catccggagc agcctcaaac agtttaatgt aatccttttt tagagcatca gaaagtgaat
    17581 ctaatttaaa tactttttgg attttgtcag ccggaaccaa atcgcctttc tttagttgaa
    17641 atccaatccc tttccccatc aaaattactt ctttgccttg cttatctaag caaagaatta
    17701 aactgttgtt taacgtttta attactctca ttagattcac cgttctctct aagctaagcc
    17761 atttcttgcg attacttttt gataccaaaa gaagctttct ttttttattc gttttaattc
    17821 tttaagattc tcatcggttc ggtcaacata tataaaacca taacgcttat tgaagccttg
    17881 atgggtacta acaacatcaa tcgctgacca aggtaaataa ccaaaaacat ctacaccatc
    17941 tgttaaagct gcttgaatag ccagaatatg tttggctaga taatcaattc gatcctggtc
    18001 attaattcgt ctatcttcct caactatgtc gggtgcccca tagccatttt cagtaattaa
    18061 aataggtaaa tcatagcgat cgtacaattt cctcaatgtt aatcgtagtc cagtagggtc
    18121 aactacccag ccatatggcg ttttatctac ataaggattt tcagctgccc ggtagacacc
    18181 ttcttctccc aacatgatct gttgatcccc cgctctagcg gaaacatctg atccgtcatt
    18241 tttgctggca gcgatggtgg cagttgaata ataattaatc gcaataaaat cgggtttacc
    18301 ggaggataaa attgcctgat cctctgcctc aattttagga tataatccac gatcattcaa
    18361 atagttttca aacaaataat tgtattttcc ccgaactgct acatctaaga aagaccagcc
    18421 tctcaatgtt tcccaattat gggctgcaat tgcatcttct ggactggagg tagcttgata
    18481 catagccgtt aaattgattg ctggaccgat ttttccttta agattcaact gatgatacaa
    18541 gtgaattact ctagcttgag ctaataaaac atggtgatta atttgaaaga gttctttttt
    18601 tgaaggcagc tctccacttg gtggcaaacc aatcgctcca ggatgaagga tcatcgtgtt
    18661 ttgctcatta attgtcagcc aatagttcac cttgtcacca tactcagtaa gcaatacctg
    18721 tacatagtcc acaaaataat cgatagttgc tcgatttaac caaccgccct gctcctctag
    18781 aaaataaggt aaatcgaaat ggtacatggt gacaatcggt tcgattccct gattcaggca
    18841 ttcatcaatt acttgatgat aaaaagaaat tcccttttga ttggttttat tattttcaat
    18901 atccataatt cgcgtccaag cgatggaaaa gcgaaaagct tttaagccta attctttaaa
    18961 cagctgtata tcttctttat agtgatggta aaaatccgag gcaacttcaa aattagctac
    19021 cccttctgta tgctgatact tgtcaataat agacggttgt ttcccatcct cctgataggc
    19081 accctctgcc tggtaggcac taatggaggc accccataaa aacttctctg gaaatgctga
    19141 aagctgtttg tattgcacaa aaatcctctc cttaactaat ttgcatcaat ggttcgtgtt
    19201 cctttaagct tccgcttgct tcactaattc ctgcgtaatt ttcactgttg gtcactacca
    19261 caatcactgt atcatcgtag ccagcgtttc taatggcagc gaaatcggcg ttgattaata
    19321 attgtcctgc tgacacctga tctcctgctt ttacaaatac ttcaaagggt tcccctttta
    19381 aattcacggt gtcgatcccc acatggatca ataattcaat accttcttta gaacgtagac
    19441 caatcgcatg tttagattct aaaatagtaa tgacttctcc ctcaacaggt gaataaatgc
    19501 tgttttcttc tggatgaatg gctacgccct ttcccaatag tcccttagaa aagacagcat
    19561 cgttcacttc agaaatagga cacacggttc cttttaccgg attttcaaca atgactgctt
    19621 cggctattgc cgtttgctct gattcatcag aagtatcgtc aaatccaatt agataagcaa
    19681 tgataaaggt tgcaacaaag gcgattacac acgtaataat tgcgtgaaca atattcattg
    19741 gattttctcc aataaaggct ggtaaggctg ctaagccagg ggaaacaaag gcatatctga
    19801 ctaaaccgct caagccagca tacaaaccag caattgcacc accaatcatg gaagcaacta
    19861 atggtttttt cagcttcaag gttactccat agagtgaagg ctcagtaatt cccattaaag
    19921 cagtgatccc agtggacaca gctagctgct tcaactcttt gtttttagtt ttcgcggcta
    19981 cagcaaaggt agcacctgat tgagcaatat tagaagccag cattcctggc ccattgatca
    20041 tttcagaacc cgtactgctc aattgcatag tagcgattgg cgtcattgcc caagctgtac
    20101 ccgtaaccac caaaaatggc tgcaaaccac ccatcaaaaa tggaattaac caagctgctt
    20161 tgccgttaat ccattcagcc cccattgcta taagatcgtt cagcaacgtt ccaaacggtc
    20221 caatgacaac caacgctaaa ggccccataa ttaaaaatac cagcatcggc ttagtaaaga
    20281 atttaataaa cgaaggcgaa attcgatccg caaagggctc tacataggac atgatccaaa
    20341 cagtaaagat aatcggtaaa actgatcccg cataatctgc agctaatacc ggaattccta
    20401 gaaaagaaac ggcatcgcca gtagaaaaaa gctgtgaaat atttggatga agcaaaatgc
    20461 cagcaacagt aatcgccaaa attgggttga catcaaactt tatggctgcc ccataggcta
    20521 atagtactgg cataaaataa aaggctgcat cagcaatagt attcaaaatg atgtaagttt
    20581 gactactgtc tgatagtaca ccagtcaaag tcaagacggc caaaatggct tttaccatcc
    20641 cggcacctgt tatagctgga atcatcggtg taaaggtggt agaaatgaca ctaatcaatc
    20701 ttgaaataat actttcttga ttgtctgaag aggggccctt tttaattgaa gttcccactt
    20761 ccttttgaat ttccttgaag gctgtttgga cttcattgcc aatcaccact tggtattgtc
    20821 caccgctatc caccacacta attacaccaa gtgttttttc taaggctttc gtatcggctt
    20881 tccttttatc tttgagttca aaacgcagtc tggtggcaca atgggttaag ctgaccacat
    20941 tttcttttcc cccaacctgt tgcaatacat ttcttcctac ttctctgtaa tccattattc
    21001 tctctcctta aagcagtaaa aaagaccaag tcaaaccacg ccccaatcaa cattgaagtg
    21061 ttagtttgtc ttggtcttgc ctgcataatc agtaacatgc caataacgtt attttgctgt
    21121 aatccaataa tagcacatta tgatagcgca atcaacaggg aatttaattt tttatctttt
    21181 cgtttgaccg tatagggtaa tataacagtt agatcacatc aactagggta tatctgcgta
    21241 tacttactgc taaaataagt atatctaata ttaactatac cagtaaaacc attcctacat
    21301 aaccagcggg aaattcccaa aatcgtgaaa gcatcaaaaa tgcatataac ggatcacaca
    21361 acttcaacaa ttctgctctt gggaaaaatt gatgaatttg gtgagtaaag gatggaataa
    21421 acagcattcc aacaatatag gcaacaatag tgatacttgt ttttttggta aaaatcagta
    21481 agcaatagcc aatttcaatc attccgagat ataaaggtat caatagaatg atttgggcta
    21541 gtattcttaa aaattaacta gcaaatgttt aaactgattt atttctaatc tacatgtagt
    21601 aagtatttca attc
//
LOCUS       DBGZHO010000047        21592 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.047, whole genome shotgun sequence.
ACCESSION   DBGZHO010000047 DBGZHO010000000
VERSION     DBGZHO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.047"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            103..1527
                     /locus_tag="ACN3HL_001953"
     CDS             103..1527
                     /locus_tag="ACN3HL_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HHC8006807.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(1569..1826)
                     /locus_tag="ACN3HL_001954"
     CDS             complement(1569..1826)
                     /locus_tag="ACN3HL_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006808.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            1988..3097
                     /gene="pdhA"
                     /locus_tag="ACN3HL_001955"
     CDS             1988..3097
                     /gene="pdhA"
                     /locus_tag="ACN3HL_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HHC8006809.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            3100..4077
                     /locus_tag="ACN3HL_001956"
     CDS             3100..4077
                     /locus_tag="ACN3HL_001956"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HHC8006810.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            4102..5745
                     /locus_tag="ACN3HL_001957"
     CDS             4102..5745
                     /locus_tag="ACN3HL_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HHC8006811.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            5753..7159
                     /gene="lpdA"
                     /locus_tag="ACN3HL_001958"
     CDS             5753..7159
                     /gene="lpdA"
                     /locus_tag="ACN3HL_001958"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HHC8006812.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            7321..7596
                     /locus_tag="ACN3HL_001959"
     CDS             7321..7596
                     /locus_tag="ACN3HL_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HHC8006813.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            7602..8369
                     /locus_tag="ACN3HL_001960"
     CDS             7602..8369
                     /locus_tag="ACN3HL_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HHC8006814.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            8537..10366
                     /gene="typA"
                     /locus_tag="ACN3HL_001961"
     CDS             8537..10366
                     /gene="typA"
                     /locus_tag="ACN3HL_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HHC8006815.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            10627..12399
                     /gene="recQ"
                     /locus_tag="ACN3HL_001962"
     CDS             10627..12399
                     /gene="recQ"
                     /locus_tag="ACN3HL_001962"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HHC8006816.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            12513..12815
                     /locus_tag="ACN3HL_001963"
     CDS             12513..12815
                     /locus_tag="ACN3HL_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HHC8006817.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            12818..13981
                     /locus_tag="ACN3HL_001964"
     CDS             12818..13981
                     /locus_tag="ACN3HL_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HHC8006818.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            14007..17435
                     /locus_tag="ACN3HL_001965"
     CDS             14007..17435
                     /locus_tag="ACN3HL_001965"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HHC8006819.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            17456..18580
                     /locus_tag="ACN3HL_001966"
     CDS             17456..18580
                     /locus_tag="ACN3HL_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HHC8006820.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            18561..19007
                     /locus_tag="ACN3HL_001967"
     CDS             18561..19007
                     /locus_tag="ACN3HL_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HHC8006821.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            18991..19329
                     /locus_tag="ACN3HL_001968"
     CDS             18991..19329
                     /locus_tag="ACN3HL_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HHC8006822.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            19448..20008
                     /gene="rsmD"
                     /locus_tag="ACN3HL_001969"
     CDS             19448..20008
                     /gene="rsmD"
                     /locus_tag="ACN3HL_001969"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HHC8006823.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            20005..20496
                     /gene="coaD"
                     /locus_tag="ACN3HL_001970"
     CDS             20005..20496
                     /gene="coaD"
                     /locus_tag="ACN3HL_001970"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HHC8006824.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            20486..21529
                     /locus_tag="ACN3HL_001971"
     CDS             20486..21529
                     /locus_tag="ACN3HL_001971"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HHC8006825.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT         7320 a         3751 c         4741 g         5780 t
ORIGIN      
        1 atttttgtca cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg
       61 gtaaaatcaa aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag
      121 aaaaaacaag gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac
      181 ggaaggatca atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt
      241 gtgaatcgtt ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg
      301 agcaaacgtg gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca
      361 agaatcgatt ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa
      421 aaaataagag aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag
      481 atgccagatg agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta
      541 gcggaagaaa aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg
      601 tatttggaaa gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc
      661 ggtcagcaag caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct
      721 gtagagtcac cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta
      781 tttgggatac cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat
      841 aaaaataaat tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg
      901 atgagtcaaa aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt
      961 attgaagacg atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata
     1021 cgaacgattg atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa
     1081 acaacgaaaa tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg
     1141 caagaaatga tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt
     1201 aatgaagcaa ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga
     1261 ctgataagcg cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt
     1321 tactatgcct ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta
     1381 gtagatatgg gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc
     1441 agaatcaatt acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa
     1501 attctagaaa agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca
     1561 gcttggattt aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa
     1621 actaagaaaa aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg
     1681 caacaaaact gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta
     1741 gaaaatagaa aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact
     1801 aatgctgtta atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag
     1861 cttgtatttc tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag
     1921 ttttattcac tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt
     1981 gtgacaaatg gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa
     2041 tgcagatttc ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt
     2101 agtacctgat ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg
     2161 tgtattagac caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc
     2221 aactgctgga caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt
     2281 tcttcttcca ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca
     2341 agctttttta tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc
     2401 tctaccacca caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg
     2461 tttgaagaaa cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc
     2521 acaaggtgat ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt
     2581 ttatatccaa aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa
     2641 aacacttgca caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga
     2701 tccgcttgca gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg
     2761 accagtccta atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga
     2821 tccaacccgc taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat
     2881 ccgcttccgt aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt
     2941 catcgaagca actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa
     3001 acaaaaggtt tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga
     3061 acaaattgca atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc
     3121 caagcaatca cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt
     3181 ggtgaagatg ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag
     3241 ttcggagaag accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt
     3301 ttcggtcttg cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt
     3361 ttcgaagcaa tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc
     3421 actagaaatc tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa
     3481 ttgcattcgg ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt
     3541 ccttccaacc cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg
     3601 gttgttttcc tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa
     3661 gcttacgaag ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt
     3721 atcacatacg gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa
     3781 aatatatctg ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc
     3841 attcaatccg tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg
     3901 ggcgttgccg cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc
     3961 ccaatcggac gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc
     4021 tggttgccaa atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa
     4081 aagaagggac gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga
     4141 atcgcagaag gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat
     4201 gatacattac tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca
     4261 ggaacggtta aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta
     4321 gtagaaatcg atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa
     4381 tcccaaactc cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg
     4441 tcaagcgaag gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt
     4501 gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta
     4561 gaagttcaaa atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa
     4621 aacgtgattg ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat
     4681 gctcctggac acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa
     4741 aaagtggaaa catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta
     4801 ttggctatgc catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta
     4861 actgcaactg gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt
     4921 ggtccaagca gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca
     4981 gctcctgcag cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga
     5041 gacttggaag aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc
     5101 aacagtaagc atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta
     5161 tgggataatc ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc
     5221 ttgccatatg tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca
     5281 tctatcgacg atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca
     5341 actgatacgg atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg
     5401 tttgctattg cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct
     5461 gcagaagata tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt
     5521 tggtttacac cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca
     5581 caacaaccaa tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca
     5641 ttaagtttcg atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc
     5701 aaacgtcttt tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt
     5761 tggagatttt gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt
     5821 agctgccatc cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat
     5881 tggcggtgtt tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca
     5941 ccattatcaa gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact
     6001 agattttgca aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg
     6061 tgttggtttc ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt
     6121 agatgatcac acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa
     6181 cgcaatcatc gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg
     6241 tgtgttagat tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat
     6301 cggtggcggt gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt
     6361 aacgattctt gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt
     6421 agtagaagat gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga
     6481 agcagtcgat aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc
     6541 cgttactgct gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg
     6601 cttagaacaa gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg
     6661 acgtacgaac gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc
     6721 acacaaagcc agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc
     6781 tgtagattat aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg
     6841 tatgacgatc aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt
     6901 ttcagggaac ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac
     6961 gacgatcgaa gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat
     7021 ggtctctgaa ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac
     7081 gattcatcct catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg
     7141 tttaccaatc catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc
     7201 gttttgtttt ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc
     7261 ttggtttatt accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag
     7321 atgcaagaat atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta
     7381 atgaagatgt gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt
     7441 ttgaagactt atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg
     7501 ggacgggaat ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa
     7561 aaaaatccaa acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc
     7621 atatcaagtc ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa
     7681 caatctcgca aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga
     7741 attttctaat cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag
     7801 aagggtgtaa tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg
     7861 gcaccttgaa ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat
     7921 ccggcgttgg aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg
     7981 gaaaaggaat aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct
     8041 tatcggaagg cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc
     8101 gagaaattgc ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag
     8161 tggcaatctt gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg
     8221 cagcgggaaa tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc
     8281 ctttgacatt tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa
     8341 tcgcagacct tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat
     8401 aaaaacgagc aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga
     8461 aaaaagtctg ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa
     8521 aaaggagtta gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca
     8581 cgttgaccac ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga
     8641 cgcacatacg caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg
     8701 tatcacgatt ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat
     8761 ggatactcca ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga
     8821 cggcgttgtg ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt
     8881 gaaaaaagca ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc
     8941 ttctgctcgt cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc
     9001 agatgatgat cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag
     9061 cttgtcagat gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat
     9121 tgaaaaaatc cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt
     9181 acttgactac aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat
     9241 caaagtagga gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt
     9301 aacgaaatta tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg
     9361 agacttgatt gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt
     9421 ggatcatcaa gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt
     9481 cttagttaat aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat
     9541 tgaagaacgt ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa
     9601 ctctccagat gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga
     9661 aaacatgcgc cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga
     9721 aatcgacggt gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata
     9781 tatgggtagt gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca
     9841 tacaggaaac ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta
     9901 ttcaactgaa ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca
     9961 atatctgcca atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat
    10021 cgatacagga aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt
    10081 cgtagaacca ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa
    10141 tgatttgact gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa
    10201 agaccaaaca tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt
    10261 cttgaatgat gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat
    10321 tttagagaaa aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg
    10381 aagagagaaa ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc
    10441 tgtggagaag tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta
    10501 aaagactttt aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca
    10561 cgaaaggaga tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc
    10621 gggaagatga acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa
    10681 aaagaaatta tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga
    10741 agtgggaaat caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt
    10801 gtgtcccctt taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata
    10861 cccgccactt ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa
    10921 atcgatagac agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat
    10981 tttatccaag caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt
    11041 atctctcagt gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat
    11101 caactgccaa atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct
    11161 gctgacataa aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa
    11221 cgagaaaatc tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa
    11281 tatttaaaga tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta
    11341 gaccgtctct atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt
    11401 ctaaatgaga atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg
    11461 attgtagcga caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc
    11521 cattatcaaa ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga
    11581 gatggtcttt ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag
    11641 ttttttatcc agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta
    11701 aaagcgatga cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat
    11761 tttggcgaga caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata
    11821 gtagaagtaa cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac
    11881 tatggtaaac aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct
    11941 ttaggttttg gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg
    12001 atgcagttaa ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat
    12061 cctgttttga aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat
    12121 cgaaaggaac ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa
    12181 gtgctgcggg aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta
    12241 ttttcagatt ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg
    12301 cttcagataa aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct
    12361 cggataaaaa atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat
    12421 gaataaaaac aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat
    12481 aattaaggaa ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga
    12541 tccaagtatt aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca
    12601 gtctctgtat ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct
    12661 tttcccggca agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc
    12721 tgatgttaag tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa
    12781 tttatgataa aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag
    12841 gcatctatta gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat
    12901 catggtatat agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc
    12961 agtcattaac cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa
    13021 aatgaaaaca gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac
    13081 gattttgctg ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct
    13141 gcaaattgca ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta
    13201 cctgtctctg actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt
    13261 gaaacgtcca cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt
    13321 tggtaatgcg gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa
    13381 ttatgtgtat actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg
    13441 gctgatcaat atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg
    13501 atttgctatt taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa
    13561 cggctactat gccatgttca acggaggact atttggcagg ggattaggta acagtatcca
    13621 gaaaaaagga tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga
    13681 actgggagtg attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat
    13741 tgtccttgta ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg
    13801 cgcaatgttt ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt
    13861 gacagggatc acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat
    13921 ttgtgtcggc tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata
    13981 ataaaaaaag atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa
    14041 tcgctgtacg tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg
    14101 cagaagaaga tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac
    14161 aaggaaaaaa accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag
    14221 aatgcggagc tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg
    14281 cgcaacggtg cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata
    14341 tttttggaga taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc
    14401 caggcacaga tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg
    14461 gttatccgat tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc
    14521 acgatgaaaa gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct
    14581 ttggtagtga tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac
    14641 agattctcgg ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc
    14701 agcgccgtca ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac
    14761 gtcaaaaaat ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag
    14821 gtacagtaga atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg
    14881 tccaagtgga acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac
    14941 tgttgattgc tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa
    15001 ttaaattaaa tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact
    15061 ttttaccaga cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc
    15121 tggatgtcgg aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag
    15181 taaaagtatg tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct
    15241 tgaaagaatt tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca
    15301 cacatcctga attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat
    15361 tatttgaatt tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa
    15421 ttactgtgaa tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac
    15481 gtatgcctaa agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg
    15541 cgaagggtgc cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg
    15601 atacgacatt tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt
    15661 tcaagcagat tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt
    15721 gggggggagc aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt
    15781 tgagaaaaat tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa
    15841 atgccgttgg gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag
    15901 cagcgcaagg aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg
    15961 aaaaaagtat ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata
    16021 ctggcgatat caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg
    16081 caaaggaact agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc
    16141 ttaaaccgca ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa
    16201 tccatctgca tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa
    16261 aagcaggagt agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc
    16321 ctagcatgag cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga
    16381 ttgaaaatgc acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt
    16441 ttgaaaacgg cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac
    16501 agtattcgaa tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa
    16561 tcaaacaaat gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat
    16621 catctaaagt agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag
    16681 atatttatga aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag
    16741 gagaactagg gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag
    16801 gcagacctgc attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag
    16861 taaaaaaaga attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct
    16921 atttgatgta tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg
    16981 ttacattact ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg
    17041 tacaaatcga acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata
    17101 tcgaagggaa tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca
    17161 aagataattc gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag
    17221 aacaaattgg agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata
    17281 acgttaaaaa aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg
    17341 aagcacgttt tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt
    17401 ctggtgacct tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa
    17461 aagactgggt ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc
    17521 agtcttgttt ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca
    17581 aatgacaacg tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa
    17641 accgatcgat cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt
    17701 tggttttgaa acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat
    17761 ccaagacagc agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc
    17821 gttttattta gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt
    17881 cacttttgag taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta
    17941 tcgtccgcta attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac
    18001 aaacggccta ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata
    18061 tcaagtgttt ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc
    18121 aatcaatcgc gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga
    18181 cgaacttccc atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca
    18241 tgattttttg acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa
    18301 atcgctaggc agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa
    18361 gttaatcagt aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga
    18421 cgctactttt tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga
    18481 cccgggaacg gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca
    18541 agaagaaaac ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg
    18601 aggatcaatg cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc
    18661 ttgaacataa acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct
    18721 tgtctaagaa agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc
    18781 gtgaaaaaaa acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg
    18841 cagctttccg atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac
    18901 ttgccgaaga agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga
    18961 aaaaacactt tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata
    19021 acaaaacgac gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa
    19081 aagttcggct tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat
    19141 gaagagacat tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta
    19201 gaacgttctt accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca
    19261 gtattaaaag acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa
    19321 catctttaaa aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga
    19381 tttttgatca ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag
    19441 tgagtagatg cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg
    19501 ggcgaacacc agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc
    19561 atattttgat ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga
    19621 agcagtatct agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa
    19681 aatcatcaaa gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact
    19741 tgatgcggac aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt
    19801 tcttgatccg ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact
    19861 gggacttttt tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc
    19921 agaaactgtg gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac
    19981 tatctataga aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct
    20041 tttacaaaag gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta
    20101 attggtgttt ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca
    20161 ttgatcacaa aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa
    20221 ttgacggtag aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt
    20281 atcaaagact ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa
    20341 ttggaaactg tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta
    20401 aaagaagtac tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa
    20461 gctttagctg gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat
    20521 tatcatattt ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga
    20581 atcaccggga gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa
    20641 aggttctggg tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc
    20701 tttaaaagct aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg
    20761 ggcgacaaat gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc
    20821 agcaatcgaa caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt
    20881 atatgtcatg agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac
    20941 agtaacaaaa gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa
    21001 aagccaaaaa gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac
    21061 agcttctggt gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct
    21121 tactgaccat accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg
    21181 tgggccatca gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa
    21241 cttgcgacat ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg
    21301 ccgaatcgga ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt
    21361 ctttgcacca gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac
    21421 caactacgaa gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc
    21481 agtaaaaaca gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat
    21541 taaagagggg ttgtgacacg agttctgtca caacccctct ttttcgtcaa aa
//
LOCUS       DBGZHO010000048        21280 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.048, whole genome shotgun sequence.
ACCESSION   DBGZHO010000048 DBGZHO010000000
VERSION     DBGZHO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.048"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            132..506
                     /locus_tag="ACN3HL_001972"
     CDS             132..506
                     /locus_tag="ACN3HL_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HHC8006826.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="ACN3HL_001973"
     CDS             complement(620..1249)
                     /locus_tag="ACN3HL_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHC8006827.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="ACN3HL_001974"
     tRNA            complement(1383..1455)
                     /locus_tag="ACN3HL_001974"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="ACN3HL_001975"
     tRNA            1669..1742
                     /locus_tag="ACN3HL_001975"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1880..2044)
                     /locus_tag="ACN3HL_001976"
     CDS             complement(1880..2044)
                     /locus_tag="ACN3HL_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006828.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2339..3667
                     /locus_tag="ACN3HL_001977"
     CDS             2339..3667
                     /locus_tag="ACN3HL_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HHC8006829.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="ACN3HL_001978"
     CDS             3869..4702
                     /locus_tag="ACN3HL_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HHC8006830.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="ACN3HL_001979"
     CDS             4718..5455
                     /locus_tag="ACN3HL_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HHC8006831.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="ACN3HL_001980"
     CDS             complement(5610..6578)
                     /locus_tag="ACN3HL_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HHC8006832.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="ACN3HL_001981"
     CDS             6810..7643
                     /locus_tag="ACN3HL_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HHC8006833.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="ACN3HL_001982"
     CDS             7677..8516
                     /locus_tag="ACN3HL_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8006834.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="ACN3HL_001983"
     CDS             8542..9102
                     /locus_tag="ACN3HL_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8006835.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="ACN3HL_001984"
     CDS             9301..11022
                     /locus_tag="ACN3HL_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HHC8006836.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="ACN3HL_001985"
     CDS             11187..12329
                     /locus_tag="ACN3HL_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HHC8006837.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="ACN3HL_001986"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="ACN3HL_001986"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HHC8006838.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="ACN3HL_001987"
     CDS             14129..14776
                     /locus_tag="ACN3HL_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HHC8006839.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14905..15121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15169..17814
                     /locus_tag="ACN3HL_001988"
     CDS             15169..17814
                     /locus_tag="ACN3HL_001988"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HHC8006840.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="ACN3HL_001989"
     CDS             18124..19437
                     /locus_tag="ACN3HL_001989"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HHC8006841.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="ACN3HL_001990"
     CDS             19427..20080
                     /locus_tag="ACN3HL_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8006842.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /gene="radC"
                     /locus_tag="ACN3HL_001991"
     CDS             20135..20827
                     /gene="radC"
                     /locus_tag="ACN3HL_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HHC8006843.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="ACN3HL_001992"
     CDS             20977..21177
                     /locus_tag="ACN3HL_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8006844.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7183 a         3551 c         4445 g         6101 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcaggt
//
LOCUS       DBGZHO010000049        21247 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.049, whole genome shotgun sequence.
ACCESSION   DBGZHO010000049 DBGZHO010000000
VERSION     DBGZHO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.049"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(137..514)
                     /locus_tag="ACN3HL_001993"
     CDS             complement(137..514)
                     /locus_tag="ACN3HL_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006845.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            770..1498
                     /gene="purC"
                     /locus_tag="ACN3HL_001994"
     CDS             770..1498
                     /gene="purC"
                     /locus_tag="ACN3HL_001994"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HHC8006846.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1498..1752
                     /gene="purS"
                     /locus_tag="ACN3HL_001995"
     CDS             1498..1752
                     /gene="purS"
                     /locus_tag="ACN3HL_001995"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HHC8006847.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1754..2425
                     /gene="purQ"
                     /locus_tag="ACN3HL_001996"
     CDS             1754..2425
                     /gene="purQ"
                     /locus_tag="ACN3HL_001996"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HHC8006848.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2426..4648
                     /gene="purL"
                     /locus_tag="ACN3HL_001997"
     CDS             2426..4648
                     /gene="purL"
                     /locus_tag="ACN3HL_001997"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HHC8006849.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4633..6072
                     /gene="purF"
                     /locus_tag="ACN3HL_001998"
     CDS             4633..6072
                     /gene="purF"
                     /locus_tag="ACN3HL_001998"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HHC8006850.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6095..7147
                     /gene="purM"
                     /locus_tag="ACN3HL_001999"
     CDS             6095..7147
                     /gene="purM"
                     /locus_tag="ACN3HL_001999"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HHC8006851.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7144..7722
                     /gene="purN"
                     /locus_tag="ACN3HL_002000"
     CDS             7144..7722
                     /gene="purN"
                     /locus_tag="ACN3HL_002000"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HHC8006852.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7719..9254
                     /gene="purH"
                     /locus_tag="ACN3HL_002001"
     CDS             7719..9254
                     /gene="purH"
                     /locus_tag="ACN3HL_002001"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HHC8006853.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9270..10544
                     /gene="purD"
                     /locus_tag="ACN3HL_002002"
     CDS             9270..10544
                     /gene="purD"
                     /locus_tag="ACN3HL_002002"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HHC8006854.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10666..11580
                     /locus_tag="ACN3HL_002003"
     CDS             10666..11580
                     /locus_tag="ACN3HL_002003"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HHC8006855.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11713..13278)
                     /locus_tag="ACN3HL_002004"
     CDS             complement(11713..13278)
                     /locus_tag="ACN3HL_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006856.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13271..14722)
                     /locus_tag="ACN3HL_002005"
     CDS             complement(13271..14722)
                     /locus_tag="ACN3HL_002005"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HHC8006857.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14736..15752)
                     /locus_tag="ACN3HL_002006"
     CDS             complement(14736..15752)
                     /locus_tag="ACN3HL_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8006858.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTSDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15972..17060
                     /gene="chvE"
                     /locus_tag="ACN3HL_002007"
     CDS             15972..17060
                     /gene="chvE"
                     /locus_tag="ACN3HL_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HHC8006859.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17114..18640
                     /gene="mmsA"
                     /locus_tag="ACN3HL_002008"
     CDS             17114..18640
                     /gene="mmsA"
                     /locus_tag="ACN3HL_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HHC8006860.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18642..19847
                     /gene="mmsB"
                     /locus_tag="ACN3HL_002009"
     CDS             18642..19847
                     /gene="mmsB"
                     /locus_tag="ACN3HL_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HHC8006861.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20104..21081
                     /gene="guaC"
                     /locus_tag="ACN3HL_002010"
     CDS             20104..21081
                     /gene="guaC"
                     /locus_tag="ACN3HL_002010"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HHC8006862.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6813 a         3596 c         4822 g         6016 t
ORIGIN      
        1 ataaccaaaa aagaagcaga tccgttagcg gttctgcttc ttttagttta ttatattttc
       61 ttatcaataa taggaacctg attttaaaag cggctacctc tttaccgtgc ctctttacat
      121 acaaaaaata gaggaattaa gcgtaaatgg cttggctatt ataactaaaa tgctggttat
      181 ggagatgttg cagcaagttt tcgagaaaag cgtattccat ctcttgtcca ttgaataaga
      241 tctggatacg ataatgattt ttgaaacgct tctgttcatg aatctgactg attgaaagtt
      301 cgcctttgtg ttctgtctga taaagaaaag tccttttacg gcattcagca cagcgcttgg
      361 ttgctcggcg gatttttcgg aatgtataaa aactagtatc tttattgcat aaataaacgt
      421 ctttgatcga cagcaaatca ttatatagac aggaacgttc ttcagctgtt aattctgata
      481 aaaaaagctg accttgtttt attgcatctt ccatcggcaa gtgcctcctc gaacccatta
      541 tccaaatttt tagttaattc taatatacca tcattaagta taaatgtaaa cgcttgttga
      601 tggtataaga ttttcgtttc tgataaaaca cgaacattaa aagaatctaa tgccttaaat
      661 gtacatattt ttgttgattt ataaaaagat gattgctaaa atttaaagtg aaaaaacgaa
      721 caaaaaacga tgtatttgct tttaatgtaa ataaaaagga gagacgtaca tggagaagaa
      781 agaacttttg tatgaaggaa aagccaaaaa aatatatctt acttctgatg agaacttgat
      841 ttggatagaa tatttagatc aagcaactgc gttgaatggc gcgaggaaag accagataag
      901 tggaaaagga gaattgaata atcaaatcac aagtgcaatt ttccgttatc tgactcaaag
      961 aggaataaaa aatcatttta ttgaacaatt gtctaaaacc gaacaattag caaaaaaagt
     1021 acaaattatc cctctggaag tggttatccg aaatattgca gcaggaagtt tctcaaaacg
     1081 tctaggtgtt cccgaaggta aagaattcat caaaccaatc attgaattct actataagga
     1141 tgaccagttg gatgatccat ttatcaatga agagcatatc tatttcttac aacttgcaaa
     1201 gccggaagaa atcagtgagc tgaaagccca agcgttggct attaatgaaa ttttgaccga
     1261 attatttgct aaggtcggtt tggttttagt agatttcaag ctagaatttg gccggtcgaa
     1321 tggacaaatt ttgcttgcgg atgaagtaac accggatact tgccgattat gggatgaacg
     1381 tacgaatgaa catatggaca aagacgttta ccgcagagat ctaggtgatt tgatcccagt
     1441 ctatcaagaa gtatataacc gtctatcgga actaactgaa gaaaaggagc gagtatgatg
     1501 tatttcgtaa aagtatatgt aacctataaa gattcagtgt tagatcctca aggggaggca
     1561 gtaaaaaaag cagtccatcg tatgggatat gaaacaatcg aagatatccg aataggaaaa
     1621 tactttgaga tacaacttgc tgatgcagaa gaaccaatcg atacagtgat tgaaacgatt
     1681 tgtgacaagc tgcttgcaaa tgtaaatatg gaaacatacc gatatgaaat caaaaaaatg
     1741 gaggaagtat aacatgaaat ttgcggtcat cgtttttcca ggttcaaatt gtgacgcaga
     1801 tatgttatgg gcagttcgcg agatcatggg cgctgatgcc gaatttgtac ggcatgatga
     1861 gtcctcttta gaaggatttg atggggtttt actgccggga ggattctcct atggtgacta
     1921 tttgagatgc ggtgcgattg ctcggttttc tacaatcatg gaagaagtga ttcgttttgc
     1981 tgaagaaggg aaaccagtat tcggtacatg caatggattc cagatattga cagaagcagg
     2041 acttttgcca ggtgtactga gacgaaatga gtctttgcat tttatttgca aaactgtacc
     2101 attgaaagtc aaccccaaga cggcctttac ttcagagtat gaagccgacg aaataatcta
     2161 tcttccagtt gctcatgggg aaggaaatta tttctgtgac gaagaaacac ttcaagaact
     2221 aaaaaaaaat aatcagattg cctttactta taatgacaac atcaacggca gcgtggaaaa
     2281 cattgcaggg attacgaaca aagcagggaa tgtgttagga atgatgcctc atccagaacg
     2341 tgcagtagaa gacttgctag gatcagaaga tgggaaacgg ttctttgctt ccattttaaa
     2401 aaacttcgga aaggtgaccg tatagatgaa aacattgaaa gaaccgacag ctgaagagat
     2461 caagaaaaaa agaatctatg ccgaatgggg attgactgat gaagaatatc gaatgatcga
     2521 agaagatatc ttaggaagaa tgcctaatta tacggaaact ggactgtttt ctgttatgtg
     2581 gagcgaacat tgttcctata aaaattctaa accggttcta cgcaaatttc ctactagtgg
     2641 acctcatgtg ttgcaaggcc ctggagaagg cgcaggcatc gtcgacatcg gtgatggact
     2701 agcagttgtc ttcaaagcag aaagtcacaa tcatccttca gccgtggagc cttatgaagg
     2761 agctgcgaca ggagttggcg gaatcatcag agatattttc agcatggggg ctcgtccaat
     2821 tgcgttgcta gattcattga ggttcggcga attagataat ccaagaacga aatatttact
     2881 agaagaagta gttgcaggta tcggcggata cggcaattgt atcggcatac cgactgtagg
     2941 cggcgaaatt gcatttgatc cttgttatga aggaaaccca ttagtcaatg caatgtgcgt
     3001 aggtttgatt gaacacaaac atatccagaa agggcaagcc gctggcgtcg gtaattcgat
     3061 catgtatgta ggtgcaaaaa caggtcgcga cggtatccac ggagcaactt ttgcctcaga
     3121 agaatttaat caagaagaag aacagcaacg ttctgctgta caagtaggcg atccttttat
     3181 ggaaaagctg ctgcttgaag cgtgtttgga attaatcttg catcattcgg attctctaat
     3241 aggtatacag gatatgggag cagcaggact tgtttcatct agtgcggaaa tggcttcaaa
     3301 agctggctca ggacttatat tgacattaga tgaagtccca caaagagaaa ctgggatgac
     3361 accttatgaa atgatgttat cggaatcaca agaacggatg ttgatttgtg ttaaatcagg
     3421 agaggaagaa aaaatccaag aactatttca gaagtatgat ctagatgcag tcactatcgg
     3481 taaagtaaca gacgacgggc aatatcggct atatcatcaa ggagaagaag tagcaaatct
     3541 gccagtcgat gcattagctg aagatgcacc agtttatcat aaagaaatga aagaaccagc
     3601 tcgaatcgta gaatttcagc agttagctcc ttatcagcca gttatcgaag aacctggaca
     3661 agtattgctt gatctgctgc agcaaccgac gattgcttca aaacgttcaa tctacgaaac
     3721 ttatgattca caagtacaaa ccaatacagt tgtccgtcca ggaagcgatg ctgctgtgat
     3781 gagggttaga gggacgaata aagcgttagc tatgaccaca gactgcaacg cgcgctatct
     3841 gtatttggat ccaaaaatcg gaggacaaat agcagtggca gaagctgcta gaaatattat
     3901 tgctagcggt ggtaagccct tggcgatcac cgactgcctg aactatggtt ctcctgataa
     3961 accagaagtt ttttgggaat tatcgacttc agctgacgga attgctgctg cgtgtgaaac
     4021 gttaggaact cctgttattt caggaaatgt ctctttatat aatgaaacgg atggtcaagc
     4081 aatctatcca acaccaatga ttggtatggt cggattgatt gaggatcata aacatatcac
     4141 tactcaggaa ttcaaaaaat caggggatct aatctatata ttaggtaaga cgtttgcaga
     4201 ttttgatggc agtgaattac aaaagatgca gcttggaaga atcgaaggtg tgatccgaaa
     4261 ctttgatcta tccattgaaa agagaaacca agagttagta ttgacagcca tccaaaacgg
     4321 attgattgaa agtgctcatg actgttcaga aggtggcttg gcaattgcac tggcagaatc
     4381 agctttcaaa catcagctag ggatatctgt acagtttgaa ttgtcctctg ctcaattatt
     4441 tgcagaaact caatcaagat ttgtgttgac agtcgcaccg gaaaataaga cacgattcga
     4501 agaaatgatg ggagatgctg ctgttttagc aggtaaggtg acggatgaag cgataatcga
     4561 aatttcagca actgacggtc agatcaaaat agaaactgca gtagcaagaa agtgctggga
     4621 ggatgcaatc gtatgtctta tgaagtgaag agtttaaatg aagaatgcgg gatcttcggt
     4681 gtttggggtc atccagacgc cgctagtgtg gcatacttcg ggctccatag tcttcagcat
     4741 cgaggacaag aaggtgcagg tatcgtgtcc aatgatcgag gaaagcttaa ggggcatcga
     4801 gatttggggc tgctttctga ggtattcaaa gatcaaagaa aattgcagca gttaacagga
     4861 gaagctgcaa tcggacatgt acgttatgca acagcaggca atggaagtgt ggacaatatt
     4921 cagccttttc tattcaaatt tcatgatcag tcgatcggct tagcgcataa tggtaacttg
     4981 atcaatgctc gttcccttag aaaagagtta gaggaaaatg gggcgatctt ccattctaac
     5041 tccgatacgg agatattgat gcatttgatc cgacgaagtg aagaaacaga ttttttaaat
     5101 aaattaaaaa gtgctttgaa tgaagtcaaa ggtggctttg cctatttatt aatgacagaa
     5161 acggcaatga ttgccgcttt ggacccaaat ggttttcgtc cattagcaat cggacaaatg
     5221 aaaaacggag catacgtgat tgcctcggaa acttgtgcat tagaagttat tggggcacgt
     5281 tttataagag atgtccagcc tggtgagata gtgatcatca atgacgaagg aatccagatt
     5341 gattgcttta cgaaggacac gcagctttct atttgttcga tggaatatat ctattttgcc
     5401 agaccagatt caaacatcgc agggatcaat gtgcatactg cacggaaaaa tatgggacgg
     5461 aatttagcga aagaatcgcc agtaaaagca gatatggtcg ttggcgtacc taattcttct
     5521 ttgtcagccg caagcggtta tgcggaagct agtggaatcc cttatgaaat cggattagta
     5581 aaaaatcaat acattgcccg aacatttatc cagccaacgc ctgagctaag agagcaaggt
     5641 gttcgaatga aattatctgc tgtacgagga gtagtggaag gtaaaaaggt gattatggtc
     5701 gatgattcaa ttgttcgggg tacgacaagc agacggatcg tccatctttt gaaagaagca
     5761 ggggcaaaag aagtccatgt gaggattgct tctcctcctt tgaaatatcc atgtttttac
     5821 gggattgata ttcaaacgcg taaagaactc attgcggcaa atcacacgat tgatgaaatc
     5881 aaagaatgta tcggtgcaga ttctttaggt tttttaagtg aagagggtct gatcgaatcg
     5941 atcggtctgg aaaaagatgc tccgtattca ggattgtgta tggcttattt caacggagat
     6001 tatccgacgc cgttatatga ctatgaagaa aaatatcagg aatcactaaa agaaaaagta
     6061 tcgttctttt aaaagcagac caagaaggga gtatatgaat tcaatggcaa atgcatacgc
     6121 aaaagctggc gtagatgtcg aagctggata tgaagtagta gaacggatca agaagcatgt
     6181 caaaaaaacg gaacgtttag gtatgatggg cgctatagga ggattcggcg gttgttttga
     6241 tttatcggtc tttcaattaa aagagccagt ccttgtctcg gggaccgatg gcgtggggac
     6301 gaaattagca gtggcaatcg aagcagacaa acacgataca atcgggatcg actgcgtagc
     6361 gatgtgtgtc aatgatatct tagcacaagg cgcagagccg ttatatttct tagactactt
     6421 agcaacgggg aaaaatgatc cgttacgttt ggaaaatgta gtaaaaggtg tagcagatgg
     6481 atgtgttcaa ggaaatatgg cgctgattgg cggagaaaca gctgaaatgc ctggtatgta
     6541 ctcaggtaat gattatgatc tagccggatt tgctgtaggg atagctgaaa aatctcaatt
     6601 attgacagga gaaacgatca acccaggaga tgtgttgctt ggaatagcat ctagcgggat
     6661 tcattcaaat gggtactctc ttgttcgcaa aattttcttt gagcagcagc agttttcttt
     6721 atcatcaaaa ctgccagaat tgaaaaaaac acttggcgaa gaattgcttg agccaacgaa
     6781 aatctatgtt tcttccttgc ttccgctgat caaagaaaag aaaataaaag gagctgcaca
     6841 tatcactggt ggagggtttg tagaaaatat cccgcgaatg ttaccagaat ctatggctgc
     6901 acaaatcaaa cttggctcat ggccgattct tccaatattc ggctgtttac aaaaatatgg
     6961 tgaaattcct gagatggaga tgtatgaaat cttcaatatg ggcatcggta tggtcctggc
     7021 agtcgaagaa tcgaaagtaa aagaaatagt acacgaaatt gagcaagctg gcgaaaaagt
     7081 ttatgaaatc gggaaagtga tcgccaaaga aaaacatcgt gtggtgttta taggagaaga
     7141 acgatgagaa tcgctgtttt tgcttctgga aacggaagca actttcaagc gctagccgat
     7201 tatctatcga aaaaaggatt ggaatcttcg attgactggt tgttttgtga tcagcctgaa
     7261 gcatatgttt tgaaacgtgc aactgcgttg agtgtaccgg cagattgttt ttcacctaaa
     7321 gaatttgatt caaaaaaaga gtatgaagaa gcaattttgc ataaattgaa agaaaaaaag
     7381 atcgatttga tcgtattagc tggatatatg cgaatcattg gaccggtatt gctgaaaaat
     7441 tatgataaaa gaatcatcaa tatccatccg tctcttttac ctgccttccc tggtttgcat
     7501 ggcatacgtg atgcctttga agctggagta aaagaaacgg gtgtcacaat tcattatatc
     7561 gaccaaggtg tagatactgg accaatcatc cggcaggaaa aagtgagaat tgaacaggag
     7621 gacacgttcg attctttaga agaaaaaatc catagagtag agcatcgaat ctatccagaa
     7681 gtgattagtg aaattattga aaatggaggc tatctgaaat gacaagagca ttgatcagtg
     7741 tatcagataa aactgggatt gtagcattcg cccaaggttt gattgaacaa ggagtagaaa
     7801 tcatttcaac aggaggaaca aagcatgcgt tggataaagc tgggatcaaa acgctttcga
     7861 tcgaagaagt gacagggttt cctgaaatga tggatggccg tgtcaaaaca cttcatccta
     7921 aaatccatgg tggtctttta ggaagacgcg atctccctag ccatatggag gcaatggaaa
     7981 cggaaaatat ccaaccaatc gactttgttt gtgtcaattt atatcctttc aaagaaacga
     8041 ttatgaaacc agatgtcgaa atagcagaag ctattgaaaa cattgatatc ggtggtccta
     8101 gtatgctccg tagtgcagca aaaaaccatg aatttgtcac ctctgttgtt gatccatctg
     8161 actatgaaga agtactttca gaattacgtc agtatgggca tacttcactt tctttcagac
     8221 aaaaactagc ggcaaaagtc tttcgtcata ctgcggcata tgatgcactg atcgctcaat
     8281 acttaacgga ttgggtggaa gaaaaagaac cggaaaaatt gacacttacg tatgaacgaa
     8341 aacaaacgct tcgttacggt gaaaatagcc atcaagccgc tgccttttat cagtccgctc
     8401 ttctggaaaa atattcgatc gcagcagcaa aacaactcca tgggaaagaa ctttcttata
     8461 ataatatccg agatgcagat gctgcgctac ggatcatgaa ggaatatgac gagccaacgg
     8521 tagtcgcctt gaaacacatg aatccttgtg gtattgggac agcatctacg attttagaag
     8581 cgtgggaagc agcgtatgaa gcagatcctg tttcaatctt tggtgggatc atcgttttga
     8641 atcgagaagt agatctgcca acagcagaac agatgcataa gctgtttcta gaaatcatca
     8701 ttgccccttc ttatacacaa gaagctttgg aattactgca aaaaaagaaa aacatccgat
     8761 tactgacagt agactttgcg caggaagaaa atcaaaatcg agaagaaacg gtctcagtct
     8821 taggtggact tcttgtacaa gatcaagatc tggcaataga aaatgaagaa gagtggaaag
     8881 tcgtgacaaa acgtaagccg actccagcag aagcaaaagc attagcgttt gcttggagag
     8941 ctgtcaaaca tgtgaaatct aatgcgatcg tactggcaaa cgaacgtcag acagtaggaa
     9001 tcggagccgg gcagatgaat cgagtcggtt cagtaaaaat tgcgattgaa caagcgcaag
     9061 agaaaatgga aggtgcagtt ttagctagcg atgcttattt tccaatggat gattcggttg
     9121 aatatgcagc caaacatggt ataaaagcaa tcattcagcc aggaggaagc atcaaagacc
     9181 aagattctat tgatatggcg aataaatacg atctagcaat ggtctttact gatgttcggc
     9241 attttagaca ttagagagga gtcggataaa tgaacatttt ggtgatcggt gcaggtggtc
     9301 gtgaacatgc aataagtaaa aaacttttag ccagtccgaa ggtggatacg gtgtattgtg
     9361 cgccaggaaa tccggggatg acaaaagatg gtatcaattg tgtcgctatc agtgagcgag
     9421 atcattcagc gttaatccat tttgttaaga aagaggctat tgattggagt atcgttggtc
     9481 ctgaagttcc tttgttaaat gggatcgtcg atgattttat ggcggaagga ttgaaaatct
     9541 tcggtccgac aaaagcagca gctctgatcg aaggttcgaa aagttttgct aaacaattaa
     9601 tggatactta tcaaatcccg acagctaaat ccagaagttt tgaatgttac gaaaaagcag
     9661 cagcgtatat caaagaaaat ggtgcgccaa tcgtagtgaa agcggacggc ttagcagctg
     9721 ggaaaggtgt agtcgtggct accacagtga aggaagcgct ggatgcggca gaacaaatgt
     9781 tgaaccagca tcgatttggg gatagtagca aaaaaatcgt cgtagaagag tttttggcag
     9841 gagaagaatt ctcccttttg gcgtttgtcc gtaataccaa ggtgtatccg atggtcattt
     9901 cgcaagatca taagcgggca tttgataacg ataaagggcc aaatacaggc ggaatgggtg
     9961 cttattcacc agtaccgcaa atttcaaaaa agatgattga aaaagctgtg gaagaagttt
    10021 taaaaccagc ggctttggga atgaaagaac taggacgctc tttcacgggt gttttatatg
    10081 cgggtttgat tgctacgaag gaaggaccaa aagtgatcga attcaatgcg cgtttcggtg
    10141 atcctgaaac gcaagtcgtt ctttctcggt tgaagagtga ctttgcgcaa gtaatcgatg
    10201 atttattaga gaatcgtaca gtagagttaa agtggcagca agaaggatac aatgtaggcg
    10261 ttgtggttgc agctgccggt taccccgaag aatatgagac aggaatggtt ctaccagatt
    10321 ttctggaaga agagctttct gtttactatg ctggagtttc ctcaaataac ggcaaactag
    10381 ttggagcagg aggacgtctt tatttagtag aagcatacgg tgagacgatc aaagaagcac
    10441 agaaaaaaat ttacaccgcg ttaatggata aaacgacaga tggaacattt tatcgtacag
    10501 atattggaga aaaagctgcc aatagcgaac tgatcgtgaa gtaaatcagc tgcttccatt
    10561 tataaaaaat acaacaaaca taatcggaag cgccgatttt agtgaagcct tttcataaag
    10621 agtgtggtac acttttgttg tgtatataaa taaggaggag ttcagatgaa aaaaattcaa
    10681 ttaggtactt ctgatcagaa agcagctgca gtgatcttag gctgtatgcg tatcaacaat
    10741 gcggaagatc cagtaaaagt gattgagaca gcttatgaaa acggcattga tttttttgac
    10801 catgcagata tttatggaaa cggtgaatgt gaagaaatct ttgcagatgc tctagcaaaa
    10861 acatcaatca aacgagaaga tctttttatt caaacaaaat gtggaatcgt tccaggtgtg
    10921 atgtttgatt tttctaaaaa acatatcatt gaatctgtag aaaaaagttt gacccgtctg
    10981 aaaatggatt atgtggatgc tttacttctt catcgtccag atacattggt agaaccagag
    11041 gaagtagctg aagcgtttga tgaattggaa cggtcaggaa aagttcgtta ttttggcgtc
    11101 agcaatcaaa aaccaatgca aatcgaattg ctgaaaaaat atgttcgtca accattagta
    11161 gctaatcagc tgcaatttgg cttgaaacat actggaatga tcgatcaagg gattcatgtc
    11221 aatatgacag atgaagcaag tatcgatcat gacggtagtg tacttgatta ttcccgattg
    11281 catgatatga cgatccaagc atggtcacca taccagtatg gattttttga aggtgtattt
    11341 atcgggaacg aaaaattccc tgaattaaac caaacattag aagaactagc agctaaatat
    11401 caaacgacac caactggctt ggcttctgct tggattttac gccatccagc caatatgcaa
    11461 gtgatcgccg gtacgatgaa cgtagggcga atcaaggaaa tcgctcaagc ttcagaaatt
    11521 aatatgtctc gggaagattg gtacgaattg taccgtgctg ctggaaacat tttaccttaa
    11581 agattgtcat aagcaggtca aaagggctat aaattaaaaa gacagaataa cttgaaagct
    11641 gttttcagct tcgagatatt ctgtcttttt ttattgcaaa tggaaagagt atcattgtac
    11701 ggatttcgtt tattagttat ttttgttttt aaggaaaagc tgtgtccgat attcttttgg
    11761 agaaatccct tgttttttct taaataaata actgaaatag ttagggtcat tataaccaat
    11821 ttcaaaagca atatctgaaa tacgatagtc tgattgctgc aataattttt ttgctaattc
    11881 gattctttgt tctgtcagat aatcgatgaa tgtttggtta aacgattgag aaaaaatcgt
    11941 actgaaatga gagggactta atgcaacttg ttgagcgacc caagttaagg acatatctgg
    12001 atcggtaaaa ttttctttga taaaatccaa tgcatggttc aaaattggct gatatttgtt
    12061 ccttgaaggc tgtgagggca gagcagttaa gaaagaaatg aacatataaa ctgtcgaacg
    12121 gtaaagcgag tcgtcggcgc tgattgctaa gcgttgactg gtggatgtgc aatgaaccat
    12181 ttcttgcggg attttctttt ctttcaggca gacatgctgg agtagcttag tcaagacaaa
    12241 taaacgatat aatcgtgttc gagttggtgt gccttgtggt ttcgtcaagt gttcgatgta
    12301 cttagatact tcgtttttcg ataatgaaga caaatcaagt gagaggtcaa agtaaaagac
    12361 agaatcaact ggaagtttcg cttcttgaat caaatcctca tagctgataa tttgttcttt
    12421 aagggaactg gcggtttcaa gtatcatctg cgtgatctca aaagatgcag gtaattcgct
    12481 gattctttct gcgacaggac caatggcgac agaaaaatta tttttttgtc ccttttctaa
    12541 ttcatggacc aacgtttggg ctacctgata actggtctcg atcacatttt cttcaagaga
    12601 atcaactatt aaaaatttga tgaatcgaga ggaaacagca gagaagatca cttgttgatt
    12661 ctccctaaat aaaaacttca aataatcact gagatgagcg taatcttcaa agtctgtact
    12721 gacttggttt gctgctaata atacggtcat ttttttccct gctaaagagc gattgaaaga
    12781 ttcagcaagt ttcaatgttt cactgatcgt aagtgagcct ttgaacaaac cgttcaagaa
    12841 atgatttttt ttcaattcga aaacaagatc agaagaagtg tgcgtttctt tttgctgcaa
    12901 atctaaagca gttactgctt tttctattgc ttgtttcaat tcgctacttt taatcggttt
    12961 aagcagataa tcatctgcct gtacctggat tgctcctttc atataatcga aatcgtcgaa
    13021 tccactaata aatatgagac gagtccaagg aagtagtttc cttgcttctt ttgaaaaagt
    13081 caacccgtcc atgaaaggca tttggatatc agtcagaatg atgtcgggct gtaagtcgat
    13141 aattgaagac agtgccatct caccatctcc agcttcgccg acataagtga ttggataata
    13201 agaaccaagg acagttattt gttcccgcaa gttattgcga atgaggtatt cgtcttcgat
    13261 gataaaaact ttatacatgt ttgtttcctc caattgtttt gggagataga gggatcatca
    13321 gtgtgacagt tgttccttct cggtatttgc tgtcaatcgt gataggtttt tgatcatttc
    13381 cgtaataaag aaggagacgc ttgtttacgt tgtaaagtcc gtagccgata ctgaaatctg
    13441 aatcgatccc tttggctaac tctttacgta tttctgccag tttttctgca gggatgccaa
    13501 tcccgttgtc tataactttg aattggatca tctcatcaat tttgcatgtg gtaatacgaa
    13561 taaatccttt gtgacggacg tacttcgttc catggtatac agcattttca atcaatggct
    13621 gcaagatcat ttttaaaata gaaacaggaa aaagtgtttc tggtatatcg atcttatagt
    13681 caagcatatg gccgtatctt atttttaaga tgactagata atcattgata tggctaattt
    13741 ctttttcaag aggaatccag tcttgtcctt tgcttaaaga cgtacgaaaa aagccggaaa
    13801 gtgcatgggt catagtcaga gcttcttcaa agcagtcttg ttcgatcaaa gaaataatgg
    13861 catccaaact gttataaata aaatggggag taatctgagc ttgcaataca cgaacttcac
    13921 tttgtgctaa atggtattgt ttcaaagcgt tctcccgtaa agactggttt agatcttccg
    13981 ccattttatt catgctagcg gtaagtgttt gtaattccag tgtttccggc agggttaaac
    14041 gaaagccaag gttccctgaa gaaagttgtt ctgacatctc gatcagctga ttgatcggtt
    14101 cttggacctt tctctctaaa aagcgacgat tctttttcgc atagaaaaaa atggtactaa
    14161 gaactccaag ttccactatt gttaatagaa tgagcgagcg gacaagtgtc gtattttttt
    14221 tgcttgctaa gtcgatctcc acacgaacaa aatcttgtaa gatatctgac agcagttgag
    14281 tgacagaatc tacctgattg atgatctctt cattggtatc cataaaatct tttgccaaga
    14341 tattattgat cagctcgttt tgataatctt ccagtgtatc gatcgtacgt agcgatacat
    14401 ctaacgtact aatttcttta agtgtatttg tattattttt gatctctcga atatcattcc
    14461 taagttcttc taggatattt tcctcattga actcatctac ggttacttgg ccagaaatca
    14521 agtcccacat actttccaaa actttttgat caaccttcaa agcaattgca tctgcttttt
    14581 ggatatttgc gatcgtctgt tgataaatca aaagctgttg cgaatataac agtatgctca
    14641 gtagcaaagg gataacagca aatagaagca tggctttgtt tgcttgggca aaaatctgtt
    14701 ttatgcttaa attttttgtc atgatacttc tccagtcaat aatttctggt tgggatgtta
    14761 gctatattct gctgggaaaa gacagtctcg gaaataaaaa tatctttagg taatgttttt
    14821 cctgtttgaa tatttccaaa ataacgagta acggtattgg ctacatacca gccgacatca
    14881 ggtttacact cgactacaca attgacgatt cctgagcgta gcttctcgat catatcttct
    14941 tgtccatcaa tagttacaat gatcaaatct tctccaggtt tgattgatgt ttcttttatc
    15001 gcagctaaag caccgtgagt catttcatca ctatggctgt ataatacatc gatttcggat
    15061 aaatcatttg tttctaaata tcgtttcatc tggtcttttc ctttcatccg aataaaatca
    15121 ccgacaattc ggtgaacaat agtcatcgga ggtttatggt cgatggttcc atcttttttt
    15181 agggttggtt tacgattgat tgattccaaa aatccttcgg agcgtagctt ggtcggtgtg
    15241 gagttctctg aaccagcaag ttctaggatt ctgatttcct gtttctttga atttgtgaag
    15301 tgattgctga caaataaacc cgcccgattt ccttctgctt tgaaactggg gccaatgtgg
    15361 gtgacgaaaa gctcgggatc actcgtttga atatgtctgt cgacaagtat gacagggatc
    15421 cctgctcgct ttgcttcttt taatacagag tcccacccgg attcttgcaa aggagtaaaa
    15481 atgatcatat ccactttata ggcaatgaac gtccgtatat cttggatttg ccgttcctga
    15541 ttcatgtagc catttcggta gagaacttgg taatcttctt tttcaagcgc agtgataatt
    15601 gattcagtat gctttttccg ccagctactc tccgttcctg attgcgaaaa accaacgact
    15661 agtgggtcag gtgcttcctt tgtattaggt gtacacccca tcatttggta agcgattaca
    15721 acaagggcta aaaaaaataa aacacgtttc actttaaatc actccatctg gatttgttag
    15781 tactatctta tcagataaaa gggaaaatca aagtcaaaag gaatcaatcg aaaaaaatcc
    15841 aagaaactta aaaaaatcca agacaaaaaa agtacaccta aaaaatttaa agtaaatccc
    15901 ataaaaaaat caatgttaac gctttcttta ttagctatac tcggtgtatc aattgaaatg
    15961 ggggataaaa aatgaaaaac aaatttagaa agattgttgg gactatcgct attttgaccg
    16021 caagcattct attaagtgcg tgtggcaatt caggatctgc agatgatagt acggggtatg
    16081 taggaatcgc tatgccgacc aaatcagcag aaagatggat cgctgatggg aacaacatgg
    16141 tctcggaatt agaaaaactg ggttataaaa cagatcttca atatggagaa gataaagtag
    16201 aaaatcaagt agcacaaata gaaaatatga ttacaaaagg ggtagataca cttgtgattg
    16261 cttctatcga tggttcggct ttaactgatg tgttagctaa agcaaaagaa gcagatatca
    16321 aggtgatcgc ctatgatcgt ttactgatga attcagaaaa tgtcgattat tacgcgactt
    16381 ttgataattt tggagtaggt gtatcgcaag cagcttatat tgaagagcac ttaggattga
    16441 aagaaggaaa aggaccattc acgattgaat tatttggtgg ctcgcctgac gacaacaacg
    16501 cactaatcaa ttacaacgga gtgatgtctg ttttacaacc atatatggac aacggtcagt
    16561 tggtcgtgcc atctggacag acgagtttca gtcaaatcgc tacgcttcgc tgggatggtt
    16621 ctacggcgca agcaaggatg gataatctgt taagcgcaaa ttatactgac caaacattgg
    16681 atgctgtttt gtcgccatat gatccaataa gtttaggaat catttcgtca ttaaaaggcg
    16741 tggggtatgg gagtgaaagt aaacctttac ctgtgattac tggacaagat gcgacagttg
    16801 ctggcgttaa atcgatcatt gccggggaac aaacacaaac gatctttaaa gacacacgta
    16861 tcttagcaaa aaatacgatt gaaatgatca aagcaatcag tgatggagaa gaggttccgg
    16921 tcaatgatac tgaaacttat gataatgggg tgaaaactgt ccctacgtat ttagcaaata
    16981 cagtatctgt cgataaagat aattatcaag cagagctgat cgacaccgat tattataaag
    17041 aatccgatct gaaaaattaa gaggaaccaa acaaggaact aaagagatct aagtcagaga
    17101 gaggataaga attatggcgg attgtatttt aaaaatggca gatatcacca aaaaattttc
    17161 tggaatccga gcgttagatt gcgtgaatct gatgattgaa cgtggggaaa tccatgcatt
    17221 gtgcggagaa aacggagcgg gaaaatcaac attgatgaat gtcttgagcg gcttgtatcc
    17281 atatggctcc tatgacgggg aaatctttta tgatggaaag ctgtgtcaat ttaaagattt
    17341 gaaagatagt gaagaaaaag gcatcgtcat cattcatcaa gaattagcac taagtcctta
    17401 tctttcaata aaagagaata tttttctcgg aaatgaacaa gcagaaagag gcgtgattga
    17461 ttgggaactg acagaaaaga aaacatatga actgctgaat aaagtcggtt tgtctatcga
    17521 cccgaatctt ctagtatccc agattggcgt agggcaacag caactagttg aaatagctaa
    17581 agcattatca aaatccgtcc gtctgttgat tttggatgag cctaccgctg cattgaatga
    17641 agaagaaagc gcgaatttgc tgagattgat ccgagagttg aaagagcaag gtgtaacctc
    17701 catcattatt tcacataagc tgaatgaaat cgtggatatc gcagatcgaa tcaccatttt
    17761 acgggatgga cagacgattg agacactaga aaatgaaatg atcagcgaag agcatattat
    17821 tcgcggaatg gtgggcagag atttagttga tcgttatcct gaaagaaaac cggatattgg
    17881 agaagtttat tttaaagtag aagactggac ggtctatcac cctcttgatc acgagcgaat
    17941 cataaacgac cacatcaact tgcatttgaa aaaaggagag attgtaggaa tagctggact
    18001 gatgggagcg ggcagaactg aattcgctat gagtctattt ggacattctt atggaagcaa
    18061 gatatccgga cgtatattaa aggaaggggc agagatatca gttaagaccg ttccttcagc
    18121 cattgcaaac ggactcgctt atgtctcgga ggaccgaaaa tctttaggac tgaatctgct
    18181 gatggatatt cgggaaaacg tgacgctgag cagtttggat aaaataagtc aaaaaggagt
    18241 attagataaa gaaaaagaag taactgaggc agaaaatttc cggaaaaaga tgcgtataaa
    18301 aacaaactcc atccatcaaa ttgtcagtag tcttagtggt gggaatcaac aaaaagtcgt
    18361 tttatccaag tggctgatga cacaacccga tattcttttt ttggatgagc caacccgtgg
    18421 gatagatgtt ggggcaaaat atgagatcta cacgattatc gaagaaatgg cagcaaatgg
    18481 caaagctgtc tgtcttatct cttctgaact tcctgaaata ttagggatgt gtgatcgaat
    18541 ctatacgatg aacgaaggac gtattacagg agaagtctcg cgagaagatg cagatcagga
    18601 agtcttgatg aaattaatga cgaaagaaga ggtgggttaa gttggaacag gcaaaaaatc
    18661 ttacggataa aaaagagaaa aaactaaatt tgaaaagtag agcagctgat ctttttggtc
    18721 gctacagcat ggtgatcatt ttagcgggac tacttattgc gtttcaattg atgacggatg
    18781 gtattttctg gcgtccattg aatataacta accttgttct gcaaaatagc catatattag
    18841 tactagctgc agggatgtta ttagttgtgc tcttaggtca tgtggatttg tcggtagggt
    18901 cagtgatggc gtttgttggt gcaattgcgg gcatgatgat ggtcaatcgc caaatgaacc
    18961 cgtggatgac agttatcgca tgtcttgcag taggcgggct gatcggcgca tggcaaggtt
    19021 tttgggtagc ttatgcaggg ataccggcgt ttatcgtgac tttagcagga ttgctgatgt
    19081 ttcgtggact gacacaagtt gttctaggag gccaatctct agcacctttt ccagctgttt
    19141 tccaaaaaat gtctacgggt tatttaccag acttaagcga aggaagcagc cttcacttct
    19201 tgacattgat tttaggaatg atcatcacga tcgtgttagt tgttggtcaa tggcgaacaa
    19261 gaaatcgtcg gaaaaatcat ttatttgaag tggaatctcc aacagctttc ttggtaaagg
    19321 cggtatttac agcagtcgtt gtactaggaa taacttatat ctttgcctct tatcaagggt
    19381 atccgattat tttgatcatt cttggtttga tcgttgcagc atatgggttt ttgacaaata
    19441 aaacagtagc aggtcgacag atttatgcga cgggcggaaa tcgaaaagcg gctgaactat
    19501 cagggatcaa aacaaagcga atcacgttct gggtattcgt caacatggga gtcatggcag
    19561 ctttagctgg attagtttta gctgctcgat tgaatgcggc aacacctcaa gcaggtacat
    19621 cgatggaact ggatgcaatg gcggcagtat attttggtgg tgcttcgact tccggcggca
    19681 ttggaacaat catgggtgcg attgtcggtg gcttggtcat gggtgtattg aacaatggca
    19741 tgtcgatttt aggcgtcggg gtagactggc agcaggcaat caaaggattg atcttgcttt
    19801 tagccgttgt gctagacttg tataataaga aaaaacgaac aacgtaggag aacgccggtt
    19861 attcagaaaa aagactgtga caagacattt gtcacagtct ttttttcgct aaaagcgaac
    19921 attcattgtt tcgtttgtat agactaaaaa taatatatgt ttttttacca ttcgtataaa
    19981 ttctcttttt gctcttgatt tttttgctta attgagttaa attacatagg gcgctaaaaa
    20041 aagccttgat taaattaata atgttcgtgt tttgctggat gtgaacatca ggaggataat
    20101 gtaatgaaag tatttgatta cgaagatatt caattaattc ctaataaatg tatcgtaaat
    20161 agccgttctg aatgtgatac aacggtcaca ttaggtaaac atacattcaa aatgccagta
    20221 gtgcctgcca acatgcagac gattattgat gaaacaatcg cagaattctt agcggaaaat
    20281 ggttatttct atatcatgca tcggtttgat gaagcagctc gaattccgtt tatcaaaaaa
    20341 atgaaaaagc gtggattgat tacctcgatc agtgttggcg tcaagaaaga ggaatattcc
    20401 tttatagaga agttggcaga agaatcgcta aatcctgatt atatcactat cgacatcgcg
    20461 catggacatg ctaactcagt tattgatatg attcagcata ttaaaaaata tttgcctgaa
    20521 acttttgtga ttgccggtaa tgttggtaca ccggaagccg tccgtgaatt ggaaaatgcg
    20581 ggcgcagatg caacaaaagt cgggattggt ccaggaaaag tatgtattac aaaaatcaag
    20641 acaggctttg ggactggagg ctggcaactg gcagctctta gatggtgtgc gaaagcagct
    20701 cgcaagccga tcatcgctga cggtgggatc agaacacatg gcgatattgc aaaatctgtc
    20761 cgttttggtg cgacaatggt catgattggt tcattgtttg ccggtcacga ggaatctcct
    20821 ggcgaaacaa aagtcgaaaa tggaatcgtg tataaagaat actttggttc tgcttcagaa
    20881 ttccaaaaag gcgaaaaacg aaatgttgaa ggaaagaaaa tctggatcca acacaaagga
    20941 tctttgaaag atacactagt ggaaatgcaa caagaccttc aatcatctat ttcttatgct
    21001 ggaggaagag atctggaagc cattcgaaaa gttgactatg tcatcgtgaa aaattcgatt
    21061 tttaatggag acacaatcta aaaaataaat aaaatattag gatgttgtga aaaagttgtc
    21121 ctgcattaag taataagaac agccaaacaa aaatagttct ttatatgttt tgtttggctg
    21181 gaattattat cgcagataca agcttttgaa catcattatt cagaataagg gactgtgata
    21241 agatttt
//
LOCUS       DBGZHO010000050        20830 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.052, whole genome shotgun sequence.
ACCESSION   DBGZHO010000050 DBGZHO010000000
VERSION     DBGZHO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.052"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..205
                     /locus_tag="ACN3HL_002011"
     CDS             <1..205
                     /locus_tag="ACN3HL_002011"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006863.1"
                     /translation="PPDFLIAQVYLEVHLLVRYCSMGRLLNTEKMVFEHHLFKIKKDC
                     DTNFVTTFKCIPRAKKLSEEIQF"
     gene            complement(239..523)
                     /locus_tag="ACN3HL_002012"
     CDS             complement(239..523)
                     /locus_tag="ACN3HL_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006864.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(541..1431)
                     /locus_tag="ACN3HL_002013"
     CDS             complement(541..1431)
                     /locus_tag="ACN3HL_002013"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HHC8006865.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1451..1669)
                     /locus_tag="ACN3HL_002014"
     CDS             complement(1451..1669)
                     /locus_tag="ACN3HL_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HHC8006866.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1639..3339)
                     /locus_tag="ACN3HL_002015"
     CDS             complement(1639..3339)
                     /locus_tag="ACN3HL_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HHC8006867.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3606..4379
                     /locus_tag="ACN3HL_002016"
     CDS             3606..4379
                     /locus_tag="ACN3HL_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006868.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4460..5029)
                     /gene="thiT"
                     /locus_tag="ACN3HL_002017"
     CDS             complement(4460..5029)
                     /gene="thiT"
                     /locus_tag="ACN3HL_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HHC8006869.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5095..5197)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5203..6174)
                     /locus_tag="ACN3HL_002018"
     CDS             complement(5203..6174)
                     /locus_tag="ACN3HL_002018"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HHC8006870.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6268..7641)
                     /gene="glmU"
                     /locus_tag="ACN3HL_002019"
     CDS             complement(6268..7641)
                     /gene="glmU"
                     /locus_tag="ACN3HL_002019"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HHC8006871.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8144..8962)
                     /gene="purR"
                     /locus_tag="ACN3HL_002020"
     CDS             complement(8144..8962)
                     /gene="purR"
                     /locus_tag="ACN3HL_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HHC8006872.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9129..9953)
                     /locus_tag="ACN3HL_002021"
     CDS             complement(9129..9953)
                     /locus_tag="ACN3HL_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HHC8006873.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9926..10606)
                     /locus_tag="ACN3HL_002022"
     CDS             complement(9926..10606)
                     /locus_tag="ACN3HL_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HHC8006874.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10629..11567)
                     /locus_tag="ACN3HL_002023"
     CDS             complement(10629..11567)
                     /locus_tag="ACN3HL_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HHC8006875.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11812..12663)
                     /gene="ispE"
                     /locus_tag="ACN3HL_002024"
     CDS             complement(11812..12663)
                     /gene="ispE"
                     /locus_tag="ACN3HL_002024"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HHC8006876.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12817..15390)
                     /gene="mprF"
                     /locus_tag="ACN3HL_002025"
     CDS             complement(12817..15390)
                     /gene="mprF"
                     /locus_tag="ACN3HL_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HHC8006877.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15531..16337
                     /gene="proC"
                     /locus_tag="ACN3HL_002026"
     CDS             15531..16337
                     /gene="proC"
                     /locus_tag="ACN3HL_002026"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HHC8006878.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16416..17972)
                     /gene="rny"
                     /locus_tag="ACN3HL_002027"
     CDS             complement(16416..17972)
                     /gene="rny"
                     /locus_tag="ACN3HL_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HHC8006879.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18383..19432)
                     /gene="recA"
                     /locus_tag="ACN3HL_002028"
     CDS             complement(18383..19432)
                     /gene="recA"
                     /locus_tag="ACN3HL_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HHC8006880.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19541..20782)
                     /locus_tag="ACN3HL_002029"
     CDS             complement(19541..20782)
                     /locus_tag="ACN3HL_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HHC8006881.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
BASE COUNT         5930 a         4514 c         3589 g         6797 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttactta ataccgagaa aatggttttt gaacatcact tattcaaaat
      121 aaaaaaagat tgtgacacga attttgtcac aacctttaaa tgtattccta gagcaaagaa
      181 gctaagcgaa gaaatccaat tctgattatt tattgtattt ctttgttcag catccttgct
      241 aaaagcccat attggacaaa gtattcacta cacccatgat ctcatctttt cgagaacgtg
      301 ctttttctgt cggatcttct acctcttctg tgtcaattcg aacaataaat ttccgattca
      361 tcgtcacgta agcaccgtcg ttgatcaaaa taaacagttc gttctcatta tagtctgcac
      421 aggcatcttt ccatacgtca aagccgtttt tttcagaagg gatatcccgt ttaaccacag
      481 tttttccact taattcgtgg aacgttacgt cataatattt cattatctct acctctttcg
      541 tcattcaata ttttgtactt gttctctgat tttttctaag atcgtcttag actggacgac
      601 ttgattttta atttcgattg catttgattt ggaaccgatc gtgttgattt cccgattcat
      661 ttcttggatc aggaaatcta attcccgacc tacaggacat tgtgcttcga taagttcatc
      721 tagtttttgt acatggatcg ccagacgatc cagttcctcg tgaatatctc cgcgttccaa
      781 caagatggct agctccgtca acaaccgttg ctcatcgact ttcgctccaa gaaattcctc
      841 cagctttttt tgatacctta tttgaaattc cttttcatag atttctacaa aactatcgag
      901 tttttttagt acttctttga attcttcagt attctttttc aacactaaag ctaaagcttg
      961 accttctttt tctcgactcg cctcaataga atcaagtgcg cttttcaatg tatctagagc
     1021 taactgtgcc aattcttcca tgctctcttc cggtttttct tctaccgtta cgaagttttc
     1081 gtccagcgcg aagcgttccg ccatccgact aattgacact tgattttgac taccgtatcg
     1141 ttgttgaatt ccgtctgtca attgagtgat aagtgaatca atcaattccc agttgatgac
     1201 gatctgtttt tcgtttttgc caatataagc tagattcaca aatacttcga ttcgaccgcg
     1261 gcttaactgc tgtttaataa gctgacgaaa atcgttttca acaaagttca ggattttagg
     1321 acttcgtatt tgaacatcta gaaaacgctg gttgacactt tttatttcaa tatctaactg
     1381 atacgctttt gtttcgcgga tggctttgcc aaaaccagtc atacttttca ttcgacaggg
     1441 tccttcctca ttacatattt tctattgctt tttgcagttg ttcaaactct tcgttcgtca
     1501 atgtcaggcc tttccccatt ttttcatggt ctggcgccca atctcgaaga tcgaattttg
     1561 gcgggcgacc attccagctg actaggttca gttctttacg ccaccccttg ttgttttctg
     1621 acaatatagc gatttcttct acgatttcat atgaaaattc ttgtgccatg gttgttcctc
     1681 cttgagataa tataaatata ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg
     1741 ctgcaaacga tccttgcgtt ttccttgtag cagataatca aaataaacag ttttcgtgcg
     1801 ctcattttgt attttttgct ggtattttcg ataccttcgc cattcttcag tacttaattg
     1861 accaatttgt gccaataaat catccggcat actttttata tcttgttggc agatcatttg
     1921 aatcatcatg tctacttgat agatttcatt gggcagtaaa aaatgttttt ttgctaaaag
     1981 ttctagcatc gccaatccgc atgtctctgg tacgaccctg ttcttatata aattacgcag
     2041 tttttgccaa aattttatgc ttttgaaaaa agataattct aactgaattt cttttgttaa
     2101 gtaagacaaa aatcctcgcc agtatgttct tgcaggttta acagaatgaa atgtatacca
     2161 gttcccatag taatagccta atcgtttttt catttccaga tagcctaatt gtaaatttaa
     2221 ttggttcctt tggctatcaa aaagcagaaa gctgcctagt gtccacaatg tttgacattt
     2281 ccaatggata aaaatgtctg gcatacgaat ttttttcgct gggcctggcc cttgcacatc
     2341 tacgacaaat gcctctgttg ctcctttgtt aatcgcaata tcaataggta ttttgttgcg
     2401 atacccaccg tctgcatatt tattttttcc gatctttcga taagccatag cgggataaaa
     2461 tgaagcagag gcgagtatcc aatctggtat ttcttctgtt tttgtctgtt ggatatcagt
     2521 cactacttcc gctagttctg gcagtttagt agacaccgta tataaacgta ttttgggatt
     2581 atgtttgagt aaggacaaat ccaaattgtc tttgaccatc ttttccaatg gagcagaaga
     2641 aaccccgcct tcaattagtg ctgttttcgt catttggcgt ctttctcgat agaagcgttc
     2701 acgaaggtct tcaactgcag ccatttctgg taacgcaagc acttgtcttg tcgacagctt
     2761 tttccataaa ttcacagctt ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc
     2821 acctaccgag gtacctgtga taatctcaaa gttgatatca tgttccttca gcgcctgcca
     2881 cacaccaatc tgataagcac cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata
     2941 gaccagcttt ttatttaatt gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa
     3001 ccattcttct gatagaggag attgaaataa aaaacaacag ttttctttaa taaaaaaacg
     3061 agcgcaagct tccatatacc gaaaaaattt tttccattca aaagtttcac cttcaatcaa
     3121 cagattatta aaaataacat ctcctctact tttagcaata gtaaaataga cggtatattt
     3181 tttcgatact gctttaaaag cacattgctt ttttgcagaa cgccaaaaag cgtctctact
     3241 ttcttgatga ctttgaaaaa atggaagggg ttgttttgct tgctggatag gcgaatacag
     3301 cgacattttc tgtgaaaagt aaactttttt tatctccatc gcgctctcct ttttcttcaa
     3361 gtataccagt acgtcataaa aaggtcatga gtctcgtatt cgactttgta gattccataa
     3421 gaaaacaatt cataaaacct cctttaaata aaaaaataca aaaatcacaa aaattaattg
     3481 aaaatgagag tgttttcaat gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa
     3541 caagcttttt taatgcaaat gttgtaaaat aaaagagatt aagaggaaat aagaggagga
     3601 acatgatgac tgagtcagtt tatgtacata ttgataccac aagtaatgct gttttaacaa
     3661 aagggctgac tgctactgac tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct
     3721 tgcttgatcc atctgcttct gctggagaat atgaatccca tacagggctg aaagtaatcc
     3781 gtggtacaga aaatattcag cgtttctttt cctcttctcg taacaggcgt ggattcgatg
     3841 aattgaagtg gatcgacttt actgatttaa cgatgctgaa agaattgaca cctttagaaa
     3901 tttcagaatt attatatttt ggtcatatga aaacacatct tcattcgccg tttttttata
     3961 aactacagaa taattttgta tacttcgatc ttaatgatca gctgaatcgg atttattatc
     4021 gctatttaga tgaattttat aggatttttg ctagtaaatt aagttcgatc ttgtcagata
     4081 agatcaatgt aaaaaaatct tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg
     4141 aattattgaa agaaatgcgt aatttgatgc aggaagggat cattttttct tttgatcaag
     4201 ttggtttgat cgatggtaaa tatcgtatcc caatctatgt gattgaagat tatatttgga
     4261 aattaaaagg cacccggtat cgagaagagg aaatcatcgc tactttaatc tactctgtca
     4321 ccgatcgaca ctggcaattg gtagaagatg ccgatctttc ttatctgcca ttgaagtaga
     4381 tctatttctt atcaaaaaat aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag
     4441 tttcttgctt cttttttatt tacagctcct gtcgtttatc tggcacaaaa atcgaaggag
     4501 tcgtttgttg gatccctaat aaaacgatga tcgttacaat agctgtactc aacccgctgg
     4561 caccattcat tacgaaagaa aagagccaag gattcatccc ccatagtgca tacgctcccc
     4621 agaaaaccac tcctgcaata aaatgccaaa aatatctgga aagtgcgcca atcaatgcac
     4681 caaacacgat gctttttcta atttgtttcg tattatcgtc tacatagcct ttttggacat
     4741 ttgaagccat gagccctgct gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca
     4801 cttgaacgac acttaaataa taaacttgtc ccaacggaaa atgtaggatg ccccaaatga
     4861 aacctgccag catccctgcc tttgtccctc ttcttaacgc aaaaagagtc aatggaatct
     4921 gccctaatga aatagaaaaa ctgctgccga tctggatcgg aatcaacgac aacaccatcg
     4981 ctaacgctgc aacaatcgtt ccttctaccc aaactctatt ttttcccata aaaaaacttc
     5041 ctcctttgaa taaaaaagtc acaaaggagg aagcagcttt cgaaaatagt caaacagctg
     5101 tttattcaca attcctacgc tcgcataacc gatacaggta cgaagggttt agaaatagat
     5161 tcaatctcag cccaattgga ctcccctttg tgagtttatt tattatttat tttttgtttc
     5221 aaacaatgga ctaactggtt tgttttcatg gatacgtttg attgcatctc ccattagtcc
     5281 gccaacactt acttcatcga ttttgtcgat tttacgatct tctggaagat agatcgagtc
     5341 tgtaacaact agacgctcga tagctgaatc ttctattctt tgtaaagcag ggccggataa
     5401 tactggatgt gtacatgaag catacacact agttgcacca gcttctttca aagcattggc
     5461 agccaatgtg atcgtacctg ctgtatcgat catatcatcg atcagtacac aagttttgcc
     5521 tttgacttgt ccaatgatat tcattacttc tgcaacattt gcttttggac ggcgtttgtc
     5581 tatgatcgca atcggagatt tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc
     5641 atggtctggt gaaacaacga caacatcatc gcctttgatt cctttttcta agaaataatt
     5701 ggcaataagt ggcgcaccca tcaaatgatc gactggaata tcaaagaaac cttggatttg
     5761 aactgcatga aggtccaaag tcagcattct tgttgcacca gctttttgaa tcatgtttgc
     5821 tactaatttc gctgtgattg gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc
     5881 ataataaggc atgactacgt tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat
     5941 gatcagcaac tccatcaagt tatcattgac tgggctgctc gttgattgaa taacatagac
     6001 atgcgatcca cgaatacttt cttcaatgtt tacttgaatt tctccatcac taaattgagt
     6061 aacagatgat tttcctaact cgacgccgac tgctgctgca attttctctg ctaatgggcg
     6121 attggaattt aacgcaaaaa tttttaatct tgggtcaaag taatgttttg acatggggac
     6181 ctccactttc tttttcacaa ctctagaatt ctacctaata aatagtagtc atatttttta
     6241 aataaatcaa gtgattttgc aaaagtctta gtttagataa gggagttttt ttgcatatcc
     6301 ttctttattg acttgtcttg ctctcgcaat tgccagcgca tattctggaa tattgtctgt
     6361 aattgttgac ccggcagcaa tcgaactgtt tttagctacc tcgacaggtc cgatgatatt
     6421 cgtgctagaa ccaataaagc tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc
     6481 atagttgacg aagacaacac cacatccgac attgatttct tctcccagcg tagcatcacc
     6541 aacataagtc aagtgaccga ctttagttcc tttgccgatt tgagcatttt tcacttccac
     6601 aaagtttccg atatggacgt tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg
     6661 tcccacatct gcatgtttct tgacatggct gctttcaatg actgagtttt caatgacgac
     6721 gtgatcctca atcctactgt ctacgatttt tgaatgtgac ccgatgacac aatcagaacc
     6781 aatgactgta tttccttgga tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc
     6841 tacgcctgca tcgatgtatg tcgttgctga atcgacaaag cttacgccat tgaccatatg
     6901 catctggtta attcgctttc tcatgatctc atttgcttta gctaacgcga tccgatcatt
     6961 gactcccatt gattcttcaa aatcatccgt ttgataagca gcaactgtat ggccttcttc
     7021 ttttaagatt tcgatgatat ctgttagata gtattcacct tgagcattgt ttgttccaac
     7081 tttgcttaac gcatcgaaca aagcttcgtt gtcaaaacag taagttcctg tattgatttc
     7141 ttgtacaaga gcttcttctg gtgttgcatc tttttgttcc acgatttttt ctacgatccc
     7201 aatatggtca cggatgattc gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat
     7261 cgttgcactt gcattttttc cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt
     7321 caataatggt gtatcgccac tgataactaa cgttgttcct ttttttcctt ccaagaaaga
     7381 agcagcttgc aaaacagcat gtcctgttcc caattgttct gcttgtaacg catatttact
     7441 gcgttctcct agttgtgctt taacttgttc tgctccgtgt ccaacgatcg taatcacttc
     7501 atctggtttc gtttcactga cccgattaat gatatgttct accataggtt taccagaaac
     7561 gggatgtaaa actttatata attttgactt catgcgggta cctttccctg ccgccaaaat
     7621 aattgcataa cgtgcgtcca actgcgtcac tcctaaatat agtttgctga tttcagttta
     7681 tcccagtata cccatttttt caacaaaaca agtgattttc ttttatccca gcgttttctg
     7741 gataaaaaaa tagatagacc ataacgggcc tatctatttg gtaaccggtg ctctcctgcc
     7801 aactcctcgg tcacaagtca cactactcat aaaacatgaa aagctgtttt ttgaaatcgt
     7861 ttcttgtgac ttagagttaa acggtaggct tacaacctct tcattaaacg tttttcaatc
     7921 agctgacctt cggtattagc tcaataaacg gcaaaatatg aggagcaatt tttccgttta
     7981 ttgagctaat actcaggaca ggacgctgat ttcacaacct ctagataaac ggtgttcaaa
     8041 agccagtttc tcggtattaa gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa
     8101 atttttctta ctactcgaaa ctaagcagct ttttcacaac ctcttattct gaaaaataat
     8161 ttcctggcac aaccgtaata tttttcgttt gagtatctac atctttgaca taaagcagtg
     8221 acgtataatc atcgatggcg cgatgaccgt tgaattttga ttcggcaaat acagtgatgc
     8281 caacaagttc tgattcgaat tcttcaatca agctcttcat tccgttgact gttccgccgc
     8341 ctttcatgaa atcatccact acaaggacac gtgaaccacg tttcaaactt ctcttagaca
     8401 gttccatctt ttcaattctt tcagaagatc cagacacata gttgacactt actgttgatc
     8461 cttctgttat ttttgagtcc cggcgtacaa taacgaatgg cgcattcaga taataggaca
     8521 cagcttgggc aataggtacg ccttttgtgg ctacagtcat tacagcatcg attttttcac
     8581 caaggtattt agaagcaatg attcttccaa cttgacgcag cagttcaggt tctcctaaca
     8641 aatcagagag ataaacatat cctcctggaa gcagacggtc ttgttctgat agacgttctg
     8701 ctagagattc aatatatttt ttcgcctctt catatgaaat ttcagggatg aacaatacac
     8761 cacctgcagc acccgggatt gtttccaagg ttccataccc tcgttcttta aatgttttct
     8821 tgatgattcc caaatcttca ctgatagaag atttagcaga ttcataacgt tcggcaaagc
     8881 ttgttaagga aatcaattca tgcgggtgat tcaataaata ctgtgtcatg tcaactagac
     8941 gttcactgcg acgtactttc acctattcca actcctttta agaaatttta tcgttttaca
     9001 ttatataagt ttttcttcaa aaattcgagc attttatgaa aaaataagaa aatagttcgg
     9061 tatttattaa aataaaaaga agcctataaa aaatttttcg tttttataag gcttcttttc
     9121 tttataattt agttattttt tcttctgaag gcaaccaata ttcgtttgat gatatttaca
     9181 atcaggaaca aagcaataaa gactaatgtg attgttgctc ctggaggtgt atctagataa
     9241 aacgagctag ttagtcctga cagcatccct agaaatccta cacaaacact gatagcaatc
     9301 acgacattga agcttttgcc taatcgcata ccgattgctg cgggaagaac catgattgcg
     9361 gatatcaaaa gtgcaccggc aatcgggatc atcacagcaa tagccacacc agtaatcaca
     9421 ttgaacatca tcgacatcaa atgaacgggt agcccatcca cgtgggcggt atcttcatca
     9481 aaagtcagaa catacatcgg ccgtttgaat aaaaagaaca atataccgat ggcaacgaat
     9541 aagattccta aaaagatgac ttgctcccat gtaatggtca cgatcgaacc aaacagatag
     9601 gattggatac ttgttgctga attccctccg ctcaaattca tcaatactaa cgctagcgcc
     9661 aaaccaccag ccattaaaat ggcaatggag atttctgaat aggttcggta gatcgttcgc
     9721 agatactcca atatcacagc tgctaataca acgactagca tggtcgtaag tgtaggatta
     9781 aggttcaaaa agaatcctaa cgctacccct gctaaagaga catgagaaag cgtatcagcc
     9841 atcagcgatt gtcttctgat cactaaaaac acacctagca tcggggcgat tccggcaatg
     9901 aagatagcgg caagaaacgc tcttctcatg aattcatatg aaagcaacgc cattgagaat
     9961 cctcctttct caccagtcgg atctgtctgt ccgcatactg tttgatatct tcatgatcat
    10021 gggtgatcat tagaactgat ttcccatgga catgcgcact atgtcggaga agacgataaa
    10081 attcatttct ggattcttca tccatacctg ttgttggttc atcaagaaca aataagtcag
    10141 ggtcagtagc aaaaatacgc gctaaactga ttcgctgctt ttgtccgcca gacaattcac
    10201 ctattcgccg atttcgcata tcccacatcc ctacagcttc taaagcacgc tgtacatgtt
    10261 gatgatcttt ttcagagaga cgcttgaacc agcggcctct tggatatctt cctgaacgga
    10321 ctaattcgat caccgtacta ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat
    10381 aaccgatact taattttttt ccttcttgat ttttctcagc aatctttatc attccttttg
    10441 aaggtttcag taatcctaac gatgctttca ccaaggttga cttggctgct ccattttctc
    10501 cagttaaaat gacaaattca cccgcatcta catgataaga gacatcttct agtacaggtt
    10561 catcatcata gtaaaaggtc aaatcagata tttcgatata acgcacctta caacctccat
    10621 tctaaaactt aattgatact ttcttttaaa gctttcagat ttttttccat gacagaaata
    10681 taattttcgc ctgctttgat ttgttcatta gtcaagcttt ctaaaggatt caacacttct
    10741 agcttcactc ctgtttcatt cgacaatgtc tcagctacct tcgaagaggc attttcttca
    10801 aaataaatca ctttgatgtt gtttttcttc acaaattctt ttagctcagc taagcgactt
    10861 ggtgtgggtt cctgatctgg tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga
    10921 ttcgctaaat aagcaaaagc agcatgctga gtgacaaatg tgcggtttgt tgcatctttt
    10981 agctcatcgg agtatttttg atccagtgct tcaagctttt tgatataagc atcggcattc
    11041 ttcgtaaaag tttccttttt atctggatat ttttcgccta attcttcagc aatcgttctg
    11101 acttctttta tagctaatac cggatcgagc caaacatgtg gatcgtattc atgtgaatga
    11161 ccatgccctt cttctgattc ttcatgttcg tctgcttctt gcgattctaa acggtcgatt
    11221 cctttagctg cttcgatcat caaggtctgt ttgctatcca ctgaatcctt taacgaatcc
    11281 acaaaaaatt ccatgtctga actattatac acgaaaacat ctgcatcgga aatttctgct
    11341 ctttcttttg cacttggttc gaaatcatgc ggctccgttc cagcagggat caaaagtttc
    11401 acgtttcctt catcccctac gatctctttt gtaaaatcat acatcggata aaaagtcgta
    11461 acgatcgtca aatcctcttt tttgtctgct tccttgttcg tatttccaca tgctgcaaac
    11521 agtaaagcac ctatcattac cgtagctgtc aaaagatatt ttttcattta tatgctcctt
    11581 tcaatgaaca aatcggaatt ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa
    11641 aacacagtca atagaaatcc atcaatttct gatttaagca tgtatattct tgattaaatc
    11701 gtaaaatgga tgagttgctg ctcatatcta gccatttcac tacaataaaa aactgaagaa
    11761 taccatttta ggattcctca gtttttcatc acctatttta cttcttatat tttattgcag
    11821 ggttcgtact aaataaactt cctcacaaaa accttttaac ccattatata ctctctgcgc
    11881 tcttgaataa tgttgacaca aggcaaaaac ggttggtccg cttccactca tcaatgcagc
    11941 atctgctccg tacttgatca tacgctcttt gatttgatgg atgactggat gccgctttcc
    12001 cgttatatct tctaaactgt ttcccatttt tttgatcatc tgctgataat cttgctctcg
    12061 gatggcttca gcaagtccgt ggatgtcttg atgttggatg gcttgcgtat ctacttctct
    12121 aaacactgta cgtgtagaga cactcattct tggtttgacc aacacaaccc agcactgtgg
    12181 catagaaggt aatacttgga tttcttcccc tttgccaccg acaaatgccg tacttccgta
    12241 gacacagtaa ggaacatctg taccgacttc caaaccgatt tctgccagtt cttctaacga
    12301 acagcccaga ttccataatt ggttgatccc tcttagagca gctgcacagt ctgtacttcc
    12361 tccgcctaat ccagctgcta ctggaatatt cttcttaaca aagatcttga caccggtttt
    12421 gatattgtat ttatttttta gcaataaagc agcttgataa acattgttcc gttcatctac
    12481 cggtaaaaat gctttatttg tttctacaat gattttgtct tctgttattt cttcaaaaaa
    12541 tagatgatct gccaagtcta cgctcgacat caccatttcc aactcatgat acccatcttg
    12601 ccgtctatat aatacatcca gtcctaaatt tatcttggct ggcgcttttt caatcaattc
    12661 catcctctca cccattcgaa aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa
    12721 agtatagctt atgtctgcct agtggttgat tttgtcatcg tttcaacagc tttcacagaa
    12781 ttttctcttc ataatccaaa caagttctag tgattcttat aattctgtga gcacttcttc
    12841 tgccaaactc ggaacatttc ctttttcttt tcctatcaga ctgagtagct gcatggtagc
    12901 aaatccgaaa ttacttcctt tcctataagc aaaataacgt ccttcccaat gatcgacata
    12961 ttttaatttc ttttcataag cagactggaa ggaatagaaa aaattaccat aattatatac
    13021 gatatgcatg actttttctt gaaagaaaga aaaatctgtt tctccaacat tagctaatgg
    13081 agctaagcct agattggctt ccgagtagcc cattttctcg tatacaataa acagattggc
    13141 taacagatag tcagctaatt cctcagattc tttaggtaag acccgcaaca aatcatatcc
    13201 cgcctgcttc ttcgtcatcg gctgagcggt gatgaagcca acgacttttt gatctttacg
    13261 gacaataccg acaccgctag ataatacata tgatttatca aatcgtccca cagagaagta
    13321 tttttctcgt gcaccttgaa gccatttttg tgaaacttca tttacagctt gatgtaattc
    13381 ttccggcagt tgatcgtacc aagtaaaatg gtatccttct ttcatcaaac gttgatattc
    13441 aagttgctga ctcagccgag acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc
    13501 tactttcgtg aagtgaaaac ccaattcatg aagcatcact acgtagcttt ctgatatctt
    13561 ataaaacgca agctgatagc ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc
    13621 ccgcatcatt ttaggattgc caactggatc tcctaaaaca aagcatttgt ttcctttgat
    13681 ctgataacca aaaacgactt gatcttggtc gtcttcttgg taataaaaat aactgtaacc
    13741 tgacaagcga agctgatggc ttgtagctgt gcctccgtat gtttccaata aacggtcaaa
    13801 acggtctttt tcgtactcac tgccaagctt cgtagtatct tcagctaaat attgataaag
    13861 cgccactaaa gctagcaatg agatgcccaa accaataagc cctgagaacc acacatcatc
    13921 tgaaggaaac aaaataaaat gatttcctgt tattcgaccg actaaaaagc gtccgctgtg
    13981 atagcctgca attgcgtaaa cgataaacaa aaagccgaac aagctagcat caaagattat
    14041 agctccccaa gaataaacga attttgttcg ataaaattct tttctggata accacacagc
    14101 taacagaatc aagacatata ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt
    14161 taaaatacca aaagatagta aagcaatcgt aggcagaaat gcctttttga cttttactga
    14221 aagtgctcta gcaaggccga gtaataaaaa gccaaccaat agattcactg tctgatctaa
    14281 aaaattgaat gagaacggca ataatacttg aaatagccga ctgattgcag acagattagt
    14341 gattgttgat agaagtacca tcatgatccc cgcaaaatag acagcactta cgagcacgat
    14401 atgcgcaacc ttttggaaaa acagtcgcgg aatgttatct aaaaatcgat tgattttgac
    14461 tcctgtatgt gtgatgaaca atagaagtcc cgtcataaaa ggtagaacat aataaaacaa
    14521 ccgataatat aatagccaaa ctactgctac atcttgccga acaggcaatt gactcattcc
    14581 taagatcatc aaaacgtcaa aagtccccat tccacctggg accatcgtca gcattcctat
    14641 caatgtagca atcatgaaca taggatagat cgaaagcatc gaaatatcta ttctcatcaa
    14701 cttgccgatg atcaaaaata ccgcaagggc tcccgtccat tgtccaaagg atgccagtag
    14761 cagaccaagc aagccttttg gataaaactc gaagaacaat gtctttctct ttagataagc
    14821 aaaaaagaaa atgactggtg ctaaaaaact accgccgaaa agccagatcc aatagcttcg
    14881 aaaaatactt tctgactgaa taaaaaagac atcaataaat gtaagaaacg accatacaga
    14941 caaaccagtc agcataaata gtgcgacttt tgatacagtg gctaaaacca tttttctatt
    15001 tgtctgcttt ccataaaaac tagcccgcag acttgctcct accacaccac caaaaccggc
    15061 gagattgttg atcgtgtttg ttacccacgc agcaagaaga aactcttttc tttccatttt
    15121 tggttttcct tgtttttcta agactctgat cgtcacccaa tcatacaaca acatcggagt
    15181 gacacccagc agtccagcca gaatcatgag caggatcgtc atgcggcttt gttgtcccat
    15241 cctttgccaa atatcttgcc aactcatgcc attagcaata tttgcgactt gatttgccac
    15301 aaagactaac acggagccga aaaaaatcag ttttaaaatc agactatgtt cctttatcca
    15361 ttgcagcatc aagtatcgtt tatttttcac attttcccat tcctaacttg tatacttttg
    15421 tgtcataccc caatgttatc ttatttattt taatttttcc actttagacc tgttctttgc
    15481 ttgcgatgat agaaaaagaa agatatccta atgctaaagg agaggataac atgaaagtag
    15541 gatttatcgg cacagggaat atggcacaag ctattattga tggtttatta aaaaaaggaa
    15601 cagtctcgaa agaagaggtg ttcgtttcca gtggacattt tgaaaatgca caaaaatttg
    15661 ctgctgaaac tggcgtccat gcatgcaaaa gtaatcagga agttgcatca caatcagata
    15721 tcgttctttt agccgtgaaa ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat
    15781 atagccagaa agtcttattc atttctattg cttcaggaaa atcattaaca gatttagaaa
    15841 cagcgcttga agatcctcag gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg
    15901 taggagcagg cgtttctgcg atttgcaaaa atgaagctgc cacggaggaa cagcttcagc
    15961 aagctacgat gatttttgaa gcaatcggca gcgtctatcc tttagcagaa tcagatttca
    16021 gtacattcat tggccttgct ggcagctcac ccgcattcgt ttacatgctg atcgatgcga
    16081 tgggacggac tggtgtactg aatggtttgt ccaaacagac agccactgag attgctgcaa
    16141 aagcaattat gggttcttgt caaaaattcc tttcaagtga taaaaatcca tgggaacttg
    16201 tagaccaagt ttcttctcct ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag
    16261 caggattcat cccagcaatc atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga
    16321 tgttgaataa aaaataatga tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg
    16381 tggcttttgc cgcggctctt cttttgtatt ttttattatt tagcataatc agttgcacga
    16441 gtttcccgaa taacgattac tttgatgtgt ccaggataat ccagttcttc ttcgattcgt
    16501 ttacgaatat cacgtactaa acgaacagcg tctaaatccg agatttcttc tggcttgacc
    16561 attacccgaa cttcgcgtcc agcttgaact gcgtaacttg attctacacc ggcgaagctg
    16621 ttcgaaatat tttccagact tcttaaacga cggatgtagt tttctaatga ttcacttcgc
    16681 gcaccaggtc ttgctgctga gagcgcatct gctgcagcta caaggacaga gataacagaa
    16741 gtagcttcca catctccatg atgagaagcg atcgcgttga ttactactgg gttttctttg
    16801 tacttggcag ctaattccgc accgatctca acgtgagatc cttcaatctc atggtcaagt
    16861 gctttcccaa tatcatggag caacccggca cgttttgcta attggatatc ttcgccaagc
    16921 tctgctgcta agataccagc taattttgca acctcgaccg aatgcttcaa gacgttttgt
    16981 ccataactag ttctgaatcg cagacgtccg atgatcttga ttagatctgg atgaagtgta
    17041 tgagcaccga cttcaaacgc tgcctcttcc ccgtattcgc gaatacgttc atccatttct
    17101 ttacgagatt tctcgaccat ttcttcgata cgcgctggat ggattcgtcc atcttgtatc
    17161 agtttttcca aggtcatccg tgcgatttct cttcggattg gatcgaatcc ggaaagaaca
    17221 actgcttccg gtgtatcatc gatgattaaa tcgataccag tcagcgtctc aagcgttcga
    17281 atattacgac cttctcgtcc aatgatacga cctttcattt catcattcgg aagggtaacg
    17341 actgaaacag tcgtttctga aacttgatct gctgcgcagc gttgaatcgc taatgataat
    17401 aagtttttcg ctttgcgatc tgcttcttct ttggcacgct gttcagattc ttttaccatt
    17461 agagttaact catgattcag ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc
    17521 tcttttgata aaccagcaat tttttctagt tctttttgtt gatcttcaat cattttttca
    17581 acgtcttttt ctcgctcttc aattaattgc tgttttgaac taagtgcttc ttctttactt
    17641 tcaagtgagt tctcgcgttt ttctaacgag tcatctttac gattcagcgt ttgttcgcgt
    17701 tgaatcaaac gattctcttg agattttaat tctaacttac tttctctcag ctcactttca
    17761 acttcagaac ggtatttctg attttcttcc ttagcttcta acaatgcttc tttttttaga
    17821 gtttctgctt ctttttttgc actatcgatg attccagcag ctgatgattg tgcaccagct
    17881 atttctttct cgtgacgtga ctttgcgacc ataaacccta aaccaagacc gacaattaaa
    17941 ccgatgatag cgaggagaat gttgaatacc ataaaatcca cctccatact atctttttca
    18001 tttttatcat ctatacagct tctatgataa attattctaa actcgtcaat atgcatcttc
    18061 gcatatatgt gtacaaaaaa catgcacaac tttattctaa tgtttgtacc ccgtagtgtc
    18121 aactttaaat aaacaaagaa acggctttct acttattcat taaacgatgg tttttaaaat
    18181 aaatgacact agtttcatat aggtaaacct ttaaattgag aaacttttct attaaattat
    18241 tctttgtaga tgaacagata tttttatttt atgtacccac tcgtataatt aaataactca
    18301 cgatttcttt attcaataaa aaaacggcag gtcaaggaga gtacctactc ttcagaccag
    18361 ccgtttttgt ttatcataat ttttattctt ctactaaagg caattcttct tgtccttttt
    18421 catcttctgg gacagcgact tcttcaccaa taccataagc tgctctaact agagcagaaa
    18481 cttctgccat catttcagga tgattagcca tatagatttt agcgttttcc cgtccttgac
    18541 caatccgatc ttctttataa gaataccaag caccgctttt atcaacaatg tctttttcta
    18601 ctgccatgtc tagaagttct ccttcttgtg agatccctaa accatacatg acatctactt
    18661 cagcgatttt gaaaggaggt gctactttgt tttttacgac tttgatcttt gtacggttac
    18721 caacaatatc tgtaccttgt ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg
    18781 cgtagaattt caatgcgcgt cctccaggag tgatttctgg attcccaaac atcacgccta
    18841 ctttttcacg gatttggttg atgaaaatag cgattgtttt tgttttgttg atcgaaccag
    18901 agagtttacg caatgcttga gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca
    18961 tttcgccgtc gatttctgct cgtggaacta aagcagcaac tgaatcgact actacgatat
    19021 ctacagcccc acttgatact aaagcatcag cgatctctag accttgttct cctgtgtcag
    19081 gctgtgaaag aagtagttca tcgatattca cacctaattt ttgtgcatat tgcggatcta
    19141 acgcatgctc agcatcaatg aaagcggccg ttccgccatt tttttgtact tctgcaatag
    19201 cgtgtagtgc aactgttgtt ttacctgaac tttcaggtcc atatacttcg atgatacgtc
    19261 cacgggggta accgccgaca cctaaagcga catctaacgc aagagagcca cttggaattg
    19321 tagagatttg ttggtcgatt ttttcgccca atttcataat agagccttta ccatagctct
    19381 tttcaatttt tttcagtgca gcatctaagg ctgctttacg atcatctgcc aatacgataa
    19441 tcctccttat atttacaaat cagagcaaca tttcattatc cttatcatat cttttttagt
    19501 gaaaaaaagc aagaaaaaac cgaacaaata ttcgcattta tcattttctt aaaagctgtt
    19561 ttctcaaaag atcaaatcct tgcataaccg cattatatct gatagcagca cgatctctgg
    19621 caaagtgata tttttccgaa accacgccgt ctttagatga aatagcgatc catactgttc
    19681 ctgcagattg accttctaac gtgtccggtc cagccactcc ggtgaaagct acactgtaat
    19741 ctgttcttgc tatctcacgt gcttgaatgg ccatctgctc cacacattct ttgctgactg
    19801 ttccatattc tgctaatagc tccggatcaa tctccagaaa accagctttt gtttggagcg
    19861 agtaggtaac gaatccgcct ggaaatactt cagatacacc agcaatgtcg cctaatgcgg
    19921 cttggaaggc gccggctgtc aaactttccg ctgctgttac agtctgcttg ttttctttca
    19981 gtagttccac tacgactttt gctagcgaat tatcatcgcc gtatccataa aaatattccc
    20041 ctactcgttc ttggattttt tcttctaatg ctaaaagagc ttgattccct gcctgaacat
    20101 catttgtttt cactgtcagt cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg
    20161 ttggattgat ctgtgtctca atcagatctt ttagctcagt gaccagtcgc gattcaccaa
    20221 tcccataaaa gcgcaaaact ttagaaatta gtttttcttc agaaggaaaa cgttcctcta
    20281 gtaaaggacg tacttgttcc acaaacattg gtttcaactc attaggcgga ccgggaagaa
    20341 ggatatacgc atgtgtatct gtttgataaa aagtccctaa agcaagccct gtacgatttg
    20401 gtagaggaac cccgccttcg ataatctggg actgttgcag attgtttttg gtcatttttc
    20461 gatgggttgt ttcaaaatat gccaataatt ttttgtatcc ttccgtattt tgtatgagag
    20521 acttaccgag gtgagccgca gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc
    20581 cgccacataa gagtatgagt tcacttcttg tttcagctag agcaatcaac tcttctaaac
    20641 gctgctgatt atctcctaca actgtttgat aataaacttc gatacctaga tcagctagct
    20701 gttctgacaa gaaagtggca ttcgtattca cgacttgtcc tagtaaaagt tctgttccga
    20761 cagctattat ttctgctttc attacttccc gctcccttat atagtatacg ctgtattttt
    20821 atattttttt
//
LOCUS       DBGZHO010000051        20224 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.054, whole genome shotgun sequence.
ACCESSION   DBGZHO010000051 DBGZHO010000000
VERSION     DBGZHO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.054"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            194..493
                     /locus_tag="ACN3HL_002030"
     CDS             194..493
                     /locus_tag="ACN3HL_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006882.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(590..1024)
                     /locus_tag="ACN3HL_002031"
     CDS             complement(590..1024)
                     /locus_tag="ACN3HL_002031"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8006883.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1256..1966)
                     /locus_tag="ACN3HL_002032"
     CDS             complement(1256..1966)
                     /locus_tag="ACN3HL_002032"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HHC8006884.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1956..2816)
                     /locus_tag="ACN3HL_002033"
     CDS             complement(1956..2816)
                     /locus_tag="ACN3HL_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HHC8006885.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2821..3459)
                     /locus_tag="ACN3HL_002034"
     CDS             complement(2821..3459)
                     /locus_tag="ACN3HL_002034"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HHC8006886.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3474..3773)
                     /locus_tag="ACN3HL_002035"
     CDS             complement(3474..3773)
                     /locus_tag="ACN3HL_002035"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8006887.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(3816..5300)
                     /locus_tag="ACN3HL_002036"
     CDS             complement(3816..5300)
                     /locus_tag="ACN3HL_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HHC8006888.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5320..5781)
                     /locus_tag="ACN3HL_002037"
     CDS             complement(5320..5781)
                     /locus_tag="ACN3HL_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8006889.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="ACN3HL_002038"
     CDS             complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="ACN3HL_002038"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HHC8006890.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7084..7854
                     /locus_tag="ACN3HL_002039"
     CDS             7084..7854
                     /locus_tag="ACN3HL_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8006891.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8127..8954)
                     /locus_tag="ACN3HL_002040"
     CDS             complement(8127..8954)
                     /locus_tag="ACN3HL_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006892.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTEIDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9521..10756
                     /locus_tag="ACN3HL_002041"
     CDS             9521..10756
                     /locus_tag="ACN3HL_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HHC8006893.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11755..12015)
                     /locus_tag="ACN3HL_002042"
     CDS             complement(11755..12015)
                     /locus_tag="ACN3HL_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HHC8006894.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12042..13343)
                     /locus_tag="ACN3HL_002043"
     CDS             complement(12042..13343)
                     /locus_tag="ACN3HL_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8006895.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13635..14093)
                     /locus_tag="ACN3HL_002044"
     CDS             complement(13635..14093)
                     /locus_tag="ACN3HL_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HHC8006896.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14106..14936)
                     /locus_tag="ACN3HL_002045"
     CDS             complement(14106..14936)
                     /locus_tag="ACN3HL_002045"
                     /inference="COORDINATES: protein motif:HMM:NF023401.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HHC8006897.1"
                     /translation="MINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYD
                     KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYY
                     LYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDI
                     AISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVETITLRKPISDFHKGL
                     MEAQVAAEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK
                     "
     gene            complement(14949..15436)
                     /locus_tag="ACN3HL_002046"
                     /pseudo
     CDS             complement(14949..15436)
                     /locus_tag="ACN3HL_002046"
                     /inference="COORDINATES: protein motif:HMM:NF014148.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(15447..16889)
                     /locus_tag="ACN3HL_002047"
     CDS             complement(15447..16889)
                     /locus_tag="ACN3HL_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8006898.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16876..17640)
                     /locus_tag="ACN3HL_002048"
     CDS             complement(16876..17640)
                     /locus_tag="ACN3HL_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HHC8006899.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17744..18619)
                     /locus_tag="ACN3HL_002049"
     CDS             complement(17744..18619)
                     /locus_tag="ACN3HL_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHC8006900.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18874..18958)
                     /locus_tag="ACN3HL_002050"
     tRNA            complement(18874..18958)
                     /locus_tag="ACN3HL_002050"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18922..18924),aa:Leu,seq:caa)
     gene            complement(18976..19047)
                     /locus_tag="ACN3HL_002051"
     tRNA            complement(18976..19047)
                     /locus_tag="ACN3HL_002051"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19013..19015),aa:Gln,seq:ttg)
     gene            complement(19057..19129)
                     /locus_tag="ACN3HL_002052"
     tRNA            complement(19057..19129)
                     /locus_tag="ACN3HL_002052"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19094..19096),aa:His,seq:gtg)
     gene            complement(19191..19275)
                     /locus_tag="ACN3HL_002053"
     tRNA            complement(19191..19275)
                     /locus_tag="ACN3HL_002053"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19239..19241),aa:Leu,seq:caa)
     gene            complement(19296..19366)
                     /locus_tag="ACN3HL_002054"
     tRNA            complement(19296..19366)
                     /locus_tag="ACN3HL_002054"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19332..19334),aa:Cys,seq:gca)
     gene            complement(19412..19483)
                     /locus_tag="ACN3HL_002055"
     tRNA            complement(19412..19483)
                     /locus_tag="ACN3HL_002055"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19449..19451),aa:Gln,seq:ttg)
     gene            complement(19495..19567)
                     /locus_tag="ACN3HL_002056"
     tRNA            complement(19495..19567)
                     /locus_tag="ACN3HL_002056"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19532..19534),aa:His,seq:gtg)
     gene            complement(19570..19643)
                     /locus_tag="ACN3HL_002057"
     tRNA            complement(19570..19643)
                     /locus_tag="ACN3HL_002057"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19609..19611),aa:Trp,seq:cca)
     gene            complement(19650..19730)
                     /locus_tag="ACN3HL_002058"
     tRNA            complement(19650..19730)
                     /locus_tag="ACN3HL_002058"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19694..19696),aa:Tyr,seq:gta)
     gene            complement(19732..19807)
                     /locus_tag="ACN3HL_002059"
     tRNA            complement(19732..19807)
                     /locus_tag="ACN3HL_002059"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19772..19774),aa:Phe,seq:gaa)
     gene            complement(19843..19915)
                     /locus_tag="ACN3HL_002060"
     tRNA            complement(19843..19915)
                     /locus_tag="ACN3HL_002060"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19880..19882),aa:Asp,seq:gtc)
     gene            complement(19925..19997)
                     /locus_tag="ACN3HL_002061"
     tRNA            complement(19925..19997)
                     /locus_tag="ACN3HL_002061"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19962..19964),aa:Val,seq:tac)
     gene            complement(20013..20084)
                     /locus_tag="ACN3HL_002062"
     tRNA            complement(20013..20084)
                     /locus_tag="ACN3HL_002062"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20049..20051),aa:Glu,seq:ttc)
     gene            complement(20099..20187)
                     /locus_tag="ACN3HL_002063"
     tRNA            complement(20099..20187)
                     /locus_tag="ACN3HL_002063"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20151..20153),aa:Ser,seq:gga)
BASE COUNT         6337 a         4263 c         3210 g         6414 t
ORIGIN      
        1 agacgcagtg ttgacaattg aaaaaaaata aatgtttgta taccatatga ttatttcaat
       61 atgtatcctg gaattggaga tctcgtagag ctatatcaag atgaatcaaa tatacttgtc
      121 attcatcatg aaatatagag acttataaaa ttgtttattt ttataatgta tcagtataga
      181 aaggaaataa aacatggatt atactgttga atttgacagt gaactactta agcaatttcc
      241 acaagaagaa catttcatgt ataaagaagc aatttcccac aaagtgacag agtatttgga
      301 gcataatttt tttcgtataa agccagtgcg tactcgttcg gcaaaaggaa tatacgagat
      361 gaaagtcaaa attaataaaa aaaattatcg catagcattt gctttaaaaa aaaatcatgt
      421 gttcattttt tatattagtt cgaatttgca aaaaattgta tttgataaag aggtgagtaa
      481 aaaaataaaa tagctgagca ttggaggata gattgagtga tactaagtct atcctcttgt
      541 ttttctaaag aactaagcta gaattttttc ttttgtacgt tattatatgt tatttgtcat
      601 taccaaaaag cacctttttt cttctagtat ctatgacata agaaatacca cccatttcct
      661 ttacttgaac aaatcctact gattcataaa atttttttgt tttctcagta tcatctgtca
      721 ataattcgat ttggactggt ccataactag tgatcttctc caaagcttca ttcaaaagca
      781 ctttgcctat tccttggcgc tgatacctcg gatgaatgag gatatcttga ataaatgcga
      841 tcgtcgcaaa atcagtgatc caacgaacga ttccgataat cttcccttcc ccattacgct
      901 ttatcagaga ttcagattgt tcaaatgctc tagctaacct tgcagtgtct tttgtgtaat
      961 tcgtccaacc aacgctctta tataattcag aaatctcatc gatcataagg gaatcaatat
     1021 tcattttttt cttcctttct tatacaattc tccctctaat aatacagttc tttgactatt
     1081 taatctatca catataactc tcctgtaaag attctctcga ttccttaaaa tctctctttc
     1141 cttttagaat gcatcctttt tgataaataa aaaggttgtg ataaattttc ttcacaacct
     1201 ctgtttctct ctatcaagtg ttatctttta attttctacc cttaccctag catctctatt
     1261 gcccgtagta tgcatacttt ccatgtttgc gaaaataatg tttatctagt aaatattgcg
     1321 ggatttcaca tatattgggg ttgatcagct cgttttcttt ggccatcaga caaatttcat
     1381 ctaagatcaa actgttttct actgctttca taggtgaatc cccccatgtg aacggtccat
     1441 gtccatagac aagtactcca gggacttcgt ttggatctaa ttttctttcc ttaaacgtct
     1501 cgacaatcac attccctgta tgaacttcgt aagcttctct tacttcttct ttcgttaatt
     1561 ggcgtgtaca aggaacctta ccataaaaag catcagcatg agtcgtgcca taagctggca
     1621 aatcgcgtcc tgcttgcgcc cacatgacgg agtgcgtgga atgagtatga gtaatagcag
     1681 ttatatcttc aaaagtttga tacaaaacaa catgtgtggg gagatctgaa gatggtttta
     1741 agctatcttc ttctattata tttcccgaca aatctgttac caccatttga tctgcttgca
     1801 tgcattcata tctgacaccg cttggcttaa tgacgatgac tcctagctca cggtccactt
     1861 cactcacatt gccccaagtc aatttgacta atccgtatcg cggcaatgcc agatttgctt
     1921 caaggacacg ttgcttcatt gctgcaattt tttcttcaca agacatcata gccagcctcc
     1981 ttcaatttag aacttaagta gtcttttgcc tgctggattt ctcttcgaaa gtcttggctt
     2041 ttttcactcc acatttcaat cagaaatgtt ccatcataat ctagacgttt caaatgtctt
     2101 aataatccaa gaaaatcaac acaaccgcta ccaaaaggaa catcacgaaa ctggcctgaa
     2161 tattcttttg ttacagggta agtatctttt aagtggatag cagtgatata atcgatccct
     2221 ttctcaagtt ctcgagccgg attattttcc ggccatgcgg acaaattgcc taggtctgga
     2281 tatacttgta gaaaagggga atgaatctgt tctttgattt ctaaaaattt tgaaatggag
     2341 ttcataaatg gatcatccat gatttccacg gaaagaatga tgccatattt agaagcttcc
     2401 tttacgcttt cttttattcc ttcgataaag tcttctctgg aattcattga tttctcttca
     2461 taataaacat cgtatccagc tatttggatt actttgacgc ttagattatg cgccaaatgg
     2521 attgcttttt tcattagttg tttcgctgct tttttctttt ctggatcagc agaaccaaac
     2581 ggaaatcgcc gatgcgcact taaacaaatc gaatggatac gtacaccgga gctgaacatc
     2641 tcttctctca gctcagctat cttttcttca gaccaatcta atcgtgctaa ccgctcatcc
     2701 gtctcatcaa tcgacatctc gataaaatcg aagtccattt cttttacaag ggaaaaacgt
     2761 tctttccatg aaatatcttt gggtaatgct ttttcataaa tcccaatttg agccatttcc
     2821 ttacccccag atacgaatga tctcatcttt gaagttttgt gcggccttca tcggatcatt
     2881 tgctgctgta ataccacgac cagtgataaa ggtatacaca tcgatccctt caaataagtg
     2941 taatgtgtgt ggatttaatc caccagttac agaaacatta aagcctagtt caatcagttt
     3001 tttgatcttc gataaatctt tttcacccca agtttcacca gataacagcg catcacggct
     3061 ttgatggtag attacctgcc ggataccgat gttatgccaa tccatggctt gttcaaaagt
     3121 ccaattgccg tagagttcta cttgcaattc acctatttct ttttgtgctg cctccatagt
     3181 tggaatcgtt gcacaacaaa tgactgtcat ccagtctgct cctgcttttg caacattact
     3241 cgccactgtt cctccagcgt ctgcacattt cgtatcagcg actagttttt tatctgggaa
     3301 catactgcga atacagcgaa tcgctttttg tccttcctgt aagcaaagaa ttgtgcccac
     3361 ttcaataata tctactacat caccaacttt cataacatct cctaatgcat gttctaagtc
     3421 attgtgatct aacgcaattt gcaaattcgg cctgctcatc ttagttcctt cctttacttg
     3481 tttttttggt accactttgt ttcagcaaat ttttcactga tttctttggc tgacatcaca
     3541 tttttgatac cgataactgt aacttctttt ttctctgcct gagtaaacat attcaaaaaa
     3601 ttgactggcg taaaaactac atcgtattgg ccagctgaac tttttccctc tgaaatggca
     3661 caatgatgga ttttggtaat tggtacgttt agttctttca ttgctttttc cacacttctc
     3721 atcatcatca agcttgttcc tgatccattt gcacacgata ctaaaattct catcttaatc
     3781 cctccattat gagtgttgtc taatcagatt ttcttttata ctctctgctt ttctgcatat
     3841 gtgtcatagt cttctacaat caaaaaataa ccctcaggat ttttccgata ttgtaactgc
     3901 ggaatagcca ataaaccaat gacaactacg gcaattccag cataacctag gactttcatg
     3961 attactgtaa acaatggcca agctgttgcc cagtcgaaca tcccgatata accaccatat
     4021 gttgacatcc caatccatgt agcgaataat gctgaaccgc ctacttgtat gattcctgaa
     4081 agaaacggga acaggcaagc ggctttgaat ccacctcggt tattggcata aactgctata
     4141 acggcattat caaagaacaa cggaatgaaa ccggctatga cgatcgttgg tgatttcaat
     4201 aaaatcagta aaccaatcat caaaaactgt cccaaagcac caaacaagaa cccaatcgtt
     4261 accgcatttg gcgaaccaaa gccaaaagta gcagctacgt caattcctgg aacagctcct
     4321 ggtaaaattg tgtttgagat tccttggaaa gattgagtta gttcatcgac gaatgtccga
     4381 acacctaatt gcaagatcgc cagatatacc gcaaaattta aagaagtcgt cataatgtag
     4441 aataagaaac tctgtccttc ttgcatgaat tgcgcttgaa tcaaataatc tttgcctagt
     4501 acaatcagaa tgatcccaaa gaaaaatagc atgagtaacg aagtagcaac catattctca
     4561 ttgaaaatcg acaagaatcc tggtaatttg atatcttcga tttttttgtc ttgcttgatt
     4621 gatctatttt tcttttcatc ccgctttttc atccactcag ctaattttgc aaatataaag
     4681 attccgaaca tttgctgatg tgccactgca aatccggcac cttctgtcaa ttcctgcgtg
     4741 attcctactg ttaagttaga agctactgcc caataacaac ctaaaatcag tcccataaaa
     4801 atcaatactt gtatcctacc tagatcagga aagcaaaaca gtaaaatcca aaaagcggta
     4861 gctgcttgtt gaacctgaac gtttccggta gtgaaaacgg aacgcagttt cgtatatttc
     4921 tgaaaacgga ctaataagat atttaaaaca aatgcaatca gtaataaaat catcacatct
     4981 ccaaaggtac ggccaaatgt ctccattaat ccagcatcca cagcattttg tccaaaataa
     5041 ggatctgtaa ccatggcatc caaattgaac cgttccttta gtccaaccaa aatcggccga
     5101 aaattattga ccaaaccacc agagccaaca gtcaaaataa agtaaccgac cgttgccttt
     5161 aagaatccag cgatgcattc atgaagcggg cgtttcagca aaatatagcc taataacacg
     5221 ataaaaccaa tcaggtatgc tggctgcgtc aagatatttg ttgcaaaata cgtccaaatg
     5281 cttaacaaaa attcccccat cttttttctc ctctatcaat taattatatt ctgccatcac
     5341 aacttggtaa tcatcgatgg agttcgtaga gatgagacgc tcaaccaatc catctgtcat
     5401 taataattcg gataattttt ggatattttc tagatgttct tctggatctt ttgctgcaag
     5461 tgtaaaaaac aaactagccg ttttctcctc atcctcccct tcactttcaa aacggattgg
     5521 ctgtttcaac ttggtaaatg aaatagctgt tccaaaaaca ccatcacttt tttctgaaga
     5581 atgcggcatt gctacttgag gtgcgatcac aatataagga ccgtattttt ctacacaatg
     5641 gatgatctcc tccacatacg tttcatcaat aatttcctta tcgatcaata caagacagct
     5701 ttcggcgata gcttcacgcc aatccgtgat ttctttatct gggtaatgaa tcaattgatg
     5761 gtcaaaaaag tatttcagca agaaactccc cttctttctt ataaaaacga cggaaacggt
     5821 gtatcatttt caatcgagaa gacatcttca aatcctcgat aaaaattaaa ctcaagatca
     5881 tctttgtttg tcggatagat gaatttcccg cctacttgcc agatataagg tttaaatcca
     5941 tacttcaggc gatccttttt gaatttccaa atttcagtga tctcttttga atcagccata
     6001 aaattagacc aaatatcgta gtggacagga atcactactt ttgcattcaa tgactccgcc
     6061 atgcgcagca tatcaacaga agtaactttg tctgttatcc ctcgtgggtt ttcaccatag
     6121 gcccctaaac agacatcgat tttgtgttca ttaccatgtt tggcaaataa attggagtaa
     6181 tgtgaatctc ctgcatgata aagattccct cctgatgttt cgaataaata gtttactgca
     6241 atttgatcca tctcctgagg catttttcct tttaatacct cttctggatc ttcacaagtg
     6301 accaacgctg tccgatcaaa cgcttctaaa gctactacat tgatgtcttt gattttgact
     6361 gcatcacctg gctttactgt aatcgttttt tcttcaggaa ttccccattt ttgccacgtg
     6421 cgaaccactt cttttggccc aatgaatgtt gcttcaggac aattttgatg aactgctgcg
     6481 gctgtatgga tatctagatg atcggaatgg atatgtgtaa cgattaaagc gtctacattt
     6541 tttatcgcaa aaggatcgat tacgaaaggc tgagtacgta aattaggctg catattttga
     6601 acgccactca tacgcatcat ctgatggcct tttttcatca tgccattccc atgactacgt
     6661 tttcccgtcc cacaccatag atcacataaa atattcgttc cttcatgact tttcagccaa
     6721 attcccgtac agcccagcca ccacatagca aaagttccag gatccactac ttctgtttcg
     6781 atttcttcat tcaagtatgt gccccactca ggaaatgttt ctactaacca cttttctttt
     6841 gttacttcat tgacagtttt actcatttgc ttgctccccc catatcgttg ttccaactta
     6901 caagtaaata ttaatgtgta tcagcatcca tggaaaccct tttatatgac cgtttgtttt
     6961 ttatatgatt ttctttcagt aatcaatgat tgtttcagta taataaagac agatatgaat
     7021 gtttaaatga acaactagtc aaataaatcc atggatcaag atgtccctca ggaggcaaaa
     7081 gtcatgaaaa actcacttgt caatattgaa aaacgtcaaa aagaaatttt ggaactgctt
     7141 cagcagactg aacaactatc aactttcgaa ttagctgaat cccttgatgt atctattagt
     7201 acgatacgaa gagatttaaa tttattagaa gaaaaaaacg agatcatacg caattacggt
     7261 tattgttctt ataattacaa aaaccagact gattttgatc aatctggtcc tgaaaggatt
     7321 aaacaagcga ttgccagaga agctagtaaa tacattaacg attatgatac gctgtttatc
     7381 aattctagct cgactgcgtt gaaaacactg gattttcttc aatctaacca tttgacagtc
     7441 attacaaaca acgtgaaaat caattactct ccgcacaaag ataattgtag ttatatttta
     7501 actggtggag agatgcgctt tccaaaagaa gcactagtgg gcgacatcgc attaaatacg
     7561 atttcttcag tcaatgcaga catttgtatc attggctgta gcggagtcga tgtagtacat
     7621 ggggtcacaa caaagatatt aaatgaatca acgatcaacg aaatgatggt caacaagaca
     7681 atcaaatgta agattttagt cgctgatcat cgaaaaatcg gactgacatc aaagttcaag
     7741 attgctgata tttcagtctt tgattatttg atcactgata aattttgttc tgaaaaagta
     7801 ttagaggaga tcagaaatac ggggataaaa accattcaag tagattcatt ttaagaacca
     7861 ggacgtaaat atgtaaatag gattatcaaa aaaatgaata acaaatttat cgataaatga
     7921 aaaacacgct acgctcaaat tgataaagga atcccaagat gtgtccatcc aatcgatacc
     7981 atcataatct attgcttctt ttataaccgt tatatgttgc ctaaatagga atcaaacaat
     8041 atcgaaaaaa ggaggtatga caaaagtcac acctcctttt ttcgaataaa cggtattcaa
     8101 atcagaacac tgatttcaca accactttat ttcaggtcgt tttcaatcac ctttaccgcg
     8161 taatcatttc cgttgaaacg cgctattttt tttgcgtcca tatatctttc taaataatca
     8221 tcttctccta attgcttatg gcaagaagca atttcataaa gcaagtattc caatgcataa
     8281 gtcgatttat gtttcttatt atactcaata cccttctcac ataattggat tgctttatca
     8341 taatcctcga ttttacggta ataggtggcg atatcataat atacaatgca gaccatcaga
     8401 ttatcaaaat cagtctcact caatatttta agtgtacgct ccacataaac tttcgcaaaa
     8461 tctaattctc cttttgacaa gtagatcatt gccacgtttg cagctgcttg taagtgatgg
     8521 atatctattt cggtcgtttg ttccaacact tgattaaaat aaaataatgc tgcatctggt
     8581 tttttcgcat aaagatgatc aagcagtcct tgataaaata aaatttgatt taaaagatca
     8641 gaattactta ctttttcctg atcgatcgtt tgtaaaattt tataagattc ttggtatttt
     8701 gatacagaat tcaatgattg aatctcattt atttttttcc tgattttgtc ttcttctgtt
     8761 tctactaata tatcggagat ctcgacattc agctttttgc aaagcgcact taagatattg
     8821 atgcctggcg acatattctt gttttcgata ttgctgacag ttgcttgttc acaaatgcct
     8881 tctgctaatt gtacttgtgt taaccccttt ttctttcggt attcttttag taatgctcca
     8941 tctactttaa tcaaaacaat ttccttccct ttaaaaaatt atttctcctt tatatcatac
     9001 acaaaaaaaa gttctaaaca accaaaaatg tttagaacag aataaaaatt ttaattttaa
     9061 aataatattc aaattaaaca actggcgtat ctgctccttg atttcttttt gtgttatctg
     9121 aataattatc gtttacagtt ataacacata gtgaaaattg tcatggcgag aaagtctaag
     9181 aatattttta aacataacta tttctttctt acgtgtgtat aatgacgaca gcacacctat
     9241 caattaatat aattatttta ttttttatgt tctcatgttt atttttaatg acacaacttc
     9301 tcgtatttat ctggcacaac atataaatcg atcaaaaaat tgttgcgtgt ttttttgaaa
     9361 attggagttt caacttgatt acaaaattta aatttagaag ttgtgaaaac agcgagagac
     9421 agtttaatat tcaaaatata cataggctac tcgaacgctg tgttttttag tatactagta
     9481 agaaacgaag ggatagactc attccaataa ggaggatttc atgaagacaa ttctttttgc
     9541 tcctgcagta ttcaatttag ctgagacaac acgaatgatt gaggttgcca aagctatgaa
     9601 agaccgttat tactgtgtat tctttggctt ttctaaaact tttgctcctt tgatcacaga
     9661 aagtggcttt gagtatcatt tactagcgcc gatccttacg aaaaaacaag aagaacaaat
     9721 cataaaattt gaccagttgc gtacacttaa aaaccctttt accaaagaaa tggttgcctc
     9781 tcgtatcact agtgaacaga gtctgattgc taagtttgag cctcgactga ttgtgacagg
     9841 ttcgaatgtg acaatttttt tatcggcccg caataaaaag attcctttag tatatgttaa
     9901 accctatgct ttgagtgaac ctttttttca atcagagcat gcgctgatgc cccacgagtt
     9961 acgtttcttc ggccctttaa gcaatcccct ttggcactgg acaaaaaagc gtatagtaaa
    10021 tacccgatgg atccccaatg ccttcaaaca cgctgcacaa aaagaaatgc ttcctttacc
    10081 aaaaacaagt ttacaaatga tggatgctga tctaaatctc atcacaacgc ctaaactatt
    10141 tttggaagaa gaacagctgc cggaaaatta tcgaatcgtt ggtccaattt ttgctaagct
    10201 cagtacttcc ttgcctgaag aagtgctaac ttttatacag cgaaagcaac aagaaagaaa
    10261 acgtattatc tatttcgcaa tgggtagttc aggcaatccg cgtatgttac gcaaaatttt
    10321 gttcttctta caaaaacaac cggatctagc ggttattgca cctattgact atctgcttga
    10381 tgacattcaa tctgactcag aagatctttt aataacagaa tatctgtcta gtcatctttt
    10441 gcatgaattc attgattttt cttttatcca cggcggggaa gggaccgtcc aaactgcctg
    10501 tgaatccggc aaaccgttta tcggtgtggg gatgcaattt gagcaaagct gtaatattga
    10561 ctattgtgta aaatacggaa acgcaatcgc cctcacaaaa ccagtgactg aaagaaaact
    10621 gcagattgct ctgcgcgaag tttcttcacc caagattcgt cagcaggcac gcacgctgca
    10681 agccgttttt ccaataaatg gtccacaaca agcaattcaa gaaatcgaaa ccttcctgag
    10741 caaccaccca atatagtttc aagtagaaaa agctttttta atagagactc atcagtaatt
    10801 tcgctattcg agacccagac agtgaaaata caaaaaaagt aaatagtgga ttgaaaagtt
    10861 agagttactt aaattacggt gtctaaaaaa cacaaaatca tccttaaaat aaaagatctg
    10921 acgcaatcca aatgagcata ggtagcgtct gccatttatt cttagtcaaa ttctttgaca
    10981 cctttctctg gttggatcat ctcaacgttt cttcaaaaga aagaccataa taattaggca
    11041 aatacatttt cttaaaatgt gtcatataga tctagaagca tcgctttgta gagatttgtg
    11101 ctgctagtcc cttcaacaat tactaaatca aatgtaggat ttaccacttt atctttgata
    11161 atcaacctcc ctcttctgtt gagacaatga tctcgcaatc cgatgcatac tcctatataa
    11221 actgccagca atccccacat gctgagtaga tcatgtcaga atgttctatg tcgtcagcaa
    11281 cgataaacta aaagtcacgt tcaccatgac tgattgctat tcccagcgca attatttcta
    11341 tacacgtttc atgatttgaa taaacactct catcatacat attaccattc atacaccata
    11401 ctgcagcccc tactatatgg ttgtaagctc ccaaatctat atttgccttg atcactttgg
    11461 tagtagatcg actaattctt aatccattgc tgataaaatt ttcatttttg cctccttctt
    11521 tctgccaaaa cagttaaaac aataataatc tttatgtaaa aaagggctgt gacaaaagcc
    11581 ttgtcacagt cccatattcc gaataaacgg tggtcaaaag cttgcatctg cggtaataag
    11641 ttcaaccaaa cgaaaaataa gccaacattt cacaaaaatt taagaagcaa ttttcgtaaa
    11701 tttcttctta tttcttgaag ctaaccactt ctgtcacaac cacttttaga acatttaaag
    11761 cttcgatgtg acaaaccatc tatgctgctc gatcataaaa ttgatagcaa aaattccaca
    11821 aagtacatat gtcccccatg aaaacaaaac attcatatgc ggtacaatga tctttggaag
    11881 aatcacgatc aaaaatgatg ccagtgccca aatccatcga ttgatttgaa tatgatatgt
    11941 agctagcata ttcaatataa ggtgactagc cgttaataaa aagataaaaa caaaaaataa
    12001 aatcagccaa tacattgttt cccaccttct aaaaaccaaa cttagacagt ttggacttcg
    12061 ttttctccac gactttgttc atctgacagc atctttttat cataagcttt tacaaatgga
    12121 taatagataa taaatgctat caatgtgttg atcatgatca agataacaac acgccagtca
    12181 tttcctgctg aaagataacc gccgattgga gctggtaatg tccaagttgg caaaacagta
    12241 aatctattga ccatttctaa tttgactgca aaataactga taatagtcaa aactaaagga
    12301 actaagttga acgggatgaa catgtaagga ttcaacatca taggagctcc aaaaatcatg
    12361 ggctcattga tattgaagat accaggaata atagaaaaac gaccaacctc tttcaagaat
    12421 tttgatttac agaagaatat aaacaaaaca gataccacga tcgttgctcc tgcaccacca
    12481 attgttaccg tccattgata aaactgttca ggagcgatat agggtaattg ggtggcagct
    12541 gtaccatctg ccaatgcctt tgcattctca tccaacatga tcagccacat tggacgaaca
    12601 acagccccta caatactcat gccatggata ccaaatgacc acaacaaatg gatcaaaaac
    12661 attggtagta aaacaccaag caaattattc cctaaaatat tggttaaagg ctcgaataac
    12721 gataataagg tagcgtttac atcaaagccc gcgacgcttc gaatcagcca agtaattgtt
    12781 aaaatgactg cacctggaat caatgcctca aaactacggg caacagcagg tggcacttgt
    12841 tctggcattt tgatagtaat atttcgattt ttaaagaaac gatatacttc cactgcaaaa
    12901 atcatagata agatccccgc aaacatccca gatgctccca aagaactcat aggtaagacc
    12961 cagccaagag gtgccttttc aggagttaaa acgtttacag gaacttgtaa cataaagaac
    13021 gttcctaaag ataatatacc acctgtcaca ctatctaatc catatgattt agctagatcc
    13081 gaacccataa caaaagttgc ataaatagcc atcaatccca tcgtcatcct aaaaggtaaa
    13141 acaatcgttg ccgaataagg ggcaataaat tcattccatc caggaaacgg taaattgata
    13201 aagaccataa aaaatgtccc aatcaaaatc aatgacaatg ttgaaacaac cccattacga
    13261 attgctaata aatgacgctg tgtaccaatt tttgccattg gtgggacaag tttctcttcg
    13321 acccatttca tcagcttttc cactaaaacc actccttttc aataaaatat gaaccattca
    13381 ttgcatgaca acgcaaagaa tgttcataac taattatata attaagaaat tttatttcaa
    13441 tatattctct taaataatca aatttatttt taagaatcct gaaaataagt tttctaaatc
    13501 ataggagcaa caaaaaaatt cgataattaa caaaaatcaa aatgattaaa tctagtgatt
    13561 gaaacttatc atttcaaaaa aattttgtaa attcacccat aaatatcacc ctatttaact
    13621 tttttcatcg tacactaaaa ttcaaaacaa ctatctttaa tctttacttc ttggttttgt
    13681 tttaataaat ttccttcaaa aatgcctgga gaaactacaa tgatcaccgt atctttttgt
    13741 gcttgctcca acttcttcaa atctataata gctaacagtg tcccttcttt tacctcctgg
    13801 ttactttcaa cccgtatctg aaacggactt ccttcgagtt caactgtatc taaacccata
    13861 tggatcagta tttttctgcc agattcactt tcgatcgtta tggcatgtcg ggtaggaaat
    13921 atattatcga ttattccttt aactggcgca tggatatatc catcatgatt cgttatagcg
    13981 tatccaactc ctatcatttt tgaagaaaag acctcgtctt ttactgctgt taatggaata
    14041 atttgaccac tagctacagc ttttagaatg tttcttgttt taaagaaatg cactttttat
    14101 cacctctact ttaatgctgg ccaatatttt ttgtttactt tgatcatttc atctagtatt
    14161 ttttttgcga ctctggcatt tggtacggtt tgattcaatg taaatgcttg taaagctttt
    14221 tgataagaac cttcaaagta agcatctact agtaacttct ctgctgcaac ttgtgcctcc
    14281 atcaatcctt tatgaaaatc actgattggt tttcttagtg taattgtctc cacaccagtt
    14341 gcaccaacat atgccggtat ttcaacaact gcatctgacc gtagattcgg aatcgcccct
    14401 tgattaggaa cgattagcat aaagcgacga cgatcatcat tcaacaagga aatagctata
    14461 tcgacgatat attgtccatg ctccccaaaa ttaaagttca atacttcttc cacaataccg
    14521 cggcgtattt tatcagccat ttctttggta tttttctctc gtccatccat gaccatatta
    14581 gcacgtgtat actctttgtc agtatgctca acgaccatat caggatataa gtaatactct
    14641 aagtaattat tcgggatatt acttggaaaa tttttcgtga tgactgacat catttgaaag
    14701 gttttttgcc aagttttgtc tcctatatta aaatcggcga cttgcatttc ttttgttatt
    14761 agtttttcaa taatctctgg cataatttct cgttgcaatt ctttatcata aatcgatgta
    14821 taccagccaa agtggtttaa accataatac gtaacgatcc aattcttacg atcataaccg
    14881 taattcactg caatcgtttc ttcaattgaa atagtcatat cacaggcatt aatcattttt
    14941 acattcggat atttacgacg aacagcttca gaaacgatcg actctggatt tgtataattc
    15001 aaaatccatg ctttgggggc atagtcttgt atatgatcga caatttccaa taaacctttg
    15061 attgagcgca tcccataagc aaatcctccg agtccacacg tttcctgtcc tactaatcca
    15121 tgtttaagtg gaatcttttc gtccttttct cgcatctcca atcctccaac acgaatttgt
    15181 gagaaaacaa aatcgcatcc tgtaaaagca agctttggat catccgttgc acgaatgcga
    15241 atatttgaaa aacctttttt ttcagcataa atttaacaat caagtacata tccatatttc
    15301 tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt tcattgttca
    15361 aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata gtgataatct
    15421 gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa ttctgccata
    15481 acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg tttaatgatc
    15541 ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc cactacctct
    15601 acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc tccaaacgct
    15661 tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa ctctgtttct
    15721 tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt ctgaatgttt
    15781 ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa aattccgatt
    15841 ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc aacaatacat
    15901 gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc tgctaaaccg
    15961 gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact aaattcaaca
    16021 ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat tcctttgacc
    16081 atctctttat tttctttata agctgcttta tagatagcta gacatatagc tggtatacca
    16141 aacatcatta ctacaaaaaa acctgataaa aacagtccag cctgaggatc tccgttgata
    16201 aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct tcctaaatcg
    16261 taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa acgattcaaa
    16321 aacataaata tccccacacc taatgccccc atatcaacga gcagttttgc aaaattatca
    16381 atcccaattt ggatgagcgg ccagataaag cccaaaaaaa tagctgcgat tgtttgtaga
    16441 atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac tactggtaat
    16501 ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat aattccacca
    16561 aaaatcccca tattcacttc tgggtccatg atttctaagc cttttttcaa ggtagcaatc
    16621 gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa accgattgca
    16681 actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc tgcaccaatt
    16741 actgggatgt tcagcatatc atcagctgat aaacgcatga tcaatcccgc taatggcatc
    16801 gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt aacattcatt
    16861 tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag gatcattttt
    16921 cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgagtac gaggatacac
    16981 aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca tgacttcgat
    17041 cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca cactcgtatt
    17101 gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct caaaataatc
    17161 gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat catatttttt
    17221 tgctaatgta acaactacct cctggttttc atccaaagta tgagtatgat gatgactgtc
    17281 taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat tccattcctg
    17341 atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg atctgaactc
    17401 tccgctttcg ataagagtat cgacagtttt gagaagtggt ttgccacacg tcaatgttaa
    17461 atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcgt gctcgaaacc
    17521 cggcatattt gccatcaatg tagttgatgt caaaattcct cgctgataag catccataat
    17581 cccataattc acaccatggc tatagccaaa atcatccgaa ttaaaaatca cttttcccat
    17641 ttcattctcc ttcttttttc tactaaaata ggcgcaacca aataatcata gtccatttac
    17701 tatgtgtcat ttggttgcgc ctatagatag ttacgccctt attttaatag attcgtgcta
    17761 gatgaattgc caaatagatg atttcatttt cttgaatggc aagttgaaat tgctgttcga
    17821 tgatatcttt aatctttagt gctgtacaat acgctttgct atgtttaaat gtttcagtaa
    17881 aaaaaccaat attttctact ggcgtttctt cctgataaat caagcgttta accaggaatt
    17941 tgatatgaac cattaagcga tgataagtca gtgattcttt atcataaacg tttgaatagg
    18001 atttttctag atgggacaaa atcgtggtcg tcatttctac tatttttaag ctctttaaac
    18061 tattaggctc tcctagctca gcattaatga tatgcatagt gatgaatcct acttcatttg
    18121 accctaactc ggtttgatat cgatgattga ttcgctcgac cacttctatt gctatatcat
    18181 attcatttgg ataaaggaat ctcatttctg gcaacataat tgctgtgaca tctctatctt
    18241 ctctttttcg ttgaatagca aaataaatat gatctgtcaa tgtaatatag atatttgaat
    18301 ctaatggaga ggagatccta gctgttatca gttcaatcac ttcttccgca aaatccataa
    18361 attcgattgg aatctgcgag actatctcac tgaatcgttt gatcttttct ttagaatcta
    18421 atacaaataa tttgtcagca tcctcaacat caaatggctt actcacttta gcagaaaagc
    18481 caatcccttt ccccatcgca attttttcta ttccatcgtc atcgatcaat acagcattat
    18541 gattcagctt tttcatcaca tacaccgtta attcacctcc actatatgat aaaacaaaac
    18601 aacttgcaga ctccttcata catatttttg tctccaaaca atttttaaag acaaaaaacg
    18661 acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa tagtagcacc ctacataatt
    18721 tacaaaaata gtttaacaca taataaaagc gttatcaata tcttttttac tcgttttatg
    18781 ataatacttg tatcgaattg atttggaggt aattacataa aaacaaaaaa aatatagcaa
    18841 ctctctataa gaaagttgct atattgataa ttataccggc ggccggggtc gaaccggcac
    18901 gtcctcaacg gacactggat tttgagtcca gcgcgtctgc caattccgcc acgccggcaa
    18961 atttaaaaat aataactggg gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc
    19021 cttgccttac cgcttggcta taccccaaga ataaagggcg aatgatggga atcgaaccca
    19081 cgaatgccgg agccacaatc cggtgcgtta accacttcgc cacattcgcc atcataaaag
    19141 atgttattta atttctcaat aaaaaactaa gatgaagaca tcttagtcaa taccggcggc
    19201 cggggtcgaa ccggcacgcc ctcaacgggc actggatttt gagtccagcg cgtctgccaa
    19261 ttccgccacg ccggcaagtt gatttattag tactaaggcg gtaaccggat ttgaaccggt
    19321 gatgaaggtt ttgcagacct ctgccttacc acttggctat accgccatta tactattatc
    19381 aatctacaaa ataaagaata aattatagaa actggggtag ctggattcga accaacgcat
    19441 gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa aaagggcgaa
    19501 tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac cacttcgcca
    19561 cattcgccat ggcaggggca gcaggaattg aacccacact aacggttttg gagaccgctg
    19621 ttctaccttt aaactatgcc cctataaaat ggaggagagt ggattcgaac cactgaaccc
    19681 taaggaacgg atttacagtc cgtcgcgttt agccacttcg ctactcctcc atggtggcgc
    19741 gggacagaat cgaactgccg acacacggag cttcaatccg ttgctctacc aactgagcta
    19801 ccgcgccata ttttaaaatt attaattgaa taacaagaac gacggttccg acgggaatcg
    19861 aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg gaaccagttc
    19921 attatggagg ttaacgggat cgaaccgctg accctctgct tgtaaggcag atgctctccc
    19981 agctgagcta aacctccaac attcaattaa aatgacccgt acgggattcg aacccgtgtt
    20041 accgccgtga aagggcggtg tcttaaccgc ttgaccaacg ggccaggtaa atttgctacg
    20101 gagagtaagg gattcgaacc cttgagacag tttgcaccat ctacatgatt tccaatcatg
    20161 ctccttcggc ctctcggaca actctccaga gtgaaagaag ctcaatactc tttctcaaaa
    20221 tgag
//
LOCUS       DBGZHO010000052        20051 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.055, whole genome shotgun sequence.
ACCESSION   DBGZHO010000052 DBGZHO010000000
VERSION     DBGZHO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.055"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..517)
                     /locus_tag="ACN3HL_002064"
     CDS             complement(<1..517)
                     /locus_tag="ACN3HL_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHC8006901.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
     gene            complement(793..1587)
                     /locus_tag="ACN3HL_002065"
                     /note="aph(3')-IIIa"
     CDS             complement(793..1587)
                     /locus_tag="ACN3HL_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HHC8006902.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(1680..2222)
                     /gene="sat4"
                     /locus_tag="ACN3HL_002066"
     CDS             complement(1680..2222)
                     /gene="sat4"
                     /locus_tag="ACN3HL_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HHC8006903.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            complement(2219..3127)
                     /locus_tag="ACN3HL_002067"
     CDS             complement(2219..3127)
                     /locus_tag="ACN3HL_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HHC8006904.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            complement(3160..3894)
                     /locus_tag="ACN3HL_002068"
     CDS             complement(3160..3894)
                     /locus_tag="ACN3HL_002068"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8006905.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            complement(3875..4744)
                     /locus_tag="ACN3HL_002069"
     CDS             complement(3875..4744)
                     /locus_tag="ACN3HL_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HHC8006906.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            complement(4847..5092)
                     /locus_tag="ACN3HL_002070"
     CDS             complement(4847..5092)
                     /locus_tag="ACN3HL_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHC8006907.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            complement(5128..5793)
                     /locus_tag="ACN3HL_002071"
                     /pseudo
     CDS             complement(5128..5793)
                     /locus_tag="ACN3HL_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            complement(5956..6216)
                     /locus_tag="ACN3HL_002072"
                     /pseudo
     CDS             complement(5956..6216)
                     /locus_tag="ACN3HL_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            complement(6386..7123)
                     /gene="erm(B)"
                     /locus_tag="ACN3HL_002073"
     CDS             complement(6386..7123)
                     /gene="erm(B)"
                     /locus_tag="ACN3HL_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HHC8006908.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(7248..7331)
                     /locus_tag="ACN3HL_002074"
     CDS             complement(7248..7331)
                     /locus_tag="ACN3HL_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HHC8006909.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            7477..8157
                     /locus_tag="ACN3HL_002075"
     CDS             7477..8157
                     /locus_tag="ACN3HL_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HHC8006910.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
     gene            complement(8773..9813)
                     /locus_tag="ACN3HL_002076"
     CDS             complement(8773..9813)
                     /locus_tag="ACN3HL_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HHC8006911.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(10162..10488)
                     /locus_tag="ACN3HL_002077"
     CDS             complement(10162..10488)
                     /locus_tag="ACN3HL_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006912.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(10475..11263)
                     /locus_tag="ACN3HL_002078"
     CDS             complement(10475..11263)
                     /locus_tag="ACN3HL_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8006913.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(11631..11921)
                     /locus_tag="ACN3HL_002079"
     CDS             complement(11631..11921)
                     /locus_tag="ACN3HL_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HHC8006914.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(12057..12236)
                     /locus_tag="ACN3HL_002080"
     CDS             complement(12057..12236)
                     /locus_tag="ACN3HL_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006915.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(12233..12583)
                     /locus_tag="ACN3HL_002081"
     CDS             complement(12233..12583)
                     /locus_tag="ACN3HL_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006916.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(12576..13901)
                     /locus_tag="ACN3HL_002082"
     CDS             complement(12576..13901)
                     /locus_tag="ACN3HL_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HHC8006917.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            14351..14965
                     /locus_tag="ACN3HL_002083"
     CDS             14351..14965
                     /locus_tag="ACN3HL_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8006918.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(15130..15372)
                     /locus_tag="ACN3HL_002084"
                     /pseudo
     CDS             complement(15130..15372)
                     /locus_tag="ACN3HL_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15576..16895)
                     /locus_tag="ACN3HL_002085"
     CDS             complement(15576..16895)
                     /locus_tag="ACN3HL_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HHC8006919.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(17029..17637)
                     /locus_tag="ACN3HL_002086"
     CDS             complement(17029..17637)
                     /locus_tag="ACN3HL_002086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006920.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSLNNSYF"
     gene            complement(18275..18532)
                     /locus_tag="ACN3HL_002087"
     CDS             complement(18275..18532)
                     /locus_tag="ACN3HL_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HHC8006921.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(18525..18794)
                     /locus_tag="ACN3HL_002088"
     CDS             complement(18525..18794)
                     /locus_tag="ACN3HL_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HHC8006922.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(18925..19104)
                     /locus_tag="ACN3HL_002089"
     CDS             complement(18925..19104)
                     /locus_tag="ACN3HL_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006923.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            19202..19438
                     /locus_tag="ACN3HL_002090"
     CDS             19202..19438
                     /locus_tag="ACN3HL_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006924.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(19485..>20051)
                     /locus_tag="ACN3HL_002091"
     CDS             complement(19485..>20051)
                     /locus_tag="ACN3HL_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006925.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         6025 a         3853 c         3068 g         7105 t
ORIGIN      
        1 gctctatcat tctgctttcc ggttcttgcc ctcctgatgc aggatattga attgatatta
       61 cccttttatt gcagattgca gtctgaattg ctgcaataac gttatccgcc aatgtatttt
      121 tctgtccaga tgtgctgtac acgttaatac tgttctccaa ctcctgtgca tagttttttt
      181 caccatgctt caaaatagat ttgattttat acatagctga atcaaaatcc tttataaatg
      241 attcatctcc atggcaattt aaaaatttcc ctgctgtaat caatgcaccc acttccgccg
      301 ctgtaaacat taccggcgga agtaggaagc cctctacaag aaaatatcct tttccggcct
      361 cagatccaat tggtattccg gcttcttcaa gtgtccggat atctctgtaa actgtcctta
      421 agcttatatt aaatcgctgt gcaatttctt tggcaggaat tatttttttt gattgcagct
      481 gaataagaat agaggttact ctgttaatcc tgttcaaatt ttattcctcc tctgtgactt
      541 ccataaaaag tatatcctat gcgttcttaa gctagctgct gttagtgctt ctcattgcac
      601 cctggttata aaagccatac tcacaaacct cttcaccaaa actctttaca tctctaatat
      661 agaactctat ctagcgaact tttagaaaag atataaaaca tcagagtatg gacagttgcg
      721 gatgtacttc agaaaagatt agatgtctaa aaagcttgta gttaaagctt tttagacatc
      781 taaatctagg tactaaaaca attcatccag taaaatataa tattttattt tctcccaatc
      841 aggcttgatc cccagtaagt caaaaaatag ctcgacatac tgttcttccc cgatatcctc
      901 cctgatcgac cggacgcaga aggcaatgtc ataccacttg tccgccctgc cgcttctccc
      961 aagatcaata aagccactta ctttgccatc tttcacaaag atgttgctgt ctcccaggtc
     1021 gccgtgggaa aagacaagtt cctcttcggg cttttccgtc tttaaaaaat catacagctc
     1081 gcgcggatct ttaaatggag tgtcttcttc ccagttttcg caatccacat cggccagatc
     1141 gttattcagt aagtaatcca attcggctaa tcggctgtct aagctattcg tatagggaca
     1201 atccgatatg tcgatggagt gaaagagcct gatgcactcc gcatacagct cgataatctt
     1261 ttcagggctt tgttcatctt catactcttc cgagcaaagg acgccatcgg cctcactcat
     1321 gagcagattg ctccagccat catgccgttc aaagtgcagg acctttggaa caggcagctt
     1381 tccttccagc catagcatca tgtccttttc ccgttccaca tcataggtgg tccctttata
     1441 ccggctgtcc gtcattttta aatataggtt ttcattttct cccaccagct tatatacctt
     1501 agcaggagac attccttccg tatcttttac gcagcggtat ttttcgatca gttttttcaa
     1561 ttccggtgat attctcattt tagccattta ttatttcctt cctcttttct acagtattta
     1621 aagatacccc aagaagctaa ttataacaag acgaactcca attcactgtt ccttgcattc
     1681 taaaacctta aataccagaa aacagctttt tcaaagttgt tttcaaagtt ggcgtataac
     1741 atagtatcga cggagccgat tttgaaacca caattatgat agaatttaca agctataagg
     1801 ttattgtcct gggtttcaag cattagtcca tgcaagtttt tatgctttgc ccattctata
     1861 gatatattga taagcgcgct gcctatgcct tgccccctga aatccttaca tacggcgata
     1921 tcttctatat aagcgtaccg gttccaattt tttcgcagtt taacttttcc gacgcattta
     1981 tcgtcttggt agtaaagata tattatctta tcagtattgt caatatattc aaggcaatct
     2041 gcctcctcat cctcttcatc ctcttcgtct tggtagcttt ttaaatatgg cgcttcatag
     2101 agtaattctg taaaggtcca attctcgttt tcatacctcg gtataatctt acctatcacc
     2161 tcaaatggtt cgctgggttt atcgatatct ttcaggtgcc ctgctttcat ttctgtaatc
     2221 actgttcccg cctctcttct atatcagcgg catatgtgct atccaggcag ccggttttac
     2281 cagtgtattt tttatacatg tccctggtat attttgttat attcctatca tactccggat
     2341 aggcataatg aagcctttcc gccacctcac cggataccgc cctgaacaat tgatggcata
     2401 gaaataatgc ttcccatatg ttttcatagg aatccatccg gtaggtggac aaaagtttct
     2461 cccacaaatc ctcggatata tacctttcaa taaacttata gttcttgcct acacttaatt
     2521 taaagcctgt ttcgatgccg accttccatg atatcattct cagcagctca tggcgaacaa
     2581 tctgattaaa atgatcaata gcaaataaaa tttccttacg gcacaatcct ttaataacat
     2641 aaggtgttac attccaaaat tcattgcagc aatcatcata ctcccttgcg cttggctttc
     2701 ttacatgata atctatatca gtcggaacta tgtccctttt aattctacaa tctttatcaa
     2761 ttagaacctt tattaattta tcgcccttta ggtaattatc taactcttcc aagggcaata
     2821 aggtaagatc aattttattg taatcatcaa atagcataag ataggaaaat cccttttctt
     2881 caggtgggaa taattccata tcctccggct tttgcatcat tattatattc ccaaattgat
     2941 taagccagtc atcattagat ataaacggtt ctatatcact tacaaaatat gtaatatcat
     3001 aatcctgaaa ttcatcttta ggtatattaa tatttgcgcg tgacccctca agggtcacaa
     3061 ttcgaatacg ttcatcctgt tctgctaaag aaagtactaa atccatcatt tctttttctg
     3121 atctcattta catactcctc gtttattttt tctatattat tacatcttct tttttgccga
     3181 tacaatcagc atcattgggc gtcgcatttc atccgccatc cccggaatat ccatcatgtt
     3241 ctctggcggc tgtggctcca caatctgatt tattataaaa ctatttgaaa gcagtgtatt
     3301 tagatatgtg gtcagtgttc tatgatattt tgtaaccttt tcttccaaaa acatagctgt
     3361 ccgtttgccc tcataataat aattgtccac cgggaaatgc agtatttctc ctttttcgtt
     3421 ataataccag tcttgtgttc catgagcagt aaaaacagga tgttcaactg taaaaactaa
     3481 attgccacca gccttcagca tcctatatat cttttttatt aaattctcat agtctgctac
     3541 ataatgaaac gcaagcgaac ttagtattac atcaaagctc tcctctggga aatccacatc
     3601 ttctatggca cagcattcat attcaatctg tggaaaatgg gtttttcctt ttgctacttc
     3661 gagcatttta tgagaaatat caacacctac tacagaggaa gcaccgtttt ccatcgcata
     3721 tatacagtgc catccatagc cgcatcctaa atcaagcaca cgcttaccct taaaatcagg
     3781 tagcatcttt ttcaaagtct cccattctcc cgcaccagcc agtcctttct gcgagcgact
     3841 catttgactg tatttttgaa aaaatatatt atcatcatat ttgttttctt tcatctgaac
     3901 tctcctcgtt taaaaagtta tttatctccg atacaatttc attcacttca ttataaagct
     3961 tctcggtcat gtcgtagcat tcaaaaagtg agataccgag tacttcaaaa atatgattta
     4021 ccttctcggt atatttttca ggtttatgtt caaaagtttc aagcagtttt atagctttct
     4081 tttcgttgat acaataagca ttattacatg caaataacac ttgatttaaa catgaaacta
     4141 tacgaaaaac atgacccgca atataatatt tatcgtctgt tcccgaattt gcttttacaa
     4201 acattaaaga gaaccctgct tcaaacataa aaaagttaac taaacttttc tgcaaagcat
     4261 tgggataagt ttctgcctgt ttttttaatt cgcataagct ttcattctta gcatatagta
     4321 ttttgctaat cgctaattct cctcgataca ttgcactaat ataaccatgg ggatgcccag
     4381 tctgataatt ggcagtaaca attccgtgct ctgtatcttt cattatttgt tccacacgtt
     4441 taatatcacg taaaattaaa tccacatgat acccgtttat gactaaccat ccgccgccat
     4501 taatccaatc accccatgct ccgggaggta caacaaggtt atttctatgc tcatcatcca
     4561 gctttgtagc gaattgatta atagtattta tgtcaaatga ttctgaattg taatagatgc
     4621 cgatatctat atccgaatcc tctgtatggg tgccccttgc acgtgaacca cctaaaacaa
     4681 taccttctat ataagacaga gaggataatt tctctgctac tgatttaata atattatcta
     4741 ccatcaagca tgctcctttt atcgattcac tgctgtaaaa attccaagcc aaatcttttg
     4801 cttctactca acatatttat aattttttta atttcacaaa agatagttaa aacttatcaa
     4861 ttgtcttttt atacctctgc tgattagatg aagtcttttc aatagccttt aaattaccat
     4921 tcattttgct aacatggttt aaaaataacg ttccaagcag aagtcgatcc tttctgggta
     4981 tcctattccc cacatatccc ttgaataaat ctttaacaag aaaaacttcg ccatcattta
     5041 gattttcagt ttctctaata gcttcttcca atagctcatt tacatcaatc atgttgtcca
     5101 ctccttatta ataatgggtc agcccccttc tactgtttcg gtttggtcaa tcgcttcaat
     5161 taattgattt tccttttctt ccaaagattg acgaatcctt tcaatctctt ctatagaaag
     5221 ttcatccttt aaatcatcta ttaactcagg taagattttt gtttccacca tttgttggta
     5281 gttttcaagg gctttttgat caaggctatc cttatacttt aaaatacttt ttttccaaac
     5341 gaaagagtat ttattcgcat ccgcttcaat ttttgtacca tcaatgtata gagcactgcc
     5401 actgattaag ccactttgaa ccagtagctc acgaaattga acaaatgaat gatctagaat
     5461 atcgttcata atcggatgaa cgcgaaaacg attaatagta cgaaagttag ggaattgctc
     5521 ttgagataag tagcgcatcc gaatactatc tatcagcata ttttgtattt ggcggcccga
     5581 ataaacccct tgaatatagg cacaaagaat aatggaaagt agcatacgag gatgatattg
     5641 gggtctaccc atagattgat aataaggaag aaagacttca tcgggaatag agtcaacaaa
     5701 ctgcacaatg gcatgagcaa aatcattttc ttctaattta atttcaagat ctataggcaa
     5761 acaaagttgg tttatggtat aattttgata catgataaag cacctctctc aaatggatta
     5821 atcacctata ttatagcaga gtgtgcttta tttttgtatt cactttcaaa agataaatag
     5881 aggtctttcc actactatct aaatggaaag acctctattt ttcatatagg agctactttt
     5941 gggtcagccc catgtttatt ttgaaaaaga gataaaatca atatatccct tttccccaat
     6001 ttttacaacg gcattgtagg gctttttctc tttgtttttg attcctttta ccagggtttc
     6061 ttttccctcc agtaattctt ttacattcgt tttggttagt tttttctttc taaaatgttc
     6121 agctaaagta aacttacatt caggataatt tgaacaacca taaaacgatt tttttaatac
     6181 aatattgttg ccacacttag gacattttcc tacaaggggt cccgagcgct tagtgggaat
     6241 ttgtacccct tatcgataca aattccccgt aggcgctagg gacctcttta gcttcttgga
     6301 agctgtcagt agtatatcta ataatttatc tccattccct ttagtaacgt gtaactttcc
     6361 aaatttaaaa aagcgactca tagaattatt tcctcccgtt aaataataga taactattaa
     6421 aaatagacaa tacttgctca taagtaacgg tacttaaatt gtttactttg gcgtgtttca
     6481 ttgcttgatg aaactgattt ttagtaaaca gttgacgata ttctcgattg acccattttg
     6541 aaacaaagta cgtatatagc ttccaatatt tatctggaac atctgtggta tggcgggtaa
     6601 gttttattaa gacactgttt acttttggtt taggatgaaa gcattccgct ggcagcttaa
     6661 gcaattgctg aatcgagact tgagtgtgca agagcaaccc tagtgttcgg tgaatatcca
     6721 aggtacgctt gtagaatcct tcttcaacaa tcagatagat gtcagacgca tggctttcaa
     6781 aaaccacttt tttaataatt tgtgtgctta aatggtaagg aatactccca acaattttat
     6841 acctctgttt gttagggaat tgaaactgta gaatatcttg gtgaattaaa gtgacacgaa
     6901 tgttcagttt taatttttct gacgataagt tgaatagatg actgtctaat tcaatagacg
     6961 ttacctgttt acttatttta gccagtttcg tcgttaaatg ccctttacct gttccaattt
     7021 cgtaaacggt atcggtttct tttaaattca attgttttat tatttggttg agtacttttt
     7081 cactcgttaa aaagttttga gaatatttta tatttttgtt catgtaatca ctcctgaagt
     7141 tattacatct gtaaataaat acagaagtta aacgatttgt ttgtaatttt agttatctgt
     7201 ttaaaaagtc ataagattag tcactggtag gaattaatct aacgtattta tttatctgcg
     7261 taatcactgt ttttagtctg tttcaaaaca gtagatgttt tatctacatt acgcatttgg
     7321 aataccaaca tgacgaatcc ctccttctta attacaaatt tttagcatct aatttaactt
     7381 caattcctat tatacacaaa atggttctgt tgcaaagttt taaatctact atcaaataag
     7441 gtagaataat agaaaaagat agcaggagga atgacgatga atcattttaa aggaaagcaa
     7501 tttcagcagg atgtgattat tgtagccgtg ggctactatc ttcgttataa ccttagctat
     7561 cgtgaagttc aagaaatctt atatgatcgt ggcattaacg tttctcatac gacgatttat
     7621 cgttgggtgc aagaatatgg caaactactc tatcaaattt ggaaaaagaa aaataaaaaa
     7681 tccttttatt catggaaaat ggatgaaacg tacatcaaaa ttaaaggaaa atggcattat
     7741 ttgtatcgag ccatcggtgc agatggttta accttggata tttggttacg taaaaaacgg
     7801 gacacacaag cagcctatgc ttttcttaag cggttagtga agcagtttga tgaaccgaag
     7861 gttgtagtca cagataaagc cccctctatt acaagtgcct ttaagaaact aaaagaatac
     7921 ggcttttatc aagggacaga acatcgtacc attaaatacc tgaataattt gattgaacaa
     7981 gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa gtttacgcac tgcctctacc
     8041 acgattaaag gcatggaagc cattcgagga ttatataaga aaacccgaaa agaaggcact
     8101 ctcttcgggt tttcggtctg tactgaaatc aaggtattat tgggaatccc agcttaaatc
     8161 atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac cgtccgttgc
     8221 gggtaatacc gtaacactga agggcacgca ttaaggcgtc atcttaatgc tttcctgtag
     8281 gacactgacg gagattacca gtctcccgag ccttacaggg gcctttcttt tttttgtatt
     8341 ttcaattatc acaatttatc gtccaaaagt gcagaacgaa aatcaattca tcacaagcat
     8401 atcagacaat taaatttaaa acaactaaaa atatacaaaa aagtgtaatt gaatattagc
     8461 agcactgcct gaaaagaagt aatatcaggc ttttcagctt ggggaaataa gtgaattacc
     8521 tctcttcatg aattattata actcaaaaaa gcacatatgc aaacactagt tccctatttt
     8581 tttgaatgaa aaataactaa aatatctaac gattatgact ttaaaaccta cgtttgtgat
     8641 tgttttcata aacttttaat ctaaaaactc cggaataata gctatttatt tgtaacattt
     8701 gtaataaaat taaaatcata aaaaagttct aatttaaaat tgatcatttt tatagtgatc
     8761 gctttttatc aactactcta gccaattttc cgtactaact gttggtaatt cgttaaatgt
     8821 ttctctttgt tcgtttgcaa gctttgccgc aatagctttt tcgacaaacc aattttttac
     8881 ataaacgaaa attagattct gcaaattgtt tactttttca gttttttgtt tttgataagc
     8941 tttcagcaaa gtcatatata atcctttgtc agcatcaatt ccataagatt ccagttcttc
     9001 ataaacaaca actgtttgct ctaattcttc agcttttttc tttgcattat gaatagtttg
     9061 gacggttttt tgagcgtctt cgtaagtact agaaaatgtt tttatcaagt ttaatacatt
     9121 ttctggtaca aatgtattta tactgtcctc tttcatgatg tcgacgaagt tatctagtaa
     9181 aacttgattt tgtaactgat cagtttcagt gtctattatg tgtctattag tgtctataga
     9241 attagaatag aatagattgt ctgcgatttt cgcaattacg gttgagtcct tgatatgact
     9301 ggattttgcc gtatttgcga ttttcgcaat tacggtggta tcattgattt ctcgcggttt
     9361 tgccgtattt gcgattttcg caattacggt ggtatcagta ttgtcttcct cttccatgat
     9421 tttaaagacg tcttgattcg ttacttctgg cttgcctaag tacaataaat taggcatgga
     9481 ttcaatctta ccgtcacgtt tatttactct tcctctcttc tgtttcagaa gacctgcttt
     9541 ttctaattcc tttttgattt tagatacttt accttcgcgg cattgtaaca atttcattaa
     9601 ttcttcaact gtgaatatga aaaatatatt atcatcagaa tctacccagt tatttttgac
     9661 tgaataatca aatcgatctt taagtagcat ataagcaatt tttgcatcat ttgatagatc
     9721 catgtatttt tcgttagtaa aaaatacctt aggcatttga taatattttt cacgataaat
     9781 ttcttttgat ttgtaataat taaaatcatt catagccaat cctctttctg taggatagcg
     9841 ttttgttcaa aactatgtta caatgaatta aacaaatata tctatccact atatattttt
     9901 ctactgctga taagtcgcca aactttgtta aagcagtagt ctttttttat ctttttttag
     9961 tttaccttaa aaaataaatt aaagcaaacc gctctatttc aaggtttaag ctcatagtaa
    10021 ctatatcacg atattacaat aatattatat cacgatatcg taatattaca atatgaagat
    10081 aagcgactta tcagctttga tactactgat ttttataaaa aaaatatcac gatattatga
    10141 tatcgtgata ttgaatgtaa attaaatttt attttgtttc tttgctagtt tatatccttc
    10201 aatcaagtat tcttcaggta tggactttaa tagcgcatct tctataacgt ctggtttact
    10261 tttgtctgat tcagcaatag tcgtccaata tttgagtgct gacattagaa ttggatttat
    10321 acgaatgcta tctgctgttc ttacactact tccttgatct tttatgactt tacttatatt
    10381 tttcttggtt aattcgattt cttctacttc ttttgattta aaattctttt tatttttatt
    10441 tcctagtaat ctacttactg cagcttgact gcgattatct tctgccatca aaatcaccaa
    10501 cttcttttaa atattcttct gtaaatgctt tatagtcatc ttcagctgtt gagggtttat
    10561 taaaattgat tagatctgat ccagcagctt gcgcttcgtc aacggttatt gtcctacgaa
    10621 tataagtttt gaaaattttt gcaccaatga ctctagaaat ttcggttgct gcagacgtca
    10681 tttctttaga aatgttataa cgcttattat acttagtaaa tagaactcct cgtacttcaa
    10741 gcttgtcgtt cgtatattct tttaccgttt caatagtttc acttaacttt attagtcctt
    10801 ttaatgagaa atacgcagct tcaactggaa tgataatttc atcagaaaca gtaaatgcgt
    10861 tgactgtaag cattcctaaa cttggtggac aatcaattat aatataatca tagttgtcct
    10921 tgattggttg aagtactctt ttaagcctgt gttcacttcc tacttgagta aattccctct
    10981 ctgcagaaga aagggctatg tcggctggca aaacatcaat tcctttatag tccagaatag
    11041 catctgtaat gtcagcctcc ccttttaata cttcataaat tgtaggttgg tttgttccat
    11101 ctatatcgaa acctacatta tctgtagcat ttccctgagg atcaatgtcc actaaaagta
    11161 catttttacc gtaaacaaat ttcaaacatg ctgctaaatt aacgctagtc gtagttttag
    11221 aaactccacc tttttgattg gctactgaca atattcttgc cattaaaata tcccccattc
    11281 atcttatatt ataatataat tatatcataa tattgtgata ttgcaatatc gtatatgcat
    11341 tatattgtaa tattgtgtga ttattttgtt ttaaagatat atatcggttc ggatataaag
    11401 attattcata tgttattcga aattaaaata atcacttttt attactttaa aattttttat
    11461 taatgataag aaatatgttt tgcgagcagc aactagaata atttaaacat tactaaactg
    11521 tctatattgt tactaataat tcccttctta tagtgcattt tcttagaaaa aaacaatatt
    11581 acgatatcat gatattaaga tatcgtaata ttatacaatt gtgattgata ttatatatgt
    11641 ttttttattt ttttatcatg tttaatcttg aaggaatcat attctttttc taaagacagg
    11701 agcttttcat aaacatcaga catgtttaaa ctagaggcca ggcttaaatc ataaacgaat
    11761 gaagcaggta atgattttat tctacgttgt cgggttatcc agcttgcaac cgttccttgt
    11821 gggtaggcat ataactcaca aaattgttct acagtgattc ctaaattctt gataatgtaa
    11881 acattgatcg ggtgcgagta aacaaatgta ttgatagaca tggtgcgtaa gcctactttc
    11941 ttttattatt gcgtttgcaa taatagttta acacacgcat tattctagta tctactccta
    12001 tttgtaaaaa caaaaaagga ttcatagaga taactctata gaatccgtaa aataccttat
    12061 atatataacg ggaagatata aaacctaaaa ttatgataac ctgctgcagc ttctacatag
    12121 aaagagaagc gctcaacacc aacctcattt atcaaacgtt ggccataacc ccaaatctct
    12181 tctgatagct gatcaaaggt tatatacttt agctcatatt gctggataat gttcattcta
    12241 atcgactcca tttattatcc tggtaaaatt cgatatgacg tatttcgtcg tagtgaattt
    12301 tgtcttttcc aacgtagatc cccagctcat cactacctaa gatcttgcca atgatatctt
    12361 ctggatagta tccttcagcg tttcgttctt ctttttgaat agatactgat ctatttttta
    12421 tgactgcagc gttcaatact tccgcaatct cttcagtcgt catttgttct tttgctaaat
    12481 tttgactggt tcgttgttca ttgtcggcat caatttcttc agtatgatca gataaataaa
    12541 accctgccca ctttaaacgt ccacgatcat tgtaatcaat catttttaat tcccccattt
    12601 ccgcccgcat gaccaccaac aagtgtgctt ctagtaatgc ttctagcgcc ttctaacatt
    12661 gaagaagcat gtacaatcga cgtaaaacca tatttttgcc gaatcttgtc aataatttta
    12721 tctaaatttt cttcgtcaat ttgcttttgt ggatcactaa ataaatccag ctgaagcgaa
    12781 tcggtgtaca caagcttgct ataggttatt ccaacatgcc ttacttcttg tccttcataa
    12841 tacttatcaa acaagaaaag acaataattc tgcaattcct ttgtattatc tgtgataggg
    12901 atcttcatct ggtgtgaaaa ccctggtctc gtttctaaga tcgacgtgcc aatgtgtaaa
    12961 tggacacaac ctgttttaca gttatgctgc ctaatgcgta tcgctacttg ttccgccatt
    13021 tcttttacca ccagctcgat ttcatttctt ctagtataat ctcgtggtaa cacttgtgaa
    13081 tttccatatg atttttcctt tgtcggttct ggtgggattg ctatatctgt tcgatcgatc
    13141 ccattagcat ggaagtacag ctgtaagcca atcacaccta gtctattctt aatcgtataa
    13201 ggattccagt tagcaagatc tctaatgctc ataatcccca tctgattgag tctttttttc
    13261 attcgagagc caattcccca aaagtccgtc atttcaggaa tattccatac tttttcagga
    13321 acgttttcgt acgtccattc cgcaacaaat ccttcattat gctttgcttc gttgtctaag
    13381 gctagtttag ccaaaagggg attatctccg acacctactg tagcaatcaa tcctagctct
    13441 tctttaatat tctcctggat catttgagcc agcttctttc tccgttgact tcgtgttcct
    13501 tcagtcgtaa aaagattcag tgatcgggtc acttttaaga ttgattcatc gatcgagtaa
    13561 atcagtagat cttcatcagc cacatatctt ctgaaaatat tatttacctg catatttcgc
    13621 ttgatatata ggttcatacg tggtggaaca acgtgtagtg ttttaggaaa tggttgtggt
    13681 aagtcacgtg gtctactcac atttgtaata ccataccgct tttttgcttc aggagaagaa
    13741 gctaatatca atcctgaacc agtattatca gctcgactca taacaacaag ttctgttgtt
    13801 aatggatcta aatttctttc tatacattcg acacttgcgt aaaagctttt catatcgatt
    13861 aaaaagtaat catttactgg ctcttttgaa taatccatca taaataacac tccattcttt
    13921 cacattatac aaacatatgt tcgatattgt aaagaagaaa tagctaaata cataaaaaaa
    13981 gaagcatagg tatgctatca ccctgcttct tcttttgatt tgtatgatca atttattcta
    14041 tcactttact aattaatttg aaaatctaat aaaaactctc actctaaaag agtgagagac
    14101 tgcaaattag agtacggact tttttggagt tccgttcttt aatattaaca aatgaataaa
    14161 atccttacaa catttgagaa taagttatca gtagacactt acaaaaaatt ctcatactat
    14221 ttcctccatc attagttttt gtctatataa ggtataccct aaatagacac tggtataaca
    14281 ttgaaaaata tggcttcctc gtgtatgatt agggtgtatt ttaaatagtt gcagaaagta
    14341 ggtaaaagtt ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg
    14401 ccagattgaa gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg
    14461 cgcaacgatt actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga
    14521 tatttttatt gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc
    14581 agtcaattac ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc
    14641 tgaagcaatt ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt
    14701 ggccatgatc gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa
    14761 gatcgcaaaa gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa
    14821 agatccccaa cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc
    14881 gattgctaag attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa
    14941 agacagcatg gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta
    15001 atttcctaca tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata
    15061 aaattccaac aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac
    15121 ttatttacgt taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc
    15181 cttattatct tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact
    15241 aattcctata gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat
    15301 ttgagattta tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata
    15361 cataaagcta tccctgaata attcatagct ttaattcttt ggcacatttt attgaaatat
    15421 gtatcactaa tatccctatc aactgatttt gactaaaaag ttacttcaaa cattcactgt
    15481 tcaaaaatat tgaggaataa attttgggtg taaggcattt tgagcatact tctccctgga
    15541 taacttccca gtaaaaaaat cgttagattg ttggattaga tccattgact ggctcgcctc
    15601 aggcgagcaa agaccctgta gaattcattc tgatacacat gataactaga taatttgaga
    15661 tagactcgtc tacccgtttg gactaatttc ccagcaactt tcagaaactt caatcgaata
    15721 gaatgaatgg tcattccctt ttggacttct tcaaagccaa tcgttcttaa gaagttgact
    15781 aagttgtaag ctatcaagct gagcatcatt cggacatgat tctccaaaaa gcgaggactg
    15841 tctgttttgt caaagtaaaa gccagctttc gcttctttaa tgaagttctc cattgtgcca
    15901 cgtttggcat agatagaaaa gatggtatca ggagaaacat tttctgatag attcgtcacg
    15961 ataaattcat gtcgaaagag tagttcgccc gcttcacgtg ttgagcgtat acacacgcga
    16021 cgactttgtg accaggattg tgcttgataa gtggtcgaga agtactgaac ttctcgttct
    16081 tcccactttt gattatcgcc ataaagtact gatttctcag ctatttgacc tagtctacga
    16141 ttattcttca gtcgaataac ataatgactc ttttttgatt cacacgaatc atacacacca
    16201 ggtgtagcga acccgctgtc tccacgaacc aagatgtcag tgtttggtag agagtgatta
    16261 tagtgctcta ataaaggtgt gagaaactcc tttacgcctt ttgatgtata ttgatttcct
    16321 gaacgtagtt cagcttttaa gaagtcacca gtcaatccgt caaaagctac caatggatgg
    16381 taaccatagg tttggtagtg tgtattataa ttcgtttgtt cttggtgacc aaatgtatct
    16441 gaatgggtcg aatctaaatc aatgattaat tccgtatcat tacggatgag gcgtgcttta
    16501 tcgataagtt cttggttcaa agcttgaagt tcatggatat tctcctcaga tagtcgatct
    16561 aaaaatcggg aaagtgaaga ttgagaagcg agttctttcc tatctaaaac agctttaaac
    16621 acaggatctt gtctcaggag attagctgca gaatcagctg agtaaccagc aattaattgc
    16681 ataatgaact gctcaagtat ggataagttg tcatgagtaa aatacgctcg ttcgtcttca
    16741 atgtgaatgt gttgcttagc cagttcagaa aaaccaaaga tgttcatcag ctctttcact
    16801 aggacgagac ccgaatcact cgataattga ccacctgtat gagaaatagt gatatttgaa
    16861 ttgaatttta cttggttttt gtgtaagcta gtcatgaaaa gaactccttt cttttggttg
    16921 gtttagtcac tttaaccata gcagaaaggg gttctttttt catcacttaa cgggtgaaga
    16981 tgaaaaagta attgtaagct gccgtgaggc agtttcacat ggttttaatt aaaagtatga
    17041 attattcagg ctatcattaa ttttataaaa aaaattaaat gtttttagca ctgccatata
    17101 acattcaaaa cattcttcta tagttggttt acttccttga ggagaatgaa ccaatttatt
    17161 acgtttttct atgaaatttt taatttcctt tcttatttct ttcggaaact caatattaaa
    17221 gtacccttta aacatgctcc ctaataattt gtctacaggg ggagattgta aattctcaaa
    17281 tattagagtt aaatcaggtt tctcttgttg ataaaattcc tttaccccta tttcacaggc
    17341 tgtaattatc gaaataaacc tatctctagt atttgatata tttttacttc ttttaaggag
    17401 tataagagaa aaggggatac tttcgtgtcc atgcatgtaa ttaactaatt gttgagcttc
    17461 agaagttata tctctaatta tatagttaac ggaattagga agtgtcttta actctaatga
    17521 aatttctatc caattactat cttctaatct gtatatgctc gaagtataat ttgattcgtc
    17581 agcaagcatc gctacatccc aaacactgat cataaaatct tttaaacgtt caatcatttc
    17641 agcaatattg ctaaaatcag ctaatttttc tttagaataa aaaaaaacat ttatatcaga
    17701 atcaataaat tctatttttt tattactata tcgtcatcat tatcttgacc atttatgttt
    17761 attgttccct gagtggggag tacttctttc aaattcaagt taaatttata ttccattact
    17821 tctcctccaa tatataaaaa ttacttaact gtatccaaat ttaatatgta aataaatcat
    17881 taatttttag ctaaattcta tgagaagttt atttttgttg tttttgctaa ttaactaaaa
    17941 ctagtacaaa aaatttaaaa tagattatta aacctattgc ttattctatt cagtcatata
    18001 tataagcgtc atcctttagt aactaacatc ccacactaca atagtattat aacatatcta
    18061 ttcaacttca aattgttgaa atttaagcca tttatattta cttttcctca actttagaaa
    18121 tgattttact aaccttatat ccgtaatacg cgtaacaaac acattcatta ataacaatca
    18181 acactaagct atattagctt tttaaatgac tagggtaaat aaaataagga tcaaaaactt
    18241 ttaagtttct gaccctttcc ttacttccga ttggttaata gtgatctttt gcagaataaa
    18301 taaatatcgt ttcattttca actctatata tcagtctatg ttcatctgta attcttctgg
    18361 accattttcc agataaatca tgctttaatg gctcaggttt tcctaatcca gcaaaggggg
    18421 aacgatcgat atcttttatt aacttgttaa tcttttttat attgcttttg tttccttgct
    18481 catgccaata aagataatca tcccaagcat catcagacca agccttaatc atcagattca
    18541 acctcgatta agtcatgtgt tttaaatgca cctttggaga attgttcatc tcctcgacga
    18601 attttttcca tgacgtaatt attagaaagt gttctcaacg tttcttgcat agaatcataa
    18661 tctctttttg ataatacaac aactgtatct tctacatctt tacttgttac aataagtgtt
    18721 tcagcatcct cattaacttg tttcatataa ctacgtaaat tttggcggaa atttgaataa
    18781 gctactgctt ccattccttt caccccttat ttatttctat aaaacaattg tacattatat
    18841 tgtacaatta agcaaatgat taatattcta acttcttata attaaaagtg ctatcacttt
    18901 tagtttttag gataaaaagt gacgtcactt tttgagtgct ggtacctcaa atcctgcttt
    18961 ttcttgggca atcaataaat ctaacgcaat acacataatc ctggattcac ttttgccgta
    19021 cttctgcttt agttgctgca attctttttg tctcttttca tccaacgtaa cgggtaaccg
    19081 tttatttcct attgcaattg gcattagtac tctctccttt catcgaaata accctatgaa
    19141 aaatatggct gcaatcatct tgaatagtag actcacaagg gctaatacaa agcgccaaaa
    19201 gatcaaacaa aataccagta ttgccaaaaa tactacgaag tttaaatgca cagctgcagc
    19261 atggcgcata agtatttcgc caacaaatag gactaacaat agaggaatga ttttattcat
    19321 atggatctcc ttctttctct taggttatcg ggtgttgccc gcttatttcg caccacctaa
    19381 gcggcggggg cggttggagc gattggtgcg aaataagaac cattccctta gttactaggt
    19441 tttttgtcct tatttcacac attctcactt ttcggtataa atgattattg cctttttttc
    19501 ctttcaaatc gttgatatgg cattcgttta cggtcaagtt cattttggat ttcttctgta
    19561 tcgtcgtaag tataggtgtc taaaaaatca gttaaagtcg tgtaccagtc gtcgcctggg
    19621 ttatctactt cttctacata ttccctcaaa aatgcttcgg gtacagcgag ttcataatcc
    19681 attcccatta acacgataga ttccgttcca cacgtcaaaa atctagtaaa tacaaggtaa
    19741 taatcgtcta tcgtcgcatc tttgctgttt agctcttcca tttcttcttc cattaattcc
    19801 atgctctcaa aaattgaata atattctgat tctgagtaat agtgtttcct gcaaatcgtg
    19861 tagctgacaa agttttcgac cagctcactc ctttctaggt aaacattcat gatgtatttt
    19921 tctgtttcta gtcgtagaag ctccgttcct ttttttaccg tttcaggacg acgtttatac
    19981 acgtctaaac gattatggct gactgtgacc ttcgtttgac tcgtttcact ttccaaatac
    20041 aattgttctt c
//
LOCUS       DBGZHO010000053        18894 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.056, whole genome shotgun sequence.
ACCESSION   DBGZHO010000053 DBGZHO010000000
VERSION     DBGZHO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.056"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(20..250)
                     /locus_tag="ACN3HL_002092"
     CDS             complement(20..250)
                     /locus_tag="ACN3HL_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006926.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(686..1252)
                     /locus_tag="ACN3HL_002093"
     CDS             complement(686..1252)
                     /locus_tag="ACN3HL_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8006927.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1252..2208)
                     /locus_tag="ACN3HL_002094"
     CDS             complement(1252..2208)
                     /locus_tag="ACN3HL_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HHC8006928.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2208..2864)
                     /locus_tag="ACN3HL_002095"
     CDS             complement(2208..2864)
                     /locus_tag="ACN3HL_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HHC8006929.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3234..5252
                     /locus_tag="ACN3HL_002096"
     CDS             3234..5252
                     /locus_tag="ACN3HL_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HHC8006930.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5322..5528
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5679..8093
                     /gene="leuS"
                     /locus_tag="ACN3HL_002097"
     CDS             5679..8093
                     /gene="leuS"
                     /locus_tag="ACN3HL_002097"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HHC8006931.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8441..9994
                     /locus_tag="ACN3HL_002098"
     CDS             8441..9994
                     /locus_tag="ACN3HL_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HHC8006932.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10375..12159)
                     /locus_tag="ACN3HL_002099"
     CDS             complement(10375..12159)
                     /locus_tag="ACN3HL_002099"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006933.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12174..13895)
                     /locus_tag="ACN3HL_002100"
     CDS             complement(12174..13895)
                     /locus_tag="ACN3HL_002100"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006934.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13995..14756
                     /locus_tag="ACN3HL_002101"
     CDS             13995..14756
                     /locus_tag="ACN3HL_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HHC8006935.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15723..15991
                     /locus_tag="ACN3HL_002102"
                     /pseudo
     CDS             15723..15991
                     /locus_tag="ACN3HL_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16663..>18894
                     /locus_tag="ACN3HL_002103"
     CDS             16663..>18894
                     /locus_tag="ACN3HL_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HHC8006936.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3352 c         3786 g         5551 t
ORIGIN      
        1 tcattaaaaa gcataaccat tactccgatc tgtttttaaa attagtttct acctctaata
       61 tatatcgagt ttttattttg ccttcagaga atactgtttc tttttttgca gttacaggtt
      121 gtttattttc ggaaaaagct aatatagcta agattgaaac atccatctgg aatttatctt
      181 ttttactgct ttgatcataa aagtctgcat attcatcact gatatttttt ctaataaatt
      241 cttccatcat aaaaatcacc tcaaaacgat tatacgaact tacgttcttg ttgtaaagcg
      301 atatttgagg ggcaaaaaag gggcataatt tgactgatat taagttagct attgatatat
      361 gaatgacata caaaaatata aaatctttta aaaatgctta tatatcaatg tttttgccat
      421 tcttttatat atctgttata tgtcaaaaaa atgtgttcaa tttcaatttg tatttgaata
      481 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaatc aaaaacagct
      541 tctcatgttt ttgatttggt tggacttatt accgcagata taagcttttg agcaccgtga
      601 ataaagaggt tatgaaatca acgctctaac ctgagtatta gagaaaaaaa cgcaaaacat
      661 atcatttatg ttttgcgttt tttatttatc tttttttctc aatacaatat aaaataggcg
      721 gctggttctt ttggttgata aaccgataat tcagcacatt atatgtttcc tgtggcagtt
      781 tggaacaaaa agaatcaacc atatccagtt ctttttctcc accttcatga ccatagtaga
      841 cgacaaggat caatcgtccg cgaggcacaa gtcgtttcaa tatttcttcc atagctgtgc
      901 gtgtagtctc tggcatagtg atgattgctt tatcactttt tgggagatac cctagattga
      961 aaatccctgc tttgagattt tgttgttcag ctatcacttc tcctaacgtt tcgtggcctt
     1021 gtagaaacaa tgagacacgt tcttctaact gacgctgttc tagcctttca cgagtagcat
     1081 cgattgcttg ttgctggata tcaaaactat agacatgacc agtttttccg atgtgttctg
     1141 ctagaaaaac cgtatcgtgg ccattgccca tcgttgcatc tacgacgtga tcccctggtt
     1201 gcaagatttc ttgcagtaat gtatggctga aatgcaaagc agtttgcaac atcagacgct
     1261 cacctttttc cgtacatcat attttccttg gaagctatct ctgcgaagaa gttcttcatc
     1321 aattgcattc aagacttccc attttttcaa gctccacatt ggtccaatca aggaatccca
     1381 cggcgcatcc cctgtcaaac gatggatgat gatctctttt ggtatcattt ccagctggtc
     1441 gcaaatgaca ttgacatagt caggacggct cattaattga aggcgacctt catgatagtc
     1501 ccgcaacatt ctcgttttgc gcatcagatg catcaaatgg agcttgattc cttggatatc
     1561 tgaatctaaa atggtgcgtc tgacattttc tttcatcatt tctaaacttt cgcctggtaa
     1621 tccgttgatc aaatgcgtac aaacacggat attatgtttg cgtaatttag ccacgccatc
     1681 taaataagtt tgataatcat gtgctcggtt gatcagtttt gaagtttctt caaaagttgt
     1741 ttgcaatcca agttctaccc ataaatacat ccgctcgttc agttcagcaa ggtaatcaac
     1801 tacttcatct ggcagacaat ccggtcgtgt accgactgat aatcctacga cacctggtaa
     1861 attgactact tgctcaaatc gttctttgat tatttcaact ggcgcatggg tgtttgtaaa
     1921 attttggaaa taaacgatgt attgttggac atgaggccat ttttgatgca tcatgtcgat
     1981 ttctttctgg aattggattg gaagagggtc ttcaggtgca acgatcatgt ctcccgaacc
     2041 agatacactg caaaaagtac aaccgccatg ggcaacagtc ccatctcgat tcggacagtc
     2101 aaatcctcca tcgatcggca ccttgaaaat tttcccgcca aactcatttc gtaaagcgta
     2161 attccaagaa tgatatcttt tatttccttc tgaataagga aaagtcatta aaagtccttc
     2221 tttctgtaag agttatctat ttgttttctt ttttctctat acactggata agtcaggcac
     2281 agccaagaaa gactgagtaa gtagccgccg atgatatcag taggaaaatg aacgcccaga
     2341 taaatgcggc ttatcccgac acttactata ataaacatca tcagcaattg aagcaatgtg
     2401 cgtaaggttc ttttttgaac aaaagctgga agcagaaata gtaaagaacc gtaaagaatc
     2461 atactgcctg ctgcatgtcc actagggaaa ctgtaacttg tttcaactac taagtgcgcc
     2521 aatgaaggac gctctcgcat gaaaaatagt ttgatcaccg ggttgatgat tccagcaatt
     2581 acaataaatc cagaaacgaa ccaaaatgtt tctgcccttt ttttcttata ccacatccat
     2641 aaagccgcac aagcaaataa aatgatgacg gtaagaggat taccgaattt agtcataaag
     2701 agttggtagc tgttcagatc aggataagaa gctctgacaa tgcctgtaaa ccactgatcg
     2761 aaaccagaaa gccacgacag atggaacttt acgatccagc ccaaaatgaa aaacaggaca
     2821 agaaagaagc taccagccac ctgaaatgat gttttatatt tcatacaatt cctcctttga
     2881 agcaatgact tattatagca tttttggtcc agcgaaaaaa acggtaaaga gataaaacca
     2941 atgtatgatt cctctttgaa taaccaatat tcttataaaa aaaataactg taatcggaaa
     3001 gacatttttt ggtaatgcaa atgaaatgtt agggaaataa aatcagtgtt tttcgaaatc
     3061 cttttaaaca agaacgtaga cgtaggaaga acttgaaaat gaacagaagt tgttcattac
     3121 ggtaaattac aatatgatta caaaaaacaa caaagctctt aaataacttt taataaatat
     3181 taagagaagt tataattatt aataatagat aaattgaagt tggaggatag aagatggaaa
     3241 acattgcaag aaaagaacgg agacgtttag aacagaccaa acgttttcga aaagcaaaac
     3301 gaggggcagc aatcgtggga actgcgatgg taggctgttc tgtcgctgcc ccattagtac
     3361 agccggttcc tgttcaagcg gatgaaacac ctgttcagtt cggcgcaaga atcaatacag
     3421 cggcatttat cacagaaatt gctacttatg ctcaaccaat cgctcaagcc aacgatctat
     3481 atgcatcagt gatgatcgca caagcagttg tagaaagcgg ttggggcagt agtgcgttat
     3541 ctcaagcacc ttattataat ctttttggga taaaaggcag ctatcaagga caaaccgtct
     3601 acatggatac gcttgaattt ttaaataatc aatgggtaaa taaaaaggag cctttccgac
     3661 aatatccttc ttttgctgaa tctttcaatg acaatgccta tgtacttaga aatacttcat
     3721 ttggcaacgg ttattactat gccggtactt ggaagagcaa cacgaaatcc tatacagatg
     3781 cgacagcttg tttgacaggg cgttatgcga ctgatcctgg ttacgcaggc aaattaaata
     3841 atatcatcgc aacttacgga ttgacccaat atgatacacc agctagcgga aacgcaggcg
     3901 gtggagcgac tacaggtggc aataatactg gaagtgcagg tagtactggc ggttcaagca
     3961 attctggtaa tacaaactca ggttcagcaa cttcgaccac ttatactgtc caatctggtg
     4021 attctgtttg gggaatctca aataaattcg gtatcacaat ggatcaattg atccaatgga
     4081 acaacatcca aaacaatttc atttatccag gacaaaaact gacaatcaaa ggtagccagg
     4141 aaaatggctc ttcgacgaat aattccggta acaataccaa ctcttcagga aatgctggta
     4201 catcaaacgg aggacaaaca actggtgcga aatacactgt tcaatctggt gattctgttt
     4261 ggaagatctc aaatgatcac ggaattacga tggctcaatt gattgaatgg aacaatatca
     4321 agaacaattt cgtttatcca ggacaacagc taatcgtatc aaatggcggt tcttctaatg
     4381 ctggagcaaa tactggctca aatactggga atacaagtgg ctctagttcg tccagctcaa
     4441 gttcttctaa tacagcttca ggaacgaaat atacagttaa agccggagac tctgtttgga
     4501 gcgtctcaaa taaatacgga attacgatgg ctcagctaat ccaatggaac aatatccaaa
     4561 ataactttat ctacccagga caacaactga ctgtttcaaa cagtggatca acaaacagca
     4621 cgtcaggtaa tacaggttcg tcaaccaata caaataacag cagttcagtt aatactggca
     4681 gcagttcgtc tcaaggcact tataccgtga aagcaggtga atctgtttgg agcgtggcaa
     4741 ataaaaacgg catcacgatg gatcagttaa tcgaatggaa taatatcaaa aacaacttca
     4801 tttatccagg acagcaattg atcgttaaag gtggaacttc ggcaaataca aatacaggtt
     4861 caactacttc tgcagcgaaa ccaaatacac cgaatacgtc tgctacgaca agtacatcat
     4921 ccactggtaa tacgatgtat accgtgaaag cgggcgagtc agtttggagc gtagcgaaca
     4981 aacatcatat cacgatggat cagttaatcg aatggaataa tatcaaaaat aatttcatct
     5041 atccaggaca gcaagtgatt gtgaagaaag gttcatctca atcaacaaac caacaatcag
     5101 ttactggttc gaaaacctat actgtgaaat ctggagaatc tgtttggagt gttgctgaca
     5161 gtcatggaat tacaatggct caactaatcg aatggaacaa tattaagaac aactttattt
     5221 atccaggtca aacgttgatt gtagctaaat aaaatagctg ttcgaagaaa taacgattga
     5281 attccacaaa aatatttgtt actataaggc tacttaaata tgacaacact tgaaaaggaa
     5341 gtagtaaaaa gactgaagtt tcagagagcg catggctggt gagaatgtgc acggatgctt
     5401 ttgaactcgc ctttgagttg cccttgctga atacccgagt aagcaagcgg cggtgacggc
     5461 cgttacaacg ttcgaggcct tttcactaag gtaaaattag gtggtaccgc gtagattacg
     5521 tcctataaaa agagcaatct ttttatagga tttttttatt tcttttgtga agtttgagaa
     5581 aacaaagcaa aaggaaataa aaataaacag attctgccgg ttttttcgtt atatttataa
     5641 tagaaacaag tgttttcaat agaacaggag gacagcaaat gagttacaat cataaagaaa
     5701 ttgagaaaaa atggcaaaaa tactgggcaa aaacgaatac tttcaacacc catgatgatc
     5761 ctgaaaagcc aaaattttac gcactggata tgtttcccta tccatccggt caagggctac
     5821 atgtagggca tcctgaaggt tatacggcaa cggatatcct ttcacgtgtg aaaagaagtc
     5881 aaggatacaa cgtgctgcat ccaatggggt gggatgcatt cggtctgcct gctgaacaat
     5941 atgcgctaga tacaggaaac gatccagctg agtttaccca aaaaaatatc gaaacattcc
     6001 gacgccaaat caattcttta ggatttagtt atgactggaa tcgcgaagtg aatacaactg
     6061 atccggagta ttataaatgg acacaatgga tctttacgaa gctttatgaa aaaggtctag
     6121 cttatgaagc agaagtagcg gtaaactggg tacctgaatt aggaacagtt atttcaaatg
     6181 aagaagtgat cgatgggaaa agtgaacgtg gtggctatga tgtagtcaga aaaccaatgc
     6241 gccaatggat gctgaaaatc actgcttatg ctgatcgctt attggatgat ctagaattag
     6301 ttgattggcc agaaagcatt aaagaaatgc aaagaaattg gatcggtcgt tcagtaggag
     6361 caaatattga atttaaagtg gctggtacgg ataaatccta taccgtattt acgacacgac
     6421 cagatactct attcggtgca acttactcgg ttcttgcacc tgaactagat cttgttagag
     6481 aaattacgac ccctgaacaa aaagctgctg tagaagctta tatcgaagag acagctaaaa
     6541 aatcagatct aaagagaacg gatcttgcaa aagaaaaaac aggagtattt actggtgctt
     6601 atgcaatcaa tccagttaat ggcaaggaaa tcccaatctg gatcgccgat tatgtattat
     6661 cttcatacgg cacaggagcc atcatggctg ttccagcaca tgatgaacgt gactttgaat
     6721 tcgctcaaac tttcggacta gaaattcttc cagttatcga aggtggagat gttgaaaaag
     6781 ctgcttacac agaagatggt acgcacatca actctgaatt tctagacggc atgaacaaac
     6841 aagaagcaat cgataaaatg aatgaatggc tagaagaaaa tggcgtaggg aaaaaagaag
     6901 tcagctatcg cttacgtgac tggctattct cccgtcaacg ttactggggt gaaccaatcc
     6961 caatcatcca ttgggaggac ggaacagtca cagctgtccc agaagaagag ctaccattac
     7021 ggttgcctaa gacaaaaaac atcaagccaa gcggtactgg agaatctcca ttagcaaata
     7081 tcgaggagtg ggtcaatgtc gttgatcctg taacaggtaa aaaaggccgt cgcgaaacga
     7141 atacaatgcc acaatgggca ggaagctcat ggtattacct gcgttatatc gaccctcata
     7201 acaaaaaaga actagcagat tatgaaaagt tgaagcgttg gctaccagtt gacatctaca
     7261 ttggtggagc agaacatgcg gtacttcatt tactatatgc acgattctgg cataaattct
     7321 tatacgatat cggtgttgtt cctacaaaag aaccattcca aaaactatac aatcaaggaa
     7381 tgatcttagg cgaaaacaac gaaaaaatgt caaaatctcg tggtaatgta gtcaatcctg
     7441 atgatgtggt cgaaacttac ggtgcagata cactgcgcat gtacgaaatg ttcatggggc
     7501 cattagatgc ttcgattgct tggagcgaaa atggcttaga aggaagccgt aaattcttgg
     7561 atcgtgtatg gcgtttgatc gttgatgaga acaataaaat gcgtgaccgt atcactacat
     7621 tgaatgatgg caagcttgat aaagtgtatc atcaaacagt gaaaaaagtg acagaagact
     7681 atgaaaatct tcatttcaat acagcaatct cccaattgat ggtctttatc aatgaagcct
     7741 ataaagtgga cgctctgcct tatgaatata tcgaaggatt tgttcaacta ctcgcaccga
     7801 ttgctcctca catgggtgaa gaactatggg caatccttgg aaatgatggt ggtatttctt
     7861 acgcaccatg gccaacatac gatgaagcag cacttgttga agacgaagta gaagttgttt
     7921 tccaagtaaa cggtaaagtt cgtgcgaaaa gcaatgttcc ccgagactta ggaaaagatg
     7981 agctagaaaa agcagcatta gccaatgaaa tagtgcaaga atatattgaa ggcaaaacag
     8041 tcagaaaagt tattgcggta ccaaacaagt tagtcaatat cgttgctaat taattggctc
     8101 tttgtcaata aggactgatg agttgtgcaa aatcaaatct gggccagaat gaacttcatt
     8161 ctgtctcaga ttttttgtta tttcaaattg attaattgat tgatcaaaaa ggttttgatt
     8221 ttcatgttct caaacacgtt caatgtcttt ttcttctgaa tggtcttgta agagatctct
     8281 gtaatcatca aatttttgtc tattaatctt agtatttttt gatgtataaa ctacctgaaa
     8341 ttgagagtac ataccaaatt cataaatttt ttattagtgg gactagtgat tgtatggatt
     8401 ttgacgcata atgaatgaag tatgagaaaa ggagagacaa atggatcaag aactatttat
     8461 tatcgaagta ttatcagcta aacaaaaaat tatcgagaaa gcgaaaaaaa gagcgaaaag
     8521 aataatgttc aagcttttaa gcttagtatt tttctctggt ttgctttttt tcggagctgt
     8581 atcgttccta tatcgccata tgagtgcagt agtccgttca gctgaaggga tgcaaaaatt
     8641 aaataatttg tatcactttt cgtggggagt tggcggaata acaattgttg tgcttattgt
     8701 ttttcttcta cttatttggc tccgttacca tcaattgtcg cgtcatttcg atcaatggct
     8761 tagtcaaaga gcacaacagt ttttacataa taaaccaact tctcaagatg atgactatct
     8821 ttattttgag aagacttcga cgagtcaagc ttttcggata caaaaaagtg attgccagtt
     8881 attgctgaga tcacttgatg atttacctat ctacttaggc gaaagcaaat caaaattcgg
     8941 aatgaacaca ttccatattt ttttactaga aaacgaaccc agatgggaaa aaagccagtc
     9001 ttcgcctggt ggatacctga caactaagat gagtacatta gtcactggtt ttttcctcat
     9061 tcttttagct ggaacaatct attatgggag atacactcag ccaaaaatgt cttctcatat
     9121 aaatgctgct tctcacatga caatgaactc aactaacgat acgcatatac aaaagacaaa
     9181 tgaagggttg ttagctgatc ctaagcaaaa ggtaaatttg acaacacaaa agataaatga
     9241 tctcaaactt gatacagaga cgcactctct ctatatgaca acagatagtg gtgctaattg
     9301 ggtatttgtg ccgattgatt cgcaatggtt gcgttttggc gaatacaccc tgacaacggg
     9361 gctgattcct gaaggttatt ggatggacaa cacatatgat atttccgccg atttctcatg
     9421 gtttatctat tcttctgggg atgatgtacg tctgctgact tcaagagata atggtaaaac
     9481 atggcaaacg tctattatca cccaatcagt tcagccgata cgttatcgaa aagcggtatt
     9541 ttatggcaac gatggtctat ttatctgtac atcagccagt gggatgtctg cagaaacttt
     9601 gtacatttac actactatgg atggcggaat cacttggata aaaagtggaa gtacaatgat
     9661 caatcagcca gtacaaaatg tcagcttcgt tacaacttct ttaggttttg tttcgacacg
     9721 tgaaagtttg ttttatacaa acaacggagg acgctcattc aaagaatcag ttctgtcgat
     9781 tccggaaaac tatcagacag gggggataga tctttttcaa tcaccaaatg aagttactca
     9841 aataagcgcg aatacgttag agacaaaatt ttatttgttg aaaaaaggac caatcgatgc
     9901 agggaaaatg tttgcctgcc tcttccgttc aactgataac ggggaaacat ggcaattcgt
     9961 tcagcaacta tcgcaagtag aacaaggaga ttaaagaaga gagattgtga gcctgacgtt
    10021 cagcaccgag tcacaagaaa caaattcaaa aaacagcttc tcatatttgt tgaatagtgt
    10081 aactcgtgat tcggagttga caagagcaac aagaagcgat tttgaagtat agcttctcgt
    10141 attttacaag atcgtgtctt attgccgata ggttgtctct tgaacaccgt ttattcgtaa
    10201 aaagggattg tgacaagtct tttgtcacta cttaccgaac gaaactgaag gagctatcca
    10261 aaaagtatca ttagtattat tctttgtgtt tctagtggca ccactagtac atttaaaaaa
    10321 gctatcgatc atggactaat catacatgat cgatagcttt ttagataatg tttgttacgc
    10381 tatctgaaat tgactattat aaagactggc ataaagcgtt ggtgattgga gtagttcaga
    10441 atgtgttcct ttttcgacga tatcgccatt cttcattaca aggatcatgt ctgcattttc
    10501 aatcgttgac aaacggtgtg caatcacaaa acttgtccta tcttttgtca cagcttccat
    10561 tgcttgctga atcaatgctt ctgttcgtgt atctacgcta gaagttgctt catctaaaat
    10621 aacgacagga ggattcgcta gaatgactcg agcaattgtc aataattgtt gctgtccttg
    10681 agataacgtg ccgttttcgc tagaaatgat cgtatcatat ccgtctggca gtgttcgaat
    10741 aaagtgatca cattgtgcga tttcagccgc ttcgataatt tgttctcttg tggcatccat
    10801 tttcccgtag gcgatattat cagctaccgt tccttcaaac agccaggtat tttgtaaaac
    10861 catcccaaaa gaacgacgta gttctccacg tgaaagcttg gtaatatcaa gaccgtcgaa
    10921 ttcgatcttt cctttattca gttcataaaa acgcatcagc agattgacta aagtcgtttt
    10981 tcctgcacca gttggaccaa cgatcgctac cgtttgtttt ggctttactg aaaaatcgac
    11041 ttgattcatc aatattttat ctgatgtgta accaaactgt acatttttga aagctatttt
    11101 tcctttcggt tgttctaaaa gtcttgcatc tggaaggtct ggaatttcat ctgtttcatc
    11161 taatatctca aatatcctat cgattgctgc cattgcggat tggatcgagt tgatcacata
    11221 agaagcggta gaaattggtt cagaaatctg attgatgtac tgaagataag cttgtaagaa
    11281 gccgatcgtc acaccacctg atagaacaag catagcaccg aataccgcac ttatgatgaa
    11341 ggcgagttga ttaatgaaac gaatggccgg atagatagca cagttcataa attgagcacg
    11401 tttaaaagcg ttgtattgct ttttatttac ttcgtgtata gcagcttctg catgagcttg
    11461 ctgattgaat gttttgacca ctagattacc agctaagatt tcttccattc gattatttaa
    11521 aacacccagt tcatactgat tctgttcaga aatctgtttg tttttgttcg caatcttagt
    11581 tgtaacaatt gaactgccaa cgatcagcaa taagacgagc aaagtaagct tgctttcgat
    11641 ataaaacagc atcagaccag cagcagctat tgttacgaca gaagtaaaaa attgattgat
    11701 acctgtcaat aacacttgag aaagttgatt gagaccggta gttgtccgac taatgatgtc
    11761 acctacttga tgattgtcaa aaaacgacat cggtaatgtt ttgaattttt ttgtgatttc
    11821 ttttcgcacc ctcaatgtga tcttttcgct taacgctgcc attgtccgtt cctgaataaa
    11881 tgaagtgatg ctgcttaaga ctgaacagcc gatcagcaat aagacaggga acaacaatgc
    11941 ttgtttgata tcactgaaag aaagctgtcc aatacctgtt tttcttattt ctgataagag
    12001 atcatcgatc ccgattccca tgatcaaggg catggctacg actaataggt tcccgaataa
    12061 actgcataga aacaatccgt aaaaatattt atgttcaggt ttgatcattt tccaaaaacg
    12121 tatcaaagca cgcgtgttca acgttttttt cttttccatc gtatcccttc tttctatatt
    12181 ccttgtgatt ttgcaaactc ctgataagtt tggcaattag acagtagttc ttcatgagta
    12241 ccttgtccaa cgatttttcc ttcatctaaa acaatgatgt tatctgcttg ttggattgta
    12301 ctgaggcgtt gagcaacaat cacgagagtt ttctccgaca tgtgtttatg aagggctgct
    12361 cttaatgctg catctgtttt atagtctaaa gcggagaaac tatcatcgaa tacatagatc
    12421 tctgctggtt tgatcaacgc tcgagcaata catatccgct gtttctggcc ccctgaataa
    12481 ttagaaccgc cttgagcaac aaagctgtcc aatccgtcag gaagggtgtc cactagttct
    12541 tctaattgag cgatcttgat cgctttagac aactcttctg ttgaggcata ttcatttccc
    12601 atctgcaagt tgcttaaaat tgtcccgctg aataagaaag ccttctgagg gacataactg
    12661 atgtgggagc ggatctgttc ttgagtcatt tgagtaagag gaataccacc aagggttact
    12721 tttcctatcg tagggtcact aagtctcaag agaagtttcg ccaaactact ttttccagat
    12781 ccggtcccgc caacgatcgc tgttgttttt cctttaggta ttgtgaaatc aatatcttct
    12841 agaactggat cagagatttc agtatattta aatgtgacat gttcaaaagc agctgcattt
    12901 gtctgatcaa aggttggttc agctactgtt ttgatcgtct cttcctcaat ttcgatctct
    12961 gcttgcagta tttcttctat ccgtcgtaat gaggcaaacg atttagggat aatgaccaat
    13021 accatagctg cgatcatcaa gtaagcaagt gtcagcatag agtattcgac tacagcagtc
    13081 acgacaccga tttgtaatgc tccttctgct acaagatttc cgccaaacca caaaatagaa
    13141 gcataaacga ttcccatgag caaaaaagca attggagtga cccaagcaaa tattcggttc
    13201 actttgatca tttgattagc atagtcagca aagctcttat tcgttcgctt ttcttcatat
    13261 gattgattat caaaggcacg gatcatatta atcccagtaa agaattctct caatgtgatg
    13321 gtgatccgat ccatttttgg ctggatactc aaagataaag gtgcccctcg tttcatcagt
    13381 cgataaacaa tccatacata aaaaacaaca gagatcaatg taacccatgt tagtaataga
    13441 gaataacgaa acatcatgag aatggtgaaa acgcaaataa ccggtgctgg taagatcatt
    13501 tggcaaaata aaacaatcat ttgctggaca ttatcgacat cattcgtcat tcttgtcaaa
    13561 agagatccag aactaaaacg actgatatcc ttcattgaca gctgttggaa tttacggaaa
    13621 tatttctccc gcgtttggaa tccaaaccta gcggaagcca atgctgaaaa gtaactagag
    13681 gcaactgcag cgattgttcc tagaaacgct acaagcagca tttcaactcc aatttttttt
    13741 ataactgagg cttcgccact tgctatacct gtgtcgatca gctttgctac taattttggt
    13801 acacctaatg taccggcgat ttctaaacag atcatcacaa aggtaaggag agcgagtcct
    13861 ttgtttttct gtaagaatgt ttttaagata gacatattat tcctcctttt ttcctgatac
    13921 ttttcgattc tataccttca agtaacttga aggtcaatag aaaaaagaat aaactgaaaa
    13981 agaggtgaga aaaaatgaaa aaaatgtata cgattggcca agtatcggaa ctatttgatt
    14041 tgccaaaatc aacgatccgc tattgggatg aacaaggatt aatccgttca agtagacaag
    14101 aagagaatga ttatcgattg tttgatatcg atgatatttt tatgctttat gatatcgttt
    14161 tttatagaaa attagatata ccgatcaaac agatgaagaa tttatatgga aaaacattga
    14221 cggagttata tgagacactt gatgaaacag aaagaagaat ccataaagaa ctggtggtga
    14281 tgaaacaaaa acaaaaagag ataagggagc aaaaaaaaca gttgaaattg atgatcgata
    14341 caaacgagga agaatttcct gtagaagaga tcccttttga ctgtatgatc tcaacggagt
    14401 ttgaagatat tgtggaaatc aaaaaatttc tacctaacta ttcaagcttt gggatgatga
    14461 gtatgccagc ttccagttca cagacgatgt atggattttt tatcgaccct agtgaagtac
    14521 atttatttac tcaagacgtg atttgggaga aaaaagatac ggctgtttat cgtcgattct
    14581 tattgaaatc cgagatgaac catgcggaac gtaataatat tttagaaatc agagaaagaa
    14641 tgtatgaaaa aggatggaaa acaggagaag tgatcggcca gtatctattg acgaatacgg
    14701 atgaaaacaa tatcagaact gaatattatc atgcatggat agaaatgaaa aaataggaaa
    14761 tatgtgttta agataactcg aaaatgatgg ttgttttagt tataaagaaa aattttctgg
    14821 ttcgattacg ggtttaatgt gggggattat tagtcgtgga tagatagaat tttagttttt
    14881 tagaggaaat atgtctttaa aaatggaatg gttgcaattc ttagcgatat atacgatgta
    14941 attgtcctct taaaaaagta tggaaaaata attgtattgg gtgttatgta taattcatgg
    15001 tgaactgaga ctaatgagaa gaaaaattca tattgttatg agtgagattg tatcagatga
    15061 gaatgataaa ttaaataggt gcataaaagc attacactta aaatacattg ttgcttacat
    15121 tattacaata tgttaataag gcaaaaataa atagatggat tgaataaaca tattttttaa
    15181 tcaaatagtc cctactgtga ctttcctcag ctatcggtga tactaccgat agcatttttt
    15241 tgcttataaa ataattataa gtatttagag atttttcttc taacattctt caaacaagaa
    15301 aaatcacaaa ggttattgtt atttttatat attcttttta agaatgattg tttttttata
    15361 gaaattttaa aaaataaaac acgttattga tggatagtta gtttgttatt tggtaatatt
    15421 atagaagttg actggtagtg atttattttt cgtcgtttta taaaaatgtt attttttgga
    15481 aaaattcaca aatatgtaac gaatgttttt ctggaatttg ctgtgttaaa aagcagtatg
    15541 actaatataa atactattgt catttatgca attttttatg gatagtaatt ttagagggga
    15601 atcaatgaag gaagaataga agggaaaaat agttgcaaat acgccagtta gcaaaaatag
    15661 caatacatct tcaagcttta aaattcgaga gaatcatctt ggtagtggaa tcaactacaa
    15721 caaaaggatt aaaccaatta atagatagaa ttaccaatgg aaaaatagaa aaggtagtta
    15781 ttctatacaa aagttgttta attcgcttcg gttatgaact tagtgaaacc ctttgcaata
    15841 tatggtacag aatatagaaa ttattgacat tacagaaaat gatgaagatt taatacagat
    15901 tgtcactatt tgtagatacc ttttacaagg aaaccgagcc aataaagcta agaagatgat
    15961 taaggagttg atggaagacg atacaagtta agaaagtgaa actacgccca aataaagagc
    16021 aaaaagagta attggacgtg gaaaatgcaa gaaatgaacc atcgattcgg tggacagttt
    16081 attagtaatg acggtttgag aacatccatg acgagaatga aggaacatcc taaatgcgtt
    16141 tagttgaacc aagtgccaaa taatatggcc aaataagcga tcagttatcg atgaatccca
    16201 agtattctaa actatatatt cattttgatg ctaagcattg atatattttt ttgggattga
    16261 tgaaggttaa ccaatacagg gactcactga tgaaattcta gagtctgacc ttggtatcaa
    16321 cgatttagtg attgtttcta atggaaaagt ataaaagtat ataagtacat taacaaaata
    16381 actattaggg ttacgctcca gcttgtgcaa ggcactggca ggaggaatcg tgaaatcata
    16441 attatggtta agccacacgg acaactaaaa gtcatacaaa gctatcgaat caatcaacag
    16501 aagacaatcg gcaatcatta gctttgttta cagcttacat tgcaacgctt gagttgaacc
    16561 gaaaatacga gggaggtaac gcagccattt tgagttgggg aatcttttta gaaaattatc
    16621 gggtaccttg ttgtttagtc aaaattataa gggggagtaa tagtgaggaa caaatttcat
    16681 aaactgttaa gtatgtttct agttatgctt attgtgatca atcaatttgg gaacataacg
    16741 gttctagctg agtctttagc agaacagcca gagcgttcgc tgacgatcga agttgatcaa
    16801 gaggaggctg ctttgggtga gcagttccag ttgcgagtca gaggaacacc agacctgcta
    16861 aatgcattgg tcattgataa gagtgaggat ttgattgaag gggaagtgaa gcaactcaat
    16921 gattacgaac gtctgattac ttattcttcc cagcattcag gtaaatacga attgaccgca
    16981 agaagcggtg atattcaatc aaatacggtc tcaatagaaa tcagtgtacc agaagaaagc
    17041 acaagtgagt cttttaatgt accagaagaa agcacaagtg aatcttttaa tataccagaa
    17101 gaaagcttaa gtgaatcttt taatgaagcc agatcatctg agccatctat aacgcaggaa
    17161 tctcagattg aaagacaaga ggagctcttg aattatgaca tcggcatctc tgctgagcgc
    17221 cccactttgc cgagcaggca tacacaaacg ttaaagggat acattcaagg aggcgctggc
    17281 gatattcttg aagaatatgg ggagatggtc gtacgagttc ctagagcatc gattggctta
    17341 attgagttca ttagagtgga ggtcgctgat gattcacctt taaagccact ggcattttac
    17401 caagaaggca cagacgttgt ttttccattt acctttgatt atgaaggatt aaatgaagcc
    17461 gctcagtcgt atacattcag tatcacgttt gaagttgctt tctttcaatc aggcggtact
    17521 gagccaaata atgactttca agtgagtctt acttatgctg agcgagcagc aaacacggaa
    17581 ttttcaatta cgcctattcc ttcatcaaga cccatttttt cgaaattata ctatggctct
    17641 agagaaatcg acagccaagg aaatcttggg aatctgctga ttgacgggca agacgtgacc
    17701 aacagtaata aatttatttt gcaggtaaat tatgaaggat cacgaaaaga cggtgtagtg
    17761 gttaccgatg tactaccgca aggaacaact ttggcaccga atccgactac atggagttcc
    17821 actggaaata gagaacctat ttcaggtggg gttcggatcg cagaagtaac gaatccaggt
    17881 gaagcaaacg ttagaactca ttatgtttcc gaggaatttg tggacaaagt atcttttaat
    17941 aaggaaacga atacacttgt tgtggacttt ggtaatctag cagagggtca atcgtatttt
    18001 attgaatatg ctcttgaagt gaccgatgtc gacttgttca atgaaggaag acaagaggat
    18061 gggttttctc ggaatcgagc gagtatgacc tacaataatc aggtaatgag ccgagactac
    18121 cgcttgagaa tccctgaaag taatcttccg gcaatctctt taagaaaaag tgtggacaaa
    18181 aatgttatca atctcaatga aaatgaacta acgtatactc tgcatgtctc gatgttttct
    18241 ggaacaagaa atacgcttgt tattgaagat gttttggaag aaggcatgga atttgtgtca
    18301 tttctatcag atattccctc tttcattgat gccgaagtca ataatggaat agttcgtttc
    18361 agtgcgaata atacgattgg tggtccgaca agttttaccc tctcttttaa ggtcaatgta
    18421 gaggcgtatg cggtcggcga tcaaatttta aactttgcaa cgcttgtgaa tagtgacaat
    18481 cgattgaata cgagtactgt aagaacaagg aaaatcgatg ggcgtattaa agtaattaaa
    18541 actgatgaga atggccaaag gctggcagga gcaaaatttg aaattttatc aagcgattca
    18601 caagtgatac aagaaggtat aacggcagaa aacggagaat ttttaagtga accgcttcct
    18661 gtaggtagct atcaagtccg agaaacagaa gcaccggaag ggtatctttt agatgcgacg
    18721 gtacatgatg tttttataaa tgaatactcc atagaagaag tgacgttaac cattgaaaac
    18781 atccttgata cgggtggtgt tgaactaatt aaacatgctg aaggcagtgg tgaagtcctt
    18841 caaggagctg tttttgagtt acagaaccga gaaggagaaa cgctacaaac cggt
//
LOCUS       DBGZHO010000054        17208 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.057, whole genome shotgun sequence.
ACCESSION   DBGZHO010000054 DBGZHO010000000
VERSION     DBGZHO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.057"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(170..3319)
                     /locus_tag="ACN3HL_002104"
     CDS             complement(170..3319)
                     /locus_tag="ACN3HL_002104"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HHC8006937.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="ACN3HL_002105"
     CDS             complement(3333..4550)
                     /locus_tag="ACN3HL_002105"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HHC8006938.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..6135)
                     /locus_tag="ACN3HL_002106"
     CDS             complement(4540..6135)
                     /locus_tag="ACN3HL_002106"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HHC8006939.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6260..6532
                     /locus_tag="ACN3HL_002107"
     CDS             6260..6532
                     /locus_tag="ACN3HL_002107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006940.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPA"
     gene            6632..7045
                     /locus_tag="ACN3HL_002108"
     CDS             6632..7045
                     /locus_tag="ACN3HL_002108"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021111.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HHC8006941.1"
                     /translation="MRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAGSVYRAVDF
                     CYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSPIPNWKALI
                     EMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
     gene            7038..7280
                     /locus_tag="ACN3HL_002109"
     CDS             7038..7280
                     /locus_tag="ACN3HL_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006942.1"
                     /translation="MTNNILISIYPRYMEKIINKQKNFEFRNFYLTSDPYNIFWIYET
                     IPTKALKYKLIVKNPITKLKKNQHYFLGDDEFEQLV"
     gene            7688..8113
                     /locus_tag="ACN3HL_002110"
     CDS             7688..8113
                     /locus_tag="ACN3HL_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHC8006943.1"
                     /translation="MHLHRISALAVQIGRYHHSETRAVMEGLEEAIQTTNDCPYRRTF
                     HSDQGWSYQMKAYRNKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCF
                     EELKSAIDSYIYYYNNERIKQKLNWQSPVQFRKTTVTVV"
     gene            complement(8408..9541)
                     /locus_tag="ACN3HL_002111"
     CDS             complement(8408..9541)
                     /locus_tag="ACN3HL_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006944.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(9532..10200)
                     /locus_tag="ACN3HL_002112"
     CDS             complement(9532..10200)
                     /locus_tag="ACN3HL_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8006945.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(10656..11642)
                     /gene="lacD"
                     /locus_tag="ACN3HL_002113"
     CDS             complement(10656..11642)
                     /gene="lacD"
                     /locus_tag="ACN3HL_002113"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HHC8006946.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(11655..12581)
                     /gene="lacC"
                     /locus_tag="ACN3HL_002114"
     CDS             complement(11655..12581)
                     /gene="lacC"
                     /locus_tag="ACN3HL_002114"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HHC8006947.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(12594..13109)
                     /gene="lacB"
                     /locus_tag="ACN3HL_002115"
     CDS             complement(12594..13109)
                     /gene="lacB"
                     /locus_tag="ACN3HL_002115"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HHC8006948.1"
                     /translation="MKIAIGCGHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(13128..13556)
                     /gene="lacA"
                     /locus_tag="ACN3HL_002116"
     CDS             complement(13128..13556)
                     /gene="lacA"
                     /locus_tag="ACN3HL_002116"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HHC8006949.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(13576..14349)
                     /locus_tag="ACN3HL_002117"
     CDS             complement(13576..14349)
                     /locus_tag="ACN3HL_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8006950.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            14514..14993
                     /locus_tag="ACN3HL_002118"
     CDS             14514..14993
                     /locus_tag="ACN3HL_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8006951.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            15050..15352
                     /locus_tag="ACN3HL_002119"
     CDS             15050..15352
                     /locus_tag="ACN3HL_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HHC8006952.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            15374..16831
                     /locus_tag="ACN3HL_002120"
     CDS             15374..16831
                     /locus_tag="ACN3HL_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HHC8006953.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
BASE COUNT         4963 a         3616 c         2942 g         5687 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttcgtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tctactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcttgtt tttttgcata tttcaacgcc gcatctagct
     2161 tttgacgggt tgtaataatc acaacatttg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcgttc ccggaagaaa
     2281 tcccagtatt aaattccgaa gcaaatttcg taaactctgt ggtggtttga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgtccgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtttttcctg aaccagtcgc atgccacaca tatcctgatt
     2461 gatgtttatt tgcagcaata aacaaggctt gaatcgcatg tacttgataa ggatgtaaca
     2521 ccatgaggat tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gagcatccgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atcctttggt aaggcatttg
     2701 caaaataccg agtggtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa cataccttct tctgcatatt ttttgatttg gttaaacgcc tgataaaaac
     2821 tatcttttgc ggttacttgt ttcagctcga tttggacaat cggtaatcca ttgatcagta
     2881 aggtgacgtc aaaacgtcga tcccgtgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataggtagag attcctccac caatgtcttg attagaataa agaatgagcg
     3001 agacagaacc cagttgcgga tcttcccgtt caatcgtgat ccgagccatt ccattttcac
     3061 cttttaacca tttcgcagca tcaaaggggg ttttcgttcg tagtaacaat tctgttttga
     3121 tcgtttcaaa ttctttatcg gtcaaaggaa aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg gcgtaaattg acccaaagat cttcttctga ttttagatcg ggacgatacg
     3241 tccactgatt atgcccttcc cccaatacac ggatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt tatcttccct ccctaaacaa acatcttttg taagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattgtg gcaatcaggt cttcttttga ttcttcatct gaaagtaatt cacgatacaa
     5941 cattgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
     6001 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agtcccaata aataattttt
     6061 atattctgac gcatccattt tactacggag attatctgcc gcactaaata atttttgatt
     6121 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
     6181 tattttagca tactcccttt tagaaaaagc aaaaaaaaaa gaaaaaatct tattcttgat
     6241 aacaagctac gtgacgtata tgcctaacaa aaatagaact tttgaatcaa tcttaaatga
     6301 aggtttaacc acagaaccgg catccattat ttttgatgaa gttatcgatg acgttgaaga
     6361 tagtaagtat cataaaaatt taaaagaact tttttatttt gcactcaaca atggaccaag
     6421 tttgttcact ggtatatcag tacctgatag tgataatcca ttaattatgg caaaaattta
     6481 cttaacaaaa tggtgtaata aatacatcag ggataggaat aacccagcat aaaaaaaacc
     6541 tcttaaaaca tttggcgaaa aagatgctgc tttaactact agagtagcag caaatgctaa
     6601 tattgatgat caaaaagtat tgaatgacta cttgcgtgga cattttttat atatgagcgc
     6661 tgagaacatg aacggaagta ttttagagga atatttagcc gaagtgttag aacctgaagg
     6721 ttggatttgg tgcgccggct ctgtatatcg agctgttgat ttctgttatt taggaacctc
     6781 accaattctt ttacaagtga aaaataaata caatacagaa agcagttcga gttcagctat
     6841 aagagtagga acaacaatta gaaaatggaa tcgtttaaat aagtcgacaa aaatttctgg
     6901 tttggatagc cctatcccca attggaaagc attaatagaa atgactgaag ctagtaagga
     6961 actggcagct aagttaactg aaaatagtta tttagcttat attaatgaaa aatccacacg
     7021 agaattatgg acactcgatg actaacaata tccttattag tatctatcca cgatacatgg
     7081 aaaaaattat aaacaaacaa aaaaactttg aatttagaaa tttctatctt acctcagatc
     7141 cttataatat cttttggatt tacgaaacaa tccccaccaa agctttaaag tataaattga
     7201 ttgtaaaaaa tccaattact aaacttaaga aaaatcaaca ctacttttta ggagacgatg
     7261 agtttgaaca attagtttaa aagggaaaat atgcttctat cattacaagc tcgtttggtg
     7321 taagatgggt ataagtcatt tatgttcact ctccttgtat gctttagcgg gtattacaat
     7381 ttgagtgtaa cataaatggc ttttttattt gtctcgctta attatacaaa cggcgaatta
     7441 taaataactc ataaaaaata ttttgacttt caaaatcact tttgctacca gaagttgagg
     7501 cgaagtgttt taagcatagt tgtaccctag tttgaccgtt aaaaataaat aacgatcgct
     7561 agagtgcaac tatgtttgtt tgccctaccg tcagcgtcgg cttggcctct cacatccatt
     7621 accgtcggga ttatctccgt tacataccct tacaaaatac gccctgtaag cattgcatga
     7681 aaccaccgtg catttgcacc gtatttccgc cctagccgtt caaatcggtc gctaccacca
     7741 ttcagaaaca cgtgcggtaa tggaaggttt ggaggaagct atccagacca ctaacgattg
     7801 tccctatcgt cgtacgtttc actcagatca aggttggtcg tatcaaatga aagcttatag
     7861 aaacaaattg aaggagtaca aaatctttca aagcatgtct cggaaaggga actgcttaga
     7921 taattcactt atggagaatt tttttggctt attaaaacaa gagatttttc acgggaaagt
     7981 ttataactgt ttcgaggaat taaaatcagc catcgatagc tatatctatt actacaataa
     8041 tgaacggata aaacagaaat taaactggca aagtcccgtc caatttcgta aaacaaccgt
     8101 tacggttgtg taaaaatatc attttagagc atgaaaaaaa gagtggattt ctccactcca
     8161 aaaaagtcta acttttgggg gtcactacat ttttgatcct ttttatttga ttaattatat
     8221 ccagctggat aataattttg ggggcaacat ttctatctta ctattatctt cctaaagtag
     8281 tagactttct tattgggaaa aattacaaca aaaaggagtg gcttagttga caactccttt
     8341 ttgtttacaa atcaattgga tatctataaa ttgtattttc taacgaattt tatagacatc
     8401 tgatttgtca aattaagcta gacaatatgt ctttatctat gcagctcaaa aatacttcca
     8461 atggtgttcg ataatttaat gattttcttg gaatatggtt tcttttcgag gcaacggatt
     8521 gaataaaggt ttcatccgtg tccctaaagt ccattgtttt aggtaagcca tcctgcttga
     8581 gcccatgcac tcggtactga tgagaaaaaa ttgatgcctg tttctcctga ggaatgccaa
     8641 ttccctgatc ttttacttca ataatcacgc tacccttttg gtttgaaatg gtgacaatta
     8701 ccagttttcc ttcaccatat ttgattgcat tgtcaactaa attcgaaacc gcccgataaa
     8761 tccaacgatc tcgtccatga atcagggttg gttgatcttc agtaaacgca aacaaaagat
     8821 tcggataatt cattttgtag gcatcacaaa cttccgcaca gatcagtgaa acgtctacga
     8881 cttccgtgct aagatcctct gagttattgg ataatgtcaa aatatcgtca atactgtcgg
     8941 tcatccgatc taaaagcatt aaatttcctt gatcggcatg ttgccgttct atttccagat
     9001 tcgtacgcaa aatagcgatg gcatttttct gctcgtgggt cagataacta tttaatcgtc
     9061 gataatcctc caaatgacca tcgaacttat cctttagctt attaaaagcc gcatttaatg
     9121 cctcgtcctt cacagtattt ttaggaactt gatcaataaa cgttaaatca cgcgtaatcg
     9181 ctaagatttg attactgtaa attttgcgta aaaccaacca aagaataaac gttaataaca
     9241 tgacggcaga acaaataacc agcaccatcg ctggtaaata tttaaatagt tcgtcctggt
     9301 aagctttatc tatcatcgaa atagtcataa attgattgtt ggaagatttc gaagcttcca
     9361 tctgcgtctc tgcttgaacc gtcttaccct cttccataaa ataaacatct tcacctaagg
     9421 tagatgcgat actgattccc tccaaattat ttctcagaaa gaagaaactc actaaaatca
     9481 cgcctgtcac caacagtgaa aaagccagca tcgttaacgt cattttaaaa tttaatagca
     9541 tagctggtac ccctttgctc gaatggtttt taagacctct ttttcagctg cttcagccag
     9601 tttctttttt agacgagcca gatgcactcg cagaaccgac gaaaaaggat caaaatcttc
     9661 atcgtagaca tgttcagaaa tttcctcaga cgaaacaacc gctggatgac gctgagcgat
     9721 gcacagtaag atatcaaatt ccttgggttt caggaccacc tctgtctttt gatagctgac
     9781 ccttcgacct aatggatcaa tcttcaaagc accaattgaa atctgcggca gcgcacgtcc
     9841 atgataacga cgaataaccg cgcgtattcg tgcttttaat tctagtaact caaagggttt
     9901 gactaaataa tcatctgctc caaaatccaa gccttttgct cgttcttcaa tctcatcacg
     9961 tgcagtaata atgataactg gactttcgac ttcttcagca cggagacttt gtaaaacaga
    10021 taatccatct tttttaggca gatttaaatc tagtagtatc ccatcgtatg aattgatgaa
    10081 ggccttctct tctcctgact cgccatcata agctacatct acagaaatat tctcctgctc
    10141 taggcccttt tttacggata aaaccagctc acgattgtcc tcaaccacca gtacacgcat
    10201 gtatattcac tcctcatacg gatttagtaa ttacacttat gctttttagc atagtacacg
    10261 ctcttcttca aagtccacgt tctttttgtg aagatttgaa gaaattcata cattctgtta
    10321 aaaaacacat aattaagaat gattttactg tttgaaaata cctagaatag aaaaagactg
    10381 gaacctttcc tccagtctca ctactttcta tttgcttggt tttcttgtat atacttttca
    10441 aagttcgttg gtttatgacc aataagcctc gttagaatac tgaaaattgc catcaagtca
    10501 ttaagtacca catgtaagaa aatctctcta aagaaaaacc ccttcgtttt aactcactta
    10561 ctattttaga attcgttccc ctaataatgc agcatgattt tacgctttat gtataaaaaa
    10621 agactgcaag caattttgct tcacagtctg atttcttatg atagtgagct tgttaacact
    10681 tccaccggtg tagcagtttc tttcaatacg gcatttaatt cttcaatatt tttacgccct
    10741 tgcgtattca tccactccat cgctgcttct tttccatcaa cgatatagct ttctacacca
    10801 tctgcccaag tcgcacggcc gcaaagtaca ccattgaagg ttgagccggc atttttcgcg
    10861 aagcgcagtg tttcttggaa caactctgct tttacaccgg cgcttaggaa aataaatggc
    10921 aggttagtgg cttcagcctg ttccttgaag aagttagccg cttgtgcctt tgtgtacacg
    10981 acttcgtctg tcccatagcc ttccacataa ttcatattga cgggtacttc cacctttaac
    11041 acatctacgc cataacgtgg atcagaaaat tccttcatca tatcgttgac tttatgaggt
    11101 ttcttaatgg cgtattcttt cgaagtcgca tcagagatgt tcgcgtcata agaaacaagc
    11161 tccaagaaga agggtaagtt ttcagcctga cattctgagc cgattcgttc aataaaggca
    11221 tgtttttgat tattgatttc ttctgcttca tcgacatcat agtaaagtag gaacttacaa
    11281 gcatcggcgc ctgcttcttt taaacgttta actgaccaga tcgataataa atctggtaaa
    11341 cggccgggag ttgacgcatc gtaaccagtt ttttcataag ctaacagcaa gccggcattt
    11401 tttgctctaa cgtcagctgc tggcaagcca tattcgggat ctaataaaat cgatgaggca
    11461 tatttcgtta attgtgaaga aacaatttct ttaaattcaa cgatttctga ttcttctgct
    11521 tcgctgccct tgaattttgt gatcatcttc ttcaaagccc cgcgttgatc aattgctaag
    11581 gccccaatca ctccatcttc attgcatagt tgcttgatat attgacgttt ttcttcgttc
    11641 atttccgtat cctcctacac tttctccact aagatttgat catatagttt ttgataattg
    11701 gctaattgga catagccagt cgtcgcttcc tgagcattca gcattcctaa aacattaccc
    11761 tgttttaaca cggcttcatc cgaaagacct tgttgaatcg cagcggtcaa tccggcaacg
    11821 gtcgcatcac cagagccaac tggattgacg acatcaatct ttggaattgt cacgcaataa
    11881 aaagtctcgt gatgtttggc aaaggctccg tcgcccccca ttgaaaccac tatccattca
    11941 atttcatcaa acatcgaatc tgacaaggcg gcttttaaat ctgataattc tgttgagatt
    12001 tctcgtccta gcagaccagc cagctcttcg gtattgggtt ttattagctt aggctttaca
    12061 ctgcctcgca acacttccct taatgctgta cctgaacaat ctaaaacgac aggctttggc
    12121 tgacaaactt gcagcatttg tcgataaaaa tcagcaggca atccttctgg caagcttcct
    12181 gaaaaagaaa tgatttcggc tttaacagct aatttttcga aatgttgcaa gaacgccctt
    12241 gcttcttgtt cagtaataac aggtccgttt tctaggattt ccgtctgttt tccgtcatgt
    12301 aaaacagcga tgcaattacg tgtctctccg ctgataggta aaaagtcatg agcaatctca
    12361 ttttgagtca ggtccttttt aatctcttca cctaaaaaac cgccgattaa accactagca
    12421 atcacctccg tatctaattg cttcaagata cgtgtcacat ttaggccctt accgccagct
    12481 gttttgcgaa catttcttac tcgattgact gtgtcgagct tgaaggtttc taatggataa
    12541 gaaatatcaa tcgatggatt catcgttatt gttaaaatca tttgtccacc cgcttaatcg
    12601 tggtattcgc cacgatccca tttctcgata aattcatcga agaaatgcgg atcagactgc
    12661 ttgtcactgg ctttttcgac gtgatcgatt ttggcgatca attttttgtt ttcttcagtt
    12721 tcttgataat cggcattgat gaaggcctct aatatgtcac agatcaaaaa ttctcccgta
    12781 atccgagcgc caaagccgat cacattggca tttagttgtt ccttcgcata gatagcagtc
    12841 gtcatatcgc gaaccagcgc actgcggata ccaggtactt tattgacagc gttgttaatc
    12901 ccaacacctg ttccacacaa acaaactcct agatctgctt ctccgctagt cacggcctct
    12961 ccgacttttt ttccgtagat cggataatgg gttctggtaa agtcataggt ccccatatcc
    13021 aacacttcat gtccttttga ttttaagaaa tctgatactg ccatttttgt atctgtgacg
    13081 atgtggccac agccaattgc gattttcatt tcattcatcc ttcctaatta cgccatttta
    13141 tttaacatgt cgacacgtac ttgatgacga ccaccatcat aatttgcttg tagaaattcc
    13201 ttaacaatat tcaacgccaa ctcatcgcca acaatttttg atccaagtgt gatcatccga
    13261 gaattattat gtttacgggt catatacgca ctgcgctcat ccgaaacttc tgctgctacc
    13321 attcctttaa cctttgttgc cgtgataaag ctgccagcgc cgtagccatc aaccgcgatt
    13381 cctaaactac cttcgttttc attcagatca tttgcgatcg ccaaagttga ttccacaaaa
    13441 tcttctgaag ccgtttcact cttatctact actgtaatac cttctttgat caattttttc
    13501 ttgattaatt cctttaattc catgccgtca ctgtctgaac caattactac acgcattttt
    13561 gtttcctcct attttttact gaatgatttt agtgaattgc tgataataac tcttcagctc
    13621 ggctgaaaga gtagaatccg taaataattt gtcgatcttg cgcaaatcat agaaattata
    13681 aaaatcgcta tggtcgaatt tgtttgcatc tgaaaccaaa catttttctg ccgcattatc
    13741 taaaacaatt ttttgcaagg taccttcttc aatactgaaa ttcgaaacct ccgaaccctt
    13801 caatccattc actccgacaa aagccttctt aataccgatt ttttgaacag cttcattggc
    13861 aattgaaccg acaaaggctc cagtcttttc ccgatatagc ccaccgatca aatacagttc
    13921 aaatcttttt atttcactta atagattgaa aaccggcaga ctattggtaa cgattcggag
    13981 agatgacggc ttgatgtatc gtgtcattaa ttcgatcgtt gtacccgatc caagaaaaat
    14041 cgtgtcgtct tcttgattga tatgagctgc cgcattttta gcgatgtatt ccttctcttt
    14101 tgtatgcagc ttcttttttt cagtatgaga aagctcattt gcttctatag aagtcgacat
    14161 ttccagataa tcgatttttt gtgcaccgcc atgaacgcgt aaaagctttt tcttctgcgc
    14221 gagttcctct agatctcggc ggatcgtcat atctgaaaca ttcagtactt cctgaataaa
    14281 tttgactgtt atcgtcccat agcgatcaca catcgctaag atcgaacgct gtcgttctgt
    14341 tttcagcata ttctgtacct ccacgacctt ataataaaac atttacgaac atttttcaac
    14401 acatattgtt cgtttatttt cgtttatgcg ttgacaatga ttttgtaagc ggttatactc
    14461 aacttgtaaa catataaata aacataaacg aactaataaa ggagctgttt tgtgtgaatg
    14521 aattcttttt caaagacact gtctatgttt ctgacaagca gtcgcaggaa gaagtgttcg
    14581 aggaagtcta tcaagatctg ttaaagaaag aattggtaac cgaagatttt ttggagaacc
    14641 ttttagaacg ggagcgtaat tatccgacgg gattagatct ctcacctgtc tctaaaatat
    14701 tgccagatat cgctatccct cataccgaaa gtgagtttgt gcgaaccacc cgtatcattc
    14761 caatcaaagt aaaaaatgaa atccctttct acaacatgat ctcgccaagc gatcagattt
    14821 ccgcttcatt tcttttcatg atcttgaacg aaaatggtga agcacaggct ggcatgttgg
    14881 ctaatatcat ggatttcatt aattctgttg acgaagaaaa actgttttcg tttttcaaat
    14941 tagaggacac agaagcgatt tatcattttt tagaagaaca tttttatata tagaagtctc
    15001 tgcctaaccg caggataaaa aataaactta ttttaagggg agaattatta tgatcaaaat
    15061 tttagcagca tgtggagcag gcgttaattc aagccatcaa atcaaaagcg ctttggaaac
    15121 tgaattgaaa aatcgtggct atcaagtcac ctgtgacgcc gttatgatca aagatatcaa
    15181 tgaagaaatg ctgtctcatt atgacatttt cgcacaaatt gccaacaccg acttgggttt
    15241 tgacattaac atccctgtcg ttgatgcagg tgctattctt tatcgtattc ctgctatggc
    15301 tgagcctgtt taccaaagta tggaaagcgc aatccaatca ttaaacaaat aggactaaag
    15361 aaaggaaaag catatgaata caattattga tattgccaat aaagtattta cccccctaat
    15421 taatttaggt gcggcaccgt taatgaccat cgtattaact gttattgctt tattttttaa
    15481 agtaaaaccg tcacgcgctc ttgaaggcgg gctcaaatta gggatcgccc tgactgggat
    15541 cggagctatt attggaattt taactactgc tttttcagac gctatgacag cttttgttga
    15601 acgcacaggt atttcattaa acattacaga tgtcggttgg gccccactag caaccatcac
    15661 atgggggtcg ccatacacgc tttatttttt actaattatg gtgatcgtca atattgtcat
    15721 gttagcaatg aaaaaaacca acacattaga tgtggatatt ttcgatattt ggcatttagc
    15781 aattgttggt ttgttcgcga tcttctgcgg tgctaatctg tttattgctt ctgcattagt
    15841 tattttcatt ggtgtattaa aaatttggaa ctccgactta atgaaaccaa ccttcaatga
    15901 cttgttaaat gcgccagaca gcaacccgat gaccacgact catatgaact acatgatgaa
    15961 tccgattatt atggttttcg ataaaatttt cgacaaaatc ttcccttggt tggataaata
    16021 tgatttcgat gctgccaaat tgaatagtaa aattggcttc tggggatcaa aattcgcgat
    16081 tggaatttat ttggggattt ttgttggatt actagcagga caaacaccaa cgcaaatttt
    16141 ctcgctagcc tttaccgctg ccgtctgttt ggaattgttc tctttgatag gcgcttggtt
    16201 catcgcagcc gtagaaccgt tatcacaagg gattaccgat tttgccaata aacgactaaa
    16261 aggacgtacc atcaacatag gtttagactg gcctttcata gcaggccgcg ctgaaatctg
    16321 ggctgccgct aacgtattag caccaatcat gttgctagaa gccatcatct taccaggaaa
    16381 taaattattg ccactaggcg gaatcatcgc aatgggtgtt accccagcac tattggtcgt
    16441 aactcgtgga aaattaatcc gtatgatcgt aatcggcgcg atcgaattac cattattctt
    16501 atggtccggc accttgatcg ccccgttcgt tactcaaaca gctaaagcag tcggagcctt
    16561 tccagccggc ttgaacgggt ccgccatgat ctctcataca acgatggaag gcccgattga
    16621 aaaattccta ggttatttag tcggtaatgc ttctcaagga caaatcgaat ttgtgatata
    16681 cgctgcctta gcattaggtg catacctttt aatcttcatt tggtacgctc gtcaaatgaa
    16741 aaaacgcaac gctgcatacg cagctgaaaa agaagagaat gcatctccgg caacggcgca
    16801 taatatgact tatgcagccg aagctaaata agctaaaaac accccgaatg tctttagact
    16861 tcggggtatt attttaccta taaaaaataa atagatgtaa aatccatttc aaaaagcata
    16921 gcccatctct tgccacaccc aataaagaaa ttatcaacgt ttatgctttt tttaactcct
    16981 ttaagcttgc ctttgttggt attcctcaac gattcttttt gtgttcttgt ttgttttgtg
    17041 ctttttgact ttttgttgtt taattgcgaa ttccttgatt tcttttttcc tgaatcgctt
    17101 cgcatcccgc ggttatgcgt gcgatttcat cattgctttt tctgatctaa ctcgtttcat
    17161 gtcaaagagc ttcagctgac ttagtgtcca tggttgtttt gatatccc
//
LOCUS       DBGZHO010000055        17164 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.058, whole genome shotgun sequence.
ACCESSION   DBGZHO010000055 DBGZHO010000000
VERSION     DBGZHO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.058"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(36..845)
                     /locus_tag="ACN3HL_002121"
     CDS             complement(36..845)
                     /locus_tag="ACN3HL_002121"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8006954.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1138..2574
                     /locus_tag="ACN3HL_002122"
     CDS             1138..2574
                     /locus_tag="ACN3HL_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HHC8006955.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2744..3940
                     /locus_tag="ACN3HL_002123"
     CDS             2744..3940
                     /locus_tag="ACN3HL_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HHC8006956.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4002..4187)
                     /locus_tag="ACN3HL_002124"
     CDS             complement(4002..4187)
                     /locus_tag="ACN3HL_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HHC8006957.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4418..7732
                     /gene="dnaE"
                     /locus_tag="ACN3HL_002125"
     CDS             4418..7732
                     /gene="dnaE"
                     /locus_tag="ACN3HL_002125"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HHC8006958.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7900..8862
                     /gene="pfkA"
                     /locus_tag="ACN3HL_002126"
     CDS             7900..8862
                     /gene="pfkA"
                     /locus_tag="ACN3HL_002126"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HHC8006959.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8936..10720
                     /gene="pyk"
                     /locus_tag="ACN3HL_002127"
     CDS             8936..10720
                     /gene="pyk"
                     /locus_tag="ACN3HL_002127"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HHC8006960.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10755..11657)
                     /locus_tag="ACN3HL_002128"
     CDS             complement(10755..11657)
                     /locus_tag="ACN3HL_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HHC8006961.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11843..12412
                     /locus_tag="ACN3HL_002129"
     CDS             11843..12412
                     /locus_tag="ACN3HL_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HHC8006962.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12470..12649
                     /gene="rpmF"
                     /locus_tag="ACN3HL_002130"
     CDS             12470..12649
                     /gene="rpmF"
                     /locus_tag="ACN3HL_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HHC8006963.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12819..14240
                     /gene="gndA"
                     /locus_tag="ACN3HL_002131"
     CDS             12819..14240
                     /gene="gndA"
                     /locus_tag="ACN3HL_002131"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HHC8006964.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14433..15119
                     /locus_tag="ACN3HL_002132"
     CDS             14433..15119
                     /locus_tag="ACN3HL_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8006965.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15116..16621
                     /locus_tag="ACN3HL_002133"
     CDS             15116..16621
                     /locus_tag="ACN3HL_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8006966.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         5552 a         2980 c         3594 g         5038 t
ORIGIN      
        1 gtcacaacct cttttttgtg gaatctaatt ctctattata gtttaagtag tttttccaga
       61 taaacagcta aaccgtcttc ctgattgctc aaaggagtga catcatttgc aatgcctttg
      121 agttggtcag taccgttagc catagctact ccccaacctg cataatccaa caattccaaa
      181 tcattatgct cgtcaccaaa ggcaatgacg tctttttgat cgatagacag gtagttagca
      241 atctcttgca cgccttttgc tttttggatt ccttttgaaa caatctctaa gatggcagta
      301 ggtccacccc atgtccgaac atcgacataa ctgccaaatt gacgtgttaa ttcagcagat
      361 acagctcctg caaaacgttt gtctgttcgg acaagcaaag atgtaggatt tgtcgtcaaa
      421 tttttaggag aaagcaaatt cttctctcct ggacgagaag aagcaaaaat tttttcatca
      481 aagaaatcaa aactgtcaat aaaaaaagta tcacgatttt cagcagcgat aaaatctaaa
      541 tttagctgct ttttttgcga taagatttca aaagcgattt cacgattgat caacgtttct
      601 ctttcaccat cccagtgctg attagggatg tgtactaatg cgccgttaaa attaaccatc
      661 ggtgttgtta attctaattg ttggtaaaac tgatggctca ttcggaatgg gcgtcctgta
      721 gcaatactga catgatgacc ggcattgatt gcttttttta gagtctcttt tgttttagat
      781 gtaatcatcg aatcttgatt gagggtagtt ccgtccagat cgatggcaat taatttttta
      841 ttcaataagg gtccttcctt cctcaactag catttgtttt agtctagcat attttaggta
      901 attaacaaga gcaatcagct attcctaaca aaaactacag ttatggctat ataaatagct
      961 aaacataagc taaacacgaa cgttaagtat tattttcgct ttttttgtta aaaaaacgtt
     1021 gaaaagcgaa tgaaacgtct atataatttg aaattgttcg atggatttgc cctattttac
     1081 ttatttttta ttattatagt tttccatcag aaaaaaattc agggagtgga actttttatg
     1141 gaaaagtttt tcggtttaaa gaaaaacaat acaaatgtat caactgaaat aatggcggga
     1201 gtaacgacat tctttgccat gagttatatc ttattcgtaa atccgacgat tttgtcagca
     1261 tcaggtatgc ccttccaagc agtatttcta gcgacaatca ttgcatcgat tattggtacg
     1321 ctggtaatgg gattgttcgc aaatgtacca tatgctcagg cacctggtat gggattgaac
     1381 gcatttttca cttttacggt cgtttttggg cttggttatt cttggcaaca agccttggca
     1441 atggtgttta tttgcggatt aatcaatatt tttattactg tcacaaatat tcgaaaaatg
     1501 attattcggg cgattcccga aagtcttcaa catgcgattg gtggcgggat cggtattttc
     1561 gttgcgtatg tcggaatcaa aaatgcagga ttcttatctt tttcagcaga ccagtcagct
     1621 atttcgagct ctgtcgttga aggcggaaaa gcgacaaatg ttacgataaa tggtggaatc
     1681 gtccctgcgt tagccaactt tgacaacgct cctatcttat tggctgtgat tggtttggta
     1741 ctgacagcca ttttagttgt aaaaaatgtc cgtggggcta ttcttatcgg tatcgtagcg
     1801 accacagtcc ttggtatttt tatgggtgtt gttgatttaa gttccattga ttggcaaacg
     1861 aattcgttag gtaattcatt taaagaatta ggaacaactt tcggtgcagc atttggttct
     1921 gaaggcatgc aatctttatt cagtgattct tccaagattc ctcaagtatt gatgacgatc
     1981 atcgcattca gtttatctga tactttcgat acgatcggaa catttatcgg tacaggacgc
     2041 cgcacaggta ttttctcaaa agaagacgag atcgcgttgg aagatggtcg tgggttcaaa
     2101 acaaaaatgg ataaagcact atttgccgat gcgatcgcta cttctgtggg ggctatcttt
     2161 ggtacatcga atacaacaac ttatgtcgaa tctgcagctg ggatcggggc cggtggacgt
     2221 actggtttga cttcagtagt agtggcagtg ctattcgcat taagtagttt attctctcca
     2281 ctgatcgcca ttgtaccaaa tcaagcaact gcgccagcat tgattttagt tggagtaatg
     2341 atgatggctt cttttgcaga catcaaatgg ctagatatgg aagaagcttt accggccttc
     2401 tttgcatcga tctttatggg attgtgctat agcatttcct atgggattgc agcaggattt
     2461 attttctata caattgtgaa agtaatcaaa ggaaaataca atcaagtttc tgttgctttg
     2521 tggatcgttg atattttatt cattatcaac ttcatcattc tagcaacaat ttaactaaag
     2581 agaagggatt ggaacagtat ttgttctgat ctctttttgt tttacataaa aagaacgtta
     2641 catataaaat gacctttgcg ggatttttct ctttttactg gcgagatcgt tgcttgttta
     2701 ttcgaaaata ggtatgataa aagagacgaa agagggatga tagatggaga ttaattggag
     2761 aaaaaattta gtgattgcgt ggattggctg ttttttcact ggtgcaagta ttagtttagt
     2821 tatgccattc ataccagttt atgttgagca actaggaaca ccaaaagatc aaatcgaatt
     2881 gttttcggga ctagcaatct ctgtgactgc ttttgcatct gccgtggttg caccaatctg
     2941 gggaaatcta gctgatcgaa aaggccgaaa actcatgatg atccgtgcag cagcagggat
     3001 gacattaaca atgggatctt tggcttttgt accaaacgcg tattggcttt tgatcatgcg
     3061 gttttggaat gggattttgt ctggatatat tccaaatgcc acagcgatga ttgcttcaca
     3121 ggcacctaga gaaaagagcg gatgggcgtt aggaacattg tctaccggag cgattgctgg
     3181 aaatctgatc ggaccttcaa tgggcggtgc actggctcag tggtttggta tggaaaatgt
     3241 attcttgatc acaggggctt tgttgatgat cacaacggta ttgaccattt tcttagtcaa
     3301 agaagatttc catccaatcg agaaaaaaga tctgataagc accaaagaaa ttttttcaaa
     3361 aatggatcat ctctctattt tgatcggtct cttcattacg accttgattt tacagatagg
     3421 aatcactacg atcagcccta ttttgacctt atatattcgt gaattgagcg gaagtacaga
     3481 aaatatcctt tttgtcagcg gcttgattgt ttcgatagct ggtgtttccg ctgtcttttc
     3541 ttcaccgaaa ctaggaaaac taggggataa gattgggaat caaaaagttc taattggagg
     3601 actcatttta tcattttgct gttatttacc tatggcattc gtcactacac cgctccaatt
     3661 aggtatactt cgctttattt taggcttttc aactggcgct ttgatgcctt ctgtcaatac
     3721 actgatcagt aagattacgc ctcaagaagg agtcagccga atctatagct acaatcagat
     3781 gtttagcaac tttggacaag ttttaggtcc catgctagga tcgacagtcg cgcatgctta
     3841 taattacagt gctgttttta ttgtgacaag tttgtttgtt ctgtcaaata ttcttctttc
     3901 tttattcaac tttcgtaaag ttcttcgcag cagattataa tggtggtgag gagtagaaaa
     3961 taaaaaagag cttgagaaat ctcaagctct tggctgtttt tttacgaatg ggcagaggtt
     4021 tcttttcttg gcgcaactgc accaatcaaa aggataatga cacccgcaat gaatgaaatg
     4081 attgttgtca aagtaaaatc atatgttccg cttgttaatg cagcaccaat ataaccgact
     4141 acttgaccta gaacgacagc ccagaataat gtaacgatat atcgcataaa gaacacctct
     4201 tttctatctt aattttacca gattttcttt gaatgtaaag aaacgagacc aaatctcaat
     4261 aaaatttgag ttcttgcgaa agaactcatt cctacagatt acaagcaagc aaatgaagtg
     4321 gaataatcaa cttcagcgcc tgctatctta atgaaagtaa aaggatcaaa ccttttaacg
     4381 ctagtgaatt ttaacgaaaa aaaaggcgga atgcaagatg tttttcccac aactttatac
     4441 aattacttct tattctcttt tacaaagtac gatacgtatt cgagaatatg tacaagaagc
     4501 aaaaaaacaa ggctacactt cattagccat aacggataaa gatgtcttat acggtgcacc
     4561 tgaattctat cgtatttgtg tagaagaagg agtacagcca atcattggat tacatcttag
     4621 ttatacttat gaagaaaaaa attatggctt gcttgcgtac gcaaaagatg aaataggtta
     4681 tcagcagctg atgaaacttt ccagccgaaa aatgatccaa gaaaaattgg aacttgcaga
     4741 aatgacagaa accgaccatc tagcgtttgt tgttccggca aatcattctg tttctgaggc
     4801 tttcaataaa gaggataact ttttcggtca ttggcagttt ttacttgaaa atgtttttac
     4861 tagaaatttt tatatcggct tgacagaaaa cacgcctgat caattgcctg aatggtatca
     4921 gtatgtgata aaagaaaatt attcgctttg tgcattacat cccatcgcta gtttacaaca
     4981 agaagaactt tttgcacttg aagtgatgaa acatatcaaa gagggaagcc aaataccttt
     5041 agaaaattta tctgcatctt taccactaac agcaaatgtc tatcttcttt cagaacaaga
     5101 aatgatcaaa cgattcgaaa aagcgggtct ttcccaagct gtaataggcg cccagcgttt
     5161 agctgaatcg atttcatttg aattccagtt ccatcagaaa ttacttccgc attatccagt
     5221 tcctaatgga aaacaagctg gagaatattt aagagagtta tgctattcgc aagtggaacg
     5281 ccgaatcact gactatacaa aggaatacca agaacgtttg gactacgagt tatctgtcat
     5341 ccatcaaatg ggattcgatg attatttctt gatcgtatgg gatgtaatgg cttttgctca
     5401 tagaaacaaa atcgttaccg gtgcaggtcg tggttctgct gcgggttcat tagtagccta
     5461 tgtgttagaa atcacagatg tggatccatt agaatatgat ttgctgttcg aacgcttttt
     5521 aaaccccgaa cgctttacga tgccagatat cgatttggat attcctgaca atcgacgtga
     5581 agaagtattg aattatgttc gagaaaagta tggacaatat catatggcac aaatcgcaac
     5641 atttggcaca atggcagcaa aaatggttct tagagatgca gctagagtgt ttggtttatc
     5701 gcaaagtgaa gcaaaccgct ggtcaaaagc aatacccaat caattgaaaa tcacattgac
     5761 ccaagcttat aaaacttcgc atcaattagt agaattagtt caggcaagcg aaaaaaacca
     5821 acttttattc aaaactgcag tgattttaga aggattgcca agacatgttt cgactcacgc
     5881 agcaggtgta gttatcagcg ataagaatct acttgaacta gttccgctcc aacgcggttc
     5941 tgatgaagct tttctgaccc agtatacgat gaatgaggta gaagcaatcg gtcttttgaa
     6001 aatggacttt ttaggactac gcaacttatc gattattgat tttactttga aagctgttaa
     6061 gcgagtagaa gggtatgaga tccgattaaa agagatcccg ctaaatgatg caaaaacgct
     6121 gctcttgttt caacgaggcg aaacctcagg agtatttcaa tttgaatctg ctggtatccg
     6181 gaacgtttta cgaagattag atccagaaaa catcgaagat attgccgcag tcaatgcatt
     6241 gtatcgacca ggccctatgc aaaatataga taccttcatt gccaggaaga aaggaaaaga
     6301 agccattcgc tacccagatg attcactgat cccgattttg aaaaacacat atggagtgat
     6361 cgtctatcag gaacaaatca tgcagatcgc ctcgactatg gctggattta cattagggca
     6421 gtcagatatt ctgcgacggg cagtgagtaa aaagaaaaaa gacgtattag atgaagaaaa
     6481 gtcgcatttt gtatcaggag cattacaaca gggatattcg gaaaaaacag cagcgaccgt
     6541 atatgaatat atcgaaaaat ttgcaaacta tggattcaat cggtcacatg catttgctta
     6601 ttcattcgtg ggattccaaa tggcgtatct aaaagcccat catccaggtg ctttctttac
     6661 cagcctgatg aattctgttc ggcataacac atcaaaattg aaagaatata ttgcagaagc
     6721 acgtaaaaat aaactcaaac tttcctcgcc gtccattaat caaagtaatt ccagttttga
     6781 gttggtcaat aaggaagaaa tcagattcgg actgacagcg ataaaaggta ttcggcgtga
     6841 ttttgtagaa gatatattaa acgaaagaaa acaaaatggc ccgttccagt cagtggatca
     6901 attcctcata cggatcgata agcgttggct gaaattagag ttactgcaat cactgacagc
     6961 agtaggagtt tttgatgaat tatctcctaa caggaaacaa ttgatgcttg atctcgaagg
     7021 aaaaatccaa aatatcgttt acagtggtgg aagtcttgac ttgctgggaa tcatggcatt
     7081 aaaagaagaa gaagtcgctg actatacact agaagaacgc ttgaagctgg aagaggagta
     7141 cttaggtatt tatttgtcag gtcatcctgc agaagggttt gatcgtcttc gtttagctaa
     7201 acaagttcag ctgattacag atatcgtccc taatcaacca gtcaatttat tagtgatgat
     7261 caaggaagtt agagaaattc ggacaaaaaa aggagaactg atggcctttg ttgaaggaac
     7321 cgacagtagt ggagaaattt ctgtcacagt ttttccaact ctttatcgta aatatcgtaa
     7381 tttgtttgcc gttgatcgag tgatctttgt tcaagggcgg agcgaaatca gcaaatataa
     7441 tcaggaactg caactaattg gagaaagctt tgctgatcct aaccagttag aagcccagta
     7501 tccttcacaa acttgctatt tgcgtattac agaagaacgg gaagatcccg agataatgaa
     7561 acaattacaa gtgatttttc agaaacaccc aggatatata ccagtagtta tgtatcacga
     7621 aaaaacgcaa cgaaaagtag ttctgtcaga tgcttattgg gtggatgaca gcaagagtat
     7681 aaagcggcaa cttatttatc tgcttggcga agataatgtg gttttcaaat aacttacggt
     7741 aaaaaatact acttgctttc attttttttc atttttttat ccgtaaatca agacaagtga
     7801 gaaaaataat gttagaatgt tagtcgtggt taacgcaaaa atggttgtaa acctaagtca
     7861 tacttaggat aaagtatttt aatgaggtga atgtttatta tgaaacgcat cggaattttg
     7921 accagtggcg gagacgcacc tggaatgaat gcagctgttc gtgccgttgt tcgtaaaggt
     7981 atttacgaag gactggaagt atacgggatc aattatggtt ttgccggttt agttgctgga
     8041 gatattcgtc gtcttgatgt ggcagatgta ggtgacaaga tccaacgtgg tggtacattc
     8101 ttgtattctg cacgttatcc agaatttgca actgaagaag gtcaattaaa aggaatcgaa
     8161 caattgaaaa aattcggaat cgaaggtcta gtggttatcg gaggagacgg ctcttatcat
     8221 ggcgcaatgg ctttgacaaa acgcggtttc ccagcagtag gtattcctgg aacaatcgat
     8281 aatgatattc ctgggactga tttcacaatc ggttttgata cagcaatcaa tacagtacta
     8341 gaatcaattg accgtattcg tgacacagcg acttctcatg ttcgtacatt cgttatcgaa
     8401 gtaatgggac gcaatgcagg agacatcgct ttatggtcag gtgtggctgg cggagcggat
     8461 gaaatcatca tcccagaaca tgattttgat atggcttcag ttgctaaaaa aatccaagaa
     8521 ggccgcgatc gcgggaagaa acattgcttg atcatcttgg ctgaaggtgt aatgggcgga
     8581 aatgaattcg ctgagaaact ttcagaattt ggtgactatc atacacgtgt atctatcttg
     8641 ggacacgttg tccgtggtgg agcaccaagc gcacgcgacc gcgtgttggc aagtaaattc
     8701 ggtgcttacg ctgtcgaatt gcttcaagaa ggaaaaggtg gattatgtgt cggtatccat
     8761 gacaacgaaa tcgttgcgtc tgacatcatt gatacacttg aaaacaacaa acataaacca
     8821 gacttatcac tatatgatct aaataattca ctttcatttt aagagtgaaa gaaaccaagc
     8881 tatttaagct gtgtacagct ttaaataaac aaaattgaat gggagagttt tttaaatgaa
     8941 aaaaaccaaa atcgttagta cattaggacc agcaagtaac tcagtagaaa ttatttctca
     9001 attgattgaa tctggggcaa atgtcttccg ctttaatttt tctcatggtg accatgaaga
     9061 acaattatca cgtatgacta tggtccgtga agcagttaaa aagacaggaa aagatgtcgg
     9121 tattctttta gatacaaaag gagctgaaat ccgtacaact gttcaaggca caacagaagc
     9181 tgattttggt cgtgcaggat acatcaaatt tgaagtagga gatcaaacac gcatctctat
     9241 ggatcctgaa catgtaggtt caaaagaaaa aatcgcggtt acttacccag gattatttga
     9301 cgatgttcac gttggcggac acattttatt tgatgatggt ttgatcgata tgcaaatcat
     9361 tgaaaaagac gaagcaaacc gtgaattagt cgtagaagtt aaaaatgcag gtatgctagg
     9421 atcacgtaaa ggggtaaatg caccaggcgt ttctattagt ttgccaggta ttactccaaa
     9481 agatgctgac gatattcgtt ttggtttaga caacgatatc gactttatcg ctgcaagttt
     9541 tgtacgtaaa gcacaagacg ttctagatat ccgcgaaatc ttagaagaaa aagacatgac
     9601 tcatgttcaa atcttcccta aaatcgaatc tcaagaaggt atcgacaaca ttgacgaaat
     9661 catcaaagtt tctgacggtg ttatgattgc ccgcggagat atgggtgttg aaatcccagc
     9721 tgaactagta ccaatggttc aaaaacgcat tatcaaaaaa tgtaatgctg ctggtatccc
     9781 agttatcact gctacacaaa tgttagaatc aatgcaagaa aacccacgtc caacacgtgc
     9841 ggaagcttct gacgttgcta acgctgtatt tgatggcaca gatgcaacaa tgctatctgg
     9901 tgaatctgca aacggggact acccagttga agctgtttca acaatggcac gtatcgacca
     9961 agaagctgaa aatgcattat cagaattagg tacattccaa ttgaacgaat tcgataaaac
    10021 agatgtaact gaaacaatcg gtttatctgt agctcgtgct gcaaaaaatc taggcgtgaa
    10081 aacaatcgtt gctgcaactg aatcaggata cactgcaaaa atgatttcaa aatatcgtcc
    10141 agatgcagat atcttggctg ttacttttga cgaacgcaca aaacgtggtt tgatgttaaa
    10201 ctggggcgtt tacccaacag ttgctgaaaa accatcaaca actgatgaaa tgtttgaact
    10261 agcagctaaa aaagctgttg aattaggttt cgcatcagaa ggcgatttaa tcttgatcac
    10321 tgctggtgta ccagttggtg aacgcggaac aactaacgtg atgaaaattc aaatgattgg
    10381 ttctaaatta ttagaagctc aaggcgttgg acaaaaatct gtcgttgcaa atgcagttat
    10441 tgcttcatct gctgaagaag ctgtaaaaaa agcaaaagac ggaatggttc tagttgtacc
    10501 atcaactgac aaagaatata tgcctgcaat cgaaaaagca gctgctgtta tcgttgaaga
    10561 aggcggattg acttctcacg ctgcagttgt aggaattgca caagatattc ctgtaatcgt
    10621 tggtgctaaa ggcgcaacaa caacaattac agaaggtgaa ttgattaccg ttgattcacg
    10681 tcgcggcatc gtttaccgtg gcgaaacaac agctatctaa tttagcttaa taaaaaataa
    10741 aaacagctct tcttttacga agagctgttt ttttgtgctg taacgaattc atggataact
    10801 tggactactt gttcttgaag aggcgtgacg atctgctgtg ttcgttttgc caatgaaatc
    10861 aagaagcgag gctgaacttc atctgaaaga gggaggcaaa ctaaatgatc ttcaggatgg
    10921 acagcaatct ctgccaaaaa accgataccc acattttctc ggaccatact ctttaaaatc
    10981 gtcaagtcat tgctttgata aacaactttt ggatgagtat gtgtttgttt agaaagctta
    11041 gtgaatgctg cggggtggac ataatgttcg ttcaatagta caaactgttc atctgctata
    11101 tctttgaaag agacagtatc ctgcttggaa agaggatgtg taggtggcac gacgatcatg
    11161 aaacgtttgt ccaaaagtaa ctctgtttct aaatattgat ccacgattgg ctgtgttgag
    11221 cctaatacag ctaaatcgat cctcccttgt cggatcatcc cgtataagtc ccgagagcct
    11281 ccatcggtaa tctcaatttg attcatcaat tcatgcttga taaagtaact tgacagttta
    11341 ggaaagtatt cattgccgat aataggaggc atgccaaaac gaagcttttt cttttgcaac
    11401 tgagtgattt cagctcttgc agtagaaatc tcttggagaa tggtttgtgc atggagaaac
    11461 agctgctttc cagaaggcgt gacgattaat tcgtgatgcg atcgatctct tgtaataagt
    11521 acggtgtcaa actctttttc aagacgttgt aatgcatatg taatagtagg ttggctcaca
    11581 cggaaataat tagccacttt cgtaaaattt ttttgtttga cgatttggac atagtattcg
    11641 atatctttcg tgttcatgaa gatcatccgc tcctttaatg gaataatgat tattgtaaat
    11701 gattctgagg atgatagcaa acagaggctt tctaataaag atttttctgt ttttttatga
    11761 actgcaaggt gtcaagaaaa tttcattgac aacatgcttt ttgccctgta taattgcttt
    11821 tgttgcttag gagtgatgaa aaatgaaatg gtctttattg gaattgagaa aataccagga
    11881 gacaccgtta acttttcatg agacgctcga cttgaaagcc gctctcatga agcgagacaa
    11941 tttaatactt gatgttgcgc cagtggaagt cgaaggtttg gtctcagttg ataagaaagg
    12001 ctatatcgtt cattacactg tgcagacgac tttgacagtt ccttcaacac gttcactaga
    12061 acctgttgaa ctgcccatgg atttttctgt agacgaagta ttcatgacag aagaacaatt
    12121 ccaaagtaga gatgaacaaa tgtctgcgga tgagattttg ctaattgaag gtccattatt
    12181 gaatttagca gagtcgattg aagacaacat cttattggcg attccaatgc gggtattgac
    12241 aaaagaagag gaagcagcaa cagaacttcc aaaaggcaat gattgggaag ttgtttccga
    12301 agaagaatac cagcgcagaa aaatggaaga agccgagaat aaaattgatc ctcgtcttgc
    12361 aaaactatct gaactttttg attctaaatc aaaagacgac gataacaagt aagattggaa
    12421 tatattgtgt ctaatttaga tacaagactt tacaaggagg tgtagcaaaa tggcagtacc
    12481 agctagaaga acatcaaaag ctaaaaaagc aaaacgtcgt acacactaca aattgacaat
    12541 caaagggtta aacgaatgtc caaactgtgg tgaaatgaaa aaaagccatc acgtatgtgc
    12601 aaattgtggt tactatgatg gtaaggacgt aatgtcaaaa gaagcttaat acattttaat
    12661 tagaaaatgt aaaacctcaa ggctaaccat ggagccttga ggtttatttt tttgtagtcg
    12721 gtaaataaaa aatatgttgt tctttagttt gcaatgtagc cgtgttaagc tataatgtaa
    12781 gagattaggg agaaatcccg tatgtaggag gagttcatat gtcaaaacaa caaatcggcg
    12841 ttgtcggtat ggccgttatg ggtaaaaatc tagccttgaa catagaaagc cgcggctatt
    12901 cagtggcttt attcaatcgt acaggggcta aaacaaccgc tgtagtagaa gaacacccag
    12961 ataaaaattt caaagcaaca tatacaatcg aagaatttgt agaatctatc gagaaaccac
    13021 gtcggatctt gctaatggtc aaagcaggac cggcaacaga tgcaacgatc caagagttgc
    13081 ttcctcacct tgataaaggc gatattttga ttgacggagg aaatacattc tttaaagata
    13141 cgatgcgtcg taatgaagag ttagccaact ctggcatcaa ctttatcggt acaggcgttt
    13201 ccggtggtga agaaggagct ttaaaaggac cttcaatcat gcctggtgga caaaaagaag
    13261 cctatgcgct agttgcacca atcttagagc aaatttctgc aaaagcagaa gacgaagcac
    13321 catgtgtcac atatattggc ccaaatggag ccggacatta tgtgaaaatg gtacacaacg
    13381 gtattgagta tggagatatg caactgattg ctgaatctta tgacttaatg aagaatattt
    13441 taaacctttc agtagaagaa atggctgata tctttaaaga atggaatcaa ggcgaattag
    13501 acagctattt gatagaaatc actgctgaca ttctgacacg taaagacgat gaaggaacag
    13561 gtaaaccagt agtagatgtg atccttgatg cagctgggaa taaaggaaca ggtaaatgga
    13621 caagccaaag cgcgcttgac ttaggtgtgc cacttccatt gatcactgaa tctgtatttg
    13681 cccgctatat ttctgcttat aaagaagaac gcgtacaagc aagcaagatt ttatctcgta
    13741 cgaacgattt tgagttcacg ggagacaaaa aagaattggt cgaaaaaatc cgagaagcgt
    13801 tgtatttcag taaaatcatg agttatgccc aaggatttgc tcaattacgt gtcgcttcaa
    13861 aagaatttga ttgggacttg ccatttggtg aaatcgcaaa aatctggcgc gctggatgta
    13921 tcatccgagc tcgattcttg caaaaaatta cggatgccta tgacaaaaat cctgagatcg
    13981 aaaatttatt gctagatgat tacttcgttg aaatcacgaa aaaatatcag caatcagtca
    14041 gagacgtcgt tgccttggct gtccaagctg gcgtacctgt accgactttc tcatcagcca
    14101 tcgcttactt cgattcatac agagcagaac gtctgcctgc aaatataatc caagcccaac
    14161 gcgattactt tggcgcacat acctatgaac gtgtcgacaa agaaggaatc ttccattact
    14221 catggtacca tgaagaataa tagtctttcg gctgttagga aatgagaaaa taaaaagagg
    14281 acgaaagagc tgaagtcgat tgttatgagt agacttcagc tcttttttaa aattgctatc
    14341 catgataaaa tgactataga tttttaagca tattatcggt ataatgatag agtttttaaa
    14401 aagccagtag aatagaaagg ataaaataat aaatgagcaa tattctaatc attgaagatg
    14461 aaaagaactt ggcacgattt gtcgagctag agttgaagca tgaagggtat aacgcagaag
    14521 tccactacaa cggccgaact ggtttagatg cggcattaaa taatgagtgg gatgccatat
    14581 tgttggatct gatgctccca gaattgaacg gtttagaagt ctgcagacgt gtacgccaag
    14641 tcaaaaatac accaatcatt atgatgactg caagagattc tgtgatcgat cgtgtatctg
    14701 gacttgacca cggagcagat gactacatcg tcaaaccatt tgctatcgaa gaattattag
    14761 cacgtcttcg tgcattgttg cgtcgaatcg atattgaagg cgataaaaat gtggctaaac
    14821 aaactactat tacttatcgc gatttgacta tcgaaaaaga aaaccgtgtc gtacgtcgcg
    14881 gaaatgaagt aattgaacta acaaaaagag aatacgagtt gctgcttact ttaatggaaa
    14941 acgtgaacgt ggtattagca cgtgacgttt tactaaataa agtgtgggga tacgaaacag
    15001 aagttgaaac aaacgtagtg gacgtatata ttcgttatct tcgcaacaaa attgacgttc
    15061 ccggggagga aagctatatc caaactgtac gcggaacagg ttatgtgatg cgctcgtgat
    15121 aaagccgaaa aaatcggaaa aaagagaact gaaagggccc tccttgacaa tcaagtgggc
    15181 ctttgcgagt tctttcttca tattcgttgt gtttacaatt ttcgctgtca ttacctataa
    15241 atcatctatc aatctgattg tggcaaaaga aagaaacaat gtagagcgta cgatttcaga
    15301 agtagcttct cgtttggcta actcggatga agaactgaca ttagtaaata cgtatcgtaa
    15361 tctgacgaaa gcgacaaatg acggagatga ggtcgtagat catacttcac tggtcgaagg
    15421 aaacttaatg aagatcgatt cctttatagc tgagctaggg cagccatcaa tggatcttta
    15481 tgtttatgat ttggacgaga acttgatttt taaaacccat gaaaacagtc gaaacctgat
    15541 tcagactaca cgtaaagttc caacgatcgt tacactagaa ggaaaaactg gctttttatc
    15601 tatccagcct atatattcta aaggtacaag agaaaagatc ggctatgcgc aaagcttcta
    15661 tgaattatct tctttctatg atattcgaaa taagctatta ttgactctta ttgttttaga
    15721 agttgtttct ttgatcttaa gtagtatttt aggtttcttt ttatcttctt atttcttaaa
    15781 accactcaag gtactcagag atacaatgga tactatacgt aaagatccgc aatcagatat
    15841 ccacatgcct gaaatcgaca caaatgatga attggcagat ttagctgaaa tattcaatga
    15901 gatgcttgac cgtatgcgtt tgtatattga acaacaagag caattcgtgg aagacgtatc
    15961 tcatgagtta aggacacctg ttgcaattat tgaagggcat cttagtctgc taaatcgttg
    16021 ggggaaagat gatcctgaga tattagaaga atcattaagc gccagcatgc aagaaattag
    16081 ccgtatgaaa agcttagttc aagagatgct agacttatca agagcagaac aagtagatgt
    16141 tcattatgcg aatgaaacaa ctaaaggaaa agaagtcacc tatcaagttt ataataattt
    16201 caagatatta tatccagact atgtgatcac tttagatgat gatttgacaa aagaagtgac
    16261 cctgcaaatt tatcgtaatc actttgaaca attaatcatt atcatattgg ataacgcagt
    16321 aaagtattca actacacgaa aagaagtcca tatctctatt tcttccactc tgaatgaatt
    16381 tgagatcgcg attcaggact ttggcgaagg aatacccaaa gaagacctta ataagatctt
    16441 caatcgtttt tatcgagtgg ataaagcaag agctagaacg aagggtggaa atggtctggg
    16501 gttgtctatc gctaaacaac tggttgaaaa ctataaagga cgtatcttag cagaaagtgt
    16561 agtagggcaa gggacaattt ttagaatctt tattcctatc gcaaaggcag aagacaagta
    16621 aagcatgtgc tttacttgtt tttttatata tccaacaaag aataaggtac aaaatacaag
    16681 caagttagaa attcagggat gtcattataa aaaaaactag cgaacaatta aatagaataa
    16741 catccgttaa ttaaacgtaa gtagctttta gatgaacgaa aaaacaatga aatgctgtaa
    16801 tattcgtgtt taaaaataat aaataaaaat agggaatttt ctattgcaat tttataaaga
    16861 gattgctata ttattatttg ttctaaatga ttcctttaag gtgtcactaa aaattataaa
    16921 aaatagggtt gacgcacttt tgatgtcatg ttataataac gaagtcgttt ggatgaggta
    16981 gctaataaag cttgatttta tcgaaaaaaa cttcgaaaaa gttgttgaca aataacaata
    17041 aagatgatat gataatcaag tcgctgctaa tgagtgacaa agacgtttag aaaaaataaa
    17101 caaagaagtt gttgacattc tcttctgaat ctgataagat taaagagttg ttgaaacaaa
    17161 aaga
//
LOCUS       DBGZHO010000056        17007 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.059, whole genome shotgun sequence.
ACCESSION   DBGZHO010000056 DBGZHO010000000
VERSION     DBGZHO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.059"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..126)
                     /locus_tag="ACN3HL_002134"
     CDS             complement(<1..126)
                     /locus_tag="ACN3HL_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HHC8006967.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="ACN3HL_002135"
     CDS             complement(230..541)
                     /locus_tag="ACN3HL_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HHC8006968.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="ACN3HL_002136"
     CDS             complement(543..740)
                     /locus_tag="ACN3HL_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HHC8006969.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="ACN3HL_002137"
     CDS             complement(1134..2861)
                     /locus_tag="ACN3HL_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HHC8006970.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="ACN3HL_002138"
     CDS             complement(2854..4047)
                     /locus_tag="ACN3HL_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HHC8006971.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="ACN3HL_002139"
     CDS             complement(4234..4878)
                     /locus_tag="ACN3HL_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8006972.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="ACN3HL_002140"
     CDS             complement(4972..5106)
                     /locus_tag="ACN3HL_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HHC8006973.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="ACN3HL_002141"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="ACN3HL_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HHC8006974.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="ACN3HL_002142"
     CDS             complement(7237..7710)
                     /locus_tag="ACN3HL_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HHC8006975.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="ACN3HL_002143"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="ACN3HL_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HHC8006976.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="ACN3HL_002144"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="ACN3HL_002144"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HHC8006977.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="ACN3HL_002145"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="ACN3HL_002145"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HHC8006978.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="ACN3HL_002146"
     CDS             complement(11757..12896)
                     /locus_tag="ACN3HL_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHC8006979.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="ACN3HL_002147"
     CDS             complement(13205..13918)
                     /locus_tag="ACN3HL_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HHC8006980.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="ACN3HL_002148"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="ACN3HL_002148"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HHC8006981.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="ACN3HL_002149"
     CDS             15107..16639
                     /locus_tag="ACN3HL_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHC8006982.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="ACN3HL_002150"
     CDS             complement(16830..>17007)
                     /locus_tag="ACN3HL_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8006983.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DBGZHO010000057        16443 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.060, whole genome shotgun sequence.
ACCESSION   DBGZHO010000057 DBGZHO010000000
VERSION     DBGZHO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.060"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..351
                     /locus_tag="ACN3HL_002151"
     CDS             <1..351
                     /locus_tag="ACN3HL_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8006984.1"
                     /translation="LKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNLFLFDEPT
                     SGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKKDIKLRVE
                     DSTLIEQIFNDITK"
     gene            369..938
                     /locus_tag="ACN3HL_002152"
     CDS             369..938
                     /locus_tag="ACN3HL_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HHC8006985.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            1048..2802
                     /locus_tag="ACN3HL_002153"
     CDS             1048..2802
                     /locus_tag="ACN3HL_002153"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006986.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            2762..4528
                     /locus_tag="ACN3HL_002154"
     CDS             2762..4528
                     /locus_tag="ACN3HL_002154"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8006987.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            5051..5320
                     /gene="rpsN"
                     /locus_tag="ACN3HL_002155"
     CDS             5051..5320
                     /gene="rpsN"
                     /locus_tag="ACN3HL_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HHC8006988.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            5335..5514
                     /gene="rpmF"
                     /locus_tag="ACN3HL_002156"
     CDS             5335..5514
                     /gene="rpmF"
                     /locus_tag="ACN3HL_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HHC8006989.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            5546..5923
                     /locus_tag="ACN3HL_002157"
     CDS             5546..5923
                     /locus_tag="ACN3HL_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8006990.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            5944..6093
                     /gene="rpmG"
                     /locus_tag="ACN3HL_002158"
     CDS             5944..6093
                     /gene="rpmG"
                     /locus_tag="ACN3HL_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHC8006991.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            6117..7100
                     /locus_tag="ACN3HL_002159"
     CDS             6117..7100
                     /locus_tag="ACN3HL_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HHC8006992.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            7130..7252
                     /locus_tag="ACN3HL_002160"
     CDS             7130..7252
                     /locus_tag="ACN3HL_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HHC8006993.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            7270..8793
                     /locus_tag="ACN3HL_002161"
     CDS             7270..8793
                     /locus_tag="ACN3HL_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HHC8006994.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            8817..9056
                     /locus_tag="ACN3HL_002162"
     CDS             8817..9056
                     /locus_tag="ACN3HL_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006995.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(9249..9710)
                     /locus_tag="ACN3HL_002163"
     CDS             complement(9249..9710)
                     /locus_tag="ACN3HL_002163"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHC8006996.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(9905..10123)
                     /locus_tag="ACN3HL_002164"
     CDS             complement(9905..10123)
                     /locus_tag="ACN3HL_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8006997.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            10241..11857
                     /locus_tag="ACN3HL_002165"
     CDS             10241..11857
                     /locus_tag="ACN3HL_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HHC8006998.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(12098..13438)
                     /locus_tag="ACN3HL_002166"
                     /pseudo
     CDS             complement(12098..13438)
                     /locus_tag="ACN3HL_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(13714..13869)
                     /locus_tag="ACN3HL_002167"
     CDS             complement(13714..13869)
                     /locus_tag="ACN3HL_002167"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HHC8006999.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(13876..14022)
                     /locus_tag="ACN3HL_002168"
     CDS             complement(13876..14022)
                     /locus_tag="ACN3HL_002168"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007000.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            complement(14061..14255)
                     /locus_tag="ACN3HL_002169"
     CDS             complement(14061..14255)
                     /locus_tag="ACN3HL_002169"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHC8007001.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(14165..14497)
                     /locus_tag="ACN3HL_002170"
     CDS             complement(14165..14497)
                     /locus_tag="ACN3HL_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8007002.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(15011..15202)
                     /locus_tag="ACN3HL_002171"
     CDS             complement(15011..15202)
                     /locus_tag="ACN3HL_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007003.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(15296..15682)
                     /locus_tag="ACN3HL_002172"
     CDS             complement(15296..15682)
                     /locus_tag="ACN3HL_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHC8007004.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         5514 a         2467 c         3128 g         5334 t
ORIGIN      
        1 ttaaaaaaaa tggaacttta taaaatgaaa gatcaattac cgtttgattt atccggtgga
       61 gaaaaacaaa gattattggt ttctatagct tcattgtcaa aaactaattt atttctattt
      121 gatgaaccta caagtgggtt ggattatatc aatatggaaa ggattgctga ccttattaaa
      181 gacttaaaag aaaagggtgc agtagttata gccactcatg atccggaatt tctttataaa
      241 acatgcaata gaattattta tttaaaaaat ggtggaataa aaaaagatat aaaacttaga
      301 gtagaagatt caactttgat agaacagatt tttaatgaca taacgaaata gaattgagga
      361 gaatatatat gaaaacaaaa gattatattt ttattggttt agctacagtt atttccctag
      421 taatttactt tttttcaata atggttagta gtattggtgg ggcgtttggt cacagcatat
      481 ccccagggat ttttggatta ttatctggaa tcatatttgt ttatattagc tataactacc
      541 ctagaaaagg aatttttact atttacacaa ttgttttatt gttatttttt acgttaatgg
      601 gcggggcgta cttaccttgg tttatcagtt cgattagtat ggcgatctta gctgatatta
      661 ttctatctgt atttggatat gatcgagcaa ttcctcaagt tgtgtcttgg gttctaatgc
      721 aactaggcag tgctgccgga cagtggattc ccatatggtt ctttacagat cgttttcgtc
      781 aagactggat agatagagga caatctgctg caacaatgga tgcaatgatc cactacgcgg
      841 tgggtatatg gggaattatt tcagtgttag ttgtagcaag tttatctatg attggtgtat
      901 tgattggaag aaaagtctta aaaaaataca aaaaatagaa cgtagtttac cttctatctg
      961 tttgtacatc tctaatttac gctattacgg aaagcattaa cagttgtaaa cgaataagag
     1021 aagaaattga atgcggggga ggaaaaaatg aaagtataca aaaaattatt tagttatgtc
     1081 cctaaaatga aatactacgg atggttagcc actttatttt ctgatttttc tgtcgtatta
     1141 acagtctatg gatattacag tatttacaaa tttcttcagt ctctaattat tgtaggagat
     1201 gaatatttag ctaagagtta tgcggttcaa actgttgctt ggttaacttt aggagcttta
     1261 ttttatattt tttctggctt attttctcat atccttgggt ttcgcttaga gactaatttg
     1321 agaaaaaagg gaattagcgg tttaacagaa gcaagttttc gtttttttga tttaaattct
     1381 tcgggatata ttcgaaagac aattgatgac aacgcggcta aaacacatat ggcaattgct
     1441 cacttgattc cagatagtgc tcaagccata gtaacacctg ttttatcagt tgccttaggc
     1501 tttttcatta actttaaaat tggattggtt ctaatcgcca tgttagtaat tggtgtattc
     1561 ttgttaaaga aaatgacaga gaatacaaat tttattcaaa aatatcaaga atcgttagat
     1621 gtgttaagct ctgaaacggt agaatatatc cgcggaattc aagttataaa gatatttggt
     1681 gctaaagtaa catcatttaa agccttgaat aaagcaatta acgattatgc taagtttgca
     1741 tataagtatt ctttgagtgg gaaaacacct tttgttcttt ttcaatggct attttttggc
     1801 atagtttgca ttttgatagt tcctataacc ttttttataa cttctcttac cactcccaag
     1861 atcttagctg ttgacttgtt gatgttgttt tttttaagtg gaattatttt tgtttctttc
     1921 atgagaataa tgtatgtaag tatgcacttg tttgaagcaa gatatgcagt cgaaacacta
     1981 gactcccttt atttagaaat gaagcaagac caactaaaat atgggaacga gacacagatt
     2041 aaaaattgtg acattgcatt tgaaaatgtc agcttttcat acaaagaaga gtgtgtttta
     2101 gaaaatttca acttagtttt agaacaaaaa agaatttatg cattagtagg aaaatcagga
     2161 agcggaaaga gtacgatagc taaactaatt tcaggtttct acaatgtgga taagggacag
     2221 attaaaattg gtggtaagcc tttaaatcac tattcaaaag acacaattat taacacaatt
     2281 gcttttgtct ttcaagatac gaaactattc aatcagagta tttacgataa cgtttctata
     2341 gcaaatcctc aagcgccagc aagtaaagta tttgacgcgc taagattagc cggttgcgaa
     2401 tcgattttag aaaaatttcc cgaaagagag cataccttaa ttggtagtaa aggagtttat
     2461 ctgtcaggag gagaaaaaca acgtatagct attgccagag caattttaaa agatgcaaag
     2521 attgttatta tggatgaagc cagtgcatct attgatccag ataatgagta tgaactacaa
     2581 aaggcttttc aatatttgat gaaagaaaaa acagttatta tgatagctca tcgattatcc
     2641 agcattaaat ctgtagatga aattcttgtc ttgtcagaag gaaaaatagt agaacgtgga
     2701 aatcataatg aattaatggc taaacatcga gtgtataaac aattggtcac taattatgag
     2761 aatgcaaatg attggaggct tgacaatgaa aaatttttat aaaaaaaaat ttgctttaac
     2821 tgatcagggc gcagaagctt taactaaagc ttctatttct agtttttttg tatactgcat
     2881 taatatggta ccagcattca ttataatgat gctgatagac gaattagttt tagaaaatgc
     2941 aaagccccgt tggctttatt ttgcagtatc gtttgttact ttgcttttca tgtattggtt
     3001 gttagatagg gagtatgaaa acttatataa tagtacttat aaagaaagtg cgcatttaag
     3061 agtgcaaatt gcagacgatt tgtcaaattt accattatcc tatttttcaa aacataattt
     3121 atcagattta tctcaaacta tcatgtctga cgttgaaggt attgagcatg cgatgagtca
     3181 tgcaatacct aaagccggcg gtatggctct gtttttccct tttatttcag tgatgctttt
     3241 ggttggtaat gtcaaaatgg gattagctgt tattttgcca acgttattta gttttgtctt
     3301 aatcttgtta tcaaagaaat cccaaacgaa agccaatact aaatattacg atactttgag
     3361 agaaaactcg gaagaatttc aagaaactat tgaattgcag caagagatta atagctttaa
     3421 tctatctaaa aaagttcaag acagactttt caaaaaaatg gaagagagtg aaaggattca
     3481 tttaaaggta gaattaagta ctttttcagt catggcctta tcctctattt tctcatatgt
     3541 tagtttagca gtagtcattc tagtaggtgt tcacttactg ttaacgggtg aagtgactat
     3601 actctacgtc gttggttact tactagccgc aataaaaata aaggattcct tcgattctat
     3661 gaaagaagca gtgcttgaaa tattttattt agctcctaaa atacagcgaa ttagagctat
     3721 gaaggaaacc agtatccaag agggatcaga tagtcctctg aaatcttttg acattgagtt
     3781 gcgagatgtc tctttctcat atgataacaa taccccaatt ttagatcata tctcttttac
     3841 ggctaaacaa ggagaagtga ctgcgttagt aggtgctagt ggttccggga aaactagtat
     3901 cttgaaatta gtgtctagac tgtatgatta tgatgaaggc tgtattttaa ttgatgggta
     3961 tgatattaaa cgtgtatctc cagcttcttt gtttagcaaa atcgctattg tttttcaaga
     4021 ggtaactttg tttaatacaa gtattttgga aaatatacgt attggaaata gtcaagcgtc
     4081 agatgaggaa gtgaaaaaag cagctcgttt agctaactgc gaagacttta ttgaaaaact
     4141 acctgacggt tatcatacat tggtcggaga aaacggaagt tcactttctg gaggagagcg
     4201 acaacgccta tccatagcac gggctttttt gaaaaatgcg ccaattttaa ttttagatga
     4261 aattactgcc agtttagatg cggaaaatga aaaacgtatt caggaaagtt taaatcgttt
     4321 aatacaagat aagacagtac taattatatc gcatcgcttg aagtctattg aaaaggtaaa
     4381 taaaattgta gtgatggatc aaggaaaact agttgatcaa ggtactcata atgagttgta
     4441 tcgaaggtca gaaatataca aaaatctcat aaagaaaact aaactatctg agaaattcgt
     4501 ctatgaaaaa gaagctcaat cacgatgatg aaataggctt taaattaacc tacaattttt
     4561 gggatatagt tataattctt tttcaaaaag aataatttta ttaaacagca tctaattttg
     4621 aatacacgaa agaatcagta tgattgaatt agttcactta atgtctattc ttataatata
     4681 aggaataatc aaagttttaa aaaattggcg ataaaccagt taaacataaa agattgaata
     4741 aaaagttata gtttctttca tattgccgtt ttaagtagag gaaaagctac ttaaaacggt
     4801 atttgtgttt gattggacta ataaaagtga attcttattt ttcagagcct aaactgcata
     4861 ttcttttaaa tgatttgatt atctctatgt accgataaat tcgttttcaa atagttatct
     4921 attcatatga gttttatttc atgttattta ttgttgacaa gagcaactct tgttggtaaa
     4981 gtatcagtgt caaaacgtaa cgattacgat ttgaggtgtc taaatcaaaa taaaaggagt
     5041 ataaaggtat atggcaaaaa agtcgaaaat tgctaaagca aagaaacaaa tggcgatgat
     5101 tgaaaagtat gcagataaac gtcaggaatt aaaagccgca ggagatcgca ccgctctcgc
     5161 taaattgcca agagattcaa atccgaatcg tctgaggctt cgtgatcaga cggatggtcg
     5221 tccaagaggg tatatgcgaa agttcggtat gtcccgtatt aagtttagag aacttgccca
     5281 tcaagggttg attcctggag taaaaaaagc aagttggtaa aaggaggaaa tatcatggca
     5341 gtaccagcaa gaaaaacatc taaggcgaag aaacggttaa gaagaactca tcaaactgta
     5401 gtaaaaccag aaatttcatt tgacgaagcg aatggtgatt atagacgtag ccatcatgta
     5461 tctttaaaag ggtactataa tggaaagaaa gtaattaaag gagcttcaaa atagtttaat
     5521 atataacttt taggagggaa tcaaaatgga aattatttac ccacctttag ttgaagaagg
     5581 attaaagtat tatcttgaaa cgacccagca atcgctagat aaatgcactt tttatcgttc
     5641 gatggtagag agaggaatta ttactgaaac gggtttaccg acccaacagg caattgaaaa
     5701 tggattagtc aaagattact atgaggacca aggcttatca tttgatgatt ttttaagaat
     5761 ctatccaatt tttgaagagt atgacgagga gttatttcaa tgtatcgatg gttattggga
     5821 gatacctgtt gatatgaaag aaaatttagt ttcacaattg gaatctggcg agttaacttt
     5881 tgaagatgca caacaaattc aagcatatct tgaagatcga taagtattga aggaggaaga
     5941 tttatgcgtc aaaatattat tttggaatgt gtcgaaactg gagaacgtct gtatctcacc
     6001 agcaaaaata aacggaataa ccctgaacgg ttagaattaa aaaagtattc gccaaaattg
     6061 cgcagacggg caatttttaa agaagtgaaa tagctaagtg gtaaaaaggt gacaaaatgg
     6121 gcataccagt tacaatcgtt tctgggtttt taggggctgg aaaaacaacg ctaatcaatc
     6181 aagccttgca agtctcaccc taccccaggg aagaaattat tataattgaa aatgagtttg
     6241 gtgaagttgg gattgatcac aaattattag ttcatagcga ggaacgggtg ttacaactaa
     6301 ataatggatg tatgtgttgc agtcttcgca gtgatttatt agcaatattg atttctttac
     6361 tggaaacaat agaagaacat caacaaccaa tttcacaaat catcattgaa actacaggta
     6421 tagcagatcc ccaaccaatc attcaaacac ttttaacagc gcctcaacta agaggaagag
     6481 tatatatcga tagtttattg actgttattg atagtgacag ttttgaactt attgaaagag
     6541 aaccacaagc ccttaagcaa cttgtcatgg cagatcgcat ttttgtgtct agaaaacaaa
     6601 acttgaattt atctgcacta aaaaaattac agagagaaat caaaagtatt aaccctttat
     6661 ccgatattcg aatgttcaca catagtgaaa cgattcaaaa aaaggatttt tataatttga
     6721 aaaaatttaa tcatccctta gtttttgaaa gtgattcatc agaaaatcac tataatggca
     6781 aatactatca tcaacaccat caagtacatg agtttaaatc aattctctta acttcagatc
     6841 aagacataaa aaaagatttt ttactccaat ggattgactg gctgatttta accaaccaag
     6901 ggagcctgta tcgttttaaa ggattgattg ctttacaaga gcaggatttt atagttgcca
     6961 tgcaagaggt aaacgaacag gttaattttc aatacaccac tcgacaaaaa gaccaaacca
     7021 ctattattct aatcggaaaa atgttggatg aagaaaggat caaacagagt tttgataaat
     7081 tactggcgga aagcaaataa tgataagtag tgattggggg taatttctaa tggagaaaac
     7141 ggatatatct agtgcatatc gacgacttaa aagcccgaat attaaaacta gaaaaagggc
     7201 attaaaaatt atcaaagaac ataaacgaaa taaaatgaag aaattagcat aattaaggaa
     7261 ggaaaaagaa tgaagaaaat cagtgtagga cttattggga tagcagctct aggattattg
     7321 ggagcttgct ccagcactaa tgatgcaaaa gtatcgaatg ataaagatgg aaaattagaa
     7381 attgtaacaa cattctatcc aatgtatgat ttcaccaaaa acatcgtcgg cgatgaagcg
     7441 aacgtggatt taatggttcc agcgggatca gaacctcatg actatgagcc ctcagctaag
     7501 gatatggcaa aagctcatga tgctgatgtt tttgtatatc ataacgaaaa catggaatca
     7561 tgggtaccaa aagctaaaga aagttggaag aaagctgggc ctaatgtagt agaaggaaca
     7621 aaagacatga ttttattgcc aggtagtgaa gaagaagatc atgatcacgg agaagaagat
     7681 caccatcatg aactagatcc tcatacgtgg gtttcaccca aaatggcaat taaggaagtt
     7741 tcaaatatca aggatcagtt agttaaattg tatccgaaaa aagcaaaagt atttgagaca
     7801 aatgctgaaa agtatttgac taaactgaaa cggttggatg ctgactatac cactagtctt
     7861 aaagaagcga aacaaaaaag ttttgtgacg caacacgcag cctttggata tttagctttg
     7921 gattatggat tgaaacaagt tcctattgct ggactaagtc ctgaagaaga gccatcttct
     7981 ggtcgattag ctgaattaaa agagtatgtt aaaaaaaata agatcaatta tatttacttt
     8041 gaaaagaatg ctaatgataa aattgcaaaa actttggcca acgaagctgg gataaaattg
     8101 gaagtactga atcctcttga aagtcttaca aaagaacaaa tggataatgg tgaagattat
     8161 gtttcagtaa tggaagacaa tctaaaagcg ttagaaaaaa caactatggt tgctggtgaa
     8221 gaggtagttc cagaaaaaga agcgaaggat gaaaagacag ttgctaatgg gtactttaaa
     8281 gatgccgatg tgaaggatcg cgaattgagt gattatacag gcgaatggca atctgtttat
     8341 ccgttgttaa aagatggaat tttggatgaa gttttcgatt acaaagcaaa aatcaataaa
     8401 gacatgacag ctgccgagta caaagattat tatactactg gctataagac agatattgat
     8461 actatcaaca ttaaagacaa caccattgat tttgtagtca acggtgaaca tcatcaatac
     8521 acatacaaat atgttggata caaaattttg aattatgaaa aaggaaaccg tggtgttcgt
     8581 tttaattttg aaactgatga tgcaggtgct ggtcgtttta aatatattca atttagtgat
     8641 catggaattg caccaagtaa ggcagagcat ttccatattt tctttggtgg agaaagtcaa
     8701 gaaaaactct ataatgaatt gcataattgg cctactttct atccagcttc attgtctaaa
     8761 catgaaattg ctcaagaaat gatggctcat taaaattcaa tttttggagg aaatacatgg
     8821 taagaaaagt attattgtct atggattcca agaatattga tgcttatcgg cgttatcgat
     8881 ttgcaaagca aatgagatta aatgggagta cattagctga tattgctgca actttacatg
     8941 ttagtattga cacagttcat agagtattaa aacgggatcc tgattgttgt tttatcaagg
     9001 tcaatactgg aagaagtaga cgtttagcaa aacggcataa tagcttggcc aattaattga
     9061 taataccaga gtagatcatt tttcccttat ttggatttga tctgcttttt attatgtctt
     9121 gaattgtcaa atcaagcgca acactttatc aaagaagact tcataaggtg ttctccaatc
     9181 taaacacttt ctaggtctgt tattcagttt ttcaatcatc tgatttatcg ttgagttatc
     9241 taccgtagct atctctttcg attttggcaa gtattctcga atgagtctat tcgtatttta
     9301 atttgttcat tgttgccaag ggcatgagga tctggaaaat aaaagggcat attattcaat
     9361 gcttctgtaa ctgcgaaatg attggagaat tcttttcctc tatctggagt gatcgttttg
     9421 accgcctcat ttggaatact gcttaaaagt tcaatcattt tctcgctcac ataagcggct
     9481 ttctttctgg ggaccttctt tcctgctaaa aggaagcatg attttctgtc tgtcaaagtc
     9541 actaaacaag taccaccagt tttgccagct acaatatcgg ctttccaatg accaaaatca
     9601 cttctatcat ctgcggattt tggacggcca tggatcgaat gagtaaggca aatctttcca
     9661 cgagactcga catgattttt tgtatgtctt gtttttcctc gatggtgcaa tgaacggatc
     9721 aggcctttat tgccgtgtga gaggggttct gtatcgaaaa gatcattgca aattgcacgt
     9781 tagatcgtga taaaactaat tgaaaagtcc atatgttcat gcttcaaacg attcgagatt
     9841 tcctctggcg accactgaaa atcgacaaat aaatgacgaa caattgacca aactcacgga
     9901 tcatttagaa tgtgataacg tccgcatttt tttcttcgat aagcataatt tttttccgct
     9961 ttggaaggtg aatagttttt ttcttgtttc ttctcagttc atgtaaaata gtaaacgggc
    10021 tatgctgaat gtcgttgcca attatactaa tagaaaatcc ttcttcgtga agcagaaaga
    10081 ttctttctcg ttcgagtata gtaagatgac gatactggct cataattatt ttccttctag
    10141 gagtgttctc gacaaactta tactagttgg atatcgatta tgactcattt ttatgtgttg
    10201 cacttaaagt gtaaattcaa ggtatagaaa gaggttccct atgaaaaaaa tacctattac
    10261 aatcttaact ggctatcttg gttcaggaaa aacgatactt ctaaatcata ttctgtacgg
    10321 tgatcacgga aaggaaattg ctgtcattgt aaatgacata ggggaagtaa atgttgatgg
    10381 ggtattagtc gacaagaaag gttttaaaag aactggagaa aaacttgttt cgatgccgaa
    10441 tggatgcatt tgttgtacat tacgcgaaga tttgattgtt gaactagatc aattagtgca
    10501 attttctgac ttgaatcaaa ttgttattga agcttcagga atcagcaaac caattccaat
    10561 tattcaagca attatattag ctaaaaaccc tttagacatt gatttgaccc aacgattaga
    10621 gattggtgcc attattatag tagtggatgt aaaacgtttt tgggataatt tcgaaacggg
    10681 tgaaaagatt caggaaagaa aagctgaagg taatgtagtt gaagaagaac aggatattcg
    10741 tggcttgtta attgatcaat tcgagtgttg taacatatta cttttaaata atagtgactt
    10801 agtgtcaacc aagacgattt acaaaattaa cggtctaatt gctaagttac agtccaatgc
    10861 caaaataatt aggacaatta aaggtgaagt agacttatcg aaaattctaa atacaaatct
    10921 ttttaatata gatgagactt cctattcagt gggctggttc aaagagttag agcttggcta
    10981 tcaaaatcat attcctgaaa cagaagaata tggtatctca agttttatct atcgaaatcg
    11041 gttactcctt gacgcacaaa aatttgccca tcttacggat aaaaattttc ctggcaatat
    11101 tacaagagca aaagggtttc tttggtttgc ccaacatagt gatttttcga cgatctttga
    11161 aacatcgggt agctataaaa gtattgaatc attaaattat tgggtagcta gtttacctaa
    11221 aattgagtgt caaatgatta tacaaaaaaa tcccgaattg aaggaagcct ggcatccgtt
    11281 gtttggtgaa cgcattaata aactagtttt tattggtatg aagatggatc aacaatgtat
    11341 taaggaacaa cttgagggtt gtttaactga ttctcttaat gcagataatt tccgaaaaat
    11401 ttcaccattt ccatggaaaa agtctaatat gtttagccag atatcgttaa tgaaattttt
    11461 aagaaaagct ggtgtcaaga taggcgatgt cataattatt ggcattttga ttattacctc
    11521 ttttattccc ttatttgtat tctctataga aaaggagaat gaaacaactg aagatgctat
    11581 caaatatgcc atcgttcgaa ttgatggcaa ggaaatggat cgcttcgatt tggataagat
    11641 caatcataaa ctcgtgaatt atcatcctgc gaagggacaa tataatattg ttgagattaa
    11701 agatggaaga attcgagtta aagaagataa tagtcctgat caaatcgcgg ttagaactgg
    11761 atggatctca aaacccggtc aaacgagtat ttgtttaccc cataagttag ttattagtat
    11821 tgagaaaaaa gaaagcacag attactacat ttactaatct ggaaatagat gaggaggttt
    11881 ttaataagaa aaagatatta ttattaataa tagcaggggc tttattaagt gtgttaagcg
    11941 cttgtggaca agaaaaagaa gcggtgacaa caggcacaag tatctttaac gggacctgca
    12001 atggtttagt taacagtcgg ttagattact tattttggct cttcgtcaat gagtgttggt
    12061 gaagaaattc aatagaataa tcgagatact cacacggcta gacagctatc ttgtctagcc
    12121 gtgttgttgt tctggcttta gtcagttggg tagtattctt agttttctta aaatattttc
    12181 ctcgatataa aaagattcgt tctcggtagt tttgaaagtt tctatagcca taggcaattc
    12241 gttttagtac tttgatatgg ttattcaaac attctatagg gccgttggaa tagggaacgc
    12301 gcaacgctcg tttgatttct gtttggtatt tcttgaaggt cgtgaacact ggttggtagt
    12361 gctctggcaa ctccttgtag tcttctttta ggagcgcgac gaattcagga acatcttgtc
    12421 ttctgataac ggaaagaaaa tcctggtaga cttcgtagcc tcgctttaag gaatcatcat
    12481 aagataatag ccgatcgact atctctgctt ctgtcagatg atctcgaaat gacggacgcc
    12541 agtagcgatg ctgacctttc aattcccacg cattcttttg aagtagtttc cagtatttct
    12601 ttaagtgctt cgaccgacga tccccttttt taaaggtctt cattacttga attcggtggt
    12661 tggtaaaagc ccgaccaatg tgttggctaa tatgaaagcg atcggcgacg attcgggcat
    12721 tcggaaaaca ctctttcacc aatgtgcgat agggtgtata gaaatctgaa accactagac
    12781 gcacttgttc acggactttt atagggtagc gcaagaaata gtcgcgtaaa ggattgagtt
    12841 gccgattttc cacaatatca atcagttgat gggtcttgcc gtccatcatg acaaagctca
    12901 tggctcccga gacatttttc actgatttga attcatcgaa acacaccact tctggtaaca
    12961 gctggctcaa agaaatggtt ttaggccgaa ggctgcgaag tattcgaatg acagtggtcg
    13021 gagaaatgtg cttcatacgt gcgatcaaag acatagaaag aggttcgctt aatagctcaa
    13081 gaatggcttg tttgactctg cgagcaatgg agcagcgacg atcactaact gaatcttctg
    13141 ctaaaaaagt ctttccacag tgtttacatt tgaagcgctg tttgttaatc cgcagaatgg
    13201 tcttgtagtt actgacatca ttcaataaga tggatacttt tttccagccc tatttaatga
    13261 tcgtttgttc attttgatag tggcgatgaa agcattcctc cggttgatag gtcaatgtgc
    13321 catcaaaaac aaaacatgtt tcgtcattga ttcgctcttt gcgaaaggca tcttcatgaa
    13381 agataagatt taggtctaga atatctagta actctttggt aaactctgaa taggacatct
    13441 tgaaacactc ctttgaatgg ttttcgtcga ctttattcta aaggatttta aggtgtctgt
    13501 ttgcgtttat tagaaaaaag aaaaagtatt ggcaacagaa ggcgtcacca acactagata
    13561 ttatagatcc cttattttct tcgcttcaaa ttgtcaagga gtcatcataa attttgtatg
    13621 gattcttttg tttgggtagt agtcttctaa ataatcttgg attaacacct tcatctctat
    13681 tttactttta tatttgttgg agtcgattaa ttctcatttg attgatcgat gaaacgcttc
    13741 aattactgca ttgtcaacag gagtcccagt ttggctcact gaatgtgtga tgtggtggtc
    13801 gttcaacagc tcttgataaa taaaagaccg atgctggcta cctctatcgg aatgaattac
    13861 cgtaggcaat tctccttaat aaatttgtaa tggacggacg acaatctctt ttttcatgtg
    13921 tgaatctacc atatagtaac gtagaatacg agttgctaag tcaatatagg tggacaaata
    13981 gaggcgaccg tcattacatg gaatgtaagt aatatccatc acccaaacag catcaatttg
    14041 gttctgttca aattatcgat tcaacatttt tttaccattt ctttgattgt tttttctcta
    14101 ccatgagaag atttgcgtcg atgaaatcct cttgtgcata aattcatttc acgcataaga
    14161 acagctacaa cacgtttatt gatttcgatt ccttcatcgt aaagtttttg agtgatccct
    14221 ggagatccgt atcgatcttt gtgttcgtag aacactcgtc ttcctctttt agtcgtttat
    14281 tttcctgttc aagaatgtag aaatctgctt tatcaggtaa tctttttcct tgtccagcaa
    14341 aagcattttt cccgtatcga cgatattctg aaacccatcg ggaaattgtt ggacgagaga
    14401 tattgtattc ttcagcaatt ttcttggtag ttactttttt ctcaaggata tcctgtgaaa
    14461 tctttagttt aaatttacga tcatatgttt ttctcaatag agttcattcc ttccggtaac
    14521 gtaactgata gtcaagaaaa gtgtatcata gcccaactta gtatcagggt ttgtcaacta
    14581 aactgtggaa gttgatagat aagagttttt aacaaccaaa attctcttga ctatttttga
    14641 aatcagacaa attttgattg gacacatagt tgaataaatc taccgtcgtt acggaaggta
    14701 aatcgcatgc ttttcaattc tagaggagaa gtcctcgttg aagtaccata gcccagttct
    14761 ggattcgacc tcctgcccac ttcatacgta aataaagtaa ttttaggagt gagactgtga
    14821 caaaagttat ttttaagcta aaaacgaatt aaaaaacgtt gataattaaa atcattcgtt
    14881 ttagattcta tgaatcatta tagaacgctg taaaatcgat actttataat tataaagaag
    14941 atagtttcaa atttattgtt cgaaatttga aactatcttt ttacttatgt cacagactcc
    15001 cttagttgag ttattcttta atttcgaatt tcgagatagc tagatatatt gcaagcatac
    15061 attcttgata acaatcttga tcatattttc cagttctcca ggattgctta tgaatcaaag
    15121 agctaaatct tttgagaatt gcctcaacag cttcttcatt tccagccttt gctaaaatga
    15181 aatcttcttt taaagaattc ataaatctac cttcttccca tggacttata atctatttct
    15241 ttgggaagga ggagaacgag caaagaagca tacaaaatta gttattatgc agatattaaa
    15301 ccagcatttt ttgaattttt ttgtaaagtc gatgttttaa atttgtcgca ccctgtcttg
    15361 taatccccag aacctttcca atttctttat cagttttatc aaagataaat ttttcgataa
    15421 gaaaaatttg ttcaggttct ttcaacaaag gaaggatttt tgctaatttt atatcttcaa
    15481 caaggagagt cacatttaaa acattaatcg gttgtttaaa ttttatagta tctttagtaa
    15541 acaaatatgg tgggagttga tcaagttgtt catgtttttg aatttcttct tgttttttat
    15601 aataagtatt agcggtgttc aaaatgacct tttcaaagaa tcgaatcaac tgggcattta
    15661 cgcgttcgtc gttatctgac atattgcaca cctcctccat taagatttaa agggaaaaga
    15721 ggcaaaaaac acgaaaagaa gctaatgcaa ttatgctgcg ctgcgaataa cttctataag
    15781 ctcacatgca ttgataggac tgctgatgtt tattttcaaa aatgtttttt tagttgataa
    15841 tggatagtta tctttatact tagaaaagaa aattcatata tcttcttaaa tatcaaacat
    15901 gtccttatgg ctaagaaaat gtcttgagct ttttacgtat aataaatctt ttctaaaacc
    15961 tccttttgga taatattctt attcgtgtat agattgtatt ttttatttct tcccccttca
    16021 taattaacaa ctagaaaaga gttcgaatag acacgtattt gaacgaaaat ttttattgga
    16081 ttcccaaatt ggaatattta gaaacgaaaa attcctatta tctgtatagt gcttagataa
    16141 taacggatca taataattat tgtctttgaa ctagatatat gtaaatagta ttcatcatga
    16201 tgaaaaatga tgagttctcg gtgataaaat gtacttttta cggtggaata tacatgaaag
    16261 cgataagtgg atattttata atgaagtaag ttagcttatt ttgacagagg aatagtattt
    16321 tagataacgt ataaaatact atttaatgat gtagaaagga aagagagaaa caaaagtgtt
    16381 ttcagataaa gaagtcttat taaagtctct tcatgtttgt ttaaagttac ctatcgtggt
    16441 ttt
//
LOCUS       DBGZHO010000058        16050 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.061, whole genome shotgun sequence.
ACCESSION   DBGZHO010000058 DBGZHO010000000
VERSION     DBGZHO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.061"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            172..516
                     /locus_tag="ACN3HL_002173"
     CDS             172..516
                     /locus_tag="ACN3HL_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HHC8007005.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="ACN3HL_002174"
     CDS             517..936
                     /locus_tag="ACN3HL_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HHC8007006.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="ACN3HL_002175"
     CDS             complement(1028..1378)
                     /locus_tag="ACN3HL_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007007.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="ACN3HL_002176"
     CDS             complement(1344..2675)
                     /locus_tag="ACN3HL_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HHC8007008.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="ACN3HL_002177"
     CDS             2930..3496
                     /locus_tag="ACN3HL_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8007009.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="ACN3HL_002178"
     tRNA            3641..3728
                     /locus_tag="ACN3HL_002178"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4064..5038
                     /gene="bsh"
                     /locus_tag="ACN3HL_002179"
     CDS             4064..5038
                     /gene="bsh"
                     /locus_tag="ACN3HL_002179"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HHC8007010.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            5363..7258
                     /gene="asnB"
                     /locus_tag="ACN3HL_002180"
     CDS             5363..7258
                     /gene="asnB"
                     /locus_tag="ACN3HL_002180"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HHC8007011.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7453..7899)
                     /locus_tag="ACN3HL_002181"
     CDS             complement(7453..7899)
                     /locus_tag="ACN3HL_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HHC8007012.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8127..8276
                     /gene="rpmG"
                     /locus_tag="ACN3HL_002182"
     CDS             8127..8276
                     /gene="rpmG"
                     /locus_tag="ACN3HL_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HHC8007013.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8364..8882
                     /locus_tag="ACN3HL_002183"
     CDS             8364..8882
                     /locus_tag="ACN3HL_002183"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HHC8007014.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8959..9915)
                     /locus_tag="ACN3HL_002184"
     CDS             complement(8959..9915)
                     /locus_tag="ACN3HL_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HHC8007015.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10081..10887
                     /locus_tag="ACN3HL_002185"
     CDS             10081..10887
                     /locus_tag="ACN3HL_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007016.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10884..11873
                     /locus_tag="ACN3HL_002186"
     CDS             10884..11873
                     /locus_tag="ACN3HL_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHC8007017.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11870..12874
                     /locus_tag="ACN3HL_002187"
     CDS             11870..12874
                     /locus_tag="ACN3HL_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HHC8007018.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13006..13548
                     /locus_tag="ACN3HL_002188"
     CDS             13006..13548
                     /locus_tag="ACN3HL_002188"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HHC8007019.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13568..14266
                     /locus_tag="ACN3HL_002189"
     CDS             13568..14266
                     /locus_tag="ACN3HL_002189"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HHC8007020.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14287..14499
                     /locus_tag="ACN3HL_002190"
     CDS             14287..14499
                     /locus_tag="ACN3HL_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HHC8007021.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14499..15461
                     /locus_tag="ACN3HL_002191"
     CDS             14499..15461
                     /locus_tag="ACN3HL_002191"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HHC8007022.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15479..15874
                     /locus_tag="ACN3HL_002192"
     CDS             15479..15874
                     /locus_tag="ACN3HL_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HHC8007023.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
BASE COUNT         5142 a         2702 c         3308 g         4898 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattaaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg tagaatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga tgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc atacagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagcacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcaagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cccatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc gaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtataccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataata cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaaa cacctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttgg ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc cttttttttg ataaaaaaaa atactagatg
     4021 taagataaaa gtgtaaaaac gatttgtttt aggagggaaa acgatgtgta ccgcaatcac
     4081 ttatgcaacg aaagaccatt attttggaag gaattttgat tatgagatgt cttataatga
     4141 agtagtcact attactccaa gaaattatcg tttcgatttt agaaaggtaa aaaatttaga
     4201 taaacattat gcaatgatag gaatagcagc tggggtatcc aactatccac tctattatga
     4261 ggctacaaat gaaaaagggt tgagtatggc aggactgaat tttcctggca atgctgatta
     4321 taaagaatta caagaaggaa aagataacgt tgcaccattt gagtttattc catggatact
     4381 agggcaatgc tcaaccatag acgaagctaa agaattattg gctactatca atctagtcaa
     4441 tatcgatttt agtgaaaaac tacccttgtc acctttacac tggttattag ctgataaaga
     4501 aaaatcgata gtaattgaaa gtatgaaaga tggacttcat ttatatgata atcctgtcgg
     4561 tgtgttgaca aataatccgc catttgatta tcaattattt aatctgaaca attatcgctc
     4621 gctatcaaat ggaacaccag aaaatcattt ttcaaaccag atcagcttga atgtttatag
     4681 tcgtgggatg ggaggattgg gcttacctgg agatctctct tctgtttctc gatttgtaaa
     4741 agccacattt actaaaatga atgctgcatc aggtgattca gaatctgaaa gtatcagtca
     4801 attttttcat atactaggct cagtcgagca acaaaaagga gtatgcgata ctggagaagg
     4861 aaaatacgaa tatacgattt attcttcttg ctgtaacgtt gataaaggga tttattatta
     4921 tcgtacgtat gaagacagtc aaattactgc tgtaaatata aataaagaag acttggatcg
     4981 tcatgaattg gtcagttatc cagtcataaa agagcaacag ataaactatg tcaattaatt
     5041 aatgaataga tccgtttggt atcatatttt ctgatacagt cataattaga cacgatcttt
     5101 aggtcgtgtc tttttttgct gttttttttg gaaatagcat ccactaatat ttttttaaca
     5161 cgaagagaat aaggtagcct caaaaaagaa aacatggtaa attagatatt gggactttat
     5221 tttctgtaaa aacagaaact ttcatctttt gttttcacgt gacgaaattg taagagagaa
     5281 aatattcgtc cgctatttat tctatgataa gatgcatatg aatgaaataa acagtaattt
     5341 tatattagga tgtgaaagtt aaatgtgcgg tattgtaggt tttgttaacg acaaggacaa
     5401 caaaaaaaca attattaata caatgatgga tcgaatcgtt caccgtggac ctaatagttc
     5461 aggagaatat atcgataaac atgttgcttt aggattcaga agattaagta ttattgactt
     5521 agagggcggt actcagccta tttacaatga agatcggaca aagatcatta tttttaatgg
     5581 cgaaatctat aattaccagc ctttgagaga agaattgatt gcagctggcc acgtttttca
     5641 aacacatgca gatacagaag tccttttgca tggttacgaa gaatggggaa cagaattatt
     5701 gcaaaagatc cgcggaatgt ttgcttttgc tatttgggat aatgaaaaga atgagttatt
     5761 cggtgcaaga gaccactttg ggatcaaacc atattattat gcagaaatga acggaacatt
     5821 tatgtttggt tcagaaatca aaagttttct gcctcatcct gattttaaca aagaattgaa
     5881 caaagaagcg ttgaaacctt atatgacttt ccaatattct ccattaaacg gcgaaacatt
     5941 cttcaaagat gtctatcgtt tgcctgaagg ccattattat acgtataaag atggaaaact
     6001 agacattcag caatattggg atgcagattt tgaaacaaaa gaaacgcatt cccgacaaga
     6061 atggatcgaa aaaatcgacg aaaccgttca agcttctatt gaagcacata cggtcagtga
     6121 tgtagaagtt ggttctttct tatccagcgg ggttgattcc agttatgtaa cctctgtatt
     6181 gaaaccagat cattctttct caatcgggtt tgatgataaa acctataatg aagcgattga
     6241 agccagaaaa ctaaccgaac tattggactt agataataca gcagcagtga tcgacggaga
     6301 catgtcgttc aaagcattcc ctttgatcca gtatcactta gatgaacctg attcaaatcc
     6361 ttcttgcgta cctttgtact ttttagcaaa tcttgcttca caaagtgtgc gggtagtcca
     6421 atctggagaa ggggcggatg aactgtttgc gggataccaa acgtatggat tccatacgaa
     6481 ttcaaaattc atccgtgtga ttgctcaagg attgaaaaaa ttaccaaaag gaacacgcta
     6541 taatttagga cgtaaaatcg gaaaaatgaa aaatttccat ggacggatcc atttatatga
     6601 atcacttgct cctgcaaaag aatattttat cggtcatgct cgagtgttcg aagaatcaga
     6661 agcatcagaa gtgttaacac caaaatatca aacagcacca tctgtggatg aaatcatgac
     6721 tgttcattac gagaaaacag aaggaatcaa agatgaagtc aataagatgc aatatgtcga
     6781 tcttcatcaa tggatgccaa aagatatctt gttaaaggca gataaacttt ctatggcaag
     6841 ttctttggaa gtccgagtac ctttattgga tatcgaagtc atgaaattgg ctcaacaaat
     6901 accaagtaag tttttattga atcaaaacaa cacaaaagat attttcagac aagctgcgaa
     6961 caaacatctt ccggaagaat ggtcgaatcg tgtgaaatta ggattccctg tgccaatcaa
     7021 agcttggttg aaagaagaac acggctacga acaagtcaaa gcattattcg aagcagattt
     7081 tgcaaaagaa ttttttgatc aagaaaaaat catgaagttg ctagatgacc atcacgaagg
     7141 acgtaaagaa gagcaaagaa aaatctggac aatcttcagt ttcttgacat ggtataaagt
     7201 ctactttgta gatgaaacga ttccgcaagc agaagcaatc gactatgtga ctgtttgatg
     7261 aaaatcaaat atcaataaaa aagaggtttt ctcctaccgt ttaacactga gtgataagaa
     7321 acaatttcaa aaaacagctc ttcccgtttt atagatatta tgacttatgg ttcggagttg
     7381 gcagaggaac accattgttt cgaacataag ggggttgtga cacgattttc gtcacaaccc
     7441 ctttacatat gttcaataat cgatttcttt ttcttttgtc ccatcttttt tataaatgaa
     7501 caaagttgat tctttgtttt gtgctacttg ctttcctttt tcgattgctt ctttttttgt
     7561 atcaaaatgg ttgcttgcct tttttgcccc tttagatttc acgatccatt gttcttcctc
     7621 atattctacg atcacatctg aatcaagcag ttttccagca cgaggattcg tatcgtgttc
     7681 atccgtcttg cttggatttt tttctttttc gaaagttcgt ttttctgatt cactagcatc
     7741 ttcataccat ttttttgctt gatcaatggc aattgggatc gcacggttat cagggtaccc
     7801 ttcatctaat aatgcatttg cgatgtcgat tgcttttttt cttgtcaatt tatctaagtt
     7861 tttcattgat gcaggaaagt ccttcatgtt ccatggcata ttagtatccc cctttattaa
     7921 aaaacataat ctatataaac aagtgtaagg gtatttatac aaaaagaaaa agattttgtt
     7981 tgagaagtaa aaccgttgta tttatcgtca agtagtttta cttaacaaaa tcgtgaaaaa
     8041 cactagcaat ctagaaaaaa tcatggtaag ataatcaagt ctgagagtca tcttagagga
     8101 ttcttgtaaa aatgggaggg aaaaacatgc gcgtaaacat cactttagag tgtacttctt
     8161 gtaaagaacg taactatcta acaagcaaaa acaaacgtaa caatcctgat cgtttggaaa
     8221 aacaaaaata ttgcccacgc gaacgcaaag ttactttgca ccgtgaaaca aaataatgtt
     8281 tttaaagttc tcaattcctt gctggtcaaa gaattgagac tttttttatc tcaaaacatc
     8341 taaaatcata aggagcggat aatatgttta tttccatgtg ggcacaagat aaaaatggtc
     8401 tgatcggcaa aaatggtttg ttaccatggc gattgccaaa tgatatgcgt ttctttcgcg
     8461 aacatacaat ggatcgaatt ttagtgatgg gaagaaagac ctatgaagga atgggggatc
     8521 tttcacttcc ttatcgccat atcatcgtgt tgacaacgca accaaatttt cgcacgaaag
     8581 aaaatgcgga agtaatgcat tcgatcgatg aacttttgtc gtatagtcaa acgatctcag
     8641 aagatatcta tgtttcgggt ggtagtcgga tttttcaaga acttcttcct tacactggtc
     8701 ggatctggcg aacattgatc gatagcacgt ttgaaggcga tacgtatatt gggaatattg
     8761 atttttcaga cttcgccctt atagaggagt atgaggggat aacggatcaa gaaaatctat
     8821 atgcccatcg ttttcaaaaa tgggaaagag taaaaaatag ggttgcttca aaagaagaat
     8881 aaaatctatg cgtctagttt gttaataaga aaaaaagcat ctcacgacta atcgtgaaga
     8941 ttcttttttt agttaaaatc aatttagttt ttctttgata tcattgacca tttcctgact
     9001 ggcaataggt ccgttatata gccaactaga ttcaggtccg aattgcagta catgattgtc
     9061 tgtcactgct ttaagattct tccagcttgg ttcattgaac atggcagcat ctttgtcact
     9121 gttcacaagg atgatgtagt cagcatctaa ttcagctagc ttttcagagg aaacagcaga
     9181 ccagtcagaa gtggcttttt tggagacctc ttccactaga tcaggaacac caaattccag
     9241 atcgtcgtat acgattcttc cacttgaccg atttttgctg accataaagg ctgagttgtt
     9301 ggtcacccac aacactgcag ctgtcttgtt ctcgatttta tctgctagtt cttctcgagt
     9361 tttcttgatg gatttttgat aatcggaaat gattttttct gcctcttttt cttttgccaa
     9421 agctttgccg acatctttta gttgttcttc ccatgtgaca tctgttccgt tttttacaac
     9481 ataagttggc gcgattttgc tatattgttc gtatttcccg ccttcgacag tagcggaaga
     9541 agaaatcaac agcaaatcag gctcaaagct taacactttc tcataaggaa ggtcataaga
     9601 aatcgttggg acatccttta aatcatcttg cagataatct tgaatggaac cactgccaac
     9661 agtccactgg gcgataggtt tttcccctag tgcaatcaga tagtcttcta agtaactgcc
     9721 gatgatccgt ttgggcgcgt ttggaatctc tactttatgt ccaagtgtat ctgtgactgt
     9781 atgagtacta ttggatgaag tcgtcgaatt ggcagttgta gctgtttctt tatctgaaga
     9841 gggggagcaa gcgctcagta ctccagccag cagcaatatg ctagataatg tgaatacttt
     9901 tgtttttaat ttcatttctt tcctcctaac ataattgaga atctttctca ttggttatta
     9961 ttcctgatat ttcgaacgct gtcaaccgct tcatttggct atagatatga aagtagcgct
    10021 tgacgaaatg ttgaaacagc gtcataattg agaatgattt tcagcgaaag gatgggtgaa
    10081 atgacgagat taagagcagc tgacattgca gccggctacg aaaacaaaaa aatcattgaa
    10141 aacatgtctg ttacgattcc tgaagggaaa atcactagtt tgattgggcc aaatggaagt
    10201 ggaaaatcta ctttattgaa aagttttacc cgtatactac ctgtgaaatc aggaaagatc
    10261 attgtcaata actctgatat ctctacatac agttcaaaag aacttgcaaa aaaaattaca
    10321 ttattagcac aaactagtga acaccctaca ggtatgacag tagaagaagt agtatcttac
    10381 ggacgatacc cttatcaaaa actgttcagt ggcatggaca cgcaagatca tgaagcaatc
    10441 gagtgggcgt tggatgctac aggtctagct ggatttcgta tgcgggatat cgcaacgctg
    10501 tctggtggac aaacccagcg tgtctggatc gctatggcgc ttgctcagga aacagatatc
    10561 ttgatcttgg atgaaccgac aacattttta gatccggcac accaattaga gatcctacag
    10621 ttattgactg aaatcaatca aatgaaacaa acaacgatct tgatgtcgat tcatgacatt
    10681 aatcatgctt cacgtttttc agattattta ttagcaatga aaaacggtaa gttgatcaca
    10741 gaaggtacac ctgaagaagt gatcacaaaa gagtgtatga aaaaaatatt tgagattgat
    10801 gcaacgattg tcacgcttcc aagaacaaat aaaccagttt ttctaaccta tgatttgttg
    10861 ccaaaagagc aggaggatca attatgagga ctatgaagaa aaatagactc ctgcttttgg
    10921 tctgttttgt tcttttgatt attttttttg ttgctctttc aaatggcgca gcgactgtgg
    10981 gaaaagcaga tttttggcag gcgttgtttg attttgatag atcaaaacaa agtcaccaaa
    11041 tcatacgaaa tattcgtttg cctcgtgtgg cgggagcatt tcttgtaggg agttgttttg
    11101 cattgagcgg tgcattgatg caaggagtga caagaaatcc tttagcagat tcaggcttac
    11161 taggaatcaa cgcgggtgct tcgttggcaa tggcccttag ttttgctttt tggcctaaag
    11221 cttctgattt ttctgtgttt ctaatgtcat tggcaggttc ttttgctgta actttgctcg
    11281 tatttggttt tttgcagttt tcgaaaatgg gcatgaatcc tttacagctg attttagctg
    11341 gcgtagctat tagttctttt tttactgcta tcagccaagc acttacccaa ttctttaatc
    11401 tgcagcagga tcttgctttt tggtttgtag gcggagctgc caatatcaca tggaaacaat
    11461 tagcagtatt gtttccttta tatatacttg ctgttttggt ttctttttca ttaggaaaag
    11521 caatatcttt gattcatttg agtgaaacac atgcattagc tcttggaagt catcctaaac
    11581 gaacgcggtt gattgttttc tgtctagttg cagtgttagc agccattgcc gtttcgttag
    11641 tcggacctgt ttcatttatt gggctgttgg ttccgccagt tgttcgcgga atggttggaa
    11701 cggactatcg ttatgttcta cctgtctctt ttttagttgg cggtggattg gttatgttgg
    11761 cggattttac agcgaggatg atcaatcccc cttttgaaac accttttgga ttagtcattg
    11821 cattgattgg cgttccgttt ttactgatac aagtaaggag ggaacaacgg tgaaaaaaat
    11881 atattggacg ttctatttct tgctttttgt acttgtcatc ctgtctatag gtagtttaat
    11941 gattggtacg ccttttattt acctggatca gctttttgcc acgttcatag ggaaagaatc
    12001 atcttctttg gcgctgattg ttagagaatt tcgagttcct cgattactga tcagtttatt
    12061 agcaggagct tgtcttggcg tttctggtta tatcttgcaa ggagtaacaa gaaatgaatt
    12121 ggcagattct agtatattgg gcattaatgc cggagcagga tttttagtga tgctttattt
    12181 aggtttcttt tcgcactatt cgctgccgtt tctattgcta gttgtagcct ttctaggtgg
    12241 tgttttagct gcttgctgtg tctatcttgc ggcctatgat cgaaatggct ttttgggtat
    12301 gaatcgaatc ttattgtccg gtattgccgt taatgccggc ctttctgcat taacattgct
    12361 atgcacgatc caattatcta aggaaaatta tggatttgtg aatgcatggt tagcgggatc
    12421 aatctggggt gcgagctggc cttatgtttg ggcattgctt ccatgggcgg ttatcttaat
    12481 tccgctagga ggactttatg cacagaggat tggattgcta tcatttggtc aagaacgcgc
    12541 gcaaggatta ggccttaacg tggctaaaag tcaaaaaatc cttttgttgt tagctgttgc
    12601 tttggcaagc ggtagtgtag cggtgacagg tagtttatct tttgtaggac tactagctcc
    12661 tcatgctgcg aagctagtcg tacgtaaaga aaataactgg acctttgttc tgagcggttt
    12721 gttcggttcc atttttctgc ttagtgcaga tatggttgct agagtgattc taccaagtgg
    12781 ggaagtacct acaggaattt tgattgccct ttttggtgcg ccatattttc tgtatgcact
    12841 ttttatcaga caaaaacacg cgctgaacag ttgaaattta ttaaaaaagg aaggccaatc
    12901 atttctaggt cttcttttta ttctatttat gcatttattt gaaagttcga ttgctatttt
    12961 tctttttttc ctataccatt ttatgagaga aggaagggtg agtttttgga ccaattgaaa
    13021 gtaagattac gccggaaagg aatcgaaaag ctgaaaaatc tggccaaaag tggcaagaaa
    13081 aaggaaaaag aacagcgaat ctataaacag ctattcgcca gcgagtactg gaagtcagca
    13141 aaagtgatag ggacgacttt atcgaatgaa tttgaactgg atacacagcc ggttatccaa
    13201 cgagcagaaa aagaacaaaa gaaaatagtt gtacctaaaa ctttgccgaa acgtcagatg
    13261 gcgttttatg aaatggatga acagtccgtt cttgtacgtt cgagttttgg tgttcttgag
    13321 ccacaatcag agaagctcta tttgccggag atgatcgatc tcctcattgt accaggtatt
    13381 atctacaata gagccggtta tcgaatcggt tttggcggtg gttattacga ccggtattta
    13441 aataattttc ataaaaaaac atgtagcctt gtttttcgtg aacaattgaa tgaacaatgg
    13501 caaccggaga gctttgatca gaagatccaa caattgttta ttgactaaaa tgaaatggga
    13561 ggttttcatg aattatcaac agcaaataaa attgcgtgca tggttaagac gaccgttatg
    13621 gacctatgct tttttaggga tacagacagc ggtcttcctc atgatggaat tatttccgcg
    13681 acttgagatc ccttattatg ccggaatgta tggtccttat cttgttcact tcaatgaatg
    13741 gtggcgttta gtgacaccaa tcttcatcca ttttggactg atgcatttcg taatgaactc
    13801 actgatactg tattttatgg ggcagcaaat cgaggcaatc tatggccatt ggcgtttttt
    13861 cttgatttat atgttcagcg ggataatggg aaatacagca agctttgctt ttaacgaagc
    13921 gaatgttctg tctggtggtg cgagtacttc gatattcggt ttgttcggtg cgttgtttat
    13981 cttagggttt cattttaaac ataacccagc gatccagcag ctagtcagac attttctttt
    14041 atttattgtg ttgacatttg tttttggtct tctggatacc tctgtagatg tttggggaca
    14101 tgtcggtggg ctaattggcg gattagtgtt agggaatgtt ttgggtctac cgaaacaaca
    14161 gacaagctat tcgatacacc aaaggattct ttctacacta gtttttgtat ttctttttgt
    14221 aatatgtatt ttactgggtt taaaaaaata tggtttactt gtataatatg aaggaagtgc
    14281 ttaaagatgg agagcttata tgatgtacag cagctgttca aaaaatttgg catctttatc
    14341 tatgtgggtg cacgcatcta tgacattgaa ttaatgacta tcgaattgcg taatctgtat
    14401 gatagccgtt tgattgatca tgatacatac atgacagcgt ggcgcatatt aaaaagagag
    14461 caccgaattg aagaaagccg aaagaaagga aatttgtaat ggacaagaag attattggga
    14521 ttgatttagg tggaacaaca gcaaaatttg caattttaac accagaagga gagattcaac
    14581 aaaaatggag catcgatacc aatattttgg atgatggtaa gcatatcgtt cctgaaatca
    14641 ttgaatcaat caaccatcgt ttgaatttat ataatatgaa agccgaagac tttatcggaa
    14701 tcggcatggg taccccagga agcgtggaca gcgaagctgg aacggttatt ggtgcgtata
    14761 acttaaactg gacagaagtt caatttgtga aaaaactgat cgaggcagga acaggaatca
    14821 aattcgctat cgataatgat gcgaatgttg ctgctttagg tgaacgatgg aaaggtgctg
    14881 gagaaaacga tccagacgtt gtattcgtta ctctaggaac aggtgttggc ggtggtatcg
    14941 ttgctggcgg aaatttgatt cacggcgtga gcggagcagg cggagagatc ggccatatca
    15001 ctgtggatcc tgaagggttc gaatgtactt gcggtaaacg cggatgttta gaaactgtgt
    15061 ctagcgctac tggtgtggta cgtctaggtc gttacttggc agaagaatac gcaggagatt
    15121 caaaactgaa agcaatgtta gacaacggtg aagaagtaac aagtaaagat atctttgaaa
    15181 tggctcaaga agacgatccg tttgcattga tggttgttga tcgcgtatgc ttctacttag
    15241 gtttagcttg cgccaacttg gggaatacat tgaatccgtc aagtattgtg ttaggtggag
    15301 gagtatcggc agcaggagaa tttttacgta gccgtgtaga gaaatatttt aaagaattta
    15361 ctttcccgca agtaagagaa tcaacaaaaa tcaaattagc agagcttggt aatgaagctg
    15421 gtgtcattgg tgctgcctca ttagccttga aatttgctta aaaaaacgga ggcattacat
    15481 ggttttatgg gtaattaata tcattttgct attgattgtg cttgcaatca tcttttggga
    15541 agtctatcta cgagtaatgg ccaagcgttc agcaacgact ttgacagaag aagaatttcg
    15601 agaaggaatg agaaaagcac aagtaatcga tgttcgcgaa aaagatgtgt ttgatgctgg
    15661 gcatatttta ggtgcaagaa acatccctta cactgttttg aaagattcat taggatctat
    15721 tcgaaaagac cagcctgtct atatttacga tcaaaagaaa agcttgagca tccgtacagc
    15781 aaataaatta cgtaaagcag gttatcaaga gatttattta cttaagggtg gatatgacgg
    15841 atggtctgga aaaatcaaaa gtaaaaaagt ataaaacaga tgattgtatg acagctttaa
    15901 aaaccgaatc aatcattaga ttttgaccaa gatcacatga acggcgcaat ggatagttgt
    15961 gccgttcatt ttttttattt tgtgctatta tctacatata taagctaagc gaaaaggcag
    16021 aaagaaggaa acaactatga tcaaattaaa
//
LOCUS       DBGZHO010000059        15936 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.062, whole genome shotgun sequence.
ACCESSION   DBGZHO010000059 DBGZHO010000000
VERSION     DBGZHO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.062"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(15..1154)
                     /locus_tag="ACN3HL_002193"
     CDS             complement(15..1154)
                     /locus_tag="ACN3HL_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HHC8007024.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACN3HL_002194"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACN3HL_002194"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HHC8007025.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACN3HL_002195"
     CDS             complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACN3HL_002195"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HHC8007026.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACN3HL_002196"
     CDS             complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACN3HL_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HHC8007027.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACN3HL_002197"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACN3HL_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HHC8007028.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7259)
                     /locus_tag="ACN3HL_002198"
     CDS             complement(6168..7259)
                     /locus_tag="ACN3HL_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HHC8007029.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACN3HL_002199"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACN3HL_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HHC8007030.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="ACN3HL_002200"
     tRNA            8802..8873
                     /locus_tag="ACN3HL_002200"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
     gene            complement(9065..9949)
                     /locus_tag="ACN3HL_002201"
     CDS             complement(9065..9949)
                     /locus_tag="ACN3HL_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HHC8007031.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(10036..10935)
                     /locus_tag="ACN3HL_002202"
     CDS             complement(10036..10935)
                     /locus_tag="ACN3HL_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HHC8007032.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(10952..11458)
                     /locus_tag="ACN3HL_002203"
     CDS             complement(10952..11458)
                     /locus_tag="ACN3HL_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HHC8007033.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(11647..12267)
                     /gene="rpoE"
                     /locus_tag="ACN3HL_002204"
     CDS             complement(11647..12267)
                     /gene="rpoE"
                     /locus_tag="ACN3HL_002204"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HHC8007034.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(12343..12780)
                     /locus_tag="ACN3HL_002205"
     CDS             complement(12343..12780)
                     /locus_tag="ACN3HL_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HHC8007035.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            12943..13773
                     /locus_tag="ACN3HL_002206"
     CDS             12943..13773
                     /locus_tag="ACN3HL_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HHC8007036.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            13757..15124
                     /locus_tag="ACN3HL_002207"
     CDS             13757..15124
                     /locus_tag="ACN3HL_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HHC8007037.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            15143..>15936
                     /gene="yidA"
                     /locus_tag="ACN3HL_002208"
     CDS             15143..>15936
                     /gene="yidA"
                     /locus_tag="ACN3HL_002208"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HHC8007038.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAI"
BASE COUNT         4310 a         3333 c         2938 g         5355 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgtccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag tttcgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc cgacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaaatctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaagaaaatt ggtggacagt tttttgttgt acctgtatag atattgttaa gcctttgcaa
     9001 gtaaggtagt tatgtgttca actacttatt aaaatgtgtt atttattaaa gatacttgtc
     9061 tcacttactg aactggccga tgatcgtttc tgccataata gttctcgaca gccgttggat
     9121 gccctaataa atccccaact gtcgtgatgc gatacccttg ctctttcaga taatcgatca
     9181 cttgaggaac ggcacgaatc gtttcaggat agatatcatg gaataaaata attgccccat
     9241 cgtatactgt tgcttggatc ttctgcaaaa tcaaatcagg atttcttgtc ttccaatctt
     9301 ctgaatcaac agaccattcg atgatcggtc gctggatgat cgttgctcct acattcgtga
     9361 cagaaccata gggcggacga acaaaagtgg gggttttgcc agtgactttt ttgatctcag
     9421 tgtctgcttt cgtcacttcc tccgtcatcg actgggcaga aagagtggcc agattctgat
     9481 gatcgtatgt gtaattgcca atctcgtgcc ctgcttcagc tgtctgcttc acgatttcag
     9541 gatgctgcgc cgtattttct cctaagacga aaaaagtggc atgcacgttt ttttctttta
     9601 agattcgcag aagctgcggt gttgtggtcg ctcctggtcc atcatcaaag ctgattgcga
     9661 cgcttttgac agccggatct cggctcgttt ttgtactgtc ttgtgttgat tgtgatgact
     9721 gactttgtac cttttccgct gattcttgaa tggcttcttt gacgttagct gtttcagttg
     9781 attggctttt aatggttgat tgttctgatt gtttgaaaga ttgtgacgaa tgctccgaag
     9841 agtgtgtttg tccttttact tcggtgatca aggaggccac cgaagtaatt tcgaaaaaca
     9901 aaagcacgga taaagcaata atactgataa ctaaataatt tcttttcact atatctcttc
     9961 tttctctttt tctcttctta ttatttactt gtacttactt gaaaattgaa actgctagtc
    10021 gcaactactt ctcgtctaat gatccaaata atcttccgat gccaaaatcg tttttgtcac
    10081 ggacttagga atgacaaatt ctggtgtacc catataacca ggagcaattt cgtattgaga
    10141 aaaagtcaaa actaattgat gctctttgtt caaataaaaa cttcgtgtag gcgtaacaag
    10201 tgttggtttt tctatcgtcc cttcttgaat atcttgctca gtccaatagt acttagatgg
    10261 atcttccttg acttgttcgg ccatctgccg tttgacttct tttgtcaaaa cagatagata
    10321 ggtgtcatct ttgaataaaa gtggaagtga gagctggaca ctgtttttct tgtcgattgt
    10381 gtcgtatctt ttttcaacat ggctatctgc tgctgtttgg gtgatctgcc tttcaatcac
    10441 gagaaaccgg ttatcgtcta cgattttctg ataatctccc aaaacttggt aatgatccgt
    10501 ttcaaaattt ccatattctt tttcagcttt ttcaaaatct gcttgtcctt cgcgaaagta
    10561 tttttgattt aatccatgaa ttgttttatt ttctttctca ttttgtgtat tgatcttcgg
    10621 tacctgaata tcgatttttt cagatcgatc agtaaagcgt tcgcctaaga tcaattcaat
    10681 gactgatcct aagatgggta aatcttctgc aaagcttcga acttgactat taaaaagaag
    10741 gctacttgtt gtaatcatta cgatagccaa agatactccg aacccttgga gacgtctctt
    10801 tctccgcttt gcttttataa atgattgctc ttcgataata aaacgctggc ggatctcctc
    10861 tttaagccct ttgggaattg cttgttcttt ataagttttc tttagttttt ttaaattttc
    10921 tttttgggaa tacatggcac tcttctctcc ttcattctag gatttgacgt aaagcattca
    10981 atgagcggta cattttcgtt ttaactgtgt tttcattcat atccaagata gtcgcaattt
    11041 ctttcaaacg aaatccttca aaaaagtaga ggatcagaat ctctttttcc ggactgtcta
    11101 ttttatctaa aatcatatgg agctctgcaa cggaagtttc taaaggtaac tgttggggga
    11161 tatcttgaat ttcaaataag tccacaggcg tccttttttg tctgcgccaa ctatctaatg
    11221 ccgtgcggat caatatccga taaaaccatg cactaaaatg ctcgatctct ttttcttttt
    11281 caaaatagtt cagggcttta tgaaaactat cttgcatcac atctaaggcc tcttctttat
    11341 catgtacgta attcatcgtg atacggaaca ttttttgata atcagtttcg atgagtccat
    11401 tcagcaggtg acggtatttt tcgatctgcc gttttttctt atatccagta aaaatcattc
    11461 tccactcctt tctgcctcac ttaatatgac gtacaaggtg cgctaaaagt ttcaattttt
    11521 ttatttttta tgtatttact tgggattttt atatacaaaa aagaaggtgt gacaaaaatc
    11581 gtgtcacacc tccttattct gataggctga tcgtctctgt cacaacctct cgtaagaaaa
    11641 taatgtttat tctttttcag agtcagaaaa ttcttcctct tcataatctt catcatcatc
    11701 gtcttcgtct atgatactta aatcttcttc gatatttcct ggcaagtctt cttcatcatc
    11761 tgtcgggtca tctgctccga tttcttgcaa gtcagaatta taagcagcga tttcttcatc
    11821 ttcatcatca tcgtcatcaa acagatcatc gtcatcttct tctgtcagat ctgtatcttc
    11881 tgggtcatcg tcattgtaat cgatcgcgtc ttcatcatca ttgataaagg cgttgacttt
    11941 cttgcgttta cggcgacgtg gagtatcttc atcctcttcg tccattccat ggtttacttc
    12001 ttcatcgatc gaatcgatag cataccatga acgcaagccc caacgattat cccctaatga
    12061 gataaagctg ccgtcaatat tcaagtcagt ataaaattgt gcgagtgaat cacgaatttc
    12121 actgtctgat ttcccaagat agttttggat ctggttagct aaatcagaaa aatccatgac
    12181 atcgccacgt tgttctaaga tcgcgtgtgc tacttcgatc attgataatt cgcttttgtt
    12241 tgcaccttca aatacactaa tttccaatca ggacacgtcc tttcacagtc tactccttat
    12301 catacaaaat cagacacaaa aaatcaaact tttcttttat atttacgctg taaaatccaa
    12361 ggtcaaataa tattcgccga ttttttccgg tcccatgaac agatcataat cgattcgaac
    12421 cttccctcct gtgggacggt ctttcaaact aacatgcagt tctttcgtaa aagtagcaat
    12481 ctggatcata ccgtatggtg ttcgatagga tgtttctaac cgttctttat agccaaattt
    12541 caaacgcatc cgcatttctc ctgcacggat cagctgtaca tgaccatctg gaactaattt
    12601 gatcgttaca ggaatctcat cgcccgtctc ctcctgaatc tctttataac gtatgtacag
    12661 cgtatcgcca attgtcacca tttgcccttt caaatcaaaa taaaaatctt gcacttcccc
    12721 ttgctgtttt acttttgtac gcaatttgat tgaaatcggt gttccttgtg ataattccat
    12781 tattcattct cctttacttc tcatagctac attgttccta gtttcttttg ttttgtcaac
    12841 caacttgtcc atttttacag aaaacctttt ttccaaaaca actctttgat tttagagtat
    12901 aatattgtag aaaatatgaa tttatacaaa ggagccggtt gaatgaaccc tgcgattcga
    12961 ctagatcagc acatttatca aaaaaacgac ttttcccctt ttgcattaac agatatatta
    13021 acggaatatt ctaaagaaca ccagcaaatc tttttacatt tctggcaata tgactgcaca
    13081 gtcatcttag gtatgaagga tgttcgaact ccttttctaa gtgacgggat ccaaacactg
    13141 aaagatgcag gttacgctcc agtgatcaga aattcaggtg gattagggat cgtatcagat
    13201 gaaggaattt tgaatatttc tttgattttc ccccaaagtg acacaaaaaa aataaccata
    13261 gatgacgctt acgagcaaat gctcctattg actaaatacg cttttccaaa ggcaccgata
    13321 caagcattcg aaatcaccca ttcttattgt cctggaactt atgatttaag catccatggc
    13381 aaaaaatttg ccggtatcgc tcagcgtcgg atcaaaaatg ggatttctgt tatgatgtac
    13441 ttaagtgtca acggtaatca ggaaaaacgc gggcaagtca tgaagcgatt ttatcaatct
    13501 gctttaaaag aagactttgg tacaaatggc tatcctgcag tggatcctgc tacaatggca
    13561 acacttgaag aactgcttga ccaacccctt tttgtaaaag aagtcaaaga agcatttgca
    13621 aaagcttttg aaaagctgta ttctgcaagt gatttacagg attctaccga ctggctaaaa
    13681 aaagaaatcc agctggagca atggaacaac caaatccaga gaatggaaca acgtaataac
    13741 ataaaggagc tacattatga caacccctta taaatatcaa atgctgccta tggaaaaagt
    13801 ttttcgtgat ccagtccata actatatcca tgtccagcat caagtaatct tagatttgat
    13861 caattcgaaa gaagtccaac gtctacgacg cattaaacaa ttaggcactt cttctttcac
    13921 ttttcacgga gcagaacata gccgttttac tcattcatta ggcgtttatg agatttcaag
    13981 acgaatctgc gatatctttt ctcgaaattt ttcaaaagaa aaaataggca acggaggctg
    14041 ggatgatcag gaacggctgg tgactttatg tgcggcactg ttgcatgatg tcggtcatgg
    14101 tccttactct catacatttg aacatatctt ccatacgaat catgaagcca tcactgtaga
    14161 gatcatcact tctccagaaa cagaagtgta tcagattctt aaccgagtag aagaaggttt
    14221 tcctgaaaag gtagctagtg tgatccaaaa aacttacccc aacccacaag ttgtccaaat
    14281 gatttctagt cagatcgatg cagatcgaat ggactatttg cttcgggatg cttatttcac
    14341 tggaacagaa tatggaacat ttgatcttac ccgaatatta cgtgtgattc gtccttatga
    14401 aggcgggatc gctttttcca tgagtggcat gcatgcagtg gaagattata tcgttagccg
    14461 atatcaaatg tatgtgcaag tgtacttcca tcctgtttcc cgtggtatgg aagtaatttt
    14521 ggagcatctg cttcatcgcg cacacgagtt gtatcaagaa gatgccagca gttttgaact
    14581 ccattctcaa ttacttctgc catttcttga cggaagcttt actttagaag aatacctcaa
    14641 acttgatgat ggggtcttgg gcacttactt tactcaatgg tctgaatctg ctgatcctat
    14701 tttaaatgat ttagctaaac gttttttgaa tcgtaaacca ctgaaatctg ctactttttc
    14761 tggcaaccgg gattcaaaat tagtccaaga actcactttg ttagtagaaa aggtcggata
    14821 taatcctgtt tattacactg ctgtgaattc tagctacgat ctaccttatg atttttatcg
    14881 cccagaacaa ggcagacatc gcacacaaat cgagattttg cgaaatgacg gaactttgat
    14941 agaattatca caggttagtc agcttgttgc tgcattagcg ggacaagaac aaggagatga
    15001 gcgatttttc tttccaaaag aaatggttga tccgtccttg cgtgatcatt atgatttatt
    15061 tgacgaaact tatcaagaat ttgccagcca tatccgtaat ggcgcattga ttgaaataaa
    15121 ttaaaatata ttggaggaaa ttatgtctat caaactagtc gctatcgaca tcgatggtac
    15181 tttattaaat gagaaaagag aagtaacaaa agaagtaaaa gaagcgattg ccgctgctgt
    15241 tgcaaaaggt gtttcgatcg ttttatgcac tggccgtccc ttaccaggtg tccaggaaca
    15301 gttaaacgag ttgaaccttt ttcaagataa tgattacgtt attacttata acggggcact
    15361 cgtacaacaa acgaaatcag gtaaaatcat cgcccgtcac ggactgacac atgaagattt
    15421 cctagagatc gaagtgatgg cacgccgtgt cggcagtcat ctccattcga tcgatgacaa
    15481 agcgatctac acgcctaatc gagatatcag cgcttatacg atccacgaag caagtttagt
    15541 caagatgccg ctaaaatatc gaacacctga agaaatgaca ccagacatga acatcgtcaa
    15601 aatgatgatg atcgacgaac cagaaatttt agatgcagca attgcgcgtt taccgcaaac
    15661 tttccgtgat aaatacacaa cggtcaaaag tgcgccctat tacttcgaag tactaaataa
    15721 agaagcaagt aaaggtgcgg cagttgcgaa tctcgcacag caccttggta ttgatcaaga
    15781 tgaaatcatg gctatcggag ataacgagaa cgacttatcc atgattgaat atgctggtct
    15841 aggagtagca atgggaaatg ccgtttctct tgtcaaagaa gcagcaaatg tcatcacttc
    15901 atcaaacgac gagcacggtg tagctgaagc aatcaa
//
LOCUS       DBGZHO010000060        15933 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.063, whole genome shotgun sequence.
ACCESSION   DBGZHO010000060 DBGZHO010000000
VERSION     DBGZHO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.063"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            134..3661
                     /locus_tag="ACN3HL_002209"
     CDS             134..3661
                     /locus_tag="ACN3HL_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HHC8007039.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="ACN3HL_002210"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="ACN3HL_002210"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HHC8007040.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="ACN3HL_002211"
     CDS             7449..7790
                     /locus_tag="ACN3HL_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HHC8007041.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="ACN3HL_002212"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="ACN3HL_002212"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HHC8007042.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /gene="pheT"
                     /locus_tag="ACN3HL_002213"
     CDS             9147..11567
                     /gene="pheT"
                     /locus_tag="ACN3HL_002213"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HHC8007043.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="ACN3HL_002214"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="ACN3HL_002214"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HHC8007044.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13001..13738
                     /locus_tag="ACN3HL_002215"
     CDS             13001..13738
                     /locus_tag="ACN3HL_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HHC8007045.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13752..14567
                     /locus_tag="ACN3HL_002216"
     CDS             13752..14567
                     /locus_tag="ACN3HL_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HHC8007046.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14580..15227
                     /locus_tag="ACN3HL_002217"
     CDS             14580..15227
                     /locus_tag="ACN3HL_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHC8007047.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSTLAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15243..15899
                     /locus_tag="ACN3HL_002218"
     CDS             15243..15899
                     /locus_tag="ACN3HL_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HHC8007048.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT         5342 a         2745 c         3376 g         4470 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcactgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaacaa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa ccgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataactaa tagattagaa atggaagaaa tatttatggg agaataaacg
    12901 ttctaagaaa ctttacaaat tactaaacta tcagatataa tgtattttat tatacatctt
    12961 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
    13021 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
    13081 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
    13141 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
    13201 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
    13261 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
    13321 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
    13381 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
    13441 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
    13501 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
    13561 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
    13621 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
    13681 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
    13741 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
    13801 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
    13861 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
    13921 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
    13981 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
    14041 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
    14101 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
    14161 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
    14221 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
    14281 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
    14341 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
    14401 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
    14461 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
    14521 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
    14581 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
    14641 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
    14701 aattatcaaa gaataaagta gtgagcacct tagcaaaggc atatgtagaa ttttttagaa
    14761 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
    14821 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
    14881 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
    14941 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
    15001 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
    15061 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
    15121 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
    15181 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
    15241 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
    15301 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
    15361 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
    15421 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
    15481 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
    15541 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
    15601 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
    15661 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
    15721 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
    15781 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
    15841 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
    15901 agatgattct tttagcggtt gtggcaaact aaa
//
LOCUS       DBGZHO010000061        15929 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.064, whole genome shotgun sequence.
ACCESSION   DBGZHO010000061 DBGZHO010000000
VERSION     DBGZHO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.064"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(10..885)
                     /locus_tag="ACN3HL_002219"
     CDS             complement(10..885)
                     /locus_tag="ACN3HL_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HHC8007049.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1033..1365
                     /locus_tag="ACN3HL_002220"
     CDS             1033..1365
                     /locus_tag="ACN3HL_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HHC8007050.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1477..2685
                     /locus_tag="ACN3HL_002221"
     CDS             1477..2685
                     /locus_tag="ACN3HL_002221"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HHC8007051.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2839..3294
                     /locus_tag="ACN3HL_002222"
     CDS             2839..3294
                     /locus_tag="ACN3HL_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007052.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3656..3931
                     /locus_tag="ACN3HL_002223"
     CDS             3656..3931
                     /locus_tag="ACN3HL_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007053.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3944..6022
                     /locus_tag="ACN3HL_002224"
     CDS             3944..6022
                     /locus_tag="ACN3HL_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHC8007054.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6185..8068
                     /locus_tag="ACN3HL_002225"
     CDS             6185..8068
                     /locus_tag="ACN3HL_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HHC8007055.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            8080..9027
                     /locus_tag="ACN3HL_002226"
     CDS             8080..9027
                     /locus_tag="ACN3HL_002226"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HHC8007056.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9047..9574
                     /locus_tag="ACN3HL_002227"
     CDS             9047..9574
                     /locus_tag="ACN3HL_002227"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HHC8007057.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9637..10290)
                     /locus_tag="ACN3HL_002228"
     CDS             complement(9637..10290)
                     /locus_tag="ACN3HL_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HHC8007058.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10422..11264
                     /locus_tag="ACN3HL_002229"
     CDS             10422..11264
                     /locus_tag="ACN3HL_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHC8007059.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11422..12318
                     /locus_tag="ACN3HL_002230"
     CDS             11422..12318
                     /locus_tag="ACN3HL_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HHC8007060.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12321..13034
                     /locus_tag="ACN3HL_002231"
     CDS             12321..13034
                     /locus_tag="ACN3HL_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HHC8007061.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13054..13572
                     /gene="msrA"
                     /locus_tag="ACN3HL_002232"
     CDS             13054..13572
                     /gene="msrA"
                     /locus_tag="ACN3HL_002232"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HHC8007062.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13569..13796
                     /locus_tag="ACN3HL_002233"
     CDS             13569..13796
                     /locus_tag="ACN3HL_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HHC8007063.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13948..14499
                     /gene="lepB"
                     /locus_tag="ACN3HL_002234"
     CDS             13948..14499
                     /gene="lepB"
                     /locus_tag="ACN3HL_002234"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HHC8007064.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14582..15124)
                     /locus_tag="ACN3HL_002235"
     CDS             complement(14582..15124)
                     /locus_tag="ACN3HL_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HHC8007065.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15361..15759)
                     /locus_tag="ACN3HL_002236"
     CDS             complement(15361..15759)
                     /locus_tag="ACN3HL_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8007066.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         5520 a         2739 c         3210 g         4460 t
ORIGIN      
        1 tcttttttct tatagttttt tcagtaatct tgtctgtggc ttcaaataag taaagccttg
       61 cccttccact tcatgcacat tgatgattga aaggaaagct ttttcgtcaa tctcgtggac
      121 gatcctctta gcttcagtta attcactaga gctaacgacc atatagatga ttttttttga
      181 attaccagag aatgcgcctt ctccagaaag gaaagtcaca cctctttgca gaccggtcat
      241 cagtagtggt gcaatctctt cgcttttgtt ggagacgaca agtagacctt ttgcagaata
      301 tccgccatct aagatcgaat caatcacacg actgaaaaca tacgaaacaa tcaacgtata
      361 catcatacgt ttcaagtcga tataggttaa tgaagcaagt aagacgatga tatcaaatgc
      421 caatagggaa cgccccatag tgatgccgta attttgttct aaaatccgag cgataatatc
      481 actgccgcct gttgttccac ccatgcggta gacgatcccg cttcctacac ctgcaactaa
      541 acccgcaagt agagaaacga tcagtagatc atgctgtaaa ttgatttcta gtggaaccct
      601 ttgccagatc cataaaaaga atgacaaaga aagtgtacct agaacagtat aggccaagga
      661 acgtttaccg aggatctttc ctcctagtaa aatcaatggg atgttgatta ataaagtcgt
      721 ataagctgga tcaataccaa ataaagctct taagatcaag gtgatccctg agactccccc
      781 ttctgctaaa tgattagcga tgttcaagta aacaagacca aatgcataaa tacttgttcc
      841 tataatgata aaaagaactt cttttactgt ttttcgtttg accatatgaa ttccagcttt
      901 caattatgta ttttcacaga atttccattt agaaattcct tcctaaatgt agcatggaaa
      961 ttcgattttc tcaattgctc ttatctagga tttgcgttaa agttttggta agatagtttt
     1021 ggagggaaaa agatggataa aaagcgttct ttatacagta tgcagcagga agtggatgaa
     1081 tatatccagc aattcaaggt ggggtatttc tctccattag ctcagatggc tcgattaact
     1141 gaagaagtag gtgaattggc aagagaagtc aaccacactt atggagaaaa aagcaaaaag
     1201 gcttctgaac cagttaactc ggtagcagaa gaacttggtg atgttttatt cgttacgatg
     1261 atcatggcta attcattgaa tatcgactta actgaagttt ttgaaaaaaa catggaaaaa
     1321 ttcaatcaaa gagaccataa tcgctttgag cgtaaggacg agtaaacaag atgaagtggt
     1381 cctggccttg aagactctga aacggacttg tcaaacagtc accatgcaac tgagtcttta
     1441 tctcaggaca agaaacacgc aggaaaggtt ggaaaaatga aattaaaaca attacctctg
     1501 gaataccaaa aggcaattcc agttctgaaa aaattagaga atgcaggata tgaagcttat
     1561 tttgtaggtg gaagtgttcg tgatatcttg ctgaaccagc caatccatga tgtggatatc
     1621 gcaacaagcg catttccaga agaaatcaaa cagctttttc caaaaacgat agatattggg
     1681 atcgaacatg gaactgtgtt ggtattagaa aatgatgaac aatatgagat caccacattt
     1741 cggacggaat caacttatca ggactaccgt agaccagatc atgtcgaatt cgttcgttcg
     1801 ttggcagaag atttgaaaag aagagatttt acgatcaatg cgtttgcttt gaaagaagat
     1861 ggagaaatca tcgatttgtt cgatggtctg caagatctag aagaacagat cttgcgagct
     1921 gtaggcaatc ctcatgagcg gttccatgaa gatgccttac gaatgatgcg cgggttgcgt
     1981 tttgtcagtc aactagggtt caaattagag gaagaaacct tctacgccat caaagaaaac
     2041 cacgagctat taggtaaaat atctgtagaa cgtataaatg tggaattcat caagatgctc
     2101 ttgggaaatg aacgggccgc gggaatccat gcatttattg aaacagagtg ctacatttgc
     2161 tgtcccggtt tgaaagaaga aggcgaagca cttttacgtt ttgctgaatt accatccgtc
     2221 ccattgaaag aagagagcca agcatgggca ttattgatca gccaactgga tctaaaagaa
     2281 aatgagattc gttccttttt gaaatcgtgg aagtgttcta accaaatgat taaagacgtt
     2341 caagcacttg tccaaggact acgacaacga gaaactggag ctttggaacc attcgaattg
     2401 tacttcttag gcaaaaaaca tgcactgcaa gtagaagaat tgatgatcta ttttgacgaa
     2461 acacctcaga tggatgccgt aggagaatcc tatgatcgtt tacctatcaa gtcattaagc
     2521 gaattagcag tagatggtaa aatcttgcta gaagaaactg gaaaaaaacc tggtaagtgg
     2581 gttagtgaag ctttgcaatt agctgaaaaa gccgtcgtag aacaaagaat aaaaaatgat
     2641 aaaaaacagg ttttggattt tttatcgaaa gaaaaattga tttaaaaaac actagactgt
     2701 atctgctcag ctttgttggc tacttaaagt gggcagatac gtcattagaa gaaaaaacat
     2761 aagatgtgac cacttacata aatttgtgct aaactgaggt agtacaagaa taaattacat
     2821 cataaaggag tctttttaat gagtaaagaa atgacagcgc taaaatttta ttttagaaat
     2881 ggagaaacct ggacgatcaa ccgccgtcat atcggcgatc tttggatcaa acaaatcaca
     2941 acaagttttg gacgaatcaa tggcagtgaa tttgttgaaa tccatccgtg tgctggattt
     3001 aaaatcgaaa tcttccatga aggggacgca gttgcgacac atgatatcaa cctaggcgga
     3061 ctggaaatgg gcatgtttaa tcgcgcattg aaatacgaag atatcgagcg aatggaaatc
     3121 ctttaccgaa atggcacacc tgatcttgtg tacttcccat atctagataa aggaacagaa
     3181 ggattagaca atcaatatca atcaacaaaa atcagcgaaa aaacaggtaa cttgtatatc
     3241 gtgatcaatc cagatcaacg tgtagaagat gtatacgggg aatttttcga ataaatcgat
     3301 ttttacgcaa aaatgaggct gtgaaagaga tgtgtcttat tactactgat aggctgtctc
     3361 ttccacaccg tttattcaga ataagggact gtgacaagat ttttgtcgca gccccatttt
     3421 tttgttgtga taaaagaaca agaaaggcag gaatgggaaa gtaaacatcc ttttgtcaga
     3481 aacttttatc tttcttaagt tttacttgat atctgatact atttggaata gaatgaggcg
     3541 ttgaaaaatt tatggaaatt tctaactagc aataaacgat gaaacaatga aatatttttc
     3601 atccaaaaag aactttgcta taatgatgga agtttgtgta taggagatct ggaaaatgag
     3661 agagagtttt gaacaacaaa aaaaactgtt gcatgatcgc tatggcgccc tttcgatgga
     3721 tgaccgccgt caaatacttt gtaagttgcg taaaagaaat atattgatgt atcgtcagtt
     3781 ggaacgtctg aaacatgatc tgcttcgttt ggagtcaaaa cgtgtacagt gtgaattaga
     3841 ggggaaccaa acacaggttg aagtagtcga aaccaaaatt ttaaagaaaa aagaacaatt
     3901 tttaaaaatg cttacacaaa ataaaaaata aaggggatgg acgatggaat ttgctgagtt
     3961 agttattgta tttgcagtaa cgatcacctt atcgaacata gctagccgca ttttgccaat
     4021 gattccagct ccactgatcc aaattttcct tggagtggta ttaggtctga cagagtgggg
     4081 acaatcaatc gattttgaac ctgaattgtt cttagttatg attattgcac cattgttatt
     4141 tagagaagga gaaaaagcag atatttcttc gattctcaaa aatttcggga caattttgtt
     4201 cttggcattt ggaggagtca ttttgaccct tgtcggggta ggtgcgacgt tatcattcct
     4261 gttgccaagt gtcccacttg ctgcctgctt tgcttttgga gcagcgttag gtccgacaga
     4321 tgcggtagca gtcagttctc tttctggacg agtgaatatc cctaaaaagg cgatgcatat
     4381 tttggaagga gaaggtcttt tgaatgatgc atctggtgtt actgccttcc agtttgctct
     4441 tggtgcgctg atcaccggat ctttttcagc agtaaacgcg gggatgagtc tagtagtttc
     4501 tagtattggg ggagctttga tcggcttttt gcttgtctgg ttcaaacaaa aaataattca
     4561 tttgatcgaa aaagcatcag cacaagatgt cacagggtat ctgctgatcg aacttttgct
     4621 tccttttcta gcctatgtat tggcagaggc atttgatgta tctggaatca ttgctgcagt
     4681 ggcagcaggt attctccaag cttctggttt taggaaaatc tctgtgtttg atgcagaatt
     4741 gtcgagcttg tcccacagta catggacaac tattgctttt acactgaatg cattagtatt
     4801 tatattttta ggaatcgaat tgacgcaagt gttctcgcca gtatggggag acggtttata
     4861 tccaaacggt cttttattag cgattatcgt attaatctct gtcatgcttt ttgtgatcag
     4921 attcatttct atcagtcttt tttatgtatt caaagatggc agtaaaaagt tcaaaaaaca
     4981 gttgaacgag atcttgatct taacatttgg cggtgtaaag ggaacagtca gtttggctac
     5041 gatttttatt ttgccatttt caatcaataa tatgatgttt taccagcggt ctttgctttt
     5101 gtttctgacg gcgggtgtca tcttagtgac tttggtcata gggatcattg tcttgcctat
     5161 gctgacggaa acagaggaag cgaaaagcac ggatttgaat gctttgatga ttttagaaga
     5221 ggtcgttgaa gttttgcgaa aagaaataaa ggaaattgat cgtaatacaa aagaattttt
     5281 agccactgaa gcagtgatag aaaattatca agaacggata cgtgatctgt acttggaaga
     5341 tttaaccgat gatgaaaagc aagaagtaca agaaatacaa gcactgattt tgtcgatcga
     5401 acgggatgga ttggatgaaa gttatcgttc gggcaagctt tcttctaatg gttatcgttt
     5461 ttactcccgt tttctttctc gattcgaaca ttctatcaca agccagattt tgtcttttat
     5521 cggcttttgg ttcattgttg tccgtaggtt aatgcgaatc gttctccatc cgaaaatgtt
     5581 ttggcaaaga agatatgctg atcgtcagac atttattagt gatgaagata tccaagaaat
     5641 cagagagaca tatcaaaaaa atactcagtt gattattgaa agtttagata acttgactga
     5701 tatttatgat gaaacgatgg ttcaattttt tatccagcaa cgcaaacttg aaggaataaa
     5761 aatgaactcg gggaatttga tttcttcgtg gatgatccag caagatagtc tgtttacgaa
     5821 aaaaatgcta agaggttatt atcttgaaag aaaaatcatt gatgaatacg aagttgctga
     5881 aaaaatcacg acgttttctg cgaacagcta tcgcaggaat atcaatttgt tagaatctta
     5941 tacgatgaac aaaccatctg ataacttttc tttccgattt gcgtttcgag caaagtcaaa
     6001 aaaaacgagt ccaataaaat aaaaaggtaa aaattttcaa gttttataaa aaacaaaaca
     6061 tatcagaaca ggatcgaatc ggtcctgttc tttttttgag aacacaaaaa gaacaaatac
     6121 caaaaaaatt ttcctgaagt tcactatttt tatgatacaa tatccaagat aaggagggaa
     6181 catgttgaaa gaattaaaag taactgacct caaaaaaact tatggtgaaa aagatttgtt
     6241 tgaccagatt tcttttttgg tccacgaaaa agaccgtatc gggttgattg ggacgaacgg
     6301 gacgggtaaa acaagtctct taaatattat tgccggtatc gatagcagcg acggtgatcg
     6361 gcaaacagtg ttttatccaa ctgattaccg tattggttat ctttctcaag cagctgaatt
     6421 ttccgatgaa ttaactgttc tccaagcagt ctttcaagga aacagcccct tgatccaaac
     6481 tgttcgagca tatgaggaag cattgatcga actaggggaa aacggagaag accctgatgt
     6541 gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa gaagatgctt ggactacaga
     6601 taccaacgca aagattattt tgcaaaaatt aggaatcagt gaattagata aaaaaatcag
     6661 tactttatca ggtggtcaga aaaaacgagt tagtctggcg caagtgttga ttgatgaacc
     6721 cgatttacta ttactagacg aaccaacaaa ccatttagat tatgaagcga tcgagtggtt
     6781 ggaaaactat ttgaaacaat accgtggcgc actattgatg gttacccacg atcgttattt
     6841 tctagataga gtagcaaacc gaatcttcga actttcattt ggaaaattat acgagtataa
     6901 aggaaattat gaagcttacg tcttagaaaa agcagaacgt gatcgtgtag aagtagaaca
     6961 agaagaaaag cgcaagcggc tttataaaca ggaattagct tggatgaggg ctggcgtaca
     7021 ggcacgtggc accaagcagc aagcacggat caaccgtttc gaagatctaa aggagaactt
     7081 gtaccaagta aaccaagaag atgatttaga gctgaaccta gcgacacaac gtttagggaa
     7141 aaaagtactg gaaatcaaag atggcagtta ccgtataaat gaccaaacac tgctagaaca
     7201 tttagattta ttgattcaat ctcgggaaag actaggtatt actggtaaaa atggtgcggg
     7261 aaaatcgaca ttgcttaata ttctagctgg cagaattccc ctggatagcg gtacaatgtc
     7321 tatcggtgaa acggttcatc ttgcgtatta tacacaagaa aatgaagaaa tggcaccaga
     7381 taaacggatg attgcttact tacaagaagc tgctgaagaa gcaaaaacag cagatggcag
     7441 tcaaatcgga gtagcagaat tacttgaacg atttttattt ccaagattta tgcatgggac
     7501 actgataggc aaactttcag gcggagaaaa acgccggtta tttttgttga aactgctgat
     7561 tcagcaacct aatgttttat tattggatga accgaccaat gatttggaca tagcaacatt
     7621 gacgattttg gaagattatt ttagaagttt tccaggtgct gtgatcactg tttcccatga
     7681 ccgttatttc ttggacaagg tagcagataa gttattagta ttccaaggaa acggaaaaca
     7741 agaactttat tacggaaaca tgtccagtta tttactgaag caaaaagaga cccagcagcc
     7801 tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct gctgaaaaga agaaattatc
     7861 ttacatggaa caaaaagaat gggaaacgat tgaagatgag attgcagaac ttgaagaaaa
     7921 aatctcattg ctccaagaag agatgaatca tcaaggagat aatttcactc gattacaaga
     7981 attgcaaaac gacgtatctg aaacagaagc acaacttgaa gaaaaaatgg cacggtggga
     8041 atacttgagt gaatgggtag aagattagga ggaaaaagga tggaacaagc gtatcttgac
     8101 ttaggaagaa aattgttgga agaagggcat cgtaaagaag acagaacagg cacaggcaca
     8161 ttaagcttat tcggatacca aatgcggttt gatctgcaaa aagggtttcc tttgttaaca
     8221 acgaaacgag taccttttgg attgatcaaa agcgaattgc tttggttttt aaaaggagat
     8281 acgaatatcc gctatctatt acaaaataaa aaccatattt gggatgaatg ggcatttgaa
     8341 cgctacatca aaagtccaga ctataatgga ccagatatga ctgattttgg ccatagatgt
     8401 ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga gcaagctttt ttgcgagaag
     8461 atcctaaccg atgattcctt tgctgaaaca tacggcgatc ttggacacat ctacggctat
     8521 caatggcgtc actgggaaac aaaagacggt ggctttatcg atcaaatcaa acaagtgatc
     8581 gaagcaatca aaaagactcc tgattctaga agattgatcg tttctgcatg gaatccggaa
     8641 gatgttccta gcatggcttt gcctccttgt catacgatgt ttcaatttta tgttcaagag
     8701 ggacggctaa gctgccaatt gtatcaacgc agtggggatg tgtttctagg cgttccgttc
     8761 aacattgcaa gttatgcgtt gctgactcac ctaattgcac atgaaacagg tttagcggtt
     8821 ggcgaatttg ttcacacatt aggagatgct catctttata tcaatcatat cgaacaaatg
     8881 aaagaacaat tgagccgaga aatacgcgca tttccgactt tagttttgaa tcaggaaaag
     8941 cagtcagtat ttgattttga gatggaagat atccaattag aaggatatga cccacatccg
     9001 gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat gagaaaatgt tagctgcaat
     9061 ttgggcacag gatgaaaacg gattgattgg aaaagaagac cgtcttcctt ggcgtttgcc
     9121 aaatgatctg aaattcttca aacaaatgac agaagcaaat acactagtga tgggacgaaa
     9181 aacattcgaa gggatgggta gccgtccgtt gccgaatcgt cagacgattg ttttgacgag
     9241 agattcttcc tataaagcag aaggcgtgca tgtcatgcat agtgtggaag acgtgcttgc
     9301 tctggaaaaa gaaacagacg gtatcttttt catcgctgga gggtcagctg tttatcaaga
     9361 atttctgcca ttttgtacga tattataccg tacagtcatc catcatgtat tcgatggaga
     9421 tgcttatttt ccacctgttg actggtctga ttggtcactg atcaatacta gtcaaggaga
     9481 aatggatgaa aaaaatcgtt atccgcatca atttgaaacg tatcagcgta atgagaatcc
     9541 tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc tatggataga ctagctgtta
     9601 tttagagctg tcccatccat agctttattt tttttattaa gtaaagaata aaacagagaa
     9661 gtacataaaa cctgcaccta acataacaaa caaatgccaa acaacatgca tatagcggat
     9721 agaattcaag ctataaaaga atgcgcctat cgtgtaagaa agcccgcctg ctaccatcaa
     9781 aataacacca gtcattccaa gagagtgata aagaggaaca gcagccacga cacagagcca
     9841 ccccataaaa atatagatga tcgtagatac ttttgatact ctctcccgtt tatgcaacgt
     9901 caacgcttta tatataatgc caagaatcgc aaacaaccag attaatacaa ataaagtcca
     9961 acctagccat cctcggatac tcagcaaaca aaaaggagta taacttcctg caatcaaaag
    10021 aaaaatcgaa ctatgatcga atacttggaa cacctttttt gcttttgtaa aaatcaatga
    10081 atgaaacaaa gtagacgtta aaaataaaag aatcatcatc gatccataga tagcataaga
    10141 gacaatatgg agggaggaat gcaagtgggc accttttact aaaagaacca ctagtcccgc
    10201 gatactcaat ccagtcccaa ttccatgggt gactgcatta aacacttcat ttaatatttc
    10261 atacgttcga ttaaatttcg ttttttccat gaaaacggct cctttactag gtgtaattaa
    10321 tgaaaaatca ttatttgtct gttatactaa aaatagaaat tgtcttacat gtagtttaac
    10381 atgaataagg catcttgtta aagaaagaga gagagaaaat aatgacaaat gtaaaaatcg
    10441 taacagattc ttcatgtacg atggaaaaaa atgtacgcga tgctttaggc attcgtgtca
    10501 tgccgctatc catcatgatc gacggaacag tatatcccga tgatgaccaa ctagacggcg
    10561 aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc caaaacaagc caaccaccaa
    10621 ttggagaatt catctcgatg tatgatgagc taggagaaga cggcagtgaa gtgatttcga
    10681 tccatatgac aaaaggcttg agtggaacag tagaagcagc aagacaagcc agtaatctaa
    10741 caaaaacgaa agtaacggtt atcgacagtg ataccactga ccaaggatta tcttttcagg
    10801 taattcgagc agctgaatta gcaaaagaag gtaaaacagt agagaaaatc cttgaagaag
    10861 tcaaaaaagt acaagacaat acaaaattat acatcggaat atccacacta gataacttgg
    10921 taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc tagtgttttg aacatacgcg
    10981 tggtgatgaa tttcgcccat tctgaattaa tccctgtaac taaggggcga ggaaagaaaa
    11041 cgttcgataa atggtttaat aatttgaaaa atgaactgaa agaattgcca aatgtgcgac
    11101 aaatcggtat ttcacatgcg gatgcaaaag aattggcgca agaattcaaa gagggtttgc
    11161 aagaattatt cccggacatg catatccctg tactgcatac gaatccggtt atcgctacgc
    11221 atactggtaa agacgcgttt gcaatcatgt attatgtaga ttagtcgaaa agaggataag
    11281 ccctcagcct gaaaggcttg cagcttattc tctttttctt tataaaatta ggaaaataat
    11341 tgttttcttt tttcataaag actacctttt tgataaaatt tttgataaca ttagaaccaa
    11401 tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac atttgatcct cgttttgttc
    11461 ccattattaa ttgcgatcat catctatgca ggtttagctg cttctatacc gaaagctggc
    11521 ccactaatga aaccagtaac tactgtgaga gaagatccaa ataaaaaaga aaaacttcac
    11581 tacatagcta tcggagattc gctgactgaa ggagtaggag atcaaaccaa gcaaggagga
    11641 ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata atttgaccgc ggttgaaaca
    11701 gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct taaagcgagt aaaaacaaaa
    11761 gaagaaattc gaaacaatat caaaacagct gattttatca cactgactgt tggcggtaat
    11821 gatttgatga aagttatcca aaataattta ttcgggttaa cggtcaattc ctttaaaaag
    11881 ccactgaaaa actatcagga aaatgtcaca gaactattgg aagaatttcg atccctcaat
    11941 aaaaccgcac ctatttacat tttaggcatc tacaatccat tttatttgaa ctttcctgag
    12001 atcactgaca tgcagacaat tgttaacaat tggaacaaag gaacagaaac ggtgacaaaa
    12061 aaaatgccga actgctactt tatcccaatc aatgatttgc tttatcaagg attgaatcag
    12121 gaagtaggtg tcacagaaga aggaacagat caaacaacta gcacgacaga aaatctaaat
    12181 ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc atccaaataa tttaggttat
    12241 caattgatgg caaatgcagt gagagatcag ctgatcgaga cacaaaacca atggttagag
    12301 aaggaggatg atcaataaac atgaaaacaa gatctgacgt atcttcaaac aaaacaaaga
    12361 aaacaaatta ctggaaattc gccttcctta tccttcttgg ggtagtactt ggttcgaccg
    12421 tatttttagg cagccgtatt tttgctaatc gggaaccaga actcccagaa ataccagctc
    12481 ttacggaaag acaaggagat cctgtcttaa cgatcaattc aaataaagaa aaagtcaatc
    12541 aaatcatcag ctttttcctt agtgagtatc aaaaagatag tgatattgaa tataaatttt
    12601 atttggaaaa tgaagcacta ctcaatggta ctttcgaagt actaggtttt cctatcgatt
    12661 tctatttata ttttgatccg tatgtgatgg aaaacggaaa tgtccaacta aaagctagaa
    12721 gtctttctat cggaacattg agtttgccaa tcaaagatgt gatgaatatg atcaagagaa
    12781 actataaatt accagattgg atcgaagtca atacagatga tctgactatc atgcttaggt
    12841 tggatcaatt ccgaatgcaa aacgggatgt atattaaagc agataaaatc gacttagtaa
    12901 atgatgacat tcggtttagt ctatatttgc caaaagatac ctctgatgct tcaaacaact
    12961 caaataccaa caaaactagc accagcagta ctgaaagcaa gacaaaagaa aataaaaaat
    13021 catcggatga gtagtattag agggggaatc ataatggaac gagcaatatt tgcaggaggc
    13081 tgcttctggt gtatgatcca gcctttcgac acgcttcctg gtatccatac agtgatgtca
    13141 ggatatactg gagggcatgt accagatccg acttatgaac aagtaaaaag ccaaacgact
    13201 ggacatacag aagcagtgga gattatctat gatccaacat tgatttcata tgaacaatta
    13261 gtagaacttt actggcagca aactgatcca actgacgctt tcggacaatt cgaggatcgc
    13321 ggtgacaatt atcgcccggt gatcttttat ttgacagaag aacagcggat cattgctgaa
    13381 aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac agccaatcgt tacaaaaatc
    13441 gaaccagccc aaccatttta tctagcagaa gaagaccatc aagagtatta taaaaagcat
    13501 cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct ttatcgaaga aaattggagg
    13561 aacgaagggt gaatcgaagc ttttttcatt atttaatgac actgcgaggc ggtggcacac
    13621 atgatgcttt atctgttttc gctacagaag ccggtaaaga catccaattt cctaagcaca
    13681 gctctagcta cgaagaaatt tctaattatc tggaactgaa tgtcgactat ttgccgtcca
    13741 tggatatctt tgacgaagca tgggaaaaat atttagaaaa taatcatgac atataagaga
    13801 tagttttgta ctttatgatc aaaaaagttt tttgtccaat agcctaattg aaagaattat
    13861 ttttatttca gctatctagt cgcatttttt tgatattttt cttataataa agaaagaatg
    13921 aaaaaaagag ggatggattg atagagattg acaaaaaaac aacgctatat taatcgcttc
    13981 tggcttgtat tcaaatactt acttgtttct gtattccttg cgttcatgtt gcggggattt
    14041 ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa acgtgttgaa gcaaggtgat
    14101 atggttgtga tggaaaaatt ttcggagatc agacgatttg atattgttgt ttttcaatta
    14161 gcagatggca cgatttatat caaacgagta atcggtcttc caggagaaaa tgtcagctac
    14221 caaaatgatc aattgaagat caatgggaaa gtagttaagg aaccttatct aactaaaaac
    14281 ctgaaatcag atcatgcaaa tgcatcctat acgacggact ttacactaca agagctaacg
    14341 ggacaatcca agcttccgga agataattat tttgtacttg gagataatcg aagagtttca
    14401 aaagatagtc gttcgtttgg cacgatcaat aaaactgata ttctaggtaa agcaagattt
    14461 gtctattatc cacttgatga aataaaatgg atccagtgag aaacaataaa gcgtgcagtc
    14521 tgttgagact gcacgcttta ttgtttaatc caaaatcagt ttactacctt agtacgtaaa
    14581 atcaaacagc tcgtttaaac acttttctag cctctaaagt tttgataaat gaataaacaa
    14641 ccattatttg aatagggatt tggatcatat tcctgatgaa tctacctaga aaaattactt
    14701 tgaaatctgc accaaacaaa acagacatca gccaagaatt gataaaaagg ctgactggga
    14761 tcataatcaa taattgggca gcgatgacgg aaggcaggtt tatcttttta tgatataaaa
    14821 ataagccatt aataaatcca ccaaggaaag ccgtgataag aaaagcagct tgaaacgttc
    14881 ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat ttcaagcaaa ccagcccaga
    14941 tcggtccata tagataaccc ataagcgcca tacttaaaaa tccgaatgtg atttgaaaat
    15001 aagcaggacc aatcgctatc ttgtataaga tgacatcaag ggctaataaa agagcagagg
    15061 tcgacaacaa tcttgcattc atttcgggca atctaaaaac gtcttttgca atcaaagtgt
    15121 tcaaaatatt ctctcctttg tcagttaata ataaaaggat accataaaat caccaatgtg
    15181 tcatgacaca ttggtgattt acatacactg gcatctaaca attaaaaaaa gggtgagaag
    15241 actgctttta taaactgtaa aaaagagatt gtacgaataa aaaaaataga ggcggagaat
    15301 acttatcgta tcatccgcct ttgttttttt gttataaaaa acgtcagatt agttatctgc
    15361 ttacatcttc atccatacgg gttctaatgt atttccgtct agatcttgga cttctaatga
    15421 aaacatttct tcttcaggca ttcccatatc tacttcgtgg aaagtaccac cattttcttt
    15481 tgcaatttga gcaaattttt ttacttcatc cgcattttca acactaaacg aaatcaaagc
    15541 accacttgtt tttttattat cagctatttc tttatctttt ataaattttt tataaaaatc
    15601 atgagagaga agcattatcc aaaaagtgtc atcccatacc attgaaccag cttcttcagt
    15661 agaaaattct tcattttttt taaaacccag cttttcataa aaagcaacgg aacgattgac
    15721 atcagcaaca ggaaaattaa caaaaaccat actattcatt tgtttcgtct cctttctgtt
    15781 ttgttcgtct atcatctctt atttaggaaa cgctgtcaaa aatttagatt catatataga
    15841 aaccaaaata aaaatttgca tcatcaaaaa agtgaagatg tgatagaatg aggactggtt
    15901 cactttcact taactaatag atggaattt
//
LOCUS       DBGZHO010000062        15707 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.065, whole genome shotgun sequence.
ACCESSION   DBGZHO010000062 DBGZHO010000000
VERSION     DBGZHO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.065"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1065)
                     /locus_tag="ACN3HL_002237"
     CDS             complement(<1..1065)
                     /locus_tag="ACN3HL_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007067.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKI"
     gene            complement(1076..1744)
                     /locus_tag="ACN3HL_002238"
     CDS             complement(1076..1744)
                     /locus_tag="ACN3HL_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HHC8007068.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1875..2459)
                     /locus_tag="ACN3HL_002239"
     CDS             complement(1875..2459)
                     /locus_tag="ACN3HL_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HHC8007069.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2790..3023)
                     /locus_tag="ACN3HL_002240"
     CDS             complement(2790..3023)
                     /locus_tag="ACN3HL_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HHC8007070.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(3038..3988)
                     /locus_tag="ACN3HL_002241"
     CDS             complement(3038..3988)
                     /locus_tag="ACN3HL_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HHC8007071.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(3985..4827)
                     /locus_tag="ACN3HL_002242"
     CDS             complement(3985..4827)
                     /locus_tag="ACN3HL_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HHC8007072.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            5149..6336
                     /locus_tag="ACN3HL_002243"
     CDS             5149..6336
                     /locus_tag="ACN3HL_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HHC8007073.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(6428..7168)
                     /locus_tag="ACN3HL_002244"
     CDS             complement(6428..7168)
                     /locus_tag="ACN3HL_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HHC8007074.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            8086..9312
                     /locus_tag="ACN3HL_002245"
     CDS             8086..9312
                     /locus_tag="ACN3HL_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8007075.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(9472..10089)
                     /locus_tag="ACN3HL_002246"
     CDS             complement(9472..10089)
                     /locus_tag="ACN3HL_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007076.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(10772..11767)
                     /locus_tag="ACN3HL_002247"
     CDS             complement(10772..11767)
                     /locus_tag="ACN3HL_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8007077.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(11862..12734)
                     /locus_tag="ACN3HL_002248"
     CDS             complement(11862..12734)
                     /locus_tag="ACN3HL_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHC8007078.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(12747..14174)
                     /locus_tag="ACN3HL_002249"
     CDS             complement(12747..14174)
                     /locus_tag="ACN3HL_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HHC8007079.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(14228..15502)
                     /locus_tag="ACN3HL_002250"
     CDS             complement(14228..15502)
                     /locus_tag="ACN3HL_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8007080.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLFVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         5212 a         2873 c         2238 g         5384 t
ORIGIN      
        1 aattttttct tgctgatctt tactaactat ttcattcccc agggctaact cgctcctcac
       61 tgattctgtg aaaaattggt aatccatttc ttgcattact aaaaacggcg atgacaaatt
      121 ttttttattt tcgattatct ttcctttggt agggcgaata atcttcatga gtattcttag
      181 taaggttgtt ttccccacac cgtttttccc taccaaacca ataacatctc caactttgac
      241 atcaaaattt atgtctttta gaatattttc ataagtaatt tcttcaactt ttaatacatc
      301 tgcacttacc ttttcgatat agggaacttc aatcgaacta ttaaaaatgt caaatttcct
      361 taatgcgtta ttgttttcag tttttaacaa ctgaatagtt gtagttttta cagttctatt
      421 tttaacaaat agaacttgat caattaattc tttcaaatag taaaaacgat gttcagctat
      481 aacaatagta aatcctttat tttttaaatc acaaagtaag tcagcaagtt tcttagtcgc
      541 tttgaagtcc aaatttgaag acggttcatc caatataatt aatttagagt ttagcgataa
      601 actacatcca atagaaattt tctgccgttc accacttgat agcgaaaaaa tgtttttatc
      661 taatatattt gaaagatcta ataattcagc taattcattg attcttttat ccatatgctc
      721 ttttgtaaat ccaaagtttt ccatcgaaaa tactaactca ctcgttgtat ttgttgtaaa
      781 gaattgtcct ctaggatttt gacttacgta gccaatattt tttgatatac tttcttgtgt
      841 taaggattgt agcgagttat tttcaaataa aatttcccca accaattttc cgtcataaag
      901 tcttggaata agtccattca ttaactttaa tagtgtggat ttcccactcc cagaagaacc
      961 agtaatcaat gtaagactgc ctttttttat tgaaaaatta aggtcaacaa gcgcttgttc
     1021 cttaacatcc ttatatgaaa aagaaacatt gttaaattca aacaattctt tcacctcaaa
     1081 tcaaaatact taagaaaaaa atagtaacgg aaaacaggat gatatagtct aataagctca
     1141 tgtttgtttt atagtaagaa cttcttttca caggagattc tatccccttt gttattgcat
     1201 tagcggtcat ttcttcagca atcatagttg cacgtataag aacgggaact aacagaaatt
     1261 ccaaatattg cagaggctga aaaaaagaca agcgaatgtt tctcattttt aaagattctt
     1321 taatcattct tatttcagaa cgataagtcg gaaagaatct gatcactact gtaatactta
     1381 acattatttt tttcggtaaa tgtatttttt ctaaagagga taataattca ttgctagtat
     1441 agacactaac caacaaccat gagatcatta cgaccggcaa cattcgaaat acaatatata
     1501 aggatgtccc aaaaaatata gtaaaaaact ctatcttgat agcatcaata attttcatta
     1561 ctaaaaacag aactgaataa atcaagatga aataaataca tgtctttatt ttacgaaaca
     1621 tcaatactaa aactgtagca ataatgaaac accccacttg aaatatattt ccctttccta
     1681 aaaaaataat gaccggaaaa aaaatattta aagtaatcaa ggttaacgga ttgatttttg
     1741 acactctttc acctccaaaa aataagatcg cactgttatc ttaagctgac aaaaatgcac
     1801 cgttattcag ataacagtgc gatcttatca aaaagcataa ctgagaacaa ttctcaatgc
     1861 aagctttttt ttaattaact cagtaattca atccacccag gaacagaaaa ttgatacaat
     1921 cttctggtta atagcatagt cttttctttt gaatagctat gcttcaatat atcatagaat
     1981 gtagcgtaga atgagtaaat gtagaagtgg atttcttctt cattaaagac taaattttga
     2041 ttgatcattc cgatagtctt taacttatct agacaacaga ctgtcttttt tgtcacaaat
     2101 gatgtaattt tttcaacaat atcttgatat ttggttccag ctgattggaa taaaaccaaa
     2161 tcgaatatac gtttattctc aaaaatataa ttaataaatg gatctaattc attgaagttc
     2221 tctctccaac ttttctctat atctatattt tctaagttta agaggtattt ggtaaactct
     2281 tcattataca tattaataag cgcattaata tgcggctgaa taatttcttc aaataacgct
     2341 tccttagaag taaaatgttt ataaaaagca cccgtagtta cgcctgcggt caagcacagt
     2401 tgccttatct tagtttgctg aaatccttct ttttcaaaat ggcttagtcc actttctatt
     2461 aatttttggt gagttgtaat ataatctctg gtttctatgg gtacttcctc ctaataagat
     2521 gaattaacta tattatctta cacaggactt gaagtttcaa tcgttaacgt ctattactga
     2581 actcattcct tagagctaaa ctaatgagaa agagcaaaat aactgataca aaaagcaatc
     2641 ctacaagaat taatagactc atctaaatca ttcacctttt ctaaaataat ccgagaaaga
     2701 tttaaaaaaa ttatatccag ctattagggt aagtcctatc ataatcactc caatagccat
     2761 tttcttatcc tccctaaaaa taaagtcttt tacttaaaac cttttttgta atcgtcaata
     2821 aattttttcc ctttatcagt taattgaaat cctatatcta aatagtcctc atatctaagt
     2881 ttagccagca tctcacttac agatgctgga ctaacactta gaacttttgc taaatcatta
     2941 ttttttaatt tcttttttct ttttgataat tcctgaattg ctagtaaata aattagtata
     3001 gtagtcgttt taatttgtac catacctacc ctccaaatta tttcgaaagg ccttcagcaa
     3061 ttttatccag gttccatttc atcatcgcat agtaactatc accatcttgt cctttttctg
     3121 caattgaatc agtaaaaatc gttgaataga taggaatatt ggtatctttt gatactgttt
     3181 tcattggtct atcgtccaca ctgctttcta cgaataagga gggaactttt gttgtgcgta
     3241 atttttcaac taagtgtttt atttgatctg gtgttccttc ttcttcagtg ttgatttccc
     3301 aaatgtaagc agaaggcaca ttatacgctt tcgagaaata tttaaagcat ccttcacttg
     3361 taacaatcat ttttttatca ttcggaattg aagcaaattt agatttagct tctttgtcta
     3421 gagaatccaa tttttcaata tacttatcta gattttcttt atagaatttt ttattatcag
     3481 gatctttttc cgctaactgt ttttcaatat ttttagcgta aataataccg ttttctaaat
     3541 ttaaccaagc atggggatct tccttccctt tctcactctg accctctaag taaataacat
     3601 ctatgccatc acttgctgca aaatagtctt tgttttcctc tttgttcgca ttttttacta
     3661 attttgtaaa ccaagcattt cctccagttt ccaagttaac accgttataa aaaatcaaat
     3721 ctgcttttga agttttttga acatcttcag gcaaaggttc atattcgtgg ggatctttcc
     3781 caataggtac gatactgtgt aaatcaattt tatcttttgc tatattttca gtaatatctg
     3841 ctaaaatcga attagtaact actaccttta atttttcgtt cgaagccact gtatctttgt
     3901 ctttactatt tgttgaacat gccccgaata taaaaagagc aatcaaaatc cccagacttc
     3961 ccagtactgc tttccatttt ctcatcataa ctttctctcc ttctttctta aaaatttttg
     4021 ttttggtgag attagaaaac taattacaaa taagaatgcc gctgttaaaa caatacttga
     4081 tcctgctgct atgttaaaac tataaccaat gaacaaacct agcaatgatg agcacgctcc
     4141 gactgtcgcc gaaataaata tcatagtttt taagctgttt gcatataaat atgctgtagc
     4201 agctggtgta attaacattg caacaattaa tatagttccc acactttgca tagctgttac
     4261 tgctactaaa gttaatagaa tcattaatag ataatgataa aaactgacat tcatccccat
     4321 tgcttttgcc attaatggat caaaagaagt gattaataat tctttaaaaa atagaacaac
     4381 tgtaaccaac actaaaacag aaacgccaat tgtaatccac ttatcaatat cttgtacagc
     4441 taaaatattt ccaaataaga tatgaaataa atccgttgag ctatttgcaa ctcctataag
     4501 gataactcct aatgctaaaa aagaactgaa agtaatacca attgctgtat ctccttttat
     4561 tacactattg ctttttataa aagtaataat gatagaagct aatagaccaa atacaatcgc
     4621 accaataaaa aaattaatac ctaaaatata agaaattgct actcctggca aaacagcatg
     4681 agaaatagca tcacccataa gagacattcc tcttaaaata ataaaacaac ctactgttcc
     4741 agaaacaatc cctataacta cagatgtaat tagagcattc tgtaaaaagt gaaagtcata
     4801 cagaccatta ataaaatttt gaagcatatt attccccctt gtatattaga gttagggttt
     4861 taaccttccg gttttgattg gataacccta tgaaccatcg ttattttaat ttggtattaa
     4921 ctcatttctt ttgagataat atatttattg gattgagagg ctaagccgtt ccccccttgg
     4981 gccattgaac ccgcactcga gagactggct cctctctctg ataagtggat tgcgtatgag
     5041 ttagatgttg aaagtcctta ctttactccg tatctcgtac aaggtagtga cgcttttcag
     5101 ttgagtggat ttcaatccaa aattcttttt ttgaaaggtc agatatacat gtacttttta
     5161 ggcattgata tcggtaaacg cactcacgtt gcttctatca tgaacgagga aggaaaggta
     5221 ttactaaaag gtttttcatt tcctaacacc actgaaggag cagagtcatt aattgagcga
     5281 atggtcgact attccggagc acccagtgac tttgttatag ggatggaagc cacggggcac
     5341 tattggctgt ccatcttttc ataccttcac gaatcagatt atttgattca cgttgtgaat
     5401 ccccttcaaa cagacggatg gcgtaaaggt acagaaatac ggaaacgaaa aaacgatatt
     5461 attgattctg ttttgattgc tgacttaatg cgctatggct catttgtcga aacggtctta
     5521 tccgatgaaa atgttttttc tttgaaacaa ctttctcgtt accgaactta tttagtaggt
     5581 acagcgagcg acttcaaaag aaaaattata gccgtattgg atcaagtctt tccagaatac
     5641 gcgacgattt ttaccaagca gggcgttttc ggaaaagctt ctaaagagtt attgctggcg
     5701 tttagtgccc cgatcgactt agaaaacatt tcctcagaaa ctttggccca atacttagct
     5761 gagttaagca ggaaccgaat caaggcagaa aaagcggacc aattgaagca agcagcttct
     5821 aactcctttg gagtaaaatt tgctcaagaa gcgttcacct tccaactacg ttcaatgatt
     5881 gaacaattaa aattcattga aagccaaata aaggaaacgg aaagagaaat caagcacata
     5941 atggacactt taaattctgt tattctcaca attcctggaa ttggtcctat aaacggtgcg
     6001 actattcttg gtgagatcgg agatattcaa aaattttcta acccgaaaaa actcgttgct
     6061 tacgctggga tagacgcttc cgtgacacaa tcagggcaat atgaggcaac gcataatgtt
     6121 atgagtaaac gagggtctcc atatttgcga aaagccttgt tttcggcggc tttagtagct
     6181 tctcaatgtg atcctgtttt tagtgcgttt taccagaaaa aagtttccga aggaaaacat
     6241 catctaactg ccttaggtgc ggtttctcgt aagctttgtt acgtgattca tgctattttg
     6301 actaaaaacg agccttatat aattgtttct gattagctat tgaacattca aaaaaactaa
     6361 tggtaagaag cttatttgtt gtaccctttt ttcggaatta tctgttataa aatatttttt
     6421 gatttggcta atttttactt gactctatat agttagtctc tccaataaat atagtatctc
     6481 cataggcttt ttttaaattc tcttcattaa atacagattc tacacttccg tgagcaatta
     6541 gatttcgatt caaaagaata atattatcaa aatacttctt taccttgctt aaatcatgat
     6601 gcacaattag cactgttttt ccctgatgtt tcaattcttt taacgtatcc ataattattc
     6661 gttcactaac taagtctatc cctacaaatg gttcatctaa aaatatgaaa tccgcatttt
     6721 gagcaagaca tcttgctaaa agtacacgtt gaaattgtcc tccagataat tctcctattt
     6781 gatgattaga atattttccc atatcgacct tttccaaagc ctttgaaact ctttgccatt
     6841 ctgcattttt aattctttga aaaactttca ttccggcata tgttcccata gatacacatt
     6901 cttttacttt tattggaaaa gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct
     6961 tcaccagttt tttattgata tcttcattat taatggagac ctctccctga tgagggataa
     7021 tatttaacat tgctttaagc aatgtagatt ttccagcacc atttggacca ataatacctg
     7081 ttaaagcacc ttcttgtatt tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac
     7141 aaacattaag ctttttcact tctaacataa ctttctcctt ctaaatgata atgattatca
     7201 cgatcatatg gtatacaaaa attatatttt agtcaaccct aaattttata atttagattt
     7261 ttttctgttg ctgaagatta gaatgacaaa actatttgaa actacgcgta tagtaagtag
     7321 ctttcaaaat atataaaaaa ggagcgttct caaatgagaa catgctccta aaactacttt
     7381 attggcgtat ggaaaaatta tacttaaagt ggatagcggg ttgaataagt tgataagcat
     7441 caaaacattt ataaaaatta ttcaagacta tgtctgttcc atatacaaat atgaaaatca
     7501 gtaaactcca tttaactttt ttcgtagtgt gtctttttat acatgtttat cgttattaat
     7561 agtgaatagg aaaaaaccta tttttgatca ttgacaatta aatacaattt ttgaataacg
     7621 atccctgcta ttcgagctag aaactcaagt acgccatgac ctgattagcg acaaatactt
     7681 agagatttct ttttgttctg ggaaaacaaa atgccatgac aatagcagca aataatgata
     7741 cttccgtaag gctcgccgta aactggggag aggtgaaatt cctatgtgct tacccaaagc
     7801 aattcaaaaa ttctaatctt ttttaggaga tgattttata aaattgagag tctacttgaa
     7861 taaaaaacaa acctgtgagt ttctaggaat tgataataat actttagata agtggattcg
     7921 tatatataat tttccagtaa tcagaattga cggtatagtt cgctttgaca tagaggatat
     7981 caaagatttt atgaatacat ttaaaacaat ttgaaaattt cttctcgccg catatactaa
     8041 gaatagcgaa atatactgcc ttacttttta agggagtgag gaattttgcc tacaaaactt
     8101 tcaaatggga aatataaaac taatctgagg tatccaaaaa aattcagaga aatcactgga
     8161 attacatcag aaaagtatca aaaagtattt ccaactaggc aattggctat taaagccgaa
     8221 aatgcaatga aaaggaaaat tgaaacagtt ttaagagagg agaatgcaaa ttcactagaa
     8281 ttaaaaggaa aaataaaatt taaggaattc tatgaatcaa aatggcttcc tagatatgaa
     8341 ctaggtcaga ctactagatc aaaaagagct ccaagttacg taacaattag taatactaaa
     8401 gatatattcc gattgcacat ccttccaatg tttggtgagt atgcaatgaa ctatctaaat
     8461 tcaaatactg agataatatc agatgaatta acaaaaaaat cgaaagaata cgcaaatata
     8521 aaaattatca aaggatatgt ccgttctatg tttgatattg cagaaatact aaattatatt
     8581 gaatttaacc gaactaccaa aattattcaa tgtatcactg cacctaaaaa aattgcttta
     8641 gaagaaagaa ggatacggga aggtaatcaa gcattatcgt cagaagagct tattgcttgg
     8701 atagaagcag taaacactga cttgaataat cacttgctta ctcttcatga ctatactctt
     8761 ttcatgctta ccctatatct tggtgataga aaaagtgaga cgtatgcttt gcaatggaaa
     8821 tatatcgact ttgagaaaca aacggttcgc cttaaacatg ctttggataa atatcaaaaa
     8881 aagaaattta caaaaggtcg aaaggatacc gtaattcaag tacccgaaat tgtaatggca
     8941 ttactaagca aatggaaatc agtgcaagct gagcaattgt tgagattaaa aattaatcaa
     9001 acaccagatc agtatctctt tacctatact aaaccatccg gagaagtaaa ttgccctgtt
     9061 cacgctgatt acctaaacta tcgaatcaat tcaattaaaa gacgacatcc tgaattggct
     9121 catttatctc cacataagct tcgtcatacc tatgcaacta tagctagaca aggcggagca
     9181 aatatgaatc aaatatctag tgctttaaca cactcagata tttctacaac gagaatatac
     9241 gtaaatacac cagatgtagt agataaaact gtttttgaag cctttcagag aggattgaat
     9301 aaatgtgatt agtatgtgtt cttaaatgtg ttcttaaaca agaaaaagac acttttcaaa
     9361 caattgaaaa gtgccttgaa acattgatat ataaataata ttaacgttta gagaattgag
     9421 atgctttacg agcctttttg agacctggtt tcttgcaaaa ttatattagc ctcaactgaa
     9481 agatttattt ttttgctccc taacttcatt agtaatacca tgtttcattc gatatcttct
     9541 aaacgttcta cgattaatcc ctgttagctc ttcaacttct ttatctgtag atccagtcaa
     9601 aaacaaatta aatgctaatt gaagtcgcgg atcattctca cgatatttta gcgtacctcc
     9661 cttgtatttc ccttttgctt tagcgagtgc aattccttgt tgttgcgttt cgcgaatata
     9721 ccgacgttct tcttcggcct ggtacttgta tagttcgata attaagttat taagtaatcg
     9781 acgtaaatta tcatcagtga tacctgttaa cgctggcaaa ttcaaaactt ccagtgtagc
     9841 tttcttcagc tgaattaaat tcatcgtttc tgttagctct ttattatttc gtccaagtcg
     9901 ttttaattct gtcacaacga caatatcacc ttcacgtatg aatttcatca tttcttgaaa
     9961 tccttctcga ttggtatctt tcccacttgc tttatcacta aaaattttat cacactctga
    10021 taataattct aattgtcggt ctaaattttg atctaagctg cttactcgag catacccaat
    10081 tttcgccata ataaaactcc tttaaaattc tgaaatccgg atcattttta aattctgttg
    10141 cccaactctg ttgtcatttt tctagataaa tggcataaat tttcagcgct aagtgacaaa
    10201 agcaactaat ttttcatgat agatttttaa atatctcaat ctatctccaa aattagttgc
    10261 ttttgtagct atagttgact atgaatatga caaataatta gaaaaaactg tgccaattaa
    10321 atataaaaat gacactcatt tacattcaat agaacaccaa gagcccaaca gggtatactc
    10381 tggtgtcctt ttaaaaaagt aactttctga cctaattaat tgagctacta aaaaagctat
    10441 gaaatgagga ataaaaaagg gatcaaaaac ttttaagttt ctgacccttt tgagttctaa
    10501 ttatttcttc cagaacgaag aatgttatct gctttatctg caattgattc tgttagaagg
    10561 actgaaaaat ttatgccagc ccttttgcct agcttatccg cccattgagg aattgttaag
    10621 gtttttctga caagttctat gtctttcaaa tatttggcaa catctacaca gattaaaagc
    10681 atgattttgt atcatagtct attataagag atttaacaat tttttatatc acgaattaat
    10741 aatgaaatta tcattgatag tctttataaa tttaattgtt ctttttcttt actgatgtct
    10801 tccccatcca taatgtgaca ggtaaaatat attccttttt tgtttcttct ttatttattc
    10861 gtttcatcaa aatagcaaca gctgtgtctg ctatatcatt aattggttgt attactgttg
    10921 tcagatctgg taatatactc cgagtcatta aagtaccatc atatccgact actaataaat
    10981 cagctggtac atttaacccc ttttcttttg ctacttgtaa tattagggcc gcatcgatgt
    11041 catttgaagc aaaaatacca tctattttag gataatcctc aaacatttgg aaaaaaatct
    11101 gttttttctt tacataagaa atattgaaat ctaatgtcac agttcgtgga attaactgat
    11161 atgctttcat agtatcttca taggctagtc tccgacgatt agccggagtc tgtaagtcaa
    11221 ttggaccgtt tgtatgaata atattttttg caccttgtgc aattaataac ttggttgcaa
    11281 gttttccacc attgtagtta tcggattcaa caactggaat atcttcattc atcactcgat
    11341 caattgcaac aatcggtaaa ttctgatatt tatattcctg aattccttgg ttatgtgtac
    11401 caacaattaa accatctact tgatcagaca ataactgatt taaataattt gtttcctttt
    11461 ctttattatt catcgaattg cctattaata ccttataacc aatttcatat aacttttttt
    11521 ccaatgcctc aacgagttca ctaaaaaaag gattggctac tgtaggaaat agtaacccga
    11581 caatgttagt tttcttttga aataattgac gcgctacaac gttcggttga taattgagtt
    11641 cttctatagc cttataaaca ttatcaatcg ttttttgact taaatagcca cgattgttta
    11701 atacacgtga aacagttgtt tttgatacat ttgctctttt ggcaacatct tctaattttg
    11761 ggcgcattct cttgtctctc ctaaataatg caataattaa ctatcgaaaa aaagaactct
    11821 atagaactac tatacctgat aatcgatatt ttttctatgt tttattcttg taattgattc
    11881 aagcccaaag caaagtttcc tagtgttgcc gatccattat ttttaattaa aggacgcgta
    11941 atatatttac ttaacggtgg tatttccacg taatcatcca ataatttatt aacattaaca
    12001 cgaatttttt ctaacaattt ttcatttact acgcttccac caaatactat tttatccggt
    12061 cgtataatca atgttgtttg aatcacagct tgtgctagat aataggccat tacatcccaa
    12121 ataggatccg ttaaagaaac gtcttcaccc ttttttccaa aacgtgcttc aaacgttggt
    12181 cccgcaacta agccttctaa acaatcacca tgataaggac aaattccttt aaaatcaata
    12241 tcatcaggat ggcgttttac aaacgtatgg cccatttctg aatgaccaaa cgatcctaat
    12301 agttttccgt caacaacagc tccaccacca acgccagtac caacggtgta ataaactaat
    12361 gaatttattt tttcattcga taaagtggac atgatgtact ctccataagc tgatccgttc
    12421 acatccgttg tccaagacat tggaacattc agctcatctt gtaaataacc taacacatta
    12481 acatttcgcc atcccacctt tggtgtagac gtaatatatc ctgattttgg tgaatttttt
    12541 cgaatttcta ttggaccaaa tgatgcaata cctaatgcat ttatatcaaa ctgtttaaaa
    12601 tagtcaacag tttttttcaa tgtttccctg ggggtggtcg ttggacaaat tatttggtct
    12661 tgtactcggt aatcctcgtc tcccacggca catacaaatt tagtcccacc tgcttctatg
    12721 ctaccaatta acatcataaa acctccttac tcgtaagaaa ttgcatcttt ttttagatga
    12781 taaattgtac tcgagacaaa agcttcttca ctaacactca aatgcatact tggttgattt
    12841 tctgtataat aacgctctgt aaaaacaagc tcgccatcat taataaaaat ctctgccgaa
    12901 cttttatcga taaacactcg aagtgataat ctatcacaca tctgaatggt tccatacctt
    12961 ggatcatttt tgccgttacg agttaaggta cattcatttt tatccttaga ataaaaaata
    13021 ttgattaact cttcatcttt tgtttttaat gaaaatttga cttcttgatt ttttgattta
    13081 gtcaatagta catcaattag agcttctttg aatgaagcat cttgagcgat tattatttct
    13141 cctgccaaat taactgtcgt ttcaacgccg ctgccaactc gaagttgttc taattctctc
    13201 acaggtttca tatacaaacg atctccaatt aactctaatt ctcgaggaag cgttaatgct
    13261 cctgcccatc cgtctacttt ttcaggcata gggctttccc acatatccat ccaggccata
    13321 acaatacgtc taccatctgg agataaagtt gtttgtgttg catagaaatc gtgtccctta
    13381 tctaattcat aaaaatttcc tctaatgaat tttgctgtct cataatcata atcaccgata
    13441 aagtagcctg tttcatatag atttaaataa tcttttccat ttgcttcaat tccctgaggg
    13501 gataataaaa gaatagattt tccatttaat tcaaaaaagt ctgggcattc ccacataaat
    13561 ccttctgtaa gtacttcctt cgctttagaa attggtccaa tgtaatccca atttaataaa
    13621 tctaacgact gataaacaat agcacgacct aatccatctt tttcttgact acccaaaacc
    13681 atgtaatatt tttcatcgtg tttccatact tttggatctc tgaaatgatg tgtgttatct
    13741 tctggtgctt ttgctattac aggatttttt tcatatttag taaagtgaat gccatccgta
    13801 ctatacgcca tgttttgatt ttgccaaaaa tgatctggat cattgtctcc ataatagtga
    13861 tgtcctgtat agaacagata caacacacca tttttttcaa tagcgcttcc tgaaaaacaa
    13921 ccaccttcat cttcttgatc tccaggagtc aaagcaagtg gtaaagattc ccaatgaact
    13981 aaatccttac ttctagcatg tgcccagtgc attggtcccc attcagcact atatggatga
    14041 tgttgataaa acacatgata atacccatca aaatagcaaa atccatttgg atcattaatc
    14101 catcctgatg gtgcagacac atgatatccc aaacgataac gtgtatttgt taattctata
    14161 gctctttttg tcataatata ttcgctcact ttctagataa aattgttttt tattctgttg
    14221 gtttccatta tcctcgaata aatggatccc cttgaacatc tctatcatct tgtttaagaa
    14281 taaagaatgc atatatgcct gctagtaata caataagaga aataatttta aatgttggtt
    14341 gatagccaac gttgtctctt aatattccca atggtgttga taaaatcact tgcccaattt
    14401 gagcagctat ctgaaatcct atcatataga gggttgctga tagctttgta tcaaaatgaa
    14461 gtgtaaaata gcgaaacatt ggtaatgtaa ataatggtac ttctaaagca tgcaacattt
    14521 ttatgcatga aacaaataat ggtgtcgagg caaacccgca caatccaatt cgtacacaca
    14581 taatggttac acctaataac aaagtatttc gaacccctaa ttttctcata atgattggaa
    14641 caattcccat cattaacgct tcacaaaata cttgaatagc attcaatgtc ccatatattt
    14701 tttcaccatt agctgatgtt gaaaacaaac cagtataaaa tcccggaaac atttgttgat
    14761 cgaataccgt ataaaatgtc catgtaaaaa caataaagat gattatcgtc cataattgag
    14821 gcagtttcat tagatcaaac atttctttta aagaaggaat actatttgat tcagcttgtt
    14881 cttgattaaa attttgattt gcttcccgtt caactttagg gttccaaaat aataaattta
    14941 acaatagtaa agaaccaaag aaagatcccg cccaaaagtt taaatgagga ttttttacaa
    15001 ataaaaatcc tgccaaaagc gctaccaagg cataaccaaa tgatccccac gcccttgctt
    15061 gtccatattc aaagccaaat aaacgactaa acctttctga cacagcttca aaaactccta
    15121 cagaagctaa atatccagct gacaaaaata gcgctcccat aataatgcct aaattaaaat
    15181 tgttatctag caatggccca tatatccata taaaaaatgg tccaacaagt gtcgctaata
    15241 cagaagcaaa aattaataaa tttcgtttaa tatacaattt atcttgtaat gttccataaa
    15301 taaacatcaa aattaaggta actaacgaat ttgccgagaa tactgttcct acagcactgc
    15361 cagataaccc taaaccattt gattcagatg ttagccaaag ttgaaaaaat gaccaccaaa
    15421 caccccaaga agcaaaaaat agtaataatg tagctgaact ttgtaaataa gattgatttt
    15481 taaatacgtt aacttttgac atatttttat cctccaacga tatatttgta tcccctttca
    15541 tgataaccgg ttaacatttt tagaaaagga cttgtactcc taaaattata aaagaaatcc
    15601 gcttacatgt caaccggtta ttctatttgg ataatgccat ataatgtcac aggatatgac
    15661 ttttattggt gtgtcgcttt tcttttttaa tggcactatt ttttata
//
LOCUS       DBGZHO010000063        15410 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.066, whole genome shotgun sequence.
ACCESSION   DBGZHO010000063 DBGZHO010000000
VERSION     DBGZHO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.066"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(38..961)
                     /locus_tag="ACN3HL_002251"
     CDS             complement(38..961)
                     /locus_tag="ACN3HL_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HHC8007081.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(1700..2986)
                     /locus_tag="ACN3HL_002252"
     CDS             complement(1700..2986)
                     /locus_tag="ACN3HL_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HHC8007082.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(2979..4247)
                     /locus_tag="ACN3HL_002253"
     CDS             complement(2979..4247)
                     /locus_tag="ACN3HL_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HHC8007083.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            4499..4960
                     /gene="mscL"
                     /locus_tag="ACN3HL_002254"
     CDS             4499..4960
                     /gene="mscL"
                     /locus_tag="ACN3HL_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HHC8007084.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(5019..5465)
                     /locus_tag="ACN3HL_002255"
     CDS             complement(5019..5465)
                     /locus_tag="ACN3HL_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8007085.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(5558..5803)
                     /locus_tag="ACN3HL_002256"
     CDS             complement(5558..5803)
                     /locus_tag="ACN3HL_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HHC8007086.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(5918..6496)
                     /locus_tag="ACN3HL_002257"
     CDS             complement(5918..6496)
                     /locus_tag="ACN3HL_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHC8007087.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(6573..7103)
                     /locus_tag="ACN3HL_002258"
     CDS             complement(6573..7103)
                     /locus_tag="ACN3HL_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HHC8007088.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(7107..7967)
                     /gene="rlmB"
                     /locus_tag="ACN3HL_002259"
     CDS             complement(7107..7967)
                     /gene="rlmB"
                     /locus_tag="ACN3HL_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HHC8007089.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(7960..8355)
                     /locus_tag="ACN3HL_002260"
     CDS             complement(7960..8355)
                     /locus_tag="ACN3HL_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HHC8007090.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(8352..9764)
                     /gene="cysS"
                     /locus_tag="ACN3HL_002261"
     CDS             complement(8352..9764)
                     /gene="cysS"
                     /locus_tag="ACN3HL_002261"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HHC8007091.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(9761..10297)
                     /gene="epsC"
                     /locus_tag="ACN3HL_002262"
     CDS             complement(9761..10297)
                     /gene="epsC"
                     /locus_tag="ACN3HL_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HHC8007092.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(10383..10622)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10619..12079)
                     /gene="gltX"
                     /locus_tag="ACN3HL_002263"
     CDS             complement(10619..12079)
                     /gene="gltX"
                     /locus_tag="ACN3HL_002263"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HHC8007093.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(12249..13406)
                     /locus_tag="ACN3HL_002264"
     CDS             complement(12249..13406)
                     /locus_tag="ACN3HL_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HHC8007094.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(13440..14810)
                     /gene="radA"
                     /locus_tag="ACN3HL_002265"
     CDS             complement(13440..14810)
                     /gene="radA"
                     /locus_tag="ACN3HL_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HHC8007095.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(14873..15400)
                     /locus_tag="ACN3HL_002266"
     CDS             complement(14873..15400)
                     /locus_tag="ACN3HL_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HHC8007096.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         4035 a         3375 c         2774 g         5226 t
ORIGIN      
        1 cctacaagta aacagatgcg taaactaatt tatacgatca ttctgcgtat tgaagagtaa
       61 ggttcacatt ttttggactc tgattgtttt cccctggatt aactggtacg gattctccat
      121 tcgctttgat cgttgcattg cttgctgcac caatcgtgat ggtcgcattt gttgctgttt
      181 ccggtaacac ggtactctgt gtttcatttg ctgccagtgt cccttgataa acataggcat
      241 tgtctactag cacacctaac catacacgat tgacagcagt aaattcaagg gttacaggct
      301 tggtagcgtc tgtgatattt actgcgatgg cactgccaga atcttctcct gtagctattg
      361 ccattttctt ttcttcactt gattttgttg ttgattctac tgtagaagac tctttggtct
      421 gcgtgctttg ctctgaggaa gaggactcct cgactgatcc ttctacttta agcgaagaag
      481 ctgtgtctcc gattattgga tcagcttgac gatcttgcca agtcatatag cccacgacaa
      541 cgacaatcgc caaagcaacc aatcctaata aaatgacagg aagacttgtc caaaagcgac
      601 ttggatgcga ttcttcctga tgcattgctt ttctagaagt acttactgtt tcaggctgcg
      661 gacgttcagg gaccgatcct gtcaatttgc ttttcccatc aaaaacatcg actaaatggt
      721 ctccatcttc tcctacagct tcagcgtatt gccgaataaa tgcccgcacg taaaatttac
      781 caggcaattg gtcaaaatca tcattgtcga ttgcttccaa ataacgtttt tgaatttttg
      841 taatctgctg taattcatct aaagatattt ttttattcag gcgtgcttgc cgtaattttt
      901 ctccgatggt ttcaaaagcc actcgttcat cttctccagt ctgtttgatt ctccgaagca
      961 tctgctgttg caacgaaaga cgttatgttt gggtgctgtg acaaaagtca tgtcacagct
     1021 ccttttttcc gaataaacat tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
     1081 aataaatata agaagctgtt ttttgaactt gttccttgtg actcggagtt aaacggcagg
     1141 ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac
     1201 cggcaaaata taaggagata tttttccgta tgtttctcta atactcaggt caaaacgctg
     1261 atttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagtccaa
     1321 ccaagttaaa aacattaaga agctgttttt acttggctgt tcttattact tgatgcaggg
     1381 cagctttttc acaacctctt ggtacacggt gttccagaag tagcttcttc ggcaataagc
     1441 cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
     1501 gaccacttct gtcacaacct ctttgattac ttcgtttgat tttattttaa tataagttga
     1561 ttaaaagaga gcatgatttg ttttattttc tcactaattt ttccaacaca actaagaata
     1621 ccataaaagc tgattttgga ggaggttcct actacaagtc taaaacgaaa tttaagactt
     1681 ttcctcataa aatactggtt tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac
     1741 ttataaatgc ttccccagct gccagtacgt ctttcatttg gatcgaatcg atgatttcag
     1801 gaagatcaaa taaagttcga tcgccaaata aactttgcgt aaattgattg gcaatatatt
     1861 cgatcgaatt taatgattgg aaatattgtc caagcatttt cttcttcagc aaatcgagat
     1921 ttgtttctga cacttccgga tcatcagcga atccaagaat gatttctttg actttttctg
     1981 ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca
     2041 agctgaattc aaaaccaaag ctgtcatcga taattccttg attgtacatc gctagatagt
     2101 ttcgagaagt attgcctaaa atcatttgga acaacagatt gattgctgtt ttatagcgta
     2161 acagttctgt tccttcttgc ggcaatgtgt ctaatccttt aataccaagt acaaatttat
     2221 ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat ttcttttgtg ttttcaggga
     2281 aataacgtac aatttcttgc tttggaggga aattttttgc ttcttggttt tcccgaataa
     2341 gtttcatcaa tttctcaggc tccatcttac caactacaaa taaaaccata ttgcttggct
     2401 gataaaacgt ccgatagcac gtatacaagt cttgagctgt gattttgtcg atactttcaa
     2461 ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata caagttattt agtatgccaa
     2521 aaaacatccg ccagttaggg tcgtcttcat acatttggat ttcctgaccg atgattcctt
     2581 tttccttgtt tacagtttct tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg
     2641 tcagattctt ttctacctga tccgtcgtag aaaacagata gctggttttc gtaaaacttg
     2701 tgaaagcatt ggcggaagct ccttgtttcc caaataattg aaagacatca ccatcttctt
     2761 tttcaaacaa cttatgttct aaaaaatggg caattccatc tggaactttc accttttctt
     2821 tttcaccata gggaataaat tcgttatcga tcgaaccata attcgtactg aacaaaccat
     2881 atgtcttgtg atagtcattt ttaggcaaca aatacacggt caaaccgttt ggcagtactt
     2941 catgataaag tgtttcattg atttgctcat attctgtttt attcatttgc atttcctcct
     3001 gctaaaaaga agattgcctg caattcgatt tgctcagcta cttgttgtat ctctttgatc
     3061 gttacgctct ccatacgttt caaccattct tcatcagata attttgtttc cggcagccag
     3121 ctgtccaaaa aagaagcttc gattgccgct tgcggagagt ctagagaaag cagatattgg
     3181 tttctcagca ttgcttttgt ctgagacagt tccaactctg ttatttcacc atttcgcaaa
     3241 ctttctaatt gctcgtgaat cagatgaagt acttgatttc ggttcttttc atcgataccg
     3301 gtttggacac tcatgaatcc tcggaacgta tccacgctac tagaggcata ataagctaga
     3361 ctttctttct ctctgacatt catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg
     3421 ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat acacatttgt ctgataagct
     3481 aggttcagct ttgcttgaac gattggctca cgtacttgtc gttccttcac gatattcact
     3541 tgaggttggg tataaaacag atctggataa actgtttccc gcgactcaaa tggtaattgc
     3601 ccaactgctt cagctgcttt gtccggatca acatcgccga caacaaaaat gtcgatttga
     3661 tcatttgcca tcatttcttg atagtaggac gctagcgaac tagcagtgat cttgtccaaa
     3721 tcttcgacta cgcccaaccc tgggatcttt tgttccgggc tgttttcaaa ataaagttct
     3781 tgcaaggcat aggaagcaaa agtttgttta tcttccttca aactttccaa atatagacgc
     3841 agattgttct tttccaagtc aaacgtcaac tgatcaaact gatgattttt aatatttgga
     3901 taaaataaaa cctcttttaa aaaatctacc gcttgagaaa aaaggtttgg atcattgaca
     3961 tattcaccat tcacaaaact gatccctgcg tttagccaat gtaaatttcc tttttttcta
     4021 actgataatc caaagcttgc gccataaagc tctgcaagtt gcgcacttaa ctttgtctga
     4081 tccggataat tcaaactatt tgtttccaac atgctgctga gaagtgaacg tttcgtgatg
     4141 acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt
     4201 gttggtaaga catgaagatt cacgccttct gccaattgat acaccatatt tatatgctcc
     4261 ttttcacagt tgattgcccg cttactcttt taatgggtca acctgccttt tttacttatt
     4321 cctctgcttg aaatttataa gttcaggcaa ttcgccgttt tttctaaatg atgttacact
     4381 ttatagtata gcatagatgt tttttatcaa aagaaacaga cggctaaaag cgtatattgt
     4441 ttttttattt tttatttttc gatatactaa agacaaataa aagaagggag ggtcattcat
     4501 gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt
     4561 tgttattggt agtgcgttta caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc
     4621 actaataggt tggtttgtcg caatgatcac aggtacttct gatttagaag gagcactttc
     4681 aattcttgac tggtcgccga caaaaggcgt cacatttgcg tttggtaacg ttattagtgc
     4741 tatcattaca tttctgatca ctggttttgt cttattctta gttgtcaaag cggcaaaccg
     4801 tgcgaagaat ttacgctcca aagaagagca agtggaagtg gaagaaactc ctactgcaga
     4861 agattatctt agtgacatac gcgatcttct tgccaaacaa gtggcagaag acaatacaca
     4921 tccagtagag caaacaaatc tttccgatac ttctaaataa taaagaatct aaaaaaaaga
     4981 aagccgattt tcagtgtcgg ctttcttttt ttagattctt aacttgctac ttgttccttt
     5041 ttcatgtcga tatgtggaat atcatcttcc aaatacacat ctgagattgc cttgaatcca
     5101 aacgactcat aaaaagcttg taggtattct tgtgcgccga tcacgattgg tttttctgga
     5161 aaatttttct ggatcatgtt aatcgtttct tgaacaatct ttcttcctaa accatcttta
     5221 cggttgtcct gatgaacaag gacacgtcca aaatggatac tctccgcttc ttcatatact
     5281 cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa acgtatgcca agcttgtcca
     5341 tcaatgtcat caacttcttg ataaggacac tgttgttcca caacaaaaac tgcgattcgt
     5401 tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt caaatttctt tacctgatat
     5461 tccactaagc aaacgccccc tgctttttta ttcttagcat accgattcgc acacaaaaaa
     5521 gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta aactgcttca gttaaaaatt
     5581 cgatctcaac tgtccgagta agtacatctg aatagctgta agatactcgt tcaaaagaat
     5641 tttcttcagg atccaaatca acaacgaata ctgaaggata ggtttctgtt aaaacgccgc
     5701 ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa catgattggg ctgccgatac
     5761 gaccttctaa atctttcttg attgaagcta aagttgttgg catacagttc acctctacta
     5821 tcaactatac cacatatttt taaaattttc aagtttacca taaaaaaaaa agaaatgcaa
     5881 taaaaataaa taagaagctc attaagattt ttctaaatta ttcctcatta taaaatttca
     5941 agtgtttttt tattttgagt tttactctcc cgtaagcgct cattacttgc ttgtgatcca
     6001 ttgctaaaca ttcagccatg tctacaaaat caacgccttg catataataa tgaaaaattt
     6061 tagcttctat ttttgaaaac tggatttcgc aattttcgat tgcttctttt aataaaagat
     6121 gctgaatcgc taaaggttct tgcaatgtga tctctgctaa aaagtctggt ccttctgtct
     6181 ctattttttg gtcgattgag acttcatctt tttgatcacg acgcttcagc gcgttctgct
     6241 tcctcaacag agaatagatt tgattgctta taatgctttt ataataactt ccaaagctaa
     6301 cacctttgct tttttcgtaa gttctcaatg cctgatataa agcgatcctt gcttcttgtt
     6361 cccaatcctc agaaacataa tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg
     6421 gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc accattacgt gcagcgcgca
     6481 ataactcctc agacataaaa taattcctcc ataaattcgt ttatggagga atcttatcat
     6541 caatgattca tcgaactgat tagaacgata tgttatttat tttttctcat taaatcgtcc
     6601 aatttttggg acaatttttt taactgctct tcattccatg gagaattacg tcggaaatca
     6661 ataaaatgca tatctttatt ttcttgggct attgtttttt ccgttttttt tatcgtctta
     6721 tataattcat aagcagaagt tcgtaatgct ccttgggaaa agatcatcca ctgttctgct
     6781 aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat tcagctgacc agcgattctc
     6841 tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc
     6901 ttataatttt gttggatgcc cggaactagt tgggcatcga agacaacgat gacttccatt
     6961 ccttcatatt tcgcataatt tgataaacga tgtaaaagag cttctcttgc atccgccatt
     7021 ttgtcctgct ttttaagctg gacaagttcc ggccacgaac caatcatgtt gtagccgtct
     7081 acaatcaaca gctgtttttt catggtctac tccccctgac gttgggaaaa agcctgatac
     7141 ataagcaaac cagcagcaac actggcattt aagctctgga cgtgcccggt catcgggatc
     7201 gtcagcaatt catccatttc ttttttcaat cctggactca ttcctttgcc ttcattacca
     7261 atgactaaag caattgatcc tttggcattc catttttgga agtttgtgcc ggtcatatct
     7321 gtgccaaata cccaaaatcc tgtttctttg agctgttgca cagcttgtac caaattcgtc
     7381 acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag tctttgttac gataggtgtg
     7441 attccaactg ctcggtgttt tggtatgatc acaccatcga cgccacttgc gtctgctgtc
     7501 cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg
     7561 tcttcttttt tctcttttgt tcgttcaatc agttggtcaa gggataaata ttcataaggt
     7621 gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt
     7681 ttaggaaccc atttgactgg cacagcttgt tcacgtgcga tttctttcag ttcttctact
     7741 ttttctcctc gtgaatcttc ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct
     7801 tctactgcgg catggtgccc aaagacgaaa ttatcttcta atgcttcttc attttgatca
     7861 gaaactgact gatttcgtcc agtttgcttt ttatttgaat atctattttg ttttttgtct
     7921 tcaaatccac gtttcgattg atgtttgttt gttctttctt tacccatttt tttcaccaac
     7981 tttctgaata caccagcgga tcaattcttc catccgctcg gtttgttttg tcaaatgcag
     8041 atagcccatg agcgcttcga accctgttgc gacccgatac gtcgtaacat cagcattttt
     8101 tgcgctcgta tggcttttag catttcttcc tctgcgataa taaagttctt cttcttctgt
     8161 caaaagatgt tcttccagca tttgctgaat caaaaaggct tgtgcattcg cagaaacata
     8221 attcgttgcc gcacgatgca gcttattggg ttttgtttct ccttgatcaa tcaggtggtc
     8281 acgaacatag atttcgtaaa tcgcatctcc aacataagcc aaggctaaac cgttcaattg
     8341 tgtgtaatct ctcatgcttc tcttctccat cgggttcctt gcggtgtatc ttctaataag
     8401 atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt
     8461 cttgcttgat ttcgttcttc gatcaattgt tcaatctctt catctaataa ctcttctgct
     8521 gtaaataaaa taccgaagat cgaaagccat tgcgagaata aagcttctcc ttgtgccaag
     8581 acagcggcag aaactttcgg ctggtctaga taagtgttca gccacttagc aagctcatag
     8641 accactgtga tcccatttgc tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt
     8701 tctaaatttt ctaacaaagc gattttatcc gcatcatctg ccaaattctc tgaggcagtt
     8761 tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct
     8821 tctttcatcg tcgtttcact gtagcggatc ggacgacggt attgtgtggt cgccatgaag
     8881 aaacgcaaga cttgtggatc aacgtttttg atcatttcat gtacagtgat gaaattccct
     8941 agagatttac tcattttttc atcgtcttcg ccaatcgtta catagccatt gtgcatccag
     9001 taattagcga attttttccc tgttttcgct tcactttgtg cgatttcatt ttcatgatga
     9061 ggaaattcta aatcttgccc gccaccatgg atatcgatcg tttctcctaa atgttttgtt
     9121 gccataacgg aacattcaat atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa
     9181 gaaatctcgc caggttttgc ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc
     9241 tgctgttctt cccctgtacg ctgacttgct ccgacttcca gttcatcgat ggattggtca
     9301 cttaatttcc cataattttc aaatttacgg gtacggtaat acacatcacc tgaagattca
     9361 taagcatagc ctttttcaac caacacttga ataaatgcta aaatatctgg catatgatcc
     9421 atgactcttg gatgcagtgt agcaggctcg acattcaacg ctttcgtatc ttcttcaaat
     9481 gctcggatga aacgatcagc aacttctggt gctgtaatac ctaattcgtt tgctgtacgg
     9541 atgattttat cgtctacatc cgtgaaattc gatacgaaat cgactttata gcctcgatat
     9601 tcaaaatagc gtcgaattgt atcgaaagca atggtgctac gagcatttcc gatatggata
     9661 taattataca cagtcggtcc gcagacatac ataccgacat gtcccttttg tatagggatg
     9721 aattcttctt tttttctggt caatgtattg tagattttta tcattctgat ctcctcactt
     9781 tttctccttt gattcgaacg acttttgctg gtactcctac cgctgtagcg tcgtctggaa
     9841 catctttcaa cacaacggca cctgcaccga ttttggcgtt ttttccgatc gttaccggtc
     9901 ctaatatctg cgcattcgca gagagcatgg ctccttgttt aacagttggg tgtcttttac
     9961 ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa taaaatcaca tcgtcctcga
    10021 tttctgcggt ttcgccaatg acgattccca ttccatggtc gatgaacacg ccagttccaa
    10081 tcgttgctcc tggatggatc tcaacaccag ttaggaaacg ccagaattga gcattgatct
    10141 tcgccaataa aaagagccgg tgctgatata aaaaatgaga gaaacgatgc caaaacaagg
    10201 catgaaaacc agggtatgtc aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc
    10261 tctttgctgc atcaatcgct cgggtaaacc aactcatgac tttccactcc tttcgtaaga
    10321 attttatgta ggaaatcatc ttcttataaa gaaaagaagc gccttttaaa taagtttcct
    10381 tatcaaaaga cgctttccgc gtggttccac ttttcttcat aatcaatgat tatctctgac
    10441 agctaacgcc tgttatacgt tcttggctac tttgtttcct ataaaacagt ttttcctgtt
    10501 ttctgtgttt cgccaagacc actcccagag gcatttcggc aaccattcat tgataccttg
    10561 caccacccgg tatctctctt gtaatgatca gctgcttact tttttctgtt catcgtgttt
    10621 agttcagtac ttgatttaaa tgtgctaatg atttttcacg accaagcaat tcgatcgttt
    10681 caggcaattc tggaccatgc atttgtcctg atacagctac acggattggc atgaaaagat
    10741 tttttccttt tacgccagtt tctttttgaa cagctttgat ggcagctttg acagttggag
    10801 catctactac ttccatttgt tctagctgtg ctttgaatgc gtggagaaca gtaggaactg
    10861 tttcaccagc aagtacttct tttgctgctt cattcaatac aggatgttca ttgaaaaata
    10921 gcgtagacag atcaacgatt tctgcagcat agctcatttg aggttgatac aggctaacga
    10981 tcttcttcac ccattcgatt gtcttttcat ctgggttttc tgctacacgt ccatcagcga
    11041 ttagataagg cagacacatg tcagtaaatg catctagatc cattgctttg atgtaatggt
    11101 tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg tgatttactt aggcgttttg
    11161 gatcgaacat tttgatcaat tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc
    11221 agcccaataa tgcaataaag ttgaacattg catctggtag atagcctaat tcgcgatatt
    11281 gttcgataaa ttgcaagatt gattcgtcac gtttgcttag ttttttacct gtttcactgt
    11341 tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca gccaaatgct tcatagatca
    11401 tcagttgttt tggtgtattg gcaatatggt catctccacg taaaacgtga gtgattttca
    11461 tcaaatgatc atcgaccgca acagcaaaat tataagttgg cataccatcg cgtttttgta
    11521 tgacaaagtc gccaccgata ttatcggatt cgaacgaaat agcgcctttc accatatctg
    11581 taaatgcgta ttctgtattg cgaggcacac ggaaacgtac aacagattct agaccttgtg
    11641 cttctttttc tgcttgttct tcaggtgtca agttcgcaca tgttcctgcg taatgaggca
    11701 tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc
    11761 atttgtatgc tcgattgcta gcaagcagct gatcaatcag cggttgatag atttctttac
    11821 gttcagattg acggtaaggg ccgtattctc caggattttc aggagattca tcccaattca
    11881 ttcccaacca agcaaggttt tccaactggc ttttttcgcc atcttcgata ttacgttttt
    11941 ggtcagtatc ctcaatacga ataataaagt ctccatcatt gtggcgggca aacaaataat
    12001 tgaataatgc agttcttgca tttccaatat gcaggtgccc agttggactt ggtgcatagc
    12061 gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac tagactttga ctaacagcaa
    12121 aaattccgtc agttacggct tctcaaatat catttattta aagccactca gcacaaattt
    12181 taccttttct aaggtaaata gtaaagccaa ctggttgaat ttccttacca gttggctgaa
    12241 tttctttttt attttgattg tttagtcttt ttctctgtct cttttttatt gtcgattcct
    12301 cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag cagctgtttg aagggcactt
    12361 gttacaacga cttcgatacg ttcattcatg taatgctgtc catcttctac gacaaccatc
    12421 gtgccgtcat caaggtaggc tactccttgt tggcgttctg tcccggcttt tactactaga
    12481 acattcatcg tttcaccagg gatgacgact ggttttacgg catttgccaa cgcattgata
    12541 ttaagaacag gtacattttg gaattcagag actttattca agttatagtc attggttaca
    12601 atgacaccat ctaaaagctt agccaatttg atcaatttgc tgtctacttc actgatatct
    12661 tcaaagtctc catcgtacat ttcgacagat ataccctctt ctttttgcaa ggcatttagg
    12721 atatctaatc cgcgacgacc acgcacacgt ttcaaactat cccctgagtc cgcgatgtat
    12781 tgtagttcgt aaagaacaaa attagggatc atcaaggttc cttctaagaa tccagtcttt
    12841 gtaatatcat aaatccgacc gtcaatgatc acgcttgtat ccaagatttt atatttatgg
    12901 aaattttctc ctgattttcg ttctaacagt tgactctcaa cttgactagc tgtttcttgc
    12961 tcgatttttt tgcttcgtga accaaaaact ttcttccatt cttcgattcg tgtcgttccc
    13021 attctcaatc ccagatagcc taagatgatc atcagtaaaa tcggcaatac actattgacg
    13081 aatggaattt ccatattgta aagaggggtc gagatcacaa cacctaaagt caatccgatg
    13141 atcgcaccga tcgcaccgaa gagaagataa gtcaagctga cctcacttag tttttgttct
    13201 acttgtttga taatagctga gatatgtttg gccaacagca aagataataa aaagaaaata
    13261 agtgcgccta acaggctgtt ggtaaatgta ttattcagcc atccgtttga ctgttgaccg
    13321 attgcctgcc aagctgaggg taaaaatgaa atacccaagc ttgcgccgac aatgatcatc
    13381 agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt ttcgacaatc atttattagt
    13441 tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta ctccaactat ctcgattcct
    13501 tttggcgctt cccagttacc taagttgttt ttaggtaggt atacttttgt gaagccgagt
    13561 ttttggactt ctttgactcg ttgttcaata tgactgacac gtctgatttc tccagtcagt
    13621 ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt tttctttata gcttgaagca
    13681 atactgacag cgatagctaa atcaatcgct ggttcattta attttacccc acctgcagct
    13741 tttaagtaag catcttgatt ctgaagaagc aacccagctc ttttttccag cactgccatg
    13801 atcagagata cccgattgaa atcaagacct gttgttgttc gtttggcatt tccgaacata
    13861 gtaggtgtga ctaatgcttg gatctctacc aaaattggac gtgtcccttc cattgccaca
    13921 acgatagcag agccagttgc accgtctagg cgttcttcta agaaaatctg tgaaggatta
    13981 gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca
    14041 aatcggtttt ttactgctcg caaaatccga aaactatgat gttgttcacc ttcaaaatat
    14101 aacaccgtat ccaccatatg ttctaacatt cttgggccgg cgatcgagcc ttctttggta
    14161 acatgaccga cgataaaaat ggctatccca tttgttttag cgattttgag tagttctgca
    14221 gtggtttctc ttacttggct gacacttcct gccacacttg tgatgtctgg ctgcgtcatc
    14281 gtttggatgg aatcaatgat aacataatca ggggagatat gttcgatggc acgactgatt
    14341 tcgttcatat ctgtttcagc gtatagataa aattctgtgt tgatacttcc gaggcgttcc
    14401 gcgcgtaatt ttatctgctc tgcgctttct tcgccggata catataagac ttttccgcct
    14461 atggctgcta attgctgaga aacttgtaac agcaaagtgg atttcccgat acctggatcg
    14521 ccaccaatca agaccataga ccctggcacc acacctccgc ctaacacacg gttcagttct
    14581 tctaattttg ttttgatccg aggttctttt ttagggacga cgtctgcgat ttttgttggt
    14641 tttgcttttt ctcctgtcaa acttgtccga gttctgcggt ccgttgtatc ttgttcgatt
    14701 tcttcgacca tcgtattcca ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac
    14761 acatacccgc aattttggca aacaaattgt acttttgatt tttttgccat tgtaccgcct
    14821 ccttttatcc taatcatgag acattaaatc aagcttaagt atctttaacg ttttatttac
    14881 tggaagaacc aaatccgcct tgacgttgag cagtcgtttg atcttgatct gcttttaaaa
    14941 acggcaaaaa gatcccttgg ccgatacgct cgcctttttt gatcactaca tccttgaaac
    15001 caaagttggt gaattggaac atgatatggc cttcatttgc ctcattattg taataatcac
    15061 tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac
    15121 ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc tttgattcca gtaggcacga
    15181 gggttggttt caattgtttt tcattttctg atacatcttt tttcaatcca tctgcgactg
    15241 tttccaaccc ctttttccag cctgctttcc agatacttgg aatcacgacc tcttctgctg
    15301 cttcaaaatc atagccagca gcatgatgtg tagcgcgctg cggtagattg atattttgat
    15361 ctttatattt agaaataact tcaaatcctc tttttctcac cggttttcct
//
LOCUS       DBGZHO010000064        14118 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.067, whole genome shotgun sequence.
ACCESSION   DBGZHO010000064 DBGZHO010000000
VERSION     DBGZHO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.067"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..556)
                     /locus_tag="ACN3HL_002267"
     CDS             complement(<1..556)
                     /locus_tag="ACN3HL_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HHC8007097.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACN3HL_002268"
     CDS             complement(572..1051)
                     /locus_tag="ACN3HL_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HHC8007098.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACN3HL_002269"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACN3HL_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACN3HL_002270"
     CDS             complement(2098..3204)
                     /locus_tag="ACN3HL_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HHC8007099.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACN3HL_002271"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACN3HL_002271"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HHC8007100.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACN3HL_002272"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACN3HL_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HHC8007101.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACN3HL_002273"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACN3HL_002273"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HHC8007102.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACN3HL_002274"
     CDS             8175..8873
                     /locus_tag="ACN3HL_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HHC8007103.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACN3HL_002275"
     CDS             complement(9041..11680)
                     /locus_tag="ACN3HL_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HHC8007104.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACN3HL_002276"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACN3HL_002276"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HHC8007105.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="ACN3HL_002277"
     CDS             13523..>14118
                     /locus_tag="ACN3HL_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007106.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DBGZHO010000065        14027 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.068, whole genome shotgun sequence.
ACCESSION   DBGZHO010000065 DBGZHO010000000
VERSION     DBGZHO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.068"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(28..1347)
                     /locus_tag="ACN3HL_002278"
     CDS             complement(28..1347)
                     /locus_tag="ACN3HL_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8007107.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1344..1997)
                     /locus_tag="ACN3HL_002279"
     CDS             complement(1344..1997)
                     /locus_tag="ACN3HL_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HHC8007108.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2285..2805
                     /locus_tag="ACN3HL_002280"
                     /pseudo
     CDS             2285..2805
                     /locus_tag="ACN3HL_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2803..3522)
                     /locus_tag="ACN3HL_002281"
                     /pseudo
     CDS             complement(2803..3522)
                     /locus_tag="ACN3HL_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3473..3682)
                     /locus_tag="ACN3HL_002282"
     CDS             complement(3473..3682)
                     /locus_tag="ACN3HL_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007109.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(3664..3732)
                     /locus_tag="ACN3HL_002283"
                     /pseudo
     CDS             complement(3664..3732)
                     /locus_tag="ACN3HL_002283"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            3959..5232
                     /locus_tag="ACN3HL_002284"
                     /pseudo
     CDS             3959..5232
                     /locus_tag="ACN3HL_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5339..6370)
                     /locus_tag="ACN3HL_002285"
     CDS             complement(5339..6370)
                     /locus_tag="ACN3HL_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007110.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6377..7207)
                     /locus_tag="ACN3HL_002286"
     CDS             complement(6377..7207)
                     /locus_tag="ACN3HL_002286"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007111.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7204..8019)
                     /locus_tag="ACN3HL_002287"
     CDS             complement(7204..8019)
                     /locus_tag="ACN3HL_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007112.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8016..8840)
                     /locus_tag="ACN3HL_002288"
     CDS             complement(8016..8840)
                     /locus_tag="ACN3HL_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HHC8007113.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8830..9930)
                     /locus_tag="ACN3HL_002289"
     CDS             complement(8830..9930)
                     /locus_tag="ACN3HL_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HHC8007114.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10108..10893
                     /locus_tag="ACN3HL_002290"
     CDS             10108..10893
                     /locus_tag="ACN3HL_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HHC8007115.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10926..11309
                     /locus_tag="ACN3HL_002291"
     CDS             10926..11309
                     /locus_tag="ACN3HL_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HHC8007116.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11385..11516
                     /locus_tag="ACN3HL_002292"
     CDS             11385..11516
                     /locus_tag="ACN3HL_002292"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8007117.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11485..11721
                     /locus_tag="ACN3HL_002293"
     CDS             11485..11721
                     /locus_tag="ACN3HL_002293"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8007118.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            11733..11819
                     /locus_tag="ACN3HL_002294"
                     /pseudo
     CDS             11733..11819
                     /locus_tag="ACN3HL_002294"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(11799..12770)
                     /locus_tag="ACN3HL_002295"
     CDS             complement(11799..12770)
                     /locus_tag="ACN3HL_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HHC8007119.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            13404..>14027
                     /locus_tag="ACN3HL_002296"
     CDS             13404..>14027
                     /locus_tag="ACN3HL_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HHC8007120.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLK"
BASE COUNT         4272 a         3035 c         2446 g         4274 t
ORIGIN      
        1 aataactatt gcaaaattat atcttaatta agaaaatatt tttattttaa agataaaaaa
       61 ttcttcatcc tgcaatactt tatattctat attgtaatta ttcagaatat tacttacaat
      121 atataaacct aatccattac tattttcctt atttaaatca aatttaacat caaatatttt
      181 atccatattc gaaattttat tgttaccgta tgaattctct atatataacc aatcattaac
      241 tatcccaata ttaattaccc catttacatc agtatatttt accgcattac taatcaaatt
      301 agatagaata atctttaaag ctgtttttcc tatataaaca ttctcgtcta atatataatt
      361 attgacagtt attttctttt gatttgctaa tatttcatac ttttttaata tgtcttctaa
      421 tgtatcattt attttcaaat attcttcatc attattcaaa ttttctatag aatgaactga
      481 taatatttga gaaatatttt ttgttaaact atcaacgatt tcaatacatt cattaatata
      541 aatatctctt tctttatatt ttccaatatt gtatttcatg ttttccagta ttattttaag
      601 actagcaaga ggggttttaa gttcatggga tgcaccttta aaaaagtcat attttaactt
      661 ttctaatttt aaaatttctt tatttttaaa ttccaaatcg tcaattgttc ttaataaagt
      721 agaatacaaa tcattaattt gttgttttaa ttctccaact tcatcattag agctaacttt
      781 taaactcatt tttttatcaa gtttcatcat tttatcagta acaattttta tttcttgtat
      841 attatttttt attgattttg cataaattaa agaaataata gcagaaaata aaattgatat
      901 taataaagaa tatggtaaaa atttaaggct taaatctttc gcatcttttt gcatatcagc
      961 tgtagaaaca aattgtagat ttgttttttt accatcatta agctttattt ctctttcttc
     1021 aattatcaaa gaattactat cactttctaa attaacattt atattatctt tgatttgtat
     1081 ttcattctta ttattttttt cttttatgaa tacttttatt tcactactct tggaataaaa
     1141 ctccaaagtt tgttctatat attttatttc ttttccattc atattactag aaatttcatt
     1201 tgccatatta tgaatctttt cttttctcgt ctccaaatat gttttaggaa agataaaaaa
     1261 aattaatgaa tgaactaata taattattat tccaagaaca gaaaatattt gtatgaacat
     1321 ttttggaaat atctttaatt ttttcatttt ctctccaatt tatatcctac atttcttata
     1381 gtagttatac agtctaattg taattttttt ctaagttctt ttatatatac atctattact
     1441 cgatcataag gagtttcttc gctatctttc catacataat caataatttg cattcttgtt
     1501 aacacttgtc cattattatc caataaacat tttaatactt ctagttcttt tgcatttaca
     1561 tctatttctt caccatttat tttagctgta tagctattaa aattaaccga tagatcctta
     1621 tattcaaact tctctaaatg tccataattc ttcttaatta aagaatctat tctagctttt
     1681 aagaccggca atgaaaatgg cttttctaca tatccgtcta ctaaattagt aaatgcatca
     1741 attttatatt cttcatcact aaatgcagtc aagattagaa ttggtaaatt gcttttcttt
     1801 ctaatttctt tcaacacttc taaaccattt ataaaaggta tctgaatgtc taagataacc
     1861 aaatttatat cgctattaaa ttttgacaag gcttctcttc catctttagc ttgaataaca
     1921 gtatatccaa attctgaaag atattcactt attccctctc ttatcatatt atcatcttca
     1981 acagttaata ttttcatata tacctccact taagcctata cactagatat tatacagcat
     2041 attatggctc tataatatct agtgttggtg acgccttctg ttgccaatac tttttctttt
     2101 ttttaataaa tgcaaacaga caccttgaaa tcctttagaa aaaaggcttc tataatattt
     2161 tgtgttgttg gaaaatcgaa ggcgattttc tactaacact ttttcttcgt ttcaactcaa
     2221 aaagagactc acttttggta aaatttagtc gaccaaaaca tcaccctacc aaaggagtcg
     2281 ctctatggat aatcatacta gaaaattact cggattaaca gataaacatt tattttttga
     2341 tgaagaatgg ctgattgaaa aagaatataa aggcgttcaa gcgcagttta ttaaagggag
     2401 attggatgac tcaccttccc attgtgaaca ctgtggatcg attcgtatta tccgcaacgg
     2461 ttcctatacg acacgtactc agatgttgaa agtcaaagaa aagttgacta ttttagaatt
     2521 aaaacgtacc cgttttctat gctatgattg tgggcagacc ttttctgcga aaacggactt
     2581 agttgatgaa catcatcaac taacaaagga actgaagcag gcgattctca tagaactgta
     2641 cgaaaatcaa tcacgtaatc tgaaaatcag aagaagtacc gtcggctcaa gcgatattgg
     2701 aaactcttac tcaaagattc cacgacattg gagccgctca aacggcatta tcatcgactg
     2761 tttaaacgac caattagtca aacagaaatc gtcgatgaac cgttgtgcac aatggtgtcc
     2821 tgaacgtaca gcgacacctt ccatatccag agcagtcgcc acatcacggg gatggatgcc
     2881 atccaaatta aaagcaacca cgccagtatg atgttcagga tcttgcggtc cgtaaatggt
     2941 gataccgccg atcgcttgta atttaggtaa aacgtaggca accagttctt gctcataacg
     3001 atgaatattc tccataccaa tctcattcaa gtaatcgatt gctcctgcaa tgttcggagt
     3061 accagcttca aatttccatg gcagctcttt ccatgaacta tcgtaaagat tgacaaaatc
     3121 tatcatttca ccgccgaatt cgactggctc catttgttct aacaattgac gtttgccata
     3181 taatacaccg attcctgtcg gcccgcacat tttatgcccg ctaaaggcga aaaaatctgc
     3241 atccaacgct tgtacatcaa ctgtcatatg cggtgctgct tgggcaccga ctggactatc
     3301 ctcaactaca acagcctgtt caaccctcag ccgtttcaag cacaacaaat aaccttctgg
     3361 atctggtttg ccgacctgaa gatcatcgat cgtcacaaag gaatcaattt tttccttaat
     3421 catcggatgt gcttcaaaaa aatagtctag ctcccgcagt tcagaattga gactactccg
     3481 attttccagt gctgctgatc cgctgctcaa aatgttcagc atccactggt ctcccaaccg
     3541 cttgacttat cccttcataa aaggacagtt ctgctgccgt cccaacacct tgttgatagt
     3601 ctgcaaaagg aattttatag ccgaactgct ccagtaaata ggcttcagta aatagtgatg
     3661 aatactctcg taaaacatcc attcactgtc aatcatcgtc ccatcaaaat caaaaataag
     3721 tgctttggtc atcttctttc ccccttaccc aaaacaagca aaagctgtgt cctgctctct
     3781 ctacagtatc agcataaaaa ctgccgtctg aaaagtcaaa ggtgaaagaa atgtggcgct
     3841 ataatttcta ggactgatag taaatcattc tatcagtcct tttgagcata aaaaaacaaa
     3901 acatacagaa gctccgttag aattgaatca ccacaacaca atcaaaggag cgttctgtat
     3961 gcctgatctt catcttatca aactattact aggaatcaaa gatggaaaca ttcaaatcac
     4021 tcatgtcgag aagaaaaaaa tacattcaat caacagtatc gttgtttctg ccacgctcat
     4081 taaaacgatt cagccctgtc ctcagtgtaa acaggtgaat caacatgggc tgatcgttaa
     4141 gaacggaaag aaaaaatcgc tggtccttct caataagtgt gcgaatcaac ggacttatct
     4201 tgctttggca aagcaacggt acctctgtcg tggctgtcac acctatttta cggcgaatac
     4261 ctacattgtt gaaaaaaact gttttatcgc caaacaagta cattataaaa tattggagga
     4321 attgactgaa aaacaagcaa tgacgacgat ttctaaacat tgcggcgttt cttggtcaac
     4381 cgtttcgcga acactcgctt ctctgctccc catgacaaac gtgaaaataa attggttgcc
     4441 tcgctgttca ttggtagatg aatttcgttc attgaaaaat caagtcggtc cctattcttt
     4501 ttcttgtatg gatggcgata ctgggaaatt actggatatt cttccttcac gtaagaagaa
     4561 agatctcatt tcttatttta tgcaatttga acgacgtgca cgtttaaacg taaaaatact
     4621 cgtaacagat atgaacgcct cttatgcttt gctgataaaa gagtgctttc ctcatgccaa
     4681 actcgttgtg gatcgctttc acatcgtcaa gcacctcatt cgcagtttta aggatatttg
     4741 actatgagtc atgaaaagct tcgaccgaaa cgatccaata caagccaaac actatcgaca
     4801 agtgaaggct ttatctcgac ttctgatcaa acgacaggac acgcttgttt atgataaatg
     4861 gacaaaatgg cgtaattttg gttgggccta tttaaccgaa agtgaagtcg tagaacgtct
     4921 actttctact tctgatgaac tacgaatagc ttatgcttac tatcaagaaa ttcttcaagc
     4981 tttttatgac aaagaagcgg acatcttctt tcagcttgta aaaacaatgc ccaagtcggt
     5041 tccaagagaa ctgcatcata taaaaaaagc gtttataaac tatgaatccg gcattcgttt
     5101 agccttagag ttgccttact caaatggcaa aatagaaaat ctgcataccc acatcaaagc
     5161 attgaaacga atagcttacg ggttaggatg agaaccagaa ttttcttaat caatcatctg
     5221 atcacttatt aaacataaaa aaacatctaa agcagaaaat caattctacc ttagatgttc
     5281 ttatatcact ctatcagtcc tatttgacaa agagccagaa atgtttgccg actatacact
     5341 agctttgttg tgcaaaatgc tgagtatcaa tttccacagg gattgctaga atatctttca
     5401 gctgaatgta taaggcatcg ctaattttct cttcccgatc gttcaaccga tccactaaaa
     5461 tttctttgcc ctccagcgtt tgaaaaacat accgttgaat gttgcctaaa ataaatgatt
     5521 ccttccatag aaccggaatc ttaaccccct gaggaaccgg ttcaaattga atcagctccg
     5581 gtcttaaata ataaatgcag cgattgccct tagcggaaaa ctcgtgggta tactgattca
     5641 gctcatacca ttcgaaacga ttatagttgc cgataaattc cgcaacaaat cggctctgag
     5701 gattctgata caattccttc gaggtggaaa cctgagccac ccgcccagct tccatcacaa
     5761 aaatccgatc actgattcgc atcgcctctt cttggtcatg agtcacaaaa atcatcgtca
     5821 tccctagcga ttgctggata gcgcgcaaat cccgctgcag ctgttttcta attcgggcat
     5881 ccaaagcact taatggctca tccagcagca ggactttcgg ttcagtgacc aatgagcgag
     5941 ccagtgccac ccgttgtcgt tgaccgccag aaagaaactg gacattttta tctgcctgct
     6001 ccgtcatatc caccaatgat agcatctcaa aaaccttttc ctgaatcacc tcaggactca
     6061 gcttctttac cttcaaacca aaggctacat tttcaaaaac agtcatagtt ggaaacaatg
     6121 catactgttg aaaaacaaag ccgatattgc gatccttcgt aggcttatcg gcaatattct
     6181 cattgtccag cacaatctca ccgctctttg gttgttccaa tcccgtgata cagcgcagca
     6241 acgtagactt tccgcacccg ctgggaccta gtaaagtaac cagctcaccc ttttcaatct
     6301 gaatttcatc aatagctaaa atctgttttt catcaaaaaa cagattgaga tcatgtattt
     6361 ctaaaaacat tttccgtcac aactccttta agggcttctt tttcgactgc ttctcttccc
     6421 tcgtctgctt aagggacagc tgttgctttt gtcgataagt cagcataaag gtagttaaag
     6481 caattcccac cataaacagc aaatacaaaa ccatcacagc gctagccaaa tggccgtttt
     6541 cgttcatccg ccgcagcata tagatgcgta ccgtctgaaa tcgaccgcca atcaacaggt
     6601 tcgtcagcat gtactcccca aaaaccgaag aaaaaatcat cagagaaact agggtcacac
     6661 cgatacggat gtttggaaac agcacctgga taataatcgt agacatcggg gcgcccaagg
     6721 tttctgctgc atccactaat tccttcagat taattaagcg catctggttg ttaagactaa
     6781 gatagacaat cggcaacgcc gtaataaaca atgcacctac caacactaca aacattggga
     6841 taccagtttc agcatacgtt cgaagcaaag ccgttaccaa aatcactcct ggtaaagcat
     6901 acggcagcag gagcagcttt tccagccaac gattcaaacg agggaaatac aaatgaatcc
     6961 aaataatggt gggaatcatc aacaacagaa tcgtcaccaa gaccacacct gctaataaaa
     7021 gtgagcgacc caccgcagca ataaattccc tgtccgtcag cagctgttgg aaccattgca
     7081 aggtaaaatc actaggtaaa agcgattttg accatttagt ggagctggca tacaaaatcg
     7141 ttccaataat cggcagcaag taatacagga caaagcagaa caaaatcggt tttattaact
     7201 ttttcacgtc tgcaccacct tgcctttctt ttgaataatc aacattgccg ttaccagcag
     7261 gacacctaaa gcgactgcca acgcactgcc taaattaggc ttggcgaaca catctcccga
     7321 cactaaagcc gcaattcgaa tcgttaaaag atttacatta ctgctggtca gggcatacgc
     7381 tgtttcatag gtccccatgc cattagcaaa taagatgaca aaggtgctgg caatcgatgg
     7441 tcgcaaaaaa ggcaaagcca ccttgaacca agcatacgct gatgaagcgc ccagcaattg
     7501 tgcggactcc agccattcct ttttcacttc cttcatgctg ggatacaaaa acaagacccc
     7561 taacggaatt tggaaatagg tatacgtgat ggtcaatccc caccaagaat acaaattgaa
     7621 gtccgctaga aatggcaaaa tcattttcag cacacctaca ttccccaaca aaataataaa
     7681 agagaatgcc agcggaatcc cagcaaaatt agctgccaaa ttggaaacaa aggtgatttt
     7741 ctcctgcaat ttagtcgata gattcattaa gcataaacat aaaataaacg tcccgattaa
     7801 cccaatcaca ctggagctga cagcaatcag tacgctgtta acaaaggcct gtgtgtaata
     7861 tttgttgctg aaaatatcac tgtaattggc caatgtccac tggttagtta aatcactgtg
     7921 caagctgcac agaaccataa aaagcagcgg cagcagtaaa aatgcacaga agataaagga
     7981 ggcaggaacc agaaccaagc gttttttcat ctctttcatc ccctcatcaa ttcttgaatg
     8041 tcctgcattt tctctgacgg tgcaattcct aataaccagc aaaacaatgg agccgccagc
     8101 agctgtggta cagtttgttc cttcagcttt tggcgtttat ttgaaatcaa ataaaaagga
     8161 acttcacgat gtgcagccaa gctgccgcca tgcagtccgt gcgcatccat cccgtgatcc
     8221 gcagtcacca cgacttgata acctttttgc agccattcag gaaggtaaat agccaataat
     8281 ctgtccgcct gattaaccgc tgctgcatat tcatgagaat cggcggtaaa tttgtgaccg
     8341 acatcatcaa tattcatcga atgtacgacc aaaaagtctg gctgatactg attcactaaa
     8401 taatgggcat ccgcaaataa atgcgaatca gggtaagtgt cctcactata aaagatgcca
     8461 tgctgaatca gtcgctcctc ctgatgctgg atgcgatcaa ccaaacgatt atagggggct
     8521 tgattgtaca actcgctgta ccagtggtaa gcggcggctc ctgtttttcc gccagcttcc
     8581 ttaactaatt caaacagcga ccactctttg gatcgctgag catggtaatt actatagatg
     8641 ccattttcat aggctggaac gccggtcatc agtacttcgt ataacggacg tgaattgctg
     8701 ggcagctcac tttttacctt caataagctt gcttgctggt gctcaactaa atgattcatg
     8761 aacccaagct gggcgacggc tgtgtcgtag cgacagccgt ctagtataac tacaatcagt
     8821 ttgtcaagtc tactttgcat aggtcagtac ctccgcctgc caaagctctg gaagctctac
     8881 agaggtcttg ttccaagctt cattgtcttc aactggcacc gccgcttcat aagcatcctc
     8941 cggcagtaat ttttcagcta cttctttagg cagctctacc ttgcgaatag gtcgcgcata
     9001 gccctttgcc aaattgattt gcccttcatc agataaaata tattcccgtg ctagctttgc
     9061 cgcattggga tgaggggcat ttttattgat taaggttgta tacccgctaa tgatggagcc
     9121 gtctgttggc acagttacct caaaacgctc ggagtcaatt tggtcacgat aatttagtcc
     9181 attgaagtcc caaacaactg ccacatcgat ttcacctttt tcaagatttg ctacgctggc
     9241 atcaacggtg gacaaacggc ctttttctgc catttttttg tagtaattca gacctggctg
     9301 aatatccttt tcgtcacctc cgttggcaat cgccgcagcc aatacagcaa attgtgcttg
     9361 gttggcaatc gtcacatccc ccacgctaac ttgatagtca ccctcttgca gctccttcca
     9421 gctagtcggt gcttgcttca cattctcttt atcggtgata aaggaaatgg ttcccgtata
     9481 gcttaacaac caatccccat catcatcctt tgcccaatcc ggaatttcct cccaatagtt
     9541 ggtcttataa ggtaaggtta actctttgct ttcagccaac ggaccgaagc tgataccgac
     9601 atcaccaata tcggcggttc cattttttcc ttctgattca aacttagcca attcttctgc
     9661 actggacata tccgtatcca cgtgacttaa gccgtattct ttttcaaggt cgttccaagt
     9721 gcctacccaa tttgcccaag tatccggcat tcccaagctg gcaatctctc cttcttcctt
     9781 ggctttttct ataatcgtat ctaaagagtc gtctgccgca gccgattgct tcgttgcttc
     9841 acctgagccg cagcctgtca gcaggatact tactgttgct gcacaaaata aaccgatagt
     9901 catgttacga attttttcat tcattttcat tcattcttct cccctttcga taattccatt
     9961 ctaacaaagc tttgtaatga gagaatcagt ttcttgaaaa ggtttcatga acaatgtaaa
    10021 ggttgtatat ggtttgtaaa tttcgacgaa ttcccgttaa ccttctaaag cttttgcggt
    10081 atgatagtag aaaaaaggag gctccctatg cagtattatg atcagcatct ccacacgtat
    10141 ttttcctttg attcagagga aaaatttgaa aactatttag cctatcagcc ggagtttttc
    10201 gtttctacgg atcactttga tttaaacaat ccatctaccg gaaaagatga cattccggat
    10261 tatccagcct atataaacaa actggactct ttaaaagaaa cctattccac caaatttctg
    10321 cgaggtatcg agattggcgt tgttccagga caagaagagc ggatcgtgga ttacctcgct
    10381 cagcatcctt atgatttaaa gctggtaagt attcatcaaa atggccgctt tgattatatg
    10441 gacgatgtgg ttttaaccaa agatcccatt caaactacca aggaatattt tgatcagatg
    10501 ttgcaggtct tgacggattt tccagaagga gatattttga ctcactttga ttatggatta
    10561 cgccgcttca ccttcacagc ggaagaattc gcggagcatt ttgaggctca gctgctaacg
    10621 attttcaaaa aggttgttga acgagaattg gcgatggagt taaatgccaa gagcttcttg
    10681 aaatacggca acgaagacct ttaccgttat gccgttcctt tgtatcaaag tgtcggcgga
    10741 aagctcttta ccttaggctc ggatgctcat gttgccgaag attatcagct gggctttaaa
    10801 aaaatgagtc agctgttggc agactgtcag gtagaaaagt tgctagtcat tcaaggaaaa
    10861 gaacgccgcc tgacgccgct gccgattttg tgattcctat ataatagaag aaagtggtga
    10921 aaaaaatgag caacctgtgg gactacaatc aagaggcacc catccattat ttaattgcgc
    10981 gacattggga tgcgttgaaa attgaggcgg tttgccgatc cttgttagca gccgttccaa
    11041 aacaacaact ggaaaatttt ttggtggctg acagcttgca gcgggaaaaa gttcaggctt
    11101 attttgcagc ctttaaagat cagcctttgg aatatttgca tgcgcagttt catctttttt
    11161 atcaagtagc cgccccagat gactacaacg atttacgagg acagctgcaa ttgacctttc
    11221 aagcggatga aaccgcctat accgttttat tgggaatggc tcgccttggt gatcaggcga
    11281 aggtcgagtg gcggattttc gatatttgat ggcaggatca aggcgtttca gttgcaaacc
    11341 ttcctctctt tcaattagaa aaaccgcagc aggaagaagt ttgtgtgctg gtcaccgatg
    11401 ctggtgaaat tcgtctccgc ttatttcctg accaagctcc cctggctgta gccaactggc
    11461 gctccctagc tgagcaaggc gtttatgaca acacaccttt cggctcgtgt cattaaggaa
    11521 tttgttattc aaggtggcgc tttggatggt tctggtgatg aagctgtttc cagctatgag
    11581 ggctttttcg ctgatgaagt gcatcgcgga ctttatcatt ttaatggcgc cttggcctta
    11641 ggggaccacg gcccccacac caacggcaac cagtttttta ttgtgcaaaa cacaaaggcg
    11701 caggctgacc tgctaatgta aagcaagcat acttggagct tggaggacta ccggagctgg
    11761 atggtcgtta tactgttttt ggacaggtat accaagggtt agaaatcgta gcagcgatcg
    11821 cagctcagcc gacaaacagt gaagatgtac cgattgagcc agtgttcatt cgacaaatta
    11881 acttcgaaaa aacatcgtaa aaagacactc actgacttca gcaaaagctc tattcttgag
    11941 ctggctgcag ctagtgagtg tctttcattt atccataaga taaagcttgg attcaataaa
    12001 taaataaatg ttttggttaa agctgtgacc agcaaatgag gaaccgtgcg agccagttga
    12061 tctgccaatg caaacatttc tttaggtgaa ggcgctggcg tgtctgccaa cggatactcc
    12121 agtcccaatg cttggtaacc gtgcatacca tagcagtggt acggtagtaa ttctaacggt
    12181 acgaaccgat caagatctgc cacaaaacaa gcaatcgtca gcagctcggt caggttcata
    12241 ttgatacctg gaaccacagg aactcgaatt cgcacttcgc agttaggata ctcaattaaa
    12301 aagcgacgaa tattcttcaa aatttgttgg ttatctaagc cggtccattg tttgtggagc
    12361 ttgctggtaa acatttttac atccacaaac aatgtatcca catagggagc taccttttgg
    12421 atttcattat aagcaccaca aaagctggtt tccagtacgg tattgattcc aatgtatttc
    12481 gatttttgca aaatttcttt agcaaaatcc gcctgaacca gtgcctcgcc tccgctaatg
    12541 gtcactccgc catccgagtg aaagtaaaaa acagcatcct tctcaatctc atccattacc
    12601 tcttcagcgg tcatggtctg gccaaatcct ttttcaatct gcttgctttg tgattcggga
    12661 atcgaacacc aggcacagcg taatgggcag ccctttaaat aaacaacggt ccgtaaacca
    12721 gcaccatcat gtagagaacc ctgttctatt cttaatactg ttccttccat atagattttt
    12781 gaattacaca ctagtttaaa ctaaaacaca caaggaaaaa cttaccattt aatcataaaa
    12841 ttagctcata taaatatact aggatgtaaa atagactggt caaaatctgg tcaaaaaaga
    12901 ggactaatac aggtagtcct cttttttgtt attttaatat tctaaatcat tttttattgg
    12961 tttattccct tattcgatgt agactcaaat cactatatca ctagatatca aacggcgtca
    13021 tacggaatca aaaacatcaa atttgacctg ttaaatggtc attgaataac attcaaaatc
    13081 aataaaacgg agtcagacac ggagtcaaaa acgctgagag taaaaaatat atacagcctt
    13141 gtaggtaaag taccacaggg ctgtatattt tttatttcag attaccttaa atgattccat
    13201 ttacttttta tctcattttt tcctactagt tagtatcaaa tactctccta ttttctcaat
    13261 aaactatttt tggatacatg gtatctgaaa cagctaaaac cttgtcatta cagcaaaaaa
    13321 tcacgttatc cagactgtag acaaagtcca ttttatggat gatgtctaca gtcttttctt
    13381 ttataataga tttatgaaaa cgaatgcaag gagtgatagc tatgatgtct aaaaacaata
    13441 cgaatggtag aaatcaattt gcgatgctta cgattgatga tctagttcct caagatcatc
    13501 tcgttcgaaa gattgatgcc gcgcttgatt ttgaatttat ttatccaatc gtcgaagcca
    13561 cttactccga tttaggtcgc ccaagtatcg atccagtgat tctgatcaaa ttggtgttta
    13621 ttcagtattt attcggtatc cgttccatgc gacaaaccat taaggaagtc gataccaatg
    13681 tcgcttaccg ctggttttta ggctactcct tcgaggagaa aatcccccct ttctcaactt
    13741 ttggaaagaa ttatgttcgc cgatttagag aaacgacggt gtttgaggat atttttgcct
    13801 atattttaga acaagcagtt aaagcaggtt ttgtaacaga ggataatttg tatctggatt
    13861 ctacccacat caaagctaac gccaataaac ataagtttac gaaagaaatg acccatgatg
    13921 aagcgaaagc ctatcaggat gaattagaag atgagatcaa tcgtcaacga atagaggctg
    13981 gaaaacgccc ttttactttg gacttagaaa aggaagtgaa gctgaaa
//
LOCUS       DBGZHO010000066        13943 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.069, whole genome shotgun sequence.
ACCESSION   DBGZHO010000066 DBGZHO010000000
VERSION     DBGZHO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.069"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            137..310
                     /locus_tag="ACN3HL_002297"
     CDS             137..310
                     /locus_tag="ACN3HL_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007121.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="ACN3HL_002298"
     CDS             950..1423
                     /locus_tag="ACN3HL_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HHC8007122.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="ACN3HL_002299"
     CDS             1432..1659
                     /locus_tag="ACN3HL_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007123.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="ACN3HL_002300"
     CDS             2295..2666
                     /locus_tag="ACN3HL_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007124.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="ACN3HL_002301"
     CDS             complement(2922..3164)
                     /locus_tag="ACN3HL_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHC8007125.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="ACN3HL_002302"
     CDS             complement(3196..4098)
                     /locus_tag="ACN3HL_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHC8007126.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="ACN3HL_002303"
     CDS             complement(4111..4299)
                     /locus_tag="ACN3HL_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HHC8007127.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACN3HL_002304"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACN3HL_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HHC8007128.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="ACN3HL_002305"
     CDS             complement(4914..5807)
                     /locus_tag="ACN3HL_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8007129.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="ACN3HL_002306"
     CDS             complement(5885..6808)
                     /locus_tag="ACN3HL_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHC8007130.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPIYFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="ACN3HL_002307"
     CDS             complement(6857..7207)
                     /locus_tag="ACN3HL_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HHC8007131.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="ACN3HL_002308"
     CDS             complement(7240..8142)
                     /locus_tag="ACN3HL_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HHC8007132.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="ACN3HL_002309"
     CDS             complement(8135..8992)
                     /locus_tag="ACN3HL_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HHC8007133.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="ACN3HL_002310"
     CDS             9326..10135
                     /locus_tag="ACN3HL_002310"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8007134.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="ACN3HL_002311"
     CDS             10175..10672
                     /locus_tag="ACN3HL_002311"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HHC8007135.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="ACN3HL_002312"
     tRNA            complement(11057..11130)
                     /locus_tag="ACN3HL_002312"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="ACN3HL_002313"
     CDS             11317..11640
                     /locus_tag="ACN3HL_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007136.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="ACN3HL_002314"
     CDS             11804..12058
                     /locus_tag="ACN3HL_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007137.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="ACN3HL_002315"
     CDS             12128..12373
                     /locus_tag="ACN3HL_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8007138.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="ACN3HL_002316"
     CDS             12449..12814
                     /locus_tag="ACN3HL_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HHC8007139.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..13438)
                     /locus_tag="ACN3HL_002317"
     CDS             complement(12875..13438)
                     /locus_tag="ACN3HL_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007140.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4087 a         2577 c         2302 g         4977 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc atctttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaatatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagcttataa ctattatgcc ttttttaata tataacacag
    13441 ttatttttaa aaataagaat gctaaatcac tctacaataa cggcgaaagc acaaaaaata
    13501 aaaaaattat tacgttatta aaaaaacaga tgaaagatca ggttttatta gatctcattc
    13561 tttcatcact tgaagggatt taatgaacta ctttttcctc tttgtcgttt ttatatattc
    13621 gtattccttc aaacagtagg atagcctctt tcaatgcttg atatttgaac tgtccgttac
    13681 ttaaaaattt agatgtgccg ccctcttcct agaacatatt cttttttact ttttcattaa
    13741 ttgacagacc aatcgaacga aactgtaaat ttcgatagga taatgattgg tcaaactcat
    13801 tcattttcaa gacatctcga ttcatattca agataggaat ctttttatca acatcacttt
    13861 attcgtattt tcctctacca taaaagcttc acgctccaca aaattgtttt atacactact
    13921 attcagccca ttcaacgacc aat
//
LOCUS       DBGZHO010000067        13816 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.070, whole genome shotgun sequence.
ACCESSION   DBGZHO010000067 DBGZHO010000000
VERSION     DBGZHO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.070"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACN3HL_002318"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACN3HL_002318"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HHC8007141.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="ACN3HL_002319"
     CDS             complement(2260..2511)
                     /locus_tag="ACN3HL_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HHC8007142.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="ACN3HL_002320"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="ACN3HL_002320"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HHC8007143.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="ACN3HL_002321"
     CDS             3461..3679
                     /locus_tag="ACN3HL_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007144.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="ACN3HL_002322"
     CDS             complement(3968..4480)
                     /locus_tag="ACN3HL_002322"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HHC8007145.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACN3HL_002323"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACN3HL_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HHC8007146.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="ACN3HL_002324"
     CDS             complement(6933..7376)
                     /locus_tag="ACN3HL_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HHC8007147.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="ACN3HL_002325"
     CDS             complement(7377..8165)
                     /locus_tag="ACN3HL_002325"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HHC8007148.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACN3HL_002326"
     CDS             complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACN3HL_002326"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HHC8007149.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="ACN3HL_002327"
     CDS             complement(9280..9867)
                     /locus_tag="ACN3HL_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HHC8007150.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACN3HL_002328"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACN3HL_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HHC8007151.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11698..12708
                     /gene="gap"
                     /locus_tag="ACN3HL_002329"
     CDS             11698..12708
                     /gene="gap"
                     /locus_tag="ACN3HL_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HHC8007152.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12793..13728)
                     /locus_tag="ACN3HL_002330"
     CDS             complement(12793..13728)
                     /locus_tag="ACN3HL_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8007153.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3811 a         3094 c         2436 g         4475 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagag ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgtaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgtattaat tgaggatgcc gtttcacagc acccctaata aaggaggaac ttttgatatg
    11701 acagtaaaag taggtattaa cggatttggg cgtattggcc gtctggcttt ccgccgcatc
    11761 aaagaagtct cagatgatat tgaagtagta gcaatcaacg acttaacaag tccaactatg
    11821 ttagcacaat tattgcaatt tgactctact catggtactt atcctggcac agttactgca
    11881 acagaagact caatcgtagt ggatggcgaa gcaactcgtg tttatgcaga acccgacgca
    11941 agcaaaatcc cttgggcaaa agaaaacggt gtagatatcg tactagaatg tactggtttt
    12001 tatacatctg aagaaaaagc aaaagcgcat ttagatgctg gtgtcaaacg agtagttatt
    12061 tctgccccag ctggtgctat gaaaaccatc gtctataacg tcaatgatga tacattagat
    12121 gaaaacgaca aaatcatctc agcaggttca tgtacaacaa actgtttagc acctatggct
    12181 tatttcttaa ataatgaatt tgggatcgaa gttggtacaa tgacaacagt tcatgcctac
    12241 acttccacac aaatgctctt agatggacct gtaaaaggcg gtaatttgcg tgctgctcgt
    12301 tcagctgctg acaatactat cccacattct actggtgctg cgaaagcaat cggcttagtt
    12361 atccctgagc tacaaggaaa attacaagga cacgcacaac gtgttccagt cgttgatggt
    12421 tcattaactg aattggtttc agtattgaaa acaaaagtaa ctgctgatca agtaaacgaa
    12481 gcaatcaaaa aacacacagt tgacaatcct tcattcgggt atgatgaccg tcaaatcgtt
    12541 tctagcgatg tcattggaac aactcaaggt tcgatctttg acccaacgca aacagaagta
    12601 acaactgctg gtgatttcca acttgttaaa actgttgcat ggtatgacaa tgagtatgga
    12661 tttacttgcc aaatgattcg cttactagaa aaattcgcta acttgtaatt tgatagatca
    12721 atcgataaaa gaagcctttg actggatcca gtcaaaggct tctttctttt catcccctac
    12781 ttttaaactc gttcaatgaa catattggct taaaaattgt tggactactt gctgatattt
    12841 ttcaggatct gtcttgtatg cttccgcatg ctcggctcct tttacaacat acttttcttt
    12901 tggtcccttc gttgcacgat agaccttatc taacatttca aatggtacaa atgtatcttc
    12961 gtctccatgt ataaagagca ttgggcgctg gtttttcttc aattgttcca ctgcatttgc
    13021 ttcaccgaaa aagtagccag cacggacttt tgtcactaga ctcgttactt gcataagcgg
    13081 aaatgctgga agactaaaca tatcgtctag ctgataagca agctcatcat gaacggaaga
    13141 ataaccgcaa tcttcaatga ttgctttcac attatctggt agtttttctc cgctagtcat
    13201 cataactgtt gctgctccca tgctgacacc gtatagaacg atttcttgcg attttccatt
    13261 gttttctagc actttgttta tccactgtac atagtcttta cgctctggcc atccaaatcc
    13321 aatgtaatcc ccttcgcttt ttccatgtcc tcttgcatca ggaacaagga cattgtaacc
    13381 catatcatga aacatctttg cgtaattggt catcgtttca gcgtttccca tatagccatg
    13441 agccacaaga gctgtttttt cacttttcgt ttcagcagga agataaatcg ctgataattt
    13501 cagaccgtct tttgaagtga tggtccaatc gcttcggttt tcttttgaac taaaccattt
    13561 atgtgcatcc gtttctttgg atgtctgtgt tgtaccaggt gtatcttcgt ctaaaaagtc
    13621 tttctcagaa ggcacaacag cataattata aaaataattc cctgcaaaca ctaacgcaac
    13681 aatcagagct aaagcgacgc ctaaaaggat tttcatccaa agtttcataa atcatccatc
    13741 tcatttctct tttttcatat aaccttgaat tagtataatc aaagaatctc tactatgcaa
    13801 tgttcatttt tataac
//
LOCUS       DBGZHO010000068        13705 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.071, whole genome shotgun sequence.
ACCESSION   DBGZHO010000068 DBGZHO010000000
VERSION     DBGZHO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.071"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..902)
                     /locus_tag="ACN3HL_002331"
     CDS             complement(<1..902)
                     /locus_tag="ACN3HL_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HHC8007154.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="ACN3HL_002332"
     CDS             1185..2153
                     /locus_tag="ACN3HL_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8007155.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="ACN3HL_002333"
     CDS             2266..2544
                     /locus_tag="ACN3HL_002333"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8007156.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="ACN3HL_002334"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="ACN3HL_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HHC8007157.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="ACN3HL_002335"
     CDS             3001..3756
                     /locus_tag="ACN3HL_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HHC8007158.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="ACN3HL_002336"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="ACN3HL_002336"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HHC8007159.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="ACN3HL_002337"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="ACN3HL_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HHC8007160.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="ACN3HL_002338"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="ACN3HL_002338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HHC8007161.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="ACN3HL_002339"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="ACN3HL_002339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HHC8007162.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="ACN3HL_002340"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="ACN3HL_002340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HHC8007163.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="ACN3HL_002341"
     CDS             8493..9035
                     /locus_tag="ACN3HL_002341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HHC8007164.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /gene="atpA"
                     /locus_tag="ACN3HL_002342"
     CDS             9058..10614
                     /gene="atpA"
                     /locus_tag="ACN3HL_002342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HHC8007165.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="ACN3HL_002343"
     CDS             10628..11530
                     /locus_tag="ACN3HL_002343"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HHC8007166.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="ACN3HL_002344"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="ACN3HL_002344"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HHC8007167.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="ACN3HL_002345"
     CDS             12973..13395
                     /locus_tag="ACN3HL_002345"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HHC8007168.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4530 a         2452 c         2988 g         3735 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatttggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctgcttcg ccgtccacca
     9901 ggtcgtgaag cttatccagg ggatgttttc tacttacact cacgcttatt ggaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgtctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaaata attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgttgctc agccgtcctg ttaagaaaac gggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca actactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttacaa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatcg
    13561 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg
    13681 gaataaggga ctgcgacaag acttt
//
LOCUS       DBGZHO010000069        13146 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.072, whole genome shotgun sequence.
ACCESSION   DBGZHO010000069 DBGZHO010000000
VERSION     DBGZHO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.072"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="ACN3HL_002346"
     tRNA            complement(77..149)
                     /locus_tag="ACN3HL_002346"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="ACN3HL_002347"
     CDS             530..1099
                     /locus_tag="ACN3HL_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HHC8007169.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="ACN3HL_002348"
     CDS             1086..1946
                     /locus_tag="ACN3HL_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HHC8007170.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /gene="yycF"
                     /locus_tag="ACN3HL_002349"
     CDS             2136..2840
                     /gene="yycF"
                     /locus_tag="ACN3HL_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HHC8007171.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="ACN3HL_002350"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="ACN3HL_002350"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HHC8007172.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /gene="yycH"
                     /locus_tag="ACN3HL_002351"
     CDS             4677..5993
                     /gene="yycH"
                     /locus_tag="ACN3HL_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HHC8007173.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="ACN3HL_002352"
     CDS             5994..6863
                     /locus_tag="ACN3HL_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HHC8007174.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="ACN3HL_002353"
     CDS             6918..7727
                     /locus_tag="ACN3HL_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHC8007175.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="ACN3HL_002354"
     CDS             complement(7830..8459)
                     /locus_tag="ACN3HL_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HHC8007176.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="ACN3HL_002355"
     CDS             8629..9921
                     /locus_tag="ACN3HL_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8007177.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="ACN3HL_002356"
     CDS             complement(9997..10659)
                     /locus_tag="ACN3HL_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HHC8007178.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="ACN3HL_002357"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="ACN3HL_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HHC8007179.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="ACN3HL_002358"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="ACN3HL_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HHC8007180.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattc
//
LOCUS       DBGZHO010000070        13135 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.073, whole genome shotgun sequence.
ACCESSION   DBGZHO010000070 DBGZHO010000000
VERSION     DBGZHO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.073"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..456
                     /locus_tag="ACN3HL_002359"
     CDS             <1..456
                     /locus_tag="ACN3HL_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007181.1"
                     /translation="AERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEH
                     KNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKS
                     YGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            517..1986
                     /locus_tag="ACN3HL_002360"
     CDS             517..1986
                     /locus_tag="ACN3HL_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HHC8007182.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            1997..4201
                     /gene="topB"
                     /locus_tag="ACN3HL_002361"
     CDS             1997..4201
                     /gene="topB"
                     /locus_tag="ACN3HL_002361"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HHC8007183.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4217..4366
                     /locus_tag="ACN3HL_002362"
     CDS             4217..4366
                     /locus_tag="ACN3HL_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007184.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4440..5033
                     /locus_tag="ACN3HL_002363"
     CDS             4440..5033
                     /locus_tag="ACN3HL_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HHC8007185.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5049..5948
                     /locus_tag="ACN3HL_002364"
     CDS             5049..5948
                     /locus_tag="ACN3HL_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HHC8007186.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            5951..6436
                     /gene="ssb"
                     /locus_tag="ACN3HL_002365"
     CDS             5951..6436
                     /gene="ssb"
                     /locus_tag="ACN3HL_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHC8007187.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6802..7062
                     /locus_tag="ACN3HL_002366"
     CDS             6802..7062
                     /locus_tag="ACN3HL_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007188.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7503..7709
                     /locus_tag="ACN3HL_002367"
     CDS             7503..7709
                     /locus_tag="ACN3HL_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HHC8007189.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7709..7960
                     /locus_tag="ACN3HL_002368"
     CDS             7709..7960
                     /locus_tag="ACN3HL_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007190.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            7975..8412
                     /locus_tag="ACN3HL_002369"
     CDS             7975..8412
                     /locus_tag="ACN3HL_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007191.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            8405..9112
                     /locus_tag="ACN3HL_002370"
     CDS             8405..9112
                     /locus_tag="ACN3HL_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007192.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            9277..9477
                     /locus_tag="ACN3HL_002371"
     CDS             9277..9477
                     /locus_tag="ACN3HL_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007193.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            9493..9672
                     /locus_tag="ACN3HL_002372"
     CDS             9493..9672
                     /locus_tag="ACN3HL_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007194.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            10013..10276
                     /locus_tag="ACN3HL_002373"
     CDS             10013..10276
                     /locus_tag="ACN3HL_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HHC8007195.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            10270..10620
                     /locus_tag="ACN3HL_002374"
     CDS             10270..10620
                     /locus_tag="ACN3HL_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HHC8007196.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(10644..11258)
                     /locus_tag="ACN3HL_002375"
     CDS             complement(10644..11258)
                     /locus_tag="ACN3HL_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007197.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            11572..11994
                     /locus_tag="ACN3HL_002376"
     CDS             11572..11994
                     /locus_tag="ACN3HL_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007198.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            12004..12207
                     /locus_tag="ACN3HL_002377"
     CDS             12004..12207
                     /locus_tag="ACN3HL_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007199.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            12418..13002
                     /locus_tag="ACN3HL_002378"
     CDS             12418..13002
                     /locus_tag="ACN3HL_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007200.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         4754 a         2142 c         2625 g         3614 t
ORIGIN      
        1 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
       61 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
      121 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
      181 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
      241 catttgaagg atgcggcgtt tattgaagat ccacagcata atcaagtaat tttaaaagga
      301 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
      361 tcattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
      421 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
      481 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
      541 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
      601 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
      661 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
      721 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
      781 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgagacagaa
      841 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
      901 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
      961 gctgaactaa agccgaaaca tgaacggcaa aattttttag ttggagacga ccgtttagat
     1021 catgcggttg cttttttatg gaaagatcca cagacaggag agacagtagg ggcaagttat
     1081 caaggaacga tcgtcgattt taatcgtttc ggtaaacggg gaacgtataa acacattgac
     1141 aagaatccta cgccaaatca cggatttaat ttaaaaatag gcgatccgaa gcatttaaaa
     1201 ttctttgaaa gtagtattga tctgttaagt tacgctgcat tgaatcggga gaaactacaa
     1261 gatgcctggt tagtttcgat ggacgggtta aaacatcatg taatcagtca ttacgttgaa
     1321 gagtcgattt ctgaattaag acgaaaacaa acatttcctc aatcgattga aatatgtgtg
     1381 gacaatgatc gtgcaggaca tattttttat gaaaaagaac agatgaaggg aatcgttgat
     1441 ccttttacca ataagaaaat ccgttgtgag cgaggaattc caaatgattg gcaagtacct
     1501 aaagaataca aagctactta tgaagcagtc gcaaaagaaa tgagtgttga acctgaagca
     1561 attatggcca tacacaaaac tgaaactaat ttacagctga caaatcaatt ggtgtctgct
     1621 catgatgttc aatctacgtt tggaaagatg ttggcgaagg gcgaaccagt agaaacaatt
     1681 gatttgaaag aagcatgtac cacggtcgcg aaggaactga aagtatgtga acgcgcagat
     1741 ggaacataca actttgatcg tttttatagt agaaaagcca acataaaaga cgttaatgca
     1801 ggaatccttc tttcctataa agcagaacaa tactacaaag gctataaaaa gcatgaacat
     1861 gaatttgtac ctgaagtgaa aaaggattgg aatgatcaat tgaagcatga gatccagcaa
     1921 caagaaatca gaaagcaaaa acgtgcgatg ttgtttcaac aaggcagaca acaagaaagg
     1981 gagtgaagtc gtcactatga aaaccgtcat tttagcagaa aaaccgtcac aagcgaaggc
     2041 ttatgccgat agcttttcta aagctacccg aaaagatggg tattttgaga tccaagatcg
     2101 attgtttaca ggagaaactg tgatcacgta tggttttggt catttagtcg agttagattc
     2161 gcccgatatg tacgatgaaa aatggaaaca atgggcatta gaacatttgc ctattttccc
     2221 caatcaatac cactatcatg ttcctaaaga taagaaaaag cagtttagtg tcgtcaaacg
     2281 acagctgcag tcagctgata cgattgtgat cgcgactgat agcgatcgtg aaggggagct
     2341 gattgcctgg tcaatcattc aacaagcagg cgccaatcaa ggaaaaacct ttaaaagact
     2401 ttggatcaac tccttagaaa aagaagccat ttatcaggga ttccaacagt tacgagacgc
     2461 agaagagacc tatccaaaat ttgaagaagt acaagcacgt cagatcgccg attggttaat
     2521 tgggatgaac ggtagcccac tgtatagttt actcttgcag caaaaaggca taccaggaag
     2581 tttttcttta ggtagagtcc aaaccccaac actctatatg atttatcaat tgcaggaaaa
     2641 gattagaaac ttccaaaaag aaccatattt tgaaggaaaa gcccaagtaa tcgctcaaaa
     2701 tggcgcattt gatgcgaagc ttgatccaaa tgaaacccaa gcgacacaag aagcatttga
     2761 agcctattta aaagaaaaag gtgttcaatt aggaaaacag ccaggtacga tccttcaagt
     2821 cgaaacagag aaaaaaagtg cggctagccc acgtcttttt tctttatcga gccttcagtc
     2881 taaaatgaat caactcatga aagctagtgc caaagatact ttggaagcca tgcaagggtt
     2941 gtatgaagga aaatatctaa gctatccgcg aacggatacc ccttatatta cggaagggga
     3001 atatgcgtat ctgttggatc acttagacga atacaagcat tttttaaaag ccgaagcgat
     3061 tccgactcct attcatacac cgaatagtcg gtatgtgaat aataagaaag tccaggaaca
     3121 ttacgcgatc attcctacaa aaacggttat gacagcagcg gcttttgaac aactaagtcc
     3181 actgcagcag gccatttatg aacaagtgtt aaaaacaacg gtggccatgt ttgcggaaaa
     3241 atatacctat gaagaaacaa cgatcttgac gcaagtccag cagcttcagt taaaggcaat
     3301 cggaaaagta ccgatagatc taggttggaa gaagttattt ggcaaagaga acgacggaaa
     3361 agagaaggaa gaagagccgc tacttcctaa agtgacaaaa ggagaaatgg tgacggtaga
     3421 tctacaagtc cttgaaaaag aaaccaagcc accacagcct tataccgaag gtacgttgat
     3481 cacggcgatg aaaacagctg ggaaaaccgt tgatagtgaa gaagcgcaat ccatattgaa
     3541 agaagtggaa ggaatcggta cagaagcgac acgggcgaat attattgaaa ccttgaaaca
     3601 aaaggaatat atcaaggtag agaaaaataa gctcgtggtg acgaataaag ggattttgct
     3661 ttgccaagcc gtggaaaaag agccgctgct tacgagtgcc gaaatgaccg ccaaatggga
     3721 aagctacttg ttaaagatcg gtgaacgaaa aggaacacaa accacttttc tagccaatat
     3781 ccaaaaattt gtctctcact tattggaagt cgtaccaggg caaatccaat ccactgattt
     3841 tggatcgacg ttacaagaag tgaaagcagc cagtgaaaag caagaagccg cgcgtcattt
     3901 aggaatttgt ccaaaatgcc aggaacaaga agtcttactc tatcaaaagg tggcagcatg
     3961 tacgtctgaa gcctgtgatt tcaaactatg gacaacgatt gccaaaaaga aacttacagc
     4021 gacacagctg aaagagatca ttcaaaatag ccgaacaagc caaccagtga aagggttaaa
     4081 aggtcagaag ggttcgtttg aagcaacgat tgttttaaaa gaagacttca ctacaggctt
     4141 tgaattttct gaaaagaaaa aaacgaactt caagaaaaga acacgacgca ctacaaaata
     4201 atggagggtt aatcttatgc gtaatacaac acacaaacaa caagaaatcg aaaatcaaaa
     4261 agccaaaatt cgttcagaac aggaaaaaat gcgtgccagc aaacgaagac tgcagcaatt
     4321 gaagaaccag cagcggattc aaaaagaaat cgaattagat cgataaattc ctttcttgtt
     4381 aatataaaac taacatgtta tagttgtgtt agttttatat taactttagg ggaagagtaa
     4441 tgaaagacaa aatccaatgt atttttgata aacataatgg caacctatcc ttgaaggatg
     4501 ctagaagtga aggattatcg cctatgacgt tagatcgatt agccgaaaag gataaaatag
     4561 aaaaggtagc accaggtttc tataccttaa aggatgcgtt cgtggatgaa ttgtatctcg
     4621 ctcagagtat ctattccaga gggatttttt ctcatgagac tgcgctcgat ctttttcaag
     4681 taggaacata tatccctaaa aagatcaata tgatgtttcc taaaggatac aatgtatcaa
     4741 aggagaaatt agatcagtat gccattcaac cgcattacac taataaagaa aattttgacc
     4801 tgggagtcac agaaacagaa agcttttacg gcaataaaat tttagtctat gatttagagc
     4861 gaacgttatg tgacatgtgg aatccaagat acaaagcaag cgtagaggta aaacaagaag
     4921 cattaaaaga atatatgaca agtaccagta gaaatacaaa taagctaaga agatacatgg
     4981 atattttaaa atcaccaaaa gaaatgactt tgtatatgtt gccactttat tgagaggagt
     5041 aaagatgaat gacaccgaca caatttaaag agaaaacaag aaatttcgca gcagagaaac
     5101 atttaaaccc acaaattgtc caaagatatt atatgatgga aaaattatta gaatgtattg
     5161 ttgaatcgcc ttatcatgat gattttgtat taaaaggggg atttctgatt ggatcaaaat
     5221 acgggttaga aaaccgttca accgttgata ttgatacgac ttatcgaaat tcgaaactaa
     5281 caaaagaaaa gttagaaact gttttttctg aattaacagc taatcctaca aaagatggaa
     5341 ttcgttttga attaaaggga ttaacagaga cgagggaagc cgattattat ccaggttttc
     5401 aagcaaagtt tattgcttat cttgaaaatg cacgtgtacc ttttaaatta gatattactt
     5461 caggtgattc tattattcca gcagcattga tgtatgaaca caaattaatg tttgaagata
     5521 aaacgattca tattccagct tatcctacgg aacaaattct agctgaaaaa ttacatgcca
     5581 cgtttagttt tggaaaagat aattcgcgca tgaaagattt ttatgacctg tatatgattc
     5641 cgaaattaga acgtatcgat gagaaaaatt tgtataagag tgttcaagga acattcaagg
     5701 aaagaaataa tcaatcggtg tttaagcatt tgtatgatca ggaaatgcct caattggtga
     5761 aagatgaggg cttgagagaa aagtggaaaa gataccaaca agaaaactat tttgccaaag
     5821 acatttcttt cgaatctaca ctaacttccg ttgattccct gatgcaatca attgtagagc
     5881 aagagaaggc agaacgaaaa caaaatttta agagatcaca acaaatgaat caagaaatgg
     5941 agagataaag atgatcaata atgtaacttt agtagggcga ttaactaaag atccagattt
     6001 acgttatacc gcaagtggca cagcagtggc gactttttcc ctagccgtta atcgtaattt
     6061 cacgaatcaa aacggcaatc gagaagctga ttttatcaat tgcgtgattt ggcgcaaacc
     6121 agcagaaacg atggcgacat tagctaaaaa aggcagcttg atcggcgttg tcggacgaat
     6181 tcaaacacgg acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc
     6241 cgataacttc caactattag aaagtaaagc agcgacagaa agccgtatgc acgctgatca
     6301 atcgtccagc agtccaagcc ctaccacctt tgaacaacgg gatacagcga cgcctaacaa
     6361 caatggattg aacgcttcac agaatccatt tggtggacaa tcaatcgata ttagcgatga
     6421 tgatctaccg ttctaagtag cattttctat tggttgcatt tgctacggtt tatgttataa
     6481 tttagacaac aaaaagaatt ttcaatctat aaccaaaaac cactagctgg cgggctagtg
     6541 gctttctttt acgtttctat tataagaatt aacgggtagg cttactgtct ttcttggcaa
     6601 atttacaatc aagccatttg cagatatagt gcgcggctac ttctgccatg attgcaaaaa
     6661 caaaatcaaa aagaattttc aaacctataa cctcctcccc ttgccagatt aggccggggt
     6721 agcagacagc aagactatta tagcataatt gaaatatcca aatgattgga tttttgctat
     6781 aattttagcg aggtgattgt gatgaacaaa tatgttggtt tgcttgataa aatccgagta
     6841 ataaaaacgc aaccgttatt ggttcgcttt actttacaaa cgattcatga atcgattaat
     6901 tgtgtagttg cagatattga aattatcgat aaattgctaa ttatggatga tggaaaatac
     6961 aatattgccg tcacaggtca cttcaataaa cgaaatcagc tagttattgc tagcatgtat
     7021 gttagaaatc ccgatcattt tacgcgatcg atgggcatat aaataaaaga agagttgtag
     7081 tcctaaatga ggattgcagc tctttttgtt ttacatagaa acaggaaaag acctttttag
     7141 gaagacacaa gtgccttctc aattgaaaaa cctttctctc actccaaccg ccaccgccgt
     7201 tcgagaagaa aggaagtgaa cgctgcacgt tcactaagat atggtgtctt gcaaagcaag
     7261 acaaaataga caaaacttcc tctcaccaaa aggttcgttc ctgttcgtta tctctttatt
     7321 gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag gacaagggta
     7381 aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gatttattct ggccaacaaa
     7441 tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa
     7501 acatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc ccaaactatc
     7561 atgcaccaca tactgttgaa tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc
     7621 gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc gattacattt
     7681 tgattgatga gaaaggaaag aaacgctgat gaaaacacaa cacaaattat tgactgtaaa
     7741 agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag cagaagcttt
     7801 acttattccg cggtactgga cgatagaaac ccctttagta gaggatgcac cgactatgct
     7861 atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa acatggaaac
     7921 ttatgaaatc gaatattggt taaccaaatt agagaactaa aaaggagaaa aaatatggct
     7981 caaaattact atgacgaatt tgtcaaatta cctttggata aaatggcaca aaaaatggag
     8041 gatatgacgt tcctatacca tgaaacacgt gtacccaaaa aacattacaa ggaaaaattg
     8101 tcagtcgcag tggaagaaat gattgaatca ggtgtcgaaa tgaatctcat tgcgacgtac
     8161 tatcgaacac tggaagaact gaaaaaacaa aatggaaaat ggtttttcca agccttacta
     8221 tgcttggaag taggtgtcaa accaagcact atcaaacctt ccgaatatca agccttagaa
     8281 ctgacttatg caaaattcgc acagattaag aaagctaaag caatggctag cgactggcta
     8341 gatacttttg aaagtatcga aaaaaatggt gcattttata cgattgaatc ggaggagaaa
     8401 gataatgaat aaggtggttt atcagctaac aacagaagat gtttcgcaat ttttaacaag
     8461 caaagaacac ttgaatgaag taatcagacg gattcaaaaa gactttagtt gtatggaaga
     8521 aatgaagtac tttattcaaa gagtggaaga acagttgtat atggaaagcg aaacaagtca
     8581 aacgaaggtc acagtcagcc ataatcattt agacgtgtat aaacgtcgtc ctgaaacggt
     8641 aaaaaaagga acagagcttc tacgactaga aacagaaaaa tacatcatga atgtgtacct
     8701 agaaaggagt gagctggtcg aaaactttgt cagctacacg atttgtagga aacactatta
     8761 ctcagaatca gaatattatt caattttcga gagcatggaa ttaatggaag aagaaatgga
     8821 agagctaaac agcaaaaatg cgacggtaga cgattattac cttgtattta ctaggttttt
     8881 gacgtgtggg acggaatcta tcgtgttaat gggaatggat tatgaactcg ctgtacccga
     8941 agcatttttg agggaatatg tagaagaagt agataaccca ggcgacgact ggtacacgac
     9001 tttaactgat tttttagaca cctacactta cgacgataca gaagaaatcc aaaatgaact
     9061 tgaccgtaaa cgaatgccat atcaacgatt tgaaaggaaa aaaggtaaat aaccatttat
     9121 accgaaaagt gaggatgtgt gaaataagaa caaaaaacct tgaaattaag ggaatggttc
     9181 ttatttcgca ccaatcgctc caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc
     9241 aaagcccgat aacctaagag aaagaaggag atccatatga ataaaatcat tcctctattg
     9301 ttcgtactgt ttgttggcga gatacttatg cgtcatgctg cagctgtaca tttaaacttc
     9361 gtagtattct taggaatact ggtattttgt ttgatctttt ggcgatttgt attagccctt
     9421 gtgagtctac tattcaagat gattgcagcc atatttttca tagggttatt tcgatgaaag
     9481 gagagagtac taatgccaat tgcaatagga aataaacggt tacccgtgac attagatgaa
     9541 aagagacaaa aagaattgca gcaactaaag cagaagtacg gaaaaagtga atctaagatt
     9601 atgtgtattg cgttagatct attgatcgcg caagaaaaag caggatttga tataccagca
     9661 ctaaaaaagt gacgtcactt ttcatttgaa gaaacaaaag tgatagcact taattgttcc
     9721 tactatttag aatattttct atgtcctttt tattccattt tgtatcaata actatgaaat
     9781 ctttaaagta tccagaagag attattttta gatcaatttt tttcttacct gattctaaag
     9841 attttgtttt cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca
     9901 tagtttatgg attcatggaa tgttaatcta atttaataga aaaggataat taagtatata
     9961 cgttttttct tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat
    10021 gttacctata aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga
    10081 atatcttgga attcatacag aagacaaagt gaagataata caagaagaag taaacggtca
    10141 gaagcggcta attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt
    10201 tgaaaattac actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg
    10261 taatgaaaaa tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct
    10321 cgatctggac acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt
    10381 gcggattata gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg
    10441 ctatatgtaa atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat
    10501 caactaacga caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat
    10561 agtttagttg aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa
    10621 aatagaaaca gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta
    10681 tatacggttt gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt
    10741 tttagatcct caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca
    10801 ctgtatagct taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt
    10861 gcctgacgtc gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg
    10921 atcaaatctt taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt
    10981 agacttgtga tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc
    11041 tcgtcgtaat ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg
    11101 acgaaatcca gtgcttcttg aaaaacaagt cgatgagtaa tcgttgcgcc agattgtttc
    11161 tcaatgaaaa ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt
    11221 tgatcgatgg atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa
    11281 ctatttaaaa aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt
    11341 gtctagttag ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc
    11401 acttttcttt ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac
    11461 gattatgaca ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt
    11521 aagatttatt aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat
    11581 aagtttattt tatctttagg tattttaact attggaatta gtgtaactgg aactacaatt
    11641 cctacatttg ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta
    11701 actcctttag ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact
    11761 gaaaattatt taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg
    11821 acaggaacga tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat
    11881 tggaaagaaa aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa
    11941 tcagctggaa acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt
    12001 tttatgccag aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa
    12061 attaatttac cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa
    12121 aaaattcaaa aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac
    12181 caaaaaacat atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc
    12241 tttttttcta attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc
    12301 tttatttttc aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc
    12361 agttaaacta tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg
    12421 aaaataggat acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc
    12481 ctaaataaat ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat
    12541 cgaccaggat tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg
    12601 cgcttagatc gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat
    12661 gagcgtggtg tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct
    12721 acaggacagc tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc
    12781 ctggaacgat ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt
    12841 cctgaaaaat tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca
    12901 cctattaaga ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg
    12961 gcaaaaatgg aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct
    13021 gaaaattttt gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc
    13081 tactgataac ttattctcaa atgttgtaag gattttattc atttgttaat attaa
//
LOCUS       DBGZHO010000071        13052 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.074, whole genome shotgun sequence.
ACCESSION   DBGZHO010000071 DBGZHO010000000
VERSION     DBGZHO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.074"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(28..2067)
                     /locus_tag="ACN3HL_002379"
     CDS             complement(28..2067)
                     /locus_tag="ACN3HL_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HHC8007201.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFINNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2125..2682)
                     /locus_tag="ACN3HL_002380"
                     /pseudo
     CDS             complement(2125..2682)
                     /locus_tag="ACN3HL_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(2830..2996)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(3221..3427)
                     /locus_tag="ACN3HL_002381"
     CDS             complement(3221..3427)
                     /locus_tag="ACN3HL_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007202.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(3443..4057)
                     /locus_tag="ACN3HL_002382"
     CDS             complement(3443..4057)
                     /locus_tag="ACN3HL_002382"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HHC8007203.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(4204..4887)
                     /locus_tag="ACN3HL_002383"
     CDS             complement(4204..4887)
                     /locus_tag="ACN3HL_002383"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HHC8007204.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(4996..5454)
                     /locus_tag="ACN3HL_002384"
     CDS             complement(4996..5454)
                     /locus_tag="ACN3HL_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HHC8007205.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(5538..7301)
                     /locus_tag="ACN3HL_002385"
     CDS             complement(5538..7301)
                     /locus_tag="ACN3HL_002385"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HHC8007206.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(7522..8982)
                     /locus_tag="ACN3HL_002386"
     CDS             complement(7522..8982)
                     /locus_tag="ACN3HL_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007207.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(9190..10116)
                     /gene="glsA"
                     /locus_tag="ACN3HL_002387"
     CDS             complement(9190..10116)
                     /gene="glsA"
                     /locus_tag="ACN3HL_002387"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HHC8007208.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(10139..11566)
                     /locus_tag="ACN3HL_002388"
     CDS             complement(10139..11566)
                     /locus_tag="ACN3HL_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8007209.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(11597..12811)
                     /locus_tag="ACN3HL_002389"
     CDS             complement(11597..12811)
                     /locus_tag="ACN3HL_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HHC8007210.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         3751 a         2720 c         2177 g         4404 t
ORIGIN      
        1 cttttactgt acttaaaaag caatttttta ttgataattt tggttgaggt attgcaatag
       61 ttccgatgct cgtttggttg ctgaatcatc atcttcttta ttttccaaca tgctgaccat
      121 catataacct tggttatcaa gattgaaagc aaacaagaaa ctgttctctt gcccctttac
      181 atcctgtttt tctttgattt ccgctgtacc agttttcgct gccaacggaa tccctaaagc
      241 agaaagagaa tgtgctgtac catttacatc ttgcacaact tctctcagat ctggcacgat
      301 cgtttgtact gctgtttcgc tgatgacatt cttcttatct tttgtctctt tatctgcaat
      361 caatttagga tagacaagtg tgccattgtt gataaaaaca gaatacattg ctgcttgctg
      421 gataggagta attagaagtt cgccctgtcc atatccagta tcagctagca agatatctga
      481 gttaaagcta tcttcattag aaatttgtgc tggattcata ctaattggca aatcaaggtc
      541 ttcaccaaaa atgaatttat ctaagcctgt acgaaatttt ttctcaccca ttttcaacgt
      601 ttcttgtgcc gcatatatat tatcggaata gatcaaagca gtttttaagt ctacttgtga
      661 tacatcacta ctgacacgcg ttgttttaaa agatccccaa gaactgtctt tttgccattt
      721 aagcccgttg atcgtcaaca cttcatttgg atcgatagtg ccgttgtcga gaccgattgc
      781 tgctgtaatc attttaaacg tagatccagg agcataacct gtcgcaaatc ggctgatgaa
      841 tggatgttca ggattttctt cataagcttt gtaatcttct tgtgagatcc cgtttgtcat
      901 tttgtttgga tcatagcttg gagagctagc aagcgcaaga agatcaccgg tttttggcgt
      961 tgtcgcaaca gttgatgcag cttttcctcc tagactgtca aaagctattt tttgtgcctt
     1021 cgcatcgatt gtcaatttga tatctttgcc attttgaact tcatgttcga tcagaacttt
     1081 tttctctaca ccgtctgcat ctgtaatgct taatttccca cctgttgtcc cacgaagatc
     1141 cttatcaaaa gccatctcca aacctgagcg accgattttt ccattactgc ttaattctgg
     1201 attcttatca atatcttctg ctgtgatatc tcccacgtaa ccaatcagct gagcagctgc
     1261 ttcacccaaa ggataatatc tgccgtctac ttcttgaatg gtagctccag ctggaagttc
     1321 tggcgttgct ccatcaatga ttttcaatgg gacaaagtaa tcgggttgta cccagctttg
     1381 tgaaatcgcc tgattgatag catcttctgt taagtcgaag gaggaagcaa tcgctttgat
     1441 attggctgtt ttttcgcctc catctccaag tttacttgga acgactccta attgttttag
     1501 tttgcctgtt gttgctaatg gttcaccatt tcgatctata atattccctc ttgctgcttc
     1561 ttgtgtggtc aggcttactt tgtcatttcc ttccatttct ggaaaaacca agttgggttg
     1621 ccagttgatc gtggtttgac catcatttct gtctaatgtt cctttataag aaagatcttt
     1681 caattcacct aatgaggtat tcatctttgc tttatatgaa aaactgtaag tagaatcgtc
     1741 ttttttatct acttttagat tcgatatctg aagtcctttg acatcagcag caccgtatat
     1801 attctggtat ttatctaaga tctctttttc agataatgca cttttatttg ccgccttttt
     1861 tgatgtcatt tctgcagctt tgttataatc tcccttgttc aaagcttgga caaattgctc
     1921 aactgtcttt tctccagctt ctactgcttg ggtttcttga tagtgctggt agtaaaaata
     1981 accgccaccc gcagctgcta ttaagatcac tgcgccggca atataagcgc ctgttcgatt
     2041 tttgccgtgc ttgtcacttc ttttcatttt ttcctccttc tcttgcttgt cattccttta
     2101 tttcactatt tatacctgtt tattctaaca tatgtctttg aggaaatcca taccacaatc
     2161 cagaagcaca ctttctggaa ggttcgtttg gatactacca agtaatttcc caaccgcttt
     2221 gggtagcttg aatattgaag ttacgtcttt cagctgctga gagatagctt tgatcacttg
     2281 ctgctgcctt ctgatcctcc cgaagtctcc ttctttgtct tcccgaaatc gagcatactg
     2341 gagtaaagta ttaccatcca tcacttgctc tcctttgttt atatatacgc catctaaatc
     2401 tagagatttt tctgcatcga tcttgactcc accaggaaac agttcattaa cgcaatcgat
     2461 aaaatcttga aatgtgatac ttgcataata gggagcttca aatttgaaat tttcctttaa
     2521 tgtttgattt aataaatcaa ctcccccata agagtaagct gcatttatct tattcattcc
     2581 gtaacctgga atatcgacat atgaatctct catgatagag atcagttttg cttgttgtgt
     2641 tttctggttg tattgtgcaa ccagaagtga atccgagcga cctccaccaa tcgatctttt
     2701 ttcaccgcat ctcctcctca cacagcaatc cacttgtcag gtgaggagcg agtttgtctc
     2761 atcaaataag tcagtcacaa aaatataaag aaaaggtcag aaaccttttc gaacaagaat
     2821 tctgacctag catcatctca tcgtccgagt tttagcacta tacaacgtaa agaaaacatt
     2881 cttagctatt ggaaaaagcc ttaatccaac agtttctgtt ttacccattg gcgactttcg
     2941 acgtttctgg gcaacagcct atgtttgtat aggagcctca cctaacaagg ttattactat
     3001 attctattta cgagttcatg atagactttt cctaatgatt aggcaatgga atttgaaatg
     3061 aaatagtgaa atttaacaat ctttaatatt ttttagaaaa aaataacaaa taagttgaaa
     3121 gaatcccgtt gcaaattctt tcagttgcac caggattctt tgataatttt ttagttttat
     3181 gtgttttttt atatgttttt tcacttttcg gaataaatat ttatttgtta aagtaattaa
     3241 acaatccgct aatcgtttga tctggcattt ctatttcctt accatctaaa gtaacagtag
     3301 taacgacaaa atggtcttgc aatggcggaa cttctaagta ctgcccttgc agaaaatcat
     3361 tcactgtttc atattctttt ttcatttctt ttgaatctgt cgatggttta tagcttattt
     3421 ttaacataac tagtgctcct ttttattcgg gacgtgcaat cgtgaaaatt tctcctattg
     3481 ctgcataatc atttcctgcc aaacggctta cagcattcaa ttttcttgga tcgatccttc
     3541 ctgtcttatc atcatagact gtttcattta aatgatattt ctgtacttct agcaaaaata
     3601 aatcagctgt tactttattt ttattccgta tctcgacatg ttcatataag gatgtttcaa
     3661 aacgaacttt tgcttctgtc aatgctggta ctgaaatgat tactgaatca gttaaagtca
     3721 agtcagtcag gtacagttcg ctttcctcat taggcagatt ggctgctgtt ttatttactt
     3781 cttctacgtt gtcctcatca aggatatgga taacagcttc tcttgtctca agaatattct
     3841 ttgctgtgtc ttttactgca tcttgttttc tctggatcgc caaggataag atgggtcgat
     3901 tcgaactgac gatattgaag taactgaagg gtgcgatatt cactatatct tttgctgatt
     3961 tagtcgttac tactgctact ggtctaggga tgactgaacc aatcagcaac ttgtaatttt
     4021 cacgttctgt caattctgaa ggactccgtt caaacatggt ttcgccttct ttctataaaa
     4081 ttcgttaaaa agcagatctt gaagacaaaa tgaaaagtaa tgcttttttc atcttcttag
     4141 aatctgcttt aaactatcta tcaatttttc ttttttgtca agaatctgtg ccgtgcgtgt
     4201 tttttagtta tttgctttac ttgcggcttc gacatatctt ttagtgatca attgcggacg
     4261 ggtgataata gatccaacta cgactgaaaa agcacctaat tcatatgctt tctctacttg
     4321 ttcaggagag tcagtatgtc cttccataat tactgggata tcgacttgtt ctatgatttg
     4381 attcaataaa tcaaaatcag gtgtctgcgt ctttcgtgaa tattctgtat agcctgctaa
     4441 agtcgtagac aaaagatcaa aaccatcttc ttgcgcttga agcgcttcct caaaagtcga
     4501 aatatctgcc atagctaacc gaccgtgttc gtgaatcatt tggacaagtt cagcagttgt
     4561 tttttctgtc ggacgtttac gagaagttgc atccagtgca atgatttctg cttgcgtctc
     4621 caaaagttct tccacttctt tttctgtcgc agtaataaac acttctgacc catcgtaatc
     4681 tcttttgata atccctatta ccggtaaatc aacgattcgc ttgatttcat tgatatcttc
     4741 tgtcgtattt gctcgaatac caactgctcc gccttctttt gcagccaaag ccattctccc
     4801 cataataaaa gaactgtgta gcggctcgtt ttccaaagct tgacaagaaa cgacgactcc
     4861 gcctttgatt tgttccagtg tatccacaat atctcctcca gtaatgttat ataaaaatac
     4921 agcttcatat aaaaatgtaa cccttttcta ttcaggagac aataatgagc tatttctttc
     4981 agcagacctt tcttactaaa agaaaattac ttcaaattct tcgtatacga ccagcttctc
     5041 ttctgtaaat tctatgttca acgcttcttt ataagcatgt ttaaaaaact cagcatggac
     5101 tttccgccaa taagctaatg tccgatcccc ttctccttct ttccaagcat gctctttcgt
     5161 gacttcacta aaaggcaaga tggtcacatt tatatttttg atgatacaaa ctggttcatt
     5221 ttttccattc aggaccacgt ctaattgacc aacttttggt aaaggctcat tctcttgttt
     5281 atacagatcg taaccacttg atgtaccagt ctttatcttt tttacaacta gttcgctcaa
     5341 ctcgtctgcc attttttctg tatccccaaa tgaaaagaaa cctaattttt ctgattgata
     5401 actaggatat ttttcttgga actttttgac atattcttct acttgctgat acataacatc
     5461 cacccctttg ctttttataa tgaaaaaacc atccagatac tagtataaac aattatctgg
     5521 atggtgagca taatgaatta ttgaatattc aagacacgca gactatcttc aacgatttgt
     5581 tttggtgtta aatgataacg ttcataaagc tgccctacag gaacgctatc cgtgaattct
     5641 ttctctgcac caaaatttaa tacgttcatt gaagaatcac cataataacg actgatattt
     5701 tcgccaaatc ctcctgacaa actaccatct tctaatgtga tgactaattc gtgtgtttct
     5761 tttaatttat ctaatgtttc tacgtcattt tctgtgatcg ttcctggatt gatcaacgtt
     5821 gcttcgattc ctttttttct aaaagctttt actgtttctt ttcctaattc aagaaaaccg
     5881 cctaaagcta aaattgctac ttttcctcca ttatttactg tttgataggc tggaatacta
     5941 taatcatttg cgatagctgt accatgttct acaccatgtg taggaattcg gattgctaca
     6001 ggctgcgctg tttgttcgaa cgcccaatct agcatagaga tcatatcctc ttttgttgct
     6061 ggagcaagat atttgatgtt cgggatactt gataagtaag gaatgtcaaa tgttccttgg
     6121 tgtgttcggt cactagctga gatcgttccg ccaccgacta aaataatcac tggattctcg
     6181 ttgatcgcta aatcatgtga taattgatca tatgcccgtt gcaagaaagt acttgattgg
     6241 aagacgactg gacgtactcc ctgagaagcc aaagcagaag cgaaagtgat agagtgctgt
     6301 tcagcgatcc ccacgtcaaa ataatgatct ggatgttttt cttggaatgt tttcagtcca
     6361 aaggcgcctg gtatcgctgc attgactgcg gcaataggag ctgtacttgt ttgcattttc
     6421 ttatccaaat aatccatgat gatcatatta aatgtttctc cagaagttac ttgctttgcc
     6481 tccccggtgg acagatcaaa tggtacatgc caatgatatt tcattttatt atcgattgcc
     6541 ggctgataac cgcgaccttt ttccgtatgg acgtgaagta caatcggatg atcaatatct
     6601 tttacttctt caaataaacg gatcaccgtt tccagatcgt ttccattatc cacgtaacga
     6661 taatcaaatc ccattgcttt aaataggtta ttgctgcttt taccgttggt ttgacgaagc
     6721 tcagctaagt ttttatataa actgccatga ttctcatcaa tagacatctc attatcgttt
     6781 actaatacga ttagattgga ttgtaaaaca ccaccattgt tcaatccttc aaaagctaag
     6841 ccaccactta gggagccgtc accgataaat gctaccacat ttcctgattc tttcttcaga
     6901 tctctcgctt tagctaaacc tgttgctaag ctgatagatg tagatgtgtg ccccactgta
     6961 aaatagtcat gtttactttc atgttggttg gaatatccgc tcacttcacg gtaatgtcct
     7021 ttttcaaaac cattttttcg accagttaaa agcttatgac cataagactg atgggaaaca
     7081 tcccaaacga ttttatcctt tggtgaatca aatacataat gaaacgcaat cgttaattct
     7141 actacaccta gattcggacc aacgtgccca cctacatcgc tgtccttttg caagattttt
     7201 tggcgcatct cttctgccaa ctgtttcatt tcctcaacag ataatttttt gacatctgcg
     7261 gggctattga ttgcatccaa tacatgtaat actgtactca taatacattc tctcctccgt
     7321 actatcttct tttaatgaaa atagatttgt tacactttat ctattctact acttagagtt
     7381 gactctaagt caatagcatt ttaaaaaaat ttcagagaaa gcttgttata taagtagatc
     7441 ttcgcacgaa tcaggactca aataaaaacc ttctacagac aattaaaaag ctttgtagaa
     7501 ggtctcctaa ttaaggtctc atcaagaaat atgttttttt aataggtgaa gttcctgagc
     7561 aatatgatac aaatggatgt ttgcaccttt taatgagatt ggatagatct ttgtcttttc
     7621 agtttctaat ccattttgat agctagcagc atcgcacaaa accactcttt ttttcgcaca
     7681 tagacattca tcaggcaatt cttctaatga acgaaataaa ataggattta tttcagcgat
     7741 gccttcttcc gcatacaaat gaaattgggt tcgataaaaa aattgtttga ctgaactttc
     7801 tgaaacaaca aaaatttcta tttcctgtct ccccgcttgt tcactgttga tcaaagaaag
     7861 acttttgacg aattttcgaa tgaaattttc attccatctt agttggattt gatttttctt
     7921 tttccactct tccaatattt ctacaatttt tccgtacaga agttgttctt tttctgatag
     7981 aagatagatc ctttccggta aaaatacttg tccatctgcc cacaacgtac ggacaaattg
     8041 taaaaaggat tgcttgaaaa taaaattttc tgcatcgtcg atttcagcga tactaataat
     8101 ctgtaaaatc aattcattca gtgataggtc attgagaaca aaatttttat aaacaacttc
     8161 gaaatctttt cttaacagct ccatgttctc attggtataa tttctactgt tgaacaaaga
     8221 aaaaatataa tagacatctt cttcttgtaa gtctagaatt cctttttgct cttccaatcc
     8281 ttgacagact aattgaaata acggcttcgt ttctgcgctt ttcttatctt cttctttcag
     8341 tccaagggga aatgcctttc ttccgattgc gatctctatt cctcgtatga taaaggactt
     8401 ttcatcttcc gaatatcttc ttttaaaaaa atgagtctct acataatcaa tcaactcgtt
     8461 acaagcttct tctacatacg gatttttatt ttcatagcct tcccaattga cataacgtac
     8521 taaagctagc aagatgttcc gcgagtcaaa ttctgggata atgatttctt tatttttcaa
     8581 ataatcattt tctttaaaaa aatccaatac gatttttttg attgtatata ctttgctcaa
     8641 agaaataaat tcaagatcag ccagttctgt actcgtgaat ataccattaa aataataact
     8701 taaaaacttt aaaaaataag attgaccgta cagaaactgt gtgagctcag aaagagcaat
     8761 accatgtttg aatacgagtt tatacttatg cttctctctt acttgttctt ttatacaata
     8821 ttctagacac tcggctagac tttctagatc gtgaaggatc gttggtgtag tcacccttag
     8881 agaaatagct gtttgttcga tgtctatttc ttggaattca aataattgtt cacacagata
     8941 cacttttcta aatatatttc gctcgatgta attttccagc attcctgata cacgcctcca
     9001 gtttttctta tgattttatt taatcatatc tgtaaatcgt atttttgttt cctttttatt
     9061 tagaaaagcc ctttcaaaaa ccaataaaaa aagaaactgg gacaaaagtc aaacaagctc
     9121 acaatttcag cctcattgta ggtagctttg agccgtttgg acttttaccc cagcctcttt
     9181 caagaatggt tattcaaaga tgtcagcgtc tagttctttg actacatctt tcaacaattg
     9241 gataccagct gcgctgttac caaatggatc tagtgccggg ctgaagacac ctatgccgta
     9301 acgatttggc acagctgcca tcaacccgcc gcctacaccg ctttttgcag gtacaccaac
     9361 atggacggaa aactctcctg attcatcata caaaccagca gttgtcataa ttgatttgac
     9421 gattgtagca ctttcttcag taatgatttg tttgccattc caaggagcaa ttcctttatt
     9481 tgccagcaca gcagctaatt ttgctatgcc tgtagcggtg acattgaggg agcattgtct
     9541 gaaataagca tcgagtatct ccggtacgtc tccttcgatc atttgattac ctttcatata
     9601 gtaagcaaga gagcgattga tatcacctgt tcttgattca gaatgataga tttcttcatt
     9661 caatgtgata ttaggatcat cacagatctc tttcataaat gacaagattc gctcaaattt
     9721 ttcatctgca tctttaccgg caatcaacga ggttgttgca atcgctcctg cattaacaaa
     9781 aggattcatt ggatgtttgc gatgattgat ttccatattc atgatagaat tgaaggcaaa
     9841 accggttggt tccgtgttga ttgtttgaaa gactttttct attccgttgt ctttgattgc
     9901 taataacaat acgggaactt ttgacatgct ttcgatggca aagcgcacat cggcgtctcc
     9961 tccctcaatc agttgttttg tatccaaatc ataaatcgcc atacctaatt gtttgggatc
    10021 cacttcagct aatgctggaa tgtaatccgc cacttgtcct gtttgataat agtggaaatt
    10081 ttttccaatc aattgttcta attcttttac ttccatttga ataaccagct ttcatttttt
    10141 atttttctgc atgctggaat ttatgacggc atgcgtagat cgtaaatgga ataactaaga
    10201 cgataagata agaaacaatc agaatcgttt cataaatccc atgctgtcca gctgcgatac
    10261 tagcaggtgg aacaaatgag atacaaaaag caaaaagtga agtcaaaaga cctaaacaag
    10321 caacgattac ttttacaact tttccgcctg gaacctgata ggctctttca agactgtcat
    10381 ctttaaaaac cagcttcaaa tagcccgcga aaaacataaa gtacaacatc aggtagatta
    10441 caacagtcaa tgacatcgct gcaagaaatg aaagattatt ccccccgccg cttaatgtaa
    10501 agacggctgc ccagattgtt gcaacgatcc catttgcgat catcaaatga gcaggaacac
    10561 cgtgtgtgtt ttcttttgca aaatattcag gaagtaatcc ttcttctgct gctacgtgaa
    10621 gtgcttttga aggagaggtt acccaagaag caatttctcc gatgacacct aaacaaacaa
    10681 gaatcgcaag aattttcgca atccatgcaa gatttggatc aatgtgtctt aataggaatt
    10741 ctaacgattg aatcacccct gtattaagag acaaaccatg ttgaggtact gtagtagcga
    10801 cggtcaatcc gccaaaagta tctaaaatga ttgccagaat aaccaataca aacattgcta
    10861 atggataatc ctttttaggg ttttccattt catttgcatg actggcagat gtttctacgc
    10921 ccatatatgc taaaataaag gaaacaaaaa caaccagcgt aggcaatttc gaaaaatcag
    10981 gaatcaatgt tttcatagac agtatcgttt gtagtggagc gcctgaagcg acataatgga
    11041 tccctaagcc aaacaagact aatgctggca acaagatacc agctacaaaa ccgatccgag
    11101 caatcaatga agtgtatttg gttcctttta actgtgagag taaaatagcc cagaaaataa
    11161 tcaataggat tgccaatttc agatatttat tgttttgtat agcaccaata cccgttgcat
    11221 aggataatgc accagttaag aaatacagca tggtcaagta gccaactgtt atctcaaacc
    11281 attggaaaaa gattgcggca aaaccgaatc gttttcccaa tgtgcgactg acccaagtat
    11341 agacaccgcc tttttcccat cctttcaccg ttgccatctc tgctgcgcac aatgccacag
    11401 ggataaacca tagcaaaccg cctaataaca agaaaaatac taagctgaag cctgaggtcg
    11461 cgaatgtggg atattcatat aatgaaacga ccattgagat ggtcatagcc aaaaagccaa
    11521 agaacgttaa tttttttgca ggaattttcg ttttgctttg ttgcatgaat cttcctcttt
    11581 tctatttgaa tttgtttcaa ttgagtttgt tgccaaagaa gaaaaagtcc aatccttctt
    11641 cttgttcttc ttttgtagta gtgatcgttg taaagtgcat cgccgatttt aaaatcactg
    11701 ttgtcagcac ataggcatac acggcagtaa tgatgacacc aatcacttga atccctaaga
    11761 agtaccagct gcttggattc gttagtaaat ggctgttaga tgcaaagatc cctatcagaa
    11821 tcgtacctgt gaatccgccc atgccatgaa caccccacac atcaagtgca tcatcccatt
    11881 gtttcttttt acgaaaatca acagcagcat gacagacgat acccgcaatg atcccaatca
    11941 gcatggcact ttttgcttct acataaccgg cacaaggcgt aatggctgcc aatccagcaa
    12001 cggatcctgt tagtacgtcg acaaaatcaa agccatttcc ttttactttt gcaatgatca
    12061 gccaagtaat catcgcaaat gcaagagcga tgaatgttga accaaatgca ttgactgctt
    12121 gttcatctgc tcgaagtgca ccaccggaat taaaaccgaa ccagccaaac caaagcagtc
    12181 ctgtaccgat agcagctgcc ataagactgc tatgctgact tctttctcct aaaggaatct
    12241 ttctttgacc aagtgtgagg atacatgcta aagagccgaa tccagctgtc gtgtggatga
    12301 ctgctccacc agcgaaatct ctaaatccca tctgatccaa aaatccgcca ccccatatcc
    12361 agtggcaaac agggaaataa atcagcagat tccaaaaaat aacaagtata atatagcctt
    12421 ttaaattcaa tctccctgca aaagctcctg tcatcaaagg aacggtaatc acgataaaca
    12481 tcagttggta aagaaagaac attaaaaatg gaatcgttgc accatgaaac atgttgggga
    12541 agcttgtaac atgtctcatc aaaaagaaat ctgccgggtt tccaataaca ccgccgatat
    12601 cccgtccaaa ggccaatccg aatccaccaa atacccacat aatcgttgtt atcccaacgg
    12661 agagaaaaga ttgagacatg atcgttagta tattattctt ccgtgctaat ccgccgtaaa
    12721 aaaaagctag accaggagtc atcaggcaaa ccattgctgt acataaaatc atgaatgctg
    12781 tatctcctgt attgataggt aatgtattca tttttttcgc ctcctttcta cgattacgag
    12841 tataaaagaa ggtgtagttg tttttttctt ctgttttttt gaattaatac ttgcatttat
    12901 aaaagacaga caattaataa aagcttgatg tgttgtgctc tttttcgttt ttcacacaaa
    12961 taaagacaaa aaataaacgg tcttcttttt atagaaaacc gtttattttc gtcttttttt
    13021 atttttaaag atattttttc ataaggaata aa
//
LOCUS       DBGZHO010000072        12873 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.075, whole genome shotgun sequence.
ACCESSION   DBGZHO010000072 DBGZHO010000000
VERSION     DBGZHO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.075"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            68..502
                     /locus_tag="ACN3HL_002390"
     CDS             68..502
                     /locus_tag="ACN3HL_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8007211.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(580..1113)
                     /locus_tag="ACN3HL_002391"
     CDS             complement(580..1113)
                     /locus_tag="ACN3HL_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HHC8007212.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(1207..2385)
                     /gene="mutY"
                     /locus_tag="ACN3HL_002392"
     CDS             complement(1207..2385)
                     /gene="mutY"
                     /locus_tag="ACN3HL_002392"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HHC8007213.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2378..3175)
                     /gene="recX"
                     /locus_tag="ACN3HL_002393"
     CDS             complement(2378..3175)
                     /gene="recX"
                     /locus_tag="ACN3HL_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HHC8007214.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            3282..4664
                     /gene="rlmD"
                     /locus_tag="ACN3HL_002394"
     CDS             3282..4664
                     /gene="rlmD"
                     /locus_tag="ACN3HL_002394"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HHC8007215.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4838..5416)
                     /locus_tag="ACN3HL_002395"
     CDS             complement(4838..5416)
                     /locus_tag="ACN3HL_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HHC8007216.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5738..6208
                     /locus_tag="ACN3HL_002396"
     CDS             5738..6208
                     /locus_tag="ACN3HL_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HHC8007217.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(6316..7542)
                     /locus_tag="ACN3HL_002397"
     CDS             complement(6316..7542)
                     /locus_tag="ACN3HL_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HHC8007218.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(8296..8496)
                     /locus_tag="ACN3HL_002398"
     CDS             complement(8296..8496)
                     /locus_tag="ACN3HL_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HHC8007219.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8630..9238)
                     /locus_tag="ACN3HL_002399"
     CDS             complement(8630..9238)
                     /locus_tag="ACN3HL_002399"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HHC8007220.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(9323..9793)
                     /locus_tag="ACN3HL_002400"
     CDS             complement(9323..9793)
                     /locus_tag="ACN3HL_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HHC8007221.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9841..10755)
                     /locus_tag="ACN3HL_002401"
     CDS             complement(9841..10755)
                     /locus_tag="ACN3HL_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HHC8007222.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10901..11704
                     /locus_tag="ACN3HL_002402"
     CDS             10901..11704
                     /locus_tag="ACN3HL_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HHC8007223.1"
                     /translation="MTTKQLIISSFIRFKDLKESRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11882..12829
                     /locus_tag="ACN3HL_002403"
     CDS             11882..12829
                     /locus_tag="ACN3HL_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HHC8007224.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         3913 a         2544 c         2121 g         4295 t
ORIGIN      
        1 aaaacttgcc atacttttta tttgttttat tttccagtat actatacgaa aggaaggtgg
       61 ctagaccatg aaagttgtac aaacaaaaga tacaatgagc aatatttact tagatgctgt
      121 acggatcagg catcaagttt ttgtagtcga acagggtgtg cctttgtctc gagaaataga
      181 caaagatgaa gcccattgta tccacttcgt cctgtactca gataaaaaag aaccgcaagg
      241 aactgtacgt cttttgcctt tagaaaacgg aaaaatgaaa ttacagcgga tggcgattct
      301 ttctgaatac agacaccaag ggttaggaaa aatattgatt gaagaagcag aaaactttgc
      361 taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg aaacttttta
      421 cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca tgcctcatat
      481 ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca gcaagctttt
      541 gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg acaattgctt
      601 gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc cattattgat
      661 ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt tcgggtaatt
      721 catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct cgccgtcagg
      781 aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt ccagcaaaaa
      841 aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg ctattacatt
      901 gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc atcggcgtcc
      961 atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt cgcttgtttt
     1021 taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt aactttggat
     1081 cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag cagcattttg
     1141 tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa taaaaatgag
     1201 ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta ccagtttcat
     1261 ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact tcgaagtttt
     1321 gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa ggagaacatg
     1381 ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct gccaaacaaa
     1441 gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt catcaaacag
     1501 atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct cttgtgtcac
     1561 ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc tttcttcaaa
     1621 ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt cttttggctt
     1681 tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag ctaaacaaaa
     1741 ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag ctgaacctag
     1801 atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt tccgcatcgc
     1861 ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc aaaacaatct
     1921 gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa atgcgatact
     1981 tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt cttcaggcgt
     2041 ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt ggatgttccg
     2101 ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt ctggagcatt
     2161 tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat cgatcactgt
     2221 gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag gatcacgatt
     2281 atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact gatcttgaaa
     2341 ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc tcttcctttt
     2401 ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag ctttgcttta
     2461 cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt ttatctcctt
     2521 gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga tcagctatcg
     2581 cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg atttttctca
     2641 ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct gtctgatgtg
     2701 cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg atttcaggtt
     2761 tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca cttaagcgca
     2821 tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc aattctttta
     2881 agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt aagtatgttc
     2941 ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg tgaaaaccga
     3001 aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat tcccgtcctt
     3061 ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct ccttcagata
     3121 aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt aacataaaca
     3181 tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc aggtattata
     3241 tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa acaattgtca
     3301 aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt gaaggaatcg
     3361 gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa gaagtactag
     3421 tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa gtcaaaaaaa
     3481 caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt ggctgtcaat
     3541 tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt ttgcaagcat
     3601 tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg atcgggatgg
     3661 atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat aagcagactc
     3721 aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct ataacagact
     3781 gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa ctattgaata
     3841 aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc acaatcatgg
     3901 ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc agtaaaaaat
     3961 tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa gttgtttcaa
     4021 tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa acgatccact
     4081 tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat ctttctcctc
     4141 gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa ggaatcaaag
     4201 cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt gggacgatcg
     4261 gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt cctcaagcaa
     4321 tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga tatgaagtcg
     4381 ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct gatggtatca
     4441 tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta ttgaaatacc
     4501 ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga gatctggtta
     4561 atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt cctcagactg
     4621 cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa gaggttgtga
     4681 aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc ttcatgtttt
     4741 atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt taaaaaaagg
     4801 gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc acgtctatca
     4861 cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc acattatatc
     4921 cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga acagttgctt
     4981 tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga ttaggattcc
     5041 aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct gttaaattcc
     5101 aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta gatgtctgtt
     5161 catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca atgaatgtat
     5221 ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt tgatttaagt
     5281 ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata taaccatgcg
     5341 caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata aacaataacg
     5401 tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta aacgctttat
     5461 tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa ggtgaaaaaa
     5521 gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa catgagaatc
     5581 aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa ctttttaata
     5641 acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg ctgtgagcct
     5701 tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa aagatattcg
     5761 tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt tgcttagcgg
     5821 aaatcccgga aaatattact attctttgca acttccacca tttgcaccac ctagctggat
     5881 atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt atttgttact
     5941 taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga ttcagttcat
     6001 ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca ttgcagcaat
     6061 cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt ggctgcatca
     6121 tcgcctggca atgtggctca tgattcctta ttatttatgg gtactattcg caactctatt
     6181 gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt aatttaacac
     6241 atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac tctttattaa
     6301 ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct ggtcataacc
     6361 ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt gacttggtgt
     6421 atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt ggtactgatc
     6481 atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg atccatcacc
     6541 gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat tctcattttt
     6601 caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt cattttggat
     6661 cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca tttgtccttc
     6721 gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg tcgctacatc
     6781 aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt ttaaaatttt
     6841 tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg tcactacttc
     6901 ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca ttcgagaata
     6961 ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga caccatccaa
     7021 agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca aatcttccat
     7081 gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt gctcaattga
     7141 atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat ctaccgttcc
     7201 ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg attttttttg
     7261 tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg ttcttcctaa
     7321 tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat caatgcttac
     7381 tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt ttactgtttg
     7441 gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca gcaaaacgaa
     7501 tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc tctgtttcac
     7561 attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt ttaatcataa
     7621 gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt ctcaaaattc
     7681 ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca gttcgcaatc
     7741 gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta ttttccaaat
     7801 aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc tttgcctacc
     7861 gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct tttgttaaac
     7921 ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga ctcgaactag
     7981 tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag taaaacgatt
     8041 ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg tttcacaaat
     8101 ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact aacgaagaaa
     8161 atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat ttacttagcc
     8221 aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga agtcgtgtct
     8281 ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc gtgcaccttc
     8341 aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt ctccttgaat
     8401 tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc caaatccttt
     8461 ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc caaaaaagtt
     8521 cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc aagctttcgc
     8581 tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt tattttgctg
     8641 cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct gcaatataat
     8701 ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc aaacctagaa
     8761 ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta atagctaatt
     8821 ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg gctgcttttt
     8881 tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct tcttttattt
     8941 ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat gaatggttag
     9001 catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata gcgtccatat
     9061 cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca attgctgaat
     9121 ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc gtttcttcgt
     9181 caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg taagtcataa
     9241 aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta acaaagagaa
     9301 ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact tcttcttcaa
     9361 aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca aggataacaa
     9421 taatttgagt gatgattttc gccacatact cattgctgtt cataacattg atcaacaata
     9481 ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac ttaccgcatt
     9541 caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt ttgttcgtta
     9601 caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc atacttaaat
     9661 caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc aaaccaccaa
     9721 aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct tttaactgtc
     9781 gatactgctt catgagccaa cctaccttat taaaaattct tatttatcat actctatatt
     9841 tcaataactt tcatctttat ttaaaaaaat taattttttt tgatcctttg cctttgtctc
     9901 tgcttggatc gtcacatgtg taataccata ttttaatttt aataaagaaa ttatacgagg
     9961 atatatcttt tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc cgtcgaaaat
    10021 aattatcttt tcgctatact gccaaatatg gacatgatga acatccttta ccccatcgat
    10081 tgcttcaatt tcttgttcca ttttttcata gtcgatagca ggtgcacttt gtatcaaaat
    10141 agcggcagct tttttgatca ccattatcgc ttctatcaat atatatatcg aaatgatcag
    10201 tgtaataact ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg ctccgataat
    10261 cacacttacc gaagacagtg tatcacttaa caaatgcaaa taactagatt ttatattcaa
    10321 actttcatct gcttcttgtc gtaataataa tactgagaac aaattcgcga gcaatccaat
    10381 aactgctact gttagcatca aatgactatt tatcttttct ggtgaagtga accgcttgaa
    10441 tgcttcaacg gttaaaaaca aggataatat gatcaatatg aatgagttga tgaaagcact
    10501 caatatttct aaacgctggt agccatacgt acgtttttta tttgcttctt ttcgggccat
    10561 tttttgtgcc ccgtaagaaa aaataattgc caatgtatca ctaaggttat ggaaagcatc
    10621 tgaaacaaga gacaaactcc ctgacataat ccctccaata aattctgata aagtgatcac
    10681 cgcattcaaa accactactc caaatagttt ttttgatgat ctctgtggct gtgtaggcac
    10741 tattccttcc tccattttat ttatattgga tagtctttag acaagaataa catttttttg
    10801 atatttcacc aatcattcag ctgtttcctt aaagcacttg tatttcactt gatacttcgc
    10861 tagaattgca agtgatgaca ctactagatg aggagtactt atgacaacaa aacaattaat
    10921 tatcagttcc tttatacgat tcaaagacct aaaggagtcg agaaatgtcc cattttggaa
    10981 agccattgtc tatcttttag ttttgagtat aattatggct ttgccaatct cttttcaagt
    11041 ttttcaagtc ttaaacaaca ttcaattgga tgggcaaaag attgctactc gcattcctga
    11101 ttttacaatc caaaacgggc agcttcaaac cgaagaaaaa gaaggattca tttaccaaac
    11161 aaactccatt atcttcacat ttgatccaga gggaaaacga acagaacagg acatctctac
    11221 tgatttgatg gggaattttg ttagtgtcgg gatgttaaaa aacaaactta tcatagctct
    11281 tcctaataca ggcacgactt ctgctttgtt gaacaataac caattagaac ttccctacac
    11341 caatgaatct ttaaaaaact taacaggtaa gcagctccgt tcttttttaa gtgaagcatc
    11401 tataccactt tggataaaag tcctgacatt tatattttct atttatccta gttttctgaa
    11461 tctgctgatc actttgctat ttaccaacat tgctgctttt ctctatgcac gctttcgact
    11521 aacaaaagct acttttcttg attgtttaaa aacattgatc tattcaattt cattgcctac
    11581 tataattgca acaatcttga tggtctttct tccttctttt gacactagcg ccttcattgc
    11641 ttttgcagga atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa tatcgatcaa
    11701 ttaagaaata aagacaactc gttatttcta cttcaataga cccttttaga ggttgtgaca
    11761 tttttttgtc acagcccctt ttttatttga aaaatatttc tttctcaaaa aacaagcaag
    11821 gcgcttcaaa gttcttcttg tatgcgctac acttagagta aagaaaggcg ggaaattaac
    11881 tatgtcagaa agaatcattt atgcagatcg tccatttcgt gatgaattta tcgaagaaat
    11941 ccatactata gcgcctggtt atatctttaa aacagaatta caaccagagg atctacaaaa
    12001 tgtagagatc agtttgggct ggaactcaga ctaccaagaa aaactattag cctcttctac
    12061 cttgaaatgg gtccaatcta tctcagctgg tgttgatcag ctaccccttg agactttttc
    12121 aaagaaacat attttacttt caaatggtag tggcatccac agtgaatcga ttacggagca
    12181 tgtcttagga atcatccttg ggtattctcg tggtcttttt caagcacaaa aggcacagag
    12241 tgacatgaaa tggttaggtt catcggtcca ttaccaatct atccaaggga aaaaaatact
    12301 aatcattgga actggccata ttggaaaaat gattgcaaaa aaatgcaaag cattagacat
    12361 gaactgctat ggaatcaata catccggtca tccagcagaa ggaatggaaa agactttttc
    12421 tttaaatcaa ctaaaggaag ttcttcctga agtagatttc gtagtcaata tcttacctct
    12481 aacggaggaa acaactgggc tctttgatca gcatatgttt gaacactttg atccaaaatc
    12541 tgtattcatc aatgttggcc gtggtgcttc tgttaagaca caagatctgg tgcaggcttt
    12601 aaataaccag caactttcct ttgcagcatt agacgttttt gaggaagagc ctcttccaca
    12661 agatcatcct ctttggaaaa tggacaatgt actgattact tcccacattg caggtttgac
    12721 acctgatttt caaaagaaat taatggctat ttttttaacc aatctgaaaa gctactttgc
    12781 cacccatgag cttcaaacca atcaagtaaa attgtctgca ggatattaat agctgaaaac
    12841 aatattttca aaagaaaaaa gagaaggtga caa
//
LOCUS       DBGZHO010000073        12021 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.076, whole genome shotgun sequence.
ACCESSION   DBGZHO010000073 DBGZHO010000000
VERSION     DBGZHO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.076"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..260
                     /locus_tag="ACN3HL_002404"
     CDS             <1..260
                     /locus_tag="ACN3HL_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007225.1"
                     /translation="LKRKVTDRNKNLLNVVMICYISFLILGLPQAVFPEMFSGDWGIV
                     SYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="ACN3HL_002405"
                     /pseudo
     CDS             467..667
                     /locus_tag="ACN3HL_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="ACN3HL_002406"
     CDS             complement(1379..1984)
                     /locus_tag="ACN3HL_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007226.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="ACN3HL_002407"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="ACN3HL_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2666..2881
                     /locus_tag="ACN3HL_002408"
                     /pseudo
     CDS             2666..2881
                     /locus_tag="ACN3HL_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3019..3990
                     /locus_tag="ACN3HL_002409"
     CDS             3019..3990
                     /locus_tag="ACN3HL_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8007227.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="ACN3HL_002410"
     CDS             4130..5443
                     /locus_tag="ACN3HL_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HHC8007228.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="ACN3HL_002411"
     CDS             5486..6352
                     /locus_tag="ACN3HL_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8007229.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="ACN3HL_002412"
     CDS             6349..7197
                     /locus_tag="ACN3HL_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HHC8007230.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="ACN3HL_002413"
     CDS             7211..8683
                     /locus_tag="ACN3HL_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HHC8007231.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..9572
                     /gene="scrK"
                     /locus_tag="ACN3HL_002414"
     CDS             8700..9572
                     /gene="scrK"
                     /locus_tag="ACN3HL_002414"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HHC8007232.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9808..11190)
                     /locus_tag="ACN3HL_002415"
                     /pseudo
     CDS             complement(9808..11190)
                     /locus_tag="ACN3HL_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11652..11975
                     /locus_tag="ACN3HL_002416"
     CDS             11652..11975
                     /locus_tag="ACN3HL_002416"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HHC8007233.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
BASE COUNT         3738 a         2046 c         2418 g         3819 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aagtggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
     9001 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
     9061 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
     9121 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
     9181 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
     9241 tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag gttgcagaag
     9301 atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac aatacaacct
     9361 tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa cgccatatgc
     9421 tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt
     9481 taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc ggttgtttgg
     9541 cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg acatttagtg
     9601 ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga gtgcttaact
     9661 ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aagttcttgc tcgaaagtta
     9721 tggaaatttc gatagccgta ggctacttgt attgtgcaat agttttttac aaaaaaaagg
     9781 gggtgcggat attttttttg gaccttttta acaaatatat ctttgcttct tccgatattg
     9841 aagagggctt agccttccta aagataactt aattcgttga ttattatacc aatgaatata
     9901 atcatccaat ttgtttataa actgattgat tgttgtattc ttccagtcac gttgataaaa
     9961 catctcgttt tttaatcgtc caaagaaacc ttcgcacgct gaattatctg gtgaataact
    10021 ctttttagac atagagtgaa gcaagttggc tttgttccaa tagtccaact aacaatagca
    10081 ccatcgtaac aatcgacaag tggtgataag tagattttcc ctgcgagaat tctaaattca
    10141 gtaatatctg ttaaccattt ttcatttggc ttctttgctt taaaattccg atttaataaa
    10201 ttggggtgtg caggagaaat ttccccagca tacgaagaat acttttttcg tctagaaaat
    10261 ttaacaaata gattttcctc agtcatcaat ctacgtacaa ctttttcaga aagcttttta
    10321 cccatatttt ttaaagcttg gtgaattcta cggtaaccat acgcacagaa gttatgattg
    10381 aaaatcgtga taattaattt gacgttcttt gtaatactta tctggtttct caagtgcttg
    10441 tttttgataa aaatagctgc ttttaggaaa ctggagctgt tgaagaagct ctttcaaggt
    10501 gaactgattt cgtaaggcat caatcaatat cgttttttct tgatttgata gacaaagaag
    10561 attgacgcct ttttcttttt ttagcagttc agccgctcct tcgagtaatg ctttttcgag
    10621 ctgtaattgg tgtacttgtt tttgtaagtc ttctacttcc tttaaaagta gctctttttg
    10681 tttttcctga ttttttaaag tcatacacaa tggaaaatcc tttccaagaa ccgtgttttt
    10741 ccattgatat agagtaactc tactaattcc tccagattcg gctaaatttt tcctattagt
    10801 ttgcggttta tagaattttt tcaacacagc ttctttttga tcttgtgtta actttaccgc
    10861 actttttcgg agttttctag ctcctggtgc aagttcttca caccgctgcc gcaaggactc
    10921 tctattagga taaccaagca tgcgaatggt tcgtgcataa cattgaccat attcaaaata
    10981 atgattcacc gctattcgtt tttgttcttc agaatacttt gatttttttc ggtgctcctg
    11041 atggagctct ccggattcca aatactcttt ataccatttc cgtagtgcac caatcgacgg
    11101 ataccctaat tctcgaatgg ttgcagcata agagcaatcg tattttaaaa ataactgaat
    11161 tgcccttaca cgctctttgt gggaaaacac acggacattc ctcctaagtt tattttttcg
    11221 tccaggatta tgtccgcacc cccttgcttt ctgatgactt attctggttc tttgagtgtc
    11281 aatgcataga tgtgatgtag ctagttagaa aaaaattttg aatactcttt ttttctttca
    11341 gactcctttt taagtaagat tttgaagtgt gagttacggg gtcagaaact taaaagtttt
    11401 tgatccttta ttttcaagtc tgatttggca gcttttcggc agctcattta tttatggtca
    11461 gaaatagatg ctgaaatttt aatctattag caaatagtcc agaacgtatg aagaggagtc
    11521 ggatatcatt tgtcattaac accataaata tttataaaat tcgtgttcac ctacaattaa
    11581 atttaatata taatattcgt tgtaagggct tataattttt tgttaatgaa caagatagga
    11641 agaaacattt aatggacagt tttcagagat tgtcactagt aaatcaattt gagttattgg
    11701 ctaaatttga ggaccaaaac agatcttatt atgaaagaaa aatcgaaata ttgagagaag
    11761 gttacgagta tcattatgat gatgaaattt ggagtgatct ttctgagcca tttccgaaag
    11821 aagattctcg atttgtatta gatgtattga acatgtatcg agatatcaat tttagtaaat
    11881 caaagctaaa cttagatgaa aaccaaatta ctaattcata ctatactcat ttcggttctg
    11941 ttgcaaagtt ttccaaaaaa tctattttag tgtaaaattg agaaaaaaga cagagaggac
    12001 agagtaatga atcattttaa a
//
LOCUS       DBGZHO010000074        11255 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.077, whole genome shotgun sequence.
ACCESSION   DBGZHO010000074 DBGZHO010000000
VERSION     DBGZHO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.077"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(18..1247)
                     /gene="hflX"
                     /locus_tag="ACN3HL_002417"
     CDS             complement(18..1247)
                     /gene="hflX"
                     /locus_tag="ACN3HL_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HHC8007234.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1249..2166)
                     /gene="miaA"
                     /locus_tag="ACN3HL_002418"
     CDS             complement(1249..2166)
                     /gene="miaA"
                     /locus_tag="ACN3HL_002418"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HHC8007235.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2170..2907)
                     /locus_tag="ACN3HL_002419"
     CDS             complement(2170..2907)
                     /locus_tag="ACN3HL_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HHC8007236.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2998..3525)
                     /locus_tag="ACN3HL_002420"
     CDS             complement(2998..3525)
                     /locus_tag="ACN3HL_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007237.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3705..4298
                     /gene="clpP"
                     /locus_tag="ACN3HL_002421"
     CDS             3705..4298
                     /gene="clpP"
                     /locus_tag="ACN3HL_002421"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HHC8007238.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4402..4887)
                     /locus_tag="ACN3HL_002422"
     CDS             complement(4402..4887)
                     /locus_tag="ACN3HL_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HHC8007239.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5040..5237)
                     /locus_tag="ACN3HL_002423"
     CDS             complement(5040..5237)
                     /locus_tag="ACN3HL_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007240.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5332..7092)
                     /gene="efrB"
                     /locus_tag="ACN3HL_002424"
     CDS             complement(5332..7092)
                     /gene="efrB"
                     /locus_tag="ACN3HL_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HHC8007241.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISELLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7089..8819)
                     /gene="efrA"
                     /locus_tag="ACN3HL_002425"
     CDS             complement(7089..8819)
                     /gene="efrA"
                     /locus_tag="ACN3HL_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HHC8007242.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9212..9424
                     /locus_tag="ACN3HL_002426"
     CDS             9212..9424
                     /locus_tag="ACN3HL_002426"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HHC8007243.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9426..11105
                     /locus_tag="ACN3HL_002427"
     CDS             9426..11105
                     /locus_tag="ACN3HL_002427"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HHC8007244.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2430 c         1971 g         3589 t
ORIGIN      
        1 gttaaaaaaa taaaatttta ttggtttttt cttaaccatt ttgaattggt ttttgcaaac
       61 cctttaactt catattcgtt tgtttcttcc atgtacgctt cgtccaaaac cattgtttgt
      121 cttctcaact cgcttaattt ctgtccttcg ttgcttggca cagaaagtgt ataaggggtc
      181 attagttcca tcagctgacg tttgattgct tcgatcaacg ccatcttacc ttctttcgtc
      241 tgagtagaaa tcaatacatt tgggaatagc gtaggcgtga acatcgctgg gtcgatctgg
      301 tctgccttat tgtaaacagt cagtatcggc atttctttca tattcagttc atccatcaat
      361 tttaagacag tctgctcctg taaaatacga tctggagaac tagcatcgac tacatgtagc
      421 aaaagatcca tattttgact ttcttctaat gtagaatgga aagcatcgat cagttgcgta
      481 ggcaggtctt ggatgaaccc gacggtatcc gttacagtaa tctcaaatcc ttcagcaaaa
      541 cgccatctct tagtcaatgg atctaacgtt gcaaacaatt gatctttcga ataagtatcc
      601 gcttgtgtca atagattcaa gatagttgac ttcccggcat tcgtgtagcc aataagtcca
      661 atctgaaaaa tctcgctatt ttttcttttt tggcgattgc gctctcgatg agcttctact
      721 tctttcaatt ctttcttaac agcaaaaatt ttattccgta tatgtcggcg gtctgtttct
      781 aactttgttt cacctggccc tcttgttccg atcccaccgc caagacgaga taatgttttc
      841 ccttgcccta ctaaacgagg cagcaggtat tctaactgag caagttcaac ctgcagcttc
      901 ccttctttcg aacgagcacg catcgcaaaa atatctaaga taagctgcac gcgatcaatt
      961 accggaagac caacagcatc ggtaatcagt tggctctgtc tcggagttag ctcatgatta
     1021 aagatgatca aatccgcttc atgcgcatcc gcttgttgaa ctaattcttg taatttccct
     1081 ttaccgataa tcgtttgccg atccacttgt ggtctctttt gtgtaattgt gaatacgact
     1141 tctcctgatg cggtattcgt cagctgaact agctcttcca ttgactctga aaagtaacgc
     1201 tggtttgctt cggtttctac ccctacgatg atcacttttt cttccatttt attccgcctc
     1261 cagccatttt ttgattgttt gctcaatctg acttttttga tttggctcac ttataagatc
     1321 aaaccactgt gcatccaaac ggttacgaaa ccacgtcaac tgacgtttcg cgtatcttct
     1381 cgaatgtagt ttgacttgtt ctgttgcttc ttccaatgtt tctttccctt caaaataagg
     1441 gaaaaattct ttatatccaa taccttgact ggcctggact tctccaagct catacacctt
     1501 acgcgcttct gctactaaac cttctgctag catcaaatcg actctttgat tgattcgttc
     1561 ataaagaata ctacgcttcg tatctaatcc aatcatgagg taatcataca attgctttgg
     1621 ctcttcttta ggtgccgtga tactatgtcc tgtcgtctct aaaacttcca gagctcttat
     1681 cactttgcgt tgattgttcc agtggatttt ctcagcagct gccgggtctt tttctttcaa
     1741 ctgattccat aatgcttggg aaccaattgt ttcagctaac gtttcatact tttttctaat
     1801 ctcaggattc gcttcttctg tcgctcctaa ctgataatca tatagaaggg attggatata
     1861 gagacccgta ccaccagcta tgataggtag gtgccctcgg ttcgcaatct cggtaatcaa
     1921 ttgtcgacct gaatgctgaa aatcagcggc tgagtaacgt tgagtaggtt cgatcacatc
     1981 aatcaaatga tgcggaacat tattcatctc ttcttctttg atttttgctg taccgatatc
     2041 cagattttta tagatttgca atgaatcacc actgatgatc tctcctccaa atagttgtgc
     2101 gagttccaca cttagcgctg ttttaccgac tgctgtcgga ccgacgatca ctaatacttt
     2161 ttccatattt tacctacttt tcgttgattg tttccaccga agagctttct ccggaaaatc
     2221 agttattatt ccatctattt tgagttcttg acatttggcc atttcttctt catcgttaat
     2281 cgtccatgca cgaattgctt ttggaaaatc agctgcctgg actggatgtt cgaacaacca
     2341 agtatttttt ggatgtactc cttctatata aggggtttct gctgctagtt ggatcttttt
     2401 atcagaagta ctcatcaata agtccagctg tatctccggt tccagtaatg cgattttttc
     2461 caaagaatcc aaatgaaagc tgcaatatgc atgttgaaaa ggccaatctc tactttttaa
     2521 tgtttcggct aatttttctt cgataccggg atattcatac tgatcagttt taatttcaat
     2581 cattagcatc cctcggtaat ttttttggag gagcagtcct aacacttctc tcaattcagg
     2641 aactttagct gctggaaatt ctttgctgaa tttgccccct gcattcaatt ttttgagttc
     2701 ttccaatgtt ttttctcgaa tcagcccttt accgttagtc gtccggtcca cttcttcgtc
     2761 gtgcataacg atcaaataac catctttgct tagatggaca tctagttcga taccatctgc
     2821 acctactcgt acagcttctg caaatgcagg aagcgtattt tctgggtggg tgccgctgct
     2881 tccgcgatgg gcatagattt gtaacatctt tcttcactcc gttcagttct attgtatcat
     2941 taagaaaaaa agaaagcatt accacgctct catgtgcaac ggcaatgctt caaaatatca
     3001 gctccaaaca tcatctttcg agaagaaacc aatcggctgg cgcgtcatag tcttcaactg
     3061 agcttttttt tcattgatca tttcagtcag actatccgta aaattctcta aaatcacgcg
     3121 tccgccttta taagcatatc caccaatctt cattgtttca tctggagata aaatcacttt
     3181 tcgatgggag atattcttaa atagctcgtc taaaatataa tttggcagat aaaaactatt
     3241 ttgcgctgaa aatgattgga gatacgcaaa atcgtcaatc gtgatataac aatcatcaaa
     3301 tgcatcaaag ctgacatatt cttccatcag cgttgtccgt ttttgcaaga tctcgttgat
     3361 ctttttattt aattgattca gcgtctcgat ttctttgact ttcaattcca attcacgtct
     3421 acgctgttct ttattttcca agtgacgcat ttgcagtatc atgccgatat agacaactac
     3481 agcacctgtc agcactccga taaggccagt aataccaact atcaatctgt tgttcctcct
     3541 tgttttgttt ctctgcttat cataccataa agcgggttta tgcgactaat ttgcctaagt
     3601 tttttatttg accttttttg accaaaaatg tatactacat tttaggtatt agaaactaaa
     3661 ttatggtaca ctatttctaa acgaaatcaa ggaggaactc tattatgaat ttaattccta
     3721 cagtcattga acaatcttca cgaggtgaaa gagcttacga tatctactca cgtttattga
     3781 aagaccgtat catcatgtta agcggccaag taacagatga tcttgctaat tcgatcatcg
     3841 cccaattgct tttcttagac gctcaagatt ctgaaaaaga tatctatctt tatatcaatt
     3901 ctcctggtgg ttcagttaca gcaggtatgg ctatttacga cacaatgaac tttgtcaaag
     3961 cagatgtcca aacaattgtt atgggtatgg ctgcttcaat gggaagcttc ttgctgacag
     4021 ctggtacaaa aggtaaacga tttgctttac caaatgctga gatcatgatc catcaacctc
     4081 ttggcggcgc tcaagggcaa gcaactgaaa tcgaaattgc ggcacgccat attttgcaaa
     4141 cacgcgaacg cttaaacaaa attttagctg aacgcactgg acaaccgctt gaagtgattg
     4201 aaaaagatac agatcgtgac aactatatga cagctgaaca agcaaaagca tatggattga
     4261 tcgatgaagt catggaaaac agttcttcat taaattaatc tgtttcaaag gaagcttttt
     4321 taagctctct tatctaaacc aaataaaaaa ggatggtcaa ctcaaactga ccatcctttt
     4381 ttattttatg gatgctactg cctatctttg ctccttgaat tttccttgcg catgcatccg
     4441 acctatctcg acataatgct ggatgttttc tttgtttttt tgtatttctt cttttgtcaa
     4501 aggacggatc actttagctg ggcgaccaaa agccaagaca ttaggaggaa taacttttcc
     4561 ttctgttact aatgatccag caccaatcaa actattctca ccaataaccg catgattcaa
     4621 tatcgtggtc cccatcccga tcagcgcccc tttttcgatt gtacagccat gtagcatgca
     4681 ctgatgtcct accgtcacat tctccgcaat atctacaggt gcatcatgat cgacatggat
     4741 gattgtacca tcttggatat tcgttctttg tcctattttt atccaattac tgtccccgcg
     4801 taaaacagct tgataccaga tcgtcacatc ttctgacaat gtcacatcac caatcactgt
     4861 ggcatttgat gctataaacc gttccatatt tatttttctc ctttcatttt ttgtagaaac
     4921 taatcctatt gaataaaggt atcatagcat atatttattt cataagaaaa aaaacaggta
     4981 aaacctgctc aggccagatg tctatttaca gtatctggta actgacgttt tacctgtttt
     5041 tattgtacat ctatattttc ttctattact ttttttaaaa ttaattcgta cacttctatt
     5101 tgtgctgcca agcgttcgat ttgaaactca ttttcaaaaa aatcagctga atcaaaaggc
     5161 ttcgtctgac agacgtgcgt taaacgatca acttctcttt tggcttcagt aattttttca
     5221 tttaaaaact gttccatctc cgtgtcctca cttttcttga taactttact ttaccattat
     5281 caagaataga gaacaaaaaa taagttttaa actgttttat tcttatatga cttattctgc
     5341 ttcctcagca aattggctgt tatacagttt ttcataaaat ccaccttgtg ccaataaact
     5401 ctcatgcgtt cctttttcaa tgatctgacc ttgatccatc actagaatca gatctgcatc
     5461 acggattgtc gataaacggt gagcgatgac gaaacttgtc cgtccctcca tcacgcgatc
     5521 cattgctttt tgaatcaacg cttctaaacg ggtgtctact gaacttgttg cttcatctaa
     5581 aatcaagatt ttaggatcgg agaccactgc tcgggcaatc gtcagcaact gtttttgtcc
     5641 taaagacaca ttgtctccct cagaattgat ggccatatca tatccatctg gcatcgttcg
     5701 gataaaatga tctacgtttg ctgttttcgc agcatcaact acttcataat ctgtcgcatc
     5761 aagctttccg aagcggatat tatctgcaat cgttccttga taaagccatg catcttgcaa
     5821 gaccatacca aatagcgaac gcacatcact gcgactcatt gatttggtgt cgattccatc
     5881 aatccttatt gctcctttgt ctacgtcata aaaacgcatc aatagattga tcaatgtcgt
     5941 cttgccggca ccggtcggac cgaccacagc tacggtttga ccagctttca cttcaaaatt
     6001 caaatcttgg attaatggtt tcttcggatc atatgcaaaa tcgacatgat cgaatgtcac
     6061 atctcctaaa atcgtttctg gcagtgaagc atctactttg ttttcttttt cttctggctc
     6121 atctaaaatc tcgaatacac gtttcgttgc cgctgatgca ctttgcaaaa ctgaagacaa
     6181 ttgtgtcacg ttccccattg gctgactgat ttgccaaata tattggatga atgcttgtag
     6241 ttgaccgaca acgatcgccc cagtaataac ataaaagctt cctagaacag ccataccaat
     6301 ataagtagca taggcagtta attgaactag aggcatcatc aagccagaaa tgaatgctgc
     6361 acgaaaccca aagtatttca agctgtgatt aacttttttg aatccttcca atgtttcttt
     6421 ttcgcgtcca tatactttca atacactaaa acctgtcata ttttcttgga cgtagccgtt
     6481 tagctcacca agagaattct gcatgctttg aaaatatttc tgcgaagcat tgatcactcg
     6541 ttttgagatc cagatcgatg ttggaatcat gatcatagag atcagcgcca tcatcggctg
     6601 gatataaaac atcattgctg cagccaacgt aattcccaat atcgcattta cgataccaat
     6661 aaaagcttgt tgtaaagcac cgctgactgc atctacatca ttcgtcacac gagacaaaat
     6721 atttccttgc tggtttttat cgaaatatga aaccggaaga cgattgattt tttcttctat
     6781 gtctcttctc aaatcatgca tggcactttg aacgacattt gtcatcaaaa caccagaaag
     6841 taattccgaa atacaatacc ctattccaac aactgtgatc caaatgagac atttgaatat
     6901 ataagaaaaa ttgattgatt cgccattggc aatattacgg ctgatttctg tagtaggaag
     6961 tcctgtaaca tatggcaaag ccacgttgaa agccactgtc agaactgtaa ataggatcac
     7021 taaaagaaaa gtctcacgat acggtctgat atatcgagct aaacgtttta aggaagaaaa
     7081 ggtttttttc atgctaattc ctcctttgat aattgagaag cggcaatatc ataataaatc
     7141 gggcattttt ccaacaactc ccgatgcgtc cccataccga cgacttctcc ttcatttaat
     7201 acgatgatct tatctgcatg catgatcgtt cccacacgtt gtgctacgat caatacagta
     7261 gattctgtcg tttctttttt cagacgagca cgtaacttcg catccgtttg ataatctaat
     7321 gcagaaaagc tgtcatcaaa aatatagatt tccggacggc gtatgatggc tctggctatt
     7381 gccaatcgtt gtttttgtcc acctgaaaaa ttggaaccac cttctgataa atgttcatta
     7441 aatccatctg gttttcgaga aatgaattct gaagcttgag caatctcagc tgcacgttcc
     7501 atttcttctt gcgtagcatc ttctttcccg tatcgcaaat tatctgcaat cgttccagta
     7561 aatagcagcg ctttttgcgg aataaaccca atcttatctc gcaacttgct tagccgataa
     7621 tctctcacgt ctactccatc gatcaagatc tttccttcac tcacatcata aaagcgaggg
     7681 atcaattgga tcaacgtaga ttttccgcta ccggtacttc caataaaagc aacggtctct
     7741 cctggagagg ctgtaaaact gacatttcgt atcactggct cttgcgaatg gcctggataa
     7801 gcaaatgtta cattttgaaa ttcgatatac cctttagttt ttgtatcaga tataccattt
     7861 ggatcttcta caatcgaagg tttggcatct agggcttctt ggatacgtcc agctgaaaca
     7921 gctgctcttg gatacatcat gaacacacta gcaaataaca tgaatgagaa caaggcatgg
     7981 aatatatact cgataaacgc aatcaaatct cctacacgaa gctcgcctgc atcgatttgc
     8041 actgccccgc tccagatgat caataccatt acgatattaa ataagaaata aaaacccggt
     8101 tgtgcaacag ccatcaaacg gaataagctt tttgaactag aagcataatt ctcattgact
     8161 acagcaaaac gtttttcttc aaacttttca ttgacgaatg cacgaatcac acgcaatcct
     8221 gaaagatttt cccgcaagat actgttgatt ttatctaagt ttttttgttg ctttttagat
     8281 aacggttcag acaccttagc aatcgctacg actgccaata atagtaaagg taatgcacct
     8341 actacataca aactgagtgt cacacttgta cgcatgacca tgtacaaact gacaatgaac
     8401 atcattggtg ccataaaacc gatacgtaaa atattttgca ggaacaacat gatctgataa
     8461 gcatcgtttg ttgtacgagt gatcaatgaa gatacgccta gattttcgta ttcctgatgc
     8521 gaataacttt ggatcttttc gaacaaatca tctcgaatat ctgctacgat attagtcgta
     8581 atcctcgaac caaaataacc taacaagata ttcaaaataa taccgattac agtaataacg
     8641 atcataaata tcccttgttg cttcacataa tcaaaatcat cattgcggat tcctacatcg
     8701 atcatacgtg ctaaaatcgt aggaagtcct aattcaatca aaataaaacc aaatacgcat
     8761 atgaaattga aaaacaagaa tttcttataa cgcatggtat aatgccacat tagtttcact
     8821 ttctcatctc cttttaatct tttgttacat tttcattact aaaaatgata gcacaacgag
     8881 cctattaata gaacacttct ctcataaaaa agtcattatg attatagcgg gatgataaac
     8941 attgattttt tctttcaatc tagttgattt ctatacttat ttgctgtttt atgctagaat
     9001 aacaattaat tgttgtatat tttttataca gaaggtacgg ttgaaaaaat atccgaacag
     9061 ataagcaaaa acgaggcttg tctctttgac tcgaatccag tattctagtc aaagcatatg
     9121 aaaaaccagg tggcttgtcc cctcgttttg tgttgtctaa aaaaatcaac tagctaaatc
     9181 actgctttac gcagataaag gagacaaaac aatgatctat aaagtttatt atcaagaaac
     9241 aaaagtacgc aaccctaaac gggaagaaac aaaatctctt tacattgagg caaaaagcga
     9301 tgtagacgct cgccaacgtg tggaagaaaa taccccatac aatattgaat tcgttcaact
     9361 tctagaagga agtcatctag agtacgaaaa agaaaatgct gatttctcat tagtggagtt
     9421 ttaatatgaa actttccatc aaaaataacg agacaggcgt ctttgctatt ggtggattag
     9481 gtgaaatcgg gaaaaatacg tatggggtac aattccaaga tgaaatcatt ttgattgatg
     9541 ccgggatcaa attcccggaa gacgatttac ttggaattga ctatgtcatt cccgactaca
     9601 gctacatcat acaaaactta cacaaagtaa aagccttggt gattactcac gggcacgaag
     9661 accacatcgg cggaataccc tacttgctga aacaagcaaa tattcctatc tatgctggtc
     9721 ctctcgcatt agcgttgatc acaaacaaat tagatgagca tggcttgctt cgagatgcag
     9781 agctccatga gatcaatgaa gatacgatca tccgttttag aaagacttct gtcagctttt
     9841 tcagaacgac ccatagtatc ccagatgcat tagggatcgt ggtgaaaaca ccttctggaa
     9901 atatcgtagc gactggagac ttcaaattcg atttcactcc tgttggcgaa ccagcaaact
     9961 tgcataaaat ggctcgtatc ggggaagaag gagtcttgtg ccttttatct gatagtacaa
    10021 atgctgagat tccaacattt actaaatcag aaaaaacgat tgggcattct attttgaaga
    10081 tcttttcaaa aatcgaagga cgtatcattt ttgccagctt tgcttctaac atcttccgtt
    10141 tgcagcaagc agcagatgcc gctgtggcaa ctggtcgtaa aatcgctgtt ttcggacgaa
    10201 gcatggaaaa tgccatcgtc aacggtcaac gtttaggata tatcaaagtt ccagacggca
    10261 catttgtaga tgcacacgaa atcaatcgct tgcctgccaa tgaaacgatg atcctatgta
    10321 caggttctca aggagaagcg atggccgcgt tgagccgcat cgcgaatggt actcaccgtc
    10381 aaatccaaat ccagccagac gatacagtga tcttttcaag ttcacctatt cctggtaata
    10441 caacaagtgt caatcatttg atcaatttgc tgtctgaagc tggtgcagaa gtgattcacg
    10501 gaaaaatcaa taacatccat acttccggtc acggtggaca agaagaacaa aaattaatgc
    10561 ttcgtttgat gaagccaaaa tattttattc ctgtccacgg agaattccgc atgttgaaag
    10621 tacatgcttc tctagcacaa gatgtaggtg ttcctgcaga aaactgcttc atcatggaaa
    10681 atggcgatgt tttagcgtta actagcgatt ctgcgcgtcc tgctgggcat tttgtggctg
    10741 gagatgtgta tatcgatggt agcgggatcg gtgatattgg taatgtcgtt ttacgtgacc
    10801 gtcacctgct ttcagaagaa ggtcttgtat tagctgtcgc gacagtggat atcaagaaaa
    10861 aagaaatctt ggctggtcca gatattctct ctcgtggatt tgtctacatg cgagaatcag
    10921 gagaaatgat caatgaagct cagcgaatct tattccacgc tttaagagaa tgtttgaatg
    10981 gacctgactg ttcagaatat aaattgaaag aagcgatgac tggcgcgctt cagcctttct
    11041 tattcgaacg tacagaaaga catccaatga ttttgccaat ggtaatgaca ccagatgaag
    11101 aataaataag aggttatgaa atcagcacct tgtcctgaat ataagagaaa acaaatgaaa
    11161 aacatgagaa gccatttttg tttgttctta ttccttgata caaggtggct ctttcatagc
    11221 ctcttaaatt tatttacttt ttcatacaaa aaaat
//
LOCUS       DBGZHO010000075        11188 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.078, whole genome shotgun sequence.
ACCESSION   DBGZHO010000075 DBGZHO010000000
VERSION     DBGZHO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.078"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(102..709)
                     /locus_tag="ACN3HL_002428"
                     /pseudo
     CDS             complement(102..709)
                     /locus_tag="ACN3HL_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            1232..1906
                     /locus_tag="ACN3HL_002429"
                     /pseudo
     CDS             1232..1906
                     /locus_tag="ACN3HL_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            1899..2060
                     /locus_tag="ACN3HL_002430"
     CDS             1899..2060
                     /locus_tag="ACN3HL_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007245.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            2544..3140
                     /locus_tag="ACN3HL_002431"
     CDS             2544..3140
                     /locus_tag="ACN3HL_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HHC8007246.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            3121..3567
                     /locus_tag="ACN3HL_002432"
     CDS             3121..3567
                     /locus_tag="ACN3HL_002432"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HHC8007247.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            3910..4233
                     /gene="relB"
                     /locus_tag="ACN3HL_002433"
     CDS             3910..4233
                     /gene="relB"
                     /locus_tag="ACN3HL_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HHC8007248.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            4553..4780
                     /locus_tag="ACN3HL_002434"
     CDS             4553..4780
                     /locus_tag="ACN3HL_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HHC8007249.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            4796..5962
                     /gene="hemW"
                     /locus_tag="ACN3HL_002435"
     CDS             4796..5962
                     /gene="hemW"
                     /locus_tag="ACN3HL_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HHC8007250.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6197..7240
                     /gene="hrcA"
                     /locus_tag="ACN3HL_002436"
     CDS             6197..7240
                     /gene="hrcA"
                     /locus_tag="ACN3HL_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HHC8007251.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7334..7897
                     /gene="grpE"
                     /locus_tag="ACN3HL_002437"
     CDS             7334..7897
                     /gene="grpE"
                     /locus_tag="ACN3HL_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HHC8007252.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            7948..9777
                     /gene="dnaK"
                     /locus_tag="ACN3HL_002438"
     CDS             7948..9777
                     /gene="dnaK"
                     /locus_tag="ACN3HL_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HHC8007253.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            9928..11094
                     /gene="dnaJ"
                     /locus_tag="ACN3HL_002439"
     CDS             9928..11094
                     /gene="dnaJ"
                     /locus_tag="ACN3HL_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HHC8007254.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
BASE COUNT         3943 a         1788 c         2284 g         3173 t
ORIGIN      
        1 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
       61 ccatcagtaa aattacttgt catactattg ataaggagta tttaattgaa gagaatgatt
      121 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
      181 tctttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
      241 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
      301 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
      361 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
      421 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
      481 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
      541 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
      601 tagaagcagt tttgttttgc catccctctt tttggtttag tgtgctagta atataagcac
      661 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
      721 cctttactat ctatgacaag gacaacagtt ttaacataca gacattcatt aaatttggat
      781 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagaca gtcaacttaa
      841 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
      901 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tcttaaaaga
      961 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
     1021 tgaaaacaac cctagaaata tataactagt ccaatgaaaa aaaagcgaat gccgtagaaa
     1081 acaaggattc tgcgtacatt catatctcat tttgcgagca tatctgctat tactgtgact
     1141 aaatgttaat atggttaaaa tgaccgttat attttttata taaatatcgt ataattagta
     1201 tgaatataga agaaggaaag aaggtgcaat cttggaacct aaagacaagt atttagatta
     1261 cgctagggtc aataaagata aatttattga aacaatcatc aagggaaaaa tccctgatga
     1321 tgaaaaagat gcggtattca tggctggaag cccaggagca ggtaaaacag aggttgcact
     1381 aggtttagct taaaattatg acaaccatgt tgtgattgat gcggactatt ttagagcaca
     1441 atttccagaa tacaatggaa agaactcaag tgtttttcag aaagcttctt cttggttagt
     1501 tgaacaatca ttaaaatatg tactggaaca tggctattct ttcatactag aggatacttt
     1561 tgctatcctt agtgcagaga aaaatattat tcgagccctt aaaaataact ttcgcgttac
     1621 gattttctat gtttaccaag atcccaaagt tgcctgggat ttcactcgaa aacgtgaact
     1681 agctgaagga cgtcatgtgc caaaagaaat gtttatcaat gcgtttttta agtccagaga
     1741 gaatattgaa aaagtcaaaa atagacatcc tgaagtagtc cttcacataa tgattaagga
     1801 ttatcaaaac gacatttctg aagtgcatta tgcagcagat aatattcaat tagtactacc
     1861 aatacaatat acttcaaaag agttggagga ggaattacat gactgagaaa gaacaagtac
     1921 aacaaatcgt gaagaagtat aataaaagta tcgctgattt atcagaaaac gcctcagcga
     1981 aagaatttaa aacagtaatg aattacgtag cagatgaagc aaatcgtaag cagcgaaaac
     2041 tagttgggtt ggataaataa attttttaaa ccatatcctt gtaaagttga gttttttatt
     2101 ttaatgaatt aagactatta aatagataat tattgtaact taaaaaacac agctaaaaat
     2161 tagttgtgtt ttttattagg tttacttttc tggtataaaa ggaactagct actttttcaa
     2221 aatttctaaa tcattcaata tgtagcgctt actaaattat tcgccataaa attttataat
     2281 tggatcactc attgttttac ctaagtcata tttaagtaat aaccggtgtt tttacataag
     2341 aagacttcgg gtatttttta gtttgattag ctctgatata cctataaaga atatgctaag
     2401 gtaagaatag taaaaattca catagatgag gtataataat gatattttta tatattacag
     2461 ataacttgac acaaaatgag tttttttcga tttttcaagt tatctaatgc aattatattg
     2521 atatcattag gagctgcatt gttatgaatc caacattgat tactaagaaa gaattactaa
     2581 aaaaattaga tatttctact ggtgtattag ctaatttaat tagaaatggc atgccaaaag
     2641 agggagaaat gtttaatctt gataagatta ttacatggcg agaaaattgg tctaaaaaca
     2701 tattaggtga gttagaagtt ggtagagtat atactaacaa agaaatttca gagaagttta
     2761 aatgttccaa acagggtgga atgagaagat ctcatcaaac taatactctt gtactgttta
     2821 gtgatcaaac aggaagtaat gtttataaag ataagtggtt aaatggtatt ttacaatata
     2881 ccggtatggg gctaaaaggg gatcaagtat tggataagaa tcaaaataaa gttttagcca
     2941 attcaaaaag taattttgta aagattcatt tatttgaaac atttaaacca aaagaacaca
     3001 catatctggg agaagtatat ttagcaggac aaatatatac tgttaatgaa aaagatagtt
     3061 cgggcaacag cagaaaagta tataaatttc cattagcttt aataaatcaa gagcaattga
     3121 ttgaagataa agatatataa ccaggaagaa aatcaaacta gacatattcg taatttatct
     3181 aatgctaaat tagaggaaga agcaagaaaa gttagtaatt ataataaaaa aatggctgca
     3241 aaatatgtta acgaagagga gttttgcttc tcaaaaacaa aaatatataa acgtaatccc
     3301 ttcgtatctg aatatgttaa acgacttgca aaaggtattt gtcaactttg ccaagaaaaa
     3361 gggccattta taaaagacgg tgtaccttat ttacattgtc atcatataga atatttgtcg
     3421 caaggtggaa aagatgtgat tgaaaactgt atcgcgttat gtcccaattg tcatgctaga
     3481 attcatgaac ttgagttacc tgacgataaa gaaaaattgc tgaagatcgt tgaaaaaaga
     3541 gaaaatagct tttctaaaat accgtaattt atttttatag gacaaataag ctaatgtgag
     3601 ctatgccttc tatataagac taagttctat tataagtaac gaagtaattc tcgttccttc
     3661 ctgtagtaat attttttaaa taacctatag gcttcttcaa aagtacatcc tccagtaaat
     3721 tctaagtact ggaggattct ttttctagtg ttgctttact catgaaaaag tagttggcta
     3781 cttcatcaaa atttctgaac ttttttaatg tataataaag agctcgatca tttactacaa
     3841 ggatgctagc tcctacattt tcacagtttt ttagcaagta aatttttcta aaatcacatc
     3901 aggaaatgca tgagattctt taagagaggc aattataggg ctatgattac ggttcgtgta
     3961 agtgacgcca aaaaagaatg gctttcttat atggctgaat tttatgggat tactttatct
     4021 gaacttctaa aaaactattc gatggaacaa ctagaagatg aatacaatcg tcaaacggct
     4081 gaaattgccc ataaacattg gataagaagt gggaaaacaa cagtattcat ggaagaatcc
     4141 ttaatgaatt tggtgggctg gaatgacctg ccgtttaaaa ttcacgcccg aaattcagaa
     4201 gcagctctga ttggcaaata cgtgtattgg tagagataga agataatcaa ttcgttgtta
     4261 tcgctattca agtagggcac cgaagaaatg tctatgatta agagactgtt tatttttaca
     4321 aaaaaataat aattggaatc tagttaaaac tcttgaagtg agagatttga ctagattttt
     4381 ttatgaataa aataaggaca aaattgttta ggaagaatca tgagtgtaaa aaaatcatcc
     4441 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
     4501 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
     4561 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
     4621 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
     4681 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
     4741 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
     4801 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
     4861 gcatatctgc tattactgtg actttaataa agttttttta gaagggcagc cagtagatga
     4921 gtatgtggaa atgctgctga atgaaatgag attaatgctg gaaagtcatc ctacagcgaa
     4981 tttggaaaca ctttatgtag gaggcggaac accaacttct ttatctgcta aacaacttga
     5041 tcgactatta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
     5101 agaagcgaat cctggtgatt tgacccgtga aaaacttcaa gtgatgaaaa actatggcgt
     5161 caatcgttta tccatgggag tgcagacatt tgacaatcgc ttattgaaaa aaattggacg
     5221 taaacatact gcagaagatg tgtatcaaac aatgcaattt ttagaagcag aaaattttac
     5281 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatcggga
     5341 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
     5401 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
     5461 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
     5521 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
     5581 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
     5641 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
     5701 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
     5761 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
     5821 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
     5881 tgaagaagac cgtgtttatt tgacaccaag agggactttt ttggggaaca atgtgtttga
     5941 gcgcttttta tttgaaaaat agtttgaaga atatttgttt tttatcgaaa cttgaaaaga
     6001 aaaagtttag aaagtttgac aatgaggtat tgaagtattg atataactgg atttacatca
     6061 attatttaga attagcactc ttgtgtttag agtgctaaaa aatggagtct ttctcttgac
     6121 aggagaaggg cttcttgcta tatttataag tgaattagca cttagaatat atgagtgcta
     6181 atgagaggtg aggaagatgt taacaaagcg acaaaacgac attttacgtc tgatcatcca
     6241 acactatacg agtagtggcg tgcccgttgg ttccaaaaca ttaatgtctg agggagtcaa
     6301 ggccagctca gcaacgattc gcaatgatat gaaagcatta gaagatgaag gattgctgtt
     6361 gaagactcac tcttcttctg ggcggattcc atctgcttta ggctatcgtt attacgtgga
     6421 tcatttgtta aaacctgctc gcgtagcaga agatgatttg ctgctgattc gtcagtctct
     6481 aggcagagaa tttcatgaaa tcaatgagat tattaagcaa tctgctgaga tattatctga
     6541 gctgacaagc tatacgactt tttcattggg acctgaaata aaagaccgcc gactgactgg
     6601 ctttcgtatc gtacccttga ataatcgaca gattattgct atcgtcgtaa cagatatggg
     6661 gaatgtagaa agccaagtgt tcactcttcc cgaatatatg ggaagtcagg aactagaaaa
     6721 aatggtacag attgtaaacg accgtctagt cggagatcct ctgatgacgg tgtaccataa
     6781 acttcgtacg gagattccga tgattcttca taaatatttc cagacgacag aagggatgtc
     6841 tcagttattt gacaccgttc ttggtcatgt ttttgaagaa aaggtttatg tcagtggaca
     6901 aatgaatctc ttggattatg agccccgtca agatcttgat cagttcaaat cgatgttttc
     6961 ttttatgaaa gactcagacg gacttacaca aatgatcact ccgatggata gcaatattca
     7021 tatcaagatt ggtgctgaat taggcaatga tttattgcag aatatgagta tgattcaagc
     7081 aagttacgag atagatggtc atggaagagg tacaatagcc ttgttagggc ctactagtat
     7141 gccttattct cggatgttcg gtctagtcga tgtttatcga agagaactag cagctaaact
     7201 tgctgattac taccgctcgc ttgacttgtc aaactcgtaa tgtgaataac gaagctattt
     7261 gcagctgatc gttctctctt tcttagtaag agcaatcaaa cagctgactg aataatgaaa
     7321 ggaagactgt atcgtgaaag aaaatcaaga agaactagat aaagaaatga cagatgctca
     7381 gccagaaccg gaaatcgatg tcgaagctgc agaagattcg ggtatttcag aagctgaagc
     7441 ggaagaattc gaaacagcga aattaaaagc tgagttagaa gaaatggaag ataaatactt
     7501 gcgggctcgt gctgaaatcg caaatatggc aaatcgagga aaaaatgagc gtgagcaatt
     7561 acaaaaatac cgttcacaag atttagccaa aaaattactt ccatcaattg acaacctgga
     7621 acgtgcatta gccacagaag tgtcagatga tcaaggggca ggtttgaaaa aaggcgtgga
     7681 aatggtcttg gaaagtttgc gtaacgcact ggaagaagaa ggaattgaaa aaatccctgc
     7741 taaaggagaa gcctttgatc ctaatcttca tcaagcagta caaactgttc cagcgactga
     7801 agatacacca gccgatacga ttgtagaagt actacaagaa ggctacaaat tacatgatcg
     7861 cgtgttaaga ccaactatgg tcattgttgc acaataattg tgcggatata aaacttacac
     7921 tttcaattaa agaaggagac gttaattatg agtaaaatta tcggtattga cttaggtacg
     7981 actaactctg cagtagcagt attggaagga aacgaagcaa aaatcatcgc taacccagaa
     8041 ggaaaccgta caacaccttc tgttgtatca ttcaaaaatg gagaaatcca agtaggggaa
     8101 gttgcaaaac gtcaagctgt gacaaaccca aatacgattt catcaatcaa acgccatatc
     8161 ggtgaagcag gttacaaagt agatgtagaa ggtaaatcat atacaccaca agaaatctca
     8221 gcaatgatcc ttcaatatat caaaggattc gcagaagact atttaggtga aaaagtcgaa
     8281 aaagcagtta tcactgtgcc agcttacttt aatgatgcac aacgtcaagc aacaaaagat
     8341 gctggtaaga tcgctggtct agaagtagaa cgtatcgtca atgaaccaac tgcagctgct
     8401 cttgcctatg gtttagataa aacagatcgc gacgaaaaaa tcttagtatt cgaccttggt
     8461 ggcggtactt ttgacgtatc tatccttgaa ctaggagacg gtgtctttga tgtattgtca
     8521 acagctggcg acaaccatct aggtggggac gactttgata acaaaatcat cgactacatg
     8581 gtagcagaat tcaaaaaaga aaacagcatt gacttgtctc aagacaaaat ggctttacaa
     8641 cgcttgaaag acgctgctga aaaagcgaaa aaagatttat ctggcgtatc aagcacacaa
     8701 atcagcttgc catttatcac agcaggagaa tctggaccat tgcatttgga aatgacattg
     8761 acacgtgcaa aatttgatga attaacagct gacttagtag aacgtacaaa agtaccagta
     8821 cgtcaagcgt taaaagatgc aggtctgtca caatcagaaa tcgacgaagt tattttagtc
     8881 ggtggatcta ctcgtatccc tgcagttgta gaagcagtac gtaaagaaac aggaaaagaa
     8941 ccaaacaaat cagttaaccc tgatgaagta gttgctatgg gtgctgctat ccaaggtggc
     9001 gtgatcactg gtgatgtgaa agatgttgtt ttacttgacg ttacaccatt gtcattaggt
     9061 atcgaaacaa tgggtggagt gttcactaaa ttgattgacc gcaatacaac gattccaaca
     9121 agtaaatcac aagtattctc aactgcggca gataatcaac cagcagtaga catccatgta
     9181 ttacaaggtg aacgcccaat ggctgctgac aacaaaactc taggaagatt ccaattgaca
     9241 gatattccag cagctcctcg tggtattcca caaatcgaag taacattcga tattgataaa
     9301 aacgggattg taaatgtatc tgcgaaagat ctaggtacac aaaaagaaca aaaaatcacg
     9361 atcaaatctt cttcaggtct aacagacgaa gaaatcgaac gtatggtgaa agatgcagaa
     9421 gcaaacgctg aagcagataa agctcgtaaa gaggaagttg acctacgtaa tgatgtagac
     9481 gcattgctat tctctgtgga caaaacattg aaagaattag aaggcaaagt ggacgaagaa
     9541 gaagtgaaaa aagcagaaac agctcgtgac gaattaaaag ccgctgttga agcaaacaac
     9601 atcgaggaaa tgaaaactaa acgcgatgca ttgaacgaaa tcgttcaaaa cttgactgtt
     9661 aaactatacg aacaagctgc acaacaacaa gctcaagaaa atccagaagc agctcaaggc
     9721 ggagcagatg atgtcgttga tgctgatttt gaagaagtcg atggcgacga taaataatca
     9781 gttcactgaa tttcgagaga aggccaaagt tgctactttg gctttttctt ttgaaaaata
     9841 gtttgaagta tcggtttttg tttcaaacaa aatatgatat gataacaagc gacgtgaaaa
     9901 tgatgagaac caataggagg aaagcctatg gcaacaaaac gtgattatta tgaagtctta
     9961 gggctctcaa aaggagcatc agaagatgaa ataaagaaag cttatcgtaa gctttcgaaa
    10021 aaataccatc ctgacatcaa taaagaacct gatgcggaag aaaaattcaa agaagtatca
    10081 gaagcatatg agattttaag tgacccgcaa aaacgcgctg catacgacca atacgggcat
    10141 gcaggcacag atccaaatta cggtgctggt ggagctggtg gcggatttgg tggattcggc
    10201 ggcttctctg gtggcggctt cggtggtttt gaagatatct tcgactcttt ctttggagga
    10261 ggcggtcggt cagtcgatcc aaatgcgcct cgtcaaggtg ctgatttgca atatacggtc
    10321 gacttgtctt ttgaagaagc gatttttggt gtagaaaaag aaatcaagta taatcgggaa
    10381 gaaatctgtc atacttgtgg tggaaacggt gcaaaaccag gcacacaacc aactacttgt
    10441 cataaatgtc atggtgcagg tacgatcaat gtagaacgcc aaacgccact tggacgagtg
    10501 atgagccgtc aaacttgtga tgtttgtcat ggcacaggga aagaaatcaa agaaccttgt
    10561 ccaacctgtc atggctcagg acatgagaag aaagcacatt cagttaaagt gaatgtacca
    10621 gctggtgtag aagaaggaca acaaatgcgt ttagctggtc aaggagaagc tggagaaaac
    10681 ggcggaccat ttggtgattt gtatgtggtt tttcgtgtag aagaaagtga tatctttgat
    10741 cgtgaaggtt ctgaaattta ctatgaattg cctttaagtt ttgtacaagc agctttgggg
    10801 gatgaagtcc aagtaccaac tgtccatgga gatgtgaaat tgaagatccc tgctggaaca
    10861 cagacaggta cgaacttccg tttacgtgga aaaggcgctc cgaagttacg tggtggtgca
    10921 acaggcgacc aacatgtcaa agtaaaactg atcacaccga aaaatctaaa tgaacaacaa
    10981 agagaagcat tacgtgcatt cgctgaagct ggcggcatca aagttgaaga acagcaagaa
    11041 gacggtttct tcgataagtt taaagatgct tttggcggga aaaagcggaa gtagtttttc
    11101 tagtaaaaat ataaagtaga cttgcccaaa ttttctattt ctagtaaaaa cgctaagtca
    11161 ttaataatta aaaaccagac gaacaatc
//
LOCUS       DBGZHO010000076        11150 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.079, whole genome shotgun sequence.
ACCESSION   DBGZHO010000076 DBGZHO010000000
VERSION     DBGZHO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.079"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="ACN3HL_002440"
     CDS             6..305
                     /locus_tag="ACN3HL_002440"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8007255.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACN3HL_002441"
     CDS             378..1739
                     /locus_tag="ACN3HL_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HHC8007256.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACN3HL_002442"
     CDS             1761..2021
                     /locus_tag="ACN3HL_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007257.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACN3HL_002443"
     CDS             2035..2787
                     /locus_tag="ACN3HL_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HHC8007258.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACN3HL_002444"
     CDS             complement(2881..3486)
                     /locus_tag="ACN3HL_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8007259.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACN3HL_002445"
     CDS             complement(3542..4516)
                     /locus_tag="ACN3HL_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HHC8007260.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACN3HL_002446"
     CDS             complement(4894..5613)
                     /locus_tag="ACN3HL_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007261.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACN3HL_002447"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACN3HL_002447"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HHC8007262.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACN3HL_002448"
     CDS             7164..8561
                     /locus_tag="ACN3HL_002448"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8007263.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACN3HL_002449"
     CDS             8642..9082
                     /locus_tag="ACN3HL_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HHC8007264.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACN3HL_002450"
     CDS             9229..9555
                     /locus_tag="ACN3HL_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHC8007265.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACN3HL_002451"
     CDS             9556..10305
                     /locus_tag="ACN3HL_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HHC8007266.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACN3HL_002452"
     CDS             complement(10331..10741)
                     /locus_tag="ACN3HL_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HHC8007267.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3538 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa
//
LOCUS       DBGZHO010000077        11042 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.080, whole genome shotgun sequence.
ACCESSION   DBGZHO010000077 DBGZHO010000000
VERSION     DBGZHO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.080"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(112..381)
                     /locus_tag="ACN3HL_002453"
     CDS             complement(112..381)
                     /locus_tag="ACN3HL_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HHC8007268.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(371..604)
                     /gene="relB"
                     /locus_tag="ACN3HL_002454"
     CDS             complement(371..604)
                     /gene="relB"
                     /locus_tag="ACN3HL_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HHC8007269.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            complement(706..930)
                     /locus_tag="ACN3HL_002455"
     CDS             complement(706..930)
                     /locus_tag="ACN3HL_002455"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HHC8007270.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            complement(1138..1770)
                     /locus_tag="ACN3HL_002456"
     CDS             complement(1138..1770)
                     /locus_tag="ACN3HL_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8007271.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            complement(1783..4506)
                     /locus_tag="ACN3HL_002457"
     CDS             complement(1783..4506)
                     /locus_tag="ACN3HL_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8007272.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            complement(4643..5608)
                     /locus_tag="ACN3HL_002458"
     CDS             complement(4643..5608)
                     /locus_tag="ACN3HL_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8007273.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            complement(5662..6474)
                     /locus_tag="ACN3HL_002459"
     CDS             complement(5662..6474)
                     /locus_tag="ACN3HL_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8007274.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            complement(6488..7261)
                     /locus_tag="ACN3HL_002460"
     CDS             complement(6488..7261)
                     /locus_tag="ACN3HL_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHC8007275.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            complement(7275..7745)
                     /locus_tag="ACN3HL_002461"
     CDS             complement(7275..7745)
                     /locus_tag="ACN3HL_002461"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8007276.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            complement(7742..8158)
                     /locus_tag="ACN3HL_002462"
     CDS             complement(7742..8158)
                     /locus_tag="ACN3HL_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8007277.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            8501..9325
                     /locus_tag="ACN3HL_002463"
     CDS             8501..9325
                     /locus_tag="ACN3HL_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HHC8007278.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            9729..10337
                     /locus_tag="ACN3HL_002464"
     CDS             9729..10337
                     /locus_tag="ACN3HL_002464"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007279.1"
                     /translation="MTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLLPQP
                     KARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTVCVF
                     IQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPFSNA
                     GFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            10452..10730
                     /locus_tag="ACN3HL_002465"
     CDS             10452..10730
                     /locus_tag="ACN3HL_002465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007280.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(10784..>11042)
                     /locus_tag="ACN3HL_002466"
     CDS             complement(10784..>11042)
                     /locus_tag="ACN3HL_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HHC8007281.1"
                     /translation="GITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFFSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         3458 a         2155 c         1762 g         3667 t
ORIGIN      
        1 taaaaaagca gaaaccaacc gatagtatcg ggtagtttct acctgtggta ttatgcaaaa
       61 ttcaaaagat tatacattga ctttcgaaac tctacttcgt tccaaaaacg gttatctttt
      121 atatattgta cttctatgtc caattgagaa tatctggatt tcaatttcag aatcacaaat
      181 attagccaat attcgatagt ttccaattcg atagcgccat tccccactct tatttccagt
      241 caaacctttt ccgtgctgac gcgggtcagt cgtgttttct aaattctttc tgatccaggc
      301 gacaattatt ttagcttggt ttctgtccat tttttttaat tgcttctggg cttgcggcat
      361 gtagatgact ttataattca tttagcagtt tctccatttc ctcttgagaa ataccactct
      421 cttttttctc tttggaaact tcaattgcac tccgtaaagt ccgtagatcg atttcatctt
      481 cgattttatc cagtacagca tttcgataaa gttcggtcaa tgaagaattg tgtgcttttg
      541 catattctaa taccagttct ttttcatcgt cgggaatcct aaatgtaatg gttgattgag
      601 acatgattct acctccgttc atcatttgta ctaacattgt actaaataaa atcctttttg
      661 tcaatacaac gttagtacaa acaagatttg catcatatcc attattcaaa ttctttgaga
      721 tagcacggta tcgcaaaatc tctgactgat cgttttaaga agctggtcat tttgaagcga
      781 ttttctccaa ttttcaggga tcacttcacc cccgtaaaga atacccgcaa gagcaccagt
      841 tacggcagca gtagtatcag tatcccctcc taaattgacc gcagtcaata tggctgcttg
      901 ataactattc gtattttggt tctgttgcaa aatattctag caatccctag gatcattcac
      961 atgaccttag ggattgcgaa caaaataaaa aacttaaaaa gccaatccca ttatcactgc
     1021 cgaagcattt tcgtaaaagg tgttaccagc accttttact acacctgaat tatagcaagt
     1081 ttttttggtt agtcaaaata gctagcacag atatatagcc ttatttccat taattcacta
     1141 acctttttct aaaacaattt gttccagttc ttgtagactt tcaatttgta tgtctgcttc
     1201 actctgatcg atttgcattg gttgttttag tgccgccgta tagatatttg ctgcctttgc
     1261 tgatttaata ccaatcgttg aatcctctac tgcaataaag aagtcacagt ctaattgctg
     1321 tttcgctttt aaatatattt cgggatgtgg tttgctttgt tttaatgact caccacttat
     1381 aacaaaggaa aaatattcag taagttcaca ttgaatgagc atactctcta tctcgacagc
     1441 tggagaagaa gatgccagtg ccaatggtat atcccgcttc ttgaggaagt caagtaacgg
     1501 tttcacttct tttcgtaaag ctttagcgaa atcaattgga tgcgtttttc gataatctac
     1561 atatttcgga taaagttcct ctcttaatga tttgtcctca ggaactaatg tttcccatat
     1621 tgcagcttct gttttcccca cataatcatc aatctggttt gatcctggat ctatctccag
     1681 ttcttgaaag aagttcattc ttctctcaaa ataaaatgtc tcgctatcta tgagtacccc
     1741 atccatatca aaaattactc ccattgtcat tcgaattcac tcctatcctt gaacaatatc
     1801 gctcaataat cgcaactcta aatctggtat ttcaattgtg tattcccttt caatctcaaa
     1861 aaaagcgcta tgaattttat ccattatttc tccatttgct tgcatatatt cttcaatgtc
     1921 ctcttgctca tccacacttt ctttacgtac aattcgttca atcatacaac tacagtgaag
     1981 gtacaacaaa aacagctgat tattagaaaa atcaaaattt aataacttcg ataattcttt
     2041 aattgctttt tgtacaaaag atagcacctt atctggatcc aaaatggtta aattttcgac
     2101 aattttacta attgaaaaat tgaaaattaa ttctttttgt aaatcgttca cttcaatagt
     2161 cagctctttt tccaagtaat gaacaaattc gccaatgctt cccccattaa tcaggcgatc
     2221 taatccaata tatggaatct gattaatttt gggatcttct gtacctacaa tcatgatgac
     2281 atcgtataat tgaaaaggag tctcaaaatt cttgttttct aacagctttt tgtaatcata
     2341 cggaataatt actaattctc taactgcatc tttcaagcat ttcgttaaaa tctcctgaat
     2401 ctgggtcgca ctaccaatcc ctgtataaca acaagtaatg atggctttct ttttcttttt
     2461 cttgggaagt agtaactgct ttttgaaagt aagacttgtt tcaatttctg ctcctatttc
     2521 ggtgatactt ttattgttta atacttgttg gccgacttcc aataataacg gtgtattgat
     2581 atgatcaatg attaacagtg gtccatttag atgattcact aataaaccgc ctagttggtt
     2641 tagtgaaccc atatctacca ataaaatcaa gcctgaatct gttcgataat ctccaaggaa
     2701 ttgaatcaat tttgcttcaa ttttctctaa tgtaatatct aaaggcatat cataagcttg
     2761 aaaaacgttc ttattcagca tacggttggc aacattcgcc atactactag ctgtagaata
     2821 accatgagct agcacaatac tcttaatacc tgttttaaca ttcgtgacat tcaaactata
     2881 aaaatatagc gtaataaaga aaatgtcctc ttcatacaca ggttgatcta aacactcaga
     2941 taaaaggctt aagatttttt ttgcatacca ataaggggtt tcaagaacat tagcaaaaaa
     3001 ttcgttaagc tgatctttgg ttttcttttc ttgaagacta ttttcaaaaa tcacttgatt
     3061 atccttgaca tatagatagt tggccaaagc gactacccgg ttaccatctt gttcaaaccc
     3121 gtagctttct cgcataaaat caatactttg acgaatatga tagtttagaa tggcgtataa
     3181 agactgctct ttttcgtaat cctcttgaaa aataagcgta tccattactt gtgttacctt
     3241 ggtaaccatt tcttctaaaa atagtttaat atccttgtta ttttcaatca cttcagagaa
     3301 tccagtaagt aattggtcaa aaaattgaac aaaaagctga ttgtttcttt ctagttgcac
     3361 ttgtcgtgtt tcttctggat agtagattcg atctgctctt ttctttctgg gtttatttag
     3421 ttgctccttg aatttataac tgtactctaa aggcatatcc aataatttaa cttgaattgt
     3481 ttgctgactc ttctggtgga tatatgcgtt tccgcaagca tacttgataa tatttttaat
     3541 attccccacg ttaccttcaa aatcactatt cattaagaaa tgaatcaatg catcagaaac
     3601 agatagttcc ttagctaaaa tttggctctc agaaacaaaa aattcatcaa tcaatgacag
     3661 acgttcaaac gacggacgtt gttgaaatct aggtagatta acaataactg gcaatctcct
     3721 aagaaaagtt ggtaagaaag tcgtatatat attttctgtt gttgcaaaga ctaatcgaac
     3781 atcggctttt ttccgaatac tattatcccc cataggagag aattcacccg tatccataaa
     3841 tgtaaataat ttctcttgcc cttcttcaga taagcgatgc acttcatcta aaaacaatac
     3901 tcctccatcg gctttttcta gcaaaccagt atgctcctgg cttgctccgg taaatgctcc
     3961 tttcgtgtag ccaaataaag cagaggatag taactctgga ttgctcacat attgtgcaca
     4021 attataatct atgaaaggtg ccgatgtgtg aatgaccttt tcttctactg catattcata
     4081 tattttattc gctagaaagg ttttccctga tccactagcg ccgatcaata ataaaggcaa
     4141 cccttttcca ggatataaga ctgccgtttt aatttgatca attgcttctt tcaaacttcc
     4201 tttagagcca attacttgat ctaatgcggg tttttgagaa attgttaaca agctttcaat
     4261 tgattctatt tcggagttat tcagtgtgat atgtagttct tcaagagctg ttctatgtaa
     4321 aaataaaacc gggtaacttt ttacttttat gaaaagccct tcacgaacac cttcatttaa
     4381 gtagctactg attgtacttc tattcaactg tagagcttgc gaaatactgc gagctgaata
     4441 attatctgaa ggcgtagatt tcaaaagcaa tgttagttga taaagatagt catttaatcg
     4501 ctgcatcttg ccacctgctt tcacaatatg tactagttat tttaccatat gtactagtta
     4561 ttttaccata tgtataaaat cacattgaag aaaacaaggt ggcttaattt ctcaagccac
     4621 cttatttagt ttgatctatt ttttaataag ttagtttcca catataacgt ctcttagtta
     4681 atggatgttc tcttgcttct gacaattctt ctgcataaac tctaaatact gcagtaatca
     4741 cgaatgggtt aaagtagtct aagacttctt tagcaatatg tgaagacaag ccataatcca
     4801 aggcatctac aacttctgtt ttcgtatcaa agcgttcaag gaaagttaat gctcgagcat
     4861 ctatatttct agtttttcca tcattcatta ataatataaa cggtacgtct ttatccacaa
     4921 tttcgaatgg tccgtggaaa aattctcctg aatggaaggt accagaatta atccattgca
     4981 tttccatcat caagcaaatt gatgttgagt atgctacttc atgtgtagca ccactactca
     5041 ttacataaat aactttttca tctttaaagc gttcagcaaa tttcttcgca tctttacgag
     5101 ctgattctgc acttttttgg gcaagatcat agatagtagc aaatccttct tgcattgctt
     5161 cataatggtc ataaccttct acttgatgta aaagttctac tgccaattct aaacagtagc
     5221 ctgttttttc taatttagca gcatagttct ctgcaaatcg atgataaatt acataatctg
     5281 catcttttgt taacggtgag tcaatgcttc gtgttagact aataactgta gcaccttttt
     5341 ctttagctac tgcgttagct tcaactgttt ctggagtcgt acctcctaaa gaagctgaaa
     5401 taacgacagt tgactcatct acagatgctg gtgttgcata gttaaattcg ctggctgtgt
     5461 aatgactaat ccgtaactgc ttcgcatttt ggtctagaaa atactttgca ggataaaggt
     5521 ccgcttttga agcgccacag ccaacaaata cgattgattt tacctctttt ttcgctacga
     5581 tttctttaac aatttctttt gaattcatca attgaattcc tccttattta tattattcaa
     5641 ccaaatttat tggttattcc cttattgtaa gatacctaac aaactaaaaa taattcctcc
     5701 gactaaacag attgccaaca tccatcctgt tttgaccttt ttctgcaata accagtacat
     5761 gaagaaggtt aatcctaatg gtaaaaattg tggcataata ctatctaata catcttgtaa
     5821 gacaaaagct ttacccattt gaattggtgt tgtaatcccg atcatgctgg caatcatcga
     5881 accaatgacc atcaacccca caatggagca aacatacatt actttatcca tcaaaccttc
     5941 ttgatacagt ttagacaagt atttattccc catgttatag ccaattttcc caccatagta
     6001 agtaactaaa aaggaaggta caaaggaaat taacattgct agaattggac ctaaaatact
     6061 accttgttgg gctaaattaa ttcctagtcc aaaggctaat acccgaatcg ttccttgaaa
     6121 gaaagaatca ccaacaccag atagcggtcc catcagagaa gtcttcactg cactgattga
     6181 ttccggatta aagttttctt ggtcttcgta gtattgctcc tccatagaag cagttaaccc
     6241 taacacaaat gcacttgttt gaggggtaca gttgtagtac atcatatgcc gctcgtaagc
     6301 ttctttcttc attgcttcat cttctggatt cttgtaaatg ttatctagaa ttggtgcaat
     6361 tccgtacata aaacccatgt tcatttgtcg ttcatagttc catgaggctt gaattgccca
     6421 tgaacgccat aagaactgcc gatatttcca tgcattttga tctttctctt tcacttaatc
     6481 tacctcctta taagtcatct aatggatctg gctcattttg gttaccattt gagtttttac
     6541 cttgaacttg aaccatgaca aacgcaacaa tacatgcgaa ggctgcaata ccaatgattc
     6601 ccaatccaga ataagcagta attaaaaatc caagtaataa aaatggcacc atttttttcg
     6661 ttaacatcgt ttgtaataac aacgcaaacc catatgctgg taaaatttta cttgcaaccg
     6721 ttaagccatt tgttagccac tcaggaatcg catcaacaat ctgagaaaca agattcgttc
     6781 caaaataaat tgctagaaaa ataggaataa aatacatgag agcatataat cccgagccat
     6841 aaagtatatg aattctcctt gcttggctaa attttccttg ttcgataaag cgatccgcaa
     6901 cgtgagtcaa atttgacaaa atcgtccgca ttaagatacc tagtatttga cctaacactg
     6961 aaattggaat ggcaatcgtt aatgctgctt ctgcattcgc atttgataaa atggcaaagg
     7021 ctgtagcaat aattgatgcc atattcatat caggtggtga agcagctccg atatttacta
     7081 atcctaagga catcaattcc aaagaggctc caacaattaa tcctttttcc atgtctccaa
     7141 gtaccaaacc aacaagcgta ctgacaatca acggtcgttc aaaattcatt cttcctaaaa
     7201 gccttgagtc taaaatacaa aaaacaccga ttaaccctaa accaattgac tgaacgagca
     7261 ttttcattcc tcctttataa cattgtattc aaatcttctt ttttagaagt tggtacctgt
     7321 tgaataaatt gtttaatgcc aagagctttt aattttttgg catcttcttg ctcagattca
     7381 ttcaagaaaa tggcattact aaattgcttg gaaccttctt ttttgattat ccctccatag
     7441 ttgatttctt gtactttagg ataggcttca caaaattgac gaatttcttt tgtattacca
     7501 aaaataagca tgatattttc gttaagtgtt tcgattttag gcattttttc tagtaactgt
     7561 tcaactgaaa aaattgttaa tttaatgcca gtcggtttag ataaattcaa agacattttt
     7621 ttgaattcat cattcgctgc ctctttattg gcaataataa tacgattgat atttaatgat
     7681 ttactccaag aaaatactac ctgtccgtgc aacaaacgat ggtcaatacg tactaactta
     7741 atcataggtc atctcctcca gtaagttgtt ctactaataa ttttctacaa tcaatcactg
     7801 attgttgact ctctttaata agcttttcta gctcactttc cccaattttt ccattatagg
     7861 ttgcaataga aataactaaa ggtaagttca ttccagtaat taattgcaat ccctcatact
     7921 ctttaataat agtgagcata tcattattca cactaccacc tagaatatca gttaaaatgt
     7981 aggtttcttc tatatctatt gtggctaaaa gtttttttat ttgtaccaaa atagattcat
     8041 cttcatctct aaatgctgac aaggcatgaa ttggtacact atctccaata atcattgtcg
     8101 ctgtttgctt taatccttga gcaaattccc catggctggc aagaattata gttgccattt
     8161 tcattcctcc tatccttacg cttttctata agcaagatgc gtgccaattt taggaaacgc
     8221 tgttaattaa aggtttttct atatcatgcc aacacttttc tttccctaaa ttatagtgtt
     8281 gatgaaagtg tgggtattta aaggtgtcta attaaatgat cactgtaatt ggaatttagc
     8341 tttgccccaa tcccccgcca catcctaaga aattttcttc cacatacgaa ataaagcgta
     8401 aaaagcgtcc attaatattt ttttcggtaa ttacaacaaa aaatagaact taatgtgcta
     8461 caatatatga atacacgttc atgtgaaagg agatgttata gtggaaatca aggttttatt
     8521 tgaaaactca agaataaatt tgaactttaa aagtggacat gggttatctc tcttaattaa
     8581 ctactcaggg aagaaatatc tcttcgatgc tggcgctaat aaaaaattag tctataatgc
     8641 gactaaaatg ggggaaactt tgaatgatct ggaggcagtg attatttcac acggtcattc
     8701 tgaccacacc ggcgggttaa gatatttaaa atcaggaaac gcccctattt atacagctga
     8761 aggtgtaact ttaccccatt atttaaagat tttaaccacg tttctgtatg ttggtattcc
     8821 taaaaatgaa atccttaaaa tgcatgagaa tttacataca ataaaaacga aaacagaact
     8881 tgctccgagc ttccatatca tccccctagg caaagcaaac tcgaccacca agaatttata
     8941 caaaaagatg gatgataaat ttgtttatga tgatttttca gatgaattat tggtcgtaat
     9001 tgagcaagaa gacggtctga ttgtctttac tggctgtagt catcatggca ttatcgatat
     9061 gatggaaatt gctcttgaaa catttccgac taaacccata aaatacctaa ttggtggctt
     9121 ccatatgatt ggcatacctt atataaataa tttaggtcta cctgagcaag aggtaatgaa
     9181 aattggaaat aaattgaatg actcacgagt agaaaaaatc cttacttgcc actgcacagg
     9241 ttcaaaagcc ttcaacatat taaaaacaca gttaggaaac aagctagaag ctattaaaac
     9301 tggacagcac ttagagataa gttaaaagag aaactgatag gactgtcgag aggacaaaag
     9361 ctatatgaaa taccccctct aatgtttgct ggcgataaca caaaaggcag accttctgtg
     9421 aatagggcta cctttttgtg ttttttcact aactttcaat atcttggtca ttcaaggaaa
     9481 atcacctata tttctgtgtg ggtttacttc cttattaaat cgagtcatct atttcgttta
     9541 ttcacttttt caagtggaca ttcattaagc tgtttatggc agaataaaag tacatacaag
     9601 tgcaacgaaa aactacacaa ctccgcaaat cgattaagtt aagataaaaa gccattgcgg
     9661 gcaacctgaa actcctctaa agttatagtc tcgacactgt aactggaggt aagaaaggta
     9721 tgctcacaat gaccgatatt aatactatca gaaatttacg aaataatcat gataaatcca
     9781 ttaatcatat tgcaaaggag ctagatgtaa attggcgcac ggctaaaaaa tatgcagatg
     9841 atgatttgct gccgcaacct aaagcacgca aaaagactgg tatgatgtat acagaaaagt
     9901 ggggaggcat cgtttcccta tggctttcag aagatgctaa gctgccaaat aaaaagcgta
     9961 ggactgctga agcaatgact actgctttaa aagccgatgg ctttccagga tcctaccgaa
    10021 cagtctgtgt attcattcaa gattggaaag cgacacacta cttggaaaca ctggaagacc
    10081 aaggctttga gcgtcttgaa cacccgccag cagaagcgca acttgatttt ggtacgatgg
    10141 aagtttgtca cgatggagcg tttaaagatg tgaaggtatt agtgatgact ttccctttta
    10201 gtaatgcagg attcgccgtt gtactccccg ccgagaatca agaatgtttg ttggaaggca
    10261 tgaaagaact cttcagccaa tcaggtggcg ttcctcggaa aatacggatt gataatatgt
    10321 caacggccgt tacttagaca aaaacaaaga ctgaacaagc ggtgctgact gacggtttcc
    10381 tccgattttc tatgcactat ggttttgaga cacaggtgtg caatccacgt agcggaaacg
    10441 agaaaggtag tatggaaaac aaagtcggct atgtacggta caacttcttt tcatctacac
    10501 cgattatgaa ggatttcgcc agtttcaacg aggcattagc ggtggagctg tcacacgatc
    10561 gagagcgaat ccattacgaa aaacatgtca ttatcaatga tctatggaac acagaaaaaa
    10621 cagatttgct agctttgccg gacaccgatt acccagtatt taaagaaatc gaagtcaaag
    10681 ccaataagta caacgaaatt aaacaaaaca aaataacaaa tttatcgtag ttcaatatac
    10741 ttgatagaaa aactatttat tttacccgtg gtgctagtta attttaatat cctaaagaat
    10801 atctcaaagt tccttcaaaa cgtcgttgtg ctcgacttaa tagaacactg taagccagta
    10861 atatgctttc aaatctactc tctagccctt taacagaacg tgagttgaaa ttttgacaac
    10921 ctaatttttc taaggaaaaa aaaacagtct caactgtttt tctttgtttt ccaagtaagc
    10981 tgtggtctag tttttctgat ttatccatgt ttttacgtgg cggaacggat atagtaatgc
    11041 cc
//
LOCUS       DBGZHO010000078        10788 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.081, whole genome shotgun sequence.
ACCESSION   DBGZHO010000078 DBGZHO010000000
VERSION     DBGZHO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.081"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..456
                     /locus_tag="ACN3HL_002467"
     CDS             <1..456
                     /locus_tag="ACN3HL_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007282.1"
                     /translation="AERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEH
                     KNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGKS
                     YGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            517..1977
                     /locus_tag="ACN3HL_002468"
     CDS             517..1977
                     /locus_tag="ACN3HL_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HHC8007283.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            1988..4097
                     /locus_tag="ACN3HL_002469"
                     /pseudo
     CDS             1988..4097
                     /locus_tag="ACN3HL_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
     gene            4113..4262
                     /locus_tag="ACN3HL_002470"
     CDS             4113..4262
                     /locus_tag="ACN3HL_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007284.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4343..4939
                     /locus_tag="ACN3HL_002471"
     CDS             4343..4939
                     /locus_tag="ACN3HL_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HHC8007285.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            4952..5851
                     /locus_tag="ACN3HL_002472"
     CDS             4952..5851
                     /locus_tag="ACN3HL_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HHC8007286.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            5854..6339
                     /gene="ssb"
                     /locus_tag="ACN3HL_002473"
                     /pseudo
     CDS             5854..6339
                     /gene="ssb"
                     /locus_tag="ACN3HL_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            6361..6618
                     /locus_tag="ACN3HL_002474"
     CDS             6361..6618
                     /locus_tag="ACN3HL_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007287.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(6777..6899)
                     /locus_tag="ACN3HL_002475"
     CDS             complement(6777..6899)
                     /locus_tag="ACN3HL_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HHC8007288.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7054..7313
                     /locus_tag="ACN3HL_002476"
                     /pseudo
     CDS             7054..7313
                     /locus_tag="ACN3HL_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7761..7967
                     /locus_tag="ACN3HL_002477"
     CDS             7761..7967
                     /locus_tag="ACN3HL_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HHC8007289.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7967..8218
                     /locus_tag="ACN3HL_002478"
     CDS             7967..8218
                     /locus_tag="ACN3HL_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007290.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            8234..8671
                     /locus_tag="ACN3HL_002479"
     CDS             8234..8671
                     /locus_tag="ACN3HL_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007291.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            8664..9359
                     /locus_tag="ACN3HL_002480"
     CDS             8664..9359
                     /locus_tag="ACN3HL_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007292.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            9524..9724
                     /locus_tag="ACN3HL_002481"
     CDS             9524..9724
                     /locus_tag="ACN3HL_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007293.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            9740..9919
                     /locus_tag="ACN3HL_002482"
                     /pseudo
     CDS             9740..9919
                     /locus_tag="ACN3HL_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9981..10165
                     /locus_tag="ACN3HL_002483"
                     /pseudo
     CDS             9981..10165
                     /locus_tag="ACN3HL_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            10199..10630
                     /locus_tag="ACN3HL_002484"
     CDS             10199..10630
                     /locus_tag="ACN3HL_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HHC8007294.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT         3901 a         1828 c         2255 g         2804 t
ORIGIN      
        1 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
       61 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
      121 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
      181 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
      241 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
      301 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
      361 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
      421 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
      481 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
      541 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
      601 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
      661 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
      721 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccactgat
      781 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
      841 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
      901 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
      961 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     1021 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     1081 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     1141 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     1201 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     1261 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     1321 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     1381 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     1441 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     1501 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     1561 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     1621 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     1681 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     1741 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     1801 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttata
     1861 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg agatccagca acaagaaatc
     1921 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     1981 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     2041 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     2101 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     2161 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     2221 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     2281 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     2341 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     2401 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     2461 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     2521 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     2581 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     2641 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     2701 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     2761 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     2821 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     2881 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     2941 gaaatatcta agctatccac gaacagacac cccttatatt acggaagggg agtatgcgta
     3001 tttgttggat catttagatg aatacaagca ttttttaaag gccgaatcaa tcccaacccc
     3061 tattcatacg ccgaatagtc ggtatgtgaa taacaagaaa gtccaggaac attacgcgat
     3121 cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc cactgcagca
     3181 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     3241 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa tcgaaaaggt
     3301 gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa aagagaagga
     3361 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg atctacaagt
     3421 tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcaat
     3481 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     3541 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     3601 tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc tttgccaagc
     3661 cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg aaagctactt
     3721 gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata tccaaaaatt
     3781 tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt ttggatcgac
     3841 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     3901 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     3961 agcctgtgat tttaaaaggt cagaagggtt catttgaagc aacgattgtt ttaaaagaag
     4021 acttcactac aggctttgaa ttttctgaaa agaaaaaaac gaacttcaag aaaagaacac
     4081 gccgcactgc aaaataatgg agggttaatc ttatgcgtaa taccacacac aaacaacaag
     4141 aaatcgaaaa tcaaaaagcc aaaattcgtt cagaacagga aaaaatgcgt gccagcaaac
     4201 gaagactgca gcaattgaag aaccagcaga ggattcaaaa agaaatcgaa ttagatcgat
     4261 aaaatcttcc taactattgt atacgtataa acttatgtta tactgttttt ataagtttat
     4321 acgtatacaa aggagggaga aaatgacaaa agcaatggta tacaagctgc tagaagaatt
     4381 taatggaact ttggctttga aggatgccaa aaaagcgggc atttctcctg taacgatcaa
     4441 acgtatggta gatcgagggg agctggatcg agagtatcca ggttttttca ccttacctgg
     4501 tcaatttcct gatgaattgt ttatggcgca aaaaaaatat gaacgcggca ttatttcaca
     4561 tattaccgcg ttagatttgt atgatttaac agatatgatc cctagacaga tcgatctgac
     4621 tgtaccttac ggttatcacg tttctgaaaa aggattgaag gaattcgcag ttgagctaca
     4681 ctatacaaaa gcggaatggt atgaattagg taagattgaa ataaaaagtc gctatgggaa
     4741 tcctattata gcttatgatc cagaaagaac tttatgtgac atttggaatc cctggtatac
     4801 cgttgaggat gaaatcaaag taaaagcaat caaaaactat atggagtcgg acagaaaaaa
     4861 tcttagaaaa ttgaatgagt atcgacgaat tttaccaaca gacaaaacga tgcgttctta
     4921 tattatggct ttaaattaaa ggagaagata catgacacct acgcagttaa aagcaaaagt
     4981 gaagaatatt tctagagaaa aagaagttga tccgcagctt gttttaagac attttatgat
     5041 ggaaaaattc ttggaaaaaa tctcagagtc tccttatcgt gaaaattttg tgttaaaagg
     5101 cggcttcttg attggctcaa agtatggcat tgaaaatcgc acaaccaaag atattgatac
     5161 gactttacgg gaaatgaaag taaccaaaga aacattaaca acggttctaa acgaaatttt
     5221 ttcaacgccg acgaaagaag gcattcaatt tgagattcaa ggaatgaaag aaacgagaga
     5281 agccgattac tatccaggat ttagcttacg tgtgctggca catttggaaa acatgcggcc
     5341 agattttaag gtagatgtga ctacaggtga ctcgatctat cctgcaacga tcactcacag
     5401 tcataaattg atgtttgagg atcgaacgat tcctttggaa tcctatccta cagaacaaat
     5461 tattgctgaa aaattaagtg caacctttga ttttttaaca gataattcga gaggaaaaga
     5521 tttttatgat ctctatacta ttcctaaaat ggagaagatc gatgagaaga ccttgaaaga
     5581 tagtgtgaga aatacattta cacgtcgagg aaaaactgat ccgttaaaga tatactatga
     5641 aaaggatatg gatgtactga aaaatagtca cgagctaaaa gatacctgga agaaatatca
     5701 aaaaagcaat ccttatgctg cgtcgatcac gtacgatgag acaatggatt cgattagtaa
     5761 tttgatggaa aaagtgattc acgtcgaaga aaaagagcga aaactagctt atcaaagaca
     5821 ccaacagatg aatagagaaa tggagagata aagatgatta ataatgtgac attagtagga
     5881 cgcttaacca aagatcctga tttacgttat accgcaagtg gtactgcagt agcgactttt
     5941 accctagccg tcaaccgaaa tttcacgaat caaaacggca attgagaagc cgattttatt
     6001 aactgcgtga tttggcgcaa accagcagaa acaatggcga cattagctaa aaaaggtagc
     6061 ttgattggtg tagttgggcg gattcaaacg cggacttacg acaaccagca aggacaacgt
     6121 gtatatgtga ctgaagttgt agcagataac tttcaactat tagaaagtaa agcagcgaca
     6181 gagagccgtg cgcacgctga tcaatcgtcc accagtccaa gcaccgccac ctttgaacaa
     6241 cggaatacag cgacgcctaa caacaatgga ttgaacgctt cacagaatcc atttggtgga
     6301 caatcaatcg atattagcga tgatgatcta ccgttttagt ttgagaaaga aggagtaagc
     6361 atggcaaaaa aaattagtct gacgatggat ctattgatac ccgtaattgc atttatagac
     6421 gggatttctt tgggcgtcac tgaaaatcct ttggtaaata gaattgcgaa aggatcacta
     6481 tttcttgtat tcgtgtatct tgtctgttct tatcttttaa aaagagcagg aaaggataat
     6541 tccttttggc gattgactaa agtcacagta gcagcgacag ctgttatact tacggctatt
     6601 ctaccgcttt atatgtagag ttaacgggaa atcgttgaac ttcttgcgaa atattgctat
     6661 aatgaacatg aaaaagagga gttgcgctaa caacccctca ttaacagcac cgattaaaga
     6721 acggtggcag aatattagtt atttggaaat aaccgctgac ctgctaaagt agacggttat
     6781 ttctttttgt catttttaag catatttaca atcaaactaa tcaaagcaat ggtaaacata
     6841 ccaaaaccaa gaatggtttg aattgtctca tatgcggaca aaaggcttac tcctttcata
     6901 gattttagca cttacattca taagcaccac cacctttcca gaagtcgcca ccgtcttcaa
     6961 actttactgt cttgactatt atagcatatc taaaatcgaa taaaaattct caattttagc
     7021 tgtttttgct ataattttag cgaggtgatc gtgatggaac aatatattgg tttactcgat
     7081 aaattagggt gatcaagaca cagccattgc ttgtgcgatt tacattacgc acgagtcatg
     7141 aaccaatcaa ttgtgtagtg gccaatatag aaatagcgga taaattgctg attttggaag
     7201 aaggcaagta tactatttca gtgacaggtc acttcaataa acgaaatcaa ctagtcattg
     7261 aatcaatgca aattagaaac cctgatcatt ttacgagatt aatgggcata taaataaaag
     7321 aagagctgca gtcctaaatg aggattgcag ctctttttgt tttacataga aacaagaaaa
     7381 atgaaaaggc ctttttagga aggcgcaagc gccttctcaa ttgaaaaacc tctctctcac
     7441 tccaaccgcc accgccgttc gagaagaaag gaagtgaacg ttgcacgttc actaagataa
     7501 ggggtcttgc aaagcaagac aaaatagaaa aaacttcctc tcaccaaaag gttcgttcct
     7561 gttcgctatc tctttattga tttgccagac cggcaacaag ttgcctttta tcaccaaaaa
     7621 gcgacaagga caagggtaaa tggcacgctg cacgcccttg tccttgtcgc ttttagttga
     7681 ttcattctgg ccaacaaatc aataaagaaa gaactaacga aaggaagtaa aacctttcct
     7741 aagaggaggc agaatcaatc atgcgaaaga aatttgatta ttggggtgtt cccttcagcg
     7801 aattattccc aaactatcat gcaccatata ctgtcgaatg cgattgtgga gaaagagcga
     7861 aatgtatcaa aagctattgt ttgtatcaat gtccaacatg cgggaaaaaa tataccttgt
     7921 cttatggcga ttatattttg attgatgaga aaggaaagaa acgctgatga aaacacaaca
     7981 caaattattg actgtaaaag aagtcgttca aattttggtg gacaaagaag tcatttctga
     8041 aaaagtagca gaagctttac ttattccgcg gtactggacg atagaaaccc ctttagtaga
     8101 ggatgcaccg actatgctat ttgaagacct agtgaagatt gcaggatatg aactgcatta
     8161 tcaagaaaac atggaaactt atgaaaacga atattggtta accaaattag agaactaaaa
     8221 aggagaaaaa aatatggctc aaaattacta tgacgaattt gtcaaattac ctttggataa
     8281 aatggcacaa aaaatggagg atatgacatt cctatacaat gagacacgtg ttccaaaaaa
     8341 acattataag gaaagattgt cggtagctgt ggaagaaatg attgaatcgg gtgtcgaaat
     8401 gaatctcatt gcgacctact atcgaacgct tgaagaactg aaaaagcaaa atggacaatg
     8461 gtttttccaa gccttactat gcttggaagc aggcgtcaag ccaaacacta tcaaaccttc
     8521 tgaataccaa gctttagaac taacgtatgg gaaatttgtc gaaacgaaaa aagccaagac
     8581 tgtttcaagt gaatggttgg actacttaga aaatgtcaac aagtatggcg catgttacat
     8641 catgaaaaag gaggacaacg aaaatgaata aggtgattta tcaactaaca acggaagatg
     8701 tgtcacactt tttaacaaac aaagaacatt tgaatgaagt aatcagacgg attcaaaaag
     8761 actttagttg tatggaagaa atgaagtact ttattcaaag agtcgaagaa caattgtatt
     8821 tggaaagtga aacgagtcaa acgaaggtta cagtcagcaa taattattta gacgtgtata
     8881 aacgtcgtcc tgacacatta aaaaaaggag cggagcttct acgactagaa acagaaaaat
     8941 atatcatgaa tgtttaccta gaaaggagtg aactggtcga aaactttgtc agctacacga
     9001 tttgcaggaa acactattac tcagaatcag aatattattc aatttttgag agcatggaat
     9061 taatggaaga gctaaacagc aaagatgcga cggtagacga ttattacctt gtatttacta
     9121 aatttttgac gtgtgggacg gaatctatcg tgttaatggg aatggattat gaactcgctg
     9181 tacccgaagt atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
     9241 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
     9301 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa ggtcaataac
     9361 catttatacc gaaaagtgag aatgtgtgaa ataaaaacaa aaaaccttga aattaaggga
     9421 atggttctta tttcgcacca atcgctccaa ccgcccccgc cgcttaggtg gtgcgaaata
     9481 agcgagcaaa gcccgaaaac ctaagagaaa gaaggagatt tatatgaaca aaattattcc
     9541 cttattatta gtcctatttg ttggagaaat acttatgcga cttagtgcag ctgtacattt
     9601 aaacctcgca gtatttttgg taatactaat gttttgtttg atcttttggc gatttgtatt
     9661 agccctcgta agtctactat tcaagatgat tgcagccata tttttcatag gattatttcg
     9721 atgaaaggag agagtaccaa tgccaattgc aataggaaat aaacggttac ccgtgacgtt
     9781 ggatgaaaag agacaaaaag aattgcagta accaaagcag aagtacggca aaagtgaatc
     9841 caggattatg tgtattgcgt tagatttatt gattgcgcaa gaaaaagcag gatttgacat
     9901 accagcactc aaaaagtgat cgcactttgc gcacgtgtta atacgtgtta taattatttt
     9961 gtaaggaggt atagtgcaca atgccactta cgggaaaaga aatgcttaag ttattgaaaa
    10021 aaatggctgg gttgagcgaa ggcaagaggg atttcatcat catctttata aggatggtgt
    10081 tagaatcact gttcctgttc atgccaatca agatcttggc cgaggacttg agcgaaaaat
    10141 tttaaaggat gcgggattga aataatctcg cattcgatta aagaaaggat tgactgaaat
    10201 gttaagtgag cctttagcaa aaacctatcc tgctattttt agcccagaag aaggtggtgg
    10261 gtactttatt gaatttcctg atgttcaagg tgcttacaca ggaattaacg aagacgatat
    10321 atcttatgga attgctatgg cacaagaggt gttaggtatg gttttagcag attatattga
    10381 gcatgaagat ctacttccag aaccaacacc aatcaataag atttctgttg aagatgattc
    10441 ttttactact ttaattcgtg tagatgttgc caaatatttg aaagacacag aacttgtcaa
    10501 aaaaacctta acaattcctc aatgggcgga taagctaggc aaaagggctg gcataaattt
    10561 ttcagtcctt ctaacagaat caattgcaga taaagcagat aacattcttc gttctggaag
    10621 aaataattag aactcaaaag ggtcagaaac ttaaaaatct ttggcttctt tttttactac
    10681 aaagatggct tctttaaatt atttgcctga ttgatttaaa aaaattgcgc aaagactacg
    10741 agctaattaa gttgctcgtg gtcttttttt atgaaaactt tttagatc
//
LOCUS       DBGZHO010000079        10552 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.082, whole genome shotgun sequence.
ACCESSION   DBGZHO010000079 DBGZHO010000000
VERSION     DBGZHO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.082"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            33..656
                     /locus_tag="ACN3HL_002485"
     CDS             33..656
                     /locus_tag="ACN3HL_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007295.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACN3HL_002486"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACN3HL_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8007296.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACN3HL_002487"
     CDS             2152..3033
                     /locus_tag="ACN3HL_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007297.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACN3HL_002488"
     CDS             3036..3806
                     /locus_tag="ACN3HL_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007298.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACN3HL_002489"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACN3HL_002489"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HHC8007299.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACN3HL_002490"
     CDS             5117..6280
                     /locus_tag="ACN3HL_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HHC8007300.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACN3HL_002491"
     CDS             6397..6807
                     /locus_tag="ACN3HL_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HHC8007301.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACN3HL_002492"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACN3HL_002492"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HHC8007302.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACN3HL_002493"
     CDS             9380..9664
                     /locus_tag="ACN3HL_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007303.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="ACN3HL_002494"
     CDS             9824..10060
                     /locus_tag="ACN3HL_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HHC8007304.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="ACN3HL_002495"
     CDS             10057..10455
                     /locus_tag="ACN3HL_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HHC8007305.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3680 a         1770 c         2230 g         2872 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aa
//
LOCUS       DBGZHO010000080        10496 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.083, whole genome shotgun sequence.
ACCESSION   DBGZHO010000080 DBGZHO010000000
VERSION     DBGZHO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.083"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(1..460)
                     /locus_tag="ACN3HL_002496"
                     /pseudo
     CDS             complement(1..460)
                     /locus_tag="ACN3HL_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACN3HL_002497"
     CDS             complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACN3HL_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HHC8007306.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACN3HL_002498"
     CDS             complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACN3HL_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HHC8007307.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACN3HL_002499"
     CDS             complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACN3HL_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HHC8007308.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1964..2089)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2240..2872
                     /locus_tag="ACN3HL_002500"
     CDS             2240..2872
                     /locus_tag="ACN3HL_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HHC8007309.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2874..3779)
                     /locus_tag="ACN3HL_002501"
     CDS             complement(2874..3779)
                     /locus_tag="ACN3HL_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HHC8007310.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3864..4523)
                     /locus_tag="ACN3HL_002502"
     CDS             complement(3864..4523)
                     /locus_tag="ACN3HL_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HHC8007311.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4839..5783
                     /gene="mvk"
                     /locus_tag="ACN3HL_002503"
     CDS             4839..5783
                     /gene="mvk"
                     /locus_tag="ACN3HL_002503"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HHC8007312.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5776..6753
                     /gene="mvaD"
                     /locus_tag="ACN3HL_002504"
     CDS             5776..6753
                     /gene="mvaD"
                     /locus_tag="ACN3HL_002504"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HHC8007313.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6766..7851
                     /locus_tag="ACN3HL_002505"
     CDS             6766..7851
                     /locus_tag="ACN3HL_002505"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HHC8007314.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7848..8912
                     /gene="fni"
                     /locus_tag="ACN3HL_002506"
     CDS             7848..8912
                     /gene="fni"
                     /locus_tag="ACN3HL_002506"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HHC8007315.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9161..9964)
                     /locus_tag="ACN3HL_002507"
     CDS             complement(9161..9964)
                     /locus_tag="ACN3HL_002507"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HHC8007316.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9984..10307)
                     /locus_tag="ACN3HL_002508"
                     /pseudo
     CDS             complement(9984..10307)
                     /locus_tag="ACN3HL_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10340..10477)
                     /locus_tag="ACN3HL_002509"
                     /pseudo
     CDS             complement(10340..10477)
                     /locus_tag="ACN3HL_002509"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
BASE COUNT         3106 a         2220 c         2008 g         3162 t
ORIGIN      
        1 aatacctaat gacatcaaga tcggcaacac aataactgca atagaaatca ctggtccgat
       61 tcctgtcatc gacatgaata taacagcggt tacaatacat agtaagctca tcgtgattct
      121 tggcttgtcc cctccaagtt caactacctt tcgaatcagg gtagctgcga ttccgctatc
      181 tactagaaca cgcccgaaaa aggcaccaaa gaagacattt accaagatcg atttggcgta
      241 ctcagctggc cccgtcgtat agatatgcgt caacacatca attactcctt gcccttccat
      301 cgccgagttt ggtgaaaacg tgtttccgac tagcgctaat cccatccata cagtagccat
      361 gatgacaaaa gccgaccatc aagttgtagc cttttacaca gtaccagacc atgaaaaaga
      421 atgagataac taacaaaata ccaataataa tatcactcat gttattcctc cgtccatttt
      481 gtttttctga taagcaaact aatatatcag tcaaactcat tctaacttat gtagttagcg
      541 ctttcattaa aggatgacca taaatgttca gttttcaatt aaaaaacctt aattatgtta
      601 ttttagactt atacgttatt gtcctgtttc atttgatgga ggattgtaaa taaaaaaaga
      661 ggaaagaaca taacttttcg ttatcttctt tcctctttat aattgtttag cttatttagc
      721 caaagcttct tttgcttggt cagccaatgc agtaaatgct gctgcatcgt taacagccaa
      781 gtcagctaac attttacggt tgatgtcgat ttcagcaact ttcaaaccgt gcattaattt
      841 tgagtagctc aagccattca tacgagctgc tgcgttgata cgagcaatcc acaatttacg
      901 gaagtcgcgt ttcttttgac gacgatcgcg atatgcgtag ttgtatgaat tcattacttg
      961 ttcttttgct gttttaaata aagtgtgttt tgaaccgtag taaccttttg ctaattttag
     1021 cactctttta cgacgtttac gagttactgt tccaccttta acacgtgcca tgtataattc
     1081 ctcctaataa aaataaatct tcagattctg ttatttgtac ttcttatttc atttttgcta
     1141 gttgttggcg aatacgtttg aagtcgccac tagaaaccat gcttgcttta cgcaattgac
     1201 ggcgttgttt ttttgttttg ccgtggaaac ggtgacttgt aaacgcgcgg aagcgtttca
     1261 atccgccttt accagtacgt ttgaaacgtt ttgctgatcc gcggtgtgtt ttttgttttg
     1321 gcatgactat atttcctcct caaaatcttt cgttatccga ctatcggctg tccaacagcc
     1381 agttagtcat tcaaattact tactgtcgtt tttcggtgcc agcgtcaaga acatgctgcg
     1441 tccgtccatt ttcgcttttt gttccactgt tgcaatatcc gcagtttctt cagctaagcg
     1501 attcaagact ttttgaccaa tttctttatg ggtaatggca cggcctttga aacggataga
     1561 agctttcact ttatcgccct tttccaagaa cttacgtgca ttacgaagtt ttgtattgaa
     1621 gtcattcaag tcgatcgtag gacttaagcg aacttctttt acattgatca ctttttgttt
     1681 tttacgcgct tcgcggtctt tcttttgttg ttcgaaacgg tatttaccgt agtccatgat
     1741 tcgcgcaact ggtggtttcg caccaggggc aactaacaca agatccaagt ttgcttgttc
     1801 tgcaatattc aatgcttctg cttttgtctt aactcctaat tgctcaccat ctgaaccgat
     1861 caatcgtaac tctcgtgcac gaatgccgtc gttaaccatc atatcctttg ctatggtcat
     1921 tcacctccaa atattatgag agaaagaaaa gcttaccgaa taaacggcaa taaaaaaacg
     1981 agttctctta cagaacccgc gcgtacttca cctaatagaa ccagtgaaaa ctatctagcc
     2041 cagtgacatt atcaactaag gcgagaagcg ggtgcttctg cttttatttc tcaaccatta
     2101 tagtatagca aaaactaatc tttttgtcaa tgtttttcat acagtttgtc ttccttttct
     2161 gaaaatgatt agattagcag gctttctagc agtgattccc gcttctttgc tatactaaag
     2221 aaaaacgagg tgaacccaca tgaaaaaaat cgaacctatt ccaccttctc ttcctcttct
     2281 tacaaaggga gagttttatt tagaagatga ggagatcttc tctggtcttc tgatcaacgg
     2341 aggtaaccaa agctatctcg atgccaaaaa tatggtatta agagagagtc atatccaaaa
     2401 acttacgatg caaaaaacag gtttacgtca ttttgaatgc agtaatgtca tttttgaaaa
     2461 atgtgatttt tccaatctgg agtggattgg tggcagtttc caccaagtcg tgtttcatca
     2521 atgtaaatta acaggtacga attttgccga aagttatctt cgagactgta ctttcactga
     2581 ttgtattgct tcgatggctt cctttagtag tacaaacttg aaagctgtct ccttcgatca
     2641 ttgtcaatta gaagacagcg aattttatga ggtcacttgg aaaaaccttt ttttgtctga
     2701 caatcagtta accggttcga actggtttcg aacttctctg aagggattag actttacgac
     2761 taatttcttc acaacaatcg ctttatctca agattctttg gcgggactaa tcgtcaatca
     2821 agagcaagca cttgtgatcg cccaagccct tggtttgcag atcaaagact agatcaacga
     2881 atccgccgcc acagtgcaat aagcatccaa atagataaga ccaaactgat gatcaaggcg
     2941 atttcccatc cgaaaacgga atgggtaaag ggtaactgga gattcattcc gaagaatcct
     3001 gtcacaatag ttggaacggt caagatcagc gaccagaccg tcaaaaattt catcgtgtca
     3061 ttcaagttgt tattcagcaa attattataa gtgccagaga gctggtctaa aatctgcgaa
     3121 gctaagttcg tcatttcaac tgcttgtcgt gcttcgatca gtgcatcgtc caactcttct
     3181 ttttcctttt ctgacaactt gcgataaata gccagtgcct tgatttgttc taaaagtact
     3241 acattttgtt ttgttcctgt aactaagtaa accaaaccga tctctaaatc tgaaagttgc
     3301 agcagattct tgttcgttgt tttttctctt aatttcagat taagccgctg acgttcacta
     3361 ttcacttcct cgattaaagg aaaaaaggaa tcagaaatca aaaacaatgt acgaaacaat
     3421 aaactgtata cactcatgtc tggcatccgt tccaaaagcg atcgaattag tcgaatcacg
     3481 tactcggtat tcggcgtggt aaatgtaaac aaaccgtctt cttttaaaat aaaagcgata
     3541 ggactagttt cataatgatt atcgactttt tgctggtgcg gaacatttga tacaagcagt
     3601 aacgcttcat caaaagaatc gtactctacg cgcgcccgtt catttttatc tagagaataa
     3661 gtcagcatct cgtcactaat gccatattct tcttttaagt ttttaacagc tagcacatcg
     3721 ttttgctgta cattgatcca aaaattacgg tcttgattaa aatagtgttt ttcccgcata
     3781 ctctatcctc ctgacatttg tttccagtat aaagaaaaaa gtcgctcaaa taaaggttta
     3841 ccctttattt gagcaactgt aaatcaaatg gatactttgg tttggcgaat ctctgctaat
     3901 ttttcttcga tcattttcaa gacttcttct tttgcttgag gatcttccac aaaattatag
     3961 cggtctccat cgatttggat ttttggactt tctttgtatt cttcatacca ttgatcataa
     4021 cgtctgttca attctttgta ataatcgtat agacttgggt caaaggacaa ttgttcatac
     4081 gaacgaccac gtttttcgat acgctctaac atcgtatcaa aagatacacg aatatgaact
     4141 aataaatccg gatgtttttt atgggcagca tagggaagtt cttccatcat gttttccagc
     4201 agttcatcat acacacaaac ttctgtttct gttgctcttc ctagatctgc atttagatgg
     4261 aaaagcagtg aatcttcata aatcgaacgg tccaatacat tattgtcatc tttcattgct
     4321 tgtttgatgc ttgcaaaacg tttattcaaa aaataaattt gcagcaaaaa agcatactgt
     4381 tcagggtttg cataaaataa gggcaagact tcattatcat caatcgattc ataaaatgcc
     4441 tgactatcaa agtgttcagc catcatttct gttaaacttg attttccggc accaattgta
     4501 cctgctaaaa cgatcacgct catttacctc cagctcactt catcactaaa tattgtgttt
     4561 aactccaacc ttttttaaat atacccccaa tatctagtag tgtcaattgt attttttcta
     4621 gtcaaagaag aaaaaaagtc aaaaaattct taagaaaaaa gtgttttttc tttagaaaac
     4681 gtattcttag ttttacttct gagatggttt tagtaaaata aaggaggaat gttttttgag
     4741 acccttagtg gacaaaaaaa ttcgtgaagc agcgcaactc gttttgggcg ctttattttt
     4801 tgcttaaaaa tcacttttac gtgagaagga gttagattat ggcaaactat ggccaaggag
     4861 aatcaagcgg aaagatcata ttgatgggcg agcacgcggt tgtttatgga gaaccagcga
     4921 ttgcctttcc tttctatgca acaaaagtca ccgcattcct tgaagagctg gatgcaatgg
     4981 acgatcaact ggtttcttcc tactattcag gaaatttagc cgaagctcct catgcattaa
     5041 aaaatatcaa aaaattattc attcacttaa aaaaacagca tgacatccaa aaaaacttgc
     5101 aactgaccat tgaaagcacg attcctgctg aacgtggaat gggatcaagc gctgcagtcg
     5161 ccacagcagt cactcgtgct ttttatgatt acttagcatt tcctttgtct cgtgaaatac
     5221 tattagaaaa tgtccagctt tcggaaaaaa tcgcccacgg taatcctagt ggaatcgatg
     5281 cagccgctac tagcagcttg cagccgattt attttacaaa agggcatcct tttgactact
     5341 tttctttgaa catcgatgct tttttgattg tcgctgatac aggaatcaaa ggacaaacaa
     5401 gagaagccgt caaagatgtc gctcacctct ttgaaaccca gcctcatgaa actggacaaa
     5461 tgatccaaaa attaggatac ttgacgaagc aagcaaaaca agcaatcatt gagaattcac
     5521 cagaaacgtt ggcacagaca atggatgaat cacagtcact tctggaaaag ctgacaatca
     5581 gcaatgattt tcttaatcta ttgatccaaa cagcaaaaga taccggggca ttgggtgcca
     5641 aattaactgg cggtggacgc ggtggctgta tgattgcatt agcacaaaca aaaacaaaag
     5701 cccaagaaat cagtcaagca cttgaagatg cgggtgctgc tgaaacttgg atacaaggat
     5761 taggagtaca tacctatgtt taaaggcaaa gcacgcgcat ataccaacat tgctctaatc
     5821 aaatattggg gtaagaaaaa tgaagaactc atccttccaa tgaacaacag cctttcgtta
     5881 acattggatg cattttatac agagacagaa gtcatctttt ctgatagcta tatggtagat
     5941 gaattttatc tagatggcac cttacaagac gaaaaagcaa caaaaaaagt cagtcagttt
     6001 cttgaccttt ttcgtaaaga agccggcctc tcactaaaag cttcagtaat cagtcagaat
     6061 ttcgttccta ccgcagctgg attagcctcc tctgccagcg ggctagctgc tttagcagga
     6121 gcttgcaata ctgctcttaa gcttggatta gacgatctct ctctttcaag atttgctcga
     6181 cgcgggtctg gttcagcttg ccgaagtatt ttcggtggtt tcgttgaatg ggaaaaaggc
     6241 catgacgact taagttctta cgctaagcca gtcccttccg attctttcga agacgattta
     6301 gcaatggttt tcgttttgat caacgaccag aaaaaagaag tgtccagcag aaatgggatg
     6361 cgtcgaacag tcgaaacatc cagtttttat caaggctggt tagattccgt tgaaggggat
     6421 ctatatcaat tgaaacaagc aatcaaaaca aaagatttcc aacttctcgg agaaacgatg
     6481 gaaagaaacg gactaaaaat gcatggaacg actttagctg cccagcctcc attcacttac
     6541 tggtctcctg acagcttaaa agcgatggat gcggtgcggc aattgagaaa aaaaggcatt
     6601 ccatgctact ttacgatgga tgctggccct aatgtcaaag ttttagtgga aaacagccat
     6661 ttatctgagg tacaagaaac atttaccaaa ttatttagca aagaacaagt aattactgcc
     6721 catgctggtc caggaattgc gattattgaa taaagggaga tttttatgat tgaagtatct
     6781 gcaccaggca aactctatat tgccggagaa tatgcagttg ttgaaacagg acatccagca
     6841 gttatcgctg cagtcgatca attcgtaaca gtcactgtag aatccgcacg aaaagtcgga
     6901 agtatccaat ctgcacaata tagtgggatg cctgtacgtt ggacaagacg caacggagaa
     6961 ttagttttag atattcggga aaatcctttt cattatatcc ttgctgctat tcgtttgact
     7021 gaaaagtatg cacaagaaaa aaacattctt ttatcctttt atgatctgaa agtaacaagt
     7081 gagttagaca gttcaaatgg ccggaaatat ggattgggtt ctagcggtgc cgtgaccgtt
     7141 gcaacggtca aagccttgaa tgttttttac gcgttgaatt tatctcaatt ggagattttc
     7201 aagattgcag cactagccaa tttagcagtt caagataatg gttcctgcgg cgacatcgct
     7261 gctagctgtt atggtggctg gatcgctttc tcaaccttcg accatccttg gctccaagaa
     7321 caagaaactc agcattctat cagtgagtta cttgccctgg attggccagg tctatccatt
     7381 gagccattga ttgctcctga agatttacgt ttattgattg gttggacggg tagccctgcc
     7441 tctacttctg atttggtcga tcaagttcac cgttcgagag aagacaaaat ggtggcttat
     7501 cagcttttct taaaaaacag tacagaatgt gtcaacgaaa tgatcaaagg gtttaaagaa
     7561 aataatgtaa cgttgatcca acagatgatt cgaaaaaacc gacaattact gcatgattta
     7621 tctgcaatca ctggggtcgt catcgaaacg cctgctttga acaaattgtg taatttagct
     7681 gaacagtatg aaggagccgc aaaatcttct ggtgcaggtg gtggcgattg cggaatcgta
     7741 attgttgacc agaaatctgg catccttcct ttaatgagtg catgggaaaa agcagaaatc
     7801 actccactgc cgttacatgt ctatagcgat caaagaaagg aaaaccgatg aatcgaaaag
     7861 acgaacatgt ttcactagct aaagcctttc atgataaaca aaaaaacgaa tttgacttcg
     7921 tacggatcat ccataaccct ttgccgcaaa tagcagtttc tgatgtcgat ctaagtacac
     7981 aggcagttgg gtttacacta agcagcccat tttatatcaa tgcgatgact ggcggaagcg
     8041 aaaaaacaaa aaaaatcaac caagatcttg caatcgtcgc aagagaagca gatttgatga
     8101 ttgccactgg ttcagtcagc gctgccttga aagacccttc tttagccgat acttatacga
     8161 ttatgcgaca agaatatcct cacgggaaaa tcattgccaa catcggtgca gggacttctg
     8221 tcgaaagagc ccaagaagct atccgattgt ttcacgcaga tgccttacag attcatttga
     8281 atgcacctca agagttggtt atgcctgagg gagaccgtga ttttaccaat tggaaagtac
     8341 ttattcaaga gactcaaaca gccattgacg tccccctcat cgtaaaagaa gtcggttttg
     8401 gcatgacaag agaaacgctc aatgatctag ctgctttagg agttcataca gttgatatca
     8461 gcggtcgaag cggaacaagc ttcacccaga tcgaaaacgc ccgtcgctcc aagcgggaac
     8521 tgagttattt agctgactgg gggcaatcga cagtctcttc attgcttgaa gcaaatgaag
     8581 cagacacttc tatggaaatc ctagcctccg gaggtatccg caatgcctat gacatattta
     8641 aagccctttg tctcggcgca aatgcagtgg gtacttcagg aaccgtactg acgcatctga
     8701 tgaatcacgg cgtagaagaa actattatac tgatgaagca atggcaagaa gagcttcgtc
     8761 tgctttatac tatggtcggc gcaacgaata ccgcggccct acaccaacaa tcactgatct
     8821 tttccggacc agtgaaggat tggtgcgaag caagagggat cgacttagtg aagtatggaa
     8881 gacgcacaga aaagagcgtg ggacaaaagt aaagaacact tttatcccac gctctaaaca
     8941 cgtataaacg gcggaagcaa aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
     9001 tgaaaagcaa ttttcgtgaa ttccttctta tttcttggag ttaaacgctt ctgtcccagc
     9061 ctcttttttc gaataaatga tgtttaatca gctgtccttc ggtattcgtt caagccgctg
     9121 atttcacaac ctctccacta aacggtgtac taaagctctt ttaaggttgt tttccgatat
     9181 aggcaagtat gcctccgtcc acatacaaga catggccgtt aacgaaatca gatgcgctag
     9241 aagccaagaa gacagatggt ccagccaaat cgattggctc gccccagcgt gctgctggcg
     9301 tacgtccaac gataaattga tcgaatggat gacgttcacc gttttcttgt gtttcgcgta
     9361 atggagcagt ttgcggtgta gcaatataac ctggtccaat tccattacat tggatattgt
     9421 attgaccgta ttcagaagcg atgtttttcg tcagcatttt taatccgcct tttgccgcag
     9481 cataagcact gaccgtttcg cgtcctaatt cactcatcat ggagcagata ttgatgattt
     9541 taccgccgcc tttttcgatc atatcccgaa taactgcttt tgaaacgatg aatggggcat
     9601 ttaaatccac gtcgattact tggcggaagt ctgccgcatc catttcgatc atcggtgtcc
     9661 gtttgatgat ccctgcattg ttgactagaa tatcaactga acctacatct tctttgatct
     9721 gttgaaccat cgcttgaacc gcttcttcat cggtcacatc gcagacataa ccttttgcat
     9781 cgatgcctgc ttctttataa tgcgctatac cttcatcaac tgattcttga ttcaagttat
     9841 taaatacgat ttttgctcct gctgtagcta aagagcgtgc aatctcaaat ccaataccat
     9901 agacagcacc ggtgactaat gctacttttc catctaaacg aaacatatcc atactaaatt
     9961 ccatcatttt ctctccctta tgcttatttt aattgatcca tttgcaccat atccatgtct
    10021 gtataggtga tattttctcc gcacattgcc cagatgaatg agtaattgct tgtacctaca
    10081 cctgaatgga tcgaccagct tggcgaaata atggcttgtt cattgtctac gactaaatgt
    10141 tttgtttcat ctggtttgcc catcatatgg aacacacgtg tatcttcatt ggcataatca
    10201 aaatagacat aagcttccat acgacgttca tgtgtatgac aaggcatcgt attccaagca
    10261 cttcctggtt ctaaaatcgt ataacccatt tataaatgac agctatcgct gaagcttcta
    10321 ctgctgtaaa tatccccgtc aagataccac cgataatgat gacaatcaat agaaggctag
    10381 gaatcgcctc ttttattatt tttccagcat gagccatctg tcctttttcg acaacagggt
    10441 atttattctt tttagcaacg atgaatgcta ctagcatgat tcctagcgcc cacaaa
//
LOCUS       DBGZHO010000081        10243 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.084, whole genome shotgun sequence.
ACCESSION   DBGZHO010000081 DBGZHO010000000
VERSION     DBGZHO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.084"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            160..390
                     /locus_tag="ACN3HL_002510"
     CDS             160..390
                     /locus_tag="ACN3HL_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HHC8007317.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            487..1788
                     /gene="murA"
                     /locus_tag="ACN3HL_002511"
     CDS             487..1788
                     /gene="murA"
                     /locus_tag="ACN3HL_002511"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HHC8007318.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1801..1977
                     /locus_tag="ACN3HL_002512"
     CDS             1801..1977
                     /locus_tag="ACN3HL_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HHC8007319.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2112..2408
                     /gene="yidD"
                     /locus_tag="ACN3HL_002513"
     CDS             2112..2408
                     /gene="yidD"
                     /locus_tag="ACN3HL_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HHC8007320.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2592..3059
                     /locus_tag="ACN3HL_002514"
     CDS             2592..3059
                     /locus_tag="ACN3HL_002514"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8007321.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3144..4028
                     /locus_tag="ACN3HL_002515"
     CDS             3144..4028
                     /locus_tag="ACN3HL_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HHC8007322.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4142..4378
                     /locus_tag="ACN3HL_002516"
     CDS             4142..4378
                     /locus_tag="ACN3HL_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HHC8007323.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4466..4546
                     /locus_tag="ACN3HL_002517"
     tRNA            4466..4546
                     /locus_tag="ACN3HL_002517"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4500..4502,aa:Tyr,seq:gta)
     gene            4553..4624
                     /locus_tag="ACN3HL_002518"
     tRNA            4553..4624
                     /locus_tag="ACN3HL_002518"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4585..4587,aa:Gln,seq:ttg)
     gene            4749..4919
                     /locus_tag="ACN3HL_002519"
     CDS             4749..4919
                     /locus_tag="ACN3HL_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007324.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5139..5846
                     /locus_tag="ACN3HL_002520"
     CDS             5139..5846
                     /locus_tag="ACN3HL_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007325.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5906..6550)
                     /locus_tag="ACN3HL_002521"
     CDS             complement(5906..6550)
                     /locus_tag="ACN3HL_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HHC8007326.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6677..6964
                     /locus_tag="ACN3HL_002522"
     CDS             6677..6964
                     /locus_tag="ACN3HL_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007327.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7072..7392
                     /locus_tag="ACN3HL_002523"
     CDS             7072..7392
                     /locus_tag="ACN3HL_002523"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8007328.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7473..8786
                     /locus_tag="ACN3HL_002524"
     CDS             7473..8786
                     /locus_tag="ACN3HL_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HHC8007329.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8783..9502
                     /locus_tag="ACN3HL_002525"
     CDS             8783..9502
                     /locus_tag="ACN3HL_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HHC8007330.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9630..10181
                     /gene="raiA"
                     /locus_tag="ACN3HL_002526"
     CDS             9630..10181
                     /gene="raiA"
                     /locus_tag="ACN3HL_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HHC8007331.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         3415 a         1693 c         2187 g         2948 t
ORIGIN      
        1 ttgtctcagt cccttttttt gcatattttt agcatttatt tcctaaaaaa tgtaagggga
       61 ttcctatatt tttaagtata cttgtttttc cttttataca ttttatggta ttatcatttt
      121 attagttatt ataaaacaat cgttagaaag gacgtcatta tgcaagtata cggaattgat
      181 gcggtgcttc gaatcgtgag tcatttggcg tttatctact tagccttctg gtctttacgt
      241 tcgttacgca ttgaaacttt tttcagacca atgcataata cgcaaattag aatggcaatc
      301 gtactttttt caattttttt agggtacact gcaagtaatt ttttcttaga agttatcgct
      361 ttatgccgaa atcttttcgt tagcctgtaa attttaaaaa aaggtactat tttaaaagca
      421 aggatgttat aatagaaaag attttgagta agtgtatgct cattggaatt ttttggaggg
      481 aacaacatgg aagagatcat cgtaagaggt ggcaatcaat taaatggaac agtaagaatt
      541 gaaggagcta aaaatgctgt tttgcctatt ttagctgcta gtttgttagc agaagaaggt
      601 attacgacat tagacaacgt tccgattctt tctgatgtct tcactatgaa tcaagtgatt
      661 cgtcacttaa acgtagatgt agattttgat gaacaaaaga atcaagtaac aatcgatgct
      721 tcaagacaat tagaaatcga agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc
      781 gttgtgatgg gtccgctact tgccagaaat ggacatgcaa aagtagctat gcctggtgga
      841 tgtgcgattg gtaaacgacc aatcgatttg catttaaaag gatttcaagc tttaggagca
      901 aaaattattc aaaaaaacgg ctatatcgaa gcaattgcgg atgaattgat cggtaacacg
      961 atttatttag atttccctag tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa
     1021 gcaaaaggaa caaccatcat tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca
     1081 aacattttga ataaaatggg cgctcaagtc tatggagctg gtactgaaac aatgcgtatt
     1141 gaaggcgtgg atcatttaca tgcagtcaac cactcaatcg tacaagatcg tatcgaagca
     1201 ggtaccttta tggttgctgc tgcaatgaca caaggcaatg tgctgattgc agatgctatc
     1261 tctgaacata accgcccatt gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa
     1321 gaagaaggcg gagtccgtgt catcggacca aaacatatct tacctacaga tgtaaaaacg
     1381 atgcctcatc ctggtttccc tacagatatg caagctcaaa tgacagctat ccaattagtt
     1441 gcagaaggta caagtgtagt gactgaaaca gtgtttgaaa atcgtttcca acatttagaa
     1501 gagatgcgcc gtatgaacgc tcatgtcaaa atcgacggaa atgtagcaat catggatgga
     1561 aaccatgaat tgcaaggtgc agaagtatat gcaacagact tgcgggcagc agcagcatta
     1621 gttttagctg gcttgaaagc aaatggaatc acacgtgtgc gtaacttgaa ttatctagac
     1681 cgtggatatt ataatttcca tatcaaacta cagcaattag gtgcagacgt tgaacgtgta
     1741 gacatggatc aaacttctgc tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga
     1801 atgagtaacc aacgatatat catattaact ttgataaaga ttttagtggt gatcttattg
     1861 cttatccttc tttttgtggc cggaacgatg atcggatatg gtgtcatcgg tggcggcaat
     1921 ccatttaaag tattccagcc aagtttgtgg attcatattc gagacttttt tcattgataa
     1981 ataagaatca cagtggttct agtcgatatg aagtgagcca tgaagcagaa catgacaaaa
     2041 gaaaacagaa gggaacgttg acgttagtcg cgatcccttt ttttagtaaa agaaaagaag
     2101 gaatctaatt gatgaagaag atattgattt atttagttag aggatatcag cgctttattt
     2161 cgcctgcatt tccacctagc tgccgttatt acccaacctg ttccaattat atgataaaag
     2221 caattcaaac ccatggtgca ctaaaaggga cggtaatggg gactgcacgg atcttacgct
     2281 gtcatccttt tgtcaaaggc ggtatcgatt atgtaccatt gacattccaa ttaacgcgaa
     2341 ataagaaaga taaaaaagaa ccagattata aaaaggttgt gaaaaatacg agtagcactg
     2401 agcgataaag aaacaatttg gaaaatagct tcttatattt tgcaaaattg tgagttattg
     2461 ccgaagtgtt ggattttgaa caccgtcaaa aaaaggttgt gaaaaatacg ggtagcactg
     2521 agcgataaag aaaaagagga aaattattgt caaagtaaca actccgcaac tacttatatg
     2581 ggggacaaaa aatgatcgaa gaactaaaca agaaagattt accatggtcc ttgttattag
     2641 atgcagatcc tgataaagaa aaagttcaag tatatgtttc cagagggagt ggctggatat
     2701 ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt ggcaagggaa aaagaatacg
     2761 aaatcgtcaa tgtagcagta gccccaacgt atcaaggaaa ggggattggc ggaaaattac
     2821 ttgagacagc ttttcagaag ctttcacaac tcgcttccag tcaaactcag atcatcatac
     2881 gaaccggcag tactagcagt gcggcgttac atctctatca aaaaatgggc tatgtggaga
     2941 ttggtcgagt caaagactat tttatccatc attactctga gcccattttt gaaaatggag
     3001 atcaattaag ggatcaagta attttagcaa ttcacttacc taaaaatagc tttaactaat
     3061 aaactttcaa ttcgagaaaa tgctttcaaa tgctaaatag atacattaca atagctttag
     3121 caaacaaaaa ggagaatatt tttatgggaa tattagtttt tgattttggt ggatcggctg
     3181 tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg
     3241 aatcttggga agaaatgaaa gcgcaattat ttcaagttta taaaaaaata ctcgtttctt
     3301 ttgaagtcga aggaattgga atcagctctc ctggagtagt gaataatgag aaacaggtga
     3361 ttgagggaat cagtgcgatt ccttatattc atggatttaa tattttccga gatttggaaa
     3421 ctctgtttca actcccagta acgattgaaa atgacgccaa ctgtgccgga atggctgaat
     3481 tttatgaagg tgctgcccgt gattatcaag atgttgcttt tgttgtggca ggaactggga
     3541 ttggcggggc gttgttcacg aaaggacaaa tcaataaagg ggcacatctt tatggtggag
     3601 aatttgggtt gatgttctta aatggcgata agacattcag taaacttggt acagcggtac
     3661 agatggcttg gcgttattgt gaacgcaaag gtctcgataa aaattcttat accggaaaag
     3721 atgtctttga attagcagaa actggagatg caatagcaaa agaagaagtt gagagttttt
     3781 atacgtatct tacaaaggga ttattcagta ttcaattttc gtttgatcca gaagtgatcg
     3841 tattaggcgg cggtgtttct gcaaaagaag ggctcattga tgagatcaaa agccgaatga
     3901 agaagctgac agaacaattc gatctgcatg atttcgaacc gcagatttta ttatgtgaat
     3961 acagaaacga tgctaatctt gtaggtgcag cagcaaacta tctcgctgta cgtcaagggg
     4021 agaattaaga gctttagaga aggtgcagct tgcataaaag aagtgaatga aatgaatagg
     4081 agatttttac ctaaggaatg ttttatttgc tgcagtatga taaaatatct gagaggtgaa
     4141 aatgatgtca aaaaaaaata aagatgttga agtgcgtata gaagaagtga aaaaagatat
     4201 caaaggtaag aattatgaag tcactcagtt atttataggg aaaaaaatga ttggtgagat
     4261 cttagcctat gggccaaaag aatatgaaat tttctttggt gaagaagatt ttggaaaaga
     4321 aaaaagtctt gaaaatgcga tagaaacagt gattcgacac tggaatctgc acgaataaaa
     4381 aaatatcaaa aaaactttca ataaagggtt gcaaaaatct ggaaaattag gtattataac
     4441 taagtcaggt tgatacaaac ctttcggagg agtagcgaag tggctaaacg cgacggactg
     4501 taaatccgtt ccttagggtt cagtggttcg aatccactct cctccatttc attggggtat
     4561 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
     4621 ccagtatacc acaatcgtaa gctctcgtta gttcgagagc tctttttttt gctttgctac
     4681 cttgttcctt gaagattctg ctgatttaag atagagttaa gttaactaca agaattggag
     4741 ggatccacat gaaatggaaa gaaaaagtag acgaagcagc tgaaaagtta tatgatttgg
     4801 tcaaatcaga aaaatacaat attgaagtga atattccgaa aaaaggcgga aaagcggtcc
     4861 aggtaaaatc aaaacgccca acgaatcata caaaaaaatg gatggctaaa aaccgctaat
     4921 aataacaaaa gatccataag tcggcatttt catcgatttt agggtctttt gttattttct
     4981 aggttgaaca tatctaaaaa attgtttctg acaataggag taggaagaac gatgtgtgtc
     5041 taaatcctct gttgatggat agaaaccttt atctttttca gttgtgaatc aggtatatac
     5101 cagttataat agaagaaacg aaaggacggg tgtacgttat gtcgaatcaa ttacctgtat
     5161 atatacagat tcatgaccaa ttaaaaaatg aaatcgaaca aggtatatgg aaagtcggag
     5221 accgtcttcc ttcagaaaga gaattagcag tgaaattcaa tgtcagccgt atgacgttga
     5281 gacaagcaat tcaaaacttg gcagatgaag gaatcttaga aagaaagatc ggttcgggta
     5341 catatgttgc gcgagaaaaa gtacaagaaa aaatgtctgg tgcaacaagt tttacagaaa
     5401 ttatggaatc gcaaaatcga gtaccgtcta gtcggacaat ctcttatttc ttgacttcgc
     5461 caagctcaag tgaaatggaa aaactaaact tgagtaaaga tgacacgatc ttgcgaatgg
     5521 aacgtattcg tttcgcagat gatgtcccta tttgttttga agttgccagt gtgccacaaa
     5581 agctgatcga tggctacagc aaagcagaga ttactgaatc gttgtatcgc acgctagaag
     5641 aaaaaggcgg gaaaaagatc ggtccagcga atcaaacgat tactgctgtg ttggcttctg
     5701 agaaaattgc tgactattta gaggtaaaac gaggagatgc agttcttcgt ttgcgccaga
     5761 tttcttattt tgaagacggt acgccgtttg agtatgtgcg tacgcaatac gtaggaaatc
     5821 gttttgagtt ttatttggaa aaataaaaaa caggtgatcc ctgattcctt acttagaaat
     5881 aaaagagaat cagaatcacc tgtttttata tatgatcagt taccagttgc tcgtgataag
     5941 aaacaggacc ctcttcaaat tggacttgtc cgttcagcag ctcaatgatg gattctttaa
     6001 agtggtcagc acttttttca tctacagcac agatgacgct aacttgatca gtatattgga
     6061 tttcttttat aaaaaaatgt tggagttcaa gataattctg taattttcct agttgcggat
     6121 acgtgatcat cacagagatc tcctgttgca aggtaccttc tacgattcca atgtcagaca
     6181 atgcttgaga gacagcatga gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc
     6241 ctccaaaata tcgagtgact actgcagcta cattgatcag ttgatttttt ttgaggactt
     6301 ccaacatcgg tacgccagcc gttccacttg gttctccatc atcgctgctt cgctggattt
     6361 catttttttc tccaatgatg aaggcgctgc agttatggtt cgctttccaa tgttcttttt
     6421 ttatttcttg aatgaaactt tttgcttggt cctctgattc tattcgtcta agagaacaga
     6481 taaagcgtga ttttttgatc tcaatctcac tttgtccatt ttcttttatt gtacgatagc
     6541 gctcgatcat cttgtcacct ctttttttca ttttctttat tcagtataaa taaagttcta
     6601 ggttgtttca acactgtaac ggttgcgcaa tcgctgtagt atgcgataat aaagacaaag
     6661 gtaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
     6721 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
     6781 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
     6841 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
     6901 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
     6961 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aatagagtaa
     7021 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa
     7081 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
     7141 caaaaagctg ctgaagcaaa aggaatcgac tcggatattt tcgctgtgtc cgcttctgac
     7201 gcagataaca atcttgcaaa taaagatgta gatgtactgt tattaggacc tcaagttcgc
     7261 tttatgaaag ctgattttga aaaacgtctg gaaccaaaag gcattccttt agacgtcatc
     7321 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc
     7381 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
     7441 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
     7501 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
     7561 tcgcagcagt ggaacgtttg ggcaactgga ttctttgtca tcgctgtgga atgaggacgt
     7621 ccgtcattga tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
     7681 ggcgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
     7741 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa
     7801 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
     7861 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
     7921 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
     7981 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
     8041 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
     8101 atgagatcga tgcgtttcct tataacgggg atgcaggatt agctcatgct gtgcaaacag
     8161 cgattaaacc agacggacga ttcatctact taagtgccac acctgataaa aagttactaa
     8221 aggaaatcaa gcagacgttt gacatccaca aacttgcttt gcgctttcat cggcgtttac
     8281 ttcctgaacc cgtcttggtt ttcatgaata attggcgaca aaaatgcaag aacaagaaga
     8341 agataaaatc tttggtgcgg atcattcatc aattaattaa agaaaaccat atccttttat
     8401 tttgtccaag tatcacgatg atgcatcgtt tgaaagccac acttcaagag gctcttccga
     8461 gatatgagat cacagatgtt tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa
     8521 tgcgagaagc aaaatatgac atactgttaa ccacgatgat ccttgaacgt ggagtcacat
     8581 ttgaaagaat atccgttatc gttttaggag cggatcatcc ggtttttact aaatcttctt
     8641 tggtacaaat cgcaggaaga gccgatcgta aagggcctta tacgaacagt caagtatact
     8701 ttttctatga agaaaaaact gcagctattc gaaaagcttg tcaggaaatc aaagaaatga
     8761 atgaagaagg gaagaagatg ctgtgaggtg cagttgctgc agtaaagata tcgtccaaaa
     8821 tttaacattc agcgagatta ttggtgtttc gaaatacaga ttacctcaga cttgttcagt
     8881 ttgtcgcgca caatttcatt tattggaaac aagaggctgt tctggctgtc aaaaaccaat
     8941 ccatttcaat ctagagagta cgaaaaagaa agtaaagtct attcccgttt actgcagtga
     9001 ctgtcaagaa tggaagaaga aatatccgac ctatgatttt cagcaccgtg ccttttttgt
     9061 gtacgatgaa aatatgaagg cctggctcaa tcaatacaag tttatgggag atatccgact
     9121 agcaggcacc tttgcatata aatggacgca gataaaaaaa gaatacccga catacatcta
     9181 ttgtccaata cctttatctg aaaaaaggcg aacagaaaga ggattcaatc aagtaagcga
     9241 gatgttgaaa gcagcaagaa ttccttttca gatgctactc aaaagagaga agcatctgct
     9301 ggctcaagca aaaaacacgc gaaaggaaag attggagatg cctcaacctt ttgaacttgc
     9361 agtcaccttt tctaagatac aaaataaaaa aatattgatt attgatgatg tctatacaac
     9421 aggacagact cttttccacg cagcagattg tttgcaggtc gcacagccga aaatcatccg
     9481 aaccatttct ttagcaagat gaattagatg tggaaatttg atagcgattt aatttgcaaa
     9541 taacctagag ttcgatataa tagaattaag aagagggaaa gagtggtcct tctccttctt
     9601 gattgtggta gacgaaaggg gtaattttta tgtttagata taatgtacgc ggcgaaaata
     9661 tcgaagtaac tgaagcgatt cgcgactacg ttgagaaaaa agtaggcaaa ctagaacgct
     9721 atttcagtga cgcacccgat gcaacggcgc atgtgaactt aaaagtttat acagaaaaaa
     9781 cagcaaaagt ggaagtaacg atcccattac cttatcttgt attacgtgcc gaagaaactt
     9841 ctccagattt atacgcaagt atcgatttgg ttgttgacaa attggaacgc caaatccgca
     9901 aattcaaaac aaaaattaat cgtaaatccc gtgaaacggg catgaatact gcagatgcta
     9961 ctgctttatt caatgaagag gacgaaaacg aaaatgattc tgaattagat atcgtacgta
    10021 cgaaacgcct ttcattgaaa ccaatggata gtgaagaagc agtcttacaa atgaacatgc
    10081 tgggacataa cttctttatt tttgaagatg cagaaacaaa tggtacaagt atcgtttacc
    10141 gccgtaaaga tggaaaatac ggactgattg aaacagactg atcagcctta cttaaataac
    10201 aacgaaaact tgcagcagct actgacagct gccgcaagtt ttt
//
LOCUS       DBGZHO010000082        10220 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.085, whole genome shotgun sequence.
ACCESSION   DBGZHO010000082 DBGZHO010000000
VERSION     DBGZHO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.085"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="ACN3HL_002527"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="ACN3HL_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HHC8007332.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="ACN3HL_002528"
     CDS             complement(2020..2922)
                     /locus_tag="ACN3HL_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8007333.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="ACN3HL_002529"
     CDS             complement(2919..3611)
                     /locus_tag="ACN3HL_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HHC8007334.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="ACN3HL_002530"
     CDS             complement(3654..4295)
                     /locus_tag="ACN3HL_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HHC8007335.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="ACN3HL_002531"
     CDS             complement(4333..4647)
                     /locus_tag="ACN3HL_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007336.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACN3HL_002532"
     CDS             complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACN3HL_002532"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HHC8007337.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACN3HL_002533"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACN3HL_002533"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HHC8007338.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="ACN3HL_002534"
     CDS             complement(5984..6916)
                     /locus_tag="ACN3HL_002534"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HHC8007339.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="ACN3HL_002535"
     CDS             complement(6913..7689)
                     /locus_tag="ACN3HL_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HHC8007340.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..>10220)
                     /gene="carB"
                     /locus_tag="ACN3HL_002536"
     CDS             complement(7743..>10220)
                     /gene="carB"
                     /locus_tag="ACN3HL_002536"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HHC8007341.1"
                     /translation="FDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALKIEGG
                     CNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEMKNPV
                     TGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEESLLKA
                     VRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELADLTKI
                     DLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQMRKE
                     NDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQGVEF
                     DYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIELEQPI
                     GVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQPLGDT
                     ATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEHPVLV
                     DRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKKTIED
                     YTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIATKAI
                     LGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSDRQLD
                     KALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAAYFEK
                     NGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREAVEHG
                     IPLFTSLDTADAIVRVMESRAFSTNPI"
BASE COUNT         2922 a         2291 c         1801 g         3206 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa
//
LOCUS       DBGZHO010000083        10050 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.086, whole genome shotgun sequence.
ACCESSION   DBGZHO010000083 DBGZHO010000000
VERSION     DBGZHO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.086"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..722)
                     /locus_tag="ACN3HL_002537"
     CDS             complement(<1..722)
                     /locus_tag="ACN3HL_002537"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HHC8007342.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="ACN3HL_002538"
     CDS             complement(727..1494)
                     /locus_tag="ACN3HL_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8007343.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="ACN3HL_002539"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="ACN3HL_002539"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HHC8007344.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="ACN3HL_002540"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="ACN3HL_002540"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HHC8007345.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="ACN3HL_002541"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="ACN3HL_002541"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HHC8007346.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="ACN3HL_002542"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="ACN3HL_002542"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HHC8007347.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="ACN3HL_002543"
     CDS             4894..5211
                     /locus_tag="ACN3HL_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHC8007348.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="ACN3HL_002544"
     CDS             5211..6917
                     /locus_tag="ACN3HL_002544"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HHC8007349.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVVSNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="ACN3HL_002545"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="ACN3HL_002545"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HHC8007350.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="ACN3HL_002546"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="ACN3HL_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="ACN3HL_002547"
     CDS             8782..9681
                     /locus_tag="ACN3HL_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HHC8007351.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3172 a         1692 c         2012 g         3174 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 tttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gttttggaat ggcaacagtt tttttgacaa
//
LOCUS       DBGZHO010000084         9584 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.087, whole genome shotgun sequence.
ACCESSION   DBGZHO010000084 DBGZHO010000000
VERSION     DBGZHO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.087"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            333..947
                     /gene="gmk"
                     /locus_tag="ACN3HL_002548"
     CDS             333..947
                     /gene="gmk"
                     /locus_tag="ACN3HL_002548"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HHC8007352.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            952..1257
                     /gene="rpoZ"
                     /locus_tag="ACN3HL_002549"
     CDS             952..1257
                     /gene="rpoZ"
                     /locus_tag="ACN3HL_002549"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HHC8007353.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1510..3918
                     /gene="priA"
                     /locus_tag="ACN3HL_002550"
     CDS             1510..3918
                     /gene="priA"
                     /locus_tag="ACN3HL_002550"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HHC8007354.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3933..4424
                     /gene="def"
                     /locus_tag="ACN3HL_002551"
     CDS             3933..4424
                     /gene="def"
                     /locus_tag="ACN3HL_002551"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HHC8007355.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4417..5355
                     /gene="fmt"
                     /locus_tag="ACN3HL_002552"
     CDS             4417..5355
                     /gene="fmt"
                     /locus_tag="ACN3HL_002552"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HHC8007356.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5355..6713
                     /gene="rsmB"
                     /locus_tag="ACN3HL_002553"
     CDS             5355..6713
                     /gene="rsmB"
                     /locus_tag="ACN3HL_002553"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HHC8007357.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6726..7466
                     /locus_tag="ACN3HL_002554"
     CDS             6726..7466
                     /locus_tag="ACN3HL_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HHC8007358.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7463..9532
                     /gene="pknB"
                     /locus_tag="ACN3HL_002555"
     CDS             7463..9532
                     /gene="pknB"
                     /locus_tag="ACN3HL_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HHC8007359.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
BASE COUNT         3205 a         1780 c         2139 g         2460 t
ORIGIN      
        1 gtattaagcc aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata
       61 ctcgaaacta atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg
      121 cgataataac cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat
      181 tacttgatgc aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt
      241 tctagctata attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata
      301 agtacaaaaa gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt
      361 tgtctggtcc atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg
      421 ataatgattt tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg
      481 aaggcgttga ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag
      541 agatgctgga atacgcagaa tatgtcggga attattatgg aactcctttg tcatatatca
      601 acaagacatt ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac
      661 aagtcaaaga aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg
      721 aattaaaatc acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaagaacgaa
      781 tgaaagttgc aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg
      841 atgaagtgcc gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag
      901 tagatcgcgt aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta
      961 aaaccttcaa ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta
     1021 gcaagtaaac gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat
     1081 tcagtaaaaa gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat
     1141 ccacatcctg aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa
     1201 aaagagcgtg aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa
     1261 agaaaaatag agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat
     1321 tcgccactta ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt
     1381 ttcttatctg ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat
     1441 ctctagtaaa ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg
     1501 aaacgaacca tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat
     1561 cagccattca cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga
     1621 gtagaagtcc cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa
     1681 aaatcagaag aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct
     1741 ccggtggtca atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca
     1801 ttcaaaatca cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa
     1861 ttgatctatc ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg
     1921 atttcctgga aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa
     1981 gagcaattag tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt
     2041 ttggtccgtt ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa
     2101 aatgccaaga aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca
     2161 attgcttatt tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag
     2221 ggctggctgg agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt
     2281 gaccaaacga cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc
     2341 acagcaggtc agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg
     2401 aaaacagaag tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt
     2461 atgttagtgc ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc
     2521 ggagaatcag ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg
     2581 cgcaagattg agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc
     2641 ccgctgaaaa atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa
     2701 gatgagacac cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat
     2761 tgcccaatag ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa
     2821 ggcgtttatc agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct
     2881 attgagatcg tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct
     2941 aatttgcagg aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc
     3001 aatcgtcgag gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt
     3061 cctaattgcg atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat
     3121 tgcggacatg aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc
     3181 tactatggaa caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct
     3241 aggattttgc gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta
     3301 caaaaattcg gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt
     3361 ttggactttc cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta
     3421 ccggattttc gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca
     3481 gggcgagcgg aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc
     3541 atagaattag ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg
     3601 catcgtggag gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa
     3661 gaacaagtag cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc
     3721 cctcaaagct tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat
     3781 tattatcaac taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa
     3841 attttgaatg gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa
     3901 ccattaaact ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta
     3961 atgataaatt aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt
     4021 tattagacaa tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc
     4081 aagtaggaca aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac
     4141 tgattaaccc agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca
     4201 gtattccgca tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg
     4261 atcgagacgg agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc
     4321 atgaaatcga tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg
     4381 aagaagaact tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc
     4441 acacctgctt tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag
     4501 gcagtggtaa cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg
     4561 gtaaaagaag cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt
     4621 tcgccagaaa tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt
     4681 ggccaattct tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat
     4741 gcttctttac ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg
     4801 gagaaagaaa ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc
     4861 tatgcgcaag aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag
     4921 cttagccttt taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa
     4981 aaaccagtac ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa
     5041 gaagcaatcg attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt
     5101 ccttggccaa ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa
     5161 gtattggcag aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat
     5221 ctatggattg cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt
     5281 aaaggaaaac aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt
     5341 cagcaggtga aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg
     5401 cattactgac attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg
     5461 agatgatcaa acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct
     5521 atggtacgat tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag
     5581 caaaaaaagt ggatgactgg gtcaagacgc ttctttatct ttctgtatac caattagaat
     5641 ttttagataa agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa
     5701 aaggaaatcc tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag
     5761 gagcaccaga tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc
     5821 tgcctctatg gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc
     5881 tcggtttatc gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt
     5941 ccagagatca ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag
     6001 tcagtccata cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg
     6061 atggcgtcat gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg
     6121 agcctgaaca tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg
     6181 cttctttttt agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca
     6241 aagtcaaact cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc
     6301 aaaagatgga tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt
     6361 tagtagacgc gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata
     6421 aaaaacagcc ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct
     6481 gcgcaccaac tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag
     6541 aagaaaacca agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg
     6601 atgttttgac caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc
     6661 cgcatcagtt ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg
     6721 aaaaaatgca gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact
     6781 atgccagtgt atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg
     6841 gtggtcatcg tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt
     6901 gggaaaaaca agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc
     6961 aagaagaaaa tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg
     7021 gaacaacaat cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg
     7081 atagcagagc ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt
     7141 tagtcaatga actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa
     7201 ggaaaaatat tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta
     7261 ctcatctttg gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc
     7321 tgtctgaaga agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa
     7381 ctgagctgat tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta
     7441 tcgaatataa ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca
     7501 aatcactgga aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat
     7561 cttggatcgt gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc
     7621 gattcgacga tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt
     7681 tagtgtttac gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa
     7741 aggaatggac ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt
     7801 aaatattatg cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca
     7861 ccgagatttg aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga
     7921 tttcgggatt gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctggg
     7981 atctgttcat tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga
     8041 tatttatgct ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg
     8101 tgaatctgct gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc
     8161 acttgatcca aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga
     8221 acctgcagac cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc
     8281 accagctcgt gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt
     8341 tatcacaccc cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc
     8401 aaaagacaag ccagaaaacg aaaccttgcc agaggaggaa gaagttctgc ctgatcctaa
     8461 aaagaaagga cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat
     8521 cggaacagct gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc
     8581 tgatctttct gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac
     8641 aaaaacagaa gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc
     8701 ggcagcggga acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac
     8761 gaaaaaaatc aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt
     8821 gaaagaatta gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt
     8881 agaaagcgga atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac
     8941 agacacgatt actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt
     9001 aggagaaaac tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa
     9061 tattagtgct acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga
     9121 tccagcctcg ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg
     9181 aacagagcct aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt
     9241 agctagtgtc ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga
     9301 taaagataaa gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt
     9361 tgtgaacgta atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc
     9421 ttcagacagt tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga
     9481 atcttccagc tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa
     9541 taaaatatat cagaagggaa tgcgacattg atttgttgca ttct
//
LOCUS       DBGZHO010000085         9571 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.088, whole genome shotgun sequence.
ACCESSION   DBGZHO010000085 DBGZHO010000000
VERSION     DBGZHO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.088"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            130..951
                     /gene="racE"
                     /locus_tag="ACN3HL_002556"
     CDS             130..951
                     /gene="racE"
                     /locus_tag="ACN3HL_002556"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HHC8007360.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            954..2309
                     /gene="rph"
                     /locus_tag="ACN3HL_002557"
     CDS             954..2309
                     /gene="rph"
                     /locus_tag="ACN3HL_002557"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HHC8007361.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            2310..2828
                     /locus_tag="ACN3HL_002558"
     CDS             2310..2828
                     /locus_tag="ACN3HL_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HHC8007362.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            2935..3435
                     /gene="cbpB"
                     /locus_tag="ACN3HL_002559"
     CDS             2935..3435
                     /gene="cbpB"
                     /locus_tag="ACN3HL_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HHC8007363.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(3715..4635)
                     /locus_tag="ACN3HL_002560"
     CDS             complement(3715..4635)
                     /locus_tag="ACN3HL_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HHC8007364.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            4761..5813
                     /locus_tag="ACN3HL_002561"
     CDS             4761..5813
                     /locus_tag="ACN3HL_002561"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HHC8007365.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(5923..6678)
                     /gene="fabI"
                     /locus_tag="ACN3HL_002562"
     CDS             complement(5923..6678)
                     /gene="fabI"
                     /locus_tag="ACN3HL_002562"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HHC8007366.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            6898..7338
                     /gene="fabZ"
                     /locus_tag="ACN3HL_002563"
     CDS             6898..7338
                     /gene="fabZ"
                     /locus_tag="ACN3HL_002563"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HHC8007367.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(7453..8214)
                     /locus_tag="ACN3HL_002564"
     CDS             complement(7453..8214)
                     /locus_tag="ACN3HL_002564"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HHC8007368.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            8403..9497
                     /locus_tag="ACN3HL_002565"
     CDS             8403..9497
                     /locus_tag="ACN3HL_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HHC8007369.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         3109 a         1679 c         2006 g         2777 t
ORIGIN      
        1 aagtcacaac cgcttttcct ctttccattc gaaaaaaaga gatttcgatt gttttaagca
       61 agtaagagca cttgaaaatt cacgctaaaa agtacacaat agggaggata gaatttattg
      121 aaaaaaagga tgatacgatt gacagataat cgccctatcg gatttattga ttcaggtgtc
      181 ggcggcttga ctgtagtaaa agaagccctg aaacaattac cgaatgaaaa tattttattt
      241 gtaggagaca cagcacgctg cccatatggc cctagacccg cggaacaggt aatccagtat
      301 acttgggaaa tgacggatta tctggtggag caaggaatca agatgctggt gatcgcctgc
      361 aataccgcaa ctgcggtggc tttagaagaa atcaaagctg ctctttctat tccagtcatc
      421 ggtgtgatcc ttcccggtac tagagcggca gtaaaaaaaa cacaaaataa acaagttggc
      481 attatcggta cgattggtac ggtaaaaagt caagcttatg aaaaagcact gaaagagaaa
      541 gtaccagaat tgactgtgac aagtcttgct tgtcccaaat ttgtttcagt tgtcgaaagt
      601 aatgaatacc attcatcggt ggcgaaaaaa attgtggcag aaacattagc tcctttaacc
      661 actaaaaaaa tcgatacatt gattttggga tgcacccatt atccattatt acgccccatc
      721 attcaaaatg taatgggaga aaatgttcaa ctgatcgatt ctggagcaga aacagtaggt
      781 gaagtatcta tgctgttaga ttatttcaat ttgagcaatt caccgcaaaa tggtcggaca
      841 ttatgccagt tttatacaac tggctctgcc aaacttttcg aggaaatagc tgaagactgg
      901 cttggaatcg gacacttaaa tgtagaacat atcgaattgg gaggaaaata aggatgcgtc
      961 atgacgggag aaaagcccaa gagcttcgca aactggagct tcaaacaaat gttttcaaat
     1021 atccagaagg atcggtagtg atccgttttg gtgatacaac agttatttgt tctgcaacaa
     1081 tagaaaattc tgttccccct tttttgagag aaacaggaac aggatgggtg acagcagaat
     1141 atagtatgct gcctcgagca acgagtacga gaaatcgtag agaaagcagc aaagggaaac
     1201 tttctggtag aacaatggaa atccagcgtc ttattggtcg ttccttgcgt gcagtagtag
     1261 acttggaaaa attaggagaa cgtagtatca tcgtagactg cgatgtgatc caagcggatg
     1321 gcggtactag aacagcaagt atcactgggg catttgtggc attgaaatta gccattgaaa
     1381 aacttttaag agaaaaagaa ttgtcagaag atccaataaa agaacatctt gctgcagtta
     1441 gcgtaggaat cttaccagat gggacttgcg tcacagattt ggattaccaa gaagattccg
     1501 cagcacttgt agacatgaat cttgtaatga cagaatctgg aaaattcgtg gagattcaag
     1561 gaactggaga agaagcaacg tttgatggtg aacagttgaa tgaaatgctc ttttttggaa
     1621 aaaacgcgat tgaagatttg atcaaagagc aaaaacatgc tttgctaaca gagtttgctc
     1681 aaaatgatga gcggatagaa gaaacaaaaa caatcatcat tgcgacaaga aatccaggaa
     1741 aagcagaaga gtttcgaaat atgttcaaag aagcgggata tcatgtaaaa acattacttg
     1801 actatcctga attgccagat gtggaagaaa ctggcagcac atttgaagaa aatgcccgat
     1861 taaaagcaga aacgattgca caattgcttg atcagccagt cttagcagat gattcaggtt
     1921 tgaaagtgga tgctttaggc ggtatgccag gaatctattc tgcacgtttt gcaggggaac
     1981 aaaaaagtga tgcggggaat aacgccaaat tattatatga attgacagat gtgccggatg
     2041 aaaaaagaac agcacaattc cattgtacgt tagtattcgc ggcacccaaa aaagacagcc
     2101 ttgtagtaga agcggaatgg cccggtcgag tagcccgtat accatctggc gaaaatggct
     2161 ttgggtatga tcctttattt atcccagaag gtaagaaaca aacagcagca gaattatcga
     2221 gcgaagaaaa aaacaagatc agtcatcggg ctcaagcaat gaaaaaattg agtgccgagt
     2281 ggaaacaatg gctggaagga gagagataga tgcggtattt agtagtaagt gataatcatg
     2341 gagacagaga tatcctcgtt gacttagtag atcgttatcg ttctgaagtg gatatctttt
     2401 tccattgtgg tgattcggaa ttagaagctt ctgacccatt atgggataca ttccaagtgg
     2461 ttcaaggtaa ttgtgattat ggaccaggat tcgaacagaa aaaagtgatc caaactggtc
     2521 aggatacagt attcatgact cacggtcatt tatcgaatgt ccgatttggt ttgacacagt
     2581 tagcaatcga agctcgagct gcaactgccg atatggtgtt ttttggtcat acccatcaaa
     2641 taggctgtga gatggatcag aaaatcctgt ttttgaatcc tggtagcatt tctcagccta
     2701 gaggcccgat ccaaatccca tcatatgctc ttatcgaaag tttagatgac caaatttctg
     2761 ttcaatacta taaccgtgcc catcaggcag ttgaagagtt ggccttttct ttttcgagag
     2821 agcgctgaat aaaaaaactc taatttttaa taaaaataag ctttatttta tgaattttgc
     2881 atccggtttc ggtaaaatag tagtgttgaa tgaaatagaa atggaggcca tcagatgatt
     2941 ggacctatag taagagaaat gctgctggaa aatcaggaaa cgtttttgat tcctgcagaa
     3001 aatgtggcaa atgttatgta tcatcatcca ttgtcccatg gtttacttgt gttatcgaag
     3061 gtcggttatt ccaaaattcc tgtattagga aaagatgatc actttgtagg actagtaagt
     3121 ttatcagatg tggtcaataa aatgattgac ttgcaaacaa tcagcatgga cccgttagaa
     3181 ggactaacgg ttgctgatgt gacagaaaca gatgttccga caattgatga aaattgggaa
     3241 ctagaagaag tactccattt gttagtcgat tcgccttttt taccggttgt cacagaagat
     3301 cggattttca aaggaatcat tacaagaaaa gagctgctta aagccgtaaa cttcatggtg
     3361 catgaattag aacgtcgtaa tatattgtct ccgaaaatcg aagaattaaa agaacaaatc
     3421 gatatcgtga gctaaagaac gagaaactaa aagataatca aaaaataagt agaaaaaaca
     3481 gcgtaccagt tttgacttta tcttgaaaaa gaggctggga caaaagcgtt taactccaag
     3541 aaataagaag gaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc
     3601 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgggac aaaagtgttc
     3661 tttacttttg tcccacgctc tttttagtga gattcgttgc atcgtttgtc caaattattt
     3721 tccgacagca attggactgt tcggaatcgt gaaaccagaa gctgtcaatt ctttgacata
     3781 ggagctcaag aactcttctt ttaaggcata ttgttttccg ttcaatgcgt agcagaccgt
     3841 acgaatcgca aaattgctgt ttccaagatc cactaatcca aagatagaag gttcagtttg
     3901 gagctcttct tggtattttt cagctaatgt acgatttact cgatcaatga tctcatagat
     3961 tttgtcatat ccttcttcag gaacaatccg aatatctaaa agtacttgca tatttgcacg
     4021 agagagattg ctgatcgtgg tgatgtttcg attcgggatg aaatggacag taccatccgt
     4081 tgctttcagc tgaagggtac ggataccaac agatacgacg gttccttcaa tcgttaagtt
     4141 tgctagcttg atgtagtccc caacatccat ctgttgttcc atgataataa aaaatccggt
     4201 aataacatca ctcatgaacc cttgggcacc aagaccgatt gccacacctg caattccggc
     4261 accagccaaa agtgatccga tcggcacacc gatagcagat aaaattgcat agataaaaaa
     4321 gaaaccaagg gtataatgaa aaatagtatt taaaagacta tgtaaagtct ttaagcggct
     4381 ctcgtttaga atggcttttt tagaatactg attaaaagac ttatcaatca gatattttcc
     4441 cacacggtga agaatccaaa aaaggacgat caaaaaaatc agatataaac ttttttggat
     4501 aaaggcagcc aaaatggcgt cccaatcaat cccgtcccaa aaccgctgaa acgcatttac
     4561 tttgctgaca gcttgatctg tcaatgtctc gccagaagag tctgtcgtac cggcagttgc
     4621 taataatgaa aacataaaat cctcttttct aaaatttgat tctttctgta ttgtaccaag
     4681 aagttttcaa aaaaggaaat agcaaaaata actataatga aggaaaaaag ctgaaaataa
     4741 aatgacaaat aatatggata atgataaaat gtggagaaaa taacgaaggt ggtaagtata
     4801 tgcaaatcga ttggaacaat ctaggttttt cttatatcaa aactccttgg cgttttattg
     4861 ccaaatggaa agacggacaa tgggaagaag gagaattgac agaagataat tacctgacga
     4921 ttcatgaagg ctctccagcg cttcattatg gtcagcaatg ttttgaaggt ctaaaagctt
     4981 atcgtcgaaa agacggcaag gtcaatctct ttcgacctga acaaaatagt cgacggatga
     5041 atcaaagtgc tagacgattg ctgatgccaa tggtccctga aaagatgttc gttgatgctg
     5101 tcaagcaagt ggtaaaagca aatgaagatt ttgtgccgcc ctatggaaca ggcgctacat
     5161 tatacttgcg ccctttactg attggggtcg gtgaaaacat tggtgtccat ccagctccag
     5221 aatatttatt tgtcgtcttc tgtacgccag taggagcgta tttcaaaggt ggactaaaac
     5281 caacgaattt tattgtatct gattacgatc gtgctgctcc taaggggact ggtgcagcaa
     5341 aagtcggcgg aaattacgca gcgagtttac ttccaggaac agaagcaaaa gaactggatt
     5401 actcagattg tgtttatctt gatccagcca cacatacgaa aatcgaagaa gtaggtgcag
     5461 caaatttctt tggaattaca aaagacggaa aattcatcac tccgcaatcg ccctctatct
     5521 taccaagtat cacgaaatat tccttgttgc agttagctga agaacgacta ggactgcaag
     5581 caattgaagg agatattttc attgatgatc tagatcaatt tgcagaagct ggtgcatgtg
     5641 gtacagcggc tgttatttct ccaatcggtg ggatttatca caataacaat cttcatgtat
     5701 tttatagtga aacggaagta ggaccagtaa caaaacggtt gtatgatgaa ttgacaggta
     5761 ttcaatttgg agacatagaa gcaccagaag gctggattga agtcgtggaa taatttcaaa
     5821 gtaatgagtt gaaaaaaacg taaaaagaaa aaatcaggaa gagactttaa aaagtttttt
     5881 cctgattttt atatgtttta ctttaaagaa tgcaacaaaa gtttatgaaa gatggacacc
     5941 tttgtcaacg tagataatat caccgatgat tccgctggaa agtgggctga ttaagaaagc
     6001 acaagcatta ccgacttctt cgatcgtcac accttgctga tcaggcgtac gagattcaga
     6061 taactggatc agtttttgat agtctttaac acctgtgaca gctaatgttt tgattgcccc
     6121 agctgagatt ccattgaccc gaattccttt aggcgagaac tcagctgcca aataacggat
     6181 agcagcttca agagaagctt tcgcaatacc catcatgtta taattcggga ttgcgcgttc
     6241 tgaacctaga taagtcatgc taacgatccc gctgtttggt gcaagaaacg gttgtgcgta
     6301 ttttgataca gcaattaaag agtagctgct gatatcttga gctaattgat agccgtctct
     6361 ggaaatatca gacacatttc cggacaattc ttctttgttg gcgtaagcaa ctgcatggac
     6421 aaggccgtgg atctccccag catattcacc gatggcattc attgcttttt cgatgctttc
     6481 gtcgctagaa acatcacatt ctacagtgaa tgcttcttcg ccgaccaatt tgactaatga
     6541 ttttttcatt cgttcatttt ggtaagtata gataatttct gccccttgtt tcaacattgc
     6601 ttcagcacaa ccccaagcaa tgcttttttt gttagcgacg cccataatga cgattttttt
     6661 tccttctaga aatgacataa tgactctcct ttgtttctga taaaaatttg atagtcgtaa
     6721 aaaaatagag aataatagct aaaataactt cttgatttct taattattag tcaaaatgtt
     6781 ttgattgtca aactattttt tcttaaatta aaaaaagatt gctaaatatt taggaatatg
     6841 atactttgat agtcaaagta atgaaaatgg caattgcctg aaagaaggag tttaattatg
     6901 tcttacgtat tatctgctac tgaagtaatg gaattgattc ctaatcgtta tcctatttgt
     6961 tatattgatt atgtagatac tttagaacca ggaaaaaaga tcgttgcgac aaaaaatgta
     7021 acaatcaatg aagatttttt ccaaggtcac tttcctgaca atccagtgat gccgggtgcg
     7081 ttgattctag aaacactggc acaagcaggt tcgatactta tcctaaaatc agaagagttt
     7141 ctaggaaaaa gagcttatat cggtgggatc aataaggcca aattccgtca aaaagttgtt
     7201 ccaggagatg tgctgaaatg tcattttgaa atcaccaaaa tgaagggatc agtcggtaca
     7261 gcgttatctg cagcatatgt agatgataaa aaagtctgtg agtgcgagtt cacgttcatc
     7321 gtcaaccaaa atgcttgact ataaaacctg atatagcaaa acaaaaggaa gcttacttgc
     7381 tttttatgta aaaagaagac gcctgaatcc tagcatacgt tgtcatctat gcaggattca
     7441 gacgttattt ttttattttt gttttgcttc ttgcagtata ttgattttat cgatttttac
     7501 ttcttctttt ggtttgtctg aactatctgt ttcgatattt gcaatagcat ccacgacatc
     7561 cattccttca atcacttggc cgaagacagt ataatggcca tctagtgaag gataaccgcc
     7621 gtttttataa gcgtcgatga ttgcttgagg atagtcgtct tttaaaagac catcatgcat
     7681 atcatctgta ttttgaacga taaagaactg gctgccgtta ctgttaggat cttgtgagcg
     7741 agccatagat aacgcacctc ttatattata aaggtggttg ttgatctctg tttcaaatcc
     7801 ttctccccaa atgctttccc ctccagtgcc atcgccttta ggatcgccac cttggatcat
     7861 gaaatctttg atgacgcgat ggaaagtcag tccgttgtag taaccgtctt ttgcatgtgt
     7921 cataaagttt tcaaccgctt ttggtgcgtg ttcgggaaat aatttgattt tgattgtgcc
     7981 tttattcgtc accatttcga ccagatcttc attttcggcg acatctttcg tcaattgtgg
     8041 taattccaat gcgttcaaat cgacgctact ggcagtcgtg ctttccgcag tagatgtact
     8101 ttttgaactt tctgtagacg aactagaaga agtcgtgttg tttgcagaac aaccagcagc
     8161 aaacagcaat gctgctgcta aactaatact taaaataact ttatttttct tcataactgt
     8221 tcctttccaa tttactattt tgttatcttt aatgataaca aaatagaggg aaaataccta
     8281 cttaaattat tggaatttat catttatttt aaaagaaaaa gaaaaggtgt agaccattta
     8341 ctttgtgttt gctataatgt aagtggatac aaaaacgaaa agatgcagga ggaaatggta
     8401 atatgggaaa attaggaatc tcgatttatc cagaacggtc aacatttgaa aaggacaaag
     8461 cgtacttgga tttagctcat aagtatgggt ataaacgggt ttttaccagt ttgctgcaga
     8521 tcaatgatga taaagaaaaa gttctttcag aatttaaaga agtagttgat tacgcgaata
     8581 gcctaggcat ggaagtaatg gttgatatca atccagcgtt atttgaacag ttggagattt
     8641 cttacgatga cttatctttt ttccataaga tgggtgccta cggggtccgc ttagatatcg
     8701 gattcacagg agcagaagaa gcaaaaatga cgcgcaatcc ttttggtatc aaaatcgaga
     8761 tcaatatgag ttcgggcacg aattacgttg acaacatcat gagttattcg ccaaacacgg
     8821 ataatttatt aggttctcat aatttttatc ctcatcgata ctctggttta ggatacgaac
     8881 actttgtttt ttgttcagaa aaattcagaa aatataattt gaatacgatg gcattcgtca
     8941 attcgcaatc tgctgagttt ggcccttggc ctacgcaaga tggcttgtgc acgctggaag
     9001 accaccgaga tcttgaaatt gcgacacaag tgaagcattt aatccttaca ggattgattg
     9061 atgatatttc tattggaaat gcgtacgcaa gtgaagaaga attgaaagaa atggcagaag
     9121 catttaacgc ggattatcca acattgaaag tagatacgga agaaggtatt acagaaaacg
     9181 aacgaatctg cttgtttgat aaccttcata gttatcgagg ggatcgctca gaatatatcc
     9241 ttcgttcaac gatgactcgt gtatactaca aagataaaga tttcccgcct cataatacgc
     9301 gagatatgca tcatggggat gtactgattg acaatgaagg gtacggtcaa tacaaaggag
     9361 aaacacaaat cgccttgaag gatatgaaaa acgacggacg tgtcaatgtt gtaggaagaa
     9421 tctccgatga cgaattattc ctccttgact ttttgaaacc atggtcaagc tttaaattaa
     9481 ttgaaaataa aaaatagata attagttatt gcagaaataa tccgctagaa atagccagtt
     9541 atttctgctt ttttattttg tttttttata g
//
LOCUS       DBGZHO010000086         8880 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.089, whole genome shotgun sequence.
ACCESSION   DBGZHO010000086 DBGZHO010000000
VERSION     DBGZHO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.089"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(25..318)
                     /locus_tag="ACN3HL_002566"
     CDS             complement(25..318)
                     /locus_tag="ACN3HL_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HHC8007370.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(346..1011)
                     /locus_tag="ACN3HL_002567"
     CDS             complement(346..1011)
                     /locus_tag="ACN3HL_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HHC8007371.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1151..1783)
                     /locus_tag="ACN3HL_002568"
     CDS             complement(1151..1783)
                     /locus_tag="ACN3HL_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HHC8007372.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1790..2857)
                     /gene="liaS"
                     /locus_tag="ACN3HL_002569"
     CDS             complement(1790..2857)
                     /gene="liaS"
                     /locus_tag="ACN3HL_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HHC8007373.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2854..3585)
                     /gene="liaF"
                     /locus_tag="ACN3HL_002570"
     CDS             complement(2854..3585)
                     /gene="liaF"
                     /locus_tag="ACN3HL_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HHC8007374.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACN3HL_002571"
     CDS             complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACN3HL_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HHC8007375.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACN3HL_002572"
     CDS             complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACN3HL_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HHC8007376.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5748..6917
                     /locus_tag="ACN3HL_002573"
     CDS             5748..6917
                     /locus_tag="ACN3HL_002573"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HHC8007377.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7184..8818)
                     /locus_tag="ACN3HL_002574"
     CDS             complement(7184..8818)
                     /locus_tag="ACN3HL_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HHC8007378.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2816 a         1698 c         1321 g         3045 t
ORIGIN      
        1 aaaattgtgt caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag
       61 gttgggatca taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc
      121 gataaaaaaa agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac
      181 tgacattcca atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa
      241 acgtattccg taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg
      301 cgttaccgtt aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt
      361 atcgtctaga atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg
      421 aacatattca tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac
      481 tactgttaag tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt
      541 aggattggag actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa
      601 aatattcttt gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac
      661 gacgcgatca gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc
      721 taaaatattt ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat
      781 atcttctcca atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt
      841 catttcatcc tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac
      901 ccgatcttca ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca
      961 gatacttccg ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct
     1021 cctttagtat cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca
     1081 ttattgtaaa aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt
     1141 atcatcgttt ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt
     1201 cttccacttc tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa
     1261 taaacaattc gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt
     1321 cattttcccg attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt
     1381 ccatcatttt tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta
     1441 tagcatcagc aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt
     1501 caatggcagg ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt
     1561 ctggccaatc ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta
     1621 agtccattaa aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat
     1681 tttcagcttc tccaattact tcaatgtctt cttgaataga taaataagaa gagacgccta
     1741 agcgcaccat ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct
     1801 tcatcaaagg gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta
     1861 ctgttccacc aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt
     1921 tcgtttcatt catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt
     1981 ctattttgtg caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata
     2041 acaattcttg aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt
     2101 ctacatccca tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgctcga
     2161 taccttgctt taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac
     2221 gcatctcaga ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca
     2281 tttctggtgt ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg
     2341 caaacaattg ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt
     2401 ctaaaatttc ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta
     2461 attcactaga tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt
     2521 tgatgtataa atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat
     2581 tgccagaaga aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa
     2641 gtgataataa tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga
     2701 taagcggaac atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc
     2761 tggcataaaa ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat
     2821 aaacagctag catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc
     2881 aatcaaggta ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta
     2941 gattttgatt tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac
     3001 taatgtcgca tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc
     3061 tatccctttt cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc
     3121 tatgatagta tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt
     3181 tccaatacgt tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa
     3241 ttgctctgtt tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc
     3301 tatccctgaa atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat
     3361 ccataaagca ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg
     3421 aaaattttga aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc
     3481 gaatatcact aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag
     3541 cagtagtgct tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc
     3601 ctgacacatt ctcatttcat catacctatt tttttaactg ttggctatag gactttagat
     3661 gtaagatcgt ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc
     3721 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
     3781 aactaacata tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat
     3841 caatgcttgc gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc
     3901 gcttccgaca atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt
     3961 tttaccaatt gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg
     4021 aatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga
     4081 ttcatattca gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat
     4141 gatttctccg cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc
     4201 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
     4261 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc
     4321 aaatgtaaat gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt
     4381 tacatatttt tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc
     4441 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
     4501 gattgcctct tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa
     4561 attatatggt gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa
     4621 tgcgtataaa acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa
     4681 gacttgtgca atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
     4741 tagagttaaa acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg
     4801 catgaccgta ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt
     4861 gtaataatca tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc
     4921 tttagatgca ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc
     4981 atcattcact aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc
     5041 agcaatctga tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt
     5101 tggctcagaa gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg
     5161 cgctaactga taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt
     5221 gaaaacaatc ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt
     5281 agaagagcca ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt
     5341 caacccgcta tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa
     5401 tgtaagagca atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt
     5461 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact
     5521 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat
     5581 tcattataca tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat
     5641 gtaagtagta aatccattac tataagatta aaataaatgt tatcaagata caagctattt
     5701 tagctttatt ctttctgtaa aaaagaaagg agactaaata aactattatg aaaaaaggaa
     5761 aacatgctaa aaaaagaaaa tattcatttt taatgatcgt tgtcgtgttg tttagcctta
     5821 gtgcgttctc tacaggaact attcttggat ggcaatttta caataatgaa cactctcaga
     5881 tagttgccca tgctcaatca gctcaaaaaa agttgatact gactaccaat gaacaacagc
     5941 tcgttgaaaa aatcgatcaa ctattaagaa aaaatgatta tattggctca atttacgtaa
     6001 agaaaaataa tcgcatcatc atggaaaaag gctatggcta tgcgaataaa ctcacgcaac
     6061 aaccaaatga tccttctctt tattatcaga ttggttcggt tcaaaaagca ttgactactc
     6121 ttttgatttt aaaacaagtc gagcgtgggc acctttcttt agatactaag ctggctcaat
     6181 tctatccaca aattgctggc agccagcaaa ttactatccg tgacttgctg tatatgcgct
     6241 caggcttgca ccgaactgct tctccaacca taccgatgac tgatgaagaa gtcgttcaat
     6301 ttgcgattca gcacttaaaa tttacagatt atcagacctc tcattatgat tcattgaact
     6361 ttaccatatt gactggaatt ttgatcaaat taacaaatca accgtatgaa aaattattga
     6421 ccgatgatat catcgaacct ttaggattac agcatacaaa attttatgac caagtcaaaa
     6481 attcatccaa tcatgcacta tcctatcaaa tgtctaaaga ggatgattac tttaaaccac
     6541 tgacagaatc tgaaacagag atccataacg aattagggac tggtaatatc agtatgtccg
     6601 tctatgattt aaatacgctg tttacacaag ttttatctgg aaaactagtt tccaaagact
     6661 tactcttctc attatggcgt gaaaatgcga atggacatcc atatagtggt ggggtatata
     6721 gcggagataa ttatatcctg tcgcaaggaa atatcgactc ttttgataca tctgctatat
     6781 ttagcaaaga ttcacaggat gctatcatca tggaaagcaa tataaaagct gacaaaacta
     6841 tcaaactgcc tactgctgat ctaagaaacc aaatctatga cctgatggaa ggaactacta
     6901 agttggcaaa tagctgatat gatgaaaaga tagcaaatac tacttctttg aatagcattt
     6961 gcttaaaaaa agtactcgac taaacgtagg aaagagtgtg ggacaaatct aaaaatcaat
     7021 ttttgctaca gactttaatt ccaaataaac agaacagaaa gaggtgttct tctttctgtt
     7081 ctgtccaaat tattctaaga tttctcttta ccaacattat ttgacaaagg gcctattaaa
     7141 tctaaaatag tatctttaga ttgctaaaat atgtgctagc aaatcattca tggcttgttc
     7201 ttatttttaa ttttatgcaa taaaaaagaa gaacaattag cgtgattata gaaataaata
     7261 atgagatttt agaaaaaaat gtgtatgaat acctgattgt tactttattt attccacttt
     7321 cactttttac tgtaacaaaa ggacctcctt gttttagtac tgtagcattt tttgaattaa
     7381 cagtaaccgt taatccttta taccggaata caggtaaaac tattgttttg ccttttgaag
     7441 atttaaacgt aaatgtaatt tcatctttat ttggagaaaa gctactataa ataacttgac
     7501 catcttctgt aacttgatgg tttttcaaaa gcaattgatc ttttttatag cctataggta
     7561 cataatcaaa attctcaaat tcttcaagtt tattttccat ttgttcatta gaataagttc
     7621 cttgaaaatt catttctttc accatgttaa ctactgatga ataatttaaa attgaaatag
     7681 ctaatattaa taatagtata aaatttcttc tccttgtata agaaaatttt tccaactgtg
     7741 gagaaataaa tagagatact gaaaaagata tgaacaatgt tgaaaatatc ataaaacgcc
     7801 aaggagcttg aataatattt aaaggagtat tttgtaaggc aaaccatgga aatatttttg
     7861 tacaaagtag aatagatatt atacccatta tataagtgat tttagataag attcctaatt
     7921 ttttaaagtt aaatgttagt ataattaaac aaataagcaa agttaagcca ataccaaatg
     7981 atagtaattc tgaatctata cttccaatca aaaactcttt acccagataa attgctcttt
     8041 tttgtaatat atccacataa ggtctattca gatcttgata caatgtctgc tcaatcatag
     8101 gacctataaa cgctagtgaa agaagtaaag taactatagc agcttttatt aatttaataa
     8161 ttaagaagat ttctattttc tttttccgat aaaattgaat aattaaagca attataatca
     8221 ttaccatagt catagctaca gaaagaacat gagtgtaaat taataaagtc atgctaatcg
     8281 ccaacataac ccaagattct ttttttgagt cgtaaagctt tataaacccg agtaaaataa
     8341 gaggaagtat tgacattgcg agtaattccc ccattgcccc tcgaagaaat atttctacac
     8401 tcctaaaaga agatgttgta tatataatag cgaaaaagga gctagtaaca tgttttttgg
     8461 taatttcata cattacataa tgacatataa atagagtaat gagcgtaaca atataaagaa
     8521 aaaggttata gcctattgct aaattagtaa acttgatcaa taaaaataaa ggatatagag
     8581 ttaaccatgg gtaaaaatta tttacttgca tgccatatga tctaaacgtt tcaaaattaa
     8641 taggggagct aaaaatagat tctaaactta acgcacgatt aatgtgaaat gccgtatcat
     8701 aaaagccaaa tatttccatg tttttaaatg ctggaaataa atataataaa ctaacaaatg
     8761 cataaactat aaatattttt acagaaaaaa tttttttcaa attcatatac cacctcatgt
     8821 ttttttatat tacatatagt atcatttatt tttttaaaac actagattag tcactatata
//
LOCUS       DBGZHO010000087         8807 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.090, whole genome shotgun sequence.
ACCESSION   DBGZHO010000087 DBGZHO010000000
VERSION     DBGZHO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.090"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..242
                     /locus_tag="ACN3HL_002575"
     CDS             <1..242
                     /locus_tag="ACN3HL_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HHC8007379.1"
                     /translation="KLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRH
                     SLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            303..803
                     /locus_tag="ACN3HL_002576"
     CDS             303..803
                     /locus_tag="ACN3HL_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HHC8007380.1"
                     /translation="MEMKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEE
                     YAIHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENK
                     EDIHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHG
                     VFEYCQ"
     gene            859..1497
                     /locus_tag="ACN3HL_002577"
     CDS             859..1497
                     /locus_tag="ACN3HL_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6037 family protein"
                     /protein_id="HHC8007381.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            1569..1964
                     /locus_tag="ACN3HL_002578"
     CDS             1569..1964
                     /locus_tag="ACN3HL_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8007382.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            1948..4401
                     /locus_tag="ACN3HL_002579"
     CDS             1948..4401
                     /locus_tag="ACN3HL_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8007383.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            4398..6425
                     /locus_tag="ACN3HL_002580"
     CDS             4398..6425
                     /locus_tag="ACN3HL_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HHC8007384.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            6422..7444
                     /locus_tag="ACN3HL_002581"
     CDS             6422..7444
                     /locus_tag="ACN3HL_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HHC8007385.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            7461..8390
                     /locus_tag="ACN3HL_002582"
     CDS             7461..8390
                     /locus_tag="ACN3HL_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HHC8007386.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            8704..8751
                     /locus_tag="ACN3HL_002583"
                     /pseudo
     CDS             8704..8751
                     /locus_tag="ACN3HL_002583"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2979 a         1480 c         1759 g         2589 t
ORIGIN      
        1 ctaaattata tagtaggata caacaattaa ttgaaaaaga aattcaacct actgaacttg
       61 ctgatatagt gaagacaacg ataaggtcat caaatggaat gattagctct cttaatgaag
      121 caagaaatag gcattcactt gcacacccta atacaaatat tattggaaag agagaagcaa
      181 aactaataat aggtatttca agtacagtta cagattatat tagcggatac cttgataagt
      241 agcgtcatta actgattgct acttttttta tgactatttt tataaaaagg atgtgataag
      301 aattggaaat gaaagtctat gtggcaaatt taggacggta taatgaaggt gaattagtcg
      361 gagcatggtt tactccacca attgatgagg aagaaatggc agaaagaatc ggtttaaatg
      421 aggactacga agaatatgca atacatgatt ttgagcttcc ttttgatgtg gacgaataca
      481 cgccgattag tgaaatcaac cgtctatgtg aagccattca agaaatcgaa ggtacaccta
      541 tttataatga actcaaagaa attcaaggca tgtggtttag tagcttggaa gaattactgg
      601 aaaacaaaga ggatattcat tgttatagtg attgtgattc gatggaagat gtcgcccgtt
      661 attacgtgga agaaacagga cagcttggtg aagtcccttc caatttacaa aattatattg
      721 actaccaatc tttgggacgt gatatggaaa tagagggtaa ttacctagtt acctctcatg
      781 gggtatttga atattgtcag taagtttaac aatccgtgtt ataattaaat taataaatag
      841 cacggagagg tataaattat ggtaaatgta tttgaaaatc ttaaactatt aaaactagac
      901 atgaaagata aaggctgggt gatagattcc ttttactttc gttacaaaca gcaaaattat
      961 attgtacttg ttaagctatt tgaaaaagag gaaaaagttc cagaatatgc tctgttaaaa
     1021 ctagaatttt taaaggaaaa cgatttttca gatatgctag ctgtctatgc taattcggta
     1081 aaattatata cagacacgaa aacaataaga gaatattttg gtatcgaata cagtagtaac
     1141 ttgggagatg ttttatttca atttagccaa actcttgctc gatttattcc gacagaagtt
     1201 agtgagaaga aaaatgaaga ccaaaaagaa gccatgtgtt tctcattaag tcaaagtgat
     1261 tcagaagatc ccagaaaaaa atattgtttt tcagttagaa gaaatccttt aaagggaaat
     1321 ggtgagctgg gaaaacgaag tccttttaat gacaataaaa cgagattgta tagacccagc
     1381 ttatatgaac gattagggtc agataccaat ttaagtttca gatattcaat gaatccagat
     1441 gatgaagaaa ctgatgaagg tattattgca aaatggacaa aaaataaaat tgaatagtta
     1501 aagcattgaa agagcaatca cctattttga ttgttctttt tctattttta cggaaaggac
     1561 gtgaagacat gaaaaaaata agaagttaca ccagtatttg gtcagtagaa aaagtgattt
     1621 atgcgattaa tgatttacaa ctccctttcc caattacctt tacgcaaatg acatggttta
     1681 tcgtttcttt gtttgtcgtc atactctttg gcagtttacc accactttct ctgattgacg
     1741 gagcactact caaatactta gggattccca ttgttctcac tgggttcatg tgccaaaaga
     1801 cctttgacgg aaagaaaccc tatggatttc taaagtctat cattacctat gctctacgcc
     1861 ctaaagtaac ctacgctggc aaacaaatac gattaaaaaa agaaacaatg aatgaatcga
     1921 ttacgattgt aaggagtgaa caactagatg gcatatccga ttaaatatat ggaagataat
     1981 ctcgtattta atcatgatgg cgaagtattc gcttattatg aattaattcc ctataattac
     2041 agttttttaa gttccgatga aaaaattcaa gttcatgata atttctgtca attgattgcc
     2101 caaaatcgtg atggcaagat tcatgctctg caactagcaa ccgaatcaag tattcgagcc
     2161 acacaggaac aatcgaaaaa agaaatcact ggacgattaa aagagatagc ttacgaaaaa
     2221 atagatgaac agaccgaagc gttaatttct atgattggtg acaatcaagt agactatcgc
     2281 ttttttattg gttttaaact ctacctcaat gaacaggaag tatccgtaaa aaatgttggg
     2341 aaagaaattc aaaaagcatt tgcggaattc tttcatggtg tgaatcacaa attaatgggc
     2401 gattttgttt ctatgcctat ggcggaaatc gaacgctttt ctaagatgga acagttgtta
     2461 gaaagtaaat tatccagacg ctttcagatt cgtaaattgg agaaagatga ttttggttat
     2521 attattgaac atctttacgg gcaaacaggt gtcccttttg atgactacga ctaccattta
     2581 ccgaaacgat acgaagataa aaaagtgttg gtaaagaaat acgatattct caaacccact
     2641 cgctgtttaa tcgaagaaaa tcaacgctat ttacggattg aacaggaaga taccactact
     2701 tatgtggcgt attttacaat taatagtatt gttggtgaat tggatttccc taatagtgaa
     2761 attttttatt accagcaaca gcagtttact ttccccgttg ataccagtat gaatgttgaa
     2821 attgtcgcca ataaaaaagc cttatctacc gttcgcaata aaaagaaaga actgaaagat
     2881 ttagatagcc acgcatggga aagcgacaac gaaaccagta ctaatgtggt ggacgcttta
     2941 gaatctgtcg atgaattaga aagtaattta gaccaaacca aagaatctat gtacaaacta
     3001 agctatgtgg tacgggtatc agcaaagaat ttggacgagc tgaaacaacg ttgtgatgaa
     3061 gtaaaagatt tttatgatga tctgtctatc aaattagtac gaccttttgg cgatatgcta
     3121 ggcttgcata atgaatttat tccctcaagc aagcgatata tcaatgacta tattcaatat
     3181 gtcacgtcgg attttttggc tggtcttggt ttcggtgcta cacaaatgat tggtgaaaat
     3241 tctggtattt acgtcggtta caatctcgat acaggcagaa atatttatct ccaacctagc
     3301 cttgcaagtc aaggaattaa aggctctgta acaaatgcat tagcgtccgc ttttattggt
     3361 tcattaggtg gcggaaaatc attctctaac aatatgctgg tctattattc agtactcttt
     3421 ggcggacagg caaccattgt tgacccaaaa gctgaacgtg gtgaatggaa agaaacctta
     3481 cctgatattg cccatgaaat caatattgtt aatctcacga gtgagaacga caataaaggg
     3541 ttacttgacc cttatgtgat tttaaaactc ccgaaagatt cagaaagcct tgccattgat
     3601 attctcacgt tcttaacagg tatttccagc cgagatagcg agaagtttcc tgtcctgcgt
     3661 aaagctattc ggagtgtaac tcaaagcaaa caacgagggt tgttattggt gattgatgaa
     3721 ttgcgaaaag aagatacgcc catcagcaat agtattgctg accatatcga aagctttgtc
     3781 gattatgatt ttgcccatct gttattcagt gatggcagtg tcacccaatc cattagcttg
     3841 gaaaaacaac tcaatattat tcaagtggca gatttggtct tacccgattc caatagctct
     3901 tttgaagaat acactaccat ggaattatta agtgtggcaa tgctgattgt cattagtacc
     3961 tttgctttag actttatcca ctctgaccgt tccattttta aaattgttga ccttgatgag
     4021 gcttggagtt ttttacaagt ggcacaagga aaagctctat ctatgcgatt ggttcgagca
     4081 ggacgtgcca tgaatgcagg ggtctatttc gttactcaaa acgcggacga tttactagat
     4141 gaaaagatga agaataatat tggcttgaaa tttgcctttc gttccactga cctagtggaa
     4201 atcaaaaaga ccttagaatt ttttggtgtg gacaaggaag atgaaaacaa tcagaaacgc
     4261 ttacgtgaat tagaaaatgg acaatgttta gtttcagaca tctatggtcg tgtaggggtt
     4321 atgcagtttc acccgatttt tgaagagttg cttcatgcct ttgataccag accgcctgtg
     4381 cgaaatgagg tggaagaatg acacaaaaac aaaagaaatt tcttcactat agttggataa
     4441 cgctcctttg tgtgggcgtt attttacttt tattaggcac gctgggcaat gcagtacaag
     4501 cgacaggctt agttgatgaa accattgata caagcaatga atactccaag tatggtttga
     4561 atcaatatca gcttgattat tatgtggaca atagctgggg ctggcttcca tggaattgga
     4621 gtgatggcat aggacaatcg gtgatgtatg gattgtatgc cattactaat tttatttgga
     4681 caatttctct ttatctatcg aacgccacag gttatttggt gaaagaagcc tatgccttag
     4741 atttcattag tcaaacatcc caagcaattg gcgaaaacat gcagacgatt gcaggcatta
     4801 caccgaatgg cttttccagt tcagggtttt atgtcggttt cctccttctt tttattctca
     4861 ttgttggaat ctatgttgcc tatacaggat tggttaagcg agaaacgacg aaagtgatac
     4921 gagctgtttt aaactttgtc gtggtgttta ttctatcggc ttcctttatt gcgtatgcac
     4981 ccgattatat tgcgaaaatc aatgattttt ccaaagatgt cagtaccgcc agtctgaata
     5041 ttgggacaaa aattgttctt cctaacacgg atagtcaagg gaaagacagt gtggacatga
     5101 tacgtgacag cttattctct gttcaagtaa agcaaccatg gctattgctt caatatggct
     5161 ccactgatgt agaagcgtta ggggaagaac gtgtggaaag tttattgtct accagtccag
     5221 atacaaacaa tggtgaagat agagaaaatg tagtgattga agaaattgaa gatcatgaca
     5281 atacctattt aaccctaccg aagacgattt ccagattagg aacagtcttc tttttgtttg
     5341 tattcaatat tggtatctcg atttttgttt tccttctaac aggaatcatg attttttcgc
     5401 aagtgctatt tattattttc gctatgtttt tgccaatcag tttcctatta agtatgttgc
     5461 cgagttttga tggcatgggc aggcatgcca ttaccaagtt atttaatgtg attatgacaa
     5521 gggctggtat taccttgatt attaccgttg cctttagtat ttccactatg ctttattcgc
     5581 tgtcagcaag ttctcccttt ttcatgatta tgtttttaca aattgtgacc tttgcaggga
     5641 tttattttaa actgggcgat ttaatgagcc tattcacttt acaaagcaac gactctcaaa
     5701 acatgggcag acaagtgttt cgcagacctc gtcaaatgat gaatcgacaa accagaagat
     5761 ttcaacgcag tatgagtaag atttttcgtg gaaaagcagg gtcaacgaag caaaagacaa
     5821 tgacaacaaa gcagaatcaa accaataaag ctaaccatac tcgtcaaaat gaacggacta
     5881 caccaaagaa agaaacagca ctttccaatg tgaaaaagca acaaggcggt atcgggcaac
     5941 gattaggtga aaagacagcc catgtattgg acacgaaaaa tcgtctagtc aataaaagaa
     6001 agcaggcaaa acaacagata caggcgacac caacccatgt caaatatgcc cttcatcaag
     6061 gaaaagagaa tgtcactcat aatgtaacag actttaaaca atctatggca gataccaaag
     6121 ctcaacgcaa acaacagcgt atgaaccagc aggagcaaaa acgaaagaac attgctcaaa
     6181 agcgtttgga gctggataaa gcaaaagaaa aaagacgaaa agaaaaccca tcatctcctg
     6241 ttcagaataa ccagcagcat gttcgcaagc gtcagcaaac cgtcacgcct gttttgtcac
     6301 aaaacactaa acgtgaaaat catcagcgac cattgaaaaa agagcaaaaa caaaagacac
     6361 caccgaagca attcaatcag aggaagctaa ataaaagaac ggataagcga ggacaacaaa
     6421 catgaagcta aaaataacag tgatttgtag tgtggtcttc tctctcttct tttttctctt
     6481 attattccta gtcattttct ttgcagatga tacggacagt ggcgaaaaca acaaggattc
     6541 ttctattcca caaggcggtg tgaccgtttc accagaagtg ttggcacacc gtccgttgat
     6601 tgaaaaatat ggtaaggaat atgggattga agactatgtt tcttatatct tagccattat
     6661 gcaagtggaa tcgggcggta cagcagaaga tgttatgcaa agttccgaat ctttgggttt
     6721 accgcccaac agtttgagta ccgaagagtc catcaaacaa ggggttaaat atttcagtga
     6781 attattaacc agtgcagaac aacaaggagt ggatatagat tctgttatcc aatcttataa
     6841 ttatggcggt ggctttttaa attatgtgag gagtcatggg aaaaaatata cctatgaatt
     6901 agccgaacag ttttctaaag agaagtcggg tggtcaaaaa gcagactatc ccaatcctat
     6961 agccatacct gtgaatggtg gttggcgata taactatgga aatcagtttt atgttcagtt
     7021 ggtttcacaa tacctaaccg acacttcccc aacagaattt gatgatgaaa ccgtgcaagt
     7081 cattatggac gaagccttga aatacgaagg gtttccctat gtctttggag gggcgtcgcc
     7141 taccacctct tttgattgta gtggcttaat acaatgggtg tatgacaaag ctggcatttc
     7201 tctccctcgt gtcgcccaag atcagtatga cgctacgcaa gaaatctcta tggaagaagc
     7261 ccaagcaggc gaccttatct tctttcattc aacctataat gcaggcacat atgtgactca
     7321 tgtggcgata tatttagagg gaaatcgctt ttatcatgca ggcgacccaa tcggttatgg
     7381 cgacttaagc agtcgttatt ggcaagacca tctgattggg gctagacgtg ttattcataa
     7441 ctaagaaagg aatgaatcaa atgattataa aaatcgagcg aaaagaaaag aaggagaaac
     7501 caaagaaatc taaaaaaccg agcaagcaaa gaaaagttcc gatgattaaa gttggcacgc
     7561 ataagaaatt aacctttgtt ttatgggttt tattgattgg tagtgtcgga tttggaatct
     7621 ataaaaattt tactgccatt gacactcata ctgtccgtga aacagaaatc attaaacagc
     7681 agattgtcga taccaaccaa gtagaaagtt ttgtgaaatc ctttgcgaaa gactactttt
     7741 cgtggcaaca atcccaagaa gccattgata aacgaaatga aaaattgacc cattatttga
     7801 cggaagaatt gcaggtatta aatgaagaaa tgattcgtaa ggatattcct actagttcta
     7861 gtgtgaacga tatacaggtg tggcaggttt ctcaagtgaa tgagaacacc tttgaggtac
     7921 tgttttctgt tgaacaagtt attaccgaag acaaagacaa ggaaactata tcgtctagct
     7981 ttcatgtggt tgtccatata gatgaatcag ataatatggt tattatcaaa aatccgacaa
     8041 tgagtaagaa acctcaaaaa tcggactacc aacccaaaca gctagaaagt gaccatacag
     8101 tagatacaga aacgatggac gaaatcacta gctttttaga aacgttcttc cagctctatc
     8161 ctaccgccac agaaaaagaa ttgacttact atgtaagtaa tcatgtgtta cctatgatta
     8221 acaaggaata tgttttcgag gaattggtga atcctatctt taccagaaaa gataaccaag
     8281 taatcgtgaa tgtcgctgtg aaatatttag atcaagaaac aaaggcaacc caaatctcgc
     8341 aatttgagtt gatattagaa aaacaagata attggaagat tgtaaaataa caaatattgg
     8401 tacatgatta cagatacttt gtaatcatgt actctttttg ataaaaaatt ggagattcct
     8461 ttacaaatat gctcttacgt gctattattt aagtgactat ttaaaaggag ttaataaata
     8521 tgcggcaagg tattcttaaa taaactgtca atttgatagc gggaacaaat aattagatgt
     8581 ccttttttag gagggcttag ttttttgtac ccagtttaag aataccttta tcatgtgatt
     8641 ctaaagtatc cagagaatat ctgtatgctt tgtataccta tggttatgca taaaaatccc
     8701 agtgataaaa gtatttatca ctgggatttt tatgcccttt tgggtttttg aatggaggaa
     8761 aatcacatga aaattattaa tattggagtt ttagctcatg ttgatgc
//
LOCUS       DBGZHO010000088         8733 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.091, whole genome shotgun sequence.
ACCESSION   DBGZHO010000088 DBGZHO010000000
VERSION     DBGZHO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.091"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            2..74
                     /locus_tag="ACN3HL_002584"
     tRNA            2..74
                     /locus_tag="ACN3HL_002584"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="ACN3HL_002585"
     tRNA            78..150
                     /locus_tag="ACN3HL_002585"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="ACN3HL_002586"
     tRNA            155..225
                     /locus_tag="ACN3HL_002586"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="ACN3HL_002587"
     tRNA            238..311
                     /locus_tag="ACN3HL_002587"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="ACN3HL_002588"
     tRNA            323..394
                     /locus_tag="ACN3HL_002588"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /gene="metK"
                     /locus_tag="ACN3HL_002589"
     CDS             660..1853
                     /gene="metK"
                     /locus_tag="ACN3HL_002589"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HHC8007387.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="ACN3HL_002590"
     CDS             1983..3455
                     /locus_tag="ACN3HL_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HHC8007388.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="ACN3HL_002591"
     CDS             3538..4326
                     /locus_tag="ACN3HL_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HHC8007389.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="ACN3HL_002592"
     CDS             complement(4393..5061)
                     /locus_tag="ACN3HL_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HHC8007390.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="ACN3HL_002593"
     CDS             5176..6888
                     /locus_tag="ACN3HL_002593"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007391.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="ACN3HL_002594"
     CDS             6891..8663
                     /locus_tag="ACN3HL_002594"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007392.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2623 a         1487 c         1945 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc aga
//
LOCUS       DBGZHO010000089         8611 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.092, whole genome shotgun sequence.
ACCESSION   DBGZHO010000089 DBGZHO010000000
VERSION     DBGZHO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.092"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(140..1093)
                     /gene="menA"
                     /locus_tag="ACN3HL_002595"
     CDS             complement(140..1093)
                     /gene="menA"
                     /locus_tag="ACN3HL_002595"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HHC8007393.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1106..2209)
                     /locus_tag="ACN3HL_002596"
     CDS             complement(1106..2209)
                     /locus_tag="ACN3HL_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HHC8007394.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2299..3234)
                     /gene="pplA"
                     /locus_tag="ACN3HL_002597"
     CDS             complement(2299..3234)
                     /gene="pplA"
                     /locus_tag="ACN3HL_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HHC8007395.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3536..5470
                     /locus_tag="ACN3HL_002598"
     CDS             3536..5470
                     /locus_tag="ACN3HL_002598"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHC8007396.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5927..6343
                     /locus_tag="ACN3HL_002599"
     CDS             5927..6343
                     /locus_tag="ACN3HL_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HHC8007397.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6357..6923
                     /locus_tag="ACN3HL_002600"
     CDS             6357..6923
                     /locus_tag="ACN3HL_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HHC8007398.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6946..7932
                     /locus_tag="ACN3HL_002601"
     CDS             6946..7932
                     /locus_tag="ACN3HL_002601"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HHC8007399.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8087..>8611)
                     /gene="scm"
                     /locus_tag="ACN3HL_002602"
     CDS             complement(8087..>8611)
                     /gene="scm"
                     /locus_tag="ACN3HL_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HHC8007400.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2529 a         1663 c         1750 g         2669 t
ORIGIN      
        1 caacctcctg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
       61 aaaaatataa ggagctattt ttatttggct gttcttatta cttgatgcag ggcagttttt
      121 tcacaacctc ttcatgctgt taaatggctt gcataatgat tgttagtaat agccccaata
      181 cataactggc attgaataag accatatttt tgatggaata gctgaaactg ataggctggg
      241 gtaacgtttg cttgaattga tccaaatgct tcttcacaat tggcaaggtc aagaaggtga
      301 ccaagatcgg ccattcatag ataccgctca acaaccccat taaaatcacg aaatagcaag
      361 catacatcaa tagctggaat aagactgttc ccgcaggacg tccgatataa aaaactagtg
      421 tatagcgatg attttcaata tcacggtcaa gatcccgcaa attattagcc aacatgatat
      481 tggcaatcgt aaacaccaag ggtaaggaag ctaatacgat tgctgctata gcccaaagat
      541 ttcctaccaa atcaaattgt ccagatgaaa agttgactgt cagatcatag acatctgaac
      601 cgaatgtatt gacataaacg accatggcaa aaattccaag gcccatagtc accccactga
      661 aaatttcccc taaaggcatt cgagataaag gaatcggtcc gaatgtatag aatactccaa
      721 taaaacaaca gataaatccc atcaaaagta aaagccaacc cgtattgatc gttagaataa
      781 cgccgataac aaaaacaaat gcaatcatag ctaaaatcat gtttcgaatc aatacaggag
      841 atagatttct gcggccaatg acattttctt catacttata tacttcagaa tgagcctttt
      901 cataatccat gtaattattg atagcggtag tcgctaaatc aaaaactagc attccaataa
      961 aaaataaaaa agtgtttagc caatgtatct catgaaaaaa agcgatagag aataataccc
     1021 ctaccgcaaa aggaaataca ctagccacct ttgttcgtat ttcaactact tctaaaaaga
     1081 tttttagtgt catggttcgt actccttatt ttagttcaga acggtcaccc atcgtgtaat
     1141 gggagtcctc cgataatttg aaggtgtctt tgattggatc ggtcacatat actttatcgt
     1201 cttttgtcac gaagatcgct tccgtcccgt tattcaattc gctttcgacg tattccagtc
     1261 cttttttcac acccattgaa aagactgctg tagacaaccc gtcaccatca attgatttat
     1321 ctgttatgat cgtgacactt gcgatatcat tgtcgaacgg ataacccgtt tttggatcaa
     1381 acaaatgatg gtattttttg ccatctactt ctaaataacg ctcgtaaatt ccagaggtaa
     1441 ctaatgtttt gttccgttct ttaatagaac ctaaaacaga tccgcgagcc atgttcggat
     1501 cttggatgcc gactgtccag tcttggtttt cgcctcttgg gctgtggcct aagacataga
     1561 cattaccgcc caagtcaacg atggcagtgg tcactccttg ttttttcaag actttcacta
     1621 cttcgtccgt aatgtaacct ttggcgattg cacctaaatc gatgatcatt cctttttctt
     1681 ttagataaac agttttttct ttgtcattta gttcgatctt atgataatcc actaatttca
     1741 atgcctgatc gatttcttct tgggaaggtt ttctggcgtc atcaaaaccg attcgccata
     1801 attgtgtgat tgcaccaatc gccatatcga atccgccttg agaatcttgg ctatattcgt
     1861 aggcccgctt gactaacgtg tagacgtcat cagaaacttt tactggtttg atcccagctt
     1921 gctcattcac ttcatcgatc tcagaacctt tttgattgat cgtgatttta tcaccaagtt
     1981 cttttactcg atcgaaggca ggtttcaatg ctgattcttt gccttcatca tacacacgga
     2041 tacgaacgta agtccctaac aagaactgtt catcagaata tggatctttc aatatcttgg
     2101 tagctgctga actttcagtg gttgttttat ttgctgagtt gctgcagcca gttagcacca
     2161 taaaagagat gcccagtgtg attaaggaaa atagtagttt tttccgcatc tttttcctct
     2221 cttcattttg aaaggtgaga cgactgccta atctggctat cgtcccaccc tccaactttt
     2281 attagtatga ttatgtgatt atttttctgt tacgatatta tctacttcga ttgtttgagt
     2341 gtcgcctttt tcagctgcat tcactaattg ttgtgcgtac atgatgaatg aatgtgagct
     2401 gtgtgtagca cctgtaacaa cttctacatt agcaggtgag ccatcttctt cgcccattgc
     2461 tttgacgaat tcgtcgttca gagtagggat gtaagttttt ggttctgtac cgctttttgc
     2521 tttcatattt tcattatatt ctgtatcatc ttgttttgat ttaccgtctt tgtcgatata
     2581 atcaaagttt gattcagtta ctttgccgcc agcaactgtc atttcgaatt gcacacggta
     2641 gccgttagag tagttctttt cttcaagctt gtaagtgccg tctttcaaat cagcaccatt
     2701 gtcgatttcg attgtatctg tgttaccagc ttgagcagct tggatcaatt gttgtgcgta
     2761 gttttggaag ctttcagatg agtgagtagc tccagttacg acttccacac cgcttgcgct
     2821 ttgtgctttt aagaattggt cattcaactc aggaatgtat ttttctgggt ttgtgccaga
     2881 ttttgcttcc atgtttttgt tgtattctgc atcttttgtt tttgattcgc cgttttcatt
     2941 gacgttatca tattttgatt cagtgatttt gccgtctttt acaaccattt caaagactgc
     3001 acggtaacca tttgaataat ttttttcttc taatttatat gtgccgtctt gcaaatctcc
     3061 gccagctaca acttttgcag atgattctgt tgtgcttttt gcagtcgaag attgtgctgt
     3121 agatgattca gaagaagagt ttgagcttcc gttgtcatct gcgccgcaag cgcctaacac
     3181 tagagctgaa aatgctaata cggcaaatcc agttacaaaa cgttttttct tcattttaat
     3241 accccaccat tccatttcta gtccacaatt tttctttgtg attcattata cattctaatc
     3301 tttttagcct ataagtcaac tatttttgat aaataaccca tgtaatattt caaacgtttt
     3361 ctttcagcaa atttcgtgaa aaaacgcttt attttaaaat ttgaaaaaaa tccaaaagga
     3421 gttagacaaa agaacagaac atctatataa tatatggaga ttgtgtaata agtatcaaac
     3481 taaaagaatt atcatatatt cattatatag atagtctata aggagcggat gatcaatggc
     3541 aaagcaaaat attgtcgttg taggagcagg atatgccggt gtttcagcta caaaatactt
     3601 ggcaaagaaa ctgaaaaaag aagatgtagc aattactctg atcgatcgtc attcgtacca
     3661 tactatgatg accgagttgc atgaagtagc tggcggacgt gtagaaccag aagcaatcca
     3721 atacgatctg cagcatttgt ttgctcgtca aaagaatgta caacttgtca cagacactgt
     3781 aatcggtatc gataaagaac gaaaaatcgt caagaccaaa ttaggttcct atccttttga
     3841 tcagctgatc cttggaatgg gcggagagcc gaatgacttt ggtacacctg gtgtcaaagc
     3901 acacggattc accctttggt catttgaaga ttctgtaagg attcgggaac atattgagaa
     3961 gacagtagca aaagctgcat tggaaccaga tgatgaactg cgtaaagcca tgctgacttt
     4021 cgttgtctgt ggttctggat ttaccggtat tgaaatgatt ggggaactga tcgactggaa
     4081 aaatcgccta gccaaagatt ataaattaga tccaaacgaa atcacactga tggtcgtaga
     4141 ggcaatgccg acgatcttga atatgttgga tcgaaatgat gctgcaaaag ctgaacgcta
     4201 tttgcgtaag cacaacgtgg aattattatt gaatgcacca atcgtagaag tggctgctga
     4261 tcatatcaaa ttgaaagacg gacgcaacat tccgactcac acactgattt ggacagctgg
     4321 tgtcaaagga acttctgacg ctgctgactt tggattagaa tcagcacgcg gacagcggtt
     4381 gatcgccaat gaatatatgc aggcaaaagg ctacgaagat aaaaacatct atatcattgg
     4441 tgatttagtc ttttatgaag aattcccagg aacaccgaca ccgcagatcg ttcaagctgc
     4501 tgaacaaaca ggacacacag ccgcagcgaa tatcgtggct tcgatcaaag gcggagaaaa
     4561 gcataaattt aaaggaaact atcaaggatt tatggtttct attggtgcca aatggggggt
     4621 agctaaccta tttgataaga tccatttaag cggattttta gctatcgtaa tgaaacatat
     4681 cgtgaatttg aaatacttct ttgatattcg ttctggttat tatatgttcc aatatttaat
     4741 gcatgagttt ttccatatca aagatgatcg caacgtgact cgaggacatt cttctcgtta
     4801 cggcaatgtc ttatggagtg tgccacttcg tattttctat ggtttagttt ggttcgttga
     4861 agcttccaaa aaaatcattg ggaatggtga agtgttcaaa ccaagtactt ggtttggtga
     4921 aggatcatgg ttcactggaa acagtgtgtt cccttggaca tgggaataca atgtaacaga
     4981 tgttgccagt ggtgcttctg ctgctggtga tgcaaccaca gctgccagcg gagcaggggc
     5041 aagtgccgga gaagcagcga ctcaagctgc acattttggt ttgagttatg catacggtga
     5101 agaaccaatg gctgtgattg agaagtcacc agactggttc acaaagatca tgcaagtgat
     5161 catgccaaac aatgatgtag caatgttctt ccaaaaattc atggtattct ttgaaattgc
     5221 cttggcatta gcattgattg ctggattatt cacatggcta tgcagtgcga caacgattgt
     5281 attggtgatc acgttctgct tatcaggcat gttttactgg gtaaacattt ggttcatttt
     5341 tgttgctttc gcattgatga acggttccgg acgtgcgatt gggttggatc gctgggtaat
     5401 tccatggcta caacgtacac taggtaattg gtggtacggt agaccaagtt cccagtacgg
     5461 caagaaataa atagataaag aacgttattt gaatgcaaga tttcaataga aaggggctga
     5521 gacaaaccgt cacagcctcc tttttatgta aaattaaagg aataagatgc ccgagataag
     5581 cctccatgag caagacacag gtgtcacaac ctctgttaca acctcttgtt ataaacggtg
     5641 ttccagaagt agcttcttcg aaaaataagc cgaaatttca caaaaacttg aaaagtaatt
     5701 ttcgtaaatt ccttcttatt tcttgaagtt gcccacttct gtcacaacct cttgttataa
     5761 acggtgttcc acctgctgct tctcggtaat aagcccaaag aattagaaaa catggaaagc
     5821 tgttttctat tcttcgttct tattactcaa agcaagacac aggtgtcaca acctcttgtt
     5881 tttatgctaa aattgggtga gttaatctgg aaaaaggaga acaaaaatga gccttaaaga
     5941 atttgctgaa aaaagtctgc tcaaaccttg ggatgttttt attattttgc ttttgactgt
     6001 tctttctttt ttaccagtca tgatttttgg tcttcagcaa aacaccgcaa cagcagaaaa
     6061 agaagcggta ctgcgtgtgg atggcacaga aatcaaaaca ttccctttga tggctggaga
     6121 agagagcaac acatatactt acaaagatga acacggagat tataacttga tcgagataga
     6181 tggcgatcga gtacggataa aagaagcaga ttgcgatgac cagatctgcg tacgtcgagg
     6241 ctgggcaacg aaaaatggcg aaaccatcgt ctgtttgcca cataaattag tgatcgaagt
     6301 ccgttcaaca gatggaggtg acgaagacag tctgatttat tagaccttca cacaccatga
     6361 gtaaattaca aaaaatgatt tatatttcgc tacttgttgc acaaggagtg atcattggtt
     6421 tattggaaaa tatgatccct tatccttttt cttttgcgcc tggtgcaaaa ctaggcttag
     6481 ccaatctaat cacgatcgtt gccattttta ccatgaaaaa acaagacagc ttcttactac
     6541 tttggctacg actattcctg actactttgc taggcggaac gatttccaca ttcctttata
     6601 gtatgagtgg tgctttgctt agttattttg gaatgttatt ggtcaagcaa ttaggaccaa
     6661 aacgtgtcag tatcatcgga attagtgcgg ccggcggttt catgcataat gtcggacagc
     6721 ttttgatggc ttctttcatt gcacaatcat ggacagtcat gttgtacttg ccagtccttt
     6781 cagttttagg gattttatca gggattgcaa tcgggatcgc agcgaattat cttttacgac
     6841 atgtgcagac acttcaacga ttccaaaaag attatgagca gggaaccaaa caaaaatgga
     6901 gcccaatgtt taccaaaaaa taatcgtcac acaaggagtt tttttatgaa gctacatcca
     6961 atgtgggaaa actatcctgc tttaagtaaa gaattgacag aaacactaaa acggatggaa
     7021 gaaactgtcc gcctgaaaaa caaacctgtc gaacaagcca tcaaagaaac gatccatgcc
     7081 ggcggaaagc tgttgcgtcc tgcctatcag ctattgttct cacaatttgg accagagcaa
     7141 gatcgagaca aagccatcgc tttggcagct tctatcgaaa tgctccatac ggccacactg
     7201 atccatgatg atatcgttga tgaagcggat ctgcgacgtg gtcagcctaa tatccgtagt
     7261 cagtttggta atgtcgtttc tgtctatgca ggagactatt tatttgtctg ctgttttaaa
     7321 ctattgtctg attactccac ttccttgaaa agtctccaat tgaattctcg cagtatggaa
     7381 aaagtattga atggcgaatt agggcagatg gatgatcgct ataattatga actttctgta
     7441 aaagaatatt tggaaaatat ttcaggtaag acagctgaac tgttccaatt aagttgttct
     7501 gttggcgctt ttgaaagtgg aacaagcgag cgcttcgcaa aaaaagcagg agatatcgga
     7561 ctttctatcg ggatggcctt tcagattatc gatgatattt tagattatac aaaagagagc
     7621 caggaaatcg gcaaacctgt actagaagac atgcgtcaag gggtctattc tttaccgttg
     7681 atctactctt tgcaaaaaaa caaaccaaag ctactacctt atttagagaa gaaagcggca
     7741 atgacagaag aagatgtcga cgccgtacgc aaaatcgttg aacatacagg aggcgtggaa
     7801 gaagctagga agttagcggc ctcttacaca gaaaaggctt tgaaggaaat aaagaaatta
     7861 cctgccacct ctcttcgaac aaaagagaat ctcttttccc ttacccaact gattttggat
     7921 cgcaaagact gaatagggaa aggttcgata cgtaaataaa tttctcagaa ggaaatctac
     7981 gtgttttttg acaaattgaa ttgtagttct tgtatttatg ataaaaagca aaaataaaga
     8041 gcaacgtccg ttagcgacgt tgctcttttt tatcttgaat atttttttac cttttcgatt
     8101 tcttataact cataaaagtg attcttaaac cgattacaag taatataacg cctgcgagtg
     8161 ttatccaatt attcgattga cttccagttt taggaagtgc tctttttgat ttgtttccat
     8221 tgtcattgct tgttttatta gttaagttaa agttcgtcct gttatccgaa cttgtttttg
     8281 agaaggagac acttgcatga cgtgtatcgc ttgtggtaga cgacgtgtct gtactatcgc
     8341 ttgaagttga tgaatctgag ctatcacttg tggtagagga tgtatctgta ctgtcacttg
     8401 aagctgacgt gtccgtgcta tcacttgtag tggtagatga atctgagcta tcacttgtgg
     8461 tagaggtagt atctgtactg tcacttgaag ctgacgtgtc cgtgctatca cttgttgtgg
     8521 tagatgtatc cgtactgtcg cttgaagctg acgtgtccgt gctatcactt gtggtagagg
     8581 tagtatctgt actgtcactt gaagctgatg t
//
LOCUS       DBGZHO010000090         8385 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.093, whole genome shotgun sequence.
ACCESSION   DBGZHO010000090 DBGZHO010000000
VERSION     DBGZHO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.093"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(82..1233)
                     /locus_tag="ACN3HL_002603"
     CDS             complement(82..1233)
                     /locus_tag="ACN3HL_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HHC8007401.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1387..1917)
                     /locus_tag="ACN3HL_002604"
     CDS             complement(1387..1917)
                     /locus_tag="ACN3HL_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HHC8007402.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(2016..2366)
                     /locus_tag="ACN3HL_002605"
     CDS             complement(2016..2366)
                     /locus_tag="ACN3HL_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HHC8007403.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2523..4052)
                     /gene="ahpF"
                     /locus_tag="ACN3HL_002606"
     CDS             complement(2523..4052)
                     /gene="ahpF"
                     /locus_tag="ACN3HL_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HHC8007404.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(4062..4625)
                     /gene="ahpC"
                     /locus_tag="ACN3HL_002607"
     CDS             complement(4062..4625)
                     /gene="ahpC"
                     /locus_tag="ACN3HL_002607"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HHC8007405.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4769..5431)
                     /locus_tag="ACN3HL_002608"
     CDS             complement(4769..5431)
                     /locus_tag="ACN3HL_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007406.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5615..7261
                     /locus_tag="ACN3HL_002609"
     CDS             5615..7261
                     /locus_tag="ACN3HL_002609"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HHC8007407.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7252..8334
                     /gene="uxuA"
                     /locus_tag="ACN3HL_002610"
     CDS             7252..8334
                     /gene="uxuA"
                     /locus_tag="ACN3HL_002610"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HHC8007408.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
BASE COUNT         2758 a         1611 c         1503 g         2513 t
ORIGIN      
        1 gactgtggcg ttatcgtcac agtccttttt tcaaataaac ggttttcacg atgtctcttt
       61 cacaacttct ttttgattta ctcacacttc ataaactttt tttgtaaaat atttgagaac
      121 aagtggagaa ataagtgtac ttaataaaat cacgataact aaaggtgaat agtactgtgg
      181 ttcgatcaat tgactttgct gtccaatttg taaaatgatc aaagccattt ctccacgcga
      241 aatcatacca gcaccgacca tcaatgaact atgttgagaa aaaccggcaa tctgagcacc
      301 aaaataacct ccaagcaatt tggtcaaaat cgctacaagc gtcaatatag aaataaagag
      361 tagttgttca ctaaagtcag aaaaatcaac ttctaatcct acactgacaa aaaatactgg
      421 tataaatact gcatatccta aagcctctac attgtggtat acttcttctt taacctttgt
      481 ctgactgaca gctatcccag caaaaaaagc accaatgaca gagctaagcc caacaagatc
      541 cgctacgtaa gacattccta aacaaataac tagcgatacg atgataatag aagaatttgc
      601 gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc catttgacta ataagaaaat
      661 aaaaacaaaa taaattagct gttcaatcaa aacaagcggt aaagaagcat tgctagaagc
      721 ttcccccgtt agaaaagata ggctgaaact tagaactaaa acgactaaaa tgtcatctac
      781 cacagaagca cccaaaattg ttgatccttc ttttgtattc actacgttta gttcttttaa
      841 tacttctact gaaatactga cagaagttgc cgcaagaata atcccaaaga aaatcgcttc
      901 atttcccgaa acttggaatg ctttgcctgt caaccagcca aaaacaaccg ggaagatgat
      961 cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt ttcaaaagag ataaatcact
     1021 ttccagacca gctaaaaaca ttaataagat cacaccaatc tccgaaaagt catggactag
     1081 aatatcaggt ttgacccaat tcaatccagc ttggcctagc aaaacaccaa caagtaattg
     1141 tccaatcact gctgggatac ctaatctccg cgagatatgt gagccaatcg ttgttgaaat
     1201 caatatcagg cataaaatac caataaattc cattctcatc attcctttgt ataaaatata
     1261 gcccgaactt agcataacat acattattga aaaaatagga aaatatactc acaaaaaaac
     1321 caacaatcca aaagattttt ttggattgtt ggtttttata cggtctattt taataactaa
     1381 aaatgattaa cgtatagtca tttttcttat tctgatgaaa ttgataatct cctggatgcc
     1441 catgaaaatc aaaataaagc cgaatatttg gaatagaagc atcaaacttt tgaatggatt
     1501 gaacaataag acgaatccgc caatcaacaa cagaatacta ctataaacac tccaactttt
     1561 agcttttgta ttcatgctga agaacaactg gaacaagctg ttgatgataa cagctaatcc
     1621 aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa gcatagacga tcagagctaa
     1681 gatcaggaaa aaaagaccac tgaacagacc gatactccaa gaacctgttt tccttttaaa
     1741 acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca agataggcgg tgatcagata
     1801 accgataaaa tgaaaaacag cagaagggtt tagcacaatc gcaatcccag aaataatata
     1861 aacagcagct cttaataagg cgtatttttg aatattttgt ttaatcgtct caaacatata
     1921 agaaaacctc ctttgactta ttttaacgtg aactagtcat tttaccaaat taaatgttac
     1981 aaaatgagcg aaggagaaga atatctctgg aaaaatcaac ttctgaggat cttttccatt
     2041 tttttgcctt ttgctagctc atcgatcatt ttatctaaat aacgaatttc tttcatcaag
     2101 ttatcctcga tgtcttctac tcgtacacca caaacaacac ctgtaatcaa ggaacgtgaa
     2161 ggattgggga caggggcttc cgcaaaaaat tgttcgaaag tcacttgttt ttgtagttga
     2221 tattctagtt ctgtttggga ataacccgtc agccaacaaa tgatttcatc tacttcctct
     2281 tttatacgat cttttctctc cgcttttgct acatacatag gataaacgct tgcaaaactt
     2341 gtcgtaaaaa tacgattttg cgccataatc agtcaccttt ctttttttca aattatttac
     2401 tacttatagt atataagaaa aagagaagaa aaagcgatta ttcaaaaaaa caaaaaggat
     2461 tgtgacaaaa ttcttgtcac catccttttt tccgctctct gactttttac aatcttcata
     2521 gctcaagtgc gcatcagata atcgaatgct cctaaagctg cagtagctcc tgaacccatt
     2581 gaaacaatga tttgtttgta tggactatct gtacaatcac cagctgcgaa aacgccgggg
     2641 atattcgttg cgccattttt ctcggtcact atttcatttc ttggattcat ttcgatcgtt
     2701 ctatctagcc aatccgtatt agggagtaag ccgactagaa tgaatactcc tgaaacagct
     2761 agtgtatgca tctccatcgt acggcgatcg atataggaga gagattctac ctgattcgta
     2821 ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga cattcgcaag agagactagt
     2881 ttatcctgta agatttgatc tgcttttaat tctggtaaga attctagaac atatacatgt
     2941 tttgctaacc cagccaaatc gattgctgct tcaacaccag aattaccacc accgataaca
     3001 gcaatctctt ttcctttaaa taaagggccg tcacagtgtg ggcaataagc aattccttta
     3061 tttttaaact ctttttcgcc tggtacattg atagaacgcc agtgcgcacc tgtcgcgatg
     3121 atggcggttt ttgctttaag tgatataccg ttagctaagc caatattaat aaaatgttgc
     3181 tctttattta aggaaacggc ctgttgattc atcataatgt cgatagggta actacgcaca
     3241 tgactttcta cttgctgcat caattttgga ccttctgtgt aagaggtacc aatcatattt
     3301 tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat cagcgacaag tcctgtacgg
     3361 attcctttac gtgctgcata gatagctgca ctactagctg ctggtccacc gccaatcact
     3421 aatacatcat aaggttcttt ttcaaacaac tcttcttcaa tcaaagggcc agtgattttt
     3481 tcaacaattt gttcgatcgt catgcgtccg ctactaaatt cttctccatt taaaaacaca
     3541 gttggcactg ccatgatttt tttatcatcg atttcttttt ggaacatccc accttcaatc
     3601 atcgtatgag taatatttgg atttaataca gctaatatat tcaatgcctg tacaacgtcg
     3661 gggcaattat gacaagtcaa gctaacataa ctgtcaaaat gcaatgtttg tgttattttt
     3721 ttgattttaa gactcaaaga ttcactgatt ttcggtgccc gtccactaat ttgtaacata
     3781 gccagtaaaa aagaggaaaa ttcatgaccg agggggatac cagcaaaaac gattccactt
     3841 tctttgccaa ctggattgat agaaaaacta ggtgtgcgca tcgaatctct tttttcccaa
     3901 gagattttag gagacatttc tgctatttcc ttcgtaaatt cagctagttt ttgactattt
     3961 tcactattat ccaaactaac agaaaaaaca ataggagatt caatcagtgc taaatattgt
     4021 tcgagatttt gtttagtttc tttgtctaac atatccacca cctaaatctt tccaacaaga
     4081 tcaaaacttg gtttcaatgt ttcgccactt tctttccatt ttgccggaca aacttcacct
     4141 gggtgggtac gtacatattg agcagcgcga atcttatcaa tcagtgcact agcgtcacga
     4201 ccgattccat ctgcattgat ttccatagct tgaacgattc cgtctggatc aataataaat
     4261 gttcctcgct gagctaatcc ttgctcttca tccaaaacat caaaaatacg agaaatctga
     4321 tgagacggat caccgatcat cacgtattcg attttaccga tagcatctga tgtatcatgc
     4381 catgctttgt gagtaaagtg ggtatcggta gagcaagaaa agacttcaac acctaaagat
     4441 ttcaatgtac tgtattgttc ttgtaagtct tctaattcag taggacaaac aaaagtaaaa
     4501 tcagctggat agaagcaaag aatactccag ttccccataa gatctttttc actgacttct
     4561 aaaaattctc cttgatgata agcatgtgca ttaaattctt cgattttttt cccaatcaat
     4621 gacatagtaa aacctccaat aataattatt tatttataat tattgtaatt tagttggagt
     4681 tgcaaagtca atggatattt tgttatttaa taaagattac tcaaaaacga aggttaatta
     4741 taaaaataga agaggtcgca agaaaatgct actgctggaa atactcggga taacgttgag
     4801 taacagtttc ctgttctttc agcatcatgt gtaagtgcaa tcccgtttga aatcgagctt
     4861 cttctggttt tttatcaact aaagccttga gtaaatcata atgttgttcc atgatcgttt
     4921 cccatggaag cccctgaatg gtcactcgta accagcggaa acgttctaaa tgggtattat
     4981 ggtcatctaa ccagttccaa acttcttttc ttcctgcaat ttcgaaacaa gcttcatgaa
     5041 ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat tttgactgct ttttcttgtt
     5101 cttctaaaat cgtttctagc actattcgtg tttgtgtgtc caatttggaa caacattcaa
     5161 tcatgatttg ctcttccaac tgttctcgga caaagcgagc attttctgca gaaacaagat
     5221 taatttttga aacatacgta ccactttgag gtatcgtata cacgagttct tgctgacgta
     5281 gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc aagatgttcc tccagtgcct
     5341 tttcagatat tttccttcca ggttctaagt cagcatagat aatttgttta cgaatcgctt
     5401 gataagcttg agattgcaag ctgcttttca tctttattcc tccaaaatca tttctatgaa
     5461 cgtagtataa cagaagaggt ctgaaaaaca atctggtatg tcacattaac tagtaaattt
     5521 gtataaatag taaaattttg gttgacatag cgatttttat tgcataaaat tcacttgaat
     5581 acaaaaacta atatgttagt ttaggagggg aaaaatgatt gatttaaaca actggaggaa
     5641 ctttatccct gaattatctc aaaaagaagt agaaatacct cattttgacc gtgcatcatt
     5701 aagagaaaat ggacaaaaaa atcctgtctg gatccatttc ggtggcggaa atctttatcg
     5761 aggatttcat gcagaaatcg ctcaacgttt agcggatcta ggcgaattgt ccactggtgt
     5821 cattgtttgt gaaacattcg atgaagaaat aattgaaagg gcttaccaag attttgatga
     5881 tttgattctt gaagtggtca tgccaagcag tggagagttc gtcaaacgta tattagctgc
     5941 gacagctgac agtctgtatt gtcatccaga ttgttctgaa cactttgata agatgattcg
     6001 acactttgaa aatcctagtt tacaattagt tacttttgct attactgaaa aaggttatcg
     6061 attgaaagat acaaataata aatatatagg accgattgca gtcgatataa aaaatggtcc
     6121 aaagaagcca tcacatacaa tgagtattct tgctgcgcta ctttataaac gttttttatc
     6181 tggagcttgg ccgattgcac ttgtctctac agataatttt tcacaaaacg gtagtcaatt
     6241 acgtacttct ttgctaacga tcgcaaaaga atggcaaaag gaaggttatg tacaaaatac
     6301 atttatccaa tacttatcga atgaagaaat tgttgcgttt ccatggacga tgattgatcg
     6361 tatcaccccg aatccttcct tgtcagttag caaaatgttg gcaaaagagg gcttttcaaa
     6421 tatgtcgatt ttccaaaccg caaaaggaaa taatattgct ccatttgtca atacagagga
     6481 catccattat ttaatcatgg aagatcattt tcccaatgga cgtccgaaat tcgaaaaagc
     6541 tggagtattc ttgactgatc gtgcaacggt agataaagca gatacgatga aggtgacgac
     6601 ttgccttaat cctttgcata cgtctttagc tattatgggt tgtttactgg ggtataggag
     6661 catagctgag gagatgaaag atccagattt atcgctgcta gtttctgaaa tcgggtacaa
     6721 tgaaggcctc ccagttgtgg agtctccagg tatcattgat ccaaagatct ttctggaaga
     6781 agtaattact gtgcgctttt ctaatccaaa tattcctgat atgcctcagc gaatcgccac
     6841 ggatacctct caaaaggtgg cgattcgtta tggtgagacg attaaaaaat atatggaaat
     6901 agaagttaaa gacccgcaga cacttgtatt cataccattg actctcgctg cttggcttcg
     6961 ataccttatt ggcattgatg atcaaggaaa accattcatc ccgagtccag acccactatt
     7021 gacagacttt cagcataagc tttccgatat tcaactgggt acgcaagata catcacatat
     7081 tcatgagaaa atggctccta ttttgtcaaa taaagaaatt tttggtgtag atctttacca
     7141 agcagagctt ggcagaaaaa tagaagaaat gttcatcaag atggtagcag gaccgaatgc
     7201 cgtacgaaaa acattacagg attacttaca agaacatgga ggaaatttat catggaaatg
     7261 acttttagat ggtacggatc acaggaagaa aagattacct tagatgaaat cagacagatt
     7321 cctgcggtca aagggattgt aggcacattg atggatatac cagtaggaga ggtatggcct
     7381 agggagagga tcaaagaact aaaagaagaa attgagtctc gtgggttaac actaaaagta
     7441 attgaaagcg tcaatgtgca tgatgccatt aaaattggat taccttcccg tgagcagtat
     7501 atcgaaaact ataagcagac aatccgaaac ttggcagaat atggaataga agtcatctgc
     7561 tataatttta tgcctgtatt tgactgggtg aaatctgacc ttgactaccg cttagaagac
     7621 ggctcatcca cgttagcttt tatatctgat gatattccag atgatccaag agaaatcgtc
     7681 gcgcgcatcg aacattccag caatgaattt gaattgccgg gatgggaacc tgagcgctta
     7741 gctcatatca aatccttgct tgaagcctat gcatcagtag acgaagaaaa acttcgagaa
     7801 aattttgcct attttctcca atcaatcatc ccaacatgtg aagaggtagg ggtcaaaatg
     7861 gctgtacatc cagatgatcc gccatactcg atttttggat tacctcgaat cgtaaagaat
     7921 cgagaagatt tagattggtt gtgccgcata gtagacagcc cttataacgg aatcactctt
     7981 tgtacaggga gtattgcaga agatccagaa aatgatgtat atgggatttt agcagaattt
     8041 tgtcaaagag atcgaatccc atttgcacat gttcgaaata ttaaattttt agctaatcga
     8101 gatttctatg aggcaccgca taaatccgaa tacggttcat tagacatgta ccgcatacta
     8161 aaaacaatgt atgacaacgg atttaacgga tacatccgtc ctgatcatgg aagaatgatc
     8221 tggaatgaga caggaagacc aggatacggc ttatatgatc gagcattagg tgctgtttat
     8281 ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa gtaaagataa ttagtgaaaa
     8341 aaactgtaat tttattatgt aaataagaag gatgttcaaa ttctt
//
LOCUS       DBGZHO010000091         8276 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.094, whole genome shotgun sequence.
ACCESSION   DBGZHO010000091 DBGZHO010000000
VERSION     DBGZHO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.094"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..382
                     /locus_tag="ACN3HL_002611"
     CDS             <1..382
                     /locus_tag="ACN3HL_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HHC8007409.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
     gene            complement(776..1783)
                     /locus_tag="ACN3HL_002612"
     CDS             complement(776..1783)
                     /locus_tag="ACN3HL_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8007410.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2250..3656
                     /gene="lacG"
                     /locus_tag="ACN3HL_002613"
     CDS             2250..3656
                     /gene="lacG"
                     /locus_tag="ACN3HL_002613"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HHC8007411.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3679..4002
                     /locus_tag="ACN3HL_002614"
     CDS             3679..4002
                     /locus_tag="ACN3HL_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HHC8007412.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            4013..5695
                     /locus_tag="ACN3HL_002615"
     CDS             4013..5695
                     /locus_tag="ACN3HL_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HHC8007413.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            5901..6859
                     /locus_tag="ACN3HL_002616"
                     /pseudo
     CDS             5901..6859
                     /locus_tag="ACN3HL_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6878..7105
                     /locus_tag="ACN3HL_002617"
     CDS             6878..7105
                     /locus_tag="ACN3HL_002617"
                     /inference="COORDINATES: protein motif:HMM:NF019322.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HHC8007414.1"
                     /translation="MYQVFEEMGYPIKTVTRKLEVIKADDTISDLLDVEEGDPMFYFH
                     TQGFSLERLPVEYSISKYRGDINYFVFELAQ"
     gene            7320..8072
                     /locus_tag="ACN3HL_002618"
     CDS             7320..8072
                     /locus_tag="ACN3HL_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8007415.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
BASE COUNT         2686 a         1266 c         1684 g         2640 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa gtggtggtgc aacgaatttt gcgatgtcgt
      961 catcattaat acttattact gccatatctt tagggatgtt aatacccaat tcatggcagc
     1021 cctgaagaac gccggcagct atagtgtcag atggtatgaa acatgcctcg ggcatatctt
     1081 catttaactc agctttcatt ttaagagtta attgataccc ttcgtcaaca gtaaatgatc
     1141 cttgggagaa aatatacttt tcattgagta gtccgctctt ttctaaatga tatcggaagg
     1201 catattcacg gctatcaatc tcttctttac ccgtttctag gttaaagaaa tttcctccaa
     1261 taaatccaat ttttgtgaaa ccttcattaa taaagtagtt aattgcttgt ctggccattt
     1321 cgtggaaatc aggttctaca gtatcgaagt gttcaggtaa tgggtttatt cctcggatta
     1381 cccccttata ccctttttga tttaagtagt acaattcctt ttttgtcaat tgtcctattg
     1441 cgataaatcc agtaatatcg tcaggaatgc tttttacacc atcgttttta gagatgaaaa
     1501 tcaaatctag attagctttt ttactataat ttttcaaatc atctttgaca tgttgatagt
     1561 agacatcctt ttttaactgt tcctctgaga tccaaaaaag aatggcaatc ttgtacagag
     1621 tagtcttaat ttttgtcaga tcatatccta aagatttggc tgtaacgatt attttgtttt
     1681 tagtatcaga tgtaatagag agtgactcat cacctttaaa aagtcttgat atagtagccg
     1741 ttgagtaacc agattttttt gcaatatctc taatagtaac cattgttcat cctcctaggg
     1801 atataataat ccttttcttt gttaaagtaa atcgaaactg ctcttttagt aacttaaatt
     1861 actttttcta gcaggaaacg aaactctgat atcagcagag agcctaatcc attaacagag
     1921 aagattgaat cgataatgga tagccacttg gagaatgatt agtaggtggg attgatttta
     1981 gtgggaatca gtccgttttc ttgtttcgtg taaattaaat tagtaaaaag ataaatttat
     2041 tttacaaaaa aacgtttaca aaacggtttt tgaatggtat atttatttta catcaaggga
     2101 tataagtgct tgtatatcgc aataaaatag atattcgagg tcggtttttc gttgtgtaaa
     2161 aaaatttact tatacatgtt aaaattatgc tgaggtgatt tatggattat tggcatattg
     2221 atcaaactaa ttttcaagga gagattaaaa tgaattataa aactttacca gaagacttta
     2281 ttatgggagg agctacggca gcttatcaag cagaaggctc tacaaaagaa ggtggaaaag
     2341 ggcaagtagc gtgggatact ttccttgtag aaaagggacg ctatactgct gatccagcta
     2401 gtgattttta taatcaatat ccagttgatg ctgaattatg caaaaaattt aaaattgata
     2461 gtattaggat gtctattgca tggagccgta tttttccaaa aggctatggg gaagtgaacc
     2521 aaacaggagt ggaatattat cataaggtat ttgctgaatt gaataagcat ggtattattc
     2581 cttttgtaac tcttcatcat tttgataccc ctaaagaact atttgataat ggagattttt
     2641 taaatcgaga aaatgttgaa catttcgtaa actatgcaca gttctgtttc gatgaatttt
     2701 ctgaggttca ttattggagt acatttaatg agatttatcc agttgcttca aatcaatatt
     2761 tgatcggatc gtttcctcca gaagttcaat ttgatataga gaagactgta acttgtttac
     2821 acaacatgat gtatgcgcac gcaaagacag taaacatttt taaagatggt ggatataaag
     2881 gggaaattgg tgttgttcac tcgctagaga caaaatatcc agcaagtgac aaagaagaag
     2941 ataagcatgc tgcgaaatta gatgatgcgt tatcaattaa gttcttatta gatgctactt
     3001 atttagggta ttactcagat gaaacaatgg cacatattaa tgagatttta gcagcaaatg
     3061 ggcaatctgc agatattgat tctaatgatt ttagagagat gaaaaaagca gcaaatcgaa
     3121 atgattttct tggtatcaat aactatggta gccattgggt taaagagtac aaaggagaaa
     3181 gcacacttca ctacaacact accggagaaa aaggtagcca agtctattgc attaaaggga
     3241 ttggcgagag aatcgtgcgt gaggatcttc cgaaaaccga ttgggattgg atcatttatc
     3301 caaaagggtt atatgattta cttgtacgaa tccaagacga atatccaaat tataataaaa
     3361 tatacattac tgaaaacggg ctagggtata aggataattt tgaagatggg attattctag
     3421 atgatgatcg aatcgattat ttacgccagc attttaatgc gatttccgat gctatcaaaa
     3481 tgggagttaa tgtaaagggg tatttcattt ggtcattaat ggatgttttc tcttgggtta
     3541 atggatacac taagcgttat ggactattct atgtagattt cgatacacaa aaaagatatc
     3601 cgaaagagtc tgcatattgg tataaatttg ttagcgaaac aaaaacgata atataaaaat
     3661 agttaggagg gcaaggaaat ggataggaaa gaattgcaat tattaggatt tgaaattgtt
     3721 gcttatgcag gagatgccag aagttcatta ttaacagtgt tgaaggaagt gagagaaggt
     3781 aattttgata atgttgaacg attattagcg gatgctgatg aaaatttaac cttagcgcat
     3841 aactcacaaa cgaaatgttt agctgaagaa gcgtcaggga acgaaatgga agtaggcgta
     3901 atttttattc atgggcaaga ccatttaatg acaacgattc tattaagaga acttatcaat
     3961 gattttgttg aattgtacaa agaaaaattt gctaaagcat aggagaagaa aaatgaatac
     4021 gattattaag caaattgaga agggaaaacc gttttttgaa aaaatctcac gtaatattta
     4081 tttaggggca attcgcgatg gctttttaac tgctatgcca gctattctat tttcaagtat
     4141 ttttattatg attgcggctg ttccagaagt atttaacgtg acgttaccag aggcattctc
     4201 gacgtggctt tggaaagttt atggttattc aatgggatta gttggtcttt tggttgttgc
     4261 tacaacagct cgatgtttag ctaattcaat gaaccgtcaa ttatctgatt caggtaagca
     4321 gattaatgaa gtttctgtta tgttagcgtc aatttgtggt tttgtaatga tggcagctga
     4381 tcaaattgat ggtgggatag ctactgatta tttagggaca aagggattat tagcagcttt
     4441 cgtttctgcg tttgttactg taaatgtgta taaattctgt gttaaaagag atttgacgat
     4501 ccgtatgcca aaagaagttc ccggaacaat cacacagatg tttagagata ttatcccctt
     4561 ttcaattgca gtatttattg ccgttttgat tgatacggga gttcgtcaat tttttggaac
     4621 atcatttgca gcaggtgtaa ttcaattatt gcagccatta tttagtgctg ctgatggata
     4681 tgtcggtatt gcaatcattt ggggagccat ggcaatgttc tggtttgttg gtgttcatgg
     4741 accatcgatt gttgaaccag cgattgctgc aattatttat gcgaacgtag aaactaactt
     4801 tgaattattt aaaaacggtg cacaagcctc aaaagtatta acagttggtc taggaaactt
     4861 tgttggaacg atgggtggta ctggagcgac actagttgtt ccttttctgt tcatgttgtt
     4921 cgctaaatca aaacaattga aagcagttgg taaagcttca tttattccag tttcgtttgc
     4981 ggtaaatgaa ccgttactat ttgctactcc tattattttg aatccgtact ttctaattcc
     5041 atttttatta gcaccaatcg ctaacgtatg gatattcaaa ctttttgtcg atgtcttggg
     5101 gatgaatagc tttatatccg tattgccttg ggcgacgccc gcaccgattg gcttggtttt
     5161 aggaaccggg tttagtgtgt tggcgattgt attagcggta gtattgattg ttgtcgatgc
     5221 gattatttat ttaccttttg ttaaggccta tgattctgaa ttagtagaac aagagttaaa
     5281 aaacattgct gcagaagaag taaaagaaga attggtcgaa gaaatccaag aagttggtgc
     5341 aactgcggca gttatagttg atgaagcaaa agcatcggtt ggtgaaggaa agcgcgtttt
     5401 agtactttgt gctggtgccg gaacgagtgc aatgttggct aatgcattag aagagggcgc
     5461 aaaagagaca ggtgttaatc tttctgctaa agcaggagct tatggttctc attatgatat
     5521 gatgaaaaat tttgatttaa tcgttctagc acctcaagtg aattcctatt tggatgatct
     5581 ccgtaaagat gcagacaaat tagggataaa agtaattgca actaaaggtg cagaatatat
     5641 caatttaaca cgtgatccta aaggagcagt tgattttgta ttgaagcaat tttagagctt
     5701 gcttagatta ataaagcgct agccaactta gctagcgttt tatcttaaac acaatggtaa
     5761 gcgctatctt tttttgctgt ttaaatttcg ggtattcttt ttgaggcgtc gattgtaaaa
     5821 ttaagctaga caactaaaaa gatcatttgt gctacactca aaatagttcc gaccaaagaa
     5881 ttaataagga gtgagtacaa atgacctaca cccatcttac aacagacgaa ctagtaatca
     5941 tagagtctta tttcaatatc gagaaacctg tcgctcttgt cgcacaaagt ttaaatcgct
     6001 ctagacaaac catttataat gtttattcgt ttctcaaaca aggaaaaaag tgctagatta
     6061 ttaccgtcaa tacaaacaaa ataaatctcg ttgtggacga cgttcaaccg ttttatctga
     6121 tgaacaatca acatatgttc aagaaaaggt agctcaaggg tggtcacccg atgtgattat
     6181 cggccgtggc gagtttccaa ttgattgttc tgttcgtaca ctctatcgga tgtttaaaaa
     6241 aggccttttt gacacacagt cgttacctat gaaggggaaa cgtaaaccga ataatcatca
     6301 agaaaagcgt ggaaaacagg cctttcgcag aacgattcat gaacggaaca gtctctatcc
     6361 acacctgact aaagaatttg gtcatctcga aggcgacacc attgtgggag ttaaacacaa
     6421 gagcgctgtt attacattgg ttgagtgttt atccaaggtt attattactt tgaaaccgac
     6481 aggcagacga gccgaagata tcgaaaacag gttaaatgat tggttcaaat ccatgcctaa
     6541 acacttgttt aaatccatga catttgattg tggaaaagaa ttttccaact ggcgatctat
     6601 aagtaactcg aacgatattg ccatcttttt cgcagatcca ggaacacctt cgcaaagagg
     6661 gctaaatgag cactcaaacg gcttgcttag acgagatggc ttacctaaaa caatggactt
     6721 tagggacatg gatgaaacct ttattcaatc cgttgcctcg aaaagaaacc atattccaag
     6781 aaaatcatta aattatcgaa caccattgga agtatttttg agctgcatag ataaagacat
     6841 attgtctagc ttaatttgac aaatcagaaa agaaaaaatg tatcaagttt ttgaagaaat
     6901 gggttatcca attaaaacgg tcaccagaaa actagaagta atcaaagcgg atgatacgat
     6961 cagcgatttg ttagatgtgg aagaaggaga tccaatgttc tatttccata cacagggttt
     7021 ttcgctagaa cgtctgcccg ttgagtattc gatttcgaaa tatcgaggag acattaacta
     7081 ctttgttttt gaacttgcac aataacttca gattaaataa aatgatttat taaagataaa
     7141 agtcgaatga acaaggctgt cactatgaca gtcatgctcg ttcggtttta ttttttagaa
     7201 tagcagcttg caaattctga aaaattttgc tttccttcct gcagaaggct tcttaagaaa
     7261 acttgttcta gcacttttct taagaatttg atagtcttaa aaagaaaaga ggcgatgaaa
     7321 tgttaaaaac ggatcgattc caagcgatca tgtcgttatt agaggttaac ggtacagtac
     7381 gagtcagcga tattatggag aagttttcgg tttcggatat gacagtccga cgtgatttgg
     7441 acgaaatgga gaaacaagga ttattagaac gcgtccatgg cggagcgaaa ttgaaggatt
     7501 tttatcggca tgtggagctt tctcatagag aaaaacagat tatgctgcaa gaagaaaagc
     7561 agcggattgt ggaaaaggcg aatgaaatga tcaatgatgg tgatacgata tttcttggac
     7621 caggaactac aatcgagctc atgtcaaaaa tcattcaagg ggattcactg cggattgtta
     7681 caaactgttt gcctgttttt gaagaattaa ataagcgaaa agggaatcga aaaatctatc
     7741 tattaggtgg cgagatgcgg gaaacgactc aatgctttgt tggtgaaatc acgaataaat
     7801 cgctacagga tatgaatttt cataaagcat ttttcagctg taatgcttta aatgaacaga
     7861 aaattatgac ttcgactttt gaagagggcc aaactcaaca gatcgctctg aataattctg
     7921 ttgaacgctt tttattgatt gatcattcga aaattgggaa aagagatttt tcagtatatt
     7981 ataatctgaa tgatgtaaca gtagttataa cggatgatga tgaacaaaag cactatgaaa
     8041 aaatcgaaaa agaagaaaaa tatgttgtgt aaatgagaaa ctgccaaact ctagataatt
     8101 agaacttggt agttttttgg tagccttgaa tttaagcgaa ttatgttatt tttagggtgc
     8161 atcattacta attcctccga atacttgaat acaccatttg aaaaaagata gtcgattttt
     8221 ttgggatgtt atgtttatgt gaaggaaaaa atagcagtat caatcaccgc tttatt
//
LOCUS       DBGZHO010000092         8229 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.095, whole genome shotgun sequence.
ACCESSION   DBGZHO010000092 DBGZHO010000000
VERSION     DBGZHO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.095"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACN3HL_002619"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACN3HL_002619"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HHC8007416.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACN3HL_002620"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACN3HL_002620"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HHC8007417.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACN3HL_002621"
     CDS             2591..3376
                     /locus_tag="ACN3HL_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8007418.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACN3HL_002622"
     CDS             3389..4240
                     /locus_tag="ACN3HL_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HHC8007419.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACN3HL_002623"
     CDS             complement(4364..4816)
                     /locus_tag="ACN3HL_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007420.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACN3HL_002624"
     CDS             complement(5281..5649)
                     /locus_tag="ACN3HL_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HHC8007421.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACN3HL_002625"
     CDS             5799..6281
                     /locus_tag="ACN3HL_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HHC8007422.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACN3HL_002626"
     CDS             6318..7328
                     /locus_tag="ACN3HL_002626"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HHC8007423.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACN3HL_002627"
     CDS             complement(7443..8156)
                     /locus_tag="ACN3HL_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007424.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2441 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtct
//
LOCUS       DBGZHO010000093         8130 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.096, whole genome shotgun sequence.
ACCESSION   DBGZHO010000093 DBGZHO010000000
VERSION     DBGZHO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.096"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(5..1258)
                     /locus_tag="ACN3HL_002628"
     CDS             complement(5..1258)
                     /locus_tag="ACN3HL_002628"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HHC8007425.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            1374..2723
                     /gene="gdhA"
                     /locus_tag="ACN3HL_002629"
     CDS             1374..2723
                     /gene="gdhA"
                     /locus_tag="ACN3HL_002629"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HHC8007426.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            2835..4181
                     /locus_tag="ACN3HL_002630"
     CDS             2835..4181
                     /locus_tag="ACN3HL_002630"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HHC8007427.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(4489..4875)
                     /locus_tag="ACN3HL_002631"
     CDS             complement(4489..4875)
                     /locus_tag="ACN3HL_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HHC8007428.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(5143..5292)
                     /locus_tag="ACN3HL_002632"
     CDS             complement(5143..5292)
                     /locus_tag="ACN3HL_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007429.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            5754..5966
                     /locus_tag="ACN3HL_002633"
     CDS             5754..5966
                     /locus_tag="ACN3HL_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007430.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(6244..8043)
                     /locus_tag="ACN3HL_002634"
     CDS             complement(6244..8043)
                     /locus_tag="ACN3HL_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HHC8007431.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         2705 a         1488 c         1565 g         2372 t
ORIGIN      
        1 tacattatgc tctttgcccg gcattcattc ctgctacatg ccctgtagcg aaagccgctg
       61 tgatattaaa gccgccagta taaccattga catccagtaa ttctcccgca aaatacagac
      121 catcaatgat tttactctcc aatgttttag gataaatttc ctttagagaa acccctccgc
      181 cagttacaaa tgatttctca ataggaaaag ttttgttgat tgatagctta aactctttgc
      241 atagttgaac aaaatcttga atttgttttt gagaggcttg ttgtcctgtc agatgatcca
      301 tttcaagccg ctcaagaaag aaaactaaca atcgctcagg caatatacca tgccaagcat
      361 tgaccaagtt ctttttggtt gctttacttt tttctgtcaa tatatgaata agctcttgtt
      421 tggtttgtgt agggaaacaa tccagagaaa gtgtcactgg ttctcccgtt ttctctaatt
      481 ctttattgac aaaacttgaa caacgcagtg cagccggacc agaaataccg aaatgggtga
      541 aaagtaaatc catcgtatgt tcagtcaata cacgaccttt tttatttaaa acgcgtaaag
      601 tgatgtcttg taaagaaagc ccttgaagtg ttttctcctg aatatacggt tcatccgata
      661 tcaaggggga ctctgtcgca taaagaggcg tcaccgtgtg acccactcgc ttcacgatct
      721 tgtacccatc tccagtagaa ccagtagatg gataagtccg tccaccagtt gttaagataa
      781 tggcaggagc atggaactct tcgaattccg tgcgtatacc gtaaatttta tgttctttgt
      841 ggatcaattt ctctactcga gtagagaata gaagcgtcac atctagttct ttcagacgat
      901 tgagcaatgc ttcgataatc gtttttgatt tatttgttac aggaaacatc cgtccatgat
      961 cctcttcttt taaatgtacg ccttgtgatt caaagaagtt catgatatcg aaattattcc
     1021 attgcgcaaa cgtactatat aaaaactttc catttccagg aatatgtgca atcaaatcat
     1081 caacaggacg attgttcgta acattgcacc gaccaccacc tgtcatcagt agtttttttc
     1141 ctgctttttt gtttttttcg atcaagagta cgcgtgcgcc ttgttcagct gcactgatcg
     1201 ctgccatcat cccgcttgtt ccagcgccga ctacgatcac atcatacagt ttttccattc
     1261 cctcacctca aggaaagtgt agcatatctg aagaaagaaa acagaaaaaa tgttttgagc
     1321 caaaagagaa aatgagctaa aatgagggaa gataagcaaa ggagcgtgga acgatgacaa
     1381 acgcaacaga atatgttcaa gcaattcaag aaaagctaca tcaaaaggat caagggcaag
     1441 aagaattttt acaagcaatc gatgaattca tgcccacggt tatgtctttt ttggacactc
     1501 atcccgaata tatcgaaaag aatatcttag aacttttaac ggaaccagaa agagttattc
     1561 aatttcgagt gccttggcaa gatgatgaag gaaactggcg agtaaataga gggtaccgta
     1621 tccaatacaa ctcagctatc ggcccttata aaggtggatt gcgcttccat cctagtgtca
     1681 atctaagtat cttgaaattt ttggcttttg aacagatttt caagaatagt ttaaccggtc
     1741 tgccaatcgg tggaggaaaa ggcggaagtg acttcgatcc taaaggaaaa tctgataatg
     1801 agatcatgcg tttttgtcaa agtttcatgc tggaattgtc aaaacatatc ggcccatcga
     1861 ttgatgttcc tgcgggagat atcggtgtag gagctagaga aatcggctat ttgttcggcg
     1921 aatataaacg attgaaaaaa tatgatactg gtgtgttgac aggtaaacct ttggattttt
     1981 ggggaagtaa gatacgtacg gaagctactg gttatggatt agtgtattat gtcaaacatc
     2041 tattgaacga agaaaaagat tcatttaatc aaaaaacagt ttttgtttcc ggaagcggga
     2101 atgtagccat ttatgcaatc gaaaaagtgc aagagctagg cgggaaagtt gttacatgtt
     2161 cagattctag cgggtacatc tatgatccag aaggaataga tgtgaaacta ttgaaagaag
     2221 tcaaagaaat caatagacaa cgtttgacgg aatacgcaaa ccaacgtcct tctgctattt
     2281 atcatgctgg agaatctgtt tggacattga aagaaaaagc ggatatcgct ttgccatgtg
     2341 ctactcaaaa tgaaatagac gaaagcttgg ccgaaatctt agtagaaaat gggatcaaaa
     2401 tcgtagcaga aggcgctaat atgccatgta cagtaaaagc tgtttctgtt cttcatgaag
     2461 caggcgtgtg gtattgtcca ggaaaagctg ctaatgctgg aggagtagca gtatctgctt
     2521 tagaaatgag tcagaacgcc cagcgattga cttgggaaag agagcaagtg gatgagcagc
     2581 tggatcaaat catggaaacg atttaccata cgtgtcgcca aacagcagcc gagtacggcg
     2641 acgaaaaaaa tctgcttctt ggagcaaatg ttgctggatt tgaaaaagtt gccaaagcaa
     2701 tggcagcaga aggtttagtt tgaaaaatga aactttcttg gaaatattgt cagcattttg
     2761 tttatttgct tgaaaaataa taaaaaaaaa cgtaaagtat tacctgtaga gtaaacctat
     2821 aaggaggaga acaaatggca cacattcatt ttgactattc aaaagtagca ccgtttgtca
     2881 acgaacaaga gttagggtac atgcaaagcc aagtaacagc agcccacaac gaattacggg
     2941 aaggtactgg cgcaggaagc gacttccgcg gctggatcga tttaccaacg aactatgaca
     3001 aagaagaatt tgcacgtatc aaagaagcag ctaaaaaaat ccaatctgat tctgaagtat
     3061 tagttgttat cggtatcggt ggttcttatt taggcgctcg tgcagcgatc gacttcttga
     3121 atcacacatt cttcaattta ttagatagca acacaagaaa agcaccacaa atcttctttg
     3181 ccggaaattc aatcagctca acatatattg ctgacttgat cgaagtaatc ggtgatcgcg
     3241 acttttcagt aaacgttatt tcaaaatctg gaacaactac tgaaccagcg attgcgttcc
     3301 gtgtattcaa agagcttctt gttaagaaat atggacaaga agaagcaaac aaacgtatct
     3361 acgctacaac agataaagca aaaggtgcag ttaaagtaga agcagatgca gaaggttggg
     3421 aaactttcgt gattcctgat gacatcggcg gacgtttctc tgtattaact gctgttggtt
     3481 tgttaccaat cgctgttagt ggtgcagata tcgatgcatt gatgcaaggt gccgctgatg
     3541 caagcaaagc atactcaagc gacaaactag aagaaaacga agcttaccaa tacgcagcaa
     3601 tgcgcaacat tctttaccgt aaaggcaaag taactgagtt gttgatcaac tatgaaccag
     3661 gaatgcaata cttctcagaa tggtggaaac aattgtatgg tgaatctgaa ggaaaagacc
     3721 aaaaaggcat ctatccttca agcgcaaact tctcaactga tttgcactct ttaggacaat
     3781 tcatccaaga aggacgtcgc aatatttttg aaacagttgt gaaggttgaa aaacctcgta
     3841 aatcaatcac aattcctgaa caagcagaag atttagacgg tctaggctac ttgcaaggaa
     3901 aagaagtgga cttcgtaaat acaaaagcat ttgaaggaac attgcttgct catacagacg
     3961 gtgacgtgcc taacttgcta gtcaaaattc cagaaatgga tgcttataca ttgggttata
     4021 caatgtactt ctttgaaatt gctgtaggta tttcaggtta cttgaatgga atcaacccat
     4081 tcgaccaacc aggtgtagaa gcttacaaga aaaacatgtt cgcacttcta ggcaaaccgg
     4141 gctttgaaga tcttgctaaa gaattgaacg aacgcctgta agataagggt ttttcgctag
     4201 atttaaataa tcagtgatag aaacatgttc gctttaaaat gaaaactggt acccatttag
     4261 gtactcaaac atactgcatc gtttattcag aataaggggc tgtgacaaga cgtttgtcac
     4321 agtcccttgt ttgtatagaa atcgattgat tgccttgctc tttagtttgt tttaggactt
     4381 taagaacagt gaggctgact tcgaaggtta attctgtttt tttgttttct agaatcagta
     4441 agcaaaaaag cactcacttc gagtgctttt ttgcgatata ttcttagctt aagataggcc
     4501 taatttttct tttacagatg agggtacctt atcgctggta attacttttt tctctatgat
     4561 ccgcttttcg cttgctttca actgcaagat cgttccttcg gtgtaagcag aaccattggc
     4621 agagtcacca gaagtaatga catcgaaatc taactgtctt ttttcaccgt tttcagcata
     4681 agcatctacg ttgtatttaa aacctcttcc aattacttcc ccattatctg ctttgatatc
     4741 agtttctgca ggcattggag ctttgactac cgcataataa tctttaccta cataagtaga
     4801 ctgatagtag tcccaacctt tccatcctat aaaagcaatc aatatgataa cgatcaaccc
     4861 taaaattttt ttcatgaaag atctcctttt ttatttttat tatattaaat attatacaga
     4921 taataacgga atattatcat cgaaacagct aacaaaattg tcataaaaaa cgagatggtt
     4981 gatattagaa cttgtgtttt tgtttaggtc tagagataaa gagagacaat ttccaaatat
     5041 atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt tacaaacgtc ttttattgat
     5101 tttccgagat ctcatcagtc gccatttgga atggttcact ccttatctag attcgtttaa
     5161 tgctcggact gcttgttcga ttgtaatacc aaacgcaacg ttattttcgt tttgtgcatc
     5221 aatcgccata aaacggttag aagttgtatc aaaagctacg cggtattgca tatttgtttt
     5281 tgtaaacgtc ataaaattca tctcctttgt aatgtaattt agttcttgaa agtttccttt
     5341 aaactttcga acttatacca agtttagcat cgtacgtttt ttgatgcaat taaaaagcat
     5401 ttatcatttt ccttatttat tttttcttaa atggtttagc tattttcttt taatccgata
     5461 agtagcccaa tcatcaaggt tacaaatact attgcttgaa tataaatcat atgctcacct
     5521 ctttataaat aacttagcaa tataaagaaa aaaacgcacg aacaacatag gaatataaac
     5581 aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat agttatctaa aaagcagaaa
     5641 gatactcaaa ataaaaaata aaaaaatgaa taaaaacgtt ttcaaataca aggtaatttg
     5701 ttattataaa ataaagaaaa aacaaaataa aaataaagaa aagagggaat gaaatggtaa
     5761 aagcagaagt aggaagatct tatatatgca aaccgatcgg agtatctcat gaactaatcg
     5821 gctgtattga acgtacatat atcaacacgg ctgtcgtgta tgttgaaagt tatgaccaac
     5881 gagactatca acttatcaat gaaagcaagt atcgcatgct cgtaaaattc tgtgatatta
     5941 gcgcacctac tgaattggtt tcttaaacag tatttttgag aattcgcaag aactccctta
     6001 taatataaat aaagacagaa gggagcgaga agatatgcca aaaagaaaaa gttcagggaa
     6061 aatgggaatt attcttgcag tgatctctgc aattcctgct attttagcta ttgttcgtgc
     6121 gatgaaggaa tcaagagaaa gttaagcaca cattatgagc gtcaaacaaa aaacgcatat
     6181 acctgcggtg gcaggttatg cgttttttgt tgtataaaga cttttttcat taacgatttt
     6241 tgattagccg actcccaaaa caaaatttag cagtttatct gaataagtga tttcttcatc
     6301 tgtttgtttc acactttcat ttagtagtcc catctcatcg gttatgatac catccacacc
     6361 ataaaacatc atgcgactca tggcatctga atcgttgatt gtccatacat atacttcttt
     6421 tccgtcttgg tgggcagaat taatgaagtt acggttgatc gtactatatt ccattgtcag
     6481 aaaatcagca ggcgtcacag ggggcccaac aatattgaaa ggtaagatgt agcccacata
     6541 aaagtttggt tctgcttctt ttaaatctga aacggtttgg tacgtcaaac tttgcaaaat
     6601 atgatggttc tctaagataa ctttgcggta tttatggaca aatcgttcga caaggtcatc
     6661 cgaatctttt ttagaggtct tgatctcaat aagtaatttt tggtttagct tatgtgcttt
     6721 ttccaaataa gaatcaaaag aacaaacagg ggcttgcact ccgttttcag taactgtaag
     6781 atttgtcaat tctttcaatg taagatcctg tggtgttcca tttacccctg ttaagtgacg
     6841 aagatttgca tcatgcatca ctacgaaatg accatctttt gtttcctgaa catccatctc
     6901 tacataatca ggatgatagt ctctgcttgt tttttcaagt gcttctaaag tattttgcgc
     6961 cccattttgg gtactcacac ctctgtgaga gacagtcact ggttttgtct gaacagctga
     7021 agtcagataa tccatattgt aaagacagac gccaataccg aaaaaaactg caaaaagagt
     7081 caaaccagtg tttttcagcg cagagaaacg caagttgggg gcttgtggga taaaccactt
     7141 agggatctca ggcaagaagc cttcgtcatc catgaaatca acaatgatat aaaaaatccc
     7201 tacggtagac atcacgatat tgaataataa aatcccttgt aaaagcgtca tagcaaacac
     7261 agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc atactttgtg ccaaaataac
     7321 aacgatatat cctaaagaag aaaggagtaa aatcgtaccg ccaatcacaa taaattggcc
     7381 cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt tcccgaatgg ctgctcgaaa
     7441 agaacgatct cgtagaatca tttccggtaa agcaaaaatc agtcgaatcc caatatagcc
     7501 aaggaaaata taaacgagta aaaaggaact gacgatgatc caacgattag caaaaataaa
     7561 atccataatg aaagcgggga tttttatttt tgacagtaga tcagaattaa aacttaatcc
     7621 gctgatcggt agaatcaata aaaaataagc aaggaaaaac aaaaaagtaa tgggtctcac
     7681 tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc aaagagattg gttctttctt
     7741 tttaataaaa aaaacactca tcaaaagaaa agtaaattcg aaataaacta acagtaaaat
     7801 cgtcatcaaa actacgatta acgagagtag aaccccagga tgttgagaaa aaattgaagg
     7861 aatattgtca taagacaaat agtcaattgc ccctcggtgt aaaataaaac gggtcgtact
     7921 gctcaataag ggtaaacaaa taaataaaat aaagccatgc atcagcaaga catcacggaa
     7981 ataagcttgt gttcctttta aaaagtccca agcattacct aagctacgtt tcaaataatt
     8041 catcctatca cctgctcttc acattgtagc gcaaatctaa tgaaaaagga aagggtgcag
     8101 tgtgttttgc agaccctttc ccagatttaa
//
LOCUS       DBGZHO010000094         8066 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.097, whole genome shotgun sequence.
ACCESSION   DBGZHO010000094 DBGZHO010000000
VERSION     DBGZHO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.097"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..883
                     /locus_tag="ACN3HL_002635"
     CDS             <1..883
                     /locus_tag="ACN3HL_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HHC8007432.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            931..3060
                     /locus_tag="ACN3HL_002636"
     CDS             931..3060
                     /locus_tag="ACN3HL_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HHC8007433.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3035..3724
                     /locus_tag="ACN3HL_002637"
     CDS             3035..3724
                     /locus_tag="ACN3HL_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007434.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4132..4817)
                     /locus_tag="ACN3HL_002638"
                     /pseudo
     CDS             complement(4132..4817)
                     /locus_tag="ACN3HL_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(4953..5120)
                     /locus_tag="ACN3HL_002639"
     CDS             complement(4953..5120)
                     /locus_tag="ACN3HL_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007435.1"
                     /translation="MYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKESEAFAKRIGG
                     RVKPIQEVRPD"
     gene            complement(5197..5637)
                     /locus_tag="ACN3HL_002640"
     CDS             complement(5197..5637)
                     /locus_tag="ACN3HL_002640"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HHC8007436.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5641..6486)
                     /locus_tag="ACN3HL_002641"
     CDS             complement(5641..6486)
                     /locus_tag="ACN3HL_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HHC8007437.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6635..8053
                     /gene="pepV"
                     /locus_tag="ACN3HL_002642"
     CDS             6635..8053
                     /gene="pepV"
                     /locus_tag="ACN3HL_002642"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HHC8007438.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2480 a         1515 c         1713 g         2358 t
ORIGIN      
        1 tatttcagta ccggttgcac tgttctcatt tatgggctcg attatggctg gaatctttgc
       61 taatatcgtc aatttcaaac aatatcaaac gatttatgct ggtttcaatc cagcggctga
      121 aagctatact tataatgact atttccaaat tggtatgatt gggatgattg taagcttagt
      181 tgtggtacta acggtcgcta atatatcaat gaacaaaaag aaacgctatg caatggcagc
      241 aaacgtacca gctgaaggtg gcgacgcacc aatgatctca tggttagccg tattattacc
      301 agttttaggg gtcgttcttt tagatcttca aatcatctta ggttttattc tagcaggtat
      361 ctgggcattg ctgtttactg gaaaattgcg cggaggttat aaagaaatct gtcgtcagtt
      421 tgcgaaatta tttacagatg gcgcagtcga tgttgcacca atggttggtt tcttgatgac
      481 cttagcgatg ttcaataatt cagctgcgta tgcttctcct tatttttcag ctatttttgg
      541 agattggata ccgcaatcac cattagtctt ggcaatcgta tttgctatat tgacaccact
      601 aggatttttc cgcggtccaa tgaatctagt cggttcaggc tcagctattt tagctgtcgt
      661 gttagctgtt aatccaacga tgtcgccagc ctttttgttc ccgttatttg caattacaac
      721 gattgctcct cagcatttag atattacaca atcttgggtt gcttggggat taggttatac
      781 aaaagtaact tctcgagaat atatgaagaa atccatccca actggttgga tcatcggtgc
      841 gatcttatgc ctgatcacgt tcttattgta cgggaacgcc tagtaaacaa aacgtcgata
      901 aaaacgatta gataaatgga ggaaaagaaa atgaaacgtt ttgtgcgaat gggaattgat
      961 gttggcggta cacatacgaa agcagtcgca atcgataatg cgacgcacga aatcatcgga
     1021 aaatcttcag tgaaaacaac ccacgatgat gtccgtggag tagctgcagg tgtcgttcag
     1081 tcttttcaaa attgtttgcg ggaaaataat atcagtccag aagatgttgt gtttgttgca
     1141 cattctacca cacaagcgac taatgcactg attgaaggag acgtagcaaa agtcggcgta
     1201 atcgggatgg caaaaggtgg attagaaggt tttttagcaa aacgacaaac tagattgaac
     1261 gatatcgatt tagggaataa gaaaaaaata gagattgtca atgcattctt acctgtcaaa
     1321 aacttaaatg tagaccgtgt ttcagaaacg atttcttctt tagaaagaga aagagcggag
     1381 gtcttggttt cttctatggc atttggagta gataatgggg aaccagaacg agttgtttat
     1441 gaagcagcat ctgtgaaagc gatccctaca acgatggctt ctgacatcac aaaattatat
     1501 ggattgacaa gaagaactcg gacagcagca atcaacgcat ctattttacc aaaaatgcta
     1561 gatacggcaa cctcgacaga agactccgta cgagaagcag gggtcaatgt ttctttgatg
     1621 attatgcgcg gagacggcgg agtaatggaa atcaatgaaa tgaaaaaacg acctgtttta
     1681 accatgcttt ccggtcctgc tgcatcagtc atgggctctt tgatgtactt gagagcgtct
     1741 aatggtgttt attttgaagt aggcggaaca acaaccaata tcggggtcat taaaaatgga
     1801 cgtccagcaa tcgattattc aattgtaggt ggccacccaa catatatctc ttcattagat
     1861 gttcgggttc taggtgtggc aggcggttcg atggtacggg ctaatcagtc aggaatcatc
     1921 gatgtcggtc cacgttctgc acatattgcc ggtctagatt atgcagtatt tacggagaca
     1981 gaaaaaatca aaggtcctaa ggttgaattt ttctctccta aagaaggaga ccctgctgat
     2041 tacgtcaagg tagtgatgga agacggagaa gaagtgacta ttacaaatac atgtgcagcc
     2101 aatgttcttg gattagtgca agaagaacat ttttcttatg gaaatgtccc atctgcacga
     2161 aaagccatac aggcattagc agactattgt catacgacgg ttgaagacat cgcagagcag
     2221 atcatggaaa aatcctatgc taagattgaa ccggtgattt tagaattggc agacaagtat
     2281 cacttggaga aagatcagat ttctcttgta ggtgtagggg gcggcgctgc ctcattgatt
     2341 acttacttta gtaataaaat gggtgtgaaa tattcgattc ctgaaaacgc cgaagtgatt
     2401 tcttctattg gtgtagcact tgcaatggtc cgagatgttg tagaacgtat catcccttcg
     2461 ccaagtaaag aagatatacg atcgttgaaa aatgaagcga tgaataaagc gattgaatca
     2521 ggcgctacac cagaatcgat cgaagtccac gtagaaatcg atccacatac ttcaaaagta
     2581 acggctatcg ctactggttc tacggaagtg aaagcaaccg atctaaccaa ggagatcaca
     2641 acagaagaag cactagagct tgctgcagag gatatgcgat taaataaaaa tgaagtttgc
     2701 ttattggaaa atacaccttt cttttatgta tgcggcgaac agaatcgttc aaaaaatgct
     2761 ggaagtcttc ggatcatcga tcaaaaagga tttatcaagg tccaacgtgg acatgcttca
     2821 tgtatgaaaa caactgcagc caattatatg acagctgtcg aacaactttg ggaagatatg
     2881 gcagtttatc aaactgaatt gattgcccga ccagaatttt atctctgctt aggagcaaga
     2941 gtctctgatt ttacagcgac ggatctggaa caactacagc ttttgatgga tctggaagta
     3001 tctactatgg aaccggagga agaagtgatc gtcgttgccg gaaatatcaa acaaacataa
     3061 gttagaagag ttactaaacg aattacaaca gatccccgaa gaaatttggg gattctacca
     3121 gtttcggcga gatttatttt ggaaaaagat tcctttgtcc aagcagaaaa ttcttataca
     3181 acaatcaatc gattgtggta tcgaaacggc atgtagcatc aaaaaaaagt acccttttgc
     3241 cgatgtagga gaaatctgtg aacaaatggc tgttccaatc gtttcctgtg aatcagagca
     3301 aataaacgaa cgaatcactt ttgcaactta tgcagaagat gaagggatcc gattgatgac
     3361 ggagccgtta gaaaaattaa aatgttcagg actagcttcg atctctaaag aaacagcgca
     3421 agctttgatt attggacatg aactatttca ccacatcgaa gcttctgtta agggaattta
     3481 tacgcaaagc gaaaaaattg tgctgtggcg gttgcctttt tatacacatc aatcaaacat
     3541 tcgtgcattg agcgagatag cagcgatgag tttttcaaaa gagatgaatc aaagcgattt
     3601 ttcgccttat gtattagagg cagtcttact ttggccatat aatgaaattc gtagccaagg
     3661 gatcttagaa gaaataaaag aaatagaaaa aagatgtacg gagtatgatt tagattacaa
     3721 ataaagagac tgtgacaaaa gtcgtgtcac agtccttttt ttccgaataa acggtgttct
     3781 cctgtcaact cctcggtcac aagtcaaaat attcaacaaa catgagaagc tgttttttga
     3841 aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttgga aaaaggtgtt
     3901 caaaagcttg catctgcggt aataagaaca gccaagttaa aaacataaga agctattttt
     3961 acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctc aataaacggt
     4021 gtgcaatcag ctgaccctcg gtattagctc aaaaaaaacg gcaaaatatg aggaactatt
     4081 ttgccgttta tttctctaat actcaggtca aaacgctgat tccaaaacct cttatttgat
     4141 gggtctgtcc tgaatatctt caaaataatc ggggtaatta tgaatcacgt attcttgctc
     4201 ctcgataatc atatgtaaat gcatcgtgca aagaaatccg acttcatcaa agttatgatc
     4261 aatcattgat tgaagcattg tctgatgttc atctaatact cgaccccagt ctaattctga
     4321 aatcgtcaaa cgtaaccatc tgaaacggtt caagtgcgta ctataacttt ctagccaatc
     4381 ccaaatttct cgttttccag caatttcata acaagttcgg tgaaaatcag tatccaaatc
     4441 aaaaaagctt ttttattttg agcgatcact gcctgatcgg tttgttctag tattttttct
     4501 agtttagctt gatcttgctt ggtcattttc gcactgcatt cttgcaggat cggtttttcc
     4561 aacttttccc gcgtataacg ggctaatgaa gcagatcgga tatcgatttt tgaaacataa
     4621 gtgccggact gtggaatggt ttttacaagc tcttgattgc gcagttggat cagtgcttct
     4681 cgaatcggtg tacgcccgat agctagttgt tcttctaaca ctttatcgga gattttactt
     4741 ccgggtgcta actcggaata aatgatttgt ttacgtatag attcataagc ttgctgttgc
     4801 aaattattga taaccattta accttccttt ctatgcagat ataatctatt ataacataaa
     4861 tcgcttacaa atcgtgtggg cataaaaaca cagtctgcaa aaaaagccct gataggcatg
     4921 cctattagag cctcgaaaag aaaaatattg aatcaatctg gtcgtacctc ttggatcggt
     4981 ttgacacgac cgccgattct tttagcaaaa gcttcggatt cttttttgtc tttgaaaatg
     5041 agcagattgt ctaagttttt ttcccgagtg cgacagccag ttttatcgat gtaaccgtgc
     5101 attactttaa cgacatacat ggggatcacc tgcttttttc ttttcattat acgaactact
     5161 cgacacaata caagaaaaat gcttagacgg tctttattaa gaatttacat catccaaaga
     5221 agcgtacgct tggaataact gttctaactc cggattgact ttgctcagct tcactaatcg
     5281 ttgcgaatca gaaagtaaaa aacagtgttt actactgcca gtagttttta attttttgtc
     5341 ttcagttccc acaatttcgt agctaaaatc caaccgtgtt cccgtatact tttggatagt
     5401 tgggtggatg ctcacttttt ctccgtaatg gatcatttct ttatagctgc aatttacttc
     5461 cagaacgggg atgatgatcc cagattcttc gattttttta tagggaaacc ctagatgtac
     5521 caataaggct acccgagcct cttcaaacca gcggatataa ttgctgtgat gaataatccc
     5581 catttgatct gtttcataat aaaaaggttc tcgcacataa cctgtaaatt tctccatgac
     5641 tcatgcctcg ttttccattg attttttaca aaaataattc atccacttcg gaagtgcttc
     5701 gctgatttgt gtcggcaaaa caatatattg ttcttttgcc agctggtctc caatgaaact
     5761 atgaagataa acagctgctg caatcgtttg gtcattttga ggaaactggg ctaaaaatcc
     5821 tgtgatcatc ccagctaaag tgtcacccat gccgcctgtt gccatagcag cagaacctaa
     5881 aggattggtg tagaagtgct ggtgaccata aatttttgtc tcatgacttt tcaaaacgag
     5941 cacagcaccg atttcctgtt gcttcttttt gttttcttta tcccgttgtt cttgtatcgg
     6001 tagagaactc aaccgttgcc actccatttg atgaggtgta agtacagttt gttcgggata
     6061 gggtagcaaa agatgattag caacaagtaa acttaaagca gagccatcaa tcaccagcca
     6121 ttgttctttt gattggtttt ctagtacttg tttgaaacgt tccaaactct tagaagaagt
     6181 acccaatccg ggaccaatca agagtacatc tgcttgcttt attacggaaa gaaactggtc
     6241 agtatccgtc caatctacaa tcattgcttc tggcagatga ctgtgaagag cactccgatt
     6301 tttttcatca gttactacag tcgtgagacc cgctccactg tgtacggcag ctaaagcact
     6361 cataatgatt gctccgccat attgttcatt gccgccaatc aaaacgatac gtccaaatgt
     6421 tcctttatgt gaaatctttg gacgaggtgt gatgactctt ttcactagtt gttcgtttat
     6481 cagcatcgaa aaacctcctt ttactcatta tagcgtatat tttttttaga gaaaaacaga
     6541 taagaaaagg aattgtcaga ttttttgaac tatttttttc tgtaatttgt ggtatcatga
     6601 acacgaagac ttaaataagt ggaggattaa ctttatgaca attgattggc aaaaagaagt
     6661 agaagcacgt aaagaagact tgcttgaaga cttgaaaaat cttttacgtg tcaacagcga
     6721 gcgcgatgat tcaaaagtaa caccagatgc accatttgga cctggacctc gcgacgcatt
     6781 gaaacatatg ttagcttatg gcgaacgtga tggatttaaa gtaaaaaatg tcgataacta
     6841 tgcagggcat attgatcttg gcgaaggaga cgaaacgcta gggatatttg gacacatgga
     6901 tgtcgttcct gcaggagatg gctgggacac agatccttat gaaccagtaa tcaaggatgg
     6961 aaagatcttt gcacgcggat caagcgatga caaaggtcca agtatggcag cttactatgc
     7021 gatgaagatc attaaagaac ttgacttgaa actatcaaaa aaagttcgct tcgtagtcgg
     7081 cagcgatgaa gaaagcggct ggggcgatat ggcttattat ttcgaacatg aagaagaacc
     7141 agattttggt ttctcaccag atgctgaatt cccaatcatc aatggtgaaa aaggaaatgt
     7201 ttctttagct ttacgcttca aaggcgacaa tgcaggagat tatgtcttga aatcttttgt
     7261 ttccggactt cgcgaaaata tggtgccagg aacagcaact gcagcacttc aagtaccaag
     7321 tgcagatgca gctatcgcga tggaagaagc attttaccaa ttcatcgaag caaatccagt
     7381 aagcggaacg attgaagcgg acaatacgta tgtaaaaatc gaattagttg gtaaaggcgc
     7441 acatggtgca agcccacaat ctggtatcaa tgcaggttct ttcttggcat tgttcttaga
     7501 taactatgaa ttcctaggat ctgctaaaca atttatccat gtagcagctg cttatgtcca
     7561 tgaagatttt tatggagaaa aactaggagt cgcttatgaa gatgaaaaaa tgggcaaatt
     7621 gacaatgaat gctggactat ttgcttttga agaaaatggt acagaggaag cgaacttcat
     7681 caatatgaat ttccgttttc caaaaggtgt aacagtagac ggattgcaaa gtgacatcga
     7741 acaaacagtg gggcaagaag gcgcaacagt tactcgaggt gctcgcgtaa tggaaccaca
     7801 ttacgtacca atggatgatc cattggtggc tacattattg caagtctatg aagaccacac
     7861 tggagaaaaa ggctacgaac aaatcatcgg tggcggaact tacggacgtt tgttgaaacg
     7921 tggcgttgct tatggagcga tgttcccagg atatactgat acaatgcatc aagcaaacga
     7981 atttatgagt cttgatgact tgttcagagc aacagcaatc tatgcagatg ccatctatcg
     8041 tttggcgaaa taaaaatact aaaaaa
//
LOCUS       DBGZHO010000095         7858 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.099, whole genome shotgun sequence.
ACCESSION   DBGZHO010000095 DBGZHO010000000
VERSION     DBGZHO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.099"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..225)
                     /locus_tag="ACN3HL_002643"
     CDS             complement(<1..225)
                     /locus_tag="ACN3HL_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8007439.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHL"
     gene            331..1062
                     /locus_tag="ACN3HL_002644"
     CDS             331..1062
                     /locus_tag="ACN3HL_002644"
                     /inference="COORDINATES: protein motif:HMM:NF019736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007440.1"
                     /translation="MLSEKEQENFDEYAYFVNTAIDRQSLGKVLGGKMISVVEPYYEW
                     IMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAAHAAVAYLGALKGYKTIQEAI
                     QNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKTLNRHGNQKLSDEITRVGSSP
                     IRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYRNLADPEAEQLRRMIVNDGLK
                     ATIKKISRLEGKLLNEVVAAYESQI"
     gene            1074..1505
                     /locus_tag="ACN3HL_002645"
     CDS             1074..1505
                     /locus_tag="ACN3HL_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8007441.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            1519..2964
                     /locus_tag="ACN3HL_002646"
     CDS             1519..2964
                     /locus_tag="ACN3HL_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HHC8007442.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            3250..4875
                     /locus_tag="ACN3HL_002647"
     CDS             3250..4875
                     /locus_tag="ACN3HL_002647"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HHC8007443.1"
                     /translation="MKKIYSKEIDCFRGLAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            5507..5860
                     /locus_tag="ACN3HL_002648"
     CDS             5507..5860
                     /locus_tag="ACN3HL_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007444.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
     gene            6641..>7858
                     /locus_tag="ACN3HL_002649"
     CDS             6641..>7858
                     /locus_tag="ACN3HL_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007445.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKIL"
BASE COUNT         2752 a         1068 c         1457 g         2581 t
ORIGIN      
        1 gagatgaagt tccccgtact cggtcttgac cgtacggtca taggagccgt tacgagaatt
       61 acccgtgtta aaaccaatgc gatcgtactt ttcgtaatcg aggaaagccg ttaactccgt
      121 tttgagaagc gtattgacag ctttttccaa atggacacgg aataattcat tcaaatcgcc
      181 tttgttcgct agagtcttta gaatttctgt agtaaaatcg ttcatatgga agtcctcttt
      241 tctgtgaatg tgttgtggta actctattct acagaaggga cttccttttt tctatttaca
      301 caaaatattt tacactctca aatttattct ttgctgtcag aaaaagaaca agagaatttt
      361 gatgaatatg catattttgt gaatacggca atcgatcgac aatctttagg aaaagttctt
      421 ggaggaaaaa tgatctctgt tgtcgaacct tattatgaat ggataatgga tcgacagcag
      481 ttagatccaa ctacatcttt tgatatgaaa aatgtaaatt tggttgatga tatggagcct
      541 tacattgagc gaaagcttta tatcgttaat gctgctcatg cggcagtagc ttatttaggc
      601 gcactgaaag gatataagac gattcaagaa gcaatccaaa atatggagat tttcaatcta
      661 gtcaagcaat ttttaatgga gaatatagag tactttgtac aaaaatatca tttttctaga
      721 gaagaattaa catcttttgt ggaaaaaaca ttaaaccgtc atgggaatca gaaactctcc
      781 gatgaaatta ctcgtgtagg aagttcccct attcgaaaat taggccctaa tgatcgttta
      841 attgctccca tagtaaaact agattcatat catttacctt acgatgcagg aataaaagta
      901 attgctgcgg gatatcatta tcggaatctt gctgatccag aagctgaaca actacgtcga
      961 atgattgtaa atgatgggtt gaaagcaacg attaaaaaga tttctcgttt ggaaggtaag
     1021 ctgctgaatg aagttgtcgc tgcttatgag tcccagattt agaggaggag aatatgctaa
     1081 aagaacaatt gtcaggaaat acaatgttta tggatgcgat cgattcatgg caagaggcaa
     1141 tccgagtaag tgcgcgtcct ttgataggaa agggaataat agaggaaagc tatgtacaag
     1201 cgatgataca aaatgtgttg gataacggaa attatattat attactgcca ctagtagcaa
     1261 tgcctcatgc gcgtccagaa tttgggagca aaggggtcgg gatgagcttt ttatgtttag
     1321 ataagccagt catgttccca agtgaagaac cagtaaaatt cttctttacc ttttcttctg
     1381 attcgccaaa gggacattta gacttaatgg ccaatcttgg agaattgctg agtgatgaaa
     1441 aaatgtatca aaaattattc gatgtgaaga cagaaaaagc attgttagat ttgataaaga
     1501 agtaaaggag agaagaaaat ggaggtagca aacaaaaaaa aacgagtctc catgcgagct
     1561 aaagttcaag cgattggcgg tttcttaaca aatatggtat tgccaaatat aggcgcattt
     1621 attgcatggg gaattgttac tgcattattc attccaactg ggtggttccc aaatgaatct
     1681 ctgaatgaac tcgtaagtcc gacagtcagc tatctattgc cgttactact tgcctatact
     1741 ggtggtcgga tggttggtgg tacacgtgga gctgttttag gtacaatcgg aacaataggt
     1801 ttgattattg gtgctgacat accaatgttc atgggagcaa tgattatggg gccacttggt
     1861 gggtggatga tgaaaaaaac agatgatttt ttagatggga aagttcctgc tggttttgaa
     1921 atggtcgtca ataatttttc tataggaatt attggtttca tactgatgtg cctttcttat
     1981 ctggtagttg gaccaataat ccaatcagct aatcaatttg taacgagtgc aattgaagca
     2041 ttagtttcaa ctggtttttt accgatactg tccttaatca acgaaccggc aaaagtctta
     2101 tttttaaata atgttattga ccaaggtgtt tattatccat taggtatgca acaaacatta
     2161 gaggcaggca gatcaattta tttcatggta gcatcaaatc ctggccctgg cttaggacta
     2221 ttgttagctt attctttatt tggtaaaaag gcagcaaaac agacagcacc aggtgcaatc
     2281 atcatccatt ttttcggcgg aatacatgag atttattttc catatgtatt aatgaaacca
     2341 ctcactatat tatctatgat tgctggtgga atgacaggaa tcatcacttt tgaattattt
     2401 gatgcgggcc tggtagcagg tccaagtcca ggttctattt tttcttattt agctctaacg
     2461 cctcggggaa attttttggg tgtcatggcg ggagtggtca cagcaacact ggtttccttt
     2521 tttgtaacat cagtaatttt aaaagcagat aaatcaacag atgaagacag aaattttgaa
     2581 ctatcagttc aaaaatcgaa aacgatgaaa tcagaaggaa gaaaattatt aaaagaagaa
     2641 aatgctagag aaatatgtac cgagaaaaaa gagatgaata aaatttcctt tgcttgtgat
     2701 gcaggaatgg gaagcagcgc aatgggcgca acaatattca agaaaaaatt gcaaaaagca
     2761 ggtattactg atgttgagat aaaaaattat cgaattgaag aggtaccaga agatagtgat
     2821 ttggtgatcg tacatcaaga tttggaggaa cggactagaa aagcacatcc taacatgaaa
     2881 attgtgacat taaagaatta tttgcaagat ccagtaatca atggattagc agaagaaatc
     2941 attggattaa aaacagaaga ctaatttatg ggaatttttg attaaccttt attaaaatta
     3001 ttttgcctaa tataaaaagg ttgtgacatg gcttgtgtcg caaccttttt ttgtcgcaca
     3061 aataattaat cggatatttt atgttcatat tttttgtgat caacgagaac tgatggggca
     3121 aagatacatt ttagatactt ttaactgtta atttacaaaa caaggtgaaa cgaatagaaa
     3181 aatgaaaaaa tcgatacgga agaatatgtt tgattaaaac atgcatgaag agaaggaggt
     3241 tgatgataca tgaaaaaaat atattcaaag gaaatcgatt gttttagagg ccttgctgtt
     3301 ttagcagtga tattttatca tttgccaaat agtttgctgc caggcggatt gcaaggagta
     3361 acgatctttt ttgtggtttc tggtttttta atggctaaaa atacgataag agatgaaaaa
     3421 aacagacaat tcagtttttt acatttttac tataagcgta tcaaacgtat ttatccattt
     3481 ttactgtttt ctttggtcgt attcattttc atactaggga ttagcaacat tcgattgata
     3541 ggaaacattc gtagtgagct acccagtttg atttttggct ataacaattg gtggcagctg
     3601 aatcaaggag tatcttattt tgactcttac tttaatgctt ctttatttaa acattattgg
     3661 tcgctttcag ttgaactaca attctatttg atatggccat ttttgtttat tgtcattaag
     3721 cgtatgagaa gaaaacaagt gttttactta atctatacat tgatttttgt ttctattctt
     3781 tttagtttgt ttttaccttc aactaaggca tattatcata cgatagctaa actttttcca
     3841 tttttattag gagtttgggg gtattttaat cgaataacta ttggccgttt ctttgaacaa
     3901 aacactttta gtaaaatctg gcttttatta ctagctagtc tttgtctgat tctgttcccg
     3961 atttttcctt atacactaaa tgaactactg atcagtattt gttttgctct attgttagcc
     4021 agtgtcgatg atatgaacat tgcaaaaaag accaaaatcg ctagtacaaa actttctttt
     4081 gtaggaaaaa tcagttatga actttatttg gtgcatttcc cagtattgat tgctctgaca
     4141 aatctattca aacatcacca ttggaaatat ttggatatcg caggtctatt cactgtgttt
     4201 ttatgtacat tactcatgat tacttgcttt agaaaaggag tgcaaaagat gagatcaccc
     4261 aaaatttgga cagctatggc actaatgata atcggagttt ctgtactggt attacgtgct
     4321 cctgccagtc gactgaccgc tgaccaaaat cagttgcaaa gtttattaaa agaaaactct
     4381 agtaaagcaa atgcaggaga aaatctgttg tcacaagaga agaaaatatt atttatcggt
     4441 gattctgtta tgctgggggc gtatcaggaa ctaaaggaga catttaaaaa agaagcattg
     4501 gtagatgcaa aagaatcaag acaaatcact gcgttaccag aaatcttaaa ggagcataaa
     4561 gatttagttt cttaccaaca aatagtgatc gggttaggaa ccaatggtgt gataacagat
     4621 gaagctatag aacaaacaat gtctttgctg aaagataaaa aagtatactg ggtaaatata
     4681 aaagcaccaa ctggctggca agatacgata aatgccacat tagctacatt gccaaatcag
     4741 tattctaata taacgatgat cgattggtat agtgagagca aaaatcatcc tgaatttttt
     4801 tatgatgatg aaacccattt gaatgaaagt ggacgtacag cttatgcaaa gtatattgct
     4861 tcagttattc aataaggtag tgattacgtg tgttaacctt actttttcct aataggtgaa
     4921 tcaatttaaa taaaaaatac ttcatatgat aaacggtgtt taagaggagg agctttttaa
     4981 tattcgtggt aaaaaagaga tgggcgaggt cgttaactga gagcttcttg gaaagaaatc
     5041 gctttggatt tatcctcttt gttatacaga acatgagcga gacgacaata ctaggatgta
     5101 tgttctgatc gaagttttat ggttacaagc agcaatcagc ttagataaaa ttaaggatcg
     5161 taggaaccaa gtaaagaagg ctgttagtaa agaaacaaac gatcaagtat gttttactct
     5221 taagaagatg cagtgaataa ataatagtaa tataatgcta gaagggactg tgacaaaaga
     5281 cgtgtcacag ccttttttgt tattttaatt atcgtccagt ctttttttat aaatgattgc
     5341 ttaagcatta aatattaaaa aatatagagt tcaaaattac tgcacaatta gatgaaaaat
     5401 ttgaacaaca aaaagtgtat ttttatacta taatagcttt tgaatttagt tactctattc
     5461 aaaagttatg ctatggacaa gaaaaagaat aaatagaggt gagaaaatga atagtttcaa
     5521 gaaaaaattt gtgagtagat ttttaaatat gaaaaatttt tttgaaaaaa agggagatta
     5581 tgatgcatat aattatgtat taaatctaga aaagcaaaca tattatacac tacgtaaaaa
     5641 cgatgataat gacttttgga ctatgttacc taaaatgctt tcgattgact ctaagctttc
     5701 ccttttagag gaatttatta atttagacat tgaagaattt tgcgggggaa aagagttaat
     5761 taatatggta gagagtgatt atcataccta ttataaagaa agttgtggat acaaagtgga
     5821 tgagcaatgt ccacaatcaa ttatttttta cattgagtaa tatgaactat taagcaggaa
     5881 agcaactaga agctactgat ttagtattta caaatataaa ctatattgct aacaattatt
     5941 ttctagaagg aataaaagaa ctaagaatca agacgttatc ttgattctta gttcttttaa
     6001 catggaaaag atggataatg cactgttaat tcatgatgca tcatcagaaa agttggaagg
     6061 agaagataga aatcattaaa tgatttctac agatggtaaa tgaaaaaaca aaatattagc
     6121 aaaaatttgc ctaaatagat agtaacactt tctaaattaa atacaagcgc attcataaaa
     6181 tgtttataca aatatctatg tgataaaaat tggatatgtt cacaataaat aggaattaaa
     6241 ataacgaatt tacgtttgtt tttatttacc aatcaaatta tcttaatgca ggaataaaaa
     6301 attaaattac atattgttaa tcatttacat ctccattaat aactcaaaat gaaaagatgt
     6361 ttttattttt attctatatt tcagaaaaaa attaaactag attataataa ttcttcatgt
     6421 aaaaataaaa acaattacag ctatgatgtt taagataaaa caattatgaa atcgatatcc
     6481 gtttatatac ttatcataag ctagaagcaa ataactagcc tatgtatgta agtgagatta
     6541 tatttattaa aaggcttctt ttgttcgatc agttatagtc gaacgagaga agtttattct
     6601 ttgattaaaa taaacaaaag taacttattg aggtgaaatg atgcaaactt ttttaactaa
     6661 aacatctttc aaaaaagtag ttttattaga ttatttgtta gaaaaagaca attggtgtgc
     6721 aatggaagaa cttagaaatt tacttaatgt tacggagaag tcagtcttac actatataga
     6781 agaactagag gatttattta agcaatataa tggtaatatc cttctgaaaa atgaagataa
     6841 taaacgattt ttcataaaaa aagagaaaga ttttcctatt tataatattt atcttcattt
     6901 ttataaagct tcttataatt atcatttgat tgattttatg tataaatatc ctagaagtgt
     6961 tctaaaagat tttgctaaag agcaatttac tagtgtatct actgttttca gatatgcgaa
     7021 gctcttaatt ccatatttta ggcgttatca tataacattt catccatttc agttagaatt
     7081 gaatgcatca gaggcaaaca ttcgtagctt tttttattat ttctattgga attctacacg
     7141 tgaaagtagt gataagtggc catttcatat cgaacaaaag gaaatagaga agtatatagt
     7201 tgcttttgag gggatttatg atattacgtt aactattttt caaaaacgtg tattttcttt
     7261 ttggttagcc attaatatag aaagaagttc atttagaaaa gtacgagtag ataatgaata
     7321 taaatcagtt atctcagatg atccgcattt taatcttttg aagaagtggt caaaacaaat
     7381 caatctttct tttaacagcg atgaactgtg tttcctttat cgaataattt attcttttgg
     7441 agtaattgat ggaaatgcaa tatatgaaaa tagtcatgca tatgcacatc agcgacaaaa
     7501 tacttgttct tatcgagcag ttgagaattt ggagaaagtt ttacaaagca tgttccgttt
     7561 ttctttagat ataaaggatc cagaactcat attcaatttt attgcatttc atgaaagaag
     7621 ttatctattt tatggtaatc cagatctttt ttttaatcgt tcgtatatcg aagaaatgaa
     7681 agaagaagaa cctcgaactt atcacataat ggaaaaactc aaaaaagaat tacaagcaaa
     7741 tgcggatttg gatgtatcaa agaaattaga aaactgggca caattatttt tggattatta
     7801 ttatgtgtta gattattatg atttattttt aacaaatgtt aaaccgatta agatttta
//
LOCUS       DBGZHO010000096         7760 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.100, whole genome shotgun sequence.
ACCESSION   DBGZHO010000096 DBGZHO010000000
VERSION     DBGZHO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.100"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="ACN3HL_002650"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="ACN3HL_002650"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HHC8007446.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="ACN3HL_002651"
     CDS             complement(2032..3285)
                     /locus_tag="ACN3HL_002651"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HHC8007447.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="ACN3HL_002652"
     CDS             complement(3291..4214)
                     /locus_tag="ACN3HL_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HHC8007448.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="ACN3HL_002653"
     CDS             complement(4435..6927)
                     /locus_tag="ACN3HL_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HHC8007449.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="ACN3HL_002654"
     CDS             complement(6934..7401)
                     /locus_tag="ACN3HL_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HHC8007450.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="ACN3HL_002655"
     tRNA            complement(7537..7610)
                     /locus_tag="ACN3HL_002655"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="ACN3HL_002656"
     tRNA            complement(7668..7741)
                     /locus_tag="ACN3HL_002656"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DBGZHO010000097         7598 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.101, whole genome shotgun sequence.
ACCESSION   DBGZHO010000097 DBGZHO010000000
VERSION     DBGZHO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.101"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(136..426)
                     /locus_tag="ACN3HL_002657"
     CDS             complement(136..426)
                     /locus_tag="ACN3HL_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007451.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(544..804)
                     /locus_tag="ACN3HL_002658"
     CDS             complement(544..804)
                     /locus_tag="ACN3HL_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007452.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(941..1354)
                     /locus_tag="ACN3HL_002659"
     CDS             complement(941..1354)
                     /locus_tag="ACN3HL_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HHC8007453.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="ACN3HL_002660"
     CDS             complement(1810..2295)
                     /locus_tag="ACN3HL_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007454.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="ACN3HL_002661"
     CDS             complement(2434..2649)
                     /locus_tag="ACN3HL_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HHC8007455.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="ACN3HL_002662"
     CDS             2873..3673
                     /locus_tag="ACN3HL_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8007456.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="ACN3HL_002663"
     CDS             3692..5560
                     /locus_tag="ACN3HL_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHC8007457.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="ACN3HL_002664"
     CDS             5553..6044
                     /locus_tag="ACN3HL_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HHC8007458.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /locus_tag="ACN3HL_002665"
     CDS             6032..6586
                     /locus_tag="ACN3HL_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HHC8007459.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="ACN3HL_002666"
     CDS             6604..>7598
                     /locus_tag="ACN3HL_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HHC8007460.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DBGZHO010000098         6079 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.103, whole genome shotgun sequence.
ACCESSION   DBGZHO010000098 DBGZHO010000000
VERSION     DBGZHO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.103"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..411
                     /locus_tag="ACN3HL_002667"
     CDS             <1..411
                     /locus_tag="ACN3HL_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007461.1"
                     /translation="LIGGYFLLNLDSVNSNAQIKDQRVAEHNNKKMSLTKNIYSMSDE
                     ELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSELVSYKQNHRQFIDVN
                     TDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            425..1114
                     /locus_tag="ACN3HL_002668"
     CDS             425..1114
                     /locus_tag="ACN3HL_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007462.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1239..3590
                     /locus_tag="ACN3HL_002669"
     CDS             1239..3590
                     /locus_tag="ACN3HL_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HHC8007463.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3670..4065
                     /locus_tag="ACN3HL_002670"
     CDS             3670..4065
                     /locus_tag="ACN3HL_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007464.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4390..5007
                     /locus_tag="ACN3HL_002671"
     CDS             4390..5007
                     /locus_tag="ACN3HL_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007465.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5048..5347
                     /locus_tag="ACN3HL_002672"
     CDS             5048..5347
                     /locus_tag="ACN3HL_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HHC8007466.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5381..5548
                     /locus_tag="ACN3HL_002673"
     CDS             5381..5548
                     /locus_tag="ACN3HL_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHC8007467.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5593..>6079)
                     /locus_tag="ACN3HL_002674"
     CDS             complement(5593..>6079)
                     /locus_tag="ACN3HL_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007468.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNPSLDRLGRDYEDIKNTVAFMKQK
                     KVALKILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKA
                     GRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKAND
                     L"
BASE COUNT         2085 a          843 c         1226 g         1925 t
ORIGIN      
        1 ttaattgggg gctattttct tttgaattta gattctgtta attcaaacgc tcaaataaaa
       61 gatcaaagag tagctgaaca taataataaa aaaatgagtt tgaccaaaaa tatctattct
      121 atgtcagatg aagaattgta taaagaattt ggtgatttat ccggggaaca gttagaagaa
      181 agtattccag gaattagtga ctcagataaa attgttgtct tgtctgctgg tgggcaatta
      241 atgggagatg gcaaatccga attagttagt tataaacaaa atcacagaca gtttattgat
      301 gttaatactg attccaacgc tatttcgatt aaggatctaa aagagctttt aaatagtaaa
      361 agaaatgaat taaagcagat aaaagaaact aattcagtgg aattagagta aaggaagatt
      421 cattatgaaa aagatttttg gtgtttctgt tgggctactt atgatgttaa catttggaaa
      481 tgcagtatat gctgctgaga aagaagttat ttcagatcca gagcagtacg cctcacgata
      541 ctttgctgat tttgaagaag aagataaagt acttgcattg ccagaaggtg gttttttaaa
      601 aggggaagct aaaattgtat ctatggataa tccagatata attcaaggtt catataattc
      661 agaaactgat cctgcttcag tttcagtgac agaagcaaaa aaaattgttg ctgaaaaatt
      721 caaaaatgat attgaaacta ctccaattat gcctcgagga gcatttccac ccgatgttgg
      781 tactagcgga caccttcttg tactagcagg aggaggaagc tataaatcac agccatttag
      841 tggtgcggga tggcgttttg gaggtatggg tgtaaaacca gctgatggta caggcaactt
      901 tttacgttgg aaatcctaca ttgacgatgg aagagtagga aatgtaaatc aagccaacgc
      961 aactaaatct ggttctattc aaggaatggc attgtatgct cgtgaaggat tcaaatactt
     1021 tgcaccaaac gggcctggtt ggacaatgaa tataggtatt tattacactt ataatcctgt
     1081 tgcaggtacg tattatgttg ttcaaaatat ttaataaaac agcacaaaga gatttctttg
     1141 tgctgtttta ttatttttag ttgttgacaa acactaaaat ataaaatata atcaacacat
     1201 aaacgaacgt atgttcggca agaaagcagg ggatttttat ggatgagatg gttttaagta
     1261 ctcagaaatg gctaaacaag aaatacagta atgttacagg gtttgataag gttccagaaa
     1321 atgggcgaac agggtggcct acaatctatg gacttattga aggactacaa gtagaacttg
     1381 gtattactaa tctagtagct aattttggac ctaccactga aaaaatgtac gataatcagg
     1441 ttactcctaa atggggcaaa aatctaccta aaaatattgt atttcttatt caaggtgcct
     1501 tttggtgtaa ggggattaat ccaggtggct tcgatggggt atatactcca tatttagata
     1561 ctgctgtaaa agagttgcag actgatgcag ggtttaatgg aagcgctgta actggagttt
     1621 tggatgcgaa atgggccaaa gcgttatttg atatgagtgc ttttgttctt gttcccggcg
     1681 gagatagtaa aattagaaaa atgcagcaat ggttaaatgt aaattattta gaatacacgg
     1741 gaataatgcc ttgtgatggt atttatcaaa gaaattcaaa tcaagcatta atttttgcat
     1801 tacaagctga actaggatat tctcccagtg aagcaacagg gtcttatggt aatgggacaa
     1861 ctagtaaaac ttatcctgtg tctgaaggta actcgggaaa ctatgtaaga ataattcaat
     1921 atggattata tgttaatggt tattttgaag acggtacatt cgatggtatt ttcactaaat
     1981 atatgggttt agaagtactg gcattccgaa aatttatggt attgcctgaa tatactgaaa
     2041 tagcagatgt tgttgtaata aaaggactat tgtctagcgc tggagatatt agaagatctg
     2101 cagatggcgc agatacttct acgcaattaa ctagatctca aatccaaaca ttggttgata
     2161 atgatataaa aatagttggt agatatctta ctggtactgt tggaattgga aaagatgaac
     2221 gaaataagta tctaactaca gaggaattga ataatatttt ttctaaaaat ttatctgtgt
     2281 ttcctatcta tcaagatgga ggtgcagcat tagcttattt tacttatgat cgtggcttat
     2341 cagatggtaa gaaggctata gatgcagcaa aaaatctaaa tataccatta acaacagtta
     2401 tttattttgc tgttgatcta gacatgttag gggaagaaat tcttgcatat gctggagaat
     2461 attttaaggg ggtatctgct gtaatgtcat atagcgggta tcaaacgggt gtttacggaa
     2521 caagaaatgt ttgttctcaa ataatcaata acgggtatgc ttcgtttgca tttgtttcag
     2581 atatgtcgac tggttatagt gggaatttag gttttcctat gcctagacaa tggtcttttg
     2641 atcaatttgt tgaatttacc ataggaagtg gcaacggagc tgttggtatc gatttaatcg
     2701 ctacatcggg tagagatagc ggatttaatg agttatcaaa tgatactaat aatgataatt
     2761 acattgccaa atacaatcag aaggttataa atcagatggt acgtgcgtat caatatctat
     2821 cacaagctgg tcttgataat ccttggaacc ctcatttgac attttataga tatgtaaatt
     2881 attctggttt gtcatgggac atcatttctt ctcctgtaac agagcatgat agaaaaattt
     2941 atgatgaata taggaataaa ttaactaata gcgagggcct gtataattat tttatagatc
     3001 ctaatactgg ttcaataata ggtttgcctc acttaattgt gacgttacaa tcacagatgt
     3061 ttctagccga cacaatcaat gatagtgttt ctgactttgc aggttggtta ggagatttaa
     3121 tgacttgctg gggtgaagtt aagaaattag gaatacaaat ggagcaaggt gtatttgcat
     3181 tagtaggtac ggctgcaggt ggaacattta gtctagaaga tttataccaa gatgttgacg
     3241 cggtaaatgt ttatacctta gcaaaaagaa attctgattc aacagcttta tcggctttaa
     3301 aaacgtacta ttgtgataag ggtgctattg atagatttaa tcaatttgtt aagaacagat
     3361 ttggttcttc agataaaatc gcttcagtaa caaatagttt attagaaaat gacgaaacag
     3421 ttgatatctt aggtgtaggg ataatttcat ttttcattga taaaatagtt aataattcac
     3481 ttgggacaga ttttacttat cttgatttta ttggagatga ggggaaagtt gcaaatggat
     3541 tttctgaaaa aattattcaa tttcaagaaa atagaagtaa acttaattaa gaatcgttta
     3601 ctatttaaac agtgtccttt tcctttttaa atatatacga taaaataagt atatgaattg
     3661 taaaaggaca tgatgattat ggaagaaata gaatggaata atctgactca aaataataaa
     3721 aataattctg gatgtggaat tatctttatg tttgttatag ttttgggaat agtagtactt
     3781 ttaataactg tcaagatagt agattacttt gcgaatactc ctgaagaaca aatacagaga
     3841 aaacttcctg agtttgaaag agtaccacct tatgatccaa gagataattc atttcaagta
     3901 aaaaaattaa aagagtctcc aaatgaaatg tggtttgaag ttacagttga atcaagcgac
     3961 ttcaaagaaa aaaagaaaga atacaattat attgtaaagg caaaagtatc aaaaagattt
     4021 atttttaacc ctaaattaga aatatatagt gttgtaatag aataatagtg ttaaaaaaat
     4081 tgtaaaagtt aaagaagtca aattctgatg tgaaaaataa aatataccat ggaagacata
     4141 aaagaaaaac tggataacta gtttatttaa tggcagaccg ttaaggcctg ccatttttat
     4201 gtattttagc ggaataaata taatcatgcg ggagtgtaaa cttactgttt caaaaagtat
     4261 actttttgac atgccttgat tttctttgtt tatgtatggc ataataacca cataatacaa
     4321 tttgaaacgt ttctgattta atctgattgt tttgaaacaa ttttagtgaa aaaagggtag
     4381 ataaaaacga tgagaaaatt tttttatatc cgggtcagta gttatgatca atcgatcgaa
     4441 cgacaactga tttccgcgaa ggaattagga atccctgaag aatatatatt tgtagaaaaa
     4501 gccagcggca aagattttaa acgccctgaa tatcaattaa tgaaacggat gtttcgaaaa
     4561 ggagatttac tctatctaca atcattagat agactaggca gaaataaaca aatgatttta
     4621 gaagaatggc gagaattaac taaggaaaag cagattgata tttctgtgtt agacatgcct
     4681 ctgttagata ctgctagtta caagcaacta gatgggttag agacgcttat ctctgactta
     4741 attctgcaat tactcagcta tatggccgaa gacgagcgga aacgaattaa tagccggcaa
     4801 agagaaggcg tagaagctgc gaaacaaaag ggtgtaaaat tcggcagaaa gaaaattgct
     4861 ttacctcctg aatttcctgc gatctattct gactggaaag caggaaagat aactgcagtc
     4921 tatgctatgg atcaattggg catgaaacga aatacctttt atcgacgggt gaaagaatat
     4981 gaacatacct tgcaccactt ttcttgatag atataacagc tattagacgg gaagggagag
     5041 tttgaaaatg gacttaacga atcaaagggt cgtttttact ggaacgctgc agcaaatgac
     5101 acgaacccaa gccatcggtt tggttcactc tttaaacggc cattgtcaat caagtgttac
     5161 ttcaaaaaca aatttcctgg tttgtggtca gtattctaag tcgttgtttg atgattctct
     5221 ctatacaaaa aaggaacaaa ccgcgcggga cttgattgcg ttaggtcatg agattaccat
     5281 tttatcagaa gtcgaatttt atgcgttaat tagtcaacag ttgaaagaat ggcaacggta
     5341 tttataatcg ttagtaaaat ttacaaggag gaaaattttt atgaagcgaa aatcttatga
     5401 tcgttggggc attgaaataa ctagttttaa tcgaaatatt gcttttcacg tggagtgtga
     5461 ctgtggggaa ttagcaaaaa gtgtttatca aaaaaattac ttttactgtc ctaaatgcca
     5521 tcgccgatac ggggtacatg gaacatagaa acgaaatagt gcggtagaaa agcgaatgaa
     5581 tgtagtatat ttctacaaat cattcgcttt ctttatttta taaatagttg gtcgagagat
     5641 cccgttttct tttgcaatct ctgcaactgg aatgccttgc tttaacatgt ccaccacggt
     5701 tttaaaaact aagcgttttt gcggatctgt tgagttaata gaatactcga ttggtcgtcc
     5761 cttatatcgg ccggcttttt gagccaataa tactccttgc cgctgacgtt cacgaatttt
     5821 ctcacgctcg ttttgtgcaa tataacttag cagtgataaa aacatatcga acatagcggt
     5881 atccaggagt tcatttccag tattaaaatc taaaaactgt gcatctaata tttttaacgc
     5941 tacttttttc tgtttcataa aagcaactgt attttttata tcttcataat ctcttcctaa
     6001 acgatctagt gatgggttct gttgcgaagt ttgaaaatca aacgcgccct ctctgaactc
     6061 caaatatctt aggctgtta
//
LOCUS       DBGZHO010000099         5727 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.104, whole genome shotgun sequence.
ACCESSION   DBGZHO010000099 DBGZHO010000000
VERSION     DBGZHO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.104"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            196..921
                     /locus_tag="ACN3HL_002675"
     CDS             196..921
                     /locus_tag="ACN3HL_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007469.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACN3HL_002676"
     CDS             911..1420
                     /locus_tag="ACN3HL_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007470.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACN3HL_002677"
     CDS             complement(1490..2938)
                     /locus_tag="ACN3HL_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HHC8007471.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACN3HL_002678"
     CDS             complement(2938..3654)
                     /locus_tag="ACN3HL_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HHC8007472.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLAAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACN3HL_002679"
     CDS             complement(3635..3985)
                     /locus_tag="ACN3HL_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HHC8007473.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACN3HL_002680"
     CDS             4129..4902
                     /locus_tag="ACN3HL_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HHC8007474.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACN3HL_002681"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACN3HL_002681"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1124 c          995 g         1946 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 agcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DBGZHO010000100         5689 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.105, whole genome shotgun sequence.
ACCESSION   DBGZHO010000100 DBGZHO010000000
VERSION     DBGZHO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.105"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(488..1297)
                     /locus_tag="ACN3HL_002682"
     CDS             complement(488..1297)
                     /locus_tag="ACN3HL_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HHC8007475.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACN3HL_002683"
     CDS             complement(1297..2043)
                     /locus_tag="ACN3HL_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HHC8007476.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACN3HL_002684"
     CDS             complement(2061..2528)
                     /locus_tag="ACN3HL_002684"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HHC8007477.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACN3HL_002685"
     CDS             complement(2528..2938)
                     /locus_tag="ACN3HL_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HHC8007478.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACN3HL_002686"
     CDS             complement(2949..3962)
                     /locus_tag="ACN3HL_002686"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8007479.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACN3HL_002687"
     CDS             4179..4913
                     /locus_tag="ACN3HL_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007480.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACN3HL_002688"
     CDS             4897..5607
                     /locus_tag="ACN3HL_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007481.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DBGZHO010000101         5598 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.106, whole genome shotgun sequence.
ACCESSION   DBGZHO010000101 DBGZHO010000000
VERSION     DBGZHO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.106"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            101..430
                     /locus_tag="ACN3HL_002689"
     CDS             101..430
                     /locus_tag="ACN3HL_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHC8007482.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(717..1202)
                     /gene="vanZ-A"
                     /locus_tag="ACN3HL_002690"
     CDS             complement(717..1202)
                     /gene="vanZ-A"
                     /locus_tag="ACN3HL_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HHC8007483.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(1355..2266)
                     /gene="vanY"
                     /locus_tag="ACN3HL_002691"
     CDS             complement(1355..2266)
                     /gene="vanY"
                     /locus_tag="ACN3HL_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HHC8007484.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(2694..3302)
                     /locus_tag="ACN3HL_002692"
     CDS             complement(2694..3302)
                     /locus_tag="ACN3HL_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HHC8007485.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(3308..4339)
                     /gene="vanA"
                     /locus_tag="ACN3HL_002693"
     CDS             complement(3308..4339)
                     /gene="vanA"
                     /locus_tag="ACN3HL_002693"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HHC8007486.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(4332..5300)
                     /locus_tag="ACN3HL_002694"
     CDS             complement(4332..5300)
                     /locus_tag="ACN3HL_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HHC8007487.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         1645 a         1202 c          965 g         1786 t
ORIGIN      
        1 attgcttata atagtgtatt ggaattaagg tagattgaca aaagagtgat caaataggta
       61 tacttcattc aaataatcgt ttgaatgtga ggtgagatga atgaaaaaag tttgccaagt
      121 gactgtcgta cataaagaaa aagtaaatgg aataaaaaat aaattggatc aaaaagattt
      181 ttcaaactta cttgtgttag ggaaatgttt cagcgatttt tctagaatta aaattttcta
      241 tgctttagaa acctataagg aaatgtgcgt ctgtgattta gcagaaatac ttactgctag
      301 tgtcgctaca acgtcacacc atttacgttt tttaaaaaaa catggaatgg caaaatcacg
      361 tcaagatgga aaagtagttt attactcttt agcgaatgaa gacatccttt ccgctattcg
      421 tgttttttaa agttatcaga aaatctatct atgaaatctt agtttggggg taccgtcagg
      481 aaaatgcgga tttacaacgt taaggaaatt tattaaagag accaattcct cagcactaaa
      541 attgataatt gggctttctt tgttactata gtgttaggta agctttttac tttatcaccg
      601 gttttcccct cacttcacac ctacgggcga gtttccccac atcccgtttt ccatctaatc
      661 caattcattc aatatcttta tgtgtatgaa agatcagatt gcttgattta gacatcttac
      721 acgtaattta ttcttaaatg ggtacggtaa acgagcaata atacgagcaa aagtatacct
      781 acaaaaataa taactctgtc taattttttt tgattcatat gcttattgct taaaccatat
      841 aatttcagtc caagaaagcc tccaacagta tttgtaatta catctgttat gtctgtcgct
      901 ccaatagcga agataaattg aattatttca aaagtaagac ttaaaaccag tacaaaagca
      961 aacttaggta aaaatccgat ttctttaaaa ttgacattca aaagcaagcc aaatggaata
     1021 aagattataa cattatctat catctctctg aaattcccag tagcagtaaa tggagtcaag
     1081 ttaagacttc tttgatgata attaaatact gataaaatat tgtattgtaa tttgaataac
     1141 actaaccaga ttagtgtcac taaatataaa gctagcaatc ctctagataa tatttttccc
     1201 aatataattt cctctaattc ttttgtttaa gttgtatcat tagtatagca atgtcctagt
     1261 taacgtgggt tttaaattaa aaagctaacg ttaccccaaa agtgctagta caataatgct
     1321 gttcattaat ttcgttggtt tcattccgcc atccttacct ccttgaatta gtatgtgttg
     1381 atccgggaaa cactgtcaca attacaccgt ctatattgtt tcctgatatc tcataacgaa
     1441 gattagtcgg cacatgaatg gtggtatttt tagtaacagg ataataaaag atctcatatt
     1501 tttccccatt tacactaaca gaaatggttt tttcttcttt taggtaatcc atatattcct
     1561 cgagaacgaa attcttttct ttcataatcg cactatgtgg taaaccaaca tagcgaatat
     1621 gccatagttc atattgaatt cctgttaact ctgttttgtc ctctggataa cgtaaaatga
     1681 acccgtattt ccaagcattt tcttctatcc actttccttc aggggctcgt tccattttcg
     1741 tcaagcttga tcctacatct agtgataaac ctgaattatg ctcactataa cctgctggta
     1801 aggcatactc agcccccatt tcttggtaaa gcacactttg ctcatcaaag tctcgatagc
     1861 cactattaat aataaaatga ctaacgccac cctttacagc atcattgacc atctctgaaa
     1921 atttttgtgc tatttctttt gacatataaa tattactatc aagcaacccg tatccattta
     1981 ttaattcgtc atgtttagat aaattcacga tatctgactt cacactttct tggcgaacag
     2041 gatatttact attgattaat agcagatttc cttgataaac ctgttcttct gtaattgttt
     2101 tctcttgggt attttcagaa gtcccactat tttctaaatg ttctttggga ttttgatcat
     2161 aattttgaaa ttcgactttt tcctgagaaa acagtgcttc attaacgtag tcataaccta
     2221 agtatattaa gaataacaat aacaataaaa aaaacaactt cttcattttc agtctcctcc
     2281 ttaactatat agttggaagt atgaaatatt tctagaatct tccccttaaa cggcacaatc
     2341 tcgtttgaga ttgtgccgtt ttgccccgta aattacagtc aattatttcg ccctactgga
     2401 tttactatta tcaccaatgt agatgaattt tcataagtga tacccatgct gaatttaacg
     2461 aggctgaact gcctgttgac aatgggcggt gtgaaatacc acccctctat gcgatcagtc
     2521 ttattatcag gctatcttgc cgcagcgcac gcagataatg accgcaatat cgctctgcct
     2581 tacatcttca atactatcta ctatatataa attccctaag aaccagttac atacgtcggg
     2641 tttcctgccg aaagagttag cttatatagt ttgtccgtgc aacggttaaa agtttattta
     2701 acggggaaat caaaatagct attggggtat ggttcgtctc ttaatacata gtgccaccat
     2761 tcgaggctat atgcttcaaa cccactgttt tccatgatgg agcgcaaacg tctgcgattt
     2821 tgcgcttcat tgcatgatat tccatttgcc gcatgatgag agcgttcatc cataaaatca
     2881 aatcggctcc ccattggtac aagctcaccc gtgtctaatc gataaagcgt aagatcaatg
     2941 gcactgccgc ggctatggct tgattttgaa gccacgtatc cttttgaaat catctcagtt
     3001 cggtcaatat tgggataata actttccttt gtcaggttat tttccggctg tgcagcccat
     3061 tgcataaaac agtttacagc acgattagga cggtaaccgt cccatagaag caatccgtac
     3121 ccttgggtag cagccagttc ttttgccttc aaaagcgatt cagccaactc gtatgtccct
     3181 acaatgcgat ttacttcata accgtcaacc ggttttccgg tgaaattatc ccaagtggca
     3241 tatttagcgt cccaacgaac accgtgtact atttcatcta aaaaagtaaa tcctatttcc
     3301 atgcttatca cccctttaac gctaatacga tcaagcggtc aatcagttcg ggaagtgcaa
     3361 tacctgcagc ggccatcata cggggataac gactgtatga cgtgaaaccg ggcagagtat
     3421 tgacttcgtt cagtacaatg cggccgttat cttgtaaaaa catatccaca cgggctagac
     3481 ctctacagcc gagcgcttta tatatttttt ttgccgtttc ctgtatccgt cctcgctcct
     3541 ctgctgaaag gtctgcggga acggttataa ctgcgttttc agagcctttt tccggctcga
     3601 cttcctgatg aatacgaaag attccgtact gcagcctgat ttggtccacc tcgccaacag
     3661 ctaacgcggc actgtttccc aataccgcac aaccgacctc acagcccgaa acagcctgct
     3721 caattaagat tttgctgtca tattgtcttg ccgattcaat tgcgtagtcc aattcgtccg
     3781 cgctattgac ttttttcaca ccgaaggatg agcctgaacg cgccggctta acaaaaacag
     3841 gataggtaaa cgtagctgcc accggcctat catctttatt aataacccaa aaggcgggag
     3901 tagctatccc agcatttttc gcaacgatgt atgtcaacga tttgtccata caaattgctg
     3961 agctttgaat atcgcagcct acaaaaggga taccggacaa ttcaaacaga ccttgtatgg
     4021 atccatcttc acctgacttg ccatgcaaag ctgaaaatgc tacatcaaca tggttgattt
     4081 catattcatg gttcttttta acaagtaatc cgtgcatttt tttatccggc gagagtacag
     4141 ctgaatagca attgtcgttt tcccattccg cgcaaggttt ttcgcacatt ttccatacac
     4201 cagatttcgt aattccaatg tataacggct cgtatttttc tttattaatg ttagcggcta
     4261 tctctattgc agattttacc gatacgtcat gctcctctga gcaaccccca aacagtattg
     4321 caacttttat tctattcatg ctcctgtctc ctttcaaaat ccaaacagtt tttaatggtt
     4381 ttttcaacgg tatcacgcaa cgcttgctcg gtataatagg ccgtatgcgg tgtgattatc
     4441 acgttaggca ttctttgaag tttaagtaaa aattgattat caattggttt ttgggtgcaa
     4501 tcagagtaga aaaactcttc ctctccttcc aatacatcca atgcggcacc gcccagtttc
     4561 ccgttttcta atgctttaac caactcatag gtatctacaa gtggaccgcg cccagtattg
     4621 ataagaaatg ctccttgctt cattctctgt atttgttcgt ggctgataat atagtgcgta
     4681 tccgtattga gcggcacatg aagcgtaacg atatcgctat tttgcagcaa ctcatcaaac
     4741 ggtacatagt ttacctctat acttcggctg cgactataag ccaacacttt acatccaaat
     4801 cctcgcagcc gctcaataac cgctttgcct atctggcccg ttcccaccac accaactgtc
     4861 atgtcgctga gtaccttgcc acggtcgctg tccaacctga aatcatgttt ttccacagag
     4921 cgcacaatcg attttacgtt gcgtactgcc ataagaatta gcatcatagt ataatcggca
     4981 acgctatccg gcgagtacgc cacattgtcg acagtgatgc ccattctctt agcagcagtt
     5041 gtatctatat gattgcagcc gatgcttcgg gtagaaatat atttcacacc ggctctcttc
     5101 agcgcaagaa gaatagaggc ggaaatctct gatttatgtc ccacactgat acattgattg
     5161 aaaggcgcgg atttggcgtt ggattccgac acgttggcgt taattatcgt tgccataacg
     5221 ccaaagcgag gcgaaagagc atggaatgca tctgcctcat cctgctcaca tccataaaca
     5281 gtaatgccga tgttattcat aattaagacc aaccctttct gtgaaaggca ccaaataaaa
     5341 cggggatgcc aatggtaatc ttgtcaaatc tttctctgaa gaacgaaaac ggctcgttct
     5401 tacggtatta agtctaccgt gtaagaacga gccgtttctt aatattaaat tgttaatttc
     5461 ctaagaaaaa gtaaagataa ccttgagatt ttcctaaaaa attatggctc tatacttttt
     5521 gatgttggtg gatgacacca gcatcttttt tattttccaa aacatataga aaagacacct
     5581 tgaaatcctt tagaatta
//
LOCUS       DBGZHO010000102         5560 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.108, whole genome shotgun sequence.
ACCESSION   DBGZHO010000102 DBGZHO010000000
VERSION     DBGZHO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.108"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            181..495
                     /locus_tag="ACN3HL_002695"
     CDS             181..495
                     /locus_tag="ACN3HL_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8007488.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            516..893
                     /locus_tag="ACN3HL_002696"
     CDS             516..893
                     /locus_tag="ACN3HL_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HHC8007489.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            903..1676
                     /locus_tag="ACN3HL_002697"
     CDS             903..1676
                     /locus_tag="ACN3HL_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007490.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            1698..3101
                     /locus_tag="ACN3HL_002698"
     CDS             1698..3101
                     /locus_tag="ACN3HL_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HHC8007491.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            3283..4467
                     /gene="mobT"
                     /locus_tag="ACN3HL_002699"
     CDS             3283..4467
                     /gene="mobT"
                     /locus_tag="ACN3HL_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HHC8007492.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            4464..4754
                     /locus_tag="ACN3HL_002700"
     CDS             4464..4754
                     /locus_tag="ACN3HL_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007493.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            4751..4972
                     /locus_tag="ACN3HL_002701"
     CDS             4751..4972
                     /locus_tag="ACN3HL_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007494.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            5014..>5560
                     /locus_tag="ACN3HL_002702"
     CDS             5014..>5560
                     /locus_tag="ACN3HL_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007495.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKL"
BASE COUNT         1880 a          941 c         1101 g         1638 t
ORIGIN      
        1 ttttaaatat agtaggaatc ggacgctcag tacggagcgt ctattttttt acccaatttt
       61 gaaaggaagt gaacttatga aaataaaaaa tcaagaatca aaaggtcgct ctcccccctt
      121 taaaaccatc acacaaataa gattcattca aacataaaaa cagaaaggat aggtaaaaat
      181 atggaactta aatatgtcat tcccaatatg gaaaaaacat ttggacaatt agaatatgct
      241 ggtgaaggga acattgaaca acgtcgaata aatggcagac caaccattct ctctcgtagt
      301 tacaatttat actcaacgat tcaacgagca gatgatattg ttgtcattct tccctccgaa
      361 gctggcgaga aacattttga atccgacgaa aaagtcaaac tcatcaaccc acatattacc
      421 gcagaaggtt ataaaattgg caatcgagga tttaccaatt acattatgca cgcagacgat
      481 atggtgaaag cataagaaag gaaaggtgaa aaaatatgag attagcagaa ggtattgtga
      541 ttgaaaaaga ccagacattt ggcacattga aattttccgc cttgcgtcgt gaggttcgta
      601 tccagaatga agatggtacg gtttccgaag aaattaaaga acgtacctat gacttaaaat
      661 caaaaggaca aggacgcatg atacaagtca gtatccccgc ttctgttcct ttgaaagaat
      721 ttgactacaa cgcagaagtg gaattaatca atcctgtggc agataccgta gcgacggcta
      781 cttttcgagg ggcagacgtt gattggtacg tgaaagcaga cgatcttgta ttaaaaggac
      841 agacaaaacc tcatcagaaa tataaaaaag aagcgtccga aagtgaaaaa taggtgttgc
      901 ttatgacaaa cacaccattg attttgaaag aaattccgaa ggatgaagcc atttctttta
      961 ttcggcaata ccattattca aagatactcc ctagattgtg taaatacttt ctagggattt
     1021 tttcagaaga aaaattatta ggcgttgtgg aattaggctg gggtacgcaa cccctacaaa
     1081 ccatacgcaa actctttccc gacagttccc ttcaaaccac agattattta gaaattggaa
     1141 agatgtgttt tcttccagaa atgaatcaaa ccaattattt tggcagtcaa gctctttcag
     1201 ctctaattaa gtggttgaaa gaacatacgg actgtcattt tttatataca ctggcagatg
     1261 gaattgaggg aaaatgtggc tatgtctatc aagcgtccaa cttcttttac tgcgggtatt
     1321 tcaagacaag tgtctatcgt gataagcagt catgggaaaa gatacaccct cgaagtgctc
     1381 gccttttatt agaggaaaat gctcgctttg aacaggtaga gaaaaagcat tggctttccc
     1441 aggcattttg cgaatacaaa gggattgaga aaatcaatgg acgcatgttt cgctatctct
     1501 atccgttgac aaaagaagcg aaaaaactgt taggacacac tctctatcga cgtcattatt
     1561 atccgaaaga aaaaaattta cgctttgaaa agcgaatcgc ttatcagaaa tatgaagcca
     1621 tttctcaacc aacttttgat aaacaggctc gtatctacaa tacacaatta ttttgatagg
     1681 tggaaaggag gatttttatg ccattgcttc atgacagagg agagcgaatc aaagccaacg
     1741 ataagcactt ggtctatcat tttgtactaa tttcattgct ggtagttttt ctagtcgtcc
     1801 tactcccttt tcattggaga gcgttacaat cggtgaactg gcaagcagtt cagttagata
     1861 catttttcta tcaacttcat acgccatact tttggagcag tattctcact gctctttttg
     1921 tatgcggact tatcagctgg ctttattatc actatcgtat agattctata aaacagttag
     1981 agcaccgtca aaagttagct cgtatgattt tagaaaatca ttggtatgaa gccgaagaaa
     2041 ctcaatcaga gggattcttt aaagatttac ccagcaagaa aaccaaacaa cgaatccgcc
     2101 attttcctaa aatatattat cgaatgaaag atggactaat ccatattcat gtagaaatca
     2161 ccttagggaa atatcaagat cagcttttgc acctagaaaa caaactagaa acaggattgt
     2221 attgtgaatt agtggaaaaa acgttgaaag attcttatgt agagtatgtc ctactttatg
     2281 atactattgg caatcgaatt ggcattgaag acgtggtagc tcaagatgga cgtgtcaaat
     2341 tgatggaatc ggtctattgg gagttcgatt ctctccctca catgttaatt gctgggggca
     2401 ctggtagtgg aaaatcctat tttattctca cattgattga atctctcctg catacaaatg
     2461 caaagcttta tattcttgac cctaaaaatg ctgatttggc agacttaggg gcggtcatga
     2521 ataatgtcta ttaccgtaaa gaagatatgt tggcatgtat caatcaattt tacgaagata
     2581 tgattgatcg cagtgaaacc atgaaacaac accctaacta taaaacagga gaaaattatg
     2641 cttatcttgg tttgtctgcc aattttctta tttttgatga atatgtggca atgatggata
     2701 tgctaggtcg tgaaagtacc accgttattc ataaactcaa acaaattgta atgttaggac
     2761 gacaagcagg cttcttttta attcttgcct gtcaacgtcc agacgcaaaa tattttagtg
     2821 atgggattcg ggacaacttt aacttccgtg tggctttggg tcgtatgtct gaaatgggct
     2881 ttggtatgat gttcggaagc gatacacaaa aacaattttt cttaaaaccc atcaagggaa
     2941 gaggttacgt ggatacagga aaaagtgtga ttagtgagtt ttatacaccc cttgtaccaa
     3001 aaaggtacga tttcttagga gaaataggaa aagtcattca aaaaaagcaa tctgagcctg
     3061 taccgcacga agtgaaaggt acaggttcag acttgctttg attggtgtgg cgttagccac
     3121 gccaatcctt tagccccctc tatctaacag gggggcacaa atacaactga aaacaggcaa
     3181 ttctcatcaa ccaatgttga tggtacaaag gattgcggaa aatatgaaag gtgtaaactc
     3241 aagggtcata gtttacatct tttttagatt ggaggtttgc gaatggaaaa cgaaaaaatt
     3301 tggattaagg aattgaaaga aaagcgactg gcttatggcg tttctcaaaa taaactggcg
     3361 gttgcttctc atattaccag accttaccta tcggatattg aaacaggcaa ggcagtccct
     3421 actcaacagg tgaaagaaga tttactgaac gctttggaac gcttcaatcc cgataaccca
     3481 ttggagatgt tattcgacta tgtacggatt cgattcccta ccaatgatgt ggctcaaatt
     3541 atcggtgagg ttttacgttt gaatatggat tatatgctac acgaagactt tggctattat
     3601 tcttatcccg aacactatcg tttcggtgat attgttgtcc tagtctctca tgatgtaagt
     3661 aaaggtgttt tattagaact gaaaggaaaa ggctgtcggc aatttgaaaa ctttctattg
     3721 gctcaacatc ggagctggta tgatttcttt caagattgca tggaacataa aggtattttc
     3781 aaacgcttgg atttagctat caacgataaa acagggattt tgaatattcc agatttggca
     3841 aagaaatgta aacaggaaga atgcatttcc gtctttcgaa gctttaaaaa ttatcgcagt
     3901 ggtgaattgg ttcaccgtga tgaaaaacca tacatgggaa acacacttta tattggctca
     3961 ttaaaaagtg aagtctattt ctgtatatat gagaaagatt atgagcaata cgtgaaaaat
     4021 gatgttccct tagaagacgc agaagtaaag aatcggtttg aaattcggtt aaaaaatgac
     4081 cgagccaccc aagccatgaa agatttattg gcacatcaac aggcggaaaa aacagccttt
     4141 gaaattatca atcgctatat ccgctttgca gataaagacg acactaaacg tcggagtgat
     4201 tggaaaacta atgaacgttg ggaatggttt atcggtaaaa atcgtggagc attacgccta
     4261 accacacagc cagagcctta ttcttttgaa cgaacattga actggttaca tcatcaagtc
     4321 gcccctacat taaaaatcgc aagcatttta gatgttctca acggtacaac cattatctcc
     4381 accatgattc aggaagccaa actgacagaa aaacatgaga aattaattga acaacaacat
     4441 ctagccatgg aggatttgat tacatgagcc ttttaacaaa agaattaaag aagttagggt
     4501 ttcagtgtgg cattgagttt caagcgtata tacaaaatac agggaaatat acgtctctca
     4561 ttattgaggg aaaacggcaa gctggtgata ccatctatac ctatgatttt tacaaggtga
     4621 gattttataa taattatacc aatcgagtaa ccgtctatgg agagcattta accccttttc
     4681 aattattaag gcgtgtaaaa agctatatct attatcgaga aaaatatctt aaggaaagga
     4741 ggacaatcac atgaattttg ggcagaattt gtacaactgg ttcttggata atgcacagtc
     4801 attggtattg ttagcgattg ttgtcattgg actgttttta ggttttaaac gagaattttc
     4861 aaaactcatt ggcttcttga ttattgctct aatcgccgtc ggacttgtgt tcaatgcagc
     4921 tggcgtgaaa gatgtgttat taaacttatt taaccgaatc attggtgctt aacagatatt
     4981 tttcatgata aaataggaag tatatatttt gttatgaaag gatttatgaa tatgtttaca
     5041 aatgatcaat ttaaatctct tttaattaaa acattagaaa gaaagagctc ttcaaattat
     5101 tatgaaggag gtaacgagat tgtttctaaa atgaaaatat cagaggtaac tttagatgag
     5161 actgacgatt ttacttatta taaaggatat aaaaagggct ggaatacgct ttgcacatat
     5221 cttaaaataa gagttccttt tgatgattta gacttttttg aaagtcataa agatttgatt
     5281 acccagacag caagctccat atatgataaa caaggtgata atgtattagt ggatactatt
     5341 ttagtaccac ttccagagaa ttacgaagta attaacttta gtcagttgaa aattagtgat
     5401 gtggtttcac aagctattga agacgctgag tcttttatga gtaatggtga atatcaacgt
     5461 gcctttgaca gagttcacac tgcttttcat ggatatttaa ttgaaatact aaaaaaatat
     5521 gaaattacag ttcctagaga cgaaaatcta tctaaattat
//
LOCUS       DBGZHO010000103         5296 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.109, whole genome shotgun sequence.
ACCESSION   DBGZHO010000103 DBGZHO010000000
VERSION     DBGZHO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.109"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(55..1203)
                     /gene="nagA"
                     /locus_tag="ACN3HL_002703"
     CDS             complement(55..1203)
                     /gene="nagA"
                     /locus_tag="ACN3HL_002703"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HHC8007496.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1279..2115)
                     /locus_tag="ACN3HL_002704"
     CDS             complement(1279..2115)
                     /locus_tag="ACN3HL_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007497.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2299..3516)
                     /locus_tag="ACN3HL_002705"
     CDS             complement(2299..3516)
                     /locus_tag="ACN3HL_002705"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HHC8007498.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3665..3826)
                     /locus_tag="ACN3HL_002706"
     CDS             complement(3665..3826)
                     /locus_tag="ACN3HL_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007499.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3899..3982
                     /locus_tag="ACN3HL_002707"
     tRNA            3899..3982
                     /locus_tag="ACN3HL_002707"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3933..3935,aa:Leu,seq:gag)
     gene            complement(4222..>5296)
                     /locus_tag="ACN3HL_002708"
     CDS             complement(4222..>5296)
                     /locus_tag="ACN3HL_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007500.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVN
                     GNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKT
                     SIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQK
                     NEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1646 a         1080 c          837 g         1733 t
ORIGIN      
        1 aaaaccttaa aaccaaactt aagaagttta gttttaaggt taacttaaat tatattatgc
       61 gtggaaacgt tccacgccat ctagataagt tgcttccaat gtcatatcag ggttcaatac
      121 gataaagtct gcatcgcgtc cttgagcgat ttttccacat gtatcatcga ttttacagct
      181 gattgctgga atcagactag ccatcatgac tgcttgttct ggtgttgcta atccccagtc
      241 tacaacattt ttaattgctt ctttcaattt caatatactt ccagctaagt tgccagattc
      301 tagacgtgct gttccttctt ttactactac tggaaattcg cctaaattgt aatttccatc
      361 aggcatccca ccggccatca tacagtctgt aattaatgcg acatgatcat gtcctgcttt
      421 ttccattagg attcccgcag catttggatg tacatgatgg ccatcacaaa tcaattcaga
      481 aaagacatgt tctaaagata ataacgcacc caccatacct ggttcgcgat gattcaatcc
      541 acgcatacca ttgaaagcat ggacaaatac acttgcgcct gcttcaacag ctttttgcgc
      601 ttcttctagt gtagcattac tgtgtcctag agaaacaact actccttctt cagtcacttg
      661 tttgacaaac tcttctacac cttgacgttc cggtgctaaa gcaatttttt tgattaaacc
      721 acctgaagct tcttgccatt catggaaagt atccaaatca ggatccccga aataacttgg
      781 gttttgtgcc cctttgtgtt cttctgtgaa gaaaggacct tcaaaataga ttcctttgat
      841 tttagctcct ggtgcttcct gatacatttt gccgattgtc tcagctacat cttttaaacg
      901 ttctttgctt gacgtcaatg ttgttggtaa aaatgaagtc actccacaag ataacagacc
      961 ttcagacatc actttgatgc cttctgcatc attatccatt acatcatgat tcatatagcc
     1021 gtgaatatgt gtatctacca aaccaggagc aatccatttg ccgctttggt caatgatgtt
     1081 gacttctccc tcaggtagtt ctttggtgta ttcaccaaaa agtccatcgg taatttcaag
     1141 atagcctgca tgtttgacac ctgacgctaa aaagaatttg tcagcataga taaaagttct
     1201 cattctattc tctccctttg tttttctacc tctaaagtac tcttatttag agaagaagtc
     1261 aagaatggtc tacaccattt acaaattttt tgaaatttgt ttcacagctt gtgctaagcc
     1321 ttcatagaat gctgctcttt ctggttcttc tttacgcttg tatattaagc ttttaagcac
     1381 aaataaatca ttgaggtaat agtagctatt cttctcttga gcccaataga ttccttgatt
     1441 cacctgttct aacgcttcgt cgatttcatt ttgatggaat aagaaatttc cataattata
     1501 aaaaatttgc gaaaattcac tttttgatcg ttcatcagct gattgatgca gcagttggat
     1561 gcttcgactc aaatagtagc gtgcttcagc cgtttttcct gccacaccat atatttttcc
     1621 gatacaacta atcagttgta tttctgtgtc agaaacatgg attctttctt tttggctaga
     1681 gtagcttaat gcttctttca aataataaag ggactgagag atattttgac gcaacgtgaa
     1741 ttcgcaaaca ccgagataat aataatagcg ttgaaagtca gttgcttgat acagattttc
     1801 agaaatatca gaagatttta gtacttgttc taacttccga taatcacgtt tttggaaaca
     1861 actatccaac agttcaaata atttatcgtt tgtccgagta gtttttcgag agagattcat
     1921 cacatgatca atcgttaccc ctagccgttg acaaatctgc atcatcacca atacattcgg
     1981 cagttcctca ttattttcga tccgacttaa tacactttgt gaacaaatat catgcgaaag
     2041 cattttttgc gtcatttttt gttcttttcg aatctcttta atgatcgttc caaaggactc
     2101 gattaacgtt tccataagta tcctccccaa aatatgcgta ttcgcattct attcgtattt
     2161 tactttagga agtcgcaaac ttcaagaaaa gacttgcaac taaataatat actttagtta
     2221 tttaagaaaa ctccactaga aagagagcct cagtgtgttt gtctgtggcc ctcctactga
     2281 aaaatttggt ttttaaaatc atttttggcg ataggttgct aggaattctc tcattttctt
     2341 agctgtttgt ttcaaatcat ccattttagg aagataaacg attcgaaaat gatctggctg
     2401 gttccaatta aatccaccac catgtacaag tagaatatga tgttcatgta aaaagtccaa
     2461 aacgaatttt tcatcatcca aaatattgaa tcgctttgta tcaatttttg ggaatatata
     2521 aaaagcagct tttggtttta cggctgaaag accaggaata tcattgattg cattatagat
     2581 atattctctt tgttcataga tccttccgcc tggcaggagc agctcatcga cactttgata
     2641 accgcctagc gcggtttgga taatttgctg agacaataca ttggaacaca aacgcatgga
     2701 ggacaacata ttcagccctt ctatatagcc tttgacgtgt gacttatctc cacttaggac
     2761 catccagcct actcgaaatc ctgctacacg atgagatttg gatagaccgt tcagcgtaac
     2821 aacgaacaaa tcaggcgcta atgtagcaat cggaatatgt tctagaccat ccatcactaa
     2881 gcgatcatag atttcgtcgg aataaataat caggttattt tgtcgagcta cttcaacgat
     2941 ttcttctaat aattcttttg gataaagtgc cccagtagga ttattaggat taatgataac
     3001 aatagctttt gtccgactcg ttatttttga tttgatatca tcaatatcag gataccattc
     3061 tgcctcttca tcgcaaatat aatgaacagg tgtgcctcca gctaatgcaa tagaagccgt
     3121 ccacaacgga tagtccggca ttggaaccag tacttcatct ccattgtcca gcaacccctg
     3181 catacacatc gtgatcaatt cgctcactcc gttgccggtg tagatatcat tgatcgtcac
     3241 attcggaaaa tgtttcagtt ggcaatattg ctcaattgct tttctagcag aaaagatccc
     3301 cttggaatct gagtagcctt ctgagtcacg ggcattcatg atcaaatcac gaatgacttc
     3361 gtttggtgct tcaaatccaa aaggtgcggg atttcccgtg ttcaatttta aaatactaat
     3421 gccctcttct tgcatccgct ccgcttcttc tagaacggga ccgcgaacat cgtaactgac
     3481 accttctaat ttgttggatt tttcaaattc tctcatcact tagccaatcc ctcatttcaa
     3541 aaagttagaa ctttccaaat tttttgttat ttactatttc aatatcatac tccatcctag
     3601 aaaattttgc cacttattta ggaaaaacgt aagtattaaa aaaacacaaa caagcgttga
     3661 gaacttaatt gtcatgatag tcattccata gattcgctgc ccaatccatt gcaattccac
     3721 aaatgattcc tagcataaaa ccaagcaaaa aacgtccgaa tgcaagtcca atcaatacac
     3781 ctaagatcat tcccagtcct gaaaattctc cgtcatattt ctccatctta ataagtcctc
     3841 ccatttttga gcttgacaac tatgtaaaac ctcgctatca ttagtgtgtt attattacgc
     3901 agatgtgttg gaattggcag acaagcatga ttgagggtca tgtgagcgtt agctcgtgtg
     3961 ggttcgagtc ccatcatctg cactacaact cgtgaagtta attttgcttc acgagttttt
     4021 ttgtttgaac gtttctttat gccattatat acatatcact gtatccttta caaaaagaac
     4081 gtacaatcat gtaaacagcc tgaggtgagt atatgaaggt cggaaacaag ctactcgtag
     4141 aaacttgcaa gtgttaaaac aattaatcga aaaacgagta aaatccctca cctaatacta
     4201 aagcgaggga ttttttgtat attatctgtt tatcaccgtt attataaagg tacaaatacc
     4261 aagcacggtt aatccaaatt gcataaattc atttttttgt acactcatgc ttttcattag
     4321 ctctttaact gccattagta ctaagatggc gataacaaca taaagtatat agtacgtccg
     4381 cattccggaa gcccatactg tgggagaaaa tcccataatt aaccttgaac aaaatcccat
     4441 tatcatcaaa ataactaaaa aaatagaagt tttcttattg tcaaaactta aataaattcc
     4501 aacaattaaa catagtaata atgccaagac tactaaagta gctatccaag tacctggata
     4561 aaaaagtgac agtttcgttc ctaactctgt aaagagatta ttcaggttac tactactcca
     4621 aatcattgcc cttttatttc cattgacgta agtaaagctt tgacccattg tattaccaaa
     4681 ataaataatc aggtttaaga aaaacggtaa tgcagtcaat atacgcacat aatagttttg
     4741 acatttccta tatgttagaa ggaaaattaa gaaaaatagc aataaaaata agatattcat
     4801 gtctaaaaaa aacggctttc caaatgatga aatacctaaa tctaacttat taagaaagtt
     4861 gaaattttta tattcaggaa accatttatt aatttcatgt gcagcacgta atgcattccc
     4921 tggagttgtc aaagagaaaa ttaattctgc taagcttatt attgaaaata ctgataactt
     4981 ataattatat cgtccattga caatcaaata taaactaact atacttgtta gaacaaaaaa
     5041 acaggcgttg acttgttctt gattagttaa aaatatcaat aaaggaatac ttacccaata
     5101 tatttttcta tttatttctt ctcctcttaa gagttgaaaa aacggataaa aagttagtaa
     5161 actaaatgct actggccact gatagttcaa ggtggttgct ctccaaccgg tttcccccat
     5221 tactgtcaat ggtattaaac agtatataga gcaaaccaat aataaatttt taacatttat
     5281 tttctcaaaa acatac
//
LOCUS       DBGZHO010000104         5198 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.110, whole genome shotgun sequence.
ACCESSION   DBGZHO010000104 DBGZHO010000000
VERSION     DBGZHO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.110"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            24..695
                     /locus_tag="ACN3HL_002709"
     CDS             24..695
                     /locus_tag="ACN3HL_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHC8007501.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            754..1194
                     /locus_tag="ACN3HL_002710"
     CDS             754..1194
                     /locus_tag="ACN3HL_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007502.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1206..1874
                     /locus_tag="ACN3HL_002711"
     CDS             1206..1874
                     /locus_tag="ACN3HL_002711"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HHC8007503.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1938..2561
                     /locus_tag="ACN3HL_002712"
     CDS             1938..2561
                     /locus_tag="ACN3HL_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HHC8007504.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2617..3003
                     /locus_tag="ACN3HL_002713"
     CDS             2617..3003
                     /locus_tag="ACN3HL_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HHC8007505.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3216..4607
                     /locus_tag="ACN3HL_002714"
     CDS             3216..4607
                     /locus_tag="ACN3HL_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HHC8007506.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1727 a          861 c         1095 g         1515 t
ORIGIN      
        1 atgatgaaaa aagggggaga aaaatgaatt ttttagttgt tttaaaagat actctgattg
       61 agcgatctac atttctatat gttcaattgc aggaaaataa aacattgctg catttttcac
      121 cagagttcca tctagagggg ctaacattag gagaaatcta tcaagcagaa gggctgtcgg
      181 ctgttttgca cttttttaag gtagaattgg aattaccagt aaaagattat atcgagcttt
      241 ctcttgaatc ttgggatcga gcagtggttg aactgtttcc agaaggttta atgatcgata
      301 caaacgatgg gaagatccat ctgactgcag cagaactgca aaaacaaatg cgttatcaaa
      361 tagatgacga aaattctttt tctattttta gacgtcagca aaagattcta aaaagctttt
      421 taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac acagctgttg aaaaaatatc
      481 caggtctgct tcacacgtct attcaatttc ctcaattgat tacgatgatc catcgtttta
      541 tacgtatgca acagctacca tctaagaagc tgtttcttcc attgacggac acatttcgag
      601 tagtcaacag agaagataaa aagaaagtga ttgtgattga ctttaccaga aatcggaatg
      661 tccttcacca agttgcaatg gaaaaggcca attaaggctt tttctttttg gatttttttg
      721 tcataataaa tattagatga tggaggagat aatatgatgc aaacatggtt agaaaggcta
      781 atacgatttc agcagaacta tcacaaactt atgcagggaa gatatgcgaa atttgatcag
      841 ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt tgctaagtcg ttggttgccc
      901 tatagaatcg gacaattgtt gttcatcgtc tttttcggat ggatgatatt tcgtttccta
      961 tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt atttgaaata tcttgataga
     1021 gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag tcaaaatgga tcgaaaaagt
     1081 tatacttttt ttgagtgccc gaattgtcat caaaagcagc gtgcacctaa aggaaaagga
     1141 cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg aaacgaatgt ttaagggaga
     1201 aaagaatgaa attagtatta ttacgtcatg gcgaaagcga agcaaatttt gaaaattact
     1261 ggacaggatg gctagatgtc gccttaacag aaaaaggaaa agaacaagca gcagttgccg
     1321 gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt ttatacctct gttttgaaac
     1381 gtgcgattct taccggacaa gtcgcactag aagaaatggg tcagttatgg cttcctataa
     1441 taaaaacatg gcgtctaaat gaacggcatt atggggatct tgtgggtaaa aacaaagata
     1501 agatgaaaga aatatacgga aaagatcaag taaaaacatg gcgcagagga tatacggaag
     1561 ttccgccgtt aaccgcagaa aatagatttg accgcagata tgatcacttg gatccgcatt
     1621 tgatcccata cggagaaagt ctggaaatga cagtgaatcg gatcattccc ttatggcaag
     1681 atcatctagc accaaaacta aaagatcggc aagatttact agttgtgggt catggtaata
     1741 gcatccgagc actgacaaaa tatttagaag atgttcctga agatcaaatg gatacgatcg
     1801 atatcccaaa tgcacaacca atccagtata cattagcaga tgatttgaca attctggaca
     1861 aaaaaatact ttaaagaaca cctttatcta aaagtgagag atagaaaaaa gaagcaaagg
     1921 aatggaacaa aaggaacatg aaaaattata tatgggactt tgatggtaca ttgtttgata
     1981 cgtatcccgc aatggtagat ggtgcatggc aagcactaaa agattttggt atcagtatgg
     2041 acaaaaaaga aatctacttc aaaatgaaaa agtattctac tagttatttg atcaatgaat
     2101 caaacttgaa tgccagagag tttaatgaat tatttcaccg atatgaaaaa gaaagtacgg
     2161 aagtttcccg tccatttcca gaaacgaaac aagtactgga aatgctaaaa gacaacggcg
     2221 gtcgtcattt catcctgacc caccgtttga cagaatcaac atggggcctg ttaaaagaac
     2281 atcgattggc acatctgatt gaggaagtag tagggatcga tcaggacttt cctcgtaaac
     2341 ctgatccagc atctttaaat tatttgatcg atacttttca tttagaaaga acagacacga
     2401 tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa aaatgcagga gtcgctactt
     2461 gtctttacga catcgatcat tttctgggtg agatcccggc agattatgtg gtaggaaatc
     2521 tgaatgaaat ccttaccttg cagagcatca ttaaaaagta gtatcccctt tcaaaggaga
     2581 tatgttataa ttttcataaa ggagtgataa aattatatgg aaatcagaag acaaaaagaa
     2641 gttgtagaag catttcatta tgatatgaga ttgccgaacc aagaagtaga aacagatttg
     2701 aaagtaggct tctcgccttt aaaagaaacg atcgaaaact atccgaaaga acatagcatc
     2761 gtaggagcac gcttagagtt ccgtttagtg tttgatacat atgttttatc tggaagtgtg
     2821 agtcagatca atcatatcct caatcggaaa attgaaggtc aaaatgatgt cacacaagaa
     2881 gaagtggacg agctagtagc accgttattc gatatcgtac gccgaatgtc ttatgaggtg
     2941 acagagatcg ccttagatca gcctggggta aaattgaatt ttcaatcaga aaaacaagaa
     3001 tagacagtaa aaacatacct gcgatagatt aaagctatca caggtatgtt tttttattac
     3061 taattgtaag caaaaagaat gtcatttcga taaaaatcgt ctaaaatata aaagtcactg
     3121 aaaaaaattt tttcaggagg atggttgaag aatcattctc gggaaccttt acttccttcg
     3181 atggacttgt cattaataat atgaggagga gaaaaatgac aacactcatc acagttttag
     3241 tggttctagt ttttgcggca ttattatatg tgttctatcg tatgcaaaag cgccatacaa
     3301 aattttcaac acgcgtcttt acagcattag gagttggtat cgtctttggc ggtctgcttc
     3361 aattgatctt tggtgtagac gacaaagtcg ttactcaatc aatggaatgg atcgggattg
     3421 taggtcaagg atatgtatca ttcttgcaaa tgctagttat gcctttagtg tttatttcga
     3481 tcattggtgc attcacaaaa atgaaagttt ctgaaaagct agggaaaatt agtgcgactg
     3541 tattgacttc tttacttgga acaacagcta ttgcagcatt gatcggaatt ggttcaacaa
     3601 tgctgttcgg actccaagga gctaaattca cacaaggagc tgcagaaaca gcacgaatct
     3661 ctgaactggc aacacgtcag gaaacagttg aaaacttatc gattccacag cagattttat
     3721 cctttatccc taaaaacgtt tttgctgatt tagcaggtag tcgtgcaaca agtacgattg
     3781 gagtcgttat tttcgcggca tttgtcggaa tcgcttatct aggcgtgaaa agaaaagcgc
     3841 caaaagaagc agcattcttt tcagatttag tcgacagtct gtataaaatc attatgcgga
     3901 tcgtgacgct tgttttgcgt ttgacacctt atggagtatt tgctttgatg acaaacgttt
     3961 tggcaacaag tgattttgca gctatcgtca atttaggtaa atttgtcgtt gcttcttacg
     4021 tagcattgct tgctgttttg attgtccact cactgatttt gattggtgca aaagtcaatc
     4081 caatcaacta tttcaaaaaa gcctttccgg tattgagctt tgcgtttact tcacgttcaa
     4141 gtgctggagc tttgccattg aatatcgaga ctcagacaaa agctttagga gtagatgatg
     4201 caacagctaa tttctcagca agttttggtt tgtctattgg acaaaacggc tgtgctggcg
     4261 tttatccagc tatgttggca acgatcgtcg caccagcagc tggagtgaat gtctttagtt
     4321 tggaatttat tttgatgctt gtggcaattg taacaatcag ttcttttggt gtagctggag
     4381 tcggtggggg cgcaacattt gcttcactga tcgttttagg ggcaatgaac ttgccagtag
     4441 caatcgttgg gttagttatc tctgttgaac cattaatcga tatggcacgt acagcagtaa
     4501 acgtcagcgg tagcatggta gctggtatcg tgacaagtgc acgcatcaaa gatttagatc
     4561 gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa tgcatagtca aaaagaggtt
     4621 gtgatagaag tggtcagctt taagaaataa gaagaagttt cctaaaaata gtttctcaaa
     4681 tttttgtgaa atttcggctt atttccgaga agctacttct gaaacaccgt gaataagagg
     4741 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4801 attttacgtt tggttgagct tattaccgca gatgcaagct tttgaacacc gtttaagaaa
     4861 gaggtcgtga gcctgccgtt tcactctgag tcacaaagag caatttcaaa aaatagcttc
     4921 tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg tcaggagaac accgtttacc
     4981 agaggttgtg acttgttttt agtcacgacc tcttttttta tttattccat ataaatacac
     5041 attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac aaccaactta tttattatta
     5101 aagaaaagcg tatttaagta ggacgattct gttgagagct ttcgtagatt ttcccatttt
     5161 cctatggtaa actgacaaag ttgagaatgt tagaacag
//
LOCUS       DBGZHO010000105         5192 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.111, whole genome shotgun sequence.
ACCESSION   DBGZHO010000105 DBGZHO010000000
VERSION     DBGZHO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.111"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            137..748
                     /locus_tag="ACN3HL_002715"
     CDS             137..748
                     /locus_tag="ACN3HL_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HHC8007507.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="ACN3HL_002716"
     CDS             821..1750
                     /locus_tag="ACN3HL_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HHC8007508.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1887..2645
                     /locus_tag="ACN3HL_002717"
                     /pseudo
     CDS             1887..2645
                     /locus_tag="ACN3HL_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(2693..3895)
                     /locus_tag="ACN3HL_002718"
     CDS             complement(2693..3895)
                     /locus_tag="ACN3HL_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HHC8007509.1"
                     /translation="MHRKEDFHMNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKT
                     ELTAFLDYEKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYR
                     RTNDTLEKTVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERE
                     LHDRYAAIYMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEI
                     LIDLQERGVKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKE
                     VCDDFKMVYQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKT
                     IYSTNLIESFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTD
                     TLASMFTE"
     gene            3975..4499
                     /locus_tag="ACN3HL_002719"
                     /pseudo
     CDS             3975..4499
                     /locus_tag="ACN3HL_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4706..>5192)
                     /locus_tag="ACN3HL_002720"
     CDS             complement(4706..>5192)
                     /locus_tag="ACN3HL_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HHC8007510.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1642 a          878 c         1003 g         1669 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtcttct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta aa
//
LOCUS       DBGZHO010000106         4955 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.112, whole genome shotgun sequence.
ACCESSION   DBGZHO010000106 DBGZHO010000000
VERSION     DBGZHO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.112"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            209..307
                     /locus_tag="ACN3HL_002721"
                     /pseudo
     CDS             209..307
                     /locus_tag="ACN3HL_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(530..760)
                     /locus_tag="ACN3HL_002722"
     CDS             complement(530..760)
                     /locus_tag="ACN3HL_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HHC8007511.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(990..1808)
                     /locus_tag="ACN3HL_002723"
     CDS             complement(990..1808)
                     /locus_tag="ACN3HL_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HHC8007512.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1969..2658
                     /locus_tag="ACN3HL_002724"
     CDS             1969..2658
                     /locus_tag="ACN3HL_002724"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HHC8007513.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2672..4174
                     /locus_tag="ACN3HL_002725"
     CDS             2672..4174
                     /locus_tag="ACN3HL_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HHC8007514.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            4187..4663
                     /locus_tag="ACN3HL_002726"
     CDS             4187..4663
                     /locus_tag="ACN3HL_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HHC8007515.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(4822..>4955)
                     /locus_tag="ACN3HL_002727"
     CDS             complement(4822..>4955)
                     /locus_tag="ACN3HL_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHC8007516.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         1654 a          719 c          883 g         1699 t
ORIGIN      
        1 aggggcagcg agtgtcgacc ccttctaggg ggattaaaaa tacacccgtc ctcacgggtg
       61 tatgggttac tgatagactt gattttaact ggtgtcagaa acttatgtcc agaaagggtg
      121 atgaaatttt ggcaatttac ggctattcaa gaattagcac aagcaaccaa gattacaaaa
      181 cacaaattca aacattagaa aatgctggcg cagaaataat cttcctagaa aatcactgga
      241 ttatcgaaca cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaactt
      301 aatttgacaa ttaagagtat atttacttca gatggtaagg caacaaaata aaatacaata
      361 ggcagatgaa ctaataaata aaatctgtat taaatacaga taaattaata taaaaatcaa
      421 aaggatcata aacttttaac aagtgatgaa atgggtggaa attgattctt atagacagtt
      481 tgtctcataa cattgaagta ttttgcaatt ttagcattga aacacttttt taatcttcaa
      541 cgttgttctt ataaacaaga tgattgggaa tcttttgaat taacactgta tagcttagaa
      601 caccctttat agaaaacatt cgcttagcaa tcttaataat tccttgtgcc cgatgtcgtt
      661 tagattcagt aggttcctgc tcatcgatca tggaaaaaat ttgaaggatc agatccttaa
      721 taaatttatt taagagagga tgatccattg cttcatccat actcgataaa ctagtgataa
      781 tgagctacac gtttttcttt caagttgatc aatagcttcc acgataaaaa tatctttaga
      841 taaaatcaag aaccgtagga actacaggga tatttggtca ataagagcca ccgctattag
      901 taaaaaataa gctatcaagt atgctctcat cccaagaatt gcctacttca atcgttaaaa
      961 accgttaggt ttagctaagt gggggtagtt cactcaatac ttttatcaat aatagagcgc
     1021 aaaacttttt ctcttaattc aactgaatca atattattgt tttgttcata accatgaact
     1081 aatagatcac aaatataaag ttgtgatatt tttccagcta aagatccacc attaagaaat
     1141 tcttcaatgg ctgtttgtaa aactaagtct gcagactttc ctataggtga atgaatatag
     1201 ttagttatag caataatttt tgcgccattt tttttagcta ttttcaatga atcataagta
     1261 tctttcgttt tcccagataa agaaaaaatg attactaaat cattaactgt taataaagaa
     1321 gcgacttggg cttgaaaatg agggtctagt acagcttttg cttgaactcc tacgcgaaga
     1381 aacatatttt ctaaatcaag actagtattt ccactagatc ccactccaaa tatatatatg
     1441 ttttttgatt gagtgatcat tttaatggct tcattcaatt tttcttcgtc taaaagccta
     1501 atagtggaat agagagcttc tgttaaacta ttagcaattt catcatagta ctttacacta
     1561 gtcggatgtt cttttttttg actaaagtct tcctttgcaa tttcaatttt taaatcagaa
     1621 aaaccagaaa aaccaatttt ttgacaaaag cgaataatag tagcatcgcc aacttttgtg
     1681 tttttcttaa tatcactcat cgtactataa ataatagttt tcccagaatt taaaataaaa
     1741 tcagcgactt ttttttcaga cttcgttaaa aatggataat tttctttaat taaatagata
     1801 taactcatac aaactcctct acaatttcaa cttttctcca ttatactcca aaataataaa
     1861 aaaaactcct aaatactcca tttttatctt tacttttatg aaagcggatg ctatattgtt
     1921 tttggagtta ttatccaaaa ataataaaaa attggagcgt ttaggataat ggataaaaag
     1981 aggtttttag atcttatttc aaaaggtttg attgtttcat gtcaagcatt acctggtgaa
     2041 ccattttaca aagaggaaga aagtttaatg ccttattttg ctttggctgc tcaaagggct
     2101 ggagcagttg gtatacgtgc aaattctgtt cgagatatta ttgaaattag aaagtgtgta
     2161 tcattaccaa tgattggaat tattaaaaga gattatccac cagaatctcc attcattact
     2221 gccactatga gagaagtaga tgaattagta gaaaccggtg ttgaggtaat cgctcttgat
     2281 tgcactctta gaaatcgaca tgatggacta tctataaatt cttttattac taaaataaaa
     2341 gaaaaatatc ctcatcagtt atttatggca gatatttcta catttgaaga aggcaaaaat
     2401 gcatataaag caggaataga ttttgtagga actactttaa gtggatatac tgaggaaagt
     2461 aaaaaacaag atgggccaga tatagatttg attaaaaaat tggtagaaga agggatttgt
     2521 gtaattgctg agggaaggat tcatactcca gaacaagcaa aagagataaa aaaaatagga
     2581 gttgcaggta ttgttgtggg tggtgctatt actcgaccac aggaaattgc atcaagattt
     2641 gttaaagcat taagttaggg ggagaaataa aatgtttaaa aaattttcac aattaggacg
     2701 cgctttcatg ttaccaattg ctatattacc agtagccgga ttactattgg gactgggagg
     2761 agcgttaaca aatgagagtg ctataaatgc ttatccattt ttagatcaac cgtggttgca
     2821 tacaatttta agtattatga gttatgctgg aaatgcagtt tttgcaaacc tagcactaat
     2881 ttttgcaatt ggtattgctg taggacttgc aaatggagat aaaggaacag ctggtttagc
     2941 tggtggagta gcttatttag tatatactgc aactattagt gggtttcttg aacttttttc
     3001 agcaaaagat gcaacactag atacaggtgt agtgggatca attgttgttg gtggtactgt
     3061 tgcattttta cacaatcgtt atagaaaaat tgaattacca caattcttag gtttttttgg
     3121 aggatcaaga tttattccga ttgtttctag tttagctgca atcattattg gttctttctt
     3181 ttatttaatt tggccaccaa ttcaaaatgg tttagtagtt gctggtgaac aaattgccca
     3241 aatgggtagt ttaggaactt ttttatatgg ttttttattg cgtttaacag gtgctgttgg
     3301 actacaccac accatttacc ctttgttctg gtatacatct ttaggtggta ccgaaactgt
     3361 agctggatca acaattgctg gagcccaaaa tattttcttt gcccaactag ctgatccaaa
     3421 ccacactggt ctgtttactt atggtactag attttttgca ggaagatttg caacaatgat
     3481 gtttgggtta ccagcagcat gttatgcaat gtatcgtgca attcctaaga aaaatcgtaa
     3541 aaagaatggt gggctttatt ttagcggggc ccttacatca tttttaactg gaattactga
     3601 accagttgaa tatatgtttt tatttgttgc tccttggctt tatgtgattc atgcattctt
     3661 agatggatta tctttttatt ttgctgatat cttaaatatt cgtgtaggga attccttttc
     3721 aggtggtttg atcgactttt tattattcgg tgtacttcaa gggaatgaca aaactaattg
     3781 gttaaaatta attccttttg gtattgcatg ggcatttata tatttctttg tttttacatt
     3841 ctttatcaaa aaatttaagg tagctattcc tggaatggaa gaagaatcag aagttcattc
     3901 tgaaaaagta ataaacaaaa atacatcatt acatgaagag tctcttatca ttattgaagc
     3961 tcttggtgga aaagaaaata ttgagtctgt tgaagcttgt gcaactcgtt tgcgtgttgc
     4021 tgttacgaat ggggagatta ttcaaaaaca aacaataaaa gacactggtg caactgctgt
     4081 cttcgaagtg aagggtggca tccaagctgt ttttggaggg aaagctgact tattaagtca
     4141 agaaatcaat caaatattag gaaaagataa ttaggaggtt tttaatatgt ttgaaatttt
     4201 caaaaagaaa aaacaagaaa ctttttatgc accttgttcc ggaaaaatca tttccatcac
     4261 agaagtaaat gatcctgtct tttcacaaaa attactaggt gatggttttg ccgtcatacc
     4321 tgatggttca aaaatttatg ctccattggc tggtcgagta acaaatatat ttcctactaa
     4381 acatgctatt aatataaaaa gcaactcagg cattgattat ttgattcata ttggaattga
     4441 tacagttgaa ttacaaggag agcctttttc gatttgtgtt caagaaaatg atgaggttac
     4501 tcctgaaacc tcgttggttg atgtggattt tgacaaaata ataaaatctg gtaaagatac
     4561 ttctgttata gttgtttttc cggagaaaaa tcagttcaat gatttaataa tagataatgg
     4621 tcgaattgct catgggaatt catgtggaaa aatcactttt taaaaaagtg tatataaaaa
     4681 gctataaaat aagctaaata ggatatttgt caaatgaagt tggtgaacag aaagaactgt
     4741 tttctttctg ttcatttttt tattttatta gtaatgattc cccatgccaa atcatgatcc
     4801 gtaatttaaa gttatgattt gtcaaattaa gctagaataa aatgcttctt gtacatagct
     4861 caaaaatatt tcgattggtg ttctgtaatt caatgatttt cttggaatat gattacgttg
     4921 attgctgaca ctggaaataa atgtctgatt cactt
//
LOCUS       DBGZHO010000107         4952 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.113, whole genome shotgun sequence.
ACCESSION   DBGZHO010000107 DBGZHO010000000
VERSION     DBGZHO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.113"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(78..2198)
                     /locus_tag="ACN3HL_002728"
     CDS             complement(78..2198)
                     /locus_tag="ACN3HL_002728"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HHC8007517.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACN3HL_002729"
     CDS             2428..3606
                     /locus_tag="ACN3HL_002729"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HHC8007518.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACN3HL_002730"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACN3HL_002730"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HHC8007519.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACN3HL_002731"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACN3HL_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HHC8007520.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
BASE COUNT         1585 a          865 c         1012 g         1490 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tt
//
LOCUS       DBGZHO010000108         4931 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.114, whole genome shotgun sequence.
ACCESSION   DBGZHO010000108 DBGZHO010000000
VERSION     DBGZHO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.114"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            85..972
                     /locus_tag="ACN3HL_002732"
     CDS             85..972
                     /locus_tag="ACN3HL_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HHC8007521.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACN3HL_002733"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACN3HL_002733"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HHC8007522.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACN3HL_002734"
     CDS             2274..2720
                     /locus_tag="ACN3HL_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HHC8007523.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACN3HL_002735"
     CDS             2993..4345
                     /locus_tag="ACN3HL_002735"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HHC8007524.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACN3HL_002736"
     CDS             4516..4803
                     /locus_tag="ACN3HL_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HHC8007525.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1393 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt t
//
LOCUS       DBGZHO010000109         4656 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.115, whole genome shotgun sequence.
ACCESSION   DBGZHO010000109 DBGZHO010000000
VERSION     DBGZHO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.115"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..402)
                     /locus_tag="ACN3HL_002737"
     CDS             complement(<1..402)
                     /locus_tag="ACN3HL_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HHC8007526.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEI"
     gene            complement(410..967)
                     /gene="hxlB"
                     /locus_tag="ACN3HL_002738"
     CDS             complement(410..967)
                     /gene="hxlB"
                     /locus_tag="ACN3HL_002738"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HHC8007527.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            complement(1007..1711)
                     /locus_tag="ACN3HL_002739"
     CDS             complement(1007..1711)
                     /locus_tag="ACN3HL_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HHC8007528.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            1897..2646
                     /locus_tag="ACN3HL_002740"
     CDS             1897..2646
                     /locus_tag="ACN3HL_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HHC8007529.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            complement(2830..3075)
                     /locus_tag="ACN3HL_002741"
     CDS             complement(2830..3075)
                     /locus_tag="ACN3HL_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007530.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            3395..4156
                     /locus_tag="ACN3HL_002742"
     CDS             3395..4156
                     /locus_tag="ACN3HL_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HHC8007531.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            4384..4578
                     /locus_tag="ACN3HL_002743"
     CDS             4384..4578
                     /locus_tag="ACN3HL_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007532.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT         1500 a          846 c          727 g         1583 t
ORIGIN      
        1 aatttctttt ttcaacacat cacttgcatt tatcacattt tcattagcta cgatattgat
       61 gctatgcttt tgttcaaatc gcttacttaa ggcttgcgca atgatcggtg caatttttac
      121 taaatttatt gcgccaacag atgttgttaa gatatctgca ttttttgttg ctgtaatcac
      181 ctcttctagc tcggataaac tattcagtgc cacaacatga tcaatgaaat cactcctgtt
      241 catttcatca ataatttcga tagtataacc cttatcttga tttaattgat ggatcagttc
      301 aggattcgta tcaataaaac atagatcgaa tccattctga tgtagaattt gtccaataag
      361 ccctctgccg atgttccctg ctccaaaatg taccgctttc atttttcacc tactctaagt
      421 tagcatggta ttgccacaac tttgacatat caattgcttt ttcttctatc atcactaaag
      481 caatactatc tcctaacaaa agaacacttt gttcaaacag gctagtcatt ggctgtatag
      541 aagaaatttc ctctggtaac gctaattttg tttgtacggg tatacgaata aaaagatctg
      601 aatattcttt cattgtgctg tctgggtttg atcctatatg ggcaacttgg gacccaaatt
      661 cctttgcttt ttttgcaata gttagtggga aagcactttc cccactacca gaaccaacaa
      721 tcaataaatc tttatctgta attgccggtt cagtgatttg tcctacgact actgtctgaa
      781 ttcctagatg ccctaagcgt tttgccattc cttctagcgc taacagtact ctgccaaccc
      841 ccacgaaaaa aactcgttcc gctttttcaa ttttctttat caattgttcc acatcttttg
      901 aagaaatacg gtctaatgtt tcagtaattt ctcttacaat attttgtttc gccgccttat
      961 aactcaacta tttcccctcc atttctatta ttcaggacca ctacatctat tgatttttcc
     1021 taactgattg cttcatcgct tgataaagta gtttttgatt ttctgctaat gtatttcctt
     1081 taagaaacaa acttgtactt cctaatacca gatttgttgc gcctgcatct aataatcccg
     1141 ggatcgtttc taacgatacc cgtccatcca cttggatatc tactgctaac tctttctcat
     1201 ttactaactg gcaaagatct gtaatttttt ttagcgcgta agaaacttgt ttttctgact
     1261 tgtttgttgc aaaacctgga ttaatcagca tcaaacaaat cctatcaatc tcgggtaaaa
     1321 tatattgtaa tacatttaac ggagttgctg gattcaaagc tatccctact tttgttccag
     1381 aattcttgat gagctggata tatcgatcaa tatggaggct tgtttcataa tgaaaagtaa
     1441 tgctctctac gccaattttc aacatttctc caataaaaaa ttcgttatcg ttatccttag
     1501 ccatgatgtg tacatcaaaa ttcattgaag tgatttctct aattcttttg attgtttcga
     1561 tccctaaagg catactggga ctaaaagaac cgtcaatcac gtcaatatgc aaggaatcca
     1621 tcccaatact ttctagttct tggatgcttc cttccaaatt tgctagatcc ccacacataa
     1681 gtgaaggcga caaaataatt tttttctcca tacattccct cctttaatta ccccctcatt
     1741 gtaaccgctt aacaaatact agtcaacata aaactgcata aaaatatttt gtttttgctt
     1801 gtttatgcct ttttagtgta ttaaaaacgg aaattattga cataaaaacg cataaatgac
     1861 atgataaaca agaataaata agaaggagca cgcaacatgt tgaaattaga acgtcatcaa
     1921 aaaattctag atttattaaa cgcagaacaa aaagttatcg ctagtgattt aagtcaacgt
     1981 ttcaatgtat ccgaagacac gattcgacga gatttgaaag atttggatag ccaaggtctc
     2041 ttaaaaagag tacacagcgg cgctttacgt gttggtccgc caattaccaa ttttaactac
     2101 cgagaaactg tagctagcga acaaaaaact gcattagctc ataaagccct ccctttttta
     2161 aaagaagaat ctgtcatcat cattgatgga agtacaacta acttggcttt agcaaaagaa
     2221 atcccacaag attttcgtgc aacaatcatt accaatagcc cgccgattgc catagcatta
     2281 gcacagcatc ctaatttgga aattatcaat attggcggta ctttttataa acaatctatg
     2341 atcaatattg gggtacaagc ttataagcaa ctacaaaaca ttcgagccga cctttatatt
     2401 atgggtattt ataacataga tctagatgtt ggaacgagcg tgccaactat gcaagaatcc
     2461 gacattaaac gtgagatgat acgtatttct actgaagtac ttgggatgat aactaatgat
     2521 aaattcggca ccatcagtaa tcatatcgtc ggtccaattg aagaccttac ctatcttatt
     2581 tcagaagaaa ttcctgaaaa ggttcgtaaa gaatacaata aacaaaaaat cgttttgatt
     2641 gattaagcga aaactattgg taactactaa agcaacagat ataaaaaatc taaaaaagaa
     2701 acacgcaata aagttttgaa ataaacttta ttgcgtgttt ccttttttgt ttattctcac
     2761 ttacctagca ccacgtataa catactatag caatcatcat cccacttctt tgtcttttga
     2821 aatactacgt tatttctttt tattaacaaa aaacaatagc actaaacaga ccaaaatagt
     2881 tatgactctc aacgcgggag taaacagcaa tgctatcatt aaattagcaa gttcactgac
     2941 gattgaggaa tttgattcgt ataatacaaa taaaggttct gcaaataaat tcacatgtct
     3001 ataaacaaat tctgtaaata aatatacggt taagcctaaa ccaattatgg tgatattttt
     3061 tttagatttt gacatttttt ctctcctata ataatttttt cagttattca tttccttttt
     3121 tataaaaaat gtagattgtt ttgaagtaat aatatgctgt agtttcaaga aaatttacag
     3181 gaaatttgat aactgatatt atttactttt tgaccaccat atacatgact tttatttttg
     3241 tttctttttt agaatcaaat gtgattaaat agaaaatttt acaataatat gcacatataa
     3301 ataataagat gatataatca acaaagaaaa tgtgattttt ttcactatat tttatcacat
     3361 gaaaattcat taagaaagta ggaatcgaag tattatgcac acaccagaag aaattatgga
     3421 actcagtatt catcttggaa caaaaaaaat acataaacct atcttagcta aactgatttt
     3481 aggttttatc ggaggagcca tgatttctct aggttatttg gcatacgtac gagtctctgc
     3541 ttctatccca gaatctatgg ctagcttgac tagtttagtt ggtgcctcgg tttttcctat
     3601 cggcctgctg gtcatccttc ttggcggtgg tgaattgatc accggaaata tgatggctgt
     3661 ggcgattgcc tttatggata aaaaagtcac attctcacag ctggttaaga attggtcagt
     3721 gattactttt gcaaatatta ttggtgcaat tttcgttgcc tatttctttg gacactttgt
     3781 tggtttaact cattcaggtg tctatctcga ccaagtgatt catattgctg atcataaaat
     3841 cgctgtttct tggtggcaag cattaggctc cggaataggt tgtaattggt ttgtcggttt
     3901 agcgttatgg ttatcatatg gagcaaaaga tgcggccggc aaagtactaa cgatttggtt
     3961 tccagtcatg atttttgtgg caatcggttt ccagcatagt gtggccaact gttttgtgat
     4021 acctgctgcc atatttgaag gtcaagcgac ttggttagaa tttctctcga attttatccc
     4081 cgtttatatt ggaaatatca tcggcggagc tatttttgtt tcaggttttt attacgttag
     4141 ttataagcat cattaagatt gaaggtaatg ttcattcgag cattaccttc aatctcttta
     4201 tatactattt atattttaag aacaatagcc ttttattata tatattattc aaattagtta
     4261 tatcgagtga aaaaaacttt caaattgatt ctttttattt atcataaaga tatagataca
     4321 taatcatttt cacttacata tatttgaata ttaactaaaa acagcaagaa agaagaggat
     4381 caaatgtatt atgtagaagt aaaaacaaaa ggcgtcaaaa acaaacaata tgtgaaaggt
     4441 atcagtaacg aatatccttt acttggttca tggaaagaag ctgctccttt ttccaaacca
     4501 tgtgccataa aaataaagaa cgagctagaa aaagaactga cttgtggcaa agctgttgta
     4561 gatatcatcg aaaagtaaat ccaatgtata gaaaggaaga tcacacatga aaagcgacgt
     4621 acaaattgct aagattatag aattagaaga agaaga
//
LOCUS       DBGZHO010000110         4531 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.116, whole genome shotgun sequence.
ACCESSION   DBGZHO010000110 DBGZHO010000000
VERSION     DBGZHO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.116"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(1..2327)
                     /gene="esp"
                     /locus_tag="ACN3HL_002744"
                     /pseudo
     CDS             complement(1..2327)
                     /gene="esp"
                     /locus_tag="ACN3HL_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
     gene            complement(2944..3378)
                     /locus_tag="ACN3HL_002745"
     CDS             complement(2944..3378)
                     /locus_tag="ACN3HL_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007533.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4531)
                     /locus_tag="ACN3HL_002746"
     CDS             complement(3395..>4531)
                     /locus_tag="ACN3HL_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HHC8007534.1"
                     /translation="NSEFSIIKEYRSDRTTYFFYDYKKLLTDNIKKTKDFHFFTGDFN
                     EMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLG
                     DIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLY
                     ENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLG
                     MDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQ
                     FIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNH
                     TISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1408 a          835 c          621 g         1667 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtcctt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatcctaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat t
//
LOCUS       DBGZHO010000111         4473 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.117, whole genome shotgun sequence.
ACCESSION   DBGZHO010000111 DBGZHO010000000
VERSION     DBGZHO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.117"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            322..1050
                     /locus_tag="ACN3HL_002747"
     CDS             322..1050
                     /locus_tag="ACN3HL_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HHC8007535.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYQFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1195..3222
                     /locus_tag="ACN3HL_002748"
     CDS             1195..3222
                     /locus_tag="ACN3HL_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HHC8007536.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3330..4427
                     /locus_tag="ACN3HL_002749"
     CDS             3330..4427
                     /locus_tag="ACN3HL_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HHC8007537.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1571 a          717 c          924 g         1261 t
ORIGIN      
        1 aatataatat acatttttta tttaattata attaatattg attgaagtct aggcagtcaa
       61 gtcacatttt gatagatagg agggggactt acgaattatt ttaaaggcta tgacagctgt
      121 atttctagat tgtgtttgca tcaagttgca ataaaaacta gaaatcaaat cgggctgata
      181 atcatttata actaatcgat acataggacc aaatataggt ctatgttctt ttatttcata
      241 agtatcgtaa aacagaattt tgctatggat taatccaatc gactgatatg tttagtaaat
      301 aaagaaagag gaatgtcaat gatgaaaaaa gaaatcgtat taacagcagc aatgatgtta
      361 ttcagcatgg tagcaagtac gacttttgtt tctgcaactg aagtataccc aaaggaatat
      421 aacacagaag gaacgattac atttgaagca ggagatgagg gtgtaactcc tcctgttgat
      481 ccagagaatc ctgatcccaa taaacctgtc gatccatcag atcctccaag ccctggaaca
      541 ggaggggcat tatcgattga ttatggatca aaattcaaat ttgggactca aaaaatttct
      601 actgcggata aaacgtatta tgcagctgct gatgtgatga acgatgggtc tagaaaaccg
      661 acatatgtcc aagtgacaga taggagaagt accttatctg ggtggaaatt aagtgtctct
      721 caaccagaac agtttaaaac tgccagtggg gatgaactag ttggagcaca gctgaaattt
      781 acgaaagggc aggctgtttc tttggttgat ccaacatata cgccgcaaac ggtgaattct
      841 gaattaacgt tgacaccggg aggaaacaat acgttagcaa ttaatgctaa atcaggaaca
      901 ggtgtgggga cttgggtcta tcaatttggt gcaaatgaaa atgaaaatca agatgcggta
      961 cagctttcgg tacccggtaa atctgtcaag ttagcgcaac aatattccac taaattagtt
     1021 tggacattag aagatacacc taacaactag tttactgaaa agaactgtta aaaataaata
     1081 cgtagtcata ttgtcttgcg aggtaatcga gcaaaaattg tcaaaggcta ggctaaattt
     1141 gtttggatac gaatagttca tctaggaatt taacgatcag gaggaaaaga tatattgaaa
     1201 aagaggagga tcgtgctcat tttaagcagt ctcttagtga ctaatatctt tccgatcata
     1261 gggtactctt tggaattgaa tcagttggag catggaaata gaagagacga agaaagcaaa
     1321 ctcacttcga cattcgacag tttaatagaa tccaaccaga cacaagaaag cagtgaggat
     1381 ttaagtattt cgagtagtgg agagaccact gacaacgtag aagctgaggg ttcggacaaa
     1441 caaggactag aagatgcacc aatttctgcg gttgagctgc ctgacgatcc caatattatt
     1501 tctatcgata aaatttttca aacacctatc ggtactagca cgtccatatt ggaaaatggg
     1561 aagttactgc agttgaaccc agcagaaagg tctcaaagag gagctatttg gtcaaataag
     1621 aagattagtt tactctcgga ttttacattt aaatcttatt tatacttagg aaatcaacga
     1681 gatagagcgg gagatggcat gacctttaca ttgactggcg atcctagaat ggctagtaat
     1741 cccagtcaag ttattggatc gccaggtatg ggaattggct catattctac tcgttctggc
     1801 caaccttaca ttgcgaatgc gctctcgatt gagtttgata cgtataaaaa tagtggttct
     1861 tctgatcgaa tggatcgaga gataactgct gataatagag ggcatggaca tgtcgctttt
     1921 gtcacgccta aaccaaataa taataattat tctggagagc atactggcgt gacggtagct
     1981 cctacatttc tttctaatgg cacatggcgc ttgttaataa ttaaatggga cgcggagcaa
     2041 agaagtctta cttatgattt ggaaggtgtc ggtcactctt ctcggattat acctgatctc
     2101 attaggcagt ttggttctac agaagtaaat tgggggttta cttcttcaac aggtactttt
     2161 tttcaagaaa atgctgtcgc tgtcacgcga cttccatcga atgtcacatc aacagctgat
     2221 gtaaaagtca acgatagtga ttatggggcc atcgctgaag ctggaggaaa cgataagata
     2281 actatcagaa atacattgaa ggtcgagggg gattttcttg aatataagaa aatgcagact
     2341 agtatcgacc tcccacaaga attaactatt cccgagcata tcttgatcaa tggaaatcaa
     2401 attgatgcca aagatatctt gataaccgga aatcgagtca cgctaaatct gacagattat
     2461 tttattgctg gagatacgtt aataatcgaa ttggagacaa ctttgcagga agtaattcct
     2521 gaaaaagtac tcactatgca ttttgaatac cttgaaaacg ggaatttgat tgagcaatcg
     2581 aatgaaataa acctaaagat cgcaaagctg aaggagatag atatccatgt ttattataaa
     2641 gataaagaca gtcagattga tattgctgaa atgaaaacaa tcactgggaa aataggagag
     2701 aagtataaag aaactcctat tgatattgaa gggtatgttt ttgactcgga ttcagcgaat
     2761 acagaaggca tcttctccga aaatacagag gatatctatt tttattacag aaaaggcaaa
     2821 ctttatctct caactgctcc tcaatatgtc aattttggaa aacataaaat atccagtaga
     2881 ccattaagtg aattcggaca gttttcaggt gggttgaaaa ttatagatga acgggctttt
     2941 ggaagttgga aattacaatt gaaacaagag aaagttctta caaatggaga ttttgagctt
     3001 ccagaagctc tttcctttgt tacctctgaa aatacaacgg ttatagggac atccgctgtt
     3061 acgattttcg aaagtgatca aaagggtgaa agcgatttgt cctctctttt agattctaca
     3121 gctcatcgtg gaatcagaat agatattcct gtagaaaacc aaagaatcgg aacctttgag
     3181 gggaaactat cttggatact tgcagatgtc ccaggaaatt aacaggaaga gaagaatata
     3241 acaaaattat tgagtttcaa gaagggcaca ggtaccatag gctcttgtgt cccacagaga
     3301 caagattttg ttatagtctt ctcttacata tgattaaagg agcgattttc ttgagaccaa
     3361 aacaacaatt atttataaca ctcctagtta ttttaggggc actttttaac aatatatcag
     3421 tgtcagctag tgcatttaat ttttcagtga cgccgataac ttcagagaat caaatcgaca
     3481 agagaaaaac ttacttcgat cttcaacttg atccggatca ggaagtagaa gtaaaagcgg
     3541 aattgagaaa tgatacagaa aaagaagtga aaatcgatat ttctgtgaat agcgcaacca
     3601 ccaattcaaa tgtgatggtt gaatacggaa aaaacgagat tgaaaaagac atgagcctga
     3661 tctttgatct ggtagattat gtgagctatc cacagatagt gacgctaaaa cctaaaagtg
     3721 tccaaaccgt tgcttttcat gtcaggatgc cgaatgagcg atttgatggt gtattggctg
     3781 gtgggatcac attccaagaa atccagacgg aaaaggacca aacagaaact aaggatcaaa
     3841 gcttatcgat tgagaatgaa tacacctata ttattgcttt gttgatgcaa cagacactga
     3901 acgaagttgc tccgaacctt actcttcatg aagttaaacc agatcaaatc aatgcaagaa
     3961 atgtcatctt agcaaacgtt caaaatgatc aaaaaaccta tatcaatcaa gtagttattg
     4021 aaacaaaaat tacaaaaaaa ggacattctg aagttttata tcaagaggaa aaagaaggat
     4081 tgcagattgc gccgaataca aatttttctt ttccaactgc tttaaatggt caaccgctaa
     4141 ccccaggtga atatcacctt acaatgactg ttttaggaaa tgaaaatgaa aatggaaaat
     4201 tttcgagaaa aaaaggaaat actacgatca actataccaa tcaatgggta tttgaaaaag
     4261 attttacaat agacggaaaa gtagccaagg aattgaacac gacggatgtt acgattaaaa
     4321 aagacaataa ttggatttat atcttagtag cttcactttt cttattgttt attttattat
     4381 gcatactttt gtttgttttg agaaaaaaag aagagaaaga aaagtaaggt taagataaca
     4441 aatagtaaat ttttattatt gtaggatggt tgg
//
LOCUS       DBGZHO010000112         4461 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.118, whole genome shotgun sequence.
ACCESSION   DBGZHO010000112 DBGZHO010000000
VERSION     DBGZHO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.118"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            574..1008
                     /gene="bacA"
                     /locus_tag="ACN3HL_002750"
     CDS             574..1008
                     /gene="bacA"
                     /locus_tag="ACN3HL_002750"
                     /inference="COORDINATES: protein motif:HMM:NF041453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HHC8007538.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="ACN3HL_002751"
     CDS             2298..3221
                     /locus_tag="ACN3HL_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HHC8007539.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="ACN3HL_002752"
     CDS             3237..3776
                     /locus_tag="ACN3HL_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HHC8007540.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DBGZHO010000113         4430 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.119, whole genome shotgun sequence.
ACCESSION   DBGZHO010000113 DBGZHO010000000
VERSION     DBGZHO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.119"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(205..660)
                     /locus_tag="ACN3HL_002753"
     CDS             complement(205..660)
                     /locus_tag="ACN3HL_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LMxysn_1693 family intestinal colonization
                     protein"
                     /protein_id="HHC8007541.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1068..1238)
                     /locus_tag="ACN3HL_002754"
     CDS             complement(1068..1238)
                     /locus_tag="ACN3HL_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007542.1"
                     /translation="MTRKKLIFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(1254..1724)
                     /locus_tag="ACN3HL_002755"
     CDS             complement(1254..1724)
                     /locus_tag="ACN3HL_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHC8007543.1"
                     /translation="MTDKSIKEFAEELGVSKQAIRKYFDKLPTKLTPKLIGGKYVISA
                     KAQEFIKNSINQINEVDTEVDSLVDSILIAELKEKNKQIDHLQGVIEIQQKLLDQQQQ
                     LTLQANQQIDKLQKRLQLVYTEETSENESTTLSEETESIEKQTKKKQKWWKLWK"
     gene            complement(1734..2702)
                     /locus_tag="ACN3HL_002756"
     CDS             complement(1734..2702)
                     /locus_tag="ACN3HL_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HHC8007544.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNRALELANRQTQHEKETTSLQERIKEQKRKLELL
                     QQLEELEKQQKNRENETDKQKLDNNSDIPLELRKDLLDNLQNLFKD"
     gene            complement(3883..4047)
                     /locus_tag="ACN3HL_002757"
     CDS             complement(3883..4047)
                     /locus_tag="ACN3HL_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007545.1"
                     /translation="MKLTKLTISLVIIAGIILYFVLPANQFFLYFGIPTILIVNGVRI
                     FEQRKKCSST"
     gene            complement(4066..>4430)
                     /locus_tag="ACN3HL_002758"
     CDS             complement(4066..>4430)
                     /locus_tag="ACN3HL_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HHC8007546.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1371 a          737 c          707 g         1615 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tacggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtcgactatg ccaagtagcc cttgtatcaa ccgatacaga ggctcacttt
      841 gtgattttgg attggtctag gtaaaaagct ctttttaagg cttgattttt cgcggttatc
      901 tatatctaat tctttgtgca tttttatctg tcatttttta aagacttgtt atttttgaga
      961 ggatttgata cgctttgttt gtatctcatt ttcatctaat aaatggttta tgttgctaaa
     1021 ctaggataat ctcattttgg gctgctcgtt agagcagtct ttttttatta tttatccgtt
     1081 tcttttacaa ataactcttc gttaggactg ttgtaataat ttggattcaa tttcaattca
     1141 ccatgtttat ttcctttatt gatcactgac aataacatcg gactgaagcc tagaattcct
     1201 agtaaaatag aaccaaatat gagctttttt cttgtcatga atgtttcctc cagttatttc
     1261 catagtttcc accatttttg cttcttcttt gtttgttttt ctatcgattc tgtttcttca
     1321 gaaagagtag ttgattcatt ttctgaagtt tcttccgtat aaactaattg taaccgtttt
     1381 tgtagtttgt cgatttgttg atttgcctgc aaggtgagtt gttgttgctg gtcgagtaat
     1441 ttttgttgta tttctatgac cccttgtaaa tgatcaattt gtttgttttt ttcttttaat
     1501 tctgcaatta aaatactatc aactaaactg tcaacttcag tatcaacttc atttatttgg
     1561 ttgatactat tttttataaa ctcttgagct tttgctgata ttacgtattt tccacctatc
     1621 aacttaggtg tcaacttggt tggcagttta tcaaaatact ttctaatggc ttgtttgctg
     1681 acacctagtt cttctgcaaa ttcttttatt gatttatctg tcatgaatac tccttagtct
     1741 ttaaataagt tttgaagatt atcaagtaag tcttttctta gttctagagg aatatcggaa
     1801 ttgttgtcta acttttgttt atccgtttcg ttttctctat ttttttgttg tttttctaac
     1861 tcttctaact gttgtaaaag ttctaatttt cgcttttgtt ccttaattct ttcttgtaat
     1921 gaagtagttt ctttttcgtg ttgagtttgt cgattagcta gttctaaagc ccgattttgt
     1981 tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt ttttgatttc tggtttaaat
     2041 gtgaattggt agccaatgac aggcttccca cggccttttc cgtatttctt tttgattgtt
     2101 aaacctttaa agattgcggt tagttcttgt cgtattggat tgaacacacg ttgatcgatc
     2161 gtaccttggt tgtaactttt aggaatatca agtaattcat gaaagtcttc ttttgaaaaa
     2221 taagcgaaac ctttggttct gtattgtttt agtaatcgaa acattgtttt tgaataactg
     2281 ctttctaatt cattgaattg ttggagagaa tagcgcaccc attcttcaag attattaagt
     2341 aagggtaagg ctttttcatg aacttgtatt tcagcaaaag gaatatcagc ttttccgtcg
     2401 attttaaatt gattaaataa aacaaaacgt tcacgttgca aaccgtcagc acttcttcta
     2461 ccaaaacgta aatccattaa tttgtcatac gttgtttcta aatcatctat gaatcgaaca
     2521 tttgcagttg ctttataatt gcttaaatct tttaattgct cgaatgtaaa ttgtactttt
     2581 ttatcaccta catcacgcat tcttgatacg atagagaaga acaaattcat ttcgactggt
     2641 gtaaattttc gcaacggaat tgtatttaat tcatgatgat actttacgat ttcattagac
     2701 atatttaaaa tagctccttt cttactcgca caagagatac agacgttatg aaatacaaaa
     2761 tgtctgttta tctacatctt atattaacat cgtcgatgta ctaattcaat gtacaaacag
     2821 acaaaacgat gtagataaac agacaaaacg atgtagataa acagacaaaa cgatgtagat
     2881 aaacagacaa aacgatgtag ataaacagac aaaacgatgt agataaaagc gtcattccct
     2941 tgggagagta aggatacagc cgacggtaaa gaggtttaaa aagaggttta aaaagagatt
     3001 ataaaagagg gggacaaaat ttcccgccta aaaaaccact tcttttttct ccaaacagat
     3061 tcgcgcattt ttctaaactg ggaatcttac tccctatagt tgcttaaaaa ggtgtgatcg
     3121 ctctgctctc acattatact gcgcagtcgc ctccggctcc tttgctaaaa ctgttcataa
     3181 ggaactcttt gagaagctat gagccttcgt ttgagacgtt ttaagacagt cttagtataa
     3241 atcccttatc ttgttcttaa agcgccttac aggcggtcag ggcaagccct aacaacccta
     3301 aaattgtctg aattccctct aaaattcgat ttaagcactc ttaactctat tcttatatat
     3361 ttatatactt agacatttga aacgccttaa aacgcaaatt agagcttgat aaagatattt
     3421 gctcgtgtgc ctagactttt aaaaaagtcg gcacacgcca tgacaaagct gaaataaact
     3481 gtttcagctt tgtcatggcg gattcgctca cttgaaaaag tgttcatttc gctcgattat
     3541 tagcatatat tttttcgctt ttttgctagc caaattttgc attagttcgc tcataagtcc
     3601 caccctttca gtacgtccga gggacgtatc gttcgtaatg tgagagtgcc tataaggtca
     3661 ctctctacaa aactcactaa aagggtttgg caagctctat atttgctagc caaataccta
     3721 cgtatttggt gcaaataacc gcttgtcaaa ggggcgcaag ctcccccttg aatcccccct
     3781 caaaacccac gctccacaat acaaaaaagg ctagcaaatg ctagccactt tttgtaaagt
     3841 ttcgcttgtt tcaccttcgg tgaaattgtt gctttgcaac gatcaggtag agctacattt
     3901 ttttcgttgt tcaaatattc ttacgccatt tactattaaa atcgtaggta ttccaaagta
     3961 aagaaaaaat tgattagcag gtaatacaaa atataaaata ataccagcaa taattaccaa
     4021 acttatagta agttttgtta atttcataaa gtatgccacc ttatcttata tagatatcaa
     4081 atagattaat atgccgattg tattataaaa tccatgagca actatggaat accatatatt
     4141 ttttgtttgt atataaacaa aacttaaaat aataccaata aagaaaatac ttaggcctcc
     4201 cccatgaaca atagaaaaca gaaaagaaga aattagtatt gaaatatatt gttgtttttt
     4261 gtttgcttga ggatcaatca tacaaaatcg aaaaattcct tcttctaaaa aagctccata
     4321 agtagcagca tttaaaaaga ataaaaggag agaaccattt acttcattag gatttatacc
     4381 ttctgaaaaa gatgtattta gaatattgat taggaataaa acagagaatg
//
LOCUS       DBGZHO010000114         4424 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.120, whole genome shotgun sequence.
ACCESSION   DBGZHO010000114 DBGZHO010000000
VERSION     DBGZHO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.120"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            690..1658
                     /locus_tag="ACN3HL_002759"
     CDS             690..1658
                     /locus_tag="ACN3HL_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HHC8007547.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="ACN3HL_002760"
     CDS             1669..2484
                     /locus_tag="ACN3HL_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HHC8007548.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="ACN3HL_002761"
     CDS             2552..3262
                     /locus_tag="ACN3HL_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HHC8007549.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4424
                     /locus_tag="ACN3HL_002762"
     CDS             3298..>4424
                     /locus_tag="ACN3HL_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHC8007550.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         1490 a          661 c          921 g         1352 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaa
//
LOCUS       DBGZHO010000115         4416 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.121, whole genome shotgun sequence.
ACCESSION   DBGZHO010000115 DBGZHO010000000
VERSION     DBGZHO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.121"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            59..913
                     /locus_tag="ACN3HL_002763"
     CDS             59..913
                     /locus_tag="ACN3HL_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HHC8007551.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACN3HL_002764"
     CDS             1010..3259
                     /locus_tag="ACN3HL_002764"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HHC8007552.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     NWVITQEEK"
     gene            3262..>4416
                     /locus_tag="ACN3HL_002765"
     CDS             3262..>4416
                     /locus_tag="ACN3HL_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HHC8007553.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1557 a          625 c          806 g         1428 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga attgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DBGZHO010000116         4396 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.122, whole genome shotgun sequence.
ACCESSION   DBGZHO010000116 DBGZHO010000000
VERSION     DBGZHO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.122"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(65..1285)
                     /locus_tag="ACN3HL_002766"
     CDS             complement(65..1285)
                     /locus_tag="ACN3HL_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HHC8007554.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="ACN3HL_002767"
     CDS             complement(1305..1916)
                     /locus_tag="ACN3HL_002767"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HHC8007555.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="ACN3HL_002768"
     CDS             complement(1959..2891)
                     /locus_tag="ACN3HL_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HHC8007556.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="ACN3HL_002769"
     CDS             complement(3312..4172)
                     /locus_tag="ACN3HL_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8007557.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
     gene            complement(4304..>4396)
                     /locus_tag="ACN3HL_002770"
     CDS             complement(4304..>4396)
                     /locus_tag="ACN3HL_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HHC8007558.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIQA"
BASE COUNT         1253 a          886 c          722 g         1535 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct tggattccca
     4321 ataatacctt gatttcagta cagaccgaaa acccgaagag agtgccttct tttcgggttt
     4381 tcttatataa tcctcg
//
LOCUS       DBGZHO010000117         4226 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.123, whole genome shotgun sequence.
ACCESSION   DBGZHO010000117 DBGZHO010000000
VERSION     DBGZHO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.123"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1287
                     /locus_tag="ACN3HL_002771"
     CDS             <1..1287
                     /locus_tag="ACN3HL_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HHC8007559.1"
                     /translation="SLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFK
                     IEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEI
                     VILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDS
                     DPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIY
                     APQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVC
                     LTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="ACN3HL_002772"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="ACN3HL_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HHC8007560.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..>4226
                     /gene="mobV"
                     /locus_tag="ACN3HL_002773"
     CDS             3322..>4226
                     /gene="mobV"
                     /locus_tag="ACN3HL_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HHC8007561.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGEHGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKK"
BASE COUNT         1385 a          635 c          870 g         1336 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caagaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtataatgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacatgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaatt
//
LOCUS       DBGZHO010000118         4118 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.124, whole genome shotgun sequence.
ACCESSION   DBGZHO010000118 DBGZHO010000000
VERSION     DBGZHO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.124"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            114..275
                     /locus_tag="ACN3HL_002774"
     CDS             114..275
                     /locus_tag="ACN3HL_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HHC8007562.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            294..1571
                     /locus_tag="ACN3HL_002775"
     CDS             294..1571
                     /locus_tag="ACN3HL_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007563.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1581..2237
                     /locus_tag="ACN3HL_002776"
     CDS             1581..2237
                     /locus_tag="ACN3HL_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007564.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2237..3613
                     /locus_tag="ACN3HL_002777"
     CDS             2237..3613
                     /locus_tag="ACN3HL_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007565.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3743..>4118
                     /locus_tag="ACN3HL_002778"
     CDS             3743..>4118
                     /locus_tag="ACN3HL_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014479650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HHC8007566.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSS"
BASE COUNT         1632 a          456 c          723 g         1307 t
ORIGIN      
        1 tgtttgaatt cttttgaata ggttcttcgt tgacgtcttg gcatgaaaaa tcctccagtg
       61 tgttttttat tattctacac accttatttt ttctgtctag tctagtgtag ccgattcagg
      121 ataaggataa gtgtattaat tgtggaaaat gtaaaaaagt ttgccaaatg aataaagatt
      181 cagttgagaa ttgcaatcat ctggagtgta tcagatgtgg acgatgtaaa aatgcttgtc
      241 cagtggatgc aattagttat ggagtaagaa aatagagagg agtagttagg aaagtgataa
      301 aaaatgctat agcatatatt acaagaaaga aaaatagaac tttaataatt tttatcatat
      361 taactatagt tctttcttgc ttgtattctt gtttaacaat aatgaaatca agcaatgaaa
      421 tagaaaaggc tttatatgaa agttctaatt cttcaatatc aataacaaaa aaagatggta
      481 aatattttaa tgttaatcaa tttaaagata ttgaaaaatt aaaagaaatt gaagaaaaaa
      541 taattcaata tgatggatta gcaaaactaa aagatgctaa agtagttagc ggagaacaaa
      601 gaataaatag agaagattta tctgacgaat ttaagaatgt tgtttcactc gaagctacaa
      661 ataatactaa aagaaatatt ttatttagta gtggagtatt tacaattaaa gaaggtaaaa
      721 atatagaaga aaatgataag aattcaatta ttgttcatga agaatttgct aaacaaaaca
      781 atctaaaatt aggtgatgaa gttgatcttg aattactaga tattgaaaaa agtggaaaaa
      841 taaaaagtca taaatttaaa attataggga tcttttctgg taaaaaacag gaaacatata
      901 caggattatc ttctgatttt agtgaaaata tggtgtttgt agattattca acaagccaag
      961 agatattaaa taattcagaa aataatgaaa ttgcaaataa aattttaatg tattctggta
     1021 gtgcagaatc tacagactta gccttaaaca aattgaaaga gcttaaaatt gatgagtcaa
     1081 agtattttgt tgaaaaagat tctaatgcgt ttgaagagtc tttagagtca gtgagtggaa
     1141 taaaatatat aataaaagta atgacttatt ctattatgtt aggtgggatg gttgttcttt
     1201 cattaatctt gattctatgg ttaagggaaa gaatttatga aataggtata ttcttatcta
     1261 ttggaacatc taagatacaa attataatgc aatttatatt cgagttaata ttcatatcga
     1321 taccaagtat aatatcttcc ttatttttag gaaatgtatt actaaaagta attgtagatg
     1381 gattcattaa ctcagaggat tcaatgattt ccggtggaag tttaataaat aatagtagtt
     1441 ttatgtcaaa tataacaaca cttggacaaa gttatttaat attaataagt attattgttt
     1501 tatcagttgt atttgcttct tcattaatgt taatcaagaa gcctaaagaa atcttatcaa
     1561 aaataagtta ggagaaaata atggatatat tagaaataaa gaatgtagca tatagttatg
     1621 caaattctaa agaaaaagtt ttgtcaggag taaatcaaaa atttgaactt gggaagtttt
     1681 atgcgatagt aggaaagtca ggaacaggaa aatctacact tctttcctta cttgctggac
     1741 ttgataaacc tcaaacagga aaaatattgt ttaagaatga agatatacaa aataaaggat
     1801 atagtaatca tagaaaaaat aatatatctt tagtatttca aaactataat ttaatagatt
     1861 atttatcacc aattgaaaat attagattag taaataaatc agcagatgaa agtatcttgt
     1921 ttgaactagg tttagataaa aaacaaataa aaagaaatgt tatgaaatta tctggtggac
     1981 agcaacaaag agtagctatt gctagagcat tggtatcaga tgctccaata atactagctg
     2041 atgagcctac tggtaatcta gacagtgtta ctgctggaga aataattaat atattaaaga
     2101 cattagctaa agatagaaat aaatgtgtaa tagttgtaac acatagtaag gaagtagcag
     2161 attctgcgga tatcatttta gaactaagtg gtaaaaagtt gaaaaaagta aataaaatga
     2221 atttggaggt tgaataatga taaaaaatgc atttgcttat gtaactagaa aaagtttaaa
     2281 atcattaatt atcatattag ttattttatc tatgtcaact ttaagtctca ttagtttatc
     2341 tattaaagat gctacggaca gagcttcaaa agaaacattt gctaatataa caaatagttt
     2401 ttctatggag ataaatagac aagtaaatcc aggaacacct agaggtgggg gaaatgtaaa
     2461 aggtgaagat attaaaaaga tatctcaaac agatagtata gactcctatg taaaaagaat
     2521 aaacagtgtt gcagatttag ttgattatga tattattgaa actcaagaga ctcttgcgaa
     2581 tcaatcacct gaaagagcaa agaattttaa aagaacagtt atgttaactg gggttaacga
     2641 ctcaacaaaa gaaacaaaat ttgtatcaga agcatataaa ttagtagaag gaaagcattt
     2701 agaaaatgaa gataaaaata aaatcttaat gcataaagat ttagctgaaa aaaataacct
     2761 taaagttgga gataagataa aaataaaatc taatttattt gatgctgata atgagaaagg
     2821 tgcagatgaa acagtagaag tagaaattaa aggtctattc gatgggcata atagcggtgt
     2881 agtaagtgca gcacaagaac tatacgaaaa tacattaatc actgatattc atacagctgc
     2941 taaagtttat ggtaataccg aagatacagc tgtataccaa gatgcaacat tctttgtaaa
     3001 aggtgataag aatcttgata gtgtaataaa agatcttggg aaattagata taaattggag
     3061 agaatataat ttgattaaaa gttcatcaaa ttaccctgca ttacaacaat ctatatcagg
     3121 tatttactca atttcaaata aattattttt tggctcatta atatttgcag gagttgtagt
     3181 ttcattatta ttattcttat ggatgaatgc tagaaagaaa gaaatagcag tattactatc
     3241 attaggtata tcaaaattag aaatttttgg tcaattccta attgagatgg tatttatatc
     3301 aatccccgca ttcgttggtt cctatttctt agctcaatat acagctgaca agcttgggaa
     3361 taatatattg aataaggtta ctggtgatat agctaaacaa atagctaaac aatctgcatc
     3421 tagccaatta ggtggtgggg cagaagctga aggatttaac aagacattat caagtttaga
     3481 tatcaatgta ttacctaaat tcatgattta tgtagttata tttatgagtt tagtacttct
     3541 tgtatcattg attatttctt cattcaatat attaagaagg aatccaaaag aattattaat
     3601 tgacaataat taaaattttc ggtgcttttt agcaccaaaa atgagagtgt aatataaacc
     3661 gtgtaagtaa ccatcaatcc taggcgggtg gttgcttcac ggtttttatt tttctaaaat
     3721 aagatcaaga ggtgattaca cgatggctag aaagaaaaga aatcctgatg ctgagaagtt
     3781 agctgaatcc attttgaata cttatcaacc cgaatctgta gaggatatgc aagatgtttt
     3841 aaaagatgtg tttggtccct tatttgaaaa aatgcttcaa ggagaattga ataaccattt
     3901 agggtatgac gcccattcta aagagccaaa gaaacatgac aatcgacgaa acggttatgg
     3961 caataagacg cttaaaacga gctttggtaa agtaaacatt gatgttccca gagaccggga
     4021 ggcttctttt gaacctgagt tgattcctaa tagaaaacga gatgtctccg acatcgcaga
     4081 ctgtagacaa aagctgttcc aaactcgtaa ctcgagct
//
LOCUS       DBGZHO010000119         4092 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.125, whole genome shotgun sequence.
ACCESSION   DBGZHO010000119 DBGZHO010000000
VERSION     DBGZHO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.125"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..153)
                     /locus_tag="ACN3HL_002779"
     CDS             complement(<1..153)
                     /locus_tag="ACN3HL_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HHC8007567.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(475..696)
                     /locus_tag="ACN3HL_002780"
     CDS             complement(475..696)
                     /locus_tag="ACN3HL_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007568.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(794..1039)
                     /locus_tag="ACN3HL_002781"
     CDS             complement(794..1039)
                     /locus_tag="ACN3HL_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007569.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1279..1893
                     /locus_tag="ACN3HL_002782"
                     /pseudo
     CDS             1279..1893
                     /locus_tag="ACN3HL_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2263..3264)
                     /locus_tag="ACN3HL_002783"
     CDS             complement(2263..3264)
                     /locus_tag="ACN3HL_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HHC8007570.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3423..3689)
                     /locus_tag="ACN3HL_002784"
     CDS             complement(3423..3689)
                     /locus_tag="ACN3HL_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HHC8007571.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3679..4035)
                     /locus_tag="ACN3HL_002785"
     CDS             complement(3679..4035)
                     /locus_tag="ACN3HL_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HHC8007572.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1295 a          744 c          542 g         1511 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
      241 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
      301 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
      361 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
      421 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
      481 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
      541 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
      601 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
      661 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
      721 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
      781 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
      841 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
      901 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
      961 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     1021 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     1081 tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta
     1141 tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa
     1201 atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata
     1261 gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat
     1321 gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa
     1381 caatctggag cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga
     1441 gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt
     1501 atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg
     1561 atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga cttaatcatt
     1621 taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa
     1681 ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca
     1741 gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat
     1801 ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga
     1861 ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta
     1921 attagctttg tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat
     1981 ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta
     2041 aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat aagatttgaa
     2101 ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc
     2161 acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt
     2221 ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga
     2281 ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac
     2341 agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat
     2401 caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc
     2461 cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt
     2521 gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga
     2581 attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg
     2641 atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat
     2701 tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt
     2761 ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt
     2821 gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat
     2881 atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc
     2941 tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac
     3001 tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg
     3061 tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc
     3121 ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata
     3181 tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac
     3241 ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa
     3301 tttttgtata aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa
     3361 aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc
     3421 ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta
     3481 tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct
     3541 ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc
     3601 gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc
     3661 ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc
     3721 atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac
     3781 ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact
     3841 tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag
     3901 catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg
     3961 taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa
     4021 agatattttt tccataccca attatatcat atattgattt tatattatag tatataacat
     4081 aaaaattcga at
//
LOCUS       DBGZHO010000120         3680 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.127, whole genome shotgun sequence.
ACCESSION   DBGZHO010000120 DBGZHO010000000
VERSION     DBGZHO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.127"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..276
                     /locus_tag="ACN3HL_002786"
     CDS             <1..276
                     /locus_tag="ACN3HL_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HHC8007573.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            419..640
                     /locus_tag="ACN3HL_002787"
     CDS             419..640
                     /locus_tag="ACN3HL_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007574.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            656..1498
                     /locus_tag="ACN3HL_002788"
     CDS             656..1498
                     /locus_tag="ACN3HL_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007575.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1561..3363
                     /locus_tag="ACN3HL_002789"
     CDS             1561..3363
                     /locus_tag="ACN3HL_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HHC8007576.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3422..>3680)
                     /locus_tag="ACN3HL_002790"
     CDS             complement(3422..>3680)
                     /locus_tag="ACN3HL_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HHC8007577.1"
                     /translation="GITISIPPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1311 a          522 c          750 g         1097 t
ORIGIN      
        1 gaactcatca agctggctaa taagggtcaa gattatgaac atctagcaga tgagattgat
       61 gagctgagag acaagcgaca gctcctttta gtagaagatg cctccctcag tggcgagaac
      121 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgtac cttagagtac
      181 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaaga acacttcgtc
      241 atatccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
      301 ttctacagta gagtcgtggg ttttcttttg cttgctgatt ataataatat tttaataact
      361 attgttatta taaaccaaat gatttataat attcttagcg taaacttgga ggtgctgtat
      421 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
      481 tgctagacgt attggacaga ctccacagaa tttcaataag aaattacaac gagaaacggt
      541 aaccttagat gagttgaaag cgattgctga tgtgctaggt gtcaagtttg tgcaggcttt
      601 tatattgcct gatggcaatg aaataaagat aggtaattag gaggtgtaat ttgtattgaa
      661 aatcataaca ataaatgatg ttgagtatgc tgtatttgct gctaatgaag gtacttccaa
      721 accacaacct catatcatag aaacgaaatc tggtactatt ccagaaggaa aacaactgag
      781 tttattaaaa gaatatctta agcagaatga tatttcccca ataaaaggag caacaacata
      841 ttggtgcatt gacaaggttc ttaagcttga ttcaagtaaa gaaaaaacta taagtgaaac
      901 aatccataaa caaaaatact tatctttaac tgaagaaaat attgagaaac agcataagtt
      961 tgtaggtgca agctctaatt atgggaaaga aggtctaata atacatgatg ttttgaatgc
     1021 atttcctctt cataatgatt taaatactat tgcgatgaag attgcggtaa ttgatgtaac
     1081 aaattcaaca catctttctc aatataagag caggttgtct ctatatgatt tggctaaagt
     1141 aattctggag attccaaatt ttgatgatcg gttggcaaaa ggagatcctc agttgataaa
     1201 tattatcgca aggaacattg gtgcagttaa tatgttctca tttgcatcca agtactgtac
     1261 atatcataat gtggaagtgt gtgggagaga tgattactcc atctttgatg gtatcgttaa
     1321 aaatactctt ccacactata tccaaggact aactacgaat aagattgata cgtggcgaag
     1381 aagttttgat tacgaggcat ttaacgaatg tgttggaaaa ctacttgatg aaaataatat
     1441 acatattcct tttagaagaa gaaagttaga tcacttcttg tggtatgcga ataggtagaa
     1501 tataagaaaa aggcatcgta aaagtgattc tggataaaat taatggggga ggaaataata
     1561 gtgggattat ttgattttct aaagaaaaaa caaggaaagg ttagtaaaca cgttgattat
     1621 caactggctt ctagtctatt tcgtactggt aaagtttttg ctgaaaaatt ggaagtggac
     1681 atatcaaatg tagatgagtt tcgtaaaact tttatcgctt ttgatgtgga aacaactggc
     1741 ctaaattctt cttcagatag aattgtagag attggtgcgg tgctatttaa agaaggagtt
     1801 ccaattcaat cattcggaac tcttgtcaat ccaaaagtta gaattgcagc ctcagcttcg
     1861 gcaataaata atataactaa tgaaatgcta aactctgctc caaatgagca ggaagtttac
     1921 ccccagttgg tagaattttt aggagatgca ctagatggaa aaatcactat gtgtgcacac
     1981 aatgcaagtt tcgattttgg atttttaagt aacacatttt ctagacttgg gtatgatgct
     2041 aaaattaagt atgttgatac tctgagtctc tctagaaaac atataaaagg cattgtaaat
     2101 cataagcaag agactgtagc ggaatatttc ggattaataa atgacactgc ccatagagcg
     2161 gaatcagatg cagatatatg cggaaagatt ttttggggtg ttttagatat tattgaggag
     2221 tcgttggaag aacaaaaaaa gcaaatagaa aagatgactc cagacataaa agaacttgaa
     2281 gcttgtgctt ttattcaaga tattattgag aaaaaaggat gcgacaccag ttggatcagg
     2341 tatcgaaaaa acagtaataa ttatgtcgat gtaacttgtc tatatacatt cttaaagttt
     2401 aagtttgcta agaagggaaa ttacatcatt attagaaaag atgctacaaa tggaattgat
     2461 ttacctatag aaccttgtac tgtaagtgaa ggcggtacaa caaatgtgcg agtctatttt
     2521 cgtagcccct ttgacttaac gcctctttca aattatattt tcagtgctta tagcgattgt
     2581 tataattcta tgaatgaata tatgagtgtt agtaattaca ctaaaaaaga agcagagcaa
     2641 agccttagta tgctgaaatc tatttcaaaa tcagcgatga aagagttatt attcgatgca
     2701 aaaaatcgtg gatatgatga gactgaagtt aacctaaata ttgaaaaagt gatatctaga
     2761 gaagatgtaa ttattaacgg gttgcataat cgagtttcat taaacaagat acgaaatata
     2821 gggaattggg agaaaggatt tgatgcaggt tatccatatt gggaacgtgg agaaactgct
     2881 aggaaaaatg gcaaagtaga tgaagctatt gcactttttg ataaagctcg atataacggc
     2941 tatgatgctc ctgcgctata tgattcttat gctaaagctt atcgaaaaat taaggattac
     3001 gataatgaaa ttctcattct tgatgaagga attatgcgta aaacacggca cgatgttggt
     3061 actttagagg ctcgtaggga taaggcaatt aagctattat ttgctaaaca agaggcagag
     3121 cggatagcta aggaaaaatc tgattttcta aaagcgaaca aaaaagagga tgcgattagt
     3181 gagcctagca agaagcgtgg aagacagatt attcaaatga ctgatgatgg aacaataata
     3241 aaagaattcg atactatagc ttctgctgta aaagaagttg gcgttaactc aaaaagtatt
     3301 agggatgctg caaatggagt tcaaaaacat gctggaggat actactggaa atacaaagat
     3361 tagcagataa tctaagataa cctaggatct tcttaataga tacccgtggt gctagttaat
     3421 tttaatatcc taaagaatat ctcaaagttc cttcaaaacg tcgttgtgct cgacttaata
     3481 gaacactgta agccagtaat atgctttcaa atctactctc tagcccttta acagaacgtg
     3541 agttgaaatt ttgacaacct aatttttcta aggaagaaaa aacagtccca actgtttttc
     3601 tttgttttcc aagtaagctg tggtctagtt tttctgattt atccatgttt ttacgtggcg
     3661 gaatggatat agtaatgccc
//
LOCUS       DBGZHO010000121         3605 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.128, whole genome shotgun sequence.
ACCESSION   DBGZHO010000121 DBGZHO010000000
VERSION     DBGZHO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.128"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1253)
                     /locus_tag="ACN3HL_002791"
     rRNA            complement(<1..1253)
                     /locus_tag="ACN3HL_002791"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(1926..2282)
                     /locus_tag="ACN3HL_002792"
     CDS             complement(1926..2282)
                     /locus_tag="ACN3HL_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HHC8007578.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(2296..2706)
                     /locus_tag="ACN3HL_002793"
     CDS             complement(2296..2706)
                     /locus_tag="ACN3HL_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HHC8007579.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            2925..>3605
                     /locus_tag="ACN3HL_002794"
     CDS             2925..>3605
                     /locus_tag="ACN3HL_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HHC8007580.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAIYQKG
                     KRIMVPLPV"
BASE COUNT          993 a          799 c          660 g         1153 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg cctttcaaat caaaaccatg cggtttcgat tgttatacgg tattagcacc
     1081 tgtttccaag tgttatcccc ttctgatggg caggttaccc acgtgttact cacccgttcg
     1141 ccactcctct ttttccggtg gagcaagctc cggtggaaaa agaagcgttc gacttgcatg
     1201 tattaggcac gccgccagcg ttcgtcctga gccaggatca aactctcata aaaagttcga
     1261 acaatcttgc gattgttaag ctcaatttgt ttgctagcat attgcttgct tgttaaaaaa
     1321 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
     1381 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
     1441 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
     1501 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
     1561 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
     1621 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
     1681 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
     1741 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
     1801 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
     1861 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
     1921 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
     1981 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
     2041 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
     2101 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
     2161 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
     2221 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
     2281 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     2341 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     2401 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     2461 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     2521 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     2581 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     2641 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     2701 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     2761 ccaattatta gctaataaaa tataaaaaaa aacccgtggt gctagttaat tttttcctag
     2821 aggaaaatgt ctaaacatgt tggtaaatca acaaaaaaac gcatatagta gtctcaaaac
     2881 tcccaagaaa tgaggactat ttaacaaact acgatggtta cgtcgtgaca actgaacatt
     2941 ttgacttagc caatcctgtt actaaagtcg atgatatccc cgattatgaa atgtacagtc
     3001 aaacaatcga tagcttaaat aagcgttttg gcaatcgtgt tttaaaaggc atcgaaatcg
     3061 gttacatcgc ttctgaaaag gatcggatca tcgactattt agccgataaa gattacgatt
     3121 taaaattact cagtgtgcat cataatggtc aatttgatta tttagatgac gaagtcaaag
     3181 atatggatcc tgctattgtg attcctcagt attttgcaca actttcagaa gcactagttg
     3241 ttatagaagc agatgtcttt gctcattttg actatggttt tcgggtattt ggtctatccg
     3301 ttgctgaatt taaacaatat gaagcgcagt ttttaccgat tctagatcaa gtaattaaaa
     3361 ataaattggc attcgaatta aatgctaaga gcgcttactt gtatgacaat ttagcgttat
     3421 atgaatatgt catcgattta tatctttcac gtggtggtac cttgtttagt gttggatcag
     3481 atgggcatta ccttgaacat ttccgtttcc atttcgatga tctttttgct ctgttaaaag
     3541 caaaaggtgt gacggaatta gcgatttatc aaaaaggaaa gcgaattatg gttccattac
     3601 cagtc
//
LOCUS       DBGZHO010000122         3199 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.129, whole genome shotgun sequence.
ACCESSION   DBGZHO010000122 DBGZHO010000000
VERSION     DBGZHO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.129"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            677..763
                     /locus_tag="ACN3HL_002795"
     CDS             677..763
                     /locus_tag="ACN3HL_002795"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HHC8007581.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1065..1289)
                     /locus_tag="ACN3HL_002796"
     CDS             complement(1065..1289)
                     /locus_tag="ACN3HL_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007582.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRS
                     LEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1655..1939
                     /locus_tag="ACN3HL_002797"
     CDS             1655..1939
                     /locus_tag="ACN3HL_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007583.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1942..2358
                     /locus_tag="ACN3HL_002798"
     CDS             1942..2358
                     /locus_tag="ACN3HL_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007584.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(2495..>3199)
                     /locus_tag="ACN3HL_002799"
     CDS             complement(2495..>3199)
                     /locus_tag="ACN3HL_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HHC8007585.1"
                     /translation="ELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLKKVRFS
                     FEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEINKTKK
                     FVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIE
                     EFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSS
                     LTSDLPKISLRNWLEE"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct ttaacaacca
       61 actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga taaaaagttg
      121 ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta ctcagataaa
      181 aagttgttag tacccttctg tatccgttgg gagagtaagg ctcaactgcc ccctaaaaag
      241 ggttctaaaa aatctttaaa aaataaataa aataaacgcg cgcgcgcgag caaaatttcc
      301 cgccaaaaaa tcacccactt tttaaaataa acaggttcgc gcatgatatt aaactgccaa
      361 tctagctccc tatggtcgct gtaagaagga gtgatcgcta cgctctcaca ttttacttgc
      421 agcagtcgcc tttaggctcc ttcgccaaaa ataattcatt agggactcct ttgtggcgtc
      481 ctgagagctc gtctaagccg ttctaagaca agattcgata aaaactatgt ccttcgttct
      541 aaagcgcctt acaggcggtc agggcaagcc ctaacaaccc caaggcaata aaaaacttag
      601 gcttattttt gcttttttat tgtataattg attgtcgcct atccgacagt cttgcgactg
      661 gaaggaggtg tgtttcgtgt tcactaactt tatttgctcc cttcttgttg ggcttttaag
      721 cgctttgttc agttactggt tgaataaccg aaacaagaag taaaacttaa ttaaggcgac
      781 tcagcccaca aaaaaagccc cagagaatcc gacctctctg gggctttcgt gtgtttcgtg
      841 ttcacttatt tgcaatcaaa ttataacaga aataaatatt tatttcaaaa atatcctaca
      901 aaagtctaaa atccgtaatt atttcttata tgcaacattt acaaataaag tcgctctgag
      961 agctcgtatt tttcgattta agacgtttta tttagttttt ggtgtatttc attggtccaa
     1021 gctaaaaaac tcttagaagc gattttagag ccatttaaac ccacttaatt atattctcca
     1081 tgaaattcgc tccatgcgtc aaaagctgcg tctgaaattc cgccgtcttc gttcactagt
     1141 tgcattaatt tttccaacga tcgttttctt tcgggtgtca tatttttata ttccaacaat
     1201 ttttcgtctg ttaaatcgaa cttgattgct tgaattgctt gctctaattt ttctaagttt
     1261 tgaaaatatt cgtaaggaaa tttttccatt ttttctttct ccagtctcac aatttttcta
     1321 gaaataaaat cacttctttg ccgtctatac tctcaaaaaa aatgtcgttt gaaaaactaa
     1381 ataaattttt gatcgtgcat ttttaaattt ggttatcgat tacacgtgca gcactccccc
     1441 ccgaatttta aagagcataa ggaaacgtgt acccactttc taaaaaaagt gggtagatag
     1501 gctgtgccta tcacgtttct cagaaaaaaa tttgatatca ctttttcgcc atcgtgggta
     1561 gcttatgtat agcattttgg caaaaaacag ctatacaaat atagtatttg tatggtatac
     1621 ataaattata cataattgca aaaggagatt ttttatggac attttagttc ggaatattga
     1681 tccaaagttt gttgcaacaa tagacaaacg ttgccaagaa ctcacgaata aaacaggaga
     1741 aaaatggagt cgaaataaat atctaaaagt tttaatcgaa agtgattttg accgtcaact
     1801 tacgacttac aaaaaagacc aattcgattt attgctcgat aaatttattg ctatccaaac
     1861 agaaaatact caaatattaa gcgagtatgt ctacacaaat aatcaaatca ttgaaatgct
     1921 tatcggagga atgatataac catgagaaaa acttctgtcc aaaaacatgt tactttgtac
     1981 cctagtcatg ttgacgtttt agattccatc atcgaaaaaa atccagatat caataactac
     2041 tcggaagcca ttcgcttttt atgtatgagt tatgaacccg ataccaacac gaccactacc
     2101 agcaatcagg caaaactaaa tgctatggga aaagaaattt ccatcatgac tgaaatcatc
     2161 gcagaatttg ctgatttata tctaaaagat acaggcgttc ttattggcac aaattctaaa
     2221 gtatatcaag aagtgaaaga aaaaatcgaa gctaaactaa atccatcaaa tcgaaatcga
     2281 ccaaagaatc atcaaaaaga aaccagtcaa acagtcactt ctagaaattt cgacccaaca
     2341 aattttctaa aacgataaaa aacagatagg agttattcct atctgttttt tatttagaag
     2401 ccccatacaa tatgctagaa tgtactagca atcttagtcg gttgtaaggg acttgtctac
     2461 ttgcttaatg taaggggggc gagttctttt ttatttattc ttctaaccag ttacgcagag
     2521 aaatctttgg caaatctgac gttaggcttg aaaaagtaaa ttctaatttg gcgattttat
     2581 tgcccttttt tgcttttatt tttgtgactt taagatcatt gaagtatttt tttagttctc
     2641 gtaatgcagg atttaatact ttttgatcaa tgttacccat ttgatagtat tctgggatat
     2701 ccattaagct cctaaactct tcaatacgaa ctacataata accagtagaa cggtactgca
     2761 taagcagtcg gaatagagtt tttgcatacg tagaacgcaa cgacgtgaaa gcagataatt
     2821 caaatctact aaattcagct gttaaaccat taataatata ttctaggtcc ggattaacac
     2881 tgacttcaac aaactttttt gttttattga tttcaaaacc agtaaacaaa acaaagtagc
     2941 gaatagaatc ctcatcttca gtacggtaag taagattaag catatcttta tagagctttt
     3001 ctaaatcacc gacaaaggct tttgtagcag tcatcttata atcacttaac tcttttaatt
     3061 cctcgaaaga aaatctaact tttttcaaac cacgatcttt catacgagcg cataatgcaa
     3121 aaaataaatc catctgctta gcattgaaat ttttcagcgg tactaaattc aattcatttt
     3181 gatatttgac tgttaattc
//
LOCUS       DBGZHO010000123         3176 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.130, whole genome shotgun sequence.
ACCESSION   DBGZHO010000123 DBGZHO010000000
VERSION     DBGZHO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.130"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(62..286)
                     /locus_tag="ACN3HL_002800"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACN3HL_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACN3HL_002801"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACN3HL_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACN3HL_002802"
     CDS             2092..3132
                     /locus_tag="ACN3HL_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HHC8007586.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT         1175 a          446 c          461 g         1094 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaa
//
LOCUS       DBGZHO010000124         3002 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.132, whole genome shotgun sequence.
ACCESSION   DBGZHO010000124 DBGZHO010000000
VERSION     DBGZHO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.132"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..861
                     /gene="mobL"
                     /locus_tag="ACN3HL_002803"
     CDS             <1..861
                     /gene="mobL"
                     /locus_tag="ACN3HL_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HHC8007587.1"
                     /translation="HIHIHFAVVEKENTRKPYTEIENGVSYIVPKGKRRQATLDAMKT
                     NYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYDRHAMNLLNEVYK
                     TLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQISKALKEEAKSL
                     YGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVNQMQSIYNERSFR
                     TLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEEKYHASKAYEEQQ
                     RRIQMEQERQ"
     gene            873..1208
                     /locus_tag="ACN3HL_002804"
     CDS             873..1208
                     /locus_tag="ACN3HL_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007588.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            1355..1549
                     /locus_tag="ACN3HL_002805"
     CDS             1355..1549
                     /locus_tag="ACN3HL_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007589.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            1581..>3002
                     /locus_tag="ACN3HL_002806"
     CDS             1581..>3002
                     /locus_tag="ACN3HL_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007590.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT         1230 a          455 c          630 g          687 t
ORIGIN      
        1 catatccata ttcattttgc agttgttgaa aaagaaaata cgcgtaaacc gtatactgag
       61 attgaaaatg gtgtgagtta tatcgtaccg aaggggaaga gaagacaagc aacattagac
      121 gcaatgaaaa ccaattatgt acatgagtta gaacgtttct cttatgaaaa ggatcgaatg
      181 atcggtatgg agaaacgaaa tttattgaca cgaaaaagtg atttgcgtaa caccttaaca
      241 aaagtagtaa aagaaccagc acgttacgat cgacacgcca tgaacttatt aaatgaagta
      301 tataaaaccc tacctgaaaa acgttcggaa tggaattatg gagatgaaaa tcgaaccaag
      361 ctttcaccat ttacaagggg aaaacttgat gagttaacca aatatgtttt aacaaaagaa
      421 cctggatatc aagaatatat acagatttca aaagcattga aagaagaagc caaaagcctt
      481 tatggggaaa gcaaaagaga aacaaagaat gcagaaaaaa acgccctctt tgatttaaaa
      541 aagcgcacag gaaatgcgat tttaacagaa ctgaagagac aggatagtca aataaaacca
      601 ttaatagaaa gtgtcaatca gatgcaatct atttacaatg aacgatcctt tcgaacactc
      661 aaacagttgc caacaaatga atacaagtat agttatcaag aattcgtaaa gcgtaggaaa
      721 caattccaac aaagagttgt cacgcagcga agcttgcgtc aattaaatcg aacaattaat
      781 gcacatgaag aaaaatacca cgcaagtaaa gcatatgaag agcaacagcg aagaatccaa
      841 atggaacaag aaagacaata ggaggaagag aaatgaaaca atatttagat caatggaaag
      901 tcatagaagg atcactaaaa gaagaacgaa tcgaacaact tcctgattgt ttagaaaaag
      961 agcatttgtt tcagataagc gaaatgttga gaaacgaaca gtttgatcca aatcaatttt
     1021 tagttgttga gtacccagct actggtgtgt attgttgtaa tcatgtgaag ggtgaaaaat
     1081 attttattat tcaagaatac gaaggtaagt tagcgcctta ttatactact tgggaaataa
     1141 atgaagaggg aatcaataat ttcccatgtg aaagcattga agagtctatt tctctcacgg
     1201 aatgttaaat aaatagagac gtaaaagagt cctgaacgtg attgtccagg actctttttc
     1261 aatgaattgt tttccgccaa ttcactgagt ggtgcgattc aattttatta tatcaaaaga
     1321 aagtgagatt ccaaagtgaa gggaggaaga agaaatgact cagacaacga ttggtgttgt
     1381 ggttgaaaaa agcagggata atctcgtttt tgtgacagaa attcaaacag gtagagcttt
     1441 tgtagtcaca gacaaagctg caaaagcgta tcaaaatggc aatattttaa cgttaaatct
     1501 gactacgaag atgttcgttg atgcagtaga aaattatcca tttgtttaga caaacgatat
     1561 tttacaagga ggaaacggac atggcagaag aaaaagaacc actagataat agtcggttgg
     1621 gaaagtccaa aagaaaatta gtacggttgc aaaacgaatt aaataatcaa tttcaaaagc
     1681 tatttgatca ccaaaaattg acaaatgggc aaccaatgaa tgacaaacga aatggtcgtt
     1741 catggtttaa ccagcaagaa aaaatagaaa ataaaataca aagtttgaga gaagagatca
     1801 agcaacaaga aaaacaggta gaaaaacttg aaagacaaga agagctaaag gaaatgggct
     1861 ataacaagta cggcggactg gatatgacga tcgataatat tccaagaatc aaagaagaaa
     1921 tcgaacgctt tgaaaaaggt gaatcgactt tttcagccgc cacgatccga aaatatcaac
     1981 ggaagttgga aacattagaa cagctgaaag aaaaatcaga aaaaggaaaa gaaaatatcc
     2041 tccctgaagt acaagcgatc attgacagcg gacgagtgac gcaatggaaa aaaaatccaa
     2101 ccatttattt tttgaaaggc tatcgaaaag ttgctttaga actgaatgaa aacgggggat
     2161 ttgaggaatc aaaaaaatac caagccacgt cggaagagga aaaagcagct gttcgtgaat
     2221 tacttgaaga ggctgcacca actgattctc tgaaggagaa agaaaaagat catttctatc
     2281 gagtagaatt caacgaaaat gatccagaaa aaggattgaa aagttatggt ggggagatcg
     2341 taacattcga attgatcgat caacttaaaa cgttggataa ccaatacgct gcagaagcag
     2401 gttattataa attctatttt gaagaagtga agaacggaga agtagtagat cagatccgaa
     2461 tggatctagg ggatggcgtc aacagtaatc accccatcta tttagagtta gcaaaattgt
     2521 gcgaacaagt acctgagaag gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag
     2581 aacaaatgca gtcgaaagaa acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag
     2641 aagagatcaa acaagaagtt aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc
     2701 atacccattc ttctgaagac gtcaaagaac ttttgaactt tatgtctcgt tttccagaac
     2761 gatcctttag aaatcaatta ttgattgagg aacaatttcc aggtgcaacg gcttgtttag
     2821 gtcgtgccgc gttgaaaaaa gaaggaatct atatcaaaaa aggggaacaa gggaacaaga
     2881 tctttgtcag aaaaacggtc aaaggatttt atgagaaagg acgtggcttt gttcgagaaa
     2941 cagaagctac accagaagat aaaaaacgaa tcgaaagtgg tcaaatcgaa gtgatcaaaa
     3001 aa
//
LOCUS       DBGZHO010000125         2998 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.133, whole genome shotgun sequence.
ACCESSION   DBGZHO010000125 DBGZHO010000000
VERSION     DBGZHO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.133"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            101..481
                     /locus_tag="ACN3HL_002807"
     CDS             101..481
                     /locus_tag="ACN3HL_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HHC8007591.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            463..1377
                     /locus_tag="ACN3HL_002808"
     CDS             463..1377
                     /locus_tag="ACN3HL_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HHC8007592.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            1337..1615
                     /locus_tag="ACN3HL_002809"
     CDS             1337..1615
                     /locus_tag="ACN3HL_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007593.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            1622..2311
                     /locus_tag="ACN3HL_002810"
     CDS             1622..2311
                     /locus_tag="ACN3HL_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007594.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(2432..2518)
                     /locus_tag="ACN3HL_002811"
     CDS             complement(2432..2518)
                     /locus_tag="ACN3HL_002811"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HHC8007595.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
BASE COUNT         1090 a          575 c          583 g          750 t
ORIGIN      
        1 ccctttagtg agctttagtg agctttactt attgtacctt tttaggtaca atggtattgc
       61 gaacgatacg tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaata
      121 tttggctagc aatcattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt
      181 tcgagtgagc gaatccgaat ttgcaaagct gaagcagtca gctgaagctt tgcaaatgag
      241 tgtgccggct ttcgtgaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc
      301 gccagacatt gctcaggcaa tcgcgcgcga tttagccaaa gctggcggga atatcaatca
      361 aattgccaag tggtgcaaca cacaccaaca cgacgttgat cctggcgacg cccaacgctt
      421 atccgaaaac ctaaaaatca tgcaaaagga gctacaaaag atatggcaac agttaaagta
      481 agccgaacca cttcttgtag ccgagcgatc aattacgccg aaccacgagc aaccgtcaaa
      541 acagggataa actgtgacat tgattatgcc aaaagcgaaa tgaaacaaat tcgcatgctg
      601 tatggaaaag acgatcgtgt acaagcacac ttattgatcc agtcttttcg accaggagaa
      661 attaccgctg aaaaagccaa tcaactaggg gcagagtatg cgaaaaaaat agcccctgac
      721 caccaaatcg cgatttacac acatacagac aaagaccata ttcataacca cattgtcatt
      781 aactccgtca atctggaaac tgggaacaaa tttcaagccc atggtcaagc atttttaaac
      841 aaatgttatg acctaaatga cgagatttgt cttgaacatg acttaacaat cactgaacga
      901 gggaagaaac ccgaaaaacg aaccatgtct gaaatcaaat taaaagaaaa aaatgaacct
      961 gtttggaaag acgaaattcg gtttgcgatt gatcaaacaa tgaaaaacaa aaaaactcga
     1021 acgtataacc aattttgtga ttctcttaaa acattcggca ttcattgctt gaatcgtggg
     1081 aaaaatttta cttacgaatt gatccacaaa aagaaaaaag tacgatccaa caaactagga
     1141 aaggattacg aaaaggagac gattttacat gagctggaca gacgagaacg agcctacaat
     1201 caacaacgaa ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcaaaagaa
     1261 gtacgaagag aacaacgaac tcttacgact gaacaaccgg aaattagacc gactcgaaga
     1321 aaccatgacc aacacgttga aagaggagca gactaccaac aagaattatc gttctaaaac
     1381 gttacaagac atagaaaatg aaataaagaa acaacgtgct tttcttgcac cttataccaa
     1441 agaaagaata caaactacaa ttgattcaca agtcaaaaaa ttccaccatg cgctattaaa
     1501 ccagcgaaat aaagaacaga aaaaagtaat tatgcagcga tcaatggata ttcttgcccc
     1561 cttatgttgc ttaatcatga cactgttagc cttttggctg gtatggggag aataaataga
     1621 aatggcattc tatttaccct atctactcat ttttgccagt attttaggaa ttatttggct
     1681 tagctataag gcttatcaaa caagatattc attaaaaggc tctaaaattc gatttaagag
     1741 gtttttattg ccaggggtta tatttacatt atcaatcgtt ttaagtggtt tattcggcgt
     1801 tttagaggga aataaacgta tttcaagaag tattttatta ggggatatca ctcaaaagta
     1861 tgaagcagca tgtgataaaa agaaaaagga gcaagtgtta acacaaaaaa tggaagagtt
     1921 taccacttgt tatgaggaaa tgaacgatat ttttgtgaat caagaaaaac gtttgacgga
     1981 taaaaacatg gaaaaactca ctcgtcttta tcaaaacttg ccagaaaaac agcaaaaaga
     2041 ggttcaagac aactatgagc gaaccaaaaa agacgtgcaa tattttaaag atacgcagac
     2101 agaagaagct tgttataatt tattcagtga tacaatccct ttttcaacta gtgaacagga
     2161 acgaaaagaa cggcaacaat cagttaccta cgaacgttat aaagcactgc ttcagcaagc
     2221 aacgaacata caaaatccaa cgaaaaaaga aacggcatta aattatctaa aaagtgtcaa
     2281 ggaatggtta gatcagcaac agcaaaattg aatttgatcg gcaatcatgt taaactaaac
     2341 atgcaaatga tcaaacatta gatacacgaa agccccagag aggtcggatt ctctggggct
     2401 ttttttcagg ttgatgtcgc ctttattgat tttacttctt gtttcggtta ttcaaccaat
     2461 aactgaataa agagacacaa acttctataa gaagggggca aatgaacaat tcaaacatta
     2521 gatacacctc cttccagtcg caagactgtc ggataggcga caagttatta tatcttaaaa
     2581 aattaaactt gtgtggtgtt tttaagtatc gcttatttta gggttgttag ggcttgccct
     2641 gaccgcctgt aaggcgcttt aaagctagat aaggattttt atccaagact gtcttaaaac
     2701 ggcttagata agcattcaga accgctcaaa ggcctcttta ccaacatgtt tttagcaaag
     2761 gagcctttag gcgactgcgc agtacaatgt gagagcgtag cgatcacacc tttttggcga
     2821 ccgtaggaag caaggttttg gattggcagt tttgaaaaat gcgcgaacct gtttaaagaa
     2881 aaaagaagtg gtttttaggc gggaaaatta gcccccctct ttttatatct ctttttaaac
     2941 ctctttttaa acctctttac cgtaagctgt gtccttactc taccaatgga tacagaat
//
LOCUS       DBGZHO010000126         2730 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.135, whole genome shotgun sequence.
ACCESSION   DBGZHO010000126 DBGZHO010000000
VERSION     DBGZHO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.135"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(40..1416)
                     /locus_tag="ACN3HL_002812"
     CDS             complement(40..1416)
                     /locus_tag="ACN3HL_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HHC8007596.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1544..2632)
                     /locus_tag="ACN3HL_002813"
     CDS             complement(1544..2632)
                     /locus_tag="ACN3HL_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HHC8007597.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
BASE COUNT          854 a          557 c          437 g          882 t
ORIGIN      
        1 tttattcaag caacacgtct ttcataacca agtttccaat tatcttcttg gctcgtcatc
       61 ttcgaattct tttctgaagt atcttcgttc ttcttcaggt tccgcttctg tttcttccgg
      121 atcatgaaaa atgacacgga ttttaaggat tcgagaacct tccatttctt cagaaaccag
      181 cgtaatatta tcgacatcaa acgataactt ttcgccttca tccggaatca tgcctaatgc
      241 tgtaatcaaa taaccagcca tcgtatctac atcactcata tgcagatcac tgtcaaaagc
      301 ttcattgaac tcatcaatca gcatacgtcc ttggatgata tattcgtgtt catcgatttt
      361 ttcataaaga ttctcaactt catctgattc atcatcgatt tctccgacga tttcttctaa
      421 aaggtcttct agtgttgcta acccaacgac gccgccatat tcatctaata aaatagccat
      481 ctgattctgc gtctttttca tttcatataa cagatcatca ataaagaccg tttcaggaac
      541 gaataaaggc tcctgcatga ttttcttgat atctaaatta tcaaagccga atttatgggc
      601 agcttttagt aaattctttg tatgaaggat tccgactact ttatctttgt cttcgttata
      661 aacagggatt cttgaatagt tttcggataa aacttcattc acattttctt ccacagtgtc
      721 gttgatatca atcataaatg catccgttcg tgggaccatg acttctcggg caactttcgt
      781 atcaagagaa aaaacccctt ggagcatttc taattcttca ttattcaata cgccttcgtt
      841 ttcaagcata taacgcattt catctctggt catttttgaa tcttcatcat caaaagtcat
      901 cggcgtgata cgcgccaata aacttgtgga agcagaaagc agccagacga agggcttagc
      961 tactacacca atcaagcgta tcagccctga agtgaacttt gcgacttctt ctgatttatt
     1021 taaagcaata cgtttagggt acaattctcc aaaaacaatc gatacatagg tcaaaatagc
     1081 cagcacaatg atatttgcaa tattttttgc cgctgtgccg ccacctaata ccggagctaa
     1141 ccgttccgat aaagtattag ctagtgaagc accagacaaa atgttgacca aagtgattcc
     1201 tacttggatt gtcgatagga aattatttgg attctgcaat atttttaaaa gcttttgaga
     1261 tttcacatct ccttcatcag ctttttgctc gattcgattc ttattgatcg aaacaacagc
     1321 aatttcggaa gctgctaaaa aagcattgat caatgtcaaa acgatcaata ataaaatctg
     1381 cgctaacagc gactgactct cagggtcagc attcataatc gcattctctc cttataaaat
     1441 taatttttag tttacgatag aaaaaaacgt ggcactatag ccacgttaaa atggtatcac
     1501 aaagcaattt tctttgcaat aaaaacaagt gtactaaaac tacctacgag gtcgtagcaa
     1561 ttttcttctt gttttcattt tgcttgtctt ctttgacgat tttgattata taggaaatga
     1621 tcgtcttgca gattgcgtaa aaaggaacac ctaagaagat accaagcaat ccggcaatat
     1681 ttccagctac tagaagaacg ataatgatcg ttaatggatg gattttcagt gatttcccaa
     1741 ttacattagg ataaatgata ttcccatcca actgttggac gattagcaca accacacaac
     1801 aaagtaatgc ttttaccgga tcattgaaga ctgttactag aaatgcaggt gctagtccta
     1861 gataaggtcc taaatatgga attaggtttg tcaatcccgc aatgacccca aataagaaag
     1921 cataatccac accaattacc atatatccta aaaatgtgaa ggtaccaacg aataaacatt
     1981 cgattgcttg tccgctaatg taattagcca atgttttatt cagttgcccc aataactcca
     2041 caatttggtt tcttcttttt tctgggaaaa actgttggat gtttggcact agtttttctc
     2101 cgtctttcaa catatagaac aagatgaatg gtgctgtaat gattactacg gttgccgaag
     2161 cgatcgttcc aacgatcgaa cctaaactat tggatactcc actaaggaat tgctgaatga
     2221 ttgtcccgta agaaatgtct aattgctcaa aatatttatt gatatctact tccttgaaca
     2281 aaggcaattc ggctacctct tttaaccagc tttctacctg tttgatgaaa tcaggcatat
     2341 tagatgccaa tgaggaaatt tgctgtacta gacttgggat gacactaagt aaaatccaaa
     2401 taattgctgc aactaaaagg agcagcacaa ttgcgacagc ccatattctt ttgatttttg
     2461 ctttcatcaa cagcttgaca ataggattca ataaatagta aagaaagcct gcaatcagta
     2521 caggtgcaaa taacgtggaa aaaaatgtcc cgatcggttc gaaaataaag tttatttctg
     2581 atgaaatcat gatcaatgca gctatgatca ataattcaag cgaccaaaac attagtttag
     2641 actgtctaag tttttcaaac aatagatttc ctcctttctt tcttactagt atatattata
     2701 ttcgttaaaa attcttttat tcttttttta
//
LOCUS       DBGZHO010000127         2694 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.137, whole genome shotgun sequence.
ACCESSION   DBGZHO010000127 DBGZHO010000000
VERSION     DBGZHO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.137"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1444
                     /locus_tag="ACN3HL_002814"
     CDS             <1..1444
                     /locus_tag="ACN3HL_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HHC8007598.1"
                     /translation="SFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCW
                     LPYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVF
                     LFSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFS
                     IACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIIL
                     KQKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLS
                     KKDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIK
                     IYTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDAR
                     DFFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLA
                     LGLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            1431..2633
                     /locus_tag="ACN3HL_002815"
     CDS             1431..2633
                     /locus_tag="ACN3HL_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007599.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT          771 a          481 c          465 g          977 t
ORIGIN      
        1 ttctttttta tttttacaat cgatttattt atcaatgcca aaactggaaa cattttttac
       61 tgctcaaaac acacaggctt tctcttcaag aaaatatttt ttattcttta ctgtcttttt
      121 agttctgtgt tggcttcctt atctgttggc attgtatcct ggagtggttt tgcctgattc
      181 gttaagttcg gtcgcccaat ctatgggtga tgttcctata agcaatcatc atccagtctt
      241 attcacctta ctggtcaagc tatttgttca tgatttacca actgatacga tcaatcacgg
      301 tgtattttta ttttcgattt ttcaaacatt gataacagct tcagcgataa gttattctct
      361 ttgctggctg ttaaaaagaa acatccattt ttttccggta ctcattagtt tatgctattt
      421 tgcatttgca ccggtttttc caatctacgc cttgaacatg caaaaagata ctttgttctc
      481 tatcgcttgc tttttatttt ccttagcggt ttttgacttt atttttcaac gagaaaagcc
      541 aacgattctc aatcagattt acgtaatcat ccttgcttta ctgaccacct atctaagaaa
      601 taatgggatt tatgtagtaa ccggcacagg tttgatttgc ggcttgatta ttttgaaaca
      661 aaaaaggtat caagcattct ttcaagtggt gctgggttat acagtgattg ctggactact
      721 catccacccg ttgatggctc gttatgctat tcctacagaa actgctgaac aattaggtgt
      781 tcctttgcag caaatttcta gaactattgt tatggatggt gacttgtcta agaaagataa
      841 agcattcatg aatcagctac tcccgataaa agattatgaa gcgtattctc ctagtcttgc
      901 agactcaatc aagtggcata aaaattttaa caatgagttt ttgaatacac ataaaaaaga
      961 atttctatca ctatgggcaa gaaatttacc aagtaatata aaaatctata cagatgctta
     1021 tattttagaa acgttcgggt tctgggtacc tggtacaaaa aatagttacg gctttttaga
     1081 tactcgtgta aacacgaata attatggtat gaagcaagta gatttgattg aacatcttac
     1141 tggattgtca ggaatgaaaa aaatcatcga tgctcgtgat ttctttggtt ccggcacatt
     1201 actgtggtta gctatcggca gtgcactttt agcaatcttt aagaaaaaat atcggtattt
     1261 actccttttt cttcccggta tgcttgtttt tgctactatt atgattgcta ctcctgtggc
     1321 ttttagttta cggtatgtgt ttgttttagc attaggtcta cctgtttata tcctctctcc
     1381 ttttttacta gataaaagag aaaaaatgaa aacagatata ggagatactc atgaaactat
     1441 ttaaaaagat attttttgct tttgttctct tgatcgctag ctattgcgta ctactgacaa
     1501 ttactttttt cattccgcag cactctattg aatcgaatgc agaaaaatct ctacagatgg
     1561 ttgaaaaaga aggaatgtat ccttctatca atcaaggaaa tatgctaggc actcggttag
     1621 ataattttac tgatcatttg atgatacgaa aaacaaaagc agatcctgaa ttgaactcct
     1681 tggagaacgc gatgtctatg gcggattatc cccgttattg gcatggttat cagctttttt
     1741 tacgaccttt actgctaggg atgagtttgg ggagtattcg aatgatttac gcagccattc
     1801 tttttctgct gattggattg acgagctact ttttaaccaa gtgtagcgac atctatttaa
     1861 cgacagcctt gttgatttcg cttgctatag gaaatgctgc aacctttttc ttcagtatgc
     1921 aattttcaaa tatttggatt ttgactttat tgtctgtatt actattttta acaaaaccac
     1981 aactctccaa caccaaccaa caattattct tgtatttctt tgtcattggt tctttagcta
     2041 acttttttga cttgttgaca acaccggtca tctcttgggg gatacctgtg atcattattt
     2101 attatgtaac aaataagtat ttaatggata aacgcagttc attgagcaaa caagtaggca
     2161 gttttgtttt taccggtatc ttttggggat taggctatgg tttgacatgg gtggctaaat
     2221 ggatcctatc atcgatcata ttgaacaaaa acattgtaaa agatgcaatc aaccaaatcc
     2281 tctttcgaac ggaaggaaac gacaaatacc cgttgcatcg attagagatg ctgaaaagca
     2341 atattagatt gatgtatcca aaagtagcaa tattattgct attgattact tgtcttgttt
     2401 ttctctattt tgcttatcgt aaacgaaata gctggcgtcc gttccaactt ctagttttgt
     2461 ttgttttagc tgctgtaacg ccgtatattt ggtacaatat tttagctaat cactcacaga
     2521 ttcattattg gtttacgtat cgtacgcaaa tcatcacaag ttttgctata cttagtgctt
     2581 tcgccttttt gatccctcct gagaaatcaa aagacgaact aaattacttt taagaatacc
     2641 gatgtactaa ttcattttta aacataaaaa ctccagctgt cagagatagc cgga
//
LOCUS       DBGZHO010000128         2435 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.139, whole genome shotgun sequence.
ACCESSION   DBGZHO010000128 DBGZHO010000000
VERSION     DBGZHO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.139"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..382
                     /locus_tag="ACN3HL_002816"
     CDS             <1..382
                     /locus_tag="ACN3HL_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007600.1"
                     /translation="RITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDNPYSQFLI
                     TVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMT
                     VNQICEITNVSRASLYRKLSEVNN"
     gene            596..1291
                     /gene="vanR-A"
                     /locus_tag="ACN3HL_002817"
     CDS             596..1291
                     /gene="vanR-A"
                     /locus_tag="ACN3HL_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HHC8007601.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1269..2423
                     /locus_tag="ACN3HL_002818"
     CDS             1269..2423
                     /locus_tag="ACN3HL_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HHC8007602.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          839 a          437 c          515 g          644 t
ORIGIN      
        1 tcgaatcact cgtagtacac aagatctatt tgaattaatc gataacatac gagataaaaa
       61 ggcaagttta aaatcactaa aagatacatg gcttgattta tcagaagata atccatacag
      121 ccaattctta attactgtaa tggctggtgt taaccaatta gagcgagatc ttattcggat
      181 gagacaacgt gaagggattg aattggctaa gaaagaagga aagtttaaag gtcgattaaa
      241 gaagtatcat aaaaatcacg caggaatgaa ttatgcggta aagctatata aagaaggaaa
      301 tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat tatacaggaa
      361 attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata tttttaaaga
      421 agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc cctttgataa
      481 aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc ttataaattc
      541 ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga taactatgag
      601 cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg aattatactt
      661 aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat tggaatgtat
      721 agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca caagcggcct
      781 tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc tgaccgggaa
      841 agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt atataacgaa
      901 gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc gatacaaaaa
      961 attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc ttgtcattaa
     1021 tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc ccaccgagtt
     1081 ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg agctgctatt
     1141 tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca ccgtgcatat
     1201 ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata taaaaacggt
     1261 atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa ctagaacgaa
     1321 aactttacat gtatatcgtt gcaattgttg tggtagcaat tgtattcgtg ttgtatattc
     1381 gttcaatgat ccgagggaaa cttggggatt ggatcttaag tattttggaa aacaaatatg
     1441 acttaaatca cctggacgcg atgaaattat atcaatattc catacggaac aatatagata
     1501 tctttattta tgtggcgatt gtcattagta ttcttattct atgtcgcgtc atgctttcaa
     1561 aattcgcaaa atactttgac gagataaata ccggcattga tgtacttatt cagaacgaag
     1621 ataaacaaat tgagctttct gcggaaatgg atgttatgga acaaaagctc aacacattaa
     1681 aacggactct ggaaaagcga gagcaggatg caaagctggc cgaacaaaga aaaaatgacg
     1741 ttgttatgta cttggcgcac gatattaaaa cgccccttac atccattatc ggttatttga
     1801 gcctgcttga cgaggctcca gacatgccgg tagatcaaaa ggcaaagtat gtgcatatca
     1861 cgttggacaa agcgtatcga ctcgaacagc taatcgacga gttttttgag attacacggt
     1921 ataacctaca aacgataacg ctaacaaaaa cgcacataga cctatactat atgctggtgc
     1981 agatgaccga tgaattttat cctcagcttt ccgcacatgg aaaacaggcg gttattcacg
     2041 cccccgagga tctgaccgtg tccggcgacc ctgataaact cgcgagagtc tttaacaaca
     2101 ttttgaaaaa cgccgctgca tacagtgagg ataacagcat cattgacatt accgcgggcc
     2161 tctccgggga tgtggtgtca atcgaattca agaacactgg aagcatccca aaagataagc
     2221 tagctgccat atttgaaaag ttctataggc tggacaatgc tcgttcttcc gatacgggtg
     2281 gcgcgggact tggattggcg attgcaaaag aaattattgt tcagcatgga gggcagattt
     2341 acgcggaaag caatgataac tatacgacgt ttagggtaga gcttccagcg atgccagact
     2401 tggttgataa aaggaggtcc taagagatgt atata
//
LOCUS       DBGZHO010000129         2395 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.140, whole genome shotgun sequence.
ACCESSION   DBGZHO010000129 DBGZHO010000000
VERSION     DBGZHO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.140"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            316..570
                     /locus_tag="ACN3HL_002819"
     CDS             316..570
                     /locus_tag="ACN3HL_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HHC8007603.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="ACN3HL_002820"
     CDS             571..888
                     /locus_tag="ACN3HL_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HHC8007604.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="ACN3HL_002821"
     CDS             1447..2382
                     /locus_tag="ACN3HL_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007605.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          338 c          453 g          743 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgatg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DBGZHO010000130         2176 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.141, whole genome shotgun sequence.
ACCESSION   DBGZHO010000130 DBGZHO010000000
VERSION     DBGZHO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.141"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..679
                     /locus_tag="ACN3HL_002822"
     CDS             <1..679
                     /locus_tag="ACN3HL_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007606.1"
                     /translation="VVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQF
                     IRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYL
                     FEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTS
                     IHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPY
                     VLGKVVI"
     gene            723..992
                     /locus_tag="ACN3HL_002823"
     CDS             723..992
                     /locus_tag="ACN3HL_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007607.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1224..1520
                     /locus_tag="ACN3HL_002824"
     CDS             1224..1520
                     /locus_tag="ACN3HL_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007608.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1522..1944
                     /locus_tag="ACN3HL_002825"
     CDS             1522..1944
                     /locus_tag="ACN3HL_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007609.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1963..>2176
                     /locus_tag="ACN3HL_002826"
     CDS             1963..>2176
                     /locus_tag="ACN3HL_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007610.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKT"
BASE COUNT          820 a          296 c          422 g          638 t
ORIGIN      
        1 ggtggtctat ggggtggcct attacttgtt aagtgagcca aaacagatcg cggcgtcaaa
       61 tattttcacg gcagtaatga cattaatgtg tgtcatgtgc ttttctattt ttagttactt
      121 actcgtccaa tttatcaggc aaaatttaac aatgagtaaa cttttcaaaa gtttattgga
      181 cttacttatc ttaggcagta tgttaacgac tctaacagat cggttcgaac aatctgaaaa
      241 aacggtagag gggataaaga acttcttaac gacgattgat caatttataa atggatatat
      301 gtatttgttt gaagtaggct ttattctcac tttgtttggt tgtgtattta taaaactcat
      361 taaaagatca atcgaaaaag aaatggttat tgatctaatt ccgacgctga gcggctatga
      421 gtattacgtt gattttggaa agtatgagga gttgatccat acggatatcg ttcacacgag
      481 tatccatgaa gtaaccgtta agggcatcag atctacttta aaagatggac aggagacgaa
      541 aacaatcgac cgaagaaaag aggtctacaa tttttataaa gttgaagcaa gtctacgata
      601 tggcattggg aaattgaggt tagatgggag taatattcaa caaaacaaac catatgtttt
      661 aggaaaagtg gtgatttaga acttcctatg aaagatgaat aaataaggag aatcttttga
      721 aaatgattct tctttacaga attgtgctta tagttggcac ggagttaaaa atcttaaaga
      781 aggagcagtt attcaaagtg aaagaacatc ataatcagtt actatgtatt aaaacgggta
      841 cgatgaacat tcaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
      901 cgattcgaga gcaacataag caagaaaaat taatggctac ttatagccaa ttgattgatg
      961 agtgggaaca attcaaggaa tctaaaacat aaaattccat ttaaacacct tattttttaa
     1021 agagcataag gaaacgtgac cccactttta aaaaaagtgg ttggataggc tgtgcctatc
     1081 acgtttctga aaaaaataaa tgaccccaaa ataccaatat ataggatagt acaaggatag
     1141 caaaggatag taaaaggata gaggtaggat agcgaaaagg ataggatcct tttcactatc
     1201 ctatattata ttggaggata tttatgaatg ttaaaattag agatttagat ccaaaattca
     1261 tttctgaaat tgatcgaaga tgcgttgaac taagtaatcg tacaggaaat aaatggagtc
     1321 gtaatgatta tttaaagcta ctcgttgaaa atgattttga tcgtcctttg atggaataca
     1381 aacaagaaaa gtttgaccag ttattagaaa agttttcaga aattcaaagt tataacacaa
     1441 agatattaga agaatatgtt agccaaaata atcgtattat agaaatcttg attgagcaaa
     1501 atagaggaag tgaactttga tatggcaaag gttatagaca aacacattta ctttcaccaa
     1561 acacatatcg atgtattgga tgaaactatt tctactcatg cagaggttaa aaactatagt
     1621 gaagctgttc gctttttatg tatgaactat gatccagaag tggagaaaaa agtaaattcc
     1681 aatcaagcaa agttgaatgg aatgagtaaa gaaatttcta ttttaaccga aatggtttca
     1741 gaatttgcgg atcttcattt gaaagataca ggaatattaa ttggtaaaaa ttcaactgtt
     1801 tatcaagaag caaaagaacg agtggaagga aaaattaaat ccaatcaaac aaaaaaatat
     1861 tcccctcagt tgaagaaacc tgtgaatgaa tctgttcatg ccagagtaga tccatttgat
     1921 ccaacgaaga ttctaaaaag ataaaaatga aggaggataa taatgactca atcgccttca
     1981 gttattctca cttgtcaatt tactttgccg aataaaaagt cattttctac ttatattgac
     2041 tatattacaa gggaacaggc tcttgaagaa aaggaacgac gtacgcccga agaagaacag
     2101 gaacttcaac gaatcaagaa tgctttagag gagttttata ttcctgaagg agaaactttt
     2161 tcggagagta agacgg
//
LOCUS       DBGZHO010000131         2162 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.142, whole genome shotgun sequence.
ACCESSION   DBGZHO010000131 DBGZHO010000000
VERSION     DBGZHO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.142"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            779..1111
                     /gene="traE"
                     /locus_tag="ACN3HL_002827"
     CDS             779..1111
                     /gene="traE"
                     /locus_tag="ACN3HL_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HHC8007611.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1730..2071
                     /locus_tag="ACN3HL_002828"
     CDS             1730..2071
                     /locus_tag="ACN3HL_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HHC8007612.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDNEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          767 a          282 c          438 g          675 t
ORIGIN      
        1 attaaaaatt ttttattatt ctaattatat tacgaatatt acaaaataat agctatttta
       61 atagaattta taagttaaaa tattatgata aaaatcacaa acgtagcctt ttacgtcata
      121 agtgttaaaa gaaataatta atttcaaata tagaaaaggg aacgtatgtt tgcatactcc
      181 ttttttttga gttataataa tacgcgaaga gagataattt cattatttaa acaagctaaa
      241 aatcttgata ttacttcttt tcaggcaata cgaatattat tcgcttacat tttttgtata
      301 aatttaattg tctgctatgc ttgtgatgaa ttgattttcg ttttgcactt ttggatgata
      361 aatttggaca attgaaaata caaaaaaaag aaaggcggta tgaactcgga aggctggtaa
      421 ccttcgtcag cgttcataca cggcattaag atttggccct taatgcgtta acctttcagt
      481 gttacggtat tacccgcaat ggatttagta taacagatat tcaaaagtga taccactttt
      541 tttggctgtg ttaaggttaa aaatacgtga tattacgatg aatctatgcc taagcataat
      601 gttataaaaa tgtccgtgtg gctctttgcc gtatgacgaa cgctgaaatt agagggaacg
      661 catgtttgga tgcgttccct cttttttgtt tgtcatgaac gaaaatcaat tctctatttt
      721 tgaaaaataa caagaaaaac ttgttaaaaa tatttaaaga aattgggtgg tttattttat
      781 gtcatataca ggaattttga gtctcaaaga tatttgtcac tacggtaaac ggtgtaccgc
      841 tacagagaaa atcacgaaga aactatcaac tggccaaagt aaaaccgttg tgcagtgtaa
      901 gaaatatata atccagaaag acaaagtctc agaggaaatg atttattaca ttgggaaaca
      961 aaagcaaata attttaaaag atcctatccc cttaaaagag ctatatccaa caatcaaaca
     1021 tgtttatgac caaaacggtg tactgattgg tcgaagaaaa aatggagtct tgcgttgtac
     1081 cgcaaaaggg atggggcgtt tgatcggctg aattgatcat tctcataact tgtattttat
     1141 cgtttttcgc ttgcttgaaa atattgtcga gacttctaaa ggaacttaga gtcactagaa
     1201 aaataaggag tagacttgat ctatcaacaa ttcccttcgg ggagtgacgg ggtaggtttt
     1261 aacgattggt aacgtaaaaa attggtcaat cgagtaaatg cgcttgtttg gatagtggtg
     1321 aaatgaattt gtgtaaataa taagcgcaga gtaaacaaga gggaatttag aagttagaca
     1381 agttagaata gcgtctagat taatcatgag cagctactaa gggatctaga ctttgacgca
     1441 aactcatgga ataaggagta ggtcttctcg taatggggag gacgcacaag aaattgtgtc
     1501 gtgtgctgca gtacatgtag atacttgcga ggacgttgat tattggatca atcgagcatt
     1561 taccgctgtc tactagggtt tctcgtttcg gacgccataa acgagtcgaa attttttatg
     1621 tatttttaag taaacgaaaa acgataaaat atgaacaagt cctgaataaa gtgaaaaaat
     1681 taatataaag catagagaaa atgaaattta cgtaatggag gaatgacaaa tgaaaaatta
     1741 tgatccgaat atacgattgg gcacacatac tattaaggtt tctttccaac gttgggatta
     1801 caaaggattt gtgacgttta gaaggggcgg aaattgtaaa ggattagatg ttttagcatt
     1861 agacgaggat gatttatacg atcaaacatt gactgataat ccaattggat tcggcttgct
     1921 acctgaagat aatgaaggta atgaatggtt taaaatgacg cttatgaatg ataatggaga
     1981 cgaattatct gttgaagata cttggtcata tttgagtgat tatattgtca gctttgaaat
     2041 cattgaattt gtagcggata aagaagaata aaaactggag gaataaattt tacagataaa
     2101 ggcttagaag gagtcacgac gattaataaa aaggtagtat taccttaggc attgagtaag
     2161 ga
//
LOCUS       DBGZHO010000132         2070 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.143, whole genome shotgun sequence.
ACCESSION   DBGZHO010000132 DBGZHO010000000
VERSION     DBGZHO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.143"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            336..716
                     /locus_tag="ACN3HL_002829"
                     /pseudo
     CDS             336..716
                     /locus_tag="ACN3HL_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            716..1513
                     /locus_tag="ACN3HL_002830"
                     /pseudo
     CDS             716..1513
                     /locus_tag="ACN3HL_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            1590..2070
                     /locus_tag="ACN3HL_002831"
                     /pseudo
     CDS             1590..2070
                     /locus_tag="ACN3HL_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          797 a          339 c          381 g          553 t
ORIGIN      
        1 ttcaatttgg cgttgctcat tttgatcaat cgacgaaact cgaatataag caattttcaa
       61 aatttttacc tacttcctca aactatttaa aatacactca aaatcaacac taattttttt
      121 atacactata aagctgtcat ttttctagat aaatggcata aattttcagc gctaagtgac
      181 aaaagcaact aatttttcat gatagatttt taaatatctc aatctatctc caaaattagt
      241 tgcttttgta gctatagttg actatgaata tgacaaataa ttagaaaaaa ctgtgccaat
      301 taaatatcaa aatgacaaat tgatgaatca aattcaaatt aaggggggca accctggaag
      361 tcttaaattt accctcaatg aatggtattg aagatgaaaa tttaaggcgt ttgattaata
      421 gccttgtcat tgaattgtac aagtatcaag cagaatcaga acgaaaaaaa attaaggaac
      481 gtcaggcaca aggaatcgaa attgctaaga aaaaaggcaa attcaaaggt cggcaactga
      541 aatttaaaaa aaatgatcca cgtttaaagc atgctttcga tttgtttttg aatggtttat
      601 ccgataaaga agttgaagaa caaactggga tcaatcgccg aacgtttaga aggtatcgag
      661 caagatataa cgtgacagta gatcaaagaa aaaacaatga aaagagggat agttaatgag
      721 tacggttatt ttagctgaaa aacaagccag gcattagcct acgcaagtgc tttaaaacaa
      781 agcaccaaaa aagacggtta ttttgagatc aaagacccac tatttacaga tgaaacgttt
      841 atcacctttg attttgggca tttagtggaa ttagcagaac caggtcatta tgacgaaaag
      901 tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga ttttgaagtt
      961 gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa ggcaaataca
     1021 attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc gattatccat
     1081 aaagcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa tagcttagaa
     1141 aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta ctatcccttt
     1201 tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa cgcaagccct
     1261 ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact aggacgtgtt
     1321 caaacgccca ccttatacct tatttttcag cgccaggaag ctagtataaa agtaaaacaa
     1381 gggtcattta agggcgttct aagccccaca cagcgtttta aaacccaaga ggagcttttt
     1441 tgcttttgtt tcttctaaac aagctaaaat aggcaatcaa gaggggataa ttgctgatgt
     1501 tcaaaccaaa gagatggata ggctacaatt aactagacag aaaaattaag gtgtgtagac
     1561 tagaagaaaa tataccagga ggaattttta tgtctaagag aacacgaaga actttttcac
     1621 aagaattcaa gcaacaaatc gtcaatcttt acttagctgg aaagccacgt gtagaaatca
     1681 ttcgagaata tgaactaacg gcttcagcat ttgacaaatg ggtaaagcaa tctaaaacga
     1741 gtggttcatt caaagaaaaa gataatctta cgcctgaaca aaaagaattg ttagaactac
     1801 gtaaaagaaa ccagcaatta gaaatggaaa atgatatttt aaagcaagca gcgctgatat
     1861 tcggacgaag agacaagtaa tcgatgcgaa taagcatctt taccctatat cagcgatgtg
     1921 cagaatatta ggtctatcac gtcagtccta ttattatcaa tcaaaaccaa agaaagacga
     1981 atcagaactt gaagaagtag tcgctgaaga atttatccgc agccgaaagg cctacggctc
     2041 aagaaaaata aaaaaagcct tatcaaaatg
//
LOCUS       DBGZHO010000133         2056 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.144, whole genome shotgun sequence.
ACCESSION   DBGZHO010000133 DBGZHO010000000
VERSION     DBGZHO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.144"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            493..714
                     /locus_tag="ACN3HL_002832"
     CDS             493..714
                     /locus_tag="ACN3HL_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007613.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="ACN3HL_002833"
     CDS             715..972
                     /locus_tag="ACN3HL_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007614.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="ACN3HL_002834"
     CDS             complement(1108..1710)
                     /locus_tag="ACN3HL_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HHC8007615.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="ACN3HL_002835"
     CDS             complement(1777..1932)
                     /locus_tag="ACN3HL_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HHC8007616.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DBGZHO010000134         2001 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.145, whole genome shotgun sequence.
ACCESSION   DBGZHO010000134 DBGZHO010000000
VERSION     DBGZHO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.145"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..376
                     /locus_tag="ACN3HL_002836"
     CDS             <1..376
                     /locus_tag="ACN3HL_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HHC8007617.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            424..1824
                     /locus_tag="ACN3HL_002837"
     CDS             424..1824
                     /locus_tag="ACN3HL_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HHC8007618.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
BASE COUNT          553 a          339 c          432 g          677 t
ORIGIN      
        1 aaatgtttcc acagaggact tctttaatta ttgtcgatta gaggaaagtg gtgtaacagt
       61 cactagcggt acagatttac cgctgtttat tactgatatt cctgaatcga ttataagagc
      121 agtattccgt cgttttcctg aaggagaaga agtctgggag aaagaaacaa gcttcacgac
      181 aaccgagctg ctgaaaagtt ttacaagcaa cagcttcaaa gtaaatggtt tatcggagta
      241 cggagaaata aaagtaggga aaagcgccag cttagctgtt ttcagcgagg acctctgtac
      301 tgatgactgg caaaaagtga tggctgcgga agttatcgct acctatcttg atggtgactt
      361 agtttacaag aaataatgct tttcgatata acgttataaa acgaattaaa gagaggttaa
      421 aaaatggaaa caatgaaaag aaaattcacc ttcccacata gttatacatt gatttttatc
      481 ttaattattt tggctgcaat tttaacttgg ataattccta gtggtcagtt tgagacagtt
      541 gttgaaaacg tcgcaggtat ggaaaaaaca acggttgttc cgggaaccta tcaccaaatc
      601 gataaggcag attatggaca aggtttttcc tctatactaa tggcaccagc tgaagggatt
      661 atttcagctg ttgaggttgt tgcttttgtt ctcatcgttg gtggtgcctt cgggattatc
      721 ctaaaaacgg gagccatcga tcgagggctg tttaccttag caaaagttct gggagacaag
      781 gggatcttag ttattccgat gtcgatgatt ctattcagct taggaggatc aacctttggc
      841 atgagcgagg aagtcattcc cttatttgcg gtgtttattt ctctgatgtt ttctcttggc
      901 tatgattcca tgactgcgat cttgattcta tttttaagta cacaagcggg atatgttggg
      961 tcgacgatta atcccttcaa cgttttaatc gcacagggag tagctggcgt ttacggaaat
     1021 cccctgcttt ggtttcggat gctatcctgg attgtcatta ctgggatttc aattgttttc
     1081 accatgcttt atgctagcag agtcaaaaag aatccactgt cctctattgt ttatgagagt
     1141 gatttaaagg ttaagcataa gtttcaaaat tttgacactg aaaaagagtt ttcaacacaa
     1201 gataaactaa ttatcgccgg ttttatcgta ggtttaggaa tcatgatttg gggtatcatt
     1261 tccaagggat ggtatatggt tgaaatttct gcactattct taggattagg tctttttgct
     1321 gggggcatcg ctagattttc tcaaaaggaa attgctgaag cttttgtcga aggctgttca
     1381 gatttcgcct atgctgctgt aatcattggg ctagctagag gagtcttggt aatcttggaa
     1441 ggtggaatga ttattgacac tattctaaac agcttggcta accttttagg tggtcttcca
     1501 aaattcctgt tcactacgat tctactcatt tctcaagtaa ttgtttcctt ttttgttcca
     1561 tcctcctcag gagctgcggc attaacgatg ccggttatgg caccattggg tgatctaatg
     1621 aatgtaagtc gtgatgttgt tgttctaagt aaccagtttg gaaatggttt aatgaatatt
     1681 atctccccaa ctagtggtgt attactggca ggattagcca tcgcagagat taatttctct
     1741 aaatggttta aggttggctt caaaatattt gccatcttaa cccttgtttc tgctgttttg
     1801 ttatacattg ctacactctt ttagtcttaa tcatccatta ataggaggca atagttatga
     1861 ttaaaataaa tcaattagca ggaatgaata tccactattt attttattct ctcaaagaat
     1921 ttttcgctta tcaacagaaa attggtattt cttctgttga actttgggga ggtgctccgc
     1981 attttttcat agatgctttt a
//
LOCUS       DBGZHO010000135         1991 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.146, whole genome shotgun sequence.
ACCESSION   DBGZHO010000135 DBGZHO010000000
VERSION     DBGZHO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.146"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="ACN3HL_002838"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="ACN3HL_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HHC8007619.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="ACN3HL_002839"
     CDS             852..1040
                     /locus_tag="ACN3HL_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HHC8007620.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="ACN3HL_002840"
     CDS             1053..1610
                     /locus_tag="ACN3HL_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HHC8007621.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="ACN3HL_002841"
     CDS             1642..1884
                     /locus_tag="ACN3HL_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HHC8007622.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          724 a          308 c          406 g          553 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaac
     1921 aaatttgaga accgtagcga cactcgctgc ggttcttttt tatatatttt atatgaagta
     1981 ttctttattc c
//
LOCUS       DBGZHO010000136         1933 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.147, whole genome shotgun sequence.
ACCESSION   DBGZHO010000136 DBGZHO010000000
VERSION     DBGZHO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.147"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            675..1901
                     /locus_tag="ACN3HL_002842"
     CDS             675..1901
                     /locus_tag="ACN3HL_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8007623.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
BASE COUNT          721 a          291 c          303 g          618 t
ORIGIN      
        1 tattttaaat ttttacatac ctgtttatga aaaactaaat aatctgtcaa aaaaatatga
       61 ttgttcattt ctaaatatgt tttccaattt taaaatcttt tttagcattt ttgtttcctt
      121 ttcatatggt ttttcgttgt taatagtgac taggatgata ttcctatttt gaccattgac
      181 aattaaatat aatttttgaa taacgttccc tgctattcga gctaagaatt caagtacgcc
      241 atgacctatt tagcgataac tacttagaga tttctttttg ttttgggaag acaaaatgcc
      301 atgacaatag cagtagataa tgatacttcc gtaaggctcg ccgtaaactg gggagaggtg
      361 aaattcctat gtgcttaccc aagtcaattc aaaaatttta gttcatttat aaggggatga
      421 ttttattaaa tcaatagtct atctaaacaa aaaacaaacc tgtgagtttt taggaattga
      481 taacaatact ttagataaat ggattcgtat atataatttt cccgtaataa aaatagacgg
      541 tataattcgc tttgatgtag aagatatcaa aggctttatg gatacgttca aaaagatttg
      601 aattttactt ttgactgcat atactaaaag tagcgaaata tactgcctta cttttttatt
      661 aaggagtgag gaagttgcct acgaagcttt caaatggaaa atataaaact aatttgagat
      721 atccaaaaaa atttaaagaa attacaggta tcagttcaga aaaattccaa aaaacatttc
      781 caactaggca attggctatt aaagccgaaa atgaaatgaa aaagaaaatc gcaaaagtct
      841 taagagagga gaatgcaaat tcattagagc tcaaaggtca aataaaattc aaggagtttt
      901 ataaatctaa atggcttcct agatatgagt tagggcaaac tactagatcc cataaagctc
      961 caagcgatat aaccatcatt aatacaaaga atttatttcg attgcatatt ctgcctatat
     1021 ttggtgagta tgccatgagc tatcttaatg caaataccga aataatatca gatgaactca
     1081 caaaaaagtc gaaggaatat gcaaacataa aaatcattaa atgctatgtt cgttccatgt
     1141 ttgatattgc agaggttcta aattatattg aatttaatcg tacaacaaaa ataattcaaa
     1201 gtattactgc acctaagaaa gttgctctgg aagaaaaaag aatacgagaa ggaaaacaag
     1261 ctttatcttc gaaagaactc actgattggt tagacgctgt aagagatgat ttcaatgatc
     1321 aattactttc ctttcacgat tacactcttt ttatgcttac tttatatctt ggggatagaa
     1381 agagtgagac ctatgctttg caatggaaat acattgattt tgaaaaccaa acagtccgtc
     1441 ttaaatatgc cttggataaa cacacaaaaa agaaatttac aaaaggtcga aaagatacta
     1501 ttatccaagt tccggaaatt gtaatgacac tattgcaaga atggaaatca gtgcaagctg
     1561 aacaactatt gaagttgaaa attaaacaga cacctgacca atatcttttt agttactcca
     1621 aaccttctgg tgaagtaaat tgtccagtcc atactgatta cttaaattat cgaattaatt
     1681 ctataaaaaa aagacatccc catttggttc atttaactcc tcataaactt cgacatactt
     1741 acgcaacttt agctagacaa ggtggggctg atatgaatca aatttctaac gctttgacac
     1801 attcaggtat ttcaactaca aaaatttatg tgaatacacc tgatttagtt gataaagctg
     1861 tgttcgaagc gtttcagcga ggattacaaa aatctaatta atgtgttcta gaatgtgttc
     1921 taaatataaa aaa
//
LOCUS       DBGZHO010000137         1573 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.148, whole genome shotgun sequence.
ACCESSION   DBGZHO010000137 DBGZHO010000000
VERSION     DBGZHO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.148"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            46..105
                     /gene="ermCL"
                     /locus_tag="ACN3HL_002843"
     CDS             46..105
                     /gene="ermCL"
                     /locus_tag="ACN3HL_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HHC8007624.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            165..899
                     /locus_tag="ACN3HL_002844"
     CDS             165..899
                     /locus_tag="ACN3HL_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HHC8007625.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          588 a          249 c          211 g          525 t
ORIGIN      
        1 cttgtgctat aattattcta atttcataaa aaggagaatt aatatatggg catttttagt
       61 atttttgtaa tcaacacagt tcattatcaa ccaaacaaaa aataagtggt tataatggat
      121 tgttaatata aacattcatt ataacctcat aggagtgggt tataatgaac aaaaaaaata
      181 taaaagatag tcaaaacttt attacttcaa agcatcatat aaatgaaatt ttgagaaatg
      241 tacatttaaa tacaaatgat aatattattg agattggttc agggaaaggt catttcacgt
      301 ttgaattagc taaaaggtgt aattatgtaa ccgccattga aatagatcct aaattatgta
      361 ggataactaa aaacaaactt attgaatatg agaacttcca ggttatcaat aaagatattt
      421 tacaatttaa gtttcctaaa aataagtcat ataagatata tggaaatata ccctacaata
      481 taagtacaga tataattcga aaaattgttt ttgaaagcac agctacagaa agttatttaa
      541 tagtggaata tggatttgct aaaaggttgc taaatacaaa tcgttcacta gcactatttt
      601 taatgacaga agttgatata tccatattaa gtaaaatccc tagagaatac tttcatccaa
      661 aacctagagt taatagctcg ttaattgtat taaaaagaca cccttcaaaa atatcactca
      721 aagatagaaa acaatatgaa aattttgtta tgaaatgggt taacaaagaa tacataaaac
      781 tattttccaa aaaccaattt tatcaagcct taaaatatgc aagaattgac gatttaaaca
      841 atattagctt tgaacaattc ttgtctcttt tcaatagcta taaattattt aatagataag
      901 ttaaggggtg cataaactgc atcccttaac ttatcttatt ttgcttaaac aatcttggcc
      961 cgtaaactgc ataactcata tgtaaatcgc tcctttttag gtggcacaaa tgtgaggcat
     1021 tttcactatt tccggcaatt acttccatgt aaagtataac ccactatact ttgcaagcaa
     1081 agtgtgggct cgccgagggg tcttgcagac ggctctttcg gctcttttga gccgagtatc
     1141 agcgcaccct tatggtgcaa ttagctgata cctgtttgac gatttgctgc cctacctttt
     1201 cggtaggtat gcaaacctca aaccaaaata aaaaccccct tcgacttcgt cagggggttt
     1261 ttatttatat aaatctccgt aaataatcgc gatttaataa catcttcaat tttatttttt
     1321 tgcgtatttt agaaatgttt tcactaaaaa atatattata caaaaaatac agtaatcgat
     1381 tataattctt tgccagttaa atatcatatc gttattaaaa tatcggaaaa aaatatcaac
     1441 aacaataaat gcaaaagaag accataaaaa ttgtttatta ctcatacata ctctccattt
     1501 ctatcatttt taaatttacc agtcatctct caaaaatctc ctagctattt ttctttttta
     1561 accacatacc gtc
//
LOCUS       DBGZHO010000138         1466 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.150, whole genome shotgun sequence.
ACCESSION   DBGZHO010000138 DBGZHO010000000
VERSION     DBGZHO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.150"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..300)
                     /locus_tag="ACN3HL_002845"
     CDS             complement(<1..300)
                     /locus_tag="ACN3HL_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HHC8007626.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACN3HL_002846"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACN3HL_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACN3HL_002847"
     CDS             complement(1014..1304)
                     /locus_tag="ACN3HL_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007627.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          469 a          288 c          205 g          504 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tataga
//
LOCUS       DBGZHO010000139         1461 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.151, whole genome shotgun sequence.
ACCESSION   DBGZHO010000139 DBGZHO010000000
VERSION     DBGZHO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.151"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1359
                     /locus_tag="ACN3HL_002848"
     CDS             <1..1359
                     /locus_tag="ACN3HL_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HHC8007628.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
BASE COUNT          481 a          266 c          308 g          406 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgtac aggtactgtt ctatggggcg cttacttttc
     1441 ttcttcaaga ccaaataaaa a
//
LOCUS       DBGZHO010000140         1458 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.152, whole genome shotgun sequence.
ACCESSION   DBGZHO010000140 DBGZHO010000000
VERSION     DBGZHO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.152"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..362
                     /locus_tag="ACN3HL_002849"
     CDS             <1..362
                     /locus_tag="ACN3HL_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HHC8007629.1"
                     /translation="LSKEHGQVKEKYSGLVERFNENVNDYNELLEENKSLKSKISDLK
                     RDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEFELT
                     HNREVKKERSRDQGMSL"
     gene            607..>1458
                     /locus_tag="ACN3HL_002850"
     CDS             607..>1458
                     /locus_tag="ACN3HL_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HHC8007630.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT          573 a          170 c          294 g          421 t
ORIGIN      
        1 aattaagtaa agaacatggg caagttaaag aaaaatatag tggtcttgta gagcgattta
       61 atgaaaatgt aaatgattat aatgagttgc ttgaagaaaa caagtcttta aagtctaaaa
      121 taagcgattt aaagcgtgat gtgagtttaa tctatgaaag cactaaggaa ttccttaagg
      181 aacgtacaga cggcttaaaa gcctttaaaa acgtttttaa ggggtttgta gacaaggtaa
      241 aggataaaac agcacaattc caagaaaaac acgatttaga acctaaaaag aacgaatttg
      301 aactaactca taaccgagag gtaaaaaaag aacgaagtcg agatcaggga atgagtttat
      361 aaaataaaaa aagcacctga aaaggtgtct ttttttgatg gttttgaact tgttctttct
      421 tatcttgata tatatagaaa taacgtcatt tttattttag ttgctgaaag gtgcgttgaa
      481 gtgttggtat gtatgtgttt taaagtattg aaaaccctta aaattggttg cacagaaaaa
      541 ccccatctgt taaagttata agtgaccaaa caaataacta aatagatggg ggtttctttt
      601 aatattatgt gtcctaatag tagcatttat tcagatgaaa aatcaagggt tttagtggac
      661 aagacaaaaa gtggaaaagt gagaccatgg agagaaaaga aaatcgctaa tgttgattac
      721 tttgaacttc tgcatattct tgaatttaaa aaggctgaaa gagtaaaaga ttgtgctgaa
      781 atattagagt ataaacaaaa tcgtgaaaca ggcgaaagaa agttgtatcg agtgtggttt
      841 tgtaaatcca ggctttgtcc aatgtgcaac tggaggagag caatgaaaca tggcattcag
      901 tcacaaaagg ttgttgctga agttattaaa caaaagccaa cagttcgttg gttgtttctc
      961 acattaacag ttaaaaatgt ttatgatggc gaagaattaa ataagagttt gtcagatatg
     1021 gctcaaagat ttcgccgaat gatgcaatat aaaaaaatta ataaaaatct tgttggtttt
     1081 atgcgtgcaa cggaagtgac aataaataat aaagataatt cttataatca gcacatgcat
     1141 gtattggtat gtgtggaacc aacttatttt aagaatacag aaaactacgt gaatcaaaaa
     1201 caatggattc aattttggaa aaaggcaatg aaattagact atgatccaaa tgtaaaagtt
     1261 caaatgattc gaccgaaaaa taaatataaa tcggatatac aatcggcaat tgacgaaact
     1321 gcaaaatatc ctgtaaagga tacggatttt atgaccgatg atgaagaaaa gaatttgaaa
     1381 cgtttgtctg atttggagga aggtttacac cgtaaaaggt taatctccta tggtggtttg
     1441 ttaaaagaaa tacataaa
//
LOCUS       DBGZHO010000141         1456 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.153, whole genome shotgun sequence.
ACCESSION   DBGZHO010000141 DBGZHO010000000
VERSION     DBGZHO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.153"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(100..1119)
                     /locus_tag="ACN3HL_002851"
     CDS             complement(100..1119)
                     /locus_tag="ACN3HL_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HHC8007631.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1130..1336)
                     /locus_tag="ACN3HL_002852"
     CDS             complement(1130..1336)
                     /locus_tag="ACN3HL_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HHC8007632.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          403 a          303 c          246 g          504 t
ORIGIN      
        1 tgggtgatag tgaagatatg cgataacatc actattttat cgaatgattt ttatagttgt
       61 caatatagtt atgtaatgct cctcaacgag gagctatttt tatcgtttag gaatatttaa
      121 ataccaacgt ttgtcatgga aatcttgcgc accgccttta gtgtttccct ctggatcatt
      181 cgttgcccgc atcatgacat agactttctt attagggaag ttacgcatgt taaaagatac
      241 atgatagcca acatttccag aagtattata agcttgattt acatctgatc tataaattcc
      301 atcagctctt actcgagcta attctttccc agtattgtaa tccataatga agatatactc
      361 gtatttatag ttagcaatgt gccatccagc tacatgcaaa tttgcatttt cgatttctcc
      421 aaactgatca atgtgggcgt aattcgttcc atctgtcagt gtaggattag ctgcaccagc
      481 tcgtgttgga tcaatgacag gcttgttttc agaagttgtt ggattttcat cggtaaatcc
      541 atgagctaaa tcatatgcta atttttcttt acttacgccc atttcagaaa gataaccgta
      601 aggatctgta tgatcgcccc agatgttttg tgttacccat aaatgcgatt tgattcccgg
      661 ttggttataa ggagtgtcca acgttaatgg aataccatat ttcattgctg aatctctagc
      721 caattcaacg tatgccttgt agtttttctc aaacgttgct ttatcatgtg tgtgttgtaa
      781 ctcaatctgc acaggactgt tggcattagc atacgaacca gcaccgtact gtacataacc
      841 aggttgaccg acttgataaa caattccgcc gtctcccaca atataagcag tataagcgct
      901 agtccatgaa cgttgcatat actgcgcttc attgcgtcct gttgctgttt cattagccgt
      961 ttcatgcagt aaaatatact gattatttgc tacttgtgag ctaccttcat ttgcgcccaa
     1021 attaaattca ttgttgatag tataggcaaa tccgttaatt ggcaataaaa aaagagccgt
     1081 taacaggctc atcgcagtaa tagtaatttt ctttttcata tctatcctcc tatttatctg
     1141 atgaaatttt cttatacgtt cgatttgata cacctaaaat actccctaga aatgctccaa
     1201 aacctgtaat aatcatcacc gttatatctg tgtaccgcca gttaacacct tttccgacaa
     1261 gaccgacaaa agtcgctaaa gcggggataa ctactatagc gatccatttc aaaatatcaa
     1321 aggttctatt gttcatacta tccacctccc ttcattggtt gggctacttt ctttttcaat
     1381 cgcttgtttt cttctatcaa tatttctctt tctgaaagca aggcatcaat ttgcccgtcc
     1441 agttgttcaa ttttat
//
LOCUS       DBGZHO010000142         1455 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.154, whole genome shotgun sequence.
ACCESSION   DBGZHO010000142 DBGZHO010000000
VERSION     DBGZHO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.154"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1040
                     /locus_tag="ACN3HL_002853"
     CDS             <1..1040
                     /locus_tag="ACN3HL_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HHC8007633.1"
                     /translation="EINQKYDETLKNVYSSLIVSNIEETSSSEIKNKLSLLKLKEKEY
                     IIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTREKIIKIFDKI
                     NNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEKVRREID
                     REKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEVIRENVL
                     QRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHAMIF
                     SEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAE
                     QYRRSLELSKD"
     gene            1112..>1455
                     /locus_tag="ACN3HL_002854"
     CDS             1112..>1455
                     /locus_tag="ACN3HL_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007634.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          640 a          169 c          227 g          419 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caaga
//
LOCUS       DBGZHO010000143         1424 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.155, whole genome shotgun sequence.
ACCESSION   DBGZHO010000143 DBGZHO010000000
VERSION     DBGZHO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.155"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            4..1424
                     /locus_tag="ACN3HL_002855"
                     /pseudo
     CDS             4..1424
                     /locus_tag="ACN3HL_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          590 a          223 c          318 g          293 t
ORIGIN      
        1 gtcatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgagaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaatcc gaccatttat tttctgaaag
      541 gctatcgaaa agtcgcttta gaactgaatg aaaacgggga atttgaggaa tctaaaaaat
      601 accaagccac gtcggaagag gaaaaagcag ctgttcgtga attacttgaa gaggctgtac
      661 caactgattt tttgaaggag aaagaaaacg atcattttta tcgagtagaa ttcaacgaaa
      721 atgatccaga aaaaggattg aaaagttatg gtggggagat cgtaacattc gaattgatcg
      781 atcaactcaa aacgttggat aaccaatacg ccgcagaagc aggttattat aaattctatt
      841 ttgaagaagt gaagaacgga gaagtagtcg atcagatccg aatggatcta ggggatggcg
      901 tcaacagtaa tcaacccatc tatttagagt tagcaaaatt gtgcgaacaa gtacctgaga
      961 aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa agaacaaatg cagtcgaaag
     1021 aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc agaagagatt aaacaagaag
     1081 ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa gcatactcat tctcctgaag
     1141 acgtcaaaga acttttgaac tttatgtctc gttttccaga acgatccttt agaaatcaat
     1201 tattgattga ggaacaattt ccaggtgcaa cggcttgttt aggtcgtgcc gcgttgaaaa
     1261 aagaaggaat ctatatcaaa aaaggggaac aagggaacaa gatctttgtc agaaaaacgg
     1321 tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga aatagaagct acaccagaag
     1381 ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa aaaa
//
LOCUS       DBGZHO010000144         1424 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.156, whole genome shotgun sequence.
ACCESSION   DBGZHO010000144 DBGZHO010000000
VERSION     DBGZHO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.156"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="ACN3HL_002856"
     CDS             complement(150..1337)
                     /locus_tag="ACN3HL_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HHC8007635.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DBGZHO010000145         1421 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.157, whole genome shotgun sequence.
ACCESSION   DBGZHO010000145 DBGZHO010000000
VERSION     DBGZHO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.157"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1407
                     /locus_tag="ACN3HL_002857"
     rRNA            <1..1407
                     /locus_tag="ACN3HL_002857"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          388 a          305 c          429 g          299 t
ORIGIN      
        1 ccaagcagta agtctgaaga ggagtcaaat gcttcttttc ttaaggacaa gctgtgatgg
       61 ggagggaaat aatagtaccg aagttcctga tgtcacactg ccgagaaaag cttctagtga
      121 gaaaacagcg gcccgtaccg caaaccgaca caggtagtcg aggagagaat cctaaggtga
      181 gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg gagaaggggt
      241 gctgatcata cgatcagccg cagtgaatag gcccaagcga ctgtttatca aaaacacagg
      301 tctctgcaaa atcgtaagat gaagtatagg ggctgacgcc tgcccggtgc tggaaggtta
      361 agaggagtgc ttagcgcaag cgaaggtacg aattgaagcc ccagtaaacg gcggccgtaa
      421 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
      481 cgtaacgatt tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga
      541 tgcaggttac ccgcgacagg acggaaagac cccatggagc tttactgtag tttgatattg
      601 agtgtctgta ccgcatgtac aggataggta ggagccgtag aaatcggaac gctagtttcg
      661 atggaggcgc tggtgggata ctacccctgc gttatggcca ctctaacccg caccactaat
      721 cgtggtggga gacagtgtca gatgggcagt ttgactgggg cggtcgcctc ctaaaaggta
      781 acggaggcgc ccaaaggttc cctcagaatg gttggaaatc attcgaagag tgtaaaggca
      841 gaagggagct tgactgcgag accaacaagt cgagcaggga cgaaagtcgg gcttagtgat
      901 ccggtggttc cgcatggaag ggccatcgct caacggataa aagctaccct ggggataaca
      961 ggcttatctc ccccaagagt ccacatcgac ggggaggttt ggcacctcga tgtcggctcg
     1021 tcgcatcctg gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac
     1081 gcgagctggg ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgttggaa
     1141 atttgagagg agctgtcctt agtacgagag gaccgggatg gacttaccgc tggtgtacca
     1201 gttgttctgc caagggcatt gctgggtagc tatgtaggga agggataaac gctgaaagca
     1261 tctaagtgtg aagcccacct caagatgaga tttcccattt ctttaagaaa gtaagatccc
     1321 tgagagatga tcaggtagat aggtcaggag tggaagtaca gtgatgtatg gagcggactg
     1381 atactaatcg atcgaggact taaccaatag gttaaaagaa a
//
LOCUS       DBGZHO010000146         1420 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.158, whole genome shotgun sequence.
ACCESSION   DBGZHO010000146 DBGZHO010000000
VERSION     DBGZHO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.158"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="ACN3HL_002858"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="ACN3HL_002858"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HHC8007636.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          495 a          184 c          236 g          505 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact attactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tggactaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaac ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg
     1141 tatattatgc tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac
     1201 ttaatccata gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca
     1261 ccccaaacca cttccccata agtgtattac gctttaaact cttttatatt tgaattcact
     1321 aagaagcata ccatattttt gaaaaaaagt gagaaaaaag gcttataatt aggatttaga
     1381 gtaattaatt agatgtttat tttataggac tgatactata
//
LOCUS       DBGZHO010000147         1334 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.159, whole genome shotgun sequence.
ACCESSION   DBGZHO010000147 DBGZHO010000000
VERSION     DBGZHO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.159"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            86..1165
                     /locus_tag="ACN3HL_002859"
     CDS             86..1165
                     /locus_tag="ACN3HL_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHC8007637.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          359 a          357 c          369 g          249 t
ORIGIN      
        1 agccatttgg aaataaaaaa acgccacgtg aattccatgt tatattgaag ttaccacaac
       61 tctcaataga caaggatgaa ttcacatgac gcaaaaccat gataacacag tttcacgcaa
      121 gggaaaacac ctaacctact cagaacgttg ccaaatcgcc atcctgaaaa aggaaaacta
      181 ttccaaccgt caggttgcgg atgtcctggg ctgcgtgccg cagaccataa acaacgaaat
      241 caaacgcggg accgttactc agcttaaccg ccagaatcag aacgggaagg tctacgacta
      301 ttatcatgac gtctacgacg ccgatgccgg gcaggcggcc tacgagaaga accgcttgaa
      361 ctgcggcaga cggcccttat gggccgacac ggacgccttc attgaatggg cggacgacat
      421 gatgctgttg gaaaaatggt ccccggacgt ggtggtgggc tttgccagaa aacacgaatt
      481 gttcgacccg gccattatcc ctgggaccac caccctctat cagtggatcg accgtggcat
      541 catgaaaacg aagaatatgg acctgctaga aaaactgtcc cgcaaaccga aatcgtcccg
      601 tcatggcaac cgcccgaata aacgggtgct agggaaatcc attgaagagc gcccggaggc
      661 ggttggtacc cggaaaacct tcggccattg ggaagtcgac acggtcgtag gaaacaagac
      721 caagtcggat gccgtgctgc tgacgttggt ggaacggcag acacgcttcg aggtcattct
      781 gaagctggcc gggaaggatg ccgaatcggt caaccaagcg gtccgacagc tgagagaacg
      841 ggctggtgcg tacttcggcc agctgttcaa gacggttacc tcggacaacg gctcggagtt
      901 cgcgggactg cacgatgcct tgcaggatgt ggcaaacatc tacttcagcc acccctatgc
      961 ttcctgggag cgcgggacga gcgaaaacca acacaagctg attcgccgtt tcatccccaa
     1021 gggcagccca atcggcaacg tgagcgaaaa ccaaatcttg cggattcagc gttggatgaa
     1081 cgattacccg cgaaagattt tgggctatgc aacgccgcat gacacgttcg tccaggcatt
     1141 taggcaggaa cggttgacgg cttgacacgt gggcccttga caacgagcct ccctcggcat
     1201 ggcttgtgtc tggaaagctg gccggggcca gccagtcggg agactaccat gcctcagctc
     1261 attgtcaagg gcccactcga ttagaaaaat tagacggttg gtggtaacga gcaaccgggt
     1321 caccatgggt ggct
//
LOCUS       DBGZHO010000148         1324 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.160, whole genome shotgun sequence.
ACCESSION   DBGZHO010000148 DBGZHO010000000
VERSION     DBGZHO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.160"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            37..>1324
                     /locus_tag="ACN3HL_002860"
     CDS             37..>1324
                     /locus_tag="ACN3HL_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HHC8007638.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYE"
BASE COUNT          425 a          268 c          247 g          384 t
ORIGIN      
        1 ttgaatcacc acaacacaat caaaggagcg ttctgtatgc ctgatcttca tcatatcaaa
       61 ctactacttg gaatcaaaga taaaaacatt ttcatcacaa atgtggaatc gaagagcatt
      121 aagaatatca agagtcttgt tgtttctgcg acgttaagta aagaaattcg tcgctgtcct
      181 ttgtgtaaac agatgaatca tgaaggcatg atcgttaaga acggaaagaa aaaatcgctc
      241 attcaactta ataaatgtgc gaaccaactg acttatcttg ctttagcgaa acaacgctac
      301 cactgtcgtg gctgccacac ctattttacg gcgaatacct acattgtcga tagaaactgc
      361 tttatcgcta aacaagtgcg ctataaaatt ttagaagagc taactgaaaa acaagcaatg
      421 acgacaattg ctaagcattg cggcgtttct tggtcgaccg tttctcggac actcgcttct
      481 ctgatcccca tgacaaaagt aaaaagaaat tggttaccgc gttgtttatt aatggatgaa
      541 tttcgttcac tgaaaaatca agtcggtccc tactcctttt cttgtatgga tggcgatact
      601 ggaaaattac tggatattct tccttcacgg aagaaaaagg ctctcgtttc ttattttatg
      661 caatttgaac gacgcgcacg attgaaggta aaggtcatcg tgacggacat gaatgtttct
      721 tatgcctctc tgataaagga atgttttcca aaggcaaaac tcgttgtgga tcgttttcac
      781 attgtcaaac atctcattcg taaatttgag gatattcgcg tacgaatcat gaaaagcttt
      841 gatcgaaacg atccaacaca agccaaatat tatcgacaat taaaggcgtt gtctcggctt
      901 ctgatcaaac gacaggacaa gcttgtttat gacaaatgga ccaaatggcg caattttggt
      961 tgggcgtatc tcaccgaaag tgaagtggtg gatcgtctgc tttcgatctc tgacgaatta
     1021 cgaatcgcct atttttacta tcaagaaatt cttcaagcgt ttcacgacaa agaggcggac
     1081 actttcttta aacttgtaag aacgatgccc aattccgttc caaaagaact gcattctata
     1141 aaaaaagctt ttataaacta tgaatccggc attcgtttag ccctcgaatt gccttattca
     1201 aatgccaaaa tagaaaatct gcatacccac atcaaagcat tgaaacgagt cgcttatggc
     1261 tttcgaagct ttcggaaaat gaagaccaga attttcttac taaataatct gattacctat
     1321 gaat
//
LOCUS       DBGZHO010000149         1313 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.161, whole genome shotgun sequence.
ACCESSION   DBGZHO010000149 DBGZHO010000000
VERSION     DBGZHO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.161"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..>1313)
                     /locus_tag="ACN3HL_002861"
     rRNA            complement(<1..>1313)
                     /locus_tag="ACN3HL_002861"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          275 a          391 c          260 g          387 t
ORIGIN      
        1 ctccattgct caaacaaaaa caacgggtac aggaatatca acctgttatc catcgcctac
       61 gcctgtcggc ctcggcttag gtcccgacta accctgggcg gacgagcctt ccccaggaaa
      121 ccttagtcat tcggtggaca ggattctcac ctgtctttcg ctactcatac cggcattctc
      181 acttctaagc gctccagcag tcctcacgat ctgccttcaa cgcccttaga acgctctcct
      241 accaatacac ctaaaggtgt actccacagc ttcggtaata tgtttagccc cggtacattt
      301 tcggcgcagg gtcactcgac tagtgagcta ttacgcactc tttaaatggt ggctgcttct
      361 aagccaacat cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg
      421 ggaccttagc tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt
      481 ctgactcccg gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat
      541 gggcccctag tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa
      601 agctatttcg gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca
      661 cctcatcccc gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc
      721 ttcaacctgg acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc
      781 ctattcagac tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt
      841 aactcgccgg ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt
      901 gtaggcacac ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc
      961 tcacggtact ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc
     1021 cggattccga cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca
     1081 catttcgtct acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct
     1141 gaaagaacta ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt
     1201 ttcccgtttc gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact
     1261 tagatgtttc agttctctgc gtctacctcg aatgtgctat gtattcacac aat
//
LOCUS       DBGZHO010000150         1312 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.162, whole genome shotgun sequence.
ACCESSION   DBGZHO010000150 DBGZHO010000000
VERSION     DBGZHO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.162"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(156..1297)
                     /locus_tag="ACN3HL_002862"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="ACN3HL_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HHC8007639.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          323 a          263 c          278 g          448 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc tt
//
LOCUS       DBGZHO010000151         1298 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.163, whole genome shotgun sequence.
ACCESSION   DBGZHO010000151 DBGZHO010000000
VERSION     DBGZHO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.163"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            143..400
                     /locus_tag="ACN3HL_002863"
     CDS             143..400
                     /locus_tag="ACN3HL_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007640.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="ACN3HL_002864"
     CDS             complement(632..1063)
                     /locus_tag="ACN3HL_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HHC8007641.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          490 a          166 c          162 g          480 t
ORIGIN      
        1 ttttctgtcc acgttcatat tactccaaag ttttcctcat tccaaaagaa aagcacagaa
       61 tacacaaaga agcgttttta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt gttactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacatc ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc taaaatataa
     1201 gctatttgtt tacttctgta gaatatatac tttgttgtta gataagttgc acatgtttat
     1261 agaatctaaa taataaattt ttatgtaccg cccctcaa
//
LOCUS       DBGZHO010000152         1292 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.164, whole genome shotgun sequence.
ACCESSION   DBGZHO010000152 DBGZHO010000000
VERSION     DBGZHO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.164"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            42..>1292
                     /locus_tag="ACN3HL_002865"
     CDS             42..>1292
                     /locus_tag="ACN3HL_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HHC8007642.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          400 a          256 c          251 g          385 t
ORIGIN      
        1 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
       61 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      121 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      181 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      241 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      301 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      361 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      421 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      481 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      541 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      601 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      661 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      721 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      781 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      841 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      901 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
      961 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1021 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1081 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1141 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1201 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
     1261 cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DBGZHO010000153         1246 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.165, whole genome shotgun sequence.
ACCESSION   DBGZHO010000153 DBGZHO010000000
VERSION     DBGZHO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.165"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            200..742
                     /locus_tag="ACN3HL_002866"
     CDS             200..742
                     /locus_tag="ACN3HL_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007643.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACN3HL_002867"
     CDS             898..>1246
                     /locus_tag="ACN3HL_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HHC8007644.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DBGZHO010000154         1213 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.166, whole genome shotgun sequence.
ACCESSION   DBGZHO010000154 DBGZHO010000000
VERSION     DBGZHO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.166"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..559
                     /locus_tag="ACN3HL_002868"
     CDS             <1..559
                     /locus_tag="ACN3HL_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007645.1"
                     /translation="KKFGAEKIFIEKQSGATITHRPIFQEALEFVRDQDIFIVEAIDR
                     LGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGNPHLDKFIKDLIIQILAMIAEQE
                     RTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQRRLVYENIVKDLNEGIAISKIA
                     KNYNITRQTIYRIKNDIEYNSNQMN"
     gene            complement(556..>1213)
                     /locus_tag="ACN3HL_002869"
     CDS             complement(556..>1213)
                     /locus_tag="ACN3HL_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007646.1"
                     /translation="QFLEELSGEEYRLFLNNNILKLISYAKKANSLSLVDNLDNLLPD
                     KLIYDENEDNSQKQIIIFELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPF
                     FTLINFMLYVKEHLGYDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYK
                     EQNIKTLELIKKNIKYYDPLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF
                     "
BASE COUNT          432 a          195 c          175 g          411 t
ORIGIN      
        1 gaaaaagttc ggcgcagaaa aaattttcat cgagaaacaa tctggagcaa cgattactca
       61 tcgaccgatt ttccaggaag ctttagagtt tgtccgagac caagatattt ttattgtcga
      121 agcaatcgac cgacttggaa gaaattacga cgaaatcatt gcttcagtca attacctaaa
      181 gaagaaaaac gtgcagctga tcatcaccag tctaccgatc atggctgaag caattggcaa
      241 tcctcatttg gataaattca ttaaagattt aatcatccaa attttggcca tgattgcaga
      301 gcaagagcgt accgaatcta aacgacgcca ggcgcaagtc attaaaattg caaaagcaaa
      361 tggcgtctat aaaggtcgtc caaaactcta tagtgcagat acaaaaaatc ctcaacgacg
      421 tttagtttat gaaaacatcg ttaaggattt aaatgagggc atagctattt caaaaattgc
      481 taaaaactac aatattacta gacaaactat ttacagaatt aagaatgata ttgagtataa
      541 cagtaatcaa atgaattaaa aaagttcttt atacattaaa atttcttctt ttaactcatc
      601 aattctagga gatctaacat cagaatcagc aattgcattt aataacttat caatattttc
      661 tttattcgct agtaaaggat catagtattt tatattcttt ttaattaatt ccagagtttt
      721 tatattttgt tctttgtaat tagctagaat ttcttctaca gtttcgcctg aaatcatagc
      781 catatctgaa ccagtattga ttcctttgaa tggataaggt tctttatcat atgcctttat
      841 catttctact aaatcatcat atcctaagtg ttctttaaca tacagcataa aatttattaa
      901 tgtaaaaaat ggcattgaag aatagtctgg aaatataaat tgaaacagtt tgttcgcaaa
      961 atatttatca tcatcattgc tttctggtga cactgacagg ctgctaagcc actttaaata
     1021 caattcaaat ataattattt gtttttgtga attatcttca ttctcatcat aaataagttt
     1081 atcgggtaaa agattatcta agttatctac taaagatagg ctattagctt tcttggcata
     1141 agatattaat tttaaaatat tattatttag gaataatcta tattcttctc cagataattc
     1201 ttctaaaaat tgt
//
LOCUS       DBGZHO010000155         1184 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.167, whole genome shotgun sequence.
ACCESSION   DBGZHO010000155 DBGZHO010000000
VERSION     DBGZHO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.167"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..861
                     /gene="mobL"
                     /locus_tag="ACN3HL_002870"
     CDS             <1..861
                     /gene="mobL"
                     /locus_tag="ACN3HL_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HHC8007647.1"
                     /translation="HIHIHFAVVEKENTRKPYTEVENGVSYIVPKGKRRQATLDAMKT
                     NYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYDRHAMNLLNEVYK
                     TLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQISKALKEEAKSL
                     YGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVDQMQSIYNERSFR
                     TLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEKYHASKAYEEQQ
                     RRIQMEQERQ"
     gene            882..>1184
                     /locus_tag="ACN3HL_002871"
     CDS             882..>1184
                     /locus_tag="ACN3HL_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007648.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT          484 a          178 c          243 g          279 t
ORIGIN      
        1 catatccata ttcattttgc agttgttgaa aaagaaaata cgcgtaaacc ttacacggag
       61 gttgaaaatg gtgtgagtta tatcgtaccg aaaggtaaga gaagacaagc aacattagac
      121 gcaatgaaga ccaattatgt acatgagtta gaacgttttt cttatgaaaa ggatcgaatg
      181 attggtatgg agaaacgaaa tttattgacg cggaaaagtg atttgcgtaa caccttaaca
      241 aaagtggtaa aagagccagc gcgttacgat cgacacgcga tgaacttatt aaatgaagta
      301 tataaaaccc tacctgacaa acgttcggaa tggaattacg gggatgaaaa acgaaccaaa
      361 ctttcaccat acacaagaga gaaactcgat gagttaacca aatatgtttt aacaaaagaa
      421 cctgaatatc aagaatatat acagatttca aaagcattga aagaagaagc aaaaagtctt
      481 tatggggaaa gcaagagaga atcaaaggat gcagagaaaa atgctctctt tgatttaaaa
      541 aagcgcacag gaaatgccat cctaacagag ctgaagagac aggatagtca aataaaacca
      601 ttaatagaaa gtgttgatca gatgcaatct atttacaatg aacgatcctt tcgaacgctt
      661 aaacaattgc caacgaatga atacaaatat agttacgaag aattcatgaa gcgcaggaaa
      721 caattccaac aaagagttgt cacgcagcgg agtttgcgtc aattaaatcg aacgattaat
      781 gcccatgaag aaaaatacca cgcaagtaaa gcatacgaag agcaacaacg aagaattcaa
      841 atggaacaag aaagacagta aagacagtag gaggaatagc aatgaaacaa tatttagatc
      901 aatggaaagt tatagaagga tcattaagag aagaacgaat cgaacaactt cctgattgtt
      961 tagaaaaaga gcatttgttc cagataagag aaatgttgag aaacgaacag tttgatccaa
     1021 atcaattttt agtcgttgag tacccagcta ctggtgtgta ttgttgtaat catgtgaatg
     1081 gtgaaaaata ttttatcatt caagaatatg agggcaagtt agcaccttat tatactactt
     1141 gggaaatgaa tgaagaggga atcaataact ttccatgtaa aagc
//
LOCUS       DBGZHO010000156         1159 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.168, whole genome shotgun sequence.
ACCESSION   DBGZHO010000156 DBGZHO010000000
VERSION     DBGZHO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.168"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(276..1157)
                     /gene="galU"
                     /locus_tag="ACN3HL_002872"
     CDS             complement(276..1157)
                     /gene="galU"
                     /locus_tag="ACN3HL_002872"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HHC8007649.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          295 a          258 c          180 g          426 t
ORIGIN      
        1 attaaaaaat tcgctttttt attctactat gaatcttctg gcttggcttt catttctctt
       61 atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca taatattttc
      121 tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa ctgatctaga
      181 gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt taataacaaa
      241 tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct tagcttttta
      301 ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg aagtccatat
      361 tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt tcctttaaac
      421 tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt tagctgtatc
      481 tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg agtcagtaga
      541 taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt ttctacaaac
      601 ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat tccgtattta
      661 gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt ttcttcataa
      721 tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc ccccagcatg
      781 acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc ccccagtcct
      841 cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc aactaaagcg
      901 agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt tgcatcaaag
      961 tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc gattcccgaa
     1021 tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg aagcatttct
     1081 tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc aggaatgact
     1141 gcttttttga ccttcactt
//
LOCUS       DBGZHO010000157         1137 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.169, whole genome shotgun sequence.
ACCESSION   DBGZHO010000157 DBGZHO010000000
VERSION     DBGZHO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.169"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..355
                     /locus_tag="ACN3HL_002873"
     CDS             <1..355
                     /locus_tag="ACN3HL_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007650.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..910
                     /locus_tag="ACN3HL_002874"
                     /pseudo
     CDS             615..910
                     /locus_tag="ACN3HL_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1137
                     /locus_tag="ACN3HL_002875"
     CDS             985..>1137
                     /locus_tag="ACN3HL_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HHC8007651.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          431 a          135 c          237 g          334 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggta
//
LOCUS       DBGZHO010000158         1062 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.171, whole genome shotgun sequence.
ACCESSION   DBGZHO010000158 DBGZHO010000000
VERSION     DBGZHO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.171"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(37..>1062)
                     /locus_tag="ACN3HL_002876"
     CDS             complement(37..>1062)
                     /locus_tag="ACN3HL_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HHC8007652.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DBGZHO010000159         1054 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.172, whole genome shotgun sequence.
ACCESSION   DBGZHO010000159 DBGZHO010000000
VERSION     DBGZHO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.172"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..>1054)
                     /locus_tag="ACN3HL_002877"
                     /note="aph(2'')-Ia"
     CDS             complement(<1..>1054)
                     /locus_tag="ACN3HL_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HHC8007653.1"
                     /translation="RYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIED
                     LPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVA
                     YLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGY
                     KEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEY
                     ILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTG
                     IIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYY
                     PIETIVYGIKNIKQEF"
BASE COUNT          352 a          175 c           81 g          446 t
ORIGIN      
        1 ataaattcct gtttaatatt tttaattcca taaacaatag tttcaatagg ataatattct
       61 tcaactatat cttgatattc ttttgctttc tcaatatcta tatttccata cattcttaat
      121 atatcttctc caaaatttgt tcctatttct tcttcactat cttcaagtaa gtatataaaa
      181 tcacaatatt catctataat tccagaatct ccaaaatcaa ttattccagt taatctatta
      241 ttgccatcta acaatagatg attacaacta aaatcattat ggcataaaca ctttttaccc
      301 tcaaaaactg ttgttgcatt tagtctttcc ataaaacttt ctatataatc tttttctata
      361 tcagttaaat cattataaat agtttcacgc aacaatatat actcttctaa tacattttgt
      421 ttattatcaa tagtacattc actaatatct gtataatcta aaccgtgcat ttgtcttaaa
      481 aaactggcaa tatctcgttt taacaaattt tgttcttctt ctgacatagt agaataaatt
      541 tctggtgtta aaaaagttcc tttaatttct ttataaccta gtatagataa ttcatcacta
      601 atatacgaat attcaatatt aggaattttt acattagttt ctaaatttgt atttaaaaaa
      661 ttatatattg ctttttcttt tgcataacct tttttcttat tagtactaaa ttttgtttta
      721 aaaatgtatt cattattaac taaatatgcc acactatcat aaccactacc gattatttca
      781 atactatcta ctttgaaatt atcaaagtaa tgctcaatta aatatttcat tgccttaaca
      841 tttgtggcat tatcatcata tctatattcc attaaataac aatcttcttt tttgccctcg
      901 tgtaattcat gttctggcaa atcttcaata attctaaaac cagatttttg gtatgccctt
      961 attgctcttg gattattttt atgagggtct aaaataactg cattagcatt tctttctttt
     1021 ttcaaaaatt caaaaatcaa tttaatatat cttg
//
LOCUS       DBGZHO010000160         1038 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.174, whole genome shotgun sequence.
ACCESSION   DBGZHO010000160 DBGZHO010000000
VERSION     DBGZHO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.174"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..>1038
                     /locus_tag="ACN3HL_002878"
     CDS             <1..>1038
                     /locus_tag="ACN3HL_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HHC8007654.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKH"
BASE COUNT          361 a          204 c          187 g          286 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacacc
//
LOCUS       DBGZHO010000161         1001 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.175, whole genome shotgun sequence.
ACCESSION   DBGZHO010000161 DBGZHO010000000
VERSION     DBGZHO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.175"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            370..1001
                     /locus_tag="ACN3HL_002879"
                     /pseudo
     CDS             370..1001
                     /locus_tag="ACN3HL_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          181 c          183 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccactac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DBGZHO010000162          992 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.176, whole genome shotgun sequence.
ACCESSION   DBGZHO010000162 DBGZHO010000000
VERSION     DBGZHO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.176"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            55..>992
                     /locus_tag="ACN3HL_002880"
     CDS             55..>992
                     /locus_tag="ACN3HL_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHC8007655.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTK"
BASE COUNT          355 a          180 c          189 g          268 t
ORIGIN      
        1 tttgtgctac actcaaaata gttccgacga aagaattata aggagtgagt acaaatgacc
       61 tataaccatc ttacaccaac tgaactcgta atgatagaag cttatttcaa tcaatcacaa
      121 cctgtttcaa aagtagccaa tctgttacaa cgttctcgac aaactattta taaggtctat
      181 cgttttctta aatctggtgg aagcgcaatg agctactata aacaatataa gaaaaacaaa
      241 cgtaactgcg gaagacatcc gattgtttta cctgatgagc aacaggaata cattcaaaaa
      301 aaggttgttc aagggtgggc tcctgatgtc cttattggtc gagcagagtt tcctattgct
      361 tgttcggtac gcacactgta tcgaatgttt aaagataaaa cctttgacac tcacgattta
      421 ccaatgaagg gaaaaagaaa accaaacggt cataaagaaa aaagaggaaa acaagggttt
      481 cgccggtcaa tccgagacag aaagacagac tatacccagt ttgatcatga atttggtcac
      541 ctggaaggtg acactatcgt gggtggaaaa cataaaagcg cggtcatcac attagttgaa
      601 cggctatcta aagtcatcat taccttgaaa cccgaaggca gacaggctaa agacattgaa
      661 aataggctga atcaatggtt tcgttgtgtc ccaaaaaact tatttaaatc catcacattt
      721 gattgtggaa aagaattctc aaattggaaa aagattagta ataccaacga tatttcaatt
      781 tattttgcgg atccaggaac accttctcaa cgaggattga atgaacattc aaatggctta
      841 ttacgtaaag atggtttgta taaagctatg gattttaatg gtgtatctga aacctttatc
      901 caatcggtgg catcgaaacg aaatcatatt cctagaaaat cattacacta tcggacacca
      961 atggaagtat ttttgagtta cgtcacaaaa ga
//
LOCUS       DBGZHO010000163          941 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.177, whole genome shotgun sequence.
ACCESSION   DBGZHO010000163 DBGZHO010000000
VERSION     DBGZHO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.177"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            68..141
                     /locus_tag="ACN3HL_002881"
     tRNA            68..141
                     /locus_tag="ACN3HL_002881"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:102..104,aa:Ile,seq:cat)
     gene            complement(654..>941)
                     /locus_tag="ACN3HL_002882"
     CDS             complement(654..>941)
                     /locus_tag="ACN3HL_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HHC8007656.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          298 a          153 c          160 g          330 t
ORIGIN      
        1 gcgataacag gtttgttgcc acacattcta ctggttgatt gtttatggct ttatgtggca
       61 acaaccagta cccttagctc agttggtcag agcagacggc tcataaccgt ccggtcgtag
      121 gttcgagtcc tacagggtac attaacgtag ccatttgaat cgttctgtgt tagaattttt
      181 tgaagagtat tatacaagct aaagcttttc ttcattgcca ctcaaatgag tggctttttt
      241 atgtatcctt ttatggatta atgaaaggat gtttcacata gttatatttc tgtatatttg
      301 aaaagtttta ctttgatttt taaatagaaa gacatttggg ttaaattgtg agatgataat
      361 aaagaagagt ttaaagcgca ccccaagcca cttccccata agtgtgttac gctttaaact
      421 cttttatatt tgaagctatt aaaaggcata ccatattttt gaaaaaaagt gagaaaaaag
      481 gcttacaatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
      541 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
      601 tcacaagtat ggtgataaaa ttcgttccgg gctacctttt taggtagcct actttaatct
      661 ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgcta
      721 cgtgcgtccg gcacgtcagt cacgatatca aacaaaaagt atacatcctt cttcattcta
      781 gttttcgcag caggaatttt gaaatagttc ttattagaat agtagagatt gattaataag
      841 ctatcttcga ttgctaaaaa gaaaacttct gaattccata ctttataaaa atctttgata
      901 aatctattcg aagggtcaaa tttaaaccat aattgtgtct c
//
LOCUS       DBGZHO010000164          933 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.178, whole genome shotgun sequence.
ACCESSION   DBGZHO010000164 DBGZHO010000000
VERSION     DBGZHO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.178"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            161..739
                     /gene="pgsA"
                     /locus_tag="ACN3HL_002883"
     CDS             161..739
                     /gene="pgsA"
                     /locus_tag="ACN3HL_002883"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HHC8007657.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
BASE COUNT          261 a          162 c          211 g          299 t
ORIGIN      
        1 aggatcgtga caaatctgtg tcgcggtcct tcttcgttaa ttcaaaaaga tcaatttcaa
       61 taaaaatact cctttgaata aattcatttg gaaaagtaaa taatatcggt ggaaacttcg
      121 ctgatagtca cgtagaatag ggaagaaagg agtcgatagt gtgaatttac caaataaatt
      181 aactgtactt agaatttgta tgatcccgat tttcattttg gttgtaggtt tacctttaga
      241 ttggggacaa tttaacgtag gagacaccac actggctgtc acacagctag taggtgcagt
      301 tatttttgct ttagctagta tcacagactg gttagatgga aaaattgccc gtgcgcgagg
      361 ccttgtcact aattttggca agtttgcgga cccgttggca gataaaatgc tagttatgac
      421 tgcttttatc atgttggttg accaaggaaa ggcccctggt tgggtagtag cgatcattgt
      481 ctgtcgtgaa ttagccgtca caggcttgcg tttactactt gtcgaacatg gagaagtcat
      541 ggctgcagct tggccgggaa aagtcaagac ggctacacaa atggttgcta ttatcttgct
      601 gtttatcaat aatatcccat tcagcctgat cggtattcca gtagatcaaa tcatgcttta
      661 tgcttgtctg atctttacta tctattcagg tgtggattac ttcatcaaaa acagcggtgt
      721 gttcaaagga tcaatgtaag tatcgtttag tggagaggtt gtgagcctgc cgtctaactc
      781 tgagtcacaa gggataattt caaaaaacag cttttcatgt tttatgtata ttgtgactta
      841 tgaccgaggt tttggcagga gaacactgtt tatttggaac aaggagctgt gacaagattt
      901 ttgtcacagc tccttgccct ctttttaaat aaa
//
LOCUS       DBGZHO010000165          915 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.179, whole genome shotgun sequence.
ACCESSION   DBGZHO010000165 DBGZHO010000000
VERSION     DBGZHO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.179"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(109..>915)
                     /locus_tag="ACN3HL_002884"
     CDS             complement(109..>915)
                     /locus_tag="ACN3HL_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HHC8007658.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDL
                     TYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          245 a          212 c          177 g          281 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcggc gccgactgag
      781 ttgaagccca cgctttgcta aacacttctt caattttcgg gtaccgtaag cctttcggtt
      841 tcgaataaac tcttcctgaa cgatctcttc taagtcggac tcattttcga tcggtttcgc
      901 ttgataatag taggt
//
LOCUS       DBGZHO010000166          896 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.180, whole genome shotgun sequence.
ACCESSION   DBGZHO010000166 DBGZHO010000000
VERSION     DBGZHO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.180"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            16..>896
                     /locus_tag="ACN3HL_002885"
     CDS             16..>896
                     /locus_tag="ACN3HL_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="HHC8007659.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQK"
BASE COUNT          291 a          178 c          167 g          260 t
ORIGIN      
        1 aaaggaggaa tcaagatgtc ttacactcac cttatcaaag aaacattaga tattctagac
       61 ttatcagtta cttttaacga aaattgtctc acaaaagaaa aatacaaagg gcaaatctgt
      121 catatttatc gtggaaactt gatttataca gcccaagaat gcatccactg taaacaccag
      181 attgcttcag atattgtgcg ttggggtaca acaaccgtcc ggttgttaat gaacgatgtt
      241 tctgaatacc gtacctacct cgaattgaaa aagcaacgct tcaaatgcaa agcttgtcag
      301 cggacctttg tcgcagatac ttctgttgcg aaaaaacatt gtttcatcag tgagaaagtc
      361 cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa tgacagagat cgccgctcag
      421 aaaaatctat cggtctcttc tgtttaccgt attatgaagc gattttatcg tccgttgaat
      481 ccttttcgga caccgttacc taaggtactt tgttttgatg aattcaaatc agttcggggt
      541 gtttcaggtg ctatgagttt catcatgatg gatggacaaa cacagcgctt attggacatt
      601 gtcgagaacc gacaactgcc ttttttaaaa cgttatttta gtcatttttc acgagaaatt
      661 cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc cttatgtatc gctcgttaaa
      721 aagctgtttc caaaagcaca gctgattatt gaccggtttc acatcgtcca acatattggt
      781 cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac tattaaaaag caaagaacaa
      841 aaacactatc aattaggtaa gcaattaaaa agatactgga aacttcttca aaaaga
//
LOCUS       DBGZHO010000167          876 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.181, whole genome shotgun sequence.
ACCESSION   DBGZHO010000167 DBGZHO010000000
VERSION     DBGZHO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.181"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            45..>876
                     /locus_tag="ACN3HL_002886"
     CDS             45..>876
                     /locus_tag="ACN3HL_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HHC8007660.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          304 a          153 c          167 g          252 t
ORIGIN      
        1 actcaaaata gttccgacca aagaattata aggagtgagt acaaatgacc tatacccatc
       61 ttacaacgga tgaacttgta ataatagagt cttatttcaa aatgaatcaa tctgttgcta
      121 aaactgccca ttgcttgaat cgttcaagac aaacgatcca taaagtatat ctgttcttca
      181 agcaaggaaa atcagcctta gaatattatc aacagtataa gaaaaacaaa tcaaactgtg
      241 gtagacgtcc gcttgtttta cccgaggaac aatcagaata tattcaaaga aaggttgttc
      301 aaggatggac acccgatgtg attgttggtc gtgcagcgtt tcctattagt tgttctgctc
      361 gtaccattta tcgtatgttc aaaaaggggc tatttgattc ttctgactta ccgatgaaag
      421 gcaagcgtaa accgaatgga catcaagaaa gacgtggaaa acaaactttc cgccgctcta
      481 ttcatgaacg tgaaaaggat tatagccaat tctcaaatga gtttggtcac cttgaaggtg
      541 acactatcgt aggtctgaaa cataaaagtg ctgtaattac cttagttgaa cgattatcaa
      601 aagttatcat cacattgaaa ccgtgtggta gacaagcgat tgatattgaa aaaaaattaa
      661 atcaatggtt tgaatctgta ccgaaaaacc tattcaaatc catcactttt gattgtggaa
      721 aggaattttc aaattggaaa cagatcagta atgtcaatga tattgccatt tatttcgctg
      781 atccaggaac gccgtctcaa agaggcctaa acgagaattc taacggattg ttacgtagag
      841 atggtttatt gaaatctatg gatttcaatt cagtag
//
LOCUS       DBGZHO010000168          863 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.182, whole genome shotgun sequence.
ACCESSION   DBGZHO010000168 DBGZHO010000000
VERSION     DBGZHO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.182"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..861
                     /locus_tag="ACN3HL_002887"
     CDS             <1..861
                     /locus_tag="ACN3HL_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HHC8007661.1"
                     /translation="EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPD
                     KYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKR
                     YKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIIS
                     YSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMS
                     RKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLS
                     PVEYRKQSIK"
BASE COUNT          374 a          112 c          140 g          237 t
ORIGIN      
        1 gagcaagaag aaatcaaggt taaaacaatc cttcagctca aaaaagaatt taaattgaat
       61 ctattacttt caattgcaca attagcgaag tcaacttatt attactgggt aaaaaaatta
      121 gataagccag ataaatatag caagataaag caagaaatta cagcgattgt aaaagaatca
      181 agaaactctt atggttatcg tagagtcact ttagcgttaa agatgaaagg atatacaatc
      241 aatcataaaa cagttagaaa attaatgtcc caaatgggac ttacctgtca aatccgaata
      301 aagcgatata aatcttataa aggaacagta ggaaaaattg ccaagaatgt gttaaaacga
      361 aatttttcag tagatacacc caataaaaaa tgggtgacag acgtcactga attcaagata
      421 aaaggaagaa aaatctatct atctcctata cttgatttat ttaacggaga aataattagt
      481 tatagtatat caactagtcc aacatataaa ctgattgaag aaatgcttca acaagcaatt
      541 aaaaaaaagg gaactgaggg ttcactgatt ctacattcag atcaaggatg gcagtatcag
      601 atgccacaat atcaaaaaaa attaaaagag aataacatta ttcaaagcat gtctagaaaa
      661 ggaaattgct tagataattc tgtaatagaa aatttttttg gtgtgcttaa atcagagttt
      721 ttttatcgag aaaaattccg atcaattgag atatttcaaa gtaaattaaa tgagtatatt
      781 aggtggtata ataacaaaag gataaaacta aagttaaatg gactatctcc agtagaatat
      841 cggaaacagt ccattaaata gtt
//
LOCUS       DBGZHO010000169          854 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.183, whole genome shotgun sequence.
ACCESSION   DBGZHO010000169 DBGZHO010000000
VERSION     DBGZHO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.183"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            82..>854
                     /locus_tag="ACN3HL_002888"
     CDS             82..>854
                     /locus_tag="ACN3HL_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HHC8007662.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQA"
BASE COUNT          283 a          159 c          166 g          246 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgtt
//
LOCUS       DBGZHO010000170          823 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.184, whole genome shotgun sequence.
ACCESSION   DBGZHO010000170 DBGZHO010000000
VERSION     DBGZHO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.184"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            154..417
                     /locus_tag="ACN3HL_002889"
     CDS             154..417
                     /locus_tag="ACN3HL_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HHC8007663.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACN3HL_002890"
     CDS             417..689
                     /locus_tag="ACN3HL_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HHC8007664.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
BASE COUNT          315 a          108 c          164 g          236 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag att
//
LOCUS       DBGZHO010000171          811 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.185, whole genome shotgun sequence.
ACCESSION   DBGZHO010000171 DBGZHO010000000
VERSION     DBGZHO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.185"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            178..774
                     /locus_tag="ACN3HL_002891"
     CDS             178..774
                     /locus_tag="ACN3HL_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HHC8007665.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          233 a          122 c          150 g          306 t
ORIGIN      
        1 ttaaaaaaaa caagttatta aataagtctt tagttggatg tttttttgag atcaatcttt
       61 tatacttatg atgaacttac aaaattgttt gttttctgtc atatcaaaaa atggcgcagt
      121 tagttgcttt tctagtaaag tatagttaac aaagaacctc taaggagttg atgaataatg
      181 aatattgctg cctctcgaaa actgataaat ttcatatcca ttatcggatt aggcctatca
      241 atcgcgctga cgatttattt tattaattta ggtgttttca aagatttgaa tgcgttaaga
      301 ggattagtag gtgattccat cattttagga ccgattattt ttgtcttcat ccaaatcctg
      361 caagtagtta ttccaatcat tcctggaggg atcagtactg cagctggtgt cctgatattt
      421 ggcccttatg ctggatttat ctataactat attggaatct gcattggttc gattatcatt
      481 tttctgctag ggcgtcgtta tggaaagcca ttcatacttt ccatgattag cgataagaca
      541 tataacaaat atattggctg gctggataat caaaaccgtt ttgagaagct gtttgctcta
      601 gctatttttc ttccagttgc tcctgacgat gcgttatgtt tgatggctgg attgacaaac
      661 atgtcagtga aacgatatac actaatcatt ttgattgcta aaccactgtc gattttctta
      721 tatagtatgg ccttgattta tggaggtcaa tatctaagtg gtcttcttgg ataatattta
      781 ttttgtaaaa ttagtcattg attgacaatg t
//
LOCUS       DBGZHO010000172          801 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.186, whole genome shotgun sequence.
ACCESSION   DBGZHO010000172 DBGZHO010000000
VERSION     DBGZHO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.186"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..672
                     /locus_tag="ACN3HL_002892"
     CDS             <1..672
                     /locus_tag="ACN3HL_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HHC8007666.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          296 a          125 c          149 g          231 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac c
//
LOCUS       DBGZHO010000173          792 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.187, whole genome shotgun sequence.
ACCESSION   DBGZHO010000173 DBGZHO010000000
VERSION     DBGZHO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.187"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..781
                     /locus_tag="ACN3HL_002893"
     CDS             <1..781
                     /locus_tag="ACN3HL_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8007667.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          339 a          107 c          102 g          244 t
ORIGIN      
        1 agatatgcta gattactact attttgaaaa aaatttatca tataattatg taatacattt
       61 aaaaactttt acaggaatga tttttaaatt cgccaaccgt cgatatggat taaaatataa
      121 tcccgtaaat ggggtttctt tagcaagaaa acctaagaca aacgaagaaa taaaaaaaga
      181 aaaagatggt tatttatcaa aagaagaagt tcaaatgatt gctagtaaac aaaaaagttc
      241 acatcaacag tcacgttatt ctttaattac taaatttttg tttttaactg gactacgtta
      301 tggtgaattg atatctttga ctgaatctga ttatgatggt aataaaatta cggtttctgg
      361 tacttatgat tacgagttaa aaattaaaac aacaactaaa aatacaggtt cttatagaac
      421 cattgaatta tcaagtaatg ctaaagaaat catagatcaa ttaattgaag aaaacaaatt
      481 aattaagaat aataaagata aatacatttt catctctaaa aatggtaacc cgatatctat
      541 tcaagcatat aatcaatctt taagagcagt atccaaagaa ttaaacatag ataaaaaagt
      601 ttcttctcac atgttaaggc attcccacat ttctctactt acagaattag gaatcccatt
      661 aaaagccatt atggatcgtg taggacatga agattcaaaa acaacattaa agatttatac
      721 tcatacaact aaaaatatgc aaaatcaact agtagaaaaa ctaggaaaaa tagaaattta
      781 aattgcccct tt
//
LOCUS       DBGZHO010000174          768 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.188, whole genome shotgun sequence.
ACCESSION   DBGZHO010000174 DBGZHO010000000
VERSION     DBGZHO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.188"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACN3HL_002894"
     CDS             complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACN3HL_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HHC8007668.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          222 a          156 c          135 g          255 t
ORIGIN      
        1 cgtccaaata atttgttggt taaataattg accttttcat tcaatagttg gatttcagtt
       61 gtaagattct gaatggtttg ttgttgtgct tgattggttt tatgggcttc ttgaagcaac
      121 tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa ctgattttgt
      181 tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt tgtgttaacc
      241 ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga tcgatactta
      301 atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg tctttcgtcc
      361 gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa ccatcaccgt
      421 cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa acggcatctt
      481 cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca attccttttc
      541 gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa tcataaagca
      601 ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc gttatagatc
      661 aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc cgcgggttta
      721 cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatc
//
LOCUS       DBGZHO010000175          743 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.189, whole genome shotgun sequence.
ACCESSION   DBGZHO010000175 DBGZHO010000000
VERSION     DBGZHO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.189"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            136..>743
                     /locus_tag="ACN3HL_002895"
     CDS             136..>743
                     /locus_tag="ACN3HL_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HHC8007669.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT          244 a          129 c          144 g          226 t
ORIGIN      
        1 gctctataat ttatgggact gatgaatcag aattgattct tcagccccat ttttatttta
       61 ggtattaaaa aacatatcgt tctctagtat gattaaatca cgacaaaata aacaactgag
      121 aggacgatat gctatatgaa tgattctatc aaaaaaatgc tgcgattaat agagaaagat
      181 ttgatgatta cagaggtctc ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat
      241 gctgttttct cacctgctcc ccatacctgt agaaattgtg gttctactgt ggtagatgga
      301 aacgggaaag taattgtagt gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa
      361 tacaatcaca tgcctttggt tatgcgctta aaaaagcagc gctatacctg taaaaactgt
      421 cgaacccatt ggacggctca aagttatttt gttcaaccca gacattcaat cgcgaatcat
      481 gtcagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      541 aattgtcagg tatctttgac caccgttatt cgtacgttga aagagtttaa aagctactta
      601 ccaaagcaat ctaagaggat tctccccaga gtattgatgg ttgatgaatt tcgttcgcac
      661 gcttccatag aagataaaat gagctttatt tgcgcagatg gcgaaacagg acaattaatt
      721 gatgtcttgc ctacgcgtaa att
//
LOCUS       DBGZHO010000176          728 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.190, whole genome shotgun sequence.
ACCESSION   DBGZHO010000176 DBGZHO010000000
VERSION     DBGZHO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.190"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            74..403
                     /locus_tag="ACN3HL_002896"
     CDS             74..403
                     /locus_tag="ACN3HL_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HHC8007670.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            393..680
                     /locus_tag="ACN3HL_002897"
     CDS             393..680
                     /locus_tag="ACN3HL_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HHC8007671.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          275 a           82 c          139 g          232 t
ORIGIN      
        1 cttgtaaata cattatctcg tggtataatg tatttactaa gtaattacat actgttagaa
       61 atgagggatt taaatgatta caaaaacaag aaaacaaggc aattcaatca tgttgacagt
      121 acctaaagat tttaatgttc ctaatggagt cgaagttgaa gcaaagttgg tagagaatgg
      181 tattctttat gaatttgttg aaccacaaaa agaattttat gattttagcg aagatatttt
      241 gtctgatata attgcagaag gctacgataa agatgagatt cttgtagaat ttaagaatag
      301 aaaaaacaaa atgcattctt cctttagaga tattgctgaa gatacactta ctaattctaa
      361 agtaatgact aaagaggagt tggcaacaga aattggctta tgaaatcgtt ccttcaaaac
      421 atgtcattaa gtatttaaaa aagctaaaag agaagccatt gaaagaaaaa tttttgaatt
      481 taatttatga tgaaattgcg attgatccat ataagggtga acaaaaaact ggggatttat
      541 caggtatttg gtctagtggg ttcaaatatg cgggcacaac atatagagta gcttacgaga
      601 ttatagaaaa caaggttatt ccagtattgt tatgtggaac gcatgaaaac ttttatgaac
      661 agttgaaaaa attaatctag tgatttgttg tcgttcttaa gaaggacggc ttctttttat
      721 cgaaaatc
//
LOCUS       DBGZHO010000177          713 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.191, whole genome shotgun sequence.
ACCESSION   DBGZHO010000177 DBGZHO010000000
VERSION     DBGZHO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.191"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..448)
                     /locus_tag="ACN3HL_002898"
     CDS             complement(<1..448)
                     /locus_tag="ACN3HL_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007672.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT          216 a          123 c           95 g          279 t
ORIGIN      
        1 tcaactttct cttttcaaaa aaaatttgat atttttttag atttcttttt agtctttgta
       61 atactttata agccacagaa taactcacgt gatgctgttt agcaaaattt tctactgaga
      121 tatatttttc ctgaaagaaa gccaatacca ttttcataga taaagaatcc gttatataac
      181 gagataacag agctttgcta gaacattttc cattaatttc cagacatata tccaattcac
      241 tgacggttac tcgcaaattt ttctctagat cgaacttttg taaatcatgt ttcagcttat
      301 cgatcgtttt tttcaagaga aatgtcgata gcgacaactc ttcttgaaca ttcgatattg
      361 actctgataa atttgagctt gcttctaaat atttaagtaa tgaataactt ctgtgatctt
      421 ctttgcttaa aaaaaactca taattcatta gtcatcagct ctttctacgt atattacttt
      481 ccatgcattc accaactagc tggggataaa actgatttcc tggatccgag tcactgttgt
      541 cagcgattct tgtttgtata atatacatcg tcctgtcttt tttttaacat tttggagagc
      601 gttttatttg gcctttctcg cgatcaaacc tgttattaga attatatcat ttactagtat
      661 gcatttttat taataaaatg gtatatttta tattgttata aaaagagccc aac
//
LOCUS       DBGZHO010000178          696 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.192, whole genome shotgun sequence.
ACCESSION   DBGZHO010000178 DBGZHO010000000
VERSION     DBGZHO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.192"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(53..628)
                     /locus_tag="ACN3HL_002899"
     CDS             complement(53..628)
                     /locus_tag="ACN3HL_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HHC8007673.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DBGZHO010000179          639 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.193, whole genome shotgun sequence.
ACCESSION   DBGZHO010000179 DBGZHO010000000
VERSION     DBGZHO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.193"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..282
                     /locus_tag="ACN3HL_002900"
     CDS             <1..282
                     /locus_tag="ACN3HL_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HHC8007674.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          213 t
ORIGIN      
        1 ttaatacaag atgatttaca ccatacgcat cggttatggt taatgaataa aattaatctg
       61 tattttgggc attcttatgt ttttgctttt tatgattaca ggacaaatat aactgaagta
      121 gatttggtta tttctaatta ctacatcgac actggaaaaa cgccattact gttaatgaaa
      181 aatataccta ccgaaagaaa ctggcgtttg ttcgagaaaa cgatttatca attgaaaaaa
      241 gaaaaagagg ttgtgaaatc agcgttttgt cctgagtatt agagaaacaa acggaaaaat
      301 agtttttcat attttgccgt ttttgagcta ataccgaggg acagctgatt gaacaccatt
      361 tattgagaga ttgtgaaaaa actgtcctgc atcaagtaat aagaacagcc aagtaaaaac
      421 agcttctcat gtttgttgaa tattgtgact tgtgaccgag gagttggcaa gagaacaccg
      481 tttattcgga aaaagggact gtgacactac atgtcacagt ccctttttga ttgaattatc
      541 tcatttgttt tctaattttt tctttatttg agaaaatagt tgaactggat aaaaagtact
      601 ggacgtgtca aaattatttt ggatcaaatt agatctatt
//
LOCUS       DBGZHO010000180          618 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.194, whole genome shotgun sequence.
ACCESSION   DBGZHO010000180 DBGZHO010000000
VERSION     DBGZHO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.194"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
BASE COUNT          274 a           89 c          100 g          155 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgcta
//
LOCUS       DBGZHO010000181          560 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.195, whole genome shotgun sequence.
ACCESSION   DBGZHO010000181 DBGZHO010000000
VERSION     DBGZHO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.195"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..>560
                     /locus_tag="ACN3HL_002901"
     CDS             <1..>560
                     /locus_tag="ACN3HL_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HHC8007675.1"
                     /translation="DMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNE
                     LRKVGQKSQAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGF
                     STSLKEAYPYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNA
                     MIYPYTNGKIEAKNTHIKTMKRVSYG"
BASE COUNT          193 a          118 c          107 g          142 t
ORIGIN      
        1 agacatgaac gccgcctact tccagcttac caaacgtatt ctgccaaatg cgaaagtagt
       61 gattgatcgg tttcatatta tcaaacacat gaatcaagcc tttaatgagt tgcgtatccg
      121 tgaaatgaat gaacttcgta aagtaggaca gaaaagtcag gcagaaaaac tgaaaaagaa
      181 ctggcgcttt ttgctaaaaa atcgtgcaaa catcaaccat tatgaataca aaacatggaa
      241 aagttttcga gcaccaaaat acccatttct tacggaagcg atgatgattg atcgattgct
      301 tggcttttct acgtccctga aggaggcgta tccctatttt catgaattag ttgaagcctt
      361 tcgagacaaa gaccctgact tatttttctc cttattggca gaacttcccg aaacgttaga
      421 tgacggcttt cgggaaaagc tccaaaacct tctgacctat gaagaaggca tcaccaacgc
      481 gatgatctat ccttacacca atggaaaaat agaagcgaag aatacccata taaagacaat
      541 gaaacgagta tcctacggat
//
LOCUS       DBGZHO010000182          560 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.196, whole genome shotgun sequence.
ACCESSION   DBGZHO010000182 DBGZHO010000000
VERSION     DBGZHO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.196"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
BASE COUNT          187 a           88 c           87 g          198 t
ORIGIN      
        1 gaagagtatt atacaagcta aagcttttct tcattgccac tcaaatgagt ggctttttta
       61 tgtatccttt tatggattaa tgaaaggatg tttcacatag ttatacttct gtatatttga
      121 aaagttttac tttgattttt aaatagaaag acatttgggt taaattgtga gataataata
      181 aagaagagtt taaagcgcac cccaaaccac ttccccataa gtgtgttacg ctttaaactc
      241 ttttatattt gaagccatta aaaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttacaattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
      361 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatctccttt
      421 cacaagtatg gtgataaaat tcgttccggg ctaccttttt aggtagccta ctttaatctt
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
      541 gtgcgtccgg cacgtcagtc
//
LOCUS       DBGZHO010000183          548 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.197, whole genome shotgun sequence.
ACCESSION   DBGZHO010000183 DBGZHO010000000
VERSION     DBGZHO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.197"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..>548)
                     /locus_tag="ACN3HL_002902"
     CDS             complement(<1..>548)
                     /locus_tag="ACN3HL_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HHC8007676.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQE"
BASE COUNT          147 a          119 c           84 g          198 t
ORIGIN      
        1 tcctcttgtt cgagttccaa tgcttctaat gatttaccgg acatatattt ctctaaaagg
       61 tcatcgtttc cctctattac cgtatcccat tgttcagatt cggtaaagtt cgtcacacac
      121 atattaggat acagttctac cttctgtttg attacaattt cggcagaaag tttctcttta
      181 atatcctgat aaaccgttga taaatcaatt ccattttggt caatcttatt gataaaaaag
      241 attgtgggaa tccccatttt cctaagtgca tgaaataata tacgagtttg tgcttgtacg
      301 ccatcttttg cagaaatcag tagaattgcc ccatctaaaa ctgataatga acgatatact
      361 tctgctaaga aatccatatg tcctggcgtg tctatgatgt tcaccttcgt attttcccac
      421 tgaaaagagg ttattcctgt ctgaattgta attcctctct gacgttctaa aagcgtatta
      481 tccgtcctcg ttgtaccttt gtccacgctt cctaattctg taatcgctcc actgttatat
      541 aataagct
//
LOCUS       DBGZHO010000184          528 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.198, whole genome shotgun sequence.
ACCESSION   DBGZHO010000184 DBGZHO010000000
VERSION     DBGZHO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.198"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(5..90)
                     /locus_tag="ACN3HL_002903"
     tRNA            complement(5..90)
                     /locus_tag="ACN3HL_002903"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="ACN3HL_002904"
     tRNA            complement(107..178)
                     /locus_tag="ACN3HL_002904"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="ACN3HL_002905"
     tRNA            complement(190..262)
                     /locus_tag="ACN3HL_002905"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="ACN3HL_002906"
     tRNA            complement(280..361)
                     /locus_tag="ACN3HL_002906"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="ACN3HL_002907"
     tRNA            complement(369..441)
                     /locus_tag="ACN3HL_002907"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="ACN3HL_002908"
     tRNA            complement(445..517)
                     /locus_tag="ACN3HL_002908"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DBGZHO010000185          526 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.199, whole genome shotgun sequence.
ACCESSION   DBGZHO010000185 DBGZHO010000000
VERSION     DBGZHO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.199"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..354
                     /locus_tag="ACN3HL_002909"
     CDS             <1..354
                     /locus_tag="ACN3HL_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HHC8007677.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
BASE COUNT          209 a           75 c          115 g          127 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacaga
//
LOCUS       DBGZHO010000186          524 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.200, whole genome shotgun sequence.
ACCESSION   DBGZHO010000186 DBGZHO010000000
VERSION     DBGZHO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.200"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(152..346)
                     /locus_tag="ACN3HL_002910"
     CDS             complement(152..346)
                     /locus_tag="ACN3HL_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007678.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          163 a          110 c           79 g          172 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caat
//
LOCUS       DBGZHO010000187          519 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.201, whole genome shotgun sequence.
ACCESSION   DBGZHO010000187 DBGZHO010000000
VERSION     DBGZHO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.201"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            23..>519
                     /locus_tag="ACN3HL_002911"
     CDS             23..>519
                     /locus_tag="ACN3HL_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HHC8007679.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          189 a           95 c           86 g          149 t
ORIGIN      
        1 tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc aaactctagt
       61 cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga taaacacact
      121 cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca ctggttttaa
      181 ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat atggtgaatt
      241 aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt taccagccta
      301 caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa aaggtgttac
      361 gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata ctccacaaac
      421 catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat ccagagcctt
      481 aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DBGZHO010000188          517 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.202, whole genome shotgun sequence.
ACCESSION   DBGZHO010000188 DBGZHO010000000
VERSION     DBGZHO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.202"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            57..>517
                     /locus_tag="ACN3HL_002912"
     CDS             57..>517
                     /locus_tag="ACN3HL_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HHC8007680.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          191 a           72 c          105 g          149 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaa
//
LOCUS       DBGZHO010000189          509 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.203, whole genome shotgun sequence.
ACCESSION   DBGZHO010000189 DBGZHO010000000
VERSION     DBGZHO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.203"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..132)
                     /locus_tag="ACN3HL_002913"
     CDS             complement(<1..132)
                     /locus_tag="ACN3HL_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HHC8007681.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DBGZHO010000190          478 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.denovo.204, whole genome shotgun sequence.
ACCESSION   DBGZHO010000190 DBGZHO010000000
VERSION     DBGZHO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.denovo.204"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..461
                     /locus_tag="ACN3HL_002914"
     CDS             <1..461
                     /locus_tag="ACN3HL_002914"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HHC8007682.1"
                     /translation="DLDALQVVSVVSFYESFIDGADPLDMQGYLQTQLTTEILAVELA
                     QSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLGQRLLDEANRYAKT
                     KQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPILEKEI"
BASE COUNT          173 a           70 c           89 g          146 t
ORIGIN      
        1 atgatctaga tgctttacaa gttgtaagtg ttgtcagttt ttatgaatcg tttatcgatg
       61 gcgcagatcc acttgatatg caaggatatt tacagacaca attgacaact gaaatattgg
      121 cagtagaatt ggcacagtca accagtaaat ttattggtat taaggatcat caaatactca
      181 ttggttatat gaaagtcaat gatgaaaaag atgctataga gattcaacgg ctctatctgc
      241 tcaaagatta tcaaaacaaa gggttagggc aacggttact cgatgaagcg aatcgttatg
      301 ctaaaacgaa acaaaaacgt tatttacgtt tgactgttta tgaaaaaaat catgcaggta
      361 ttcgttttta tgaacgtcat ggatttaaaa aaatcgggat caaacatttt cctttaggaa
      421 aacaagatcg tatttgtccg attttagaaa aagaaatcta aaaaaacgtc ctcacttt
//
LOCUS       DBGZHO010000191        20985 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.050, whole genome shotgun sequence.
ACCESSION   DBGZHO010000191 DBGZHO010000000
VERSION     DBGZHO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.050"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(134..577)
                     /locus_tag="ACN3HL_002915"
     CDS             complement(134..577)
                     /locus_tag="ACN3HL_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HHC8007683.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="ACN3HL_002916"
     CDS             complement(795..2135)
                     /locus_tag="ACN3HL_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HHC8007684.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="ACN3HL_002917"
     CDS             2404..3300
                     /locus_tag="ACN3HL_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HHC8007685.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTSFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="ACN3HL_002918"
     CDS             complement(3450..4391)
                     /locus_tag="ACN3HL_002918"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HHC8007686.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="ACN3HL_002919"
     CDS             4517..5638
                     /locus_tag="ACN3HL_002919"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HHC8007687.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACN3HL_002920"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACN3HL_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HHC8007688.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="ACN3HL_002921"
     CDS             7465..7992
                     /locus_tag="ACN3HL_002921"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HHC8007689.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="ACN3HL_002922"
     CDS             8203..9264
                     /locus_tag="ACN3HL_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HHC8007690.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="ACN3HL_002923"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="ACN3HL_002923"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HHC8007691.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="ACN3HL_002924"
     CDS             10177..12159
                     /locus_tag="ACN3HL_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HHC8007692.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACN3HL_002925"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACN3HL_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HHC8007693.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="ACN3HL_002926"
     CDS             12881..14305
                     /locus_tag="ACN3HL_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HHC8007694.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="ACN3HL_002927"
     CDS             complement(14486..15259)
                     /locus_tag="ACN3HL_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HHC8007695.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="ACN3HL_002928"
     CDS             complement(15256..16161)
                     /locus_tag="ACN3HL_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007696.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="ACN3HL_002929"
     CDS             complement(16315..16635)
                     /locus_tag="ACN3HL_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HHC8007697.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="ACN3HL_002930"
     CDS             17109..17795
                     /locus_tag="ACN3HL_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HHC8007698.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="ACN3HL_002931"
     CDS             17797..18741
                     /locus_tag="ACN3HL_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HHC8007699.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="ACN3HL_002932"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="ACN3HL_002932"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HHC8007700.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="ACN3HL_002933"
     CDS             19663..20940
                     /locus_tag="ACN3HL_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007701.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6776 a         3779 c         4365 g         6065 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggtgttccag
       61 aagtagcttc ttcttatttc ttgaagctga tcacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg gatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgt caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gttccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaataacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat ggctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgattagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccgccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa gcgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttaat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacatc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgtat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattgtttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaacga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcaccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DBGZHO010000192        20862 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.051, whole genome shotgun sequence.
ACCESSION   DBGZHO010000192 DBGZHO010000000
VERSION     DBGZHO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.051"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            267..1304
                     /locus_tag="ACN3HL_002934"
     CDS             267..1304
                     /locus_tag="ACN3HL_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HHC8007702.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="ACN3HL_002935"
     CDS             complement(1393..1716)
                     /locus_tag="ACN3HL_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HHC8007703.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="ACN3HL_002936"
     CDS             complement(1703..2410)
                     /locus_tag="ACN3HL_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HHC8007704.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="ACN3HL_002937"
     CDS             2496..2837
                     /locus_tag="ACN3HL_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HHC8007705.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="ACN3HL_002938"
     CDS             complement(3008..3856)
                     /locus_tag="ACN3HL_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HHC8007706.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="ACN3HL_002939"
     CDS             4454..5317
                     /locus_tag="ACN3HL_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHC8007707.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="ACN3HL_002940"
     CDS             5417..5899
                     /locus_tag="ACN3HL_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HHC8007708.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="ACN3HL_002941"
     CDS             complement(6162..6629)
                     /locus_tag="ACN3HL_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HHC8007709.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="ACN3HL_002942"
     CDS             6752..7603
                     /locus_tag="ACN3HL_002942"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8007710.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /gene="nagE"
                     /locus_tag="ACN3HL_002943"
     CDS             complement(7854..9812)
                     /gene="nagE"
                     /locus_tag="ACN3HL_002943"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HHC8007711.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="ACN3HL_002944"
     CDS             complement(9809..10681)
                     /locus_tag="ACN3HL_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HHC8007712.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="ACN3HL_002945"
     CDS             complement(11023..11895)
                     /locus_tag="ACN3HL_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HHC8007713.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="ACN3HL_002946"
     CDS             12023..12592
                     /locus_tag="ACN3HL_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HHC8007714.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="ACN3HL_002947"
     CDS             12659..13396
                     /locus_tag="ACN3HL_002947"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HHC8007715.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="ACN3HL_002948"
     CDS             13627..14895
                     /locus_tag="ACN3HL_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HHC8007716.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="ACN3HL_002949"
     CDS             15382..15846
                     /locus_tag="ACN3HL_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HHC8007717.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="ACN3HL_002950"
     CDS             15830..16459
                     /locus_tag="ACN3HL_002950"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HHC8007718.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="ACN3HL_002951"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="ACN3HL_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HHC8007719.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="ACN3HL_002952"
     CDS             18338..18784
                     /locus_tag="ACN3HL_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HHC8007720.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="ACN3HL_002953"
     CDS             complement(18983..19498)
                     /locus_tag="ACN3HL_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HHC8007721.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="ACN3HL_002954"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="ACN3HL_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DBGZHO010000193        20283 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.053, whole genome shotgun sequence.
ACCESSION   DBGZHO010000193 DBGZHO010000000
VERSION     DBGZHO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.053"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1168
                     /locus_tag="ACN3HL_002955"
     CDS             <1..1168
                     /locus_tag="ACN3HL_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HHC8007722.1"
                     /translation="YILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTEMY
                     TSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVEPS
                     KPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEI
                     ELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYL
                     NQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLTPIVLEQA
                     FRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARC
                     IQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            1266..1454
                     /locus_tag="ACN3HL_002956"
     CDS             1266..1454
                     /locus_tag="ACN3HL_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HHC8007723.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1512..1865)
                     /locus_tag="ACN3HL_002957"
     CDS             complement(1512..1865)
                     /locus_tag="ACN3HL_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007724.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2396..2818
                     /locus_tag="ACN3HL_002958"
     CDS             2396..2818
                     /locus_tag="ACN3HL_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HHC8007725.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2815..3045
                     /locus_tag="ACN3HL_002959"
     CDS             2815..3045
                     /locus_tag="ACN3HL_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HHC8007726.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3543..3743
                     /locus_tag="ACN3HL_002960"
     CDS             3543..3743
                     /locus_tag="ACN3HL_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HHC8007727.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3770..4963
                     /locus_tag="ACN3HL_002961"
     CDS             3770..4963
                     /locus_tag="ACN3HL_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HHC8007728.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5031..6596)
                     /gene="guaA"
                     /locus_tag="ACN3HL_002962"
     CDS             complement(5031..6596)
                     /gene="guaA"
                     /locus_tag="ACN3HL_002962"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HHC8007729.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(6655..7578)
                     /gene="coaA"
                     /locus_tag="ACN3HL_002963"
     CDS             complement(6655..7578)
                     /gene="coaA"
                     /locus_tag="ACN3HL_002963"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HHC8007730.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7774..8379
                     /locus_tag="ACN3HL_002964"
     CDS             7774..8379
                     /locus_tag="ACN3HL_002964"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8007731.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            8687..9703
                     /locus_tag="ACN3HL_002965"
     CDS             8687..9703
                     /locus_tag="ACN3HL_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HHC8007732.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9844..11145
                     /locus_tag="ACN3HL_002966"
     CDS             9844..11145
                     /locus_tag="ACN3HL_002966"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HHC8007733.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            11191..11853
                     /gene="deoC"
                     /locus_tag="ACN3HL_002967"
     CDS             11191..11853
                     /gene="deoC"
                     /locus_tag="ACN3HL_002967"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HHC8007734.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11874..12272
                     /locus_tag="ACN3HL_002968"
     CDS             11874..12272
                     /locus_tag="ACN3HL_002968"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HHC8007735.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            12338..13420
                     /locus_tag="ACN3HL_002969"
     CDS             12338..13420
                     /locus_tag="ACN3HL_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HHC8007736.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            13632..15194
                     /locus_tag="ACN3HL_002970"
     CDS             13632..15194
                     /locus_tag="ACN3HL_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HHC8007737.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            15187..16320
                     /locus_tag="ACN3HL_002971"
     CDS             15187..16320
                     /locus_tag="ACN3HL_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007738.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            16320..17276
                     /locus_tag="ACN3HL_002972"
     CDS             16320..17276
                     /locus_tag="ACN3HL_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HHC8007739.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            17375..18541
                     /gene="deoB"
                     /locus_tag="ACN3HL_002973"
     CDS             17375..18541
                     /gene="deoB"
                     /locus_tag="ACN3HL_002973"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HHC8007740.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            18565..19383
                     /locus_tag="ACN3HL_002974"
     CDS             18565..19383
                     /locus_tag="ACN3HL_002974"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHC8007741.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            19400..20107
                     /gene="deoD"
                     /locus_tag="ACN3HL_002975"
     CDS             19400..20107
                     /gene="deoD"
                     /locus_tag="ACN3HL_002975"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HHC8007742.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         6497 a         3640 c         4352 g         5794 t
ORIGIN      
        1 gtacattttg tcattttgta ctccaaaact gaactactta cttgcatata tacgccttta
       61 tagtggagta ctacatttac gagattcggt tagagtatca gaaaaagaaa aaataaaagt
      121 tacagaaatg tatacttcaa taaatggtga attatgtaag attgatagag cttattctgg
      181 agaaattgtt attttgcaaa atgagttttt gaagttaaat agtgttcttg gagatacaaa
      241 actattgcca cagagaaaaa agattgaaaa tccgcaccct ctactacaaa caactgttga
      301 accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc cttttggaaa tctcagatag
      361 tgatccgctt ctacgatatt acgtggattc tacgacacat gaaattatac tttctttctt
      421 agggaaagta caaatggaag tgattagtgc actgttgcaa gaaaagtatc atgtggagat
      481 agaactaaaa gagcctacag tcatttatat ggagagaccg ttaaaaaatg cagaatatac
      541 cattcacatc gaagtgccgc caaatccttt ctgggcttcc attggtttat ctgtatcacc
      601 gcttccgttg ggaagtggaa tgcagtatga gagctcggtt tctcttggat acttaaatca
      661 atcatttcaa aatgcagtta tggaagggat acgctatggt tgcgaacaag gattatatgg
      721 ttggaatgtg acggattgta aaatctgttt taagtacggt ttatactata gccctgttag
      781 tactccagca gattttcgga tgcttactcc tattgtactg gagcaagcct ttagaaaagc
      841 tggaacagaa ttgttagagc catatcttag ttttaaagtt tatgcaccac aggaatatct
      901 ttcacgggca tataacgatg ctcccaaata ttgtgcaaat atcgtaaata ctcaactgaa
      961 aaataatgag gtcattatta ttggagaaat tcctgctcga tgtattcaag attatcgcaa
     1021 tgatttaact ttttttacaa atgggcttag tgtttgttta gcagagctaa aaggatatca
     1081 ggttaccact ggcgaacctg tttgccagac ccgtcgtcta aatagtcgga tagataaagt
     1141 aagatatatg ttcaataaaa taacttagtg cgttttatgt tgttatataa atatggtttc
     1201 ttattaaata agatgaaata ttctttaata tagatttgaa ttaaagtgga aaggaggaga
     1261 ttgttattat aaactacaag tggatattgt gtcctatttg tggaaataaa acaagactac
     1321 gaatacgagt ggatactata cttaaaaatt tccctttata ctgccccaaa tgtaagaacg
     1381 aaactttaat taatgttcaa aaaatgaata taataacaat caaagagcca gacgccaaga
     1441 cgcagagccg ataatttgag aaatgaaact ctcatcttat cggctctttt tgtttatctg
     1501 aattttactg actagccttc aatatttctt gcttcattga taccttttgc tagtgcttcc
     1561 attaaggata gttctttgtc tgtaaagcta tccatgtatt tttctacctg taaccttcga
     1621 gtgcttttaa tcaaattatc tgtaggtaag aaaaattcat caatagatac atggagtaat
     1681 gatacaagat catacagcac ttgtgtactt gggtgttgtc ctttgttttc tatatttgtt
     1741 aaataacgtg ggtcaatttc aatcattgtt cccacttgtt cacgagtgag accccgtttc
     1801 attcgagcct ctttaatcgc taaaccaacg gctctaaaat cgtatttatc ttctttttta
     1861 cgcatactaa atcacctcta tacattttac tgttcctata taaccataaa caggtataga
     1921 aaaacatgtt atatagttta tgagttccta tagaacactg tggaatttat taatgcgatg
     1981 aatccaattt caaatagaaa ggtcgctgat tttatttacc tatacaactt tataaaattt
     2041 agtcatactc ctagaaagta gataaaattg gcgacttaat ggagggaaaa gtcgccatga
     2101 gaaagataat ctgtcatcta gttctcttaa ttaagttctt atcaaaaaaa cttatccacc
     2161 tgtactggat agatatgacc atcaatgtgg ttttgcagat tacatagata gaaaaatcaa
     2221 agcatatgaa cagagaaaac aatctgttta tgtgcttttt tggtcactta ataaatatct
     2281 tttaggattt ctcttcattt atgcaacaaa tcccccgttc gtgtcggggt ttagtatgaa
     2341 gggagataaa gaagcacatg ccactccctt tcacgacaga aagggggtga aaagcatgaa
     2401 accatcttct tttcaagaaa ccatagaaaa tcagtttgac tatatctgca aacaagttat
     2461 tgaagatgaa cgaaaagatt acttcaaaca tctagacaga ctatcagcaa aagaagtctc
     2521 gttttctgat atagataact accttgtcaa ctctttttct actgttgata cgtacgtcac
     2581 tgatttccaa ctatttaaat tatttggatt aagaatcaat gttgaaagtg atttattaag
     2641 tgaagccctg cgtcatcttt cagagaaaaa acggaacatt attttacttc attactttat
     2701 ggatatgagt gatgtggaga ttgcggagtt actaaatttg aatcgttcga ctgtttatcg
     2761 tcatcgaata agtggactag ccatgattaa agaattcatg aaggagtgta aagaatgaaa
     2821 acagcttatc caagggttcc cttccccctc attgtaaagg cgacagatgg cgacgtggaa
     2881 gcaattaatc agattgttaa acattatcga gggtatacct caaaacgttc attacgtcgc
     2941 atgacagacg aatatggaaa ttctcatatg gttattgatg aaaccctacg tggcagaatg
     3001 gaaacgaaac tcatctctaa gattttatcg ttcgaaatta aatagtccca ttttttcgtg
     3061 gaagcgtgtc gaatcgtatc cacgcttccc gatttgggag gtttgttatt ccatcaaagc
     3121 atattgtgtg ttcagtaggt tttgataggc taacaagcca aacgttcttt gacaaccaaa
     3181 taaaggcaat cgaatacgtt tcggtaagaa aagagctgat gaactaacac gccatgacct
     3241 acaaaattag tgagcgattc atgttagtaa ttcgaaagta atctttagca ggattgctgc
     3301 catgactttc ttatcgtgat aatgatactc ccgtatagcc atagtccgag cgttagaagc
     3361 gtcacaggca atgggtacgg ctacatgaga accatgcaga agtgaaattc ctgtgagctt
     3421 tgctagagct gttcgattgc taagatattc ttctcttgtc agtgtattat tataaaacta
     3481 tttgatataa ttataggtga atattggagt tttcctagcc tataattggg aaaggagtaa
     3541 taatgataac ggtcacaaaa aaggatttag ttgagctagg atatggaact tctttttcag
     3601 cagacatcat aaaaaaagca aaagaattga tgattacaaa agggcatatc tactatcaat
     3661 ctcgaaagct agatagagtc cctcgtgaag ctgttgaaga aattctagga attcggtttt
     3721 caaatgaaaa caggtctgag tagtttttgc acagtaagga gtaaaaacta tggttaaaga
     3781 cccaataaaa aaagcaaaga atggaaccta ttattttcgt gcaaatctag gttatgattc
     3841 taaagggaaa aaaattcaaa aatatcgtag tggattcact actaaaaaag aagcaagaga
     3901 agaatattcg aaactgctat tgatgaaacc agaagaatta agtgagaata aggataaaat
     3961 gacgtttaaa cattatatct ttgaaatttt ccttccatgg tataagacac aggtaaagct
     4021 cagaacatat gaaaatcgct taccaactat taagaagcat ttctcttatt ttgataaaat
     4081 ggctgtttcc gatattgagc ctattgatgt gcaaaattgg caactaaaat tatcaaagaa
     4141 gtgtaagtct tcttatgtaa gagctgttca aggactattt tcagttgcta tggatcgagc
     4201 aattgtcctt gggataacca ccacaaatcc atctaagatt attggcaatg tgaaaaagca
     4261 aaagtctaaa attgaatttt ggacaaaaga agaatttgaa aaagtaatct ctctaattta
     4321 caaagaagat tactatcaac actttttatt tatctctctg tggtttttat ttatgactgg
     4381 aatgcgaatt ggtgaagcta ctgccattca atgggaagat attgattttg actcaggagt
     4441 actaaccatc aacaaaacac tctattacaa gaatcaatcg aattatagat ttgttgaacc
     4501 aaaaacaaag gcgagcgttc gtcatattgt attagataaa tgcacattaa cttatttatc
     4561 cgaatggaag gaagtacaac aaaatctaat tcagacagac tttgtaatga gctataacgg
     4621 tattcctacc caaaaacata cactatcata tgctattgaa cgctatgcta agctggctgg
     4681 tatccatcga atcagaatcc atgggttacg gcattctcat gcttccttgt taatcagtat
     4741 gggagaaaat ccacttatca ttaaagatcg tctaggacac gaagatattg agacgacttt
     4801 aggaacgtat ggacatcttt atcctaacag taatttcgag gtagctaaca aattaaatgg
     4861 agccatttcc tttaaagaag caaaacaaaa ttatgatact tcaccaaaga atcaatttac
     4921 tgtagactac ttgcgaaaca aagaaatgaa aaaagtgcaa taaaagtgca gtaaaaagat
     4981 aagaagagcc agaaaccctt ggtataagag gatttctagc tctcctacaa ctattcccac
     5041 tccactgttg ctggtggttt agaagtgatg tcatacacga tacggttgac gtgggctact
     5101 tcgtttacga tacgtacaga gattttttgc aagacttccc atgggatacg ggcaaagtca
     5161 gcggtcattc cgtcgattga agttacagca cggataccga ctgtgtagtc gtaagtacgt
     5221 ccgtcaccca taacaccgac agagcggatc cctggaagaa cagtgaaata ttgccagata
     5281 tcacggtcaa gtccagcagc tgcgatttct tcacgcaaga tagcatcaga ttcgcgtacg
     5341 atttctagct tgtcttcagt gatttcgcca agaacacgaa taccaagacc aggaccaggg
     5401 aatggctgac gccaaacgat tgaatcaggc atgcctaact gagtccctaa ttcacggact
     5461 tcgtctttga ataatgtgtt taatggttcg atcaattcaa attgcatatc ttctggcagt
     5521 ccacctacat tatggtgaga tttgatcgtc tgtgctgttt ctgtaccaga ttcgataacg
     5581 tcagtataca acgttccttg tgctaggaaa gagacgcctt cttcaccagc aagttttgtt
     5641 gcttcgtcat caaaaacata tacgaattca ttcccaatga ttttacgttt ttgttctggg
     5701 tcagatacac ctttcaactt gtctaagaag cgatctcttg catcgacttt gatgatgttc
     5761 aagccgaatt ttccgcctag actttccatt acttgttccg cttcgccttt gcgtagcaga
     5821 ccgtggtcaa caaagataga tgtcaattgg tcaccgatcg ctttttgtaa aagaacccca
     5881 acgacactag aatcaacgcc acctgaaaga ccaagcaaga cttttttgtc accaacttgt
     5941 tcacggattt tttctacttg catatcgata aagttatcca ttgtccagtt accttcacag
     6001 tgacaaacat caaaggcaaa gtggcgcagc aattcgattc cgtattcgga atgacgtact
     6061 tctgcatgga attggatacc ataaaaatta cgtgttgtgt cttggataga agcaatcgga
     6121 caatctttgc ttgttccgac tgtttcaaag ccttcaggaa ctttagttac caagtcacca
     6181 tggctcatcc atactgtttg ttgttttggt gtttctttaa acaagacagc ttgatcgctt
     6241 gttacttcta acaaggcttt cccatattcg cggtttttag caggctctac ggaaccgcca
     6301 agtttgtacg tgatcaattg cataccatag caaatcccta atacaggaat acctaaattg
     6361 aagatctcag gatcgatccc aaatgcattc tcatcatata cactgtttgg tccgccagaa
     6421 agaatgattc cctttggatt catcgctttt acttcttctg cagtaatgcg gtggctcaat
     6481 aattcggaaa agactccaag atcacgaata cgtcttgtga tcaattggtt atactgacta
     6541 ccgtagtcta atacgataat cttttcaacg ttcgtcatat cggcaacgtt tgtcaaattt
     6601 attaccccta tccctttaaa ttttatctca aaatagtcaa actattttaa aatgctaata
     6661 ttttcgcatg aaaatcgaat cgatgatatg attttcagtt ttatggagaa ttatatcggc
     6721 tcttcctcgt gtaggcaaga tatattcctg taaatttttc aaattcacat ttttccatac
     6781 atcttttgcc attttaaagg cttcttcacg atctccgata gcaaaacgat aataataatt
     6841 ctctggattt tggaaagccg tatccagtaa cgcaccaaaa cgatccaaat accatttttc
     6901 gatcagcacg ggatcggcat cgacatagac agaaaaatca aaaaagtcgc tgacgtagat
     6961 ttgctgattc gcaggtaatt gaagcgtatt gatcccctca acgatcaaga tatcaggctg
     7021 ctggatcaat tcgtacttgt ctggaatgat atcatacaca tcatgtgagt aaacaggtac
     7081 ttttatctct tcctgaccag attttacacg gttcaagaaa tcgatcagca tctccatatc
     7141 ataactttca ggaaatcctt tacggtccat gattccacgc tcttttaata tacgatttgg
     7201 ataaagaaat ccgtcagtcg tgatcagctg aacgtttctt cgtttgaagg tacgagacaa
     7261 aatcgtctgc agcagtctgg ctgttgtact ttttccaacg gctacacttc cggcgatccc
     7321 gataataaaa ggcggtactt ctacgtattt atgaagaaat aaacctttac tcaagaacaa
     7381 agattcaaat tctttcatat aaagataaat cagatgagca agaggtacat agatatctcg
     7441 aacatcctgc atggaaatgc ggtcattcaa acttttgata ttatctagtt catcttgtgt
     7501 caaaggtgct tgcccattac gataaaattc tcgccattct tctcttgcca cacggtagta
     7561 gttcattgga tcattcatat tagcctcctg cgttctccca tcaatggaac tattttaaca
     7621 caaaataaac gcaaacccca ccacttaaga gagattgccg atctttttgt ataatcttta
     7681 taatagaaag aaacggagtc ttattcttga cttgcgcacg gatacataaa aggatagact
     7741 gttgtcatga aagaaatgag aaggatggaa gacatgacaa atcattacta ttctgaacgc
     7801 ccagatacgg cgcacgattt tgaacaatgg gcttttgagt taaaaggcag aacctttcaa
     7861 tttgtaacag attctggtgt attttcacgt gaaacagtgg attatggttc acgtgtcctg
     7921 attgatgctt tcgattggga agagttacct gatgaaggaa agatcttaga tgtgggatgc
     7981 gggtatggac cgattgggtt agctttggca tttgcgacac agcggtttgt tgaaatggtc
     8041 gacattaatg aacgagcggt aagtctagcg caaggaaacg caaagcgtaa ccaaatcgaa
     8101 catgttgata tccatcaatc gaatatctat gaagcagttc atgaagaaac ctatgcagct
     8161 atcgtaagca atccgccgat ccgtgctgga aaaaaagttg tacatgaaat tttgacaggc
     8221 gcatatcctc ggttgaagaa gggcggtaca ctgacaattg tgatccagaa gaaacaagga
     8281 gcgccgagtg cgcaaaagaa aatggaagaa acatttggta atgcagaaat cgtcacaaaa
     8341 gataaaggat attatatcat caaaagtgtg aaagaataac tagctgaaaa atagtggagc
     8401 gacgaaagag tggaactggg cgtgcatgta cgggtacgta tcagttcttt ttttgttgag
     8461 aagtttttaa aaacaaagaa ctattttttc ttcaaaaaga aatagtagga acagagtcgt
     8521 tgttttttac gataaaataa ataagataca gaacttgtat agaaggctgc caagtcggta
     8581 gataaaggag gtttttatca aaaaacatac tttccttttt tctctattct tttcttgggg
     8641 gttttggtac actgataggg aatttagata gaagggagcc aataggatga agctgaccat
     8701 cagagatatc gcagaaatgg caggcgtatc agtaacaact gtctcacaga ttttgaataa
     8761 caaaggaagc agatttagtg ataagacaag aaaaaaagtg ttgtcgatcg tgaatgaaca
     8821 tcattataag cccgattatt tcgcttcaaa tgtgatcaat cgacattcaa agaccatcgg
     8881 aatgatcgtc cctgatgtca ctgatttctt cttctccaaa ctgatcgaag gtgtagagag
     8941 ctatttgaat cctttgggct atgtgatcat gttatgcaat tctcgtcata gccaagaaaa
     9001 tgagatcaag tatttacaag agctttccca ccgctcagtg gacggaatct tgctggccac
     9061 accaaatatt ttacctgaga aatatgcatt agacagcggt ttttatcaaa aaatgccaat
     9121 cattttaatc gatcgcggat tgaatcgtcg ggataacgga cggcttatcg taaaggaata
     9181 tgagggcgcc tatcaagctg tttcgctgtt tattgaaaat ggccatacga agatcggcat
     9241 gctgaaggaa accactggat actatcaatt agaagaacgt ttcaacggat atcgtcatgc
     9301 gctgaaagat catggcctgc cttttaatgg gaaatttgtt gaacatggag agttgactgt
     9361 ccaaggtgga tatactgcat caaaaaaatt actcaaacat aaagatatca cggctatttt
     9421 ttgcgggaat gatgccatgg cgatcggatg ctatcaggcg atcgatgaat tgggcaaaaa
     9481 aatcccagaa gatatctcag tcataggatt cgatggatta aagctgtcag aatacatgat
     9541 tccgcaattg acgacagtgc agcagccaag ttttgatatt ggattttatg ctgcacgttt
     9601 cctgatcgat acgatcgaat ttcctcaaag aaaagttccg aacaaagtgt tcgaaacaaa
     9661 attaattatt cgtgagagcg taaaagtatt gacaaagggc taactcggcg gtatattgct
     9721 tatgtaagca tttacaaagg ctagttagtg ctttttttat ttttagtaaa ccagtttact
     9781 aaagtggttt acctttccta aaaataatgt ataataccga atgaagacaa ggaggatcag
     9841 gcaatgcgaa tggtggatct gattgaaaaa aagagggatg gaaacgagct gtcgaaagag
     9901 gaaatcgagt acatcgtcac gaactatacg aatggaaaga ttccagatta tcaagtcagt
     9961 gcattattga tggcaatttt ttatcaagac atgacaaatg aagaaatcac gaacttaaca
    10021 ttggcgattg ctaattctgg tgatgtcatc gatttgagtt ctcttgaagg aataaaggta
    10081 gataagcatt cgacaggtgg cgttggtgac acgaccacat tgattttagc ccccctagta
    10141 gctagtgtcg gagtgacagt ggctaaaatg tctggacgcg gtctaggtta cacaggtggt
    10201 acactagaca agctagaagc aattcccgga tttcagatcg agctttcgga tgaagaattt
    10261 gtacgcattg ttaatgaaag taaagtagcg gtaattggtc aatcaggaaa cttggcaccg
    10321 gcggacaaaa aattgtatgc cttgcgtgac gtcacagcga ccgttgattc tcttccgctg
    10381 attgccagtt cgattatgag taaaaaaatc gcggcaggag cagatgcaat cgttttggat
    10441 gtgaccactg gagacggtgc tttcatgaag aacatcgaag atgcaagacg tctggcaaag
    10501 accatgacga gcattgggaa actggctaac cgagaaacag tggcggttat ctcagatatg
    10561 tcagaacctc ttggcgaagc tatcggaaat agtctagaag ttgtcgaggc aatcgaaaca
    10621 ttacaaggaa atggtccaga agatctagta gaaatgtgct acgccttagg aagccaaatg
    10681 gttgttcttg ctggcaaagc taagacaacc gatgaagcaa gaacgttgct tcaagaagct
    10741 ctggaatcag gtaaagcgtt agcaaaattc aaagaaatga tccaaaatca agggggagac
    10801 ccagcgatcg tggaacatcc agaacgaatt ttgactgcac gctacacaat ggagcttcct
    10861 gctaaacaaa gcggagttgt gtcaaaaatc gtggcaaatg aattaggaat tgctgcaatg
    10921 atgctaggtg ctgggcgtaa aaccaaagaa gaagatattg atcacgctgt tggattgaaa
    10981 ctgcataaaa aaattggtga cactgtgaca aaaggtgagt cactattgac gatctatagt
    11041 aacgacgaag aaatcacttc tgtcattgaa ttattatata aaaatattga aattggtgaa
    11101 tcggcaatga agccaacgtt gattcatgac atcatcacag aataaaggaa aaaagcggac
    11161 tttaccgttt taaagaaaag gggaaaagaa atggaactaa accgaatgat cgaccatact
    11221 attttgaaag cagacgcatc taaagaagct gtgatgcaaa ttatcgaaga agcaaaaaaa
    11281 taccattttt attctgtctg catcaatcca gcatgggttg cgctagcgaa agaacaatta
    11341 caaggtgagc cagtagccgt atgtacagta atcgggtttc ctctaggagc aaacacaccc
    11401 gagacaaaag catttgaaac aacagatgcc atcaataacg gtgcagatga agtcgatatg
    11461 gtcatcaata tcggtgcttt gaaatcaaag gatgatcaac aagtccaaaa agatatcgaa
    11521 gcagttgttg aagcagcaaa agatcgtgcg cttgtcaaag ttattattga aacatcgtta
    11581 ttagatagag aagaaatcat ccgagcttgc gaaatagcaa aagctgcagg cgctgatttt
    11641 gtcaaaacat caactggttt ctcaacaggc ggagcaaagg tagaggatgt ccgtttgatg
    11701 cgtgaaactg taggaccaga aatgggtgtc aaagcttccg gcggtatcca taacgaagaa
    11761 gaagcaatgg caatgatcga agctggtgct acaagaatcg gaacaagcgc aggagtagca
    11821 atcgtatctg gttcaactgg tgaaggctat taattttttc aaaggagaag ctcatggcag
    11881 aactcaaaca agaatggatc aacacagcta ttgaagcgtt agataaagcc tatgttcctt
    11941 attcccattt tccggtaggc gcttgtctcg taacggaatc aggcaagatt tatcaaggca
    12001 tcaacattga gaatgcatca tttggattaa cgaattgtgc cgagcgcaca gcttttttca
    12061 aagcagtatc tgaaggagaa aaaacattta cgcatctagt cgtagcgggg cacacccccg
    12121 atcctatctc tccttgtggt gcatgtcgac aagtaatggc agaattctgt tcccctgata
    12181 tgccggttac gctagtagga gacaatggtg tgacgaaggc aacgaccgtt cgtgcactgc
    12241 tgccttatgc atttactgaa aaagatctat aactcatgtt cattcagtca gctgactgtt
    12301 gaaaaataaa acaattattt taggaggctt tacagaaatg aaaaaagcaa aattatttgg
    12361 tttaggtgct gtcgcactag cagcagggtt atttttaggt gcatgcggca acaacggctc
    12421 tactgattca tccggtggca aaagctcatc agacacaaca actgcagcat tgatcacaga
    12481 cacaggtggt gtagacgacc gttcattcaa ccagtcagct tgggaaggac tagaaaaatg
    12541 ggggaaagat caaggacttt cacgaggaaa tgatggcttc caatatttcc aatcttcaaa
    12601 tgaatcagat tacatcccaa atattgacca agcattgaat gctggattca aaacgatttt
    12661 tggtattggt tataaactaa aaccagcgat ccaagaacaa gcaacaaaca atacaggtac
    12721 gaactttgtt attatcgatg atgtcatcga tggattagat aacgttgtat ctgcaacttt
    12781 caaagacaac gaagcttctt atcttgcagg tgttgcagca gcttatacga ctgaaacaaa
    12841 cgtagtcggc tttatcggcg gtgtaaaagg tgaagtaatc gatcgttttg atgctggatt
    12901 caaagccggt gttgatgcag gtgcgaaaga attaggaaaa gaaatcaaag tattgaatca
    12961 atatgctggt gacttctctg ctccagataa aggacgttca attgctcaag gtatgtatgc
    13021 acaaaacgca gatatcatct tccatgcttc aggcggtaca ggtaacggtg tattccaaga
    13081 agcaaaatca ttgaacgaat caggcgacaa aaaagtttgg gttatcggtg ttgaccgcga
    13141 ccaatcagac gaaggcgaat acacattaaa cggcgaaaag aaaaacttca cattgacatc
    13201 tacactgaaa gcagttggaa cagtagtaga agatttggca caaaaatcag cggacggtaa
    13261 attccctggc ggcgaacaca ctgtttatgg attgaaagaa gacggtgttg gtctaacaga
    13321 aggacaactt tctgacgaag cgaaaaaagc agttgatgaa gcaaaagaaa aaatcatttc
    13381 aggtgacgta aaagttccag aaactcctga agaaaactaa aaccatttct atagccttgt
    13441 tagacacatg tttgacaagg ctatggtttg attagaacaa gaattgttca tttatccaag
    13501 ctgccttgtg acagtttgga taagggaaca actccctgaa gtaatgtttg tttcaaaaga
    13561 agaacgctca ctaagcgtga atcttagtca atcgttgccc tagatagaaa tcgttaggat
    13621 gtgaaaaaaa ggtggttcaa gaaaatattg tcatagaaat gcagaatatt accaaagaat
    13681 ttggaacatt caaggcaaat gacaacatca atttacaagt aaaggcagga gaaattcatg
    13741 cgttgcttgg agaaaacggt gctggcaaat ctacattgat gaacgtgctt tccggattat
    13801 tagagccgac atcagggaaa attttgatgc gtgggaaaga agtaaagatc acaagtccga
    13861 ccaaagccaa ccaattaggg attgggatgg tccatcagca ctttatgctt gttgatgcct
    13921 ttactgtaac agaaaacatc gtgttgggaa gcgagcctag tcgcgcaggg atgcttgacc
    13981 ataaaaaagc acgaaaagag atccaaaaag tttctgaaca gtatggattg tcagtcaacc
    14041 cagatgctta cgttcgtgat atttcagttg gaatggaaca acgggtagaa attttaaaaa
    14101 cactttaccg aggagcagat gtactgattt ttgatgagcc gacagctgta ttgacccctc
    14161 aagaaattga tgaattaatc gtgatcatga aggaattagt caaagaaggc aagtcgatca
    14221 ttttgattac gcataagtta gatgaaatca aagcagtagc tgaccgctgt acagttatcc
    14281 gccgtggaaa aggaatcggt acagtcaacg ttaaagacgt aacctcacaa caattagccg
    14341 atatgatggt tggaagaacg gtttcattca aaacgatgaa aaaagaagcg aagcctcaag
    14401 aagtcgtttt gtctattgaa aatctagtgg tgaaagaaaa tcgtggatta gaagccgtga
    14461 aaaacttgaa cttagaggtt cgtgctggcg aagtacttgg tatcgctgga atcgatggaa
    14521 acgggcagtc ggagttgatc caagctttga ctggtttgcg aaaggcagaa agcggacata
    14581 tcaagctaaa aggggaagac atcactaata aaaaaccccg aaaaatcact gaacatggtg
    14641 taggacacgt gccagaagac cgtcataaat acgggttagt cctagatatg acattatctg
    14701 aaaatatcgc actacaaacc tatcatcaaa aaccttacag taaaaacggc atgctgaatt
    14761 attcagtaat gaatgaacat gccagagaat tgatcgaaga atatgatgtt cgaacaacga
    14821 atgaacttgt tcccgcaaaa gctttatcag gcggaaatca gcaaaaagca attatcgctc
    14881 gtgaagtcga ccgagatcct gatctgttga ttgttgcaaa tccaactcgt ggactggatg
    14941 taggtgcgat cgaatttatt cataaacgtc tgatcgaaca aagggacaaa tacaaagcag
    15001 tgttactgat cagtttcgaa ttagaagaaa ttttaaatgt ttcggatcgt attgctgtta
    15061 tccatgaagg agaaattgtc ggtatcgttg atccgaaaga aacatctgaa aatgaattag
    15121 gtctattgat ggcgggctat accttagaag aagcacgaaa agagttagaa aagggggctg
    15181 gcgcacatga atgatcgcag cgaaaaattc cgtaatttat tagtgcctgt actttcagtt
    15241 gttttaggat tgatcttagg cgcgatattg atggctgctt ttggttttca gcccatccaa
    15301 ggttattctt ctatgctaga tgcagccctt ggttcgcaaa gagggatagg tgaaacgtta
    15361 aggcaagcaa cgccgttgat ttttacagca ttaggttttt ctgtagctaa ctcagctggg
    15421 tttttcaata ttgggctttc tggacaagca ctttgcgggt ggatcgtcag tgtctgggtg
    15481 gcacttgcgt ttccagatct gccaaaagtt gttttgcttc cgttatgcgt gatcttaggt
    15541 gccttagctg gtgcgatggc agcggctgtt ccaggtttac ttcgagcatt ttttggaaca
    15601 agtgaagtga tcgtaacaat catgatgaac tatatcttat tatacgtaag cacatttgct
    15661 ttacatgaag tgatgcctga aagctatcgc tcaagtttgg actcttccaa tatgatcagt
    15721 caaaatgcct cactgcggtt accatggtta acacaagctt ttggcggctc tcgcgtaaac
    15781 tcaggattat ttttagcaat catcgcgctt attttcgttt ggctgctgat gaagaaaacg
    15841 actttaggat ttgaaatccg ttctgttgga ttgaatcctt ttgcttctga gtatgcagga
    15901 atgagtagta aacgtacgat cgttttgtcg atggtcattt ctggcgcttt ggcagggctt
    15961 ggcggtgtgg ttgaaggatt aggaacgtat caaaacttct ttgttcaaac gacttcgcta
    16021 tctattggat ttgacggaat ggctgtttcc ttgcttggtt ctggatcagc aatcggtatt
    16081 cttttatcag cgatcttgtt cagtattttg aagatcggtg gacttggcat gcagacagga
    16141 gcaggtgttc cgtttgagat cgtcaatgta tcgattgctt tgattatctt ctttgtcggg
    16201 atcaacttcc tgattcgttt cgtcatggct aaagtcttcc aagggaaaaa acaagaagag
    16261 atcgttgcga caatagaatc gaaaccaacg aatcaaaacc atgaaggggg cgaactataa
    16321 tgtcgactat cgaattaatt gccttgatcc ttacttctac actggtttat tcaacaccgc
    16381 taattctaac gtcactaggc ggaacttttt ctgaacgaag cgggatcgta aacgtagggc
    16441 tagagggaat catggtcatg ggtgctttta gttccatcgt tttcaacttg acgatgagtc
    16501 catcacttgg ttctatgaca ccatggatcg ctattttagt gggtggcgtc gtaggtatcc
    16561 tattttctct gattcacgca gtagcaacag tcagtttgcg tgctgaccat attatcagcg
    16621 ggacagtaat taatctgatg gcacctgctt taggtgtttt cttgatcaaa gcatggtatg
    16681 gtaaaggtca aactgataac atcacgcaga atctggggta tttttctttc ccaggattag
    16741 cagatattcc ggtcattgga ccaattttct ttaaaaatac attcttacct gcttattgtg
    16801 ctattttgat tgctgtccta gcttgggtga tcatcttcaa gacgaaattc ggcttgcgcc
    16861 tccgttcagt tggtgaaaat cctcaagctg ccgacacatt aggtatcaat gtatatgcta
    16921 tgcgttattc aggcgtactg atttctggct tgttaggcgg tatgggcggt gctgtttttg
    16981 ctcagtcgat ttccggtaac ttttcagctg gtacgatcgt tggacaaggg ttcatctcca
    17041 tggctgctat gatctttggt aagtggaatc ctttaggggc aatgggtgcc tcattgttct
    17101 ttggttttgc tcaaagcttg agtatcattg gcgcacaatt accagttatt tcttcgattc
    17161 cgccagtatt gctgcaaatt gctccatatt tgctgacaat cattgtgctg gttgttttct
    17221 tagggaaagc ttctggtcca aaagcaaacg ggaagaacta tatcaaatca aaataatctt
    17281 ttagcgaata aaaagggtgg gttacgggaa gtgtttttcg tctcgccctt tttgttttaa
    17341 aggcaataaa aataaaaaga aagaaggaat aatcatgttt aaacgcgtac atctgatcgt
    17401 catggattca gtaggaattg gagaagcacc agatgccgat aagttcggtg atgttggttc
    17461 tgatacatta ggacacattg cgaaagaagc aggattgaac gttccacatt tagagcagct
    17521 tggtttagga acgatccgtc ctcttgaagg tgtggaatca gtgaaagatc atcaaggcta
    17581 tgcgacgaaa ttagaagaag tttctgtagg gaaagatacg atgacaggcc actgggaaat
    17641 catgggattg aatatcaaaa ctccatttcg tgtgtttcct aatggattcc ctgatgatct
    17701 gatcaaacaa atcgaagaat tttctggccg taaagtcgta tgtaacaaac cttatagcgg
    17761 aacagctgtt attgacgatt acggtgaaca ccaaatgaaa acaggcgatt taattgtata
    17821 tacttctgcc gatcctgtcc ttcagatcgc ggcacatgaa gaaatcattc ctttagaaga
    17881 attatatcgg atttgccaat tcgttcgtga tataacaaaa gatgatccgt atatgattgg
    17941 ccgaatcatt gcacgtccgt acgtgggtga accaggagac ttcacacgaa caagcaatcg
    18001 ccatgattat gcgttgaatc cattcggaca cacagtcctt gattctttga aagaagcagg
    18061 aaaggacgtg attgctgttg gaaagatcaa cgatattttc aacggacaag gaatcactga
    18121 atctgtccgc acgaaaagca atatggatgg cgttgaccag ctgctgaaag ttatgaaaaa
    18181 cgatttttca ggaatcagct ttaccaattt agtagatttt gatgcattat acggtcatcg
    18241 tcgggatgta gtcggctatg cgcatgcgat tgaagaattt gacttacgaa ttccagaatt
    18301 gcttgaagcg atggaagaag acgacttgct aatgattaca gccgatcacg gaaacgatcc
    18361 gacgtttact ggtaccgatc atacgcgaga atatgtaccg ttattggttt acagtaaaaa
    18421 aatgaaagaa caaggggcat tgcctcaagg atattattca gatatttcag caacgattgc
    18481 tgagaacttt agtgtttctt cgactgaaaa tggcgaaagc ttcttgaaat tattaaaata
    18541 atctttttaa ataggagaaa gcaaatgacc aagttaagcg agatgttaca agaaacgacc
    18601 cagtttatcc ttgataaagg agtaaaagaa attgattttg gtttgattct aggttcagga
    18661 ttaggtgaat tagcagatga aatcgaagat gctgtaatga tttcttatga tgagatcccg
    18721 ttctttcctg tttcgacagt agttgggcat gcaggaaagc tagtttatgg gtctctggca
    18781 ggcaagaaag tgttagccat gcaagggaga ttccactact atgaaggtca ttccatgcaa
    18841 acagtgacct atccagtacg tgtgatggcc ggactagggg cccattcagt cattgtgact
    18901 aatgcatgtg gtggtgtcaa cgaatcattt gtaccaggag atttgatgct gattaccgat
    18961 catatcaatt ttactggtga aaatcctttg atcggtccga atgaagatgc aatgggccct
    19021 agatttccag atatgagtca agcttatacg cctgactatc aagcaacagc aaaagcagca
    19081 gcagaaaaac taggtttgga tcttaaagaa ggcgtatata tgggctattc tggaccaact
    19141 tatgaaacgc ctgcggagat ccgaatgtct cggacaatag gagccgatgc agtagggatg
    19201 tcgactgttc cagaagtcat cgtagcagct cacagcggat taaaagtgtt aggaatctct
    19261 tgtattacca acttagcagc aggtatgcaa gcgaatctga gccatgaaga agttgtagaa
    19321 acaactcaga gagtcaaaca atcttttaaa gcattggtta aagaaacatt gacattattg
    19381 taataggagg aacaataaaa tgagtgtgca tattgaagcg aaagaaggcg agatcgccga
    19441 taagatttta cttccgggag atcctttgcg agctaaatat attgcggaga cttttttgga
    19501 agatccagtt tgttacaatc aggtacgcgg tatgttaggc tttaccggca aatataaagg
    19561 agaacgtatt tctgttcaag gaacaggaat gggaatgcca tcagccacca tctatgccca
    19621 tgaattgatc cagtcgtatg gtgtaaagaa attgattcga gtaggtacat gcggtgcatt
    19681 gtcaaaagac gtccatgttc gtgatttagt actagcacaa ggtgcagcga ccagttcttc
    19741 gatgatcgaa aaaaatttcc aagcctttca ttttcctcca atcagtgatt tcaatctatt
    19801 actgaaagca tatgagatag ctaaagaaaa gggctatacg gttcatgtag gaaatgttct
    19861 ttcggaagat tctttctaca aagatgattt gacagagacg ttccaattag ctgaacttgg
    19921 cgttttagga gtggaaatgg aagcagcggc tctttattac ttaggcgcga aataccatgt
    19981 gcagacatta agtttgatga ccgttagcga ccatttgatc accggtgaag aaacaacagc
    20041 tgcagaacgt caatctacgt tcaatgaaat gatcgaagta ggattggaaa cagcgatagc
    20101 agaataagaa ggaaatgaaa aagctgccct gcattaagta ataagaacat ccaagcaaaa
    20161 atagctcctc atgtttttga cttggctgga cttattattg caaatgtaag cttttgaaca
    20221 ccgtttacca agaggttgtg aatctgccgt ttaactctga gtcacaagga acaatttcaa
    20281 aaa
//
LOCUS       DBGZHO010000194         7959 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.098, whole genome shotgun sequence.
ACCESSION   DBGZHO010000194 DBGZHO010000000
VERSION     DBGZHO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.098"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            128..1564
                     /locus_tag="ACN3HL_002976"
     CDS             128..1564
                     /locus_tag="ACN3HL_002976"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HHC8007743.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="ACN3HL_002977"
     CDS             1753..4200
                     /locus_tag="ACN3HL_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HHC8007744.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="ACN3HL_002978"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="ACN3HL_002978"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HHC8007745.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            5487..5693
                     /locus_tag="ACN3HL_002979"
     CDS             5487..5693
                     /locus_tag="ACN3HL_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007746.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(5690..6793)
                     /locus_tag="ACN3HL_002980"
     CDS             complement(5690..6793)
                     /locus_tag="ACN3HL_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HHC8007747.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACN3HL_002981"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACN3HL_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HHC8007748.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DBGZHO010000195         7478 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.102, whole genome shotgun sequence.
ACCESSION   DBGZHO010000195 DBGZHO010000000
VERSION     DBGZHO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.102"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            109..192
                     /locus_tag="ACN3HL_002982"
     CDS             109..192
                     /locus_tag="ACN3HL_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HHC8007749.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            317..1054
                     /gene="erm(B)"
                     /locus_tag="ACN3HL_002983"
     CDS             317..1054
                     /gene="erm(B)"
                     /locus_tag="ACN3HL_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HHC8007750.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1224..1484
                     /locus_tag="ACN3HL_002984"
                     /pseudo
     CDS             1224..1484
                     /locus_tag="ACN3HL_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1647..2312
                     /locus_tag="ACN3HL_002985"
                     /pseudo
     CDS             1647..2312
                     /locus_tag="ACN3HL_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2348..2593
                     /locus_tag="ACN3HL_002986"
     CDS             2348..2593
                     /locus_tag="ACN3HL_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HHC8007751.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2696..3565
                     /locus_tag="ACN3HL_002987"
     CDS             2696..3565
                     /locus_tag="ACN3HL_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HHC8007752.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3546..4280
                     /locus_tag="ACN3HL_002988"
     CDS             3546..4280
                     /locus_tag="ACN3HL_002988"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HHC8007753.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4313..5221
                     /locus_tag="ACN3HL_002989"
     CDS             4313..5221
                     /locus_tag="ACN3HL_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HHC8007754.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5218..5760
                     /gene="sat4"
                     /locus_tag="ACN3HL_002990"
     CDS             5218..5760
                     /gene="sat4"
                     /locus_tag="ACN3HL_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HHC8007755.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5853..6647
                     /locus_tag="ACN3HL_002991"
                     /note="aph(3')-IIIa"
     CDS             5853..6647
                     /locus_tag="ACN3HL_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HHC8007756.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6923..7465
                     /locus_tag="ACN3HL_002992"
     CDS             6923..7465
                     /locus_tag="ACN3HL_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HHC8007757.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         2622 a         1129 c         1566 g         2161 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccatt ttgtgtataa taggaattga
       61 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
      121 caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa cagtgattac
      181 gcagataaat aaatacgtta gattaattcc taccagtgac taatcttatg actttttaaa
      241 cagataacta aaattacaaa caaatcgttt aacttctgta tttatttaca gatgtaataa
      301 cttcaggagt gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga
      361 aaaagtactc aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga
      421 aattggaaca ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac
      481 gtctattgaa ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat
      541 tcgtgtcact ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta
      601 taaaattgtt gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt
      661 tgaaagccat gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt
      721 ggatattcac cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct
      781 taagctgcca gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact
      841 tacccgccat accacagatg ttccagataa atattggaag ctatatacgt actttgtttc
      901 aaaatgggtc aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat
      961 gaaacacgcc aaagtaaaca atttaagtac cgttacttat gagcaagtat tgtctatttt
     1021 taatagttat ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg
     1081 gaaagttaca cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt
     1141 ccaagaagct aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa
     1201 ttcccactaa gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg
     1261 tattaaaaaa atcgttttat ggttgttcaa attatcctga atgtaagttt actttagctg
     1321 aacattttag aaagaaaaaa ctaaccaaaa cgaatgtaaa agaattactg gagggaaaag
     1381 aaaccctggt aaaaggaatc aaaaacaaag agaaaaagcc ctacaatgcc gttgtaaaaa
     1441 ttggggaaaa gggatatatt gattttatct ctttttcaaa ataaacatgg ggctgaccca
     1501 aaagtagctc ctatatgaaa aatagaggtc tttccattta gatagtagtg gaaagacctc
     1561 tatttatctt ttgaaagtga atacaaaaat aaagcacact ctgctataat ataggtgatt
     1621 aatccatttg agagaggtgc tttatcatgt atcaaaatta taccataaac caactttgtt
     1681 tgcctataga tcttgaaatt aaattagaag aaaatgattt tgctcatgcc attgtgcagt
     1741 ttgttgactc tattcccgat gaagtctttc ttccttatta tcaatctatg ggtagacccc
     1801 aatatcatcc tcgtatgcta ctttccatta ttctttgtgc ctatattcaa ggggtttatt
     1861 cgggccgcca aatacaaaat atgctgatag atagtattcg gatgcgctac ttatctcaag
     1921 agcaattccc taactttcgt actattaatc gttttcgcgt tcatccgatt atgaacgata
     1981 ttctagatca ttcatttgtt caatttcgtg agctactggt tcaaagtggc ttaatcagtg
     2041 gcagtgctct atacattgat ggtacaaaaa ttgaagcgga tgcgaataaa tactctttcg
     2101 tttggaaaaa aagtatttta aagtataagg atagccttga tcaaaaagcc cttgaaaact
     2161 accaacaaat ggtggaaaca aaaatcttac ctgagttaat agatgattta aaggatgaac
     2221 tttctataga agagattgaa aggattcgtc aatctttgga agaaaaggaa aatcaattaa
     2281 ttgaagcgat tgaccaaacc gaaacagtag aagggggctg acccattatt aataaggagt
     2341 ggacaacatg attgatgtaa atgagctatt ggaagaagct attagagaaa ctgaaaatct
     2401 aaatgatggc gaagtttttc ttgttaaaga tttattcaag ggatatgtgg ggaataggat
     2461 acccagaaag gatcgacttc tgcttggaac gttattttta aaccatgtta gcaaaatgaa
     2521 tggtaattta aaggctattg aaaagacttc atctaatcag cagaggtata aaaagacaat
     2581 tgataagttt taactatctt ttgtgaaatt aaaaaaatta taaatatgtt gagtagaagc
     2641 aaaagatttg gcttggaatt tttacagcag tgaatcgata aaaggagcat gcttgatggt
     2701 agataatatt attaaatcag tagcagagaa attatcctct ctgtcttata tagaaggtat
     2761 tgttttaggt ggttcacgtg caaggggcac ccatacagag gattcggata tagatatcgg
     2821 catctattac aattcagaat catttgacat aaatactatt aatcaattcg ctacaaagct
     2881 ggatgatgag catagaaata accttgttgt acctcccgga gcatggggtg attggattaa
     2941 tggcggcgga tggttagtca taaacgggta tcatgtggat ttaattttac gtgatattaa
     3001 acgtgtggaa caaataatga aagatacaga gcacggaatt gttactgcca attatcagac
     3061 tgggcatccc catggttata ttagtgcaat gtatcgagga gaattagcga ttagcaaaat
     3121 actatatgct aagaatgaaa gcttatgcga attaaaaaaa caggcagaaa cttatcccaa
     3181 tgctttgcag aaaagtttag ttaacttttt tatgtttgaa gcagggttct ctttaatgtt
     3241 tgtaaaagca aattcgggaa cagacgataa atattatatt gcgggtcatg tttttcgtat
     3301 agtttcatgt ttaaatcaag tgttatttgc atgtaataat gcttattgta tcaacgaaaa
     3361 gaaagctata aaactgcttg aaacttttga acataaacct gaaaaatata ccgagaaggt
     3421 aaatcatatt tttgaagtac tcggtatctc actttttgaa tgctacgaca tgaccgagaa
     3481 gctttataat gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag
     3541 ttcagatgaa agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga
     3601 gtcgctcgca gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac
     3661 ctgattttaa gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat
     3721 atgcgatgga aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg
     3781 aagtagcaaa aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag
     3841 atgtggattt cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg
     3901 tagcagacta tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt
     3961 tagtttttac agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata
     4021 acgaaaaagg agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga
     4081 cagctatgtt tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa
     4141 atacactgct ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga
     4201 acatgatgga tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat
     4261 cggcaaaaaa gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc
     4321 agaaaaagaa atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat
     4381 tgtgaccctt gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta
     4441 tgatattaca tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa
     4501 tcaatttggg aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga
     4561 agaaaaggga ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt
     4621 attgcccttg gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat
     4681 tgataaagat tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag
     4741 aaagccaagc gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta
     4801 tgttattaaa ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat
     4861 tgttcgccat gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa
     4921 attaagtgta ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga
     4981 gaaacttttg tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct
     5041 atgccatcaa ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta
     5101 tccggagtat gataggaata taacaaaata taccagggac atgtataaaa aatacactgg
     5161 taaaaccggc tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg
     5221 attacagaaa tgaaagcagg gcacctgaaa gatatcgata aacccagcga accatttgag
     5281 gtgataggta agattatacc gaggtatgaa aacgagaatt ggacctttac agaattactc
     5341 tatgaagcgc catatttaaa aagctaccaa gacgaagagg atgaagagga tgaggaggca
     5401 gattgccttg aatatattga caatactgat aagataatat atctttacta ccaagacgat
     5461 aaatgcgtcg gaaaagttaa actgcgaaaa aattggaacc ggtacgctta tatagaagat
     5521 atcgccgtat gtaaggattt cagggggcaa ggcataggca gcgcgcttat caatatatct
     5581 atagaatggg caaagcataa aaacttgcat ggactaatgc ttgaaaccca ggacaataac
     5641 cttatagctt gtaaattcta tcataattgt ggtttcaaaa tcggctccgt cgatactatg
     5701 ttatacgcca actttgaaaa caactttgaa aaagctgttt tctggtattt aaggttttag
     5761 aatgcaagga acagtgaatt ggagttcgtc ttgttataat tagcttcttg gggtatcttt
     5821 aaatactgta gaaaagagga aggaaataat aaatggctaa aatgagaata tcaccggaat
     5881 tgaaaaaact gatcgaaaaa taccgctgcg taaaagatac ggaaggaatg tctcctgcta
     5941 aggtatataa gctggtggga gaaaatgaaa acctatattt aaaaatgacg gacagccggt
     6001 ataaagggac cacctatgat gtggaacggg aaaaggacat gatgctatgg ctggaaggaa
     6061 agctgcctgt tccaaaggtc ctgcactttg aacggcatga tggctggagc aatctgctca
     6121 tgagtgaggc cgatggcgtc ctttgctcgg aagagtatga agatgaacaa agccctgaaa
     6181 agattatcga gctgtatgcg gagtgcatca ggctctttca ctccatcgac atatcggatt
     6241 gtccctatac gaatagctta gacagccgat tagccgaatt ggattactta ctgaataacg
     6301 atctggccga tgtggattgc gaaaactggg aagaagacac tccatttaaa gatccgcgcg
     6361 agctgtatga ttttttaaag acggaaaagc ccgaagagga acttgtcttt tcccacggcg
     6421 acctgggaga cagcaacatc tttgtgaaag atggcaaagt aagtggcttt attgatcttg
     6481 ggagaagcgg cagggcggac aagtggtatg acattgcctt ctgcgtccgg tcgatcaggg
     6541 aggatatcgg ggaagaacag tatgtcgagc tattttttga cttactgggg atcaagcctg
     6601 attgggagaa aataaaatat tatattttac tggatgaatt gttttagtac ctagatttag
     6661 atgtctaaaa agctttaact acaagctttt tagacatcta atcttttctg aagtacatcc
     6721 gcaactgtcc atactctgat gttttatatc ttttctaaaa gttcgctaga tagagttcta
     6781 tattagagat gtaaagagtt ttggtgaaga ggtttgtgag tatggctttt ataaccaggg
     6841 tgcaatgaga agcactaaca gcagctagct taagaacgca taggatatac tttttatgga
     6901 agtcacagag gaggaataaa atttgaacag gattaacaga gtaacctcta ttcttattca
     6961 gctgcaatca aaaaaaataa ttcctgccaa agaaattgca cagcgattta atataagctt
     7021 aaggacagtt tacagagata tccggacact tgaagaagcc ggaataccaa ttggatctga
     7081 ggccggaaaa ggatattttc ttgtagaggg cttcctactt ccgccggtaa tgtttacagc
     7141 ggcggaagtg ggtgcattga ttacagcagg gaaattttta aattgccatg gagatgaatc
     7201 atttataaag gattttgatt cagctatgta taaaatcaaa tctattttga agcatggtga
     7261 aaaaaactat gcacaggagt tggagaacag tattaacgtg tacagcacat ctggacagaa
     7321 aaatacattg gcggataacg ttattgcagc aattcagact gcaatctgca ataaaagggt
     7381 aatatcaatt caatatcctg catcaggagg gcaagaaccg gaaagcagaa tgatagagcc
     7441 ggttctgttg caaagtttta aataaagaat aaaatccc
//
LOCUS       DBGZHO010000196         5586 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.107, whole genome shotgun sequence.
ACCESSION   DBGZHO010000196 DBGZHO010000000
VERSION     DBGZHO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.107"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            246..1214
                     /locus_tag="ACN3HL_002993"
     CDS             246..1214
                     /locus_tag="ACN3HL_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HHC8007758.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1207..2238
                     /gene="vanA"
                     /locus_tag="ACN3HL_002994"
     CDS             1207..2238
                     /gene="vanA"
                     /locus_tag="ACN3HL_002994"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HHC8007759.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2244..2852
                     /locus_tag="ACN3HL_002995"
     CDS             2244..2852
                     /locus_tag="ACN3HL_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HHC8007760.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3280..4191
                     /gene="vanY"
                     /locus_tag="ACN3HL_002996"
     CDS             3280..4191
                     /gene="vanY"
                     /locus_tag="ACN3HL_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HHC8007761.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4344..4829
                     /gene="vanZ-A"
                     /locus_tag="ACN3HL_002997"
     CDS             4344..4829
                     /gene="vanZ-A"
                     /locus_tag="ACN3HL_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HHC8007762.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5116..5445)
                     /locus_tag="ACN3HL_002998"
     CDS             complement(5116..5445)
                     /locus_tag="ACN3HL_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HHC8007763.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
BASE COUNT         1781 a          966 c         1200 g         1639 t
ORIGIN      
        1 gatgctggtg tcatccacca acatcaaaaa gtatagagcc ataatttttt aggaaaatct
       61 caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa acggctcgtt
      121 cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag agaaagattt
      181 gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa gggttggtct
      241 taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag gcagatgcat
      301 tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg
      361 aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat aaatcagaga
      421 tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt tctacccgaa
      481 gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc actgtcgaca
      541 atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt cttatggcag
      601 tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg
      661 accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc cagataggca
      721 aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat agtcgcagcc
      781 gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc gatatcgtta
      841 cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa caaatacaga
      901 gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta gatacctatg
      961 agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat gtattggaag
     1021 gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat caatttttac
     1081 ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat tataccgagc
     1141 aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt gaaaggagac
     1201 aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga ggagcatgac
     1261 gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa atacgagccg
     1321 ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa
     1381 tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat gcacggatta
     1441 cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt ttcagctttg
     1501 catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc cggtatccct
     1561 tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt gacatacatc
     1621 gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa agatgatagg
     1681 ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc
     1741 ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga atcggcaaga
     1801 caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg
     1861 gtattgggaa acagtgccgc gttagctgtt ggcgaggtgg accaaatcag gctgcagtac
     1921 ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata
     1981 accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa
     2041 atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt acaagataac
     2101 ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata cagtcgttat
     2161 ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg cttgatcgta
     2221 ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat gaaatagtac
     2281 acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga aaaccggttg
     2341 acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg cttttgaagg
     2401 caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt taccgtccta
     2461 atcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg
     2521 aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac gtggcttcaa
     2581 aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta gacacgggtg
     2641 agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat catgcggcaa
     2701 atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca
     2761 gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac gaaccatacc
     2821 ccaatagcta ttttgatttc cccgttaaat aaacttttaa ccgttgcacg gacaaactat
     2881 ataagctaac tctttcggca ggaaacccga cgtatgtaac tggttcttag ggaatttata
     2941 tatagtagat agtattgaag atgtaaggca gagcgatatt gcggtcatta tctgcgtgcg
     3001 ctgcggcaag atagcctgat aataagactg atcgcataga ggggtggtat ttcacaccgc
     3061 ccattgtcaa caggcagttc agcctcgtta aattcagcat gggtatcact tatgaaaatt
     3121 catctacatt ggtgataata gtaaatccag tagggcgaaa taattgactg taatttacgg
     3181 ggcaaaacgg cacaatctca aacgagattg tgccgtttaa ggggaagatt ctagaaatat
     3241 ttcatacttc caactatata gttaaggagg agactgaaaa tgaagaagtt gtttttttta
     3301 ttgttattgt tattcttaat atacttaggt tatgactacg ttaatgaagc actgttttct
     3361 caggaaaaag tcgaatttca aaattatgat caaaatccca aagaacattt agaaaatagt
     3421 gggacttctg aaaataccca agagaaaaca attacagaag aacaggttta tcaaggaaat
     3481 ctgctattaa tcaatagtaa atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg
     3541 aatttatcta aacatgacga attaataaat ggatacgggt tgcttgatag taatatttat
     3601 atgtcaaaag aaatagcaca aaaattttca gagatggtca atgatgctgt aaagggtggc
     3661 gttagtcatt ttattattaa tagtggctat cgagactttg atgagcaaag tgtgctttac
     3721 caagaaatgg gggctgagta tgccttacca gcaggttata gtgagcataa ttcaggttta
     3781 tcactagatg taggatcaag cttgacgaaa atggaacgag cccctgaagg aaagtggata
     3841 gaagaaaatg cttggaaata cgggttcatt ttacgttatc cagaggacaa aacagagtta
     3901 acaggaattc aatatgaact atggcatatt cgctatgttg gtttaccaca tagtgcgatt
     3961 atgaaagaaa agaatttcgt tctcgaggaa tatatggatt acctaaaaga agaaaaaacc
     4021 atttctgtta gtgtaaatgg ggaaaaatat gagatctttt attatcctgt tactaaaaat
     4081 accaccattc atgtgccgac taatcttcgt tatgagatat caggaaacaa tatagacggt
     4141 gtaattgtga cagtgtttcc cggatcaaca catactaatt caaggaggta aggatggcgg
     4201 aatgaaacca acgaaattaa tgaacagcat tattgtacta gcacttttgg ggtaacgtta
     4261 gctttttaat ttaaaaccca cgttaactag gacattgcta tactaatgat acaacttaaa
     4321 caaaagaatt agaggaaatt atattgggaa aaatattatc tagaggattg ctagctttat
     4381 atttagtgac actaatctgg ttagtgttat tcaaattaca atacaatatt ttatcagtat
     4441 ttaattatca tcaaagaagt cttaacttga ctccatttac tgctactggg aatttcagag
     4501 agatgataga taatgttata atctttattc catttggctt gcttttgaat gtcaatttta
     4561 aagaaatcgg atttttacct aagtttgctt ttgtactggt tttaagtctt acttttgaaa
     4621 taattcaatt tatcttcgct attggagcga cagacataac agatgtaatt acaaatactg
     4681 ttggaggctt tcttggactg aaattatatg gtttaagcaa taagcatatg aatcaaaaaa
     4741 aattagacag agttattatt tttgtaggta tacttttgct cgtattattg ctcgtttacc
     4801 gtacccattt aagaataaat tacgtgtaag atgtctaaat caagcaatct gatctttcat
     4861 acacataaag atattgaatg aattggatta gatggaaaac gggatgtggg gaaactcgcc
     4921 cgtaggtgtg aagtgagggg aaaaccggtg ataaagtaaa aagcttacct aacactatag
     4981 taacaaagaa agcccaatta tcaattttag tgctgaggaa ttggtctctt taataaattt
     5041 ccttaacgtt gtaaatccgc attttcctga cggtaccccc aaactaagat ttcatagata
     5101 gattttctga taactttaaa aaacacgaat agcggaaagg atgtcttcat tcgctaaaga
     5161 gtaataaact acttttccat cttgacgtga ttttgccatt ccatgttttt ttaaaaaacg
     5221 taaatggtgt gacgttgtag cgacactagc agtaagtatt tctgctaaat cacagacgca
     5281 catttcctta taggtttcta aagcatagaa aattttaatt ctagaaaaat cgctgaaaca
     5341 tttccctaac acaagtaagt ttgaaaaatc tttttgatcc aatttatttt ttattccatt
     5401 tactttttct ttatgtacga cagtcacttg gcaaactttt ttcattcatc tcacctcaca
     5461 ttcaaacgat tatttgaatg aagtatacct atttgatcac tcttttgtca atctacctta
     5521 attccaatac actattataa gcaatttggt tctgttgcaa agttttaaat aaagaataaa
     5581 atccct
//
LOCUS       DBGZHO010000197         3970 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.126, whole genome shotgun sequence.
ACCESSION   DBGZHO010000197 DBGZHO010000000
VERSION     DBGZHO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.126"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACN3HL_002999"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACN3HL_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HHC8007764.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACN3HL_003000"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="ACN3HL_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HHC8007765.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1255 a          613 c          817 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaagaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata atgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DBGZHO010000198         3095 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.131, whole genome shotgun sequence.
ACCESSION   DBGZHO010000198 DBGZHO010000000
VERSION     DBGZHO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.131"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            93..590
                     /gene="dfrG"
                     /locus_tag="ACN3HL_003001"
     CDS             93..590
                     /gene="dfrG"
                     /locus_tag="ACN3HL_003001"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HHC8007766.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(662..2614)
                     /locus_tag="ACN3HL_003002"
     CDS             complement(662..2614)
                     /locus_tag="ACN3HL_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HHC8007767.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2621..2857)
                     /locus_tag="ACN3HL_003003"
     CDS             complement(2621..2857)
                     /locus_tag="ACN3HL_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007768.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          940 a          550 c          514 g         1091 t
ORIGIN      
        1 cttattcaac taacgggcag gataatgaga aaaggttttt tgatagaaat aagaaattag
       61 atggtaaatt agttaaaaag gctgtgttat aaatgaaagt ttctttgatt gctgcgatgg
      121 ataagaatag agtgattggc aaagagaatg acattccttg gaggattccc aaggactggg
      181 aatatgttaa aaatactaca aagggacatc cgataatatt aggtaggaag aaccttgaat
      241 caatcggaag agccttacct gacagaagaa atattattct gacgagagat aaggggttta
      301 cctttaatgg ttgtgaaatt gttcattcaa tagaagatgt ttttgagtta tgtaaaaacg
      361 aagaagaaat ttttattttc ggaggagaac agatttataa tttgtttttc ccttatgttg
      421 agaaaatgta catcacaaaa atacatcatg aattcgaagg agatactttt tttccagaag
      481 tgaattatga ggaatggaat gaggtatttg cccaaaaagg gataaagaat gataaaaatc
      541 cgtataacta ctattttcat gtatatgaaa gaaaaaactt attgagttaa cgggtgcgtt
      601 aattgaagaa gaacagtaaa gataaagcac aagagcttgg gattactcca agctcttttt
      661 gtcatttgaa ataaattata tctttccaat caaattgttt atctgtaatc cctaatcttt
      721 gagcaggtgt caaaaccttt ttatccgctg atttaaaagg gcgacaaaag ttgtagtaag
      781 ttcttagaat tgtaatcgca aattgagcat acttcggatt gaagttagcg taaatatagc
      841 tcttcttatc accacgagct gttgttaatg gtctttcaag agatgatata taacgtctta
      901 tctgttgaat aaagctattg gtcgaatggt cattaacatt taatagcatc tttgcgattt
      961 cgtttggttc cagagcagat aaatccgttc tacaatcaac tgaataaaat cctttatcct
     1021 tagtggctaa tggatgtttg atagggttat cggcatattt gcgatatctt tctccatctt
     1081 tactaatagc ctcttcgtgg aattgatgac ttgttagtaa ttcagttaga taatgagatg
     1141 ccaaagtccg tagaaacttt gttttgaatc ctctgatatc tccccaatcg agcagttctg
     1201 cttttgcttg tccgaattct tttaagcatt gttttctgct tttcgtcttg ttaacttggc
     1261 aaataaaatg atgtgcatcg ctcaacctta attctttcgt gaatactcta taaaaggcgt
     1321 ttctaataga gaagtcatca tcactaatca ttcgccattc gtcggcatta accatttgtt
     1381 taattaacca atagtgagca gttgtagtat aaggagcatc aacatttaaa ccatcgacaa
     1441 atctactcct attagtaatt ttccctaatt cgtgaagata agcattccta ttttcgctat
     1501 cgttagcgga tggttcttgt ggataataag accaatctaa cctatcattt ttacgactaa
     1561 aagtattgag atggtcttct ttgaattttc ttgtatcttc atttaattca tccattgaaa
     1621 tattccaatc ataggcaaca tcagaacgga acacatatct tgataagacc tcagcagata
     1681 caactatata cgtttgcata ttaaggtctt caaaccccgt atatttcttt gaaccttgtc
     1741 ctttcttacg gacgttattt aggtagtagt gcatcttgtc cgtattaagc cacatctcgt
     1801 taaatttctt tgtttgaagg ggttgtgtct catatcgttc taaaaactcc aaacaacgcc
     1861 tatacagcca ctccagctta tgatagtagg ttccaactcc aattcctaaa atatcacaag
     1921 tacgactgac tgaaaccctt ccaacaacca tcttagcgaa cattggaaga atggtgttct
     1981 tttgttggtg ataagtagtg gtttcttctc tttttggtag aacattagtg aacttcttac
     2041 acgccttaca ttgatagcgt tgagatttgc ccctactttt cccccttttg taaaattgct
     2101 tcggctcatt gaatggggtt gattcttctt ccgagcagcc ttctttatga aattgataat
     2161 ctggctcaac atcttggatg ctattgattt ctataaggcg tttaatttct tcaacaacag
     2221 accaattaga taaaggggtt actgtacagt tttgcgatac acctctgcca ataggattgt
     2281 cattgcagta cataccttta tgacctttat ctttggaact accagtcatt ttatatcgac
     2341 ttggtttccc ttttacatct ttgaatttgt gctgttcttt cccaaaatta caacaaaacg
     2401 gattgatgca gtaattatat tgaatgggat attcagaacc gttccattta aaagacgttg
     2461 gcaagaacaa cattttgtta taccttgttg caaatcgttt tggagttaat aaatcatatt
     2521 gtttagccct atcttttaat tcttcgtttg aaatcggaat tttaacatct acaatttcat
     2581 cttccttcgt ggctaatctt ttaagcttgg tcattgtcta tcaacccact ctatctttga
     2641 tacccatttt ttcaacaatc cgcttattac ttcgcttgtt ggcaatccat tcaataaact
     2701 tcttatcgtc taaaatgttc aataagaatt catccactgc ttcgctttca gtacgctctg
     2761 catattcagc gtattgctta actatcaccc ttacttgctc tgatatttcc caatccacag
     2821 acttagcgtt cttatttttt ggctcaagaa attgcatagg aaaatgcacc cctttttgct
     2881 tagtaaattg taaccatttt aacacaccaa tttgcattcc tacaataatt atttcacgtt
     2941 cgcattttta tatacatttt aacttacatt ttgtggtgta aattaacaac aaacgttgat
     3001 ttaacaataa aaaacgagta tcaaattcag ttgcaatttg atactcattt aggtttacat
     3061 tttcactttt tgtactccaa aactgaacta cttaa
//
LOCUS       DBGZHO010000199         2517 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.138, whole genome shotgun sequence.
ACCESSION   DBGZHO010000199 DBGZHO010000000
VERSION     DBGZHO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.138"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..423
                     /locus_tag="ACN3HL_003004"
     CDS             <1..423
                     /locus_tag="ACN3HL_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HHC8007769.1"
                     /translation="PYLIVDLKLCNRTTRITRSTQDLFELIDNIRDKKASLKSLKDTW
                     LDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAG
                     MNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            637..1332
                     /gene="vanR-A"
                     /locus_tag="ACN3HL_003005"
     CDS             637..1332
                     /gene="vanR-A"
                     /locus_tag="ACN3HL_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HHC8007770.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1310..2464
                     /locus_tag="ACN3HL_003006"
     CDS             1310..2464
                     /locus_tag="ACN3HL_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HHC8007771.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          866 a          449 c          529 g          673 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ctcgaatcac tcgtagtaca
       61 caagatctat ttgaattaat cgataacata cgagataaaa aggcaagttt aaaatcacta
      121 aaagatacat ggcttgattt atcagaagat aatccataca gccaattctt aattactgta
      181 atggctggtg ttaaccaatt agagcgagat cttattcgga tgagacaacg tgaagggatt
      241 gaattggcta agaaagaagg aaagtttaaa ggtcgattaa agaagtatca taaaaatcac
      301 gcaggaatga attatgcggt aaagctatat aaagaaggaa atatgactgt aaatcaaatt
      361 tgtgaaatta ctaatgtatc tagggcttca ttatacagga aattatcaga agtgaataat
      421 tagccattct gtattccgct aatgggcaat atttttaaag aagaaaagga aactataaaa
      481 tattaacagc ctcctagcga tgccgaaaag ccctttgata aaaaaagaat catcatctta
      541 agaaattctt agtcatttat tatgtaaatg cttataaatt cggccctata atctgataaa
      601 ttattaaggg caaacttatg tgaaagggtg ataactatga gcgataaaat acttattgtg
      661 gatgatgaac atgaaattgc cgatttggtt gaattatact taaaaaacga gaattatacg
      721 gttttcaaat actataccgc caaagaagca ttggaatgta tagacaagtc tgagattgac
      781 cttgccatat tggacatcat gcttcccggc acaagcggcc ttactatctg tcaaaaaata
      841 agggacaagc acacctatcc gattatcatg ctgaccggga aagatacaga ggtagataaa
      901 attacagggt taacaatcgg cgcggatgat tatataacga agccctttcg cccactggag
      961 ttaattgctc gggtaaaggc ccagttgcgc cgatacaaaa aattcagtgg agtaaaggag
     1021 cagaacgaaa atgttatcgt ccactccggc cttgtcatta atgttaacac ccatgagtgt
     1081 tatctgaacg agaagcagtt atcccttact cccaccgagt tttcaatact gcgaatcctc
     1141 tgtgaaaaca aggggaatgt ggttagctcc gagctgctat ttcatgagat atggggcgac
     1201 gaatatttca gcaagagcaa caacaccatc accgtgcata tccggcattt gcgcgaaaaa
     1261 atgaacgaca ccattgataa tccgaaatat ataaaaacgg tatggggggt tggttataaa
     1321 attgaaaaat aaaaaaaacg actattccaa actagaacga aaactttaca tgtatatcgt
     1381 tgcaattgtt gtggtagcaa ttgtattcgt gttgtatatt cgttcaatga tccgagggaa
     1441 acttggggat tggatcttaa gtattttgga aaacaaatat gacttaaatc acctggacgc
     1501 gatgaaatta tatcaatatt ccatacggaa caatatagat atctttattt atgtggcgat
     1561 tgtcattagt attcttattc tatgtcgcgt catgctttca aaattcgcaa aatactttga
     1621 cgagataaat accggcattg atgtacttat tcagaacgaa gataaacaaa ttgagctttc
     1681 tgcggaaatg gatgttatgg aacaaaagct caacacatta aaacggactc tggaaaagcg
     1741 agagcaggat gcaaagctgg ccgaacaaag aaaaaatgac gttgttatgt acttggcgca
     1801 cgatattaaa acgcccctta catccattat cggttatttg agcctgcttg acgaggctcc
     1861 agacatgccg gtagatcaaa aggcaaagta tgtgcatatc acgttggaca aagcgtatcg
     1921 actcgaacag ctaatcgacg agttttttga gattacacgg tataacctac aaacgataac
     1981 gctaacaaaa acgcacatag acctatacta tatgctggtg cagatgaccg atgaatttta
     2041 tcctcagctt tccgcacatg gaaaacaggc ggttattcac gcccccgagg atctgaccgt
     2101 gtccggcgac cctgataaac tcgcgagagt ctttaacaac attttgaaaa acgccgctgc
     2161 atacagtgag gataacagca tcattgacat taccgcgggc ctctccgggg atgtggtgtc
     2221 aatcgaattc aagaacactg gaagcatccc aaaagataag ctagctgcca tatttgaaaa
     2281 gttctatagg ctggacaatg ctcgttcttc cgatacgggt ggcgcgggac ttggattggc
     2341 gattgcaaaa gaaattattg ttcagcatgg agggcagatt tacgcggaaa gcaatgataa
     2401 ctatacgacg tttagggtag agcttccagc gatgccagac ttggttgata aaaggaggtc
     2461 ctaagagatg tatataattt tggctctttg tcaaatgatg ttggtaaaga gaaatct
//
LOCUS       DBGZHO010000200         1548 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.149, whole genome shotgun sequence.
ACCESSION   DBGZHO010000200 DBGZHO010000000
VERSION     DBGZHO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.149"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            complement(39..341)
                     /locus_tag="ACN3HL_003007"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACN3HL_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACN3HL_003008"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACN3HL_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACN3HL_003009"
     CDS             complement(1055..1345)
                     /locus_tag="ACN3HL_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HHC8007772.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          499 a          297 c          216 g          536 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagattt aagtagttca gttttggagt acaaaaagtg aaaatgta
//
LOCUS       DBGZHO010000201         1136 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.170, whole genome shotgun sequence.
ACCESSION   DBGZHO010000201 DBGZHO010000000
VERSION     DBGZHO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.170"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            <1..1120
                     /locus_tag="ACN3HL_003010"
                     /note="aph(2'')-Ia"
     CDS             <1..1120
                     /locus_tag="ACN3HL_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HHC8007773.1"
                     /translation="GFYSLFKTLQQNRTRYIKLIFEFLKKERNANAVILDPHKNNPRA
                     IRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKV
                     DSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNI
                     EYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDIS
                     ECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFS
                     CNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDI
                     EKAKEYQDIVEEYYPIETIVYGIKNIKQEFIESVKYFV"
BASE COUNT          477 a           91 c          188 g          380 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt acaagatata ttaaattgat
       61 ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa
      121 taatccaaga gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc
      181 agaacatgaa ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga
      241 tgataatgcc acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt
      301 caaagtagat agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa
      361 taatgaatac atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga
      421 aaaagcaata tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat
      481 tgaatattcg tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac
      541 ttttttaaca ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg
      601 agatattgcc agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg
      661 tactattgat aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta
      721 taatgattta actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc
      781 aacaacagtt tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct
      841 attgttagat ggcaataata gattaactgg aataattgat tttggagatt ctggaattat
      901 agatgaatat tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa
      961 ttttggagaa gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata
     1021 tcaagatata gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat
     1081 taaacaggaa tttatcgaga gtgtaaaata ttttgtgtaa atgaaaaaat ccatac
//
LOCUS       DBGZHO010000202         1044 bp    DNA     linear   BCT 26-MAR-2025
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_iso_205
            SAMN46017700-rid25550833.guided.173, whole genome shotgun sequence.
ACCESSION   DBGZHO010000202 DBGZHO010000000
VERSION     DBGZHO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN46017700
            Sequence Read Archive: SRR31855341
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002654841.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002654841.1
            Genome Coverage       :: 520x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2025 20:39:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,012
            CDSs (total)                      :: 2,961
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 102
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 102
            Pseudo Genes (frameshifted)       :: 50 of 102
            Pseudo Genes (incomplete)         :: 52 of 102
            Pseudo Genes (internal stop)      :: 30 of 102
            Pseudo Genes (multiple problems)  :: 24 of 102
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN46017700-rid25550833.guided.173"
                     /isolate="VRE_iso_205"
                     /isolation_source="Participant groin, Facility 2000"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="USA: Ohio"
                     /collection_date="2021-07"
                     /collected_by="University of Michigan"
     gene            87..146
                     /gene="ermCL"
                     /locus_tag="ACN3HL_003011"
     CDS             87..146
                     /gene="ermCL"
                     /locus_tag="ACN3HL_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HHC8007774.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            206..940
                     /locus_tag="ACN3HL_003012"
     CDS             206..940
                     /locus_tag="ACN3HL_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HHC8007775.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          420 a          138 c          140 g          346 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaacca gcttgtgcta taattattct
       61 aatttcataa aaaggagaat taatatatgg gcatttttag tatttttgta atcaacacag
      121 ttcattatca accaaacaaa aaataagtgg ttataatgga ttgttaatat aaacattcat
      181 tataacctca taggagtggg ttataatgaa caaaaaaaat ataaaagata gtcaaaactt
      241 tattacttca aagcatcata taaatgaaat tttgagaaat gtacatttaa atacaaatga
      301 taatattatt gagattggtt cagggaaagg tcatttcacg tttgaattag ctaaaaggtg
      361 taattatgta accgccattg aaatagatcc taaattatgt aggataacta aaaacaaact
      421 tattgaatat gagaacttcc aggttatcaa taaagatatt ttacaattta agtttcctaa
      481 aaataagtca tataagatat atggaaatat accctacaat ataagtacag atataattcg
      541 aaaaattgtt tttgaaagca cagctacaga aagttattta atagtggaat atggatttgc
      601 taaaaggttg ctaaatacaa atcgttcact agcactattt ttaatgacag aagttgatat
      661 atccatatta agtaaaatcc ctagagaata ctttcatcca aaacctagag ttaatagctc
      721 gttaattgta ttaaaaagac acccttcaaa aatatcactc aaagatagaa aacaatatga
      781 aaattttgtt atgaaatggg ttaacaaaga atacataaaa ctattttcca aaaaccaatt
      841 ttatcaagcc ttaaaatatg caagaattga cgatttaaac aatattagct ttgaacaatt
      901 cttgtctctt ttcaatagct ataaattatt taatagataa gttaaggggt gcataaactg
      961 catcccttaa cttatcttat tttgcttaaa caatcttggc ccgtaaactg cataactcat
     1021 atgtaaatcg ctccttttta ggtg
//
